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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181609621
log Bayes Factor = 1.56948
Chromosome 12   position 32,810,759  (GRCh37) Explore rs181609621 on Ensembl!
Variant rs181609621 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.971 0.029 0.000
Chapter IX Diseases of the circulatory system
0.971 0.029 0.000
I20-I25 Ischaemic heart diseases
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.946 0.054 0.000
Chapter XIV Diseases of the genitourinary system
0.941 0.059 0.000
I25 Chronic ischaemic heart disease
0.938 0.062 0.000
I20 Angina pectoris
0.909 0.091 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.907 0.093 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.881 0.119 0.000
Chapter X Diseases of the respiratory system
0.861 0.139 0.000
Chapter VII Diseases of the eye and adnexa
0.860 0.140 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.857 0.143 0.000
I35 Nonrheumatic aortic valve disorders
0.848 0.152 0.000
I25.1 Atherosclerotic heart disease
0.830 0.170 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.825 0.175 0.000
I20.9 Angina pectoris, unspecified
0.820 0.180 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.812 0.188 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.799 0.201 0.000
I50 Heart failure
0.794 0.206 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.789 0.211 0.000
I24 Other acute ischaemic heart diseases
0.786 0.214 0.000
R07 Pain in throat and chest
0.785 0.215 0.000
R07.4 Chest pain, unspecified
0.781 0.219 0.000
Chapter V Mental and behavioural disorders
0.781 0.219 0.000
I31 Other diseases of pericardium
0.778 0.222 0.000
I51 Complications and ill-defined descriptions of heart disease
0.776 0.224 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.771 0.229 0.000
N20-N23 Urolithiasis
0.767 0.233 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
I35.1 Aortic (valve) insufficiency
0.760 0.240 0.000
Chapter VI Diseases of the nervous system
0.756 0.244 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.755 0.245 0.000
I25.2 Old myocardial infarction
0.754 0.246 0.000
N10-N16 Renal tubulo-interstitial diseases
0.753 0.247 0.000
S00-S09 Injuries to the head
0.753 0.247 0.000
N40-N51 Diseases of male genital organs
0.747 0.253 0.000
I20.0 Unstable angina
0.741 0.259 0.000
Chapter XX External causes of morbidity and mortality
0.739 0.261 0.000
I21 Acute myocardial infarction
0.736 0.264 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.731 0.269 0.000
Chapter I Certain infectious and parasitic diseases
0.725 0.275 0.000
N60-N64 Disorders of breast
0.724 0.276 0.000
I20.8 Other forms of angina pectoris
0.724 0.276 0.000
J30-J39 Other diseases of upper respiratory tract
0.723 0.277 0.000
J09-J18 Influenza and pneumonia
0.721 0.279 0.000
I45 Other conduction disorders
0.719 0.281 0.000
M45-M49 Spondylopathies
0.719 0.281 0.000
I60-I69 Cerebrovascular diseases
0.715 0.285 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.710 0.290 0.000
N92 Excessive, frequent and irregular menstruation
0.708 0.292 0.000
Chapter VIII Diseases of the ear and mastoid process
0.708 0.292 0.000
H40-H42 Glaucoma
0.707 0.293 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.705 0.295 0.000
M70-M79 Other soft tissue disorders
0.700 0.300 0.000
N87 Dysplasia of cervix uteri
0.699 0.301 0.000
N93 Other abnormal uterine and vaginal bleeding
0.698 0.301 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.698 0.302 0.000
S50-S59 Injuries to the elbow and forearm
0.697 0.303 0.000
Chapter XXII Codes for special purposes
0.696 0.304 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.696 0.304 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.696 0.304 0.000
I05-I09 Chronic rheumatic heart diseases
0.696 0.304 0.000
I00-I02 Acute rheumatic fever
0.696 0.304 0.000
I44 Atrioventricular and left bundle-branch block
0.695 0.304 0.000
I47 Paroxysmal tachycardia
0.695 0.305 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.694 0.306 0.000
I23 Certain current complications following acute myocardial infarction
