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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1805128
log Bayes Factor = 7.21284
Chromosome 21   position 35,821,680  (GRCh37) Explore rs1805128 on Ensembl!
Variant rs1805128 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.992 0.008 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
D50-D53 Nutritional anaemias
0.987 0.013 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.984 0.016 0.000
D50 Iron deficiency anaemia
0.981 0.019 0.000
J30-J39 Other diseases of upper respiratory tract
0.974 0.026 0.000
D50.9 Iron deficiency anaemia, unspecified
0.973 0.027 0.000
M23 Internal derangement of knee
0.969 0.031 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.967 0.033 0.000
J09-J18 Influenza and pneumonia
0.962 0.038 0.000
J34 Other disorders of nose and nasal sinuses
0.960 0.040 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.953 0.047 0.000
M45-M49 Spondylopathies
0.953 0.047 0.000
M23.3 Other meniscus derangements
0.940 0.060 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.939 0.061 0.000
J18 Pneumonia, organism unspecified
0.938 0.062 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.925 0.075 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.921 0.079 0.000
J18.9 Pneumonia, unspecified
0.918 0.082 0.000
Chapter I Certain infectious and parasitic diseases
0.916 0.084 0.000
M15-M19 Arthrosis
0.911 0.089 0.000
O60-O75 Complications of labour and delivery
0.909 0.091 0.000
Chapter VI Diseases of the nervous system
0.904 0.096 0.000
M25 Other joint disorders, not elsewhere classified
0.902 0.098 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.901 0.099 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.901 0.099 0.000
M54 Dorsalgia
0.900 0.100 0.000
Chapter VII Diseases of the eye and adnexa
0.899 0.101 0.000
J34.2 Deviated nasal septum
0.891 0.109 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.888 0.112 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.880 0.120 0.000
S80-S89 Injuries to the knee and lower leg
0.879 0.120 0.000
E20-E35 Disorders of other endocrine glands
0.879 0.121 0.000
S20-S29 Injuries to the thorax
0.876 0.124 0.000
M51 Other intervertebral disk disorders
0.870 0.130 0.000
M31 Other necrotising vasculopathies
0.869 0.131 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.861 0.139 0.000
M48 Other spondylopathies
0.860 0.140 0.000
D51 Vitamin B12 deficiency anaemia
0.856 0.144 0.000
A00-A09 Intestinal infectious diseases
0.855 0.145 0.000
H53-H54 Visual disturbances and blindness
0.845 0.155 0.000
Chapter VIII Diseases of the ear and mastoid process
0.839 0.161 0.000
J00-J06 Acute upper respiratory infections
0.838 0.162 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.837 0.163 0.000
M25.5 Pain in joint
0.829 0.171 0.000
M17 Gonarthrosis [arthrosis of knee]
0.825 0.175 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.177 0.000
D50.8 Other iron deficiency anaemias
0.823 0.177 0.000
S40-S49 Injuries to the shoulder and upper arm
0.820 0.180 0.000
M47 Spondylosis
0.813 0.187 0.000
H53 Visual disturbances
0.810 0.190 0.000
G90-G99 Other disorders of the nervous system
0.808 0.191 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.808 0.192 0.000
M16 Coxarthrosis [arthrosis of hip]
0.807 0.193 0.000
M40-M43 Deforming dorsopathies
0.805 0.195 0.000
O48 Prolonged pregnancy
0.805 0.195 0.000
Chapter XX External causes of morbidity and mortality
0.805 0.195 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.804 0.196 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.794 0.206 0.000
M17.9 Gonarthrosis, unspecified
0.793 0.207 0.000
M48.0 Spinal stenosis
0.793 0.207 0.000
E50-E64 Other nutritional deficiencies
0.792 0.208 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.791 0.209 0.000
M24 Other specific joint derangements
0.791 0.209 0.000
M54.5 Low back pain
0.789 0.211 0.000
J35 Chronic diseases of tonsils and adenoids
0.786 0.214 0.000
D80-D89 Certain disorders involving the immune mechanism
0.783 0.217 0.000
M31.6 Other giant cell arteritis
0.780 0.220 0.000
H43-H45 Disorders of vitreous body and globe
0.780 0.220 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.778 0.222 0.000
M35 Other systemic involvement of connective tissue
0.777 0.223 0.000
M51.2 Other specified intervertebral disk displacement
0.776 0.224 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.775 0.225 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.773 0.227 0.000
