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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs181715218
log Bayes Factor = 4.15927
Chromosome 10   position 81,185,314  (GRCh37) Explore rs181715218 on Ensembl!
Variant rs181715218 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
Chapter IX Diseases of the circulatory system
0.974 0.026 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.963 0.037 0.000
I20-I25 Ischaemic heart diseases
0.962 0.038 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.960 0.040 0.000
F17.1 Harmful use
0.945 0.055 0.000
Chapter VIII Diseases of the ear and mastoid process
0.944 0.056 0.000
S00 Superficial injury of head
0.944 0.056 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.940 0.060 0.000
S09 Other and unspecified injuries of head
0.934 0.066 0.000
I25 Chronic ischaemic heart disease
0.933 0.067 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.929 0.071 0.000
M45-M49 Spondylopathies
0.917 0.083 0.000
S00.8 Superficial injury of other parts of head
0.900 0.100 0.000
S09.9 Unspecified injury of head
0.889 0.111 0.000
R50-R69 General symptoms and signs
0.886 0.114 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.886 0.114 0.000
Chapter XX External causes of morbidity and mortality
0.883 0.117 0.000
Chapter VI Diseases of the nervous system
0.880 0.120 0.000
S01 Open wound of head
0.880 0.120 0.000
H90-H95 Other disorders of ear
0.877 0.123 0.000
M54 Dorsalgia
0.869 0.131 0.000
D50-D53 Nutritional anaemias
0.867 0.133 0.000
M51 Other intervertebral disk disorders
0.860 0.140 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.859 0.141 0.000
T66-T78 Other and unspecified effects of external causes
0.858 0.142 0.000
S50-S59 Injuries to the elbow and forearm
0.842 0.158 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.834 0.166 0.000
M70-M79 Other soft tissue disorders
0.829 0.171 0.000
H91 Other hearing loss
0.829 0.171 0.000
I25.1 Atherosclerotic heart disease
0.824 0.176 0.000
M48 Other spondylopathies
0.812 0.188 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.812 0.188 0.000
I22 Subsequent myocardial infarction
0.811 0.189 0.000
W00-W19 Falls
0.811 0.189 0.000
F17.2 Dependence syndrome
0.810 0.190 0.000
S70-S79 Injuries to the hip and thigh
0.809 0.191 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.807 0.193 0.000
S02 Fracture of skull and facial bones
0.807 0.193 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.806 0.194 0.000
M50 Cervical disk disorders
0.801 0.199 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.795 0.205 0.000
S60-S69 Injuries to the wrist and hand
0.795 0.205 0.000
H91.9 Hearing loss, unspecified
0.794 0.206 0.000
S06 Intracranial injury
0.792 0.208 0.000
F30-F39 Mood [affective] disorders
0.791 0.209 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.791 0.209 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.788 0.212 0.000
Chapter VII Diseases of the eye and adnexa
0.788 0.212 0.000
I20 Angina pectoris
0.787 0.213 0.000
M51.2 Other specified intervertebral disk displacement
0.786 0.214 0.000
M47 Spondylosis
0.784 0.216 0.000
I24 Other acute ischaemic heart diseases
0.772 0.228 0.000
D51 Vitamin B12 deficiency anaemia
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.233 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.766 0.234 0.000
M54.5 Low back pain
0.764 0.236 0.000
I60-I69 Cerebrovascular diseases
0.762 0.238 0.000
W19 Unspecified fall
0.760 0.240 0.000
S40-S49 Injuries to the shoulder and upper arm
0.760 0.240 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
T78 Adverse effects, not elsewhere classified
0.757 0.243 0.000
H65-H75 Diseases of middle ear and mastoid
0.754 0.246 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.748 0.252 0.000
R60 Oedema, not elsewhere classified
0.745 0.255 0.000
M15-M19 Arthrosis
0.737 0.263 0.000
M48.0 Spinal stenosis
0.736 0.264 0.000
R51 Headache
0.735 0.265 0.000
R52 Pain, not elsewhere classified
0.734 0.266 0.000
S52 Fracture of forearm
0.729 0.271 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.727 0.273 0.000
M54.59 Low back pain (Site unspecified)
0.726 0.274 0.000
M40-M43 Deforming dorsopathies
0.726 0.274 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.723 0.277 0.000
H80-H83 Diseases of inner ear
0.723 0.277 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.722 0.278 0.000
R21 Rash and other nonspecific skin eruption
0.721 0.279 0.000
R54 Senility
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I77 Other disorders of arteries and arterioles
0.717 0.283 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.286 0.000
S07 Crushing injury of head
0.714 0.286 0.000
S05 Injury of eye and orbit
0.714 0.286 0.000
S04 Injury of cranial nerves
0.714 0.286 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.286 0.000
D70 Agranulocytosis