0.693 0.307 0.000
I22 Subsequent myocardial infarction
0.693 0.307 0.000
I10-I15 Hypertensive diseases
0.688 0.312 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.687 0.313 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.682 0.318 0.000
S80-S89 Injuries to the knee and lower leg
0.680 0.320 0.000
I52 Other heart disorders in diseases classified elsewhere
0.678 0.321 0.000
I49 Other cardiac arrhythmias
0.678 0.321 0.000
I48 Atrial fibrillation and flutter
0.678 0.321 0.000
I46 Cardiac arrest
0.678 0.321 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.678 0.321 0.000
I42 Cardiomyopathy
0.678 0.321 0.000
I41 Myocarditis in diseases classified elsewhere
0.678 0.321 0.000
I40 Acute myocarditis
0.678 0.321 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.678 0.321 0.000
I37 Pulmonary valve disorders
0.678 0.321 0.000
I36 Nonrheumatic tricuspid valve disorders
0.678 0.321 0.000
I33 Acute and subacute endocarditis
0.678 0.321 0.000
I32 Pericarditis in diseases classified elsewhere
0.678 0.321 0.000
I30 Acute pericarditis
0.678 0.321 0.000
I38 Endocarditis, valve unspecified
0.678 0.321 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.676 0.324 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.676 0.324 0.000
N80 Endometriosis
0.675 0.325 0.000
N99-N99 Other disorders of the genitourinary system
0.674 0.326 0.000
N25-N29 Other disorders of kidney and ureter
0.674 0.326 0.000
N00-N08 Glomerular diseases
0.674 0.326 0.000
I25.6 Silent myocardial ischaemia
0.673 0.327 0.000
I25.5 Ischaemic cardiomyopathy
0.673 0.327 0.000
I25.4 Coronary artery aneurysm
0.673 0.327 0.000
I25.3 Aneurysm of heart
0.673 0.327 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.673 0.327 0.000
N30-N39 Other diseases of urinary system
0.673 0.327 0.000
M20-M25 Other joint disorders
0.669 0.331 0.000
L60-L75 Disorders of skin appendages
0.669 0.331 0.000
I34 Nonrheumatic mitral valve disorders
0.664 0.336 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.661 0.339 0.000
T81 Complications of procedures, not elsewhere classified
0.660 0.340 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.659 0.341 0.000
I31.3 Pericardial effusion (noninflammatory)
0.657 0.343 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.657 0.343 0.000
I24.8 Other forms of acute ischaemic heart disease
0.657 0.343 0.000
M05-M14 Inflammatory polyarthropathies
0.656 0.344 0.000
I35.0 Aortic (valve) stenosis
0.655 0.345 0.000
N84 Polyp of female genital tract
0.653 0.347 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.652 0.348 0.000
I20.1 Angina pectoris with documented spasm
0.651 0.349 0.000
J20-J22 Other acute lower respiratory infections
0.651 0.349 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.650 0.350 0.000
T79-T79 Certain early complications of trauma
0.650 0.350 0.000
T66-T78 Other and unspecified effects of external causes
0.650 0.350 0.000
T33-T35 Frostbite
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.650 0.350 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.650 0.350 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.650 0.350 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.650 0.350 0.000
T00-T07 Injuries involving multiple body regions
0.650 0.350 0.000
S90-S99 Injuries to the ankle and foot
0.650 0.350 0.000
S70-S79 Injuries to the hip and thigh
0.650 0.350 0.000
S40-S49 Injuries to the shoulder and upper arm
0.650 0.350 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.650 0.350 0.000
S10-S19 Injuries to the neck
0.650 0.350 0.000
I50.9 Heart failure, unspecified
0.650 0.350 0.000
R01 Cardiac murmurs and other cardiac sounds
0.648 0.352 0.000
J00-J06 Acute upper respiratory infections
0.648 0.352 0.000
M65-M68 Disorders of synovium and tendon
0.648 0.352 0.000
N95 Menopausal and other perimenopausal disorders
0.644 0.356 0.000
N20 Calculus of kidney and ureter
0.643 0.357 0.000
S60-S69 Injuries to the wrist and hand
0.641 0.359 0.000
H04 Disorders of lachrymal system
0.639 0.361 0.000
I51.7 Cardiomegaly
0.637 0.363 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.637 0.363 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.635 0.365 0.000