J40-J47 Chronic lower respiratory diseases
0.773 0.227 0.000
B15-B19 Viral hepatitis
0.771 0.229 0.000
M45 Ankylosing spondylitis
0.770 0.230 0.000
M86-M90 Other osteopathies
0.770 0.230 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.768 0.231 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.766 0.234 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.764 0.236 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.764 0.236 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.761 0.239 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.761 0.239 0.000
M80-M85 Disorders of bone density and structure
0.760 0.240 0.000
O72 Postpartum haemorrhage
0.756 0.244 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
M54.9 Dorsalgia, unspecified
0.754 0.246 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.751 0.249 0.000
S50-S59 Injuries to the elbow and forearm
0.748 0.252 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.747 0.253 0.000
M54.59 Low back pain (Site unspecified)
0.746 0.254 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.744 0.256 0.000
E22 Hyperfunction of pituitary gland
0.744 0.256 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.744 0.256 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.738 0.262 0.000
E27 Other disorders of adrenal gland
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.736 0.264 0.000
M21 Other acquired deformities of limbs
0.733 0.267 0.000
J18.1 Lobar pneumonia, unspecified
0.728 0.272 0.000
M50 Cervical disk disorders
0.728 0.272 0.000
A08 Viral and other specified intestinal infections
0.728 0.272 0.000
O47 False labour
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
J30 Vasomotor and allergic rhinitis
0.725 0.274 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.723 0.277 0.000
M16.9 Coxarthrosis, unspecified
0.723 0.277 0.000
T81 Complications of procedures, not elsewhere classified
0.723 0.277 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
H30-H36 Disorders of choroid and retina
0.721 0.279 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.720 0.280 0.000
J38.3 Other diseases of vocal cords
0.720 0.280 0.000
L60-L75 Disorders of skin appendages
0.720 0.280 0.000
T66-T78 Other and unspecified effects of external causes
0.719 0.281 0.000
T39.1 4-Aminophenol derivatives
0.718 0.282 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.718 0.282 0.000
M25.56 Pain in joint (Lower leg)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M25.4 Effusion of joint
0.716 0.284 0.000
Chapter XXII Codes for special purposes
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.711 0.289 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.289 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
H53.1 Subjective visual disturbances
0.711 0.289 0.000
M47.8 Other spondylosis
0.711 0.289 0.000
J38.2 Nodules of vocal cords
0.711 0.289 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
S81 Open wound of lower leg
0.710 0.290 0.000
J84 Other interstitial pulmonary diseases
0.710 0.290 0.000
M54.2 Cervicalgia
0.708 0.292 0.000
D53 Other nutritional anaemias
0.707 0.292 0.000
D52 Folate deficiency anaemia
0.707 0.292 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.707 0.293 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.706 0.294 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.706 0.294 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.706 0.294 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.706 0.294 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.706 0.294 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.706 0.294 0.000
E23 Hypofunction and other disorders of pituitary gland
0.705 0.295 0.000
M22 Disorders of patella
0.703 0.297 0.000
D50.1 Sideropenic dysphagia
0.703 0.297 0.000
J00 Acute nasopharyngitis [common cold]
0.703 0.297 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.702 0.298 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.702 0.298 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.701 0.299 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
J37 Chronic laryngitis and laryngotracheitis
0.698 0.302 0.000
S72 Fracture of femur
0.696 0.304 0.000
M23.9 Internal derangement of knee, unspecified
0.695 0.305 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.695 0.305 0.000
M23.5 Chronic instability of knee
0.695 0.305 0.000
M23.4 Loose body in knee
0.695 0.305 0.000
M23.1 Discoid meniscus (congenital)
0.695 0.305 0.000
M23.0 Cystic meniscus
0.695 0.305 0.000