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
S01.1 Open wound of eyelid and periocular area
0.711 0.289 0.000
R50 Fever of unknown origin
0.711 0.289 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.711 0.289 0.000
W19.9 Unspecified place
0.708 0.292 0.000
F99-F99 Unspecified mental disorder
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F80-F89 Disorders of psychological development
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
F60-F69 Disorders of adult personality and behaviour
0.707 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.707 0.293 0.000
R59 Enlarged lymph nodes
0.707 0.293 0.000
D50 Iron deficiency anaemia
0.705 0.295 0.000
Chapter I Certain infectious and parasitic diseases
0.704 0.296 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.702 0.298 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.699 0.301 0.000
S80-S89 Injuries to the knee and lower leg
0.698 0.302 0.000
I00-I02 Acute rheumatic fever
0.698 0.302 0.000
S00.0 Superficial injury of scalp
0.697 0.303 0.000
I25.2 Old myocardial infarction
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.697 0.303 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.697 0.303 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.697 0.303 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.697 0.303 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.697 0.303 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.697 0.303 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.697 0.303 0.000
F11 Mental and behavioural disorders due to use of opioids
0.697 0.303 0.000
M65-M68 Disorders of synovium and tendon
0.694 0.306 0.000
S00.9 Superficial injury of head, part unspecified
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.691 0.309 0.000
M20-M25 Other joint disorders
0.690 0.310 0.000
M54.6 Pain in thoracic spine
0.690 0.310 0.000
I23 Certain current complications following acute myocardial infarction
0.689 0.310 0.000
M05-M14 Inflammatory polyarthropathies
0.689 0.311 0.000
F17.9 Unspecified mental and behavioural disorder
0.688 0.311 0.000
F17.8 Other mental and behavioural disorders
0.688 0.311 0.000
F17.7 Residual and late-onset psychotic disorder
0.688 0.311 0.000
F17.6 Amnesic syndrome
0.688 0.311 0.000
F17.5 Psychotic disorder
0.688 0.311 0.000
F17.4 Withdrawal state with delirium
0.688 0.311 0.000
F17.3 Withdrawal state
0.688 0.311 0.000
F17.0 Acute intoxication
0.688 0.311 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.688 0.312 0.000
R63 Symptoms and signs concerning food and fluid intake
0.684 0.316 0.000
I30-I52 Other forms of heart disease
0.684 0.316 0.000
S20-S29 Injuries to the thorax
0.683 0.317 0.000
M54.2 Cervicalgia
0.683 0.317 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.681 0.319 0.000
I73 Other peripheral vascular diseases
0.680 0.320 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.320 0.000
S01.2 Open wound of nose
0.679 0.321 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.678 0.322 0.000
H60-H62 Diseases of external ear
0.677 0.323 0.000
S00.7 Multiple superficial injuries of head
0.677 0.323 0.000
S00.5 Superficial injury of lip and oral cavity
0.677 0.323 0.000
S00.4 Superficial injury of ear
0.677 0.323 0.000
S00.3 Superficial injury of nose
0.677 0.323 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.677 0.323 0.000
S00.1 Contusion of eyelid and periocular area
0.677 0.323 0.000
H92 Otalgia and effusion of ear
0.675 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.675 0.325 0.000
D80-D89 Certain disorders involving the immune mechanism
0.674 0.326 0.000
D55-D59 Haemolytic anaemias
0.674 0.326 0.000
S01.0 Open wound of scalp
0.673 0.327 0.000
G40-G47 Episodic and paroxysmal disorders
0.672 0.328 0.000
I05-I09 Chronic rheumatic heart diseases
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
M47.9 Spondylosis, unspecified
0.670 0.330 0.000
G20-G26 Extrapyramidal and movement disorders
0.670 0.330 0.000
S09.8 Other specified injuries of head
0.669 0.331 0.000
S09.7 Multiple injuries of head
0.669 0.331 0.000
S09.2 Traumatic rupture of ear drum
0.669 0.331 0.000
S09.1 Injury of muscle and tendon of head
0.669 0.331 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.669 0.331 0.000
I25.6 Silent myocardial ischaemia
0.669 0.331 0.000
I25.5 Ischaemic cardiomyopathy
0.669 0.331 0.000
I25.4 Coronary artery aneurysm
0.669 0.331 0.000
I25.3 Aneurysm of heart
0.669 0.331 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.669 0.331 0.000
D52 Folate deficiency anaemia
0.668 0.332 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.667 0.333 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.666 0.334 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.666 0.334 0.000
I71 Aortic aneurysm and dissection
0.664 0.336 0.000
R61 Hyperhidrosis
0.662 0.337 0.000
S01.8 Open wound of other parts of head
0.661 0.339 0.000