N98 Complications associated with artificial fertilisation
0.632 0.368 0.000
N97 Female infertility
0.632 0.368 0.000
N91 Absent, scanty and rare menstruation
0.632 0.368 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.632 0.368 0.000
N89 Other noninflammatory disorders of vagina
0.632 0.368 0.000
N88 Other noninflammatory disorders of cervix uteri
0.632 0.368 0.000
N82 Fistulae involving female genital tract
0.632 0.368 0.000
N96 Habitual aborter
0.632 0.368 0.000
N86 Erosion and ectropion of cervix uteri
0.632 0.368 0.000
H25-H28 Disorders of lens
0.630 0.370 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.628 0.372 0.000
S00 Superficial injury of head
0.626 0.374 0.000
J18 Pneumonia, organism unspecified
0.621 0.379 0.000
N13 Obstructive and reflux uropathy
0.619 0.381 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.618 0.381 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.618 0.382 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.618 0.382 0.000
J60-J70 Lung diseases due to external agents
0.618 0.382 0.000
H55-H59 Other disorders of eye and adnexa
0.617 0.383 0.000
H53-H54 Visual disturbances and blindness
0.617 0.383 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.617 0.383 0.000
H43-H45 Disorders of vitreous body and globe
0.617 0.383 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.617 0.383 0.000
H10-H13 Disorders of conjunctiva
0.617 0.383 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.615 0.385 0.000
M91-M94 Chondropathies
0.615 0.385 0.000
M86-M90 Other osteopathies
0.615 0.385 0.000
M60-M63 Disorders of muscles
0.615 0.385 0.000
M40-M43 Deforming dorsopathies
0.615 0.385 0.000
M00-M03 Infectious arthropathies
0.615 0.385 0.000
M47 Spondylosis
0.611 0.389 0.000
R30-R39 Symptoms and signs involving the urinary system
0.609 0.391 0.000
I35.9 Aortic valve disorder, unspecified
0.608 0.392 0.000
I35.8 Other aortic valve disorders
0.608 0.392 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.608 0.392 0.000
H30-H36 Disorders of choroid and retina
0.608 0.392 0.000
I50.0 Congestive heart failure
0.605 0.395 0.000
N50 Other disorders of male genital organs
0.604 0.396 0.000
M50-M54 Other dorsopathies
0.603 0.397 0.000
J90-J94 Other diseases of pleura
0.601 0.399 0.000
N17-N19 Renal failure
0.597 0.402 0.000
H40 Glaucoma
0.597 0.403 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.597 0.403 0.000
R04 Haemorrhage from respiratory passages
0.597 0.403 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.596 0.404 0.000
J40-J47 Chronic lower respiratory diseases
0.594 0.406 0.000
I50.1 Left ventricular failure
0.593 0.407 0.000
G40-G47 Episodic and paroxysmal disorders
0.593 0.407 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.591 0.408 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.591 0.408 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.591 0.408 0.000
R47-R49 Symptoms and signs involving speech and voice
0.591 0.408 0.000
J95-J99 Other diseases of the respiratory system
0.591 0.409 0.000
J33 Nasal polyp
0.591 0.409 0.000
M75 Shoulder lesions
0.589 0.411 0.000
M80-M85 Disorders of bone density and structure
0.584 0.416 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.582 0.418 0.000
I51.8 Other ill-defined heart diseases
0.582 0.418 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.580 0.420 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.579 0.421 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.575 0.425 0.000
E70-E90 Metabolic disorders
0.575 0.425 0.000
I21.9 Acute myocardial infarction, unspecified
0.574 0.426 0.000
I61 Intracerebral haemorrhage
0.574 0.426 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.573 0.427 0.000
R02 Gangrene, not elsewhere classified
0.573 0.427 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.573 0.427 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.572 0.428 0.000
L20-L30 Dermatitis and eczema
0.572 0.428 0.000
N63 Unspecified lump in breast
0.569 0.430 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.568 0.431 0.000