M53 Other dorsopathies, not elsewhere classified
0.695 0.305 0.000
A02 Other Salmonella infections
0.694 0.306 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.693 0.307 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.693 0.307 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.693 0.307 0.000
H10-H13 Disorders of conjunctiva
0.691 0.308 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.691 0.309 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.690 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.690 0.310 0.000
J17 Pneumonia in diseases classified elsewhere
0.689 0.310 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.689 0.310 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.689 0.310 0.000
J12 Viral pneumonia, not elsewhere classified
0.689 0.310 0.000
J11 Influenza, virus not identified
0.689 0.310 0.000
J10 Influenza due to identified influenza virus
0.689 0.310 0.000
J14 Pneumonia due to Haemophilus influenzae
0.689 0.310 0.000
J09 Influenza due to certain identified influenza virus
0.689 0.310 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.688 0.312 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.688 0.312 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.688 0.312 0.000
H53.8 Other visual disturbances
0.687 0.313 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.686 0.313 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
J34.3 Hypertrophy of nasal turbinates
0.686 0.314 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.684 0.315 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.684 0.315 0.000
G40-G47 Episodic and paroxysmal disorders
0.684 0.316 0.000
O63 Long labour
0.684 0.316 0.000
O85-O92 Complications predominantly related to the puerperium
0.683 0.316 0.000
M49 Spondylopathies in diseases classified elsewhere
0.683 0.317 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.683 0.317 0.000
S27 Injury of other and unspecified intrathoracic organs
0.682 0.318 0.000
Chapter XIV Diseases of the genitourinary system
0.681 0.319 0.000
O36 Maternal care for other known or suspected foetal problems
0.680 0.320 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.680 0.320 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.680 0.320 0.000
H65-H75 Diseases of middle ear and mastoid
0.679 0.321 0.000
E10-E14 Diabetes mellitus
0.679 0.321 0.000
H53.4 Visual field defects
0.679 0.321 0.000
H43 Disorders of vitreous body
0.679 0.321 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.678 0.322 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.678 0.322 0.000
O66 Other obstructed labour
0.678 0.322 0.000
M46 Other inflammatory spondylopathies
0.677 0.322 0.000
E65-E68 Obesity and other hyperalimentation
0.675 0.325 0.000
M23.37 Other meniscus derangements-Capsular lig
0.674 0.326 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.674 0.326 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.674 0.326 0.000
H55-H59 Other disorders of eye and adnexa
0.673 0.327 0.000
H60-H62 Diseases of external ear
0.673 0.327 0.000
E29 Testicular dysfunction
0.672 0.328 0.000
J18.8 Other pneumonia, organism unspecified
0.672 0.328 0.000
J18.2 Hypostatic pneumonia, unspecified
0.672 0.328 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.672 0.328 0.000
M54.3 Sciatica
0.671 0.329 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.671 0.329 0.000
J38.7 Other diseases of larynx
0.671 0.329 0.000
E55 Vitamin D deficiency
0.671 0.329 0.000
O80-O84 Delivery
0.669 0.331 0.000
O00-O08 Pregnancy with abortive outcome
0.668 0.332 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.668 0.332 0.000
B18 Chronic viral hepatitis
0.667 0.332 0.000
J39 Other diseases of upper respiratory tract
0.666 0.334 0.000
S20 Superficial injury of thorax
0.665 0.334 0.000
G96 Other disorders of central nervous system
0.664 0.336 0.000
E40-E46 Malnutrition
0.663 0.337 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.663 0.337 0.000
G62 Other polyneuropathies
0.662 0.338 0.000
J01 Acute sinusitis
0.661 0.339 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.660 0.340 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.659 0.341 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.658 0.341 0.000
M43 Other deforming dorsopathies
0.657 0.343 0.000
G20-G26 Extrapyramidal and movement disorders
0.657 0.343 0.000
B99-B99 Other infectious diseases
0.657 0.343 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.657 0.343 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.657 0.343 0.000
B65-B83 Helminthiases
0.657 0.343 0.000
B50-B64 Protozoal diseases
0.657 0.343 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.657 0.343 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.657 0.343 0.000
A80-A89 Viral infections of the central nervous system
0.657 0.343 0.000
A75-A79 Rickettsioses
0.657 0.343 0.000
A70-A74 Other diseases caused by chlamydiae
0.657 0.343 0.000
A65-A69 Other spirochaetal diseases
0.657 0.343 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.657 0.343 0.000
A20-A28 Certain zoonotic bacterial diseases
0.657 0.343 0.000
A15-A19 Tuberculosis
0.657 0.343 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.657 0.343 0.000
J60-J70 Lung diseases due to external agents
0.655 0.344 0.000
M35.3 Polymyalgia rheumatica
0.655 0.345 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.654 0.346 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.654 0.346 0.000
O62 Abnormalities of forces of labour
0.653 0.347 0.000
M15 Polyarthrosis
0.653 0.347 0.000
O74 Complications of anaesthesia during labour and delivery
0.652 0.348 0.000
O73 Retained placenta and membranes, without haemorrhage
0.652 0.348 0.000
O71 Other obstetric trauma
0.652 0.348 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.652 0.348 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.652 0.348 0.000
O61 Failed induction of labour
0.652 0.348 0.000
O60 Preterm delivery
0.652 0.348 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.650 0.350 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.649 0.351 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.649 0.351 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.649 0.351 0.000
B35-B49 Mycoses
0.649 0.351 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.649 0.351 0.000
G70-G73 Diseases of myoneural junction and muscle
0.648 0.352 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.648 0.352 0.000
M25.9 Joint disorder, unspecified
0.647 0.353 0.000
M25.8 Other specified joint disorders
0.647 0.353 0.000
M25.3 Other instability of joint
0.647 0.353 0.000
M25.2 Flail joint
0.647 0.353 0.000
M25.1 Fistula of joint
0.647 0.353 0.000
M25.0 Haemarthrosis
0.647 0.353 0.000
E22.1 Hyperprolactinaemia
0.647 0.353 0.000
O42 Premature rupture of membranes
0.647 0.353 0.000
M54.4 Lumbago with sciatica
0.646 0.354 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.354 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.646 0.354 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.646 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
T36 Poisoning by systemic antibiotics
0.646 0.354 0.000
O72.1 Other immediate postpartum haemorrhage
0.646 0.354 0.000
M24.1 Other articular cartilage disorders
0.646 0.354 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.646 0.354 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.646 0.354 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.646 0.354 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.646 0.354 0.000
T83.2 Mechanical complication of graft of urinary organ
0.646 0.354 0.000
M54.8 Other dorsalgia
0.645 0.355 0.000
M54.6 Pain in thoracic spine
0.645 0.355 0.000
M54.0 Panniculitis affecting regions of neck and back
0.645 0.355 0.000
J18.0 Bronchopneumonia, unspecified
0.645 0.355 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.645 0.355 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.644 0.356 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.644 0.356 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.644 0.356 0.000
S82 Fracture of lower leg, including ankle
0.644 0.356 0.000
M23.8 Other internal derangements of knee
0.643 0.357 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.643 0.357 0.000
M25.51 Pain in joint (Shoulder region)
0.642 0.357 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.640 0.360 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.639 0.361 0.000
D60-D64 Aplastic and other anaemias
0.639 0.361 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.638 0.361 0.000
G90 Disorders of autonomic nervous system
0.638 0.362 0.000
M50.2 Other cervical disk displacement
0.638 0.362 0.000
M18 Arthrosis of first carpometacarpal joint
0.638 0.362 0.000
S80 Superficial injury of lower leg
0.637 0.363 0.000
J90-J94 Other diseases of pleura
0.637 0.363 0.000
H53.0 Amblyopia ex anopsia
0.637 0.363 0.000
O45 Premature separation of placenta [abruptio placentae]
0.637 0.363 0.000
O44 Placenta praevia
0.637 0.363 0.000
O43 Placental disorders
0.637 0.363 0.000