J32 Chronic sinusitis
0.567 0.433 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.566 0.434 0.000
I21.4 Acute subendocardial myocardial infarction
0.566 0.434 0.000
Chapter II Neoplasms
0.565 0.435 0.000
E65-E68 Obesity and other hyperalimentation
0.565 0.435 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.564 0.436 0.000
I24.1 Dressler's syndrome
0.564 0.436 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.564 0.436 0.000
R07.1 Chest pain on breathing
0.563 0.437 0.000
R07.0 Pain in throat
0.563 0.437 0.000
F99-F99 Unspecified mental disorder
0.560 0.440 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.560 0.440 0.000
F80-F89 Disorders of psychological development
0.560 0.440 0.000
F70-F79 Mental retardation
0.560 0.440 0.000
F60-F69 Disorders of adult personality and behaviour
0.560 0.440 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.560 0.440 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.560 0.440 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.560 0.440 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.559 0.441 0.000
S09 Other and unspecified injuries of head
0.559 0.441 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.559 0.441 0.000
G90-G99 Other disorders of the nervous system
0.558 0.442 0.000
I31.9 Disease of pericardium, unspecified
0.558 0.442 0.000
I31.8 Other specified diseases of pericardium
0.558 0.442 0.000
I31.2 Haemopericardium, not elsewhere classified
0.558 0.442 0.000
I31.1 Chronic constrictive pericarditis
0.558 0.442 0.000
I31.0 Chronic adhesive pericarditis
0.558 0.442 0.000
F10.1 Harmful use
0.558 0.442 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.557 0.442 0.000
I45.1 Other and unspecified right bundle-branch block
0.556 0.443 0.000
B95-B98 Bacterial, viral and other infectious agents
0.556 0.444 0.000
I51.9 Heart disease, unspecified
0.556 0.444 0.000
I51.6 Cardiovascular disease, unspecified
0.556 0.444 0.000
I51.5 Myocardial degeneration
0.556 0.444 0.000
I51.4 Myocarditis, unspecified
0.556 0.444 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.556 0.444 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.556 0.444 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.556 0.444 0.000
I51.0 Cardiac septal defect, acquired
0.556 0.444 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.555 0.445 0.000
N92.3 Ovulation bleeding
0.555 0.445 0.000
L50-L54 Urticaria and erythema
0.553 0.447 0.000
L10-L14 Bullous disorders
0.553 0.447 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.552 0.448 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.552 0.448 0.000
N85.2 Hypertrophy of uterus
0.552 0.448 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.552 0.448 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.550 0.450 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.550 0.450 0.000
N21 Calculus of lower urinary tract
0.550 0.450 0.000
N23 Unspecified renal colic
0.550 0.450 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.550 0.450 0.000
S01 Open wound of head
0.549 0.450 0.000
S52 Fracture of forearm
0.547 0.453 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.547 0.453 0.000
T87 Complications peculiar to reattachment and amputation
0.547 0.453 0.000
T86 Failure and rejection of transplanted organs and tissues
0.547 0.453 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.547 0.453 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.547 0.453 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.547 0.453 0.000
G70-G73 Diseases of myoneural junction and muscle
0.542 0.458 0.000
G30-G32 Other degenerative diseases of the nervous system
0.542 0.458 0.000
G20-G26 Extrapyramidal and movement disorders
0.542 0.458 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.542 0.458 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.542 0.458 0.000
T51 Toxic effect of alcohol
0.541 0.458 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.541 0.459 0.000
N85.7 Haematometra
0.541 0.459 0.000
N85.6 Intra-uterine synechiae
0.541 0.459 0.000
N85.5 Inversion of uterus
0.541 0.459 0.000
N85.4 Malposition of uterus
0.541 0.459 0.000
N85.3 Subinvolution of uterus
0.541 0.459 0.000
N85.1 Endometrial adenomatous hyperplasia
0.541 0.459 0.000
N85.0 Endometrial glandular hyperplasia
0.541 0.459 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.540 0.460 0.000
N15 Other renal tubulo-interstitial diseases
0.540 0.460 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.540 0.460 0.000
N11 Chronic tubulo-interstitial nephritis
0.540 0.460 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.540 0.460 0.000
N10 Acute tubulo-interstitial nephritis
0.540 0.460 0.000
S08 Traumatic amputation of part of head
0.540 0.460 0.000
S07 Crushing injury of head
0.540 0.460 0.000
S06 Intracranial injury
0.540 0.460 0.000
S05 Injury of eye and orbit
0.540 0.460 0.000
S04 Injury of cranial nerves
0.540 0.460 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.540 0.460 0.000
S02 Fracture of skull and facial bones
0.540 0.460 0.000
R01.1 Cardiac murmur, unspecified
0.540 0.460 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.540 0.460 0.000
L40-L45 Papulosquamous disorders
0.539 0.461 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.538 0.462 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.536 0.464 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.536 0.464 0.000
N48 Other disorders of penis
0.536 0.464 0.000
N45 Orchitis and epididymitis
0.536 0.464 0.000
N43 Hydrocele and spermatocele
0.536 0.464 0.000
N42 Other disorders of prostate
0.536 0.464 0.000
N41 Inflammatory diseases of prostate
0.536 0.464 0.000
N46 Male infertility
0.536 0.464 0.000
N44 Torsion of testis
0.536 0.464 0.000
S00.8 Superficial injury of other parts of head
0.535 0.465 0.000
M47.8 Other spondylosis
0.534 0.466 0.000
M48 Other spondylopathies
0.533 0.467 0.000
N94.6 Dysmenorrhoea, unspecified
0.531 0.469 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.530 0.470 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.530 0.470 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.530 0.470 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.530 0.470 0.000
Y35-Y36 Legal intervention and operations of war
0.530 0.470 0.000
Y10-Y34 Event of undetermined intent
0.530 0.470 0.000
Y00-Y09 Assault
0.530 0.470 0.000
X85-X99 Assault
0.530 0.470 0.000
X60-X84 Intentional self-harm
0.530 0.470 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.530 0.470 0.000
X50-X57 Overexertion, travel and privation
0.530 0.470 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.530 0.470 0.000
X30-X39 Exposure to forces of nature
0.530 0.470 0.000
X20-X29 Contact with venomous animals and plants
0.530 0.470 0.000
X10-X19 Contact with heat and hot substances
0.530 0.470 0.000
X00-X09 Exposure to smoke, fire and flames
0.530 0.470 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.530 0.470 0.000
W75-W84 Other accidental threats to breathing
0.530 0.470 0.000
W65-W74 Accidental drowning and submersion
0.530 0.470 0.000
W50-W64 Exposure to animate mechanical forces
0.530 0.470 0.000
W20-W49 Exposure to inanimate mechanical forces
0.530 0.470 0.000
V98-V99 Other and unspecified transport accidents
0.530 0.470 0.000
V95-V97 Air and space transport accidents
0.530 0.470 0.000
V90-V94 Water transport accidents
0.530 0.470 0.000
V80-V89 Other land transport accidents
0.530 0.470 0.000
V70-V79 Bus occupant injured in transport accident
0.530 0.470 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.530 0.470 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.530 0.470 0.000
V40-V49 Car occupant injured in transport accident
0.530 0.470 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.530 0.470 0.000
V20-V29 Motorcycle rider injured in transport accident
0.530 0.470 0.000
V10-V19 Pedal cyclist injured in transport accident
0.530 0.470 0.000
V01-V09 Pedestrian injured in transport accident
0.530 0.470 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.530 0.470 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.529 0.471 0.000
N20.1 Calculus of ureter
0.528 0.472 0.000
L72.0 Epidermal cyst
0.528 0.472 0.000
N94.1 Dyspareunia
0.528 0.472 0.000