O41 Other disorders of amniotic fluid and membranes
0.637 0.363 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.637 0.363 0.000
O33 Maternal care for known or suspected disproportion
0.637 0.363 0.000
O31 Complications specific to multiple gestation
0.637 0.363 0.000
O30 Multiple gestation
0.637 0.363 0.000
O40 Polyhydramnios
0.637 0.363 0.000
A08.4 Viral intestinal infection, unspecified
0.637 0.363 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.636 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.635 0.365 0.000
G30-G32 Other degenerative diseases of the nervous system
0.634 0.366 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.633 0.367 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.633 0.367 0.000
M48.02 Spinal stenosis (Cervical region)
0.632 0.368 0.000
J32 Chronic sinusitis
0.631 0.369 0.000
S89 Other and unspecified injuries of lower leg
0.631 0.369 0.000
S88 Traumatic amputation of lower leg
0.631 0.369 0.000
S87 Crushing injury of lower leg
0.631 0.369 0.000
S86 Injury of muscle and tendon at lower leg level
0.631 0.369 0.000
S85 Injury of blood vessels at lower leg level
0.631 0.369 0.000
S84 Injury of nerves at lower leg level
0.631 0.369 0.000
M05-M14 Inflammatory polyarthropathies
0.630 0.370 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.630 0.370 0.000
E34 Other endocrine disorders
0.630 0.370 0.000
E32 Diseases of thymus
0.630 0.370 0.000
E31 Polyglandular dysfunction
0.630 0.370 0.000
E30 Disorders of puberty, not elsewhere classified
0.630 0.370 0.000
E28 Ovarian dysfunction
0.630 0.370 0.000
E26 Hyperaldosteronism
0.630 0.370 0.000
E25 Adrenogenital disorders
0.630 0.370 0.000
E24 Cushing's syndrome
0.630 0.370 0.000
E20 Hypoparathyroidism
0.630 0.370 0.000
J45 Asthma
0.630 0.370 0.000
S29 Other and unspecified injuries of thorax
0.628 0.372 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.628 0.372 0.000
S26 Injury of heart
0.628 0.372 0.000
S25 Injury of blood vessels of thorax
0.628 0.372 0.000
S24 Injury of nerves and spinal cord at thorax level
0.628 0.372 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.628 0.372 0.000
S21 Open wound of thorax
0.628 0.372 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.626 0.374 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.626 0.374 0.000
L60 Nail disorders
0.626 0.374 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.626 0.374 0.000
H53.2 Diplopia
0.626 0.374 0.000
J42 Unspecified chronic bronchitis
0.624 0.376 0.000
M25.57 Pain in joint (Ankle and foot)
0.624 0.376 0.000
M51.3 Other specified intervertebral disk degeneration
0.624 0.376 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.624 0.376 0.000
M51.9 Intervertebral disk disorder, unspecified
0.624 0.376 0.000
M51.8 Other specified intervertebral disk disorders
0.624 0.376 0.000
M51.4 Schmorl's nodes
0.624 0.376 0.000
M31.9 Necrotising vasculopathy, unspecified
0.623 0.377 0.000
M31.8 Other specified necrotising vasculopathies
0.623 0.377 0.000
M31.7 Microscopic polyangiitis
0.623 0.377 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.623 0.377 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.623 0.377 0.000
M31.3 Wegener's granulomatosis
0.623 0.377 0.000
M31.2 Lethal midline granuloma
0.623 0.377 0.000
M31.1 Thrombotic microangiopathy
0.623 0.377 0.000
M31.0 Hypersensitivity angiitis
0.623 0.377 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.621 0.379 0.000
N17-N19 Renal failure
0.621 0.379 0.000
N99-N99 Other disorders of the genitourinary system
0.620 0.380 0.000
J35.0 Chronic tonsillitis
0.618 0.381 0.000
B25-B34 Other viral diseases
0.618 0.382 0.000
M87 Osteonecrosis
0.617 0.383 0.000
J38.6 Stenosis of larynx
0.617 0.383 0.000
J38.5 Laryngeal spasm
0.617 0.383 0.000
J38.4 Oedema of larynx
0.617 0.383 0.000
J38.0 Paralysis of vocal cords and larynx
0.617 0.383 0.000
M16.7 Other secondary coxarthrosis
0.617 0.383 0.000
M48.9 Spondylopathy, unspecified
0.616 0.383 0.000
M48.8 Other specified spondylopathies
0.616 0.383 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.616 0.383 0.000
M48.4 Fatigue fracture of vertebra
0.616 0.383 0.000
M48.3 Traumatic spondylopathy
0.616 0.383 0.000
M48.2 Kissing spine
0.616 0.383 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.616 0.383 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.615 0.385 0.000
E53 Deficiency of other B group vitamins
0.615 0.385 0.000
H90-H95 Other disorders of ear
0.614 0.385 0.000
T51 Toxic effect of alcohol