W00-W19 Falls
0.528 0.472 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.527 0.472 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.527 0.472 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.527 0.472 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.527 0.473 0.000
A00-A09 Intestinal infectious diseases
0.527 0.473 0.000
N80.1 Endometriosis of ovary
0.527 0.473 0.000
F10.0 Acute intoxication
0.526 0.474 0.000
N40 Hyperplasia of prostate
0.526 0.474 0.000
N39 Other disorders of urinary system
0.525 0.475 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.524 0.476 0.000
H05 Disorders of orbit
0.524 0.476 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.524 0.476 0.000
H02 Other disorders of eyelid
0.524 0.476 0.000
H01 Other inflammation of eyelid
0.524 0.476 0.000
H00 Hordeolum and chalazion
0.524 0.476 0.000
B25-B34 Other viral diseases
0.522 0.478 0.000
J34 Other disorders of nose and nasal sinuses
0.521 0.479 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.521 0.479 0.000
R06 Abnormalities of breathing
0.521 0.479 0.000
M15-M19 Arthrosis
0.521 0.479 0.000
R20 Disturbances of skin sensation
0.521 0.479 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.521 0.479 0.000
F30-F39 Mood [affective] disorders
0.520 0.480 0.000
B99-B99 Other infectious diseases
0.519 0.480 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.519 0.480 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.519 0.480 0.000
B65-B83 Helminthiases
0.519 0.480 0.000
B50-B64 Protozoal diseases
0.519 0.480 0.000
B35-B49 Mycoses
0.519 0.480 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.519 0.480 0.000
B15-B19 Viral hepatitis
0.519 0.480 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.519 0.480 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.519 0.480 0.000
A80-A89 Viral infections of the central nervous system
0.519 0.480 0.000
A75-A79 Rickettsioses
0.519 0.480 0.000
A70-A74 Other diseases caused by chlamydiae
0.519 0.480 0.000
A65-A69 Other spirochaetal diseases
0.519 0.480 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.519 0.480 0.000
A20-A28 Certain zoonotic bacterial diseases
0.519 0.480 0.000
A15-A19 Tuberculosis
0.519 0.480 0.000
N64 Other disorders of breast
0.519 0.480 0.000
N60 Benign mammary dysplasia
0.519 0.480 0.000
N62 Hypertrophy of breast
0.519 0.480 0.000
N61 Inflammatory disorders of breast
0.519 0.480 0.000
H90-H95 Other disorders of ear
0.519 0.481 0.000
J39 Other diseases of upper respiratory tract
0.518 0.482 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.518 0.482 0.000
J37 Chronic laryngitis and laryngotracheitis
0.518 0.482 0.000
J35 Chronic diseases of tonsils and adenoids
0.518 0.482 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.518 0.482 0.000
J30 Vasomotor and allergic rhinitis
0.518 0.482 0.000
J36 Peritonsillar abscess
0.518 0.482 0.000
S82 Fracture of lower leg, including ankle
0.517 0.482 0.000
J17 Pneumonia in diseases classified elsewhere
0.517 0.483 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.517 0.483 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.517 0.483 0.000
J12 Viral pneumonia, not elsewhere classified
0.517 0.483 0.000
J11 Influenza, virus not identified
0.517 0.483 0.000
J10 Influenza due to identified influenza virus
0.517 0.483 0.000
J14 Pneumonia due to Haemophilus influenzae
0.517 0.483 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.517 0.483 0.000
J09 Influenza due to certain identified influenza virus
0.517 0.483 0.000
R07.2 Precordial pain
0.517 0.483 0.000
R03.1 Nonspecific low blood-pressure reading
0.516 0.484 0.000
I45.9 Conduction disorder, unspecified
0.516 0.484 0.000
I45.8 Other specified conduction disorders
0.516 0.484 0.000
I45.6 Preexcitation syndrome
0.516 0.484 0.000
I45.5 Other specified heart block
0.516 0.484 0.000
I45.4 Nonspecific intraventricular block
0.516 0.484 0.000
I45.3 Trifascicular block
0.516 0.484 0.000
I45.2 Bifascicular block
0.516 0.484 0.000
I45.0 Right fascicular block
0.516 0.484 0.000
M49 Spondylopathies in diseases classified elsewhere
0.516 0.484 0.000
M46 Other inflammatory spondylopathies
0.516 0.484 0.000
M45 Ankylosing spondylitis
0.516 0.484 0.000
I44.7 Left bundle-branch block, unspecified
0.516 0.484 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.515 0.485 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.515 0.485 0.000
I47.1 Supraventricular tachycardia
0.515 0.485 0.000
I69 Sequelae of cerebrovascular disease
0.513 0.487 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.513 0.487 0.000
I67 Other cerebrovascular diseases
0.513 0.487 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.513 0.487 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.513 0.487 0.000
I62 Other nontraumatic intracranial haemorrhage
0.513 0.487 0.000
I60 Subarachnoid haemorrhage
0.513 0.487 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.513 0.487 0.000
R50-R69 General symptoms and signs
0.512 0.487 0.000
M20 Acquired deformities of fingers and toes
0.512 0.488 0.000
J18.1 Lobar pneumonia, unspecified
0.512 0.488 0.000
N93.0 Postcoital and contact bleeding
0.510 0.489 0.000
M23 Internal derangement of knee
0.510 0.490 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.509 0.491 0.000
N94.5 Secondary dysmenorrhoea
0.509 0.491 0.000
N94.4 Primary dysmenorrhoea
0.509 0.491 0.000
N94.3 Premenstrual tension syndrome
0.509 0.491 0.000
N94.2 Vaginismus
0.509 0.491 0.000
N94.0 Mittelschmerz
0.509 0.491 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.508 0.491 0.000
N92.5 Other specified irregular menstruation
0.507 0.492 0.000
N92.4 Excessive bleeding in the premenopausal period
0.507 0.492 0.000
N92.2 Excessive menstruation at puberty
0.507 0.492 0.000
H80-H83 Diseases of inner ear
0.507 0.492 0.000
H65-H75 Diseases of middle ear and mastoid
0.507 0.492 0.000
H60-H62 Diseases of external ear
0.507 0.492 0.000
R00 Abnormalities of heart beat
0.507 0.493 0.000
H42 Glaucoma in diseases classified elsewhere
0.507 0.493 0.000
N92.6 Irregular menstruation, unspecified
0.506 0.494 0.000
E50-E64 Other nutritional deficiencies
0.505 0.494 0.000
E40-E46 Malnutrition
0.505 0.494 0.000
E20-E35 Disorders of other endocrine glands
0.505 0.494 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.505 0.494 0.000
J18.9 Pneumonia, unspecified
0.505 0.495 0.000
F10.2 Dependence syndrome
0.504 0.496 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.503 0.497 0.000
N81 Female genital prolapse
0.502 0.498 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.502 0.498 0.000
I73 Other peripheral vascular diseases
0.502 0.498 0.000
M77 Other enthesopathies
0.502 0.498 0.000
M76 Enthesopathies of lower limb, excluding foot
0.502 0.498 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.502 0.498 0.000
M71 Other bursopathies
0.502 0.498 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.502 0.498 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.501 0.499 0.000
N87.1 Moderate cervical dysplasia
0.501 0.499 0.000
N87.0 Mild cervical dysplasia
0.501 0.499 0.000
N20.0 Calculus of kidney
0.501 0.499 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.500 0.499 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.500 0.500 0.000
I78 Diseases of capillaries
0.500 0.500 0.000
I77 Other disorders of arteries and arterioles
0.500 0.500 0.000
I74 Arterial embolism and thrombosis
0.500 0.500 0.000
I72 Other aneurysm
0.500 0.500 0.000
I71 Aortic aneurysm and dissection
0.500 0.500 0.000
I70 Atherosclerosis
0.500 0.500 0.000
J22 Unspecified acute lower respiratory infection
0.500 0.500 0.000
S59 Other and unspecified injuries of forearm
0.500 0.500 0.000
S58 Traumatic amputation of forearm
0.500 0.500 0.000
S57 Crushing injury of forearm
0.500 0.500 0.000
S56 Injury of muscle and tendon at forearm level
0.500 0.500 0.000
S55 Injury of blood vessels at forearm level
0.500 0.500 0.000
S54 Injury of nerves at forearm level
0.500 0.500 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.500 0.500 0.000
S51 Open wound of forearm
0.500 0.500 0.000
S50 Superficial injury of forearm
0.500 0.500 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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