0.614 0.386 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.614 0.386 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.614 0.386 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.614 0.386 0.000
D51.2 Transcobalamin II deficiency
0.614 0.386 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.614 0.386 0.000
A07 Other protozoal intestinal diseases
0.613 0.387 0.000
A06 Amoebiasis
0.613 0.387 0.000
A05 Other bacterial foodborne intoxications
0.613 0.387 0.000
A03 Shigellosis
0.613 0.387 0.000
A01 Typhoid and paratyphoid fevers
0.613 0.387 0.000
A00 Cholera
0.613 0.387 0.000
Y95 Nosocomial condition
0.613 0.387 0.000
H36 Retinal disorders in diseases classified elsewhere
0.612 0.388 0.000
N10-N16 Renal tubulo-interstitial diseases
0.612 0.388 0.000
B07 Viral warts
0.611 0.389 0.000
M48.06 Spinal stenosis (Lumbar region)
0.610 0.390 0.000
E10 Insulin-dependent diabetes mellitus
0.609 0.391 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.606 0.394 0.000
A30-A49 Other bacterial diseases
0.606 0.394 0.000
M25.53 Pain in joint (Forearm)
0.606 0.394 0.000
D73 Diseases of spleen
0.604 0.396 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.603 0.397 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.603 0.397 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.603 0.397 0.000
B02 Zoster [herpes zoster]
0.602 0.397 0.000
M54.1 Radiculopathy
0.602 0.398 0.000
H33 Retinal detachments and breaks
0.602 0.398 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.601 0.399 0.000
J04 Acute laryngitis and tracheitis
0.601 0.399 0.000
J35.1 Hypertrophy of tonsils
0.601 0.399 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.600 0.400 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.600 0.400 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.600 0.400 0.000
S22.4 Multiple fractures of ribs
0.600 0.400 0.000
J47 Bronchiectasis
0.600 0.400 0.000
S81.8 Open wound of other parts of lower leg
0.595 0.405 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.595 0.405 0.000
M25.59 Pain in joint (Site unspecified)
0.595 0.405 0.000
M25.58 Pain in joint (Other)
0.595 0.405 0.000
M25.52 Pain in joint (Upper arm)
0.595 0.405 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.594 0.406 0.000
B18.2 Chronic viral hepatitis C
0.593 0.407 0.000
S22.0 Fracture of thoracic vertebra
0.593 0.407 0.000
H44 Disorders of globe
0.592 0.408 0.000
M17.5 Other secondary gonarthrosis
0.592 0.408 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.592 0.408 0.000
M17.3 Other posttraumatic gonarthrosis
0.592 0.408 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.592 0.408 0.000
M41 Scoliosis
0.591 0.409 0.000
M48.09 Spinal stenosis (Site unspecified)
0.590 0.409 0.000
S79 Other and unspecified injuries of hip and thigh
0.590 0.410 0.000
S78 Traumatic amputation of hip and thigh
0.590 0.410 0.000
S77 Crushing injury of hip and thigh
0.590 0.410 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.590 0.410 0.000
S75 Injury of blood vessels at hip and thigh level
0.590 0.410 0.000
S74 Injury of nerves at hip and thigh level
0.590 0.410 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.590 0.410 0.000
S71 Open wound of hip and thigh
0.590 0.410 0.000
S70 Superficial injury of hip and thigh
0.590 0.410 0.000
T81.9 Unspecified complication of procedure
0.589 0.411 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.589 0.411 0.000
S48 Traumatic amputation of shoulder and upper arm
0.588 0.412 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.588 0.412 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.588 0.412 0.000
S44 Injury of nerves at shoulder and upper arm level
0.588 0.412 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.588 0.412 0.000
S41 Open wound of shoulder and upper arm
0.588 0.412 0.000
S40 Superficial injury of shoulder and upper arm
0.588 0.412 0.000
S47 Crushing injury of shoulder and upper arm
0.588 0.412 0.000
M47.86 Other spondylosis (Lumbar region)
0.588 0.412 0.000
M47.9 Spondylosis, unspecified
0.587 0.413 0.000
D86 Sarcoidosis
0.587 0.413 0.000
G62.9 Polyneuropathy, unspecified
0.586 0.414 0.000
E55.9 Vitamin D deficiency, unspecified
0.584 0.415 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.583 0.417 0.000
M47.2 Other spondylosis with radiculopathy
0.583 0.417 0.000
M47.1 Other spondylosis with myelopathy
0.583 0.417 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.583 0.417 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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