M49 Spondylopathies in diseases classified elsewhere
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.658 0.342 0.000
M45 Ankylosing spondylitis
0.658 0.342 0.000
M50.3 Other cervical disk degeneration
0.655 0.345 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.654 0.346 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.654 0.346 0.000
I20.9 Angina pectoris, unspecified
0.654 0.346 0.000
G30-G32 Other degenerative diseases of the nervous system
0.653 0.346 0.000
R20 Disturbances of skin sensation
0.653 0.347 0.000
S01.5 Open wound of lip and oral cavity
0.653 0.347 0.000
D60-D64 Aplastic and other anaemias
0.653 0.347 0.000
S01.9 Open wound of head, part unspecified
0.652 0.348 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.651 0.348 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.651 0.349 0.000
F20 Schizophrenia
0.651 0.349 0.000
M80-M85 Disorders of bone density and structure
0.648 0.352 0.000
M72 Fibroblastic disorders
0.648 0.352 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.647 0.353 0.000
S79 Other and unspecified injuries of hip and thigh
0.646 0.354 0.000
S06.0 Concussion
0.645 0.355 0.000
F32 Depressive episode
0.645 0.355 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.645 0.355 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.644 0.356 0.000
R60.0 Localised oedema
0.644 0.356 0.000
M54.3 Sciatica
0.640 0.360 0.000
S02.4 Fracture of malar and maxillary bones
0.637 0.363 0.000
H53-H54 Visual disturbances and blindness
0.636 0.364 0.000
R68 Other general symptoms and signs
0.635 0.365 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.635 0.365 0.000
R62 Lack of expected normal physiological development
0.635 0.365 0.000
R57 Shock, not elsewhere classified
0.635 0.365 0.000
R64 Cachexia
0.635 0.365 0.000
R58 Haemorrhage, not elsewhere classified
0.635 0.365 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.635 0.365 0.000
I21 Acute myocardial infarction
0.634 0.366 0.000
T78.2 Anaphylactic shock, unspecified
0.634 0.366 0.000
S02.6 Fracture of mandible
0.633 0.367 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.633 0.367 0.000
Y35-Y36 Legal intervention and operations of war
0.633 0.367 0.000
Y10-Y34 Event of undetermined intent
0.633 0.367 0.000
Y00-Y09 Assault
0.633 0.367 0.000
X85-X99 Assault
0.633 0.367 0.000
X60-X84 Intentional self-harm
0.633 0.367 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.633 0.367 0.000
X50-X57 Overexertion, travel and privation
0.633 0.367 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.633 0.367 0.000
X30-X39 Exposure to forces of nature
0.633 0.367 0.000
X20-X29 Contact with venomous animals and plants
0.633 0.367 0.000
X10-X19 Contact with heat and hot substances
0.633 0.367 0.000
X00-X09 Exposure to smoke, fire and flames
0.633 0.367 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.633 0.367 0.000
W75-W84 Other accidental threats to breathing
0.633 0.367 0.000
W65-W74 Accidental drowning and submersion
0.633 0.367 0.000
W50-W64 Exposure to animate mechanical forces
0.633 0.367 0.000
V98-V99 Other and unspecified transport accidents
0.633 0.367 0.000
V95-V97 Air and space transport accidents
0.633 0.367 0.000
V90-V94 Water transport accidents
0.633 0.367 0.000
V80-V89 Other land transport accidents
0.633 0.367 0.000
V70-V79 Bus occupant injured in transport accident
0.633 0.367 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.633 0.367 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.633 0.367 0.000
V40-V49 Car occupant injured in transport accident
0.633 0.367 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.633 0.367 0.000
V20-V29 Motorcycle rider injured in transport accident
0.633 0.367 0.000
V01-V09 Pedestrian injured in transport accident
0.633 0.367 0.000
W20-W49 Exposure to inanimate mechanical forces
0.633 0.367 0.000
G70-G73 Diseases of myoneural junction and muscle
0.631 0.369 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.631 0.369 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.631 0.369 0.000
I45 Other conduction disorders
0.631 0.369 0.000
S01.7 Multiple open wounds of head
0.631 0.369 0.000
S01.4 Open wound of cheek and temporomandibular area
0.631 0.369 0.000
S01.3 Open wound of ear
0.631 0.369 0.000
T78.4 Allergy, unspecified
0.630 0.370 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.629 0.371 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.629 0.371 0.000
H90 Conductive and sensorineural hearing loss
0.629 0.371 0.000
M79.6 Pain in limb
0.629 0.371 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.628 0.372 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.627 0.372 0.000
M47.1 Other spondylosis with myelopathy
0.626 0.373 0.000
M54.1 Radiculopathy
0.625 0.375 0.000
I74 Arterial embolism and thrombosis
0.625 0.375 0.000
M48.02 Spinal stenosis (Cervical region)
0.624 0.376 0.000
R55 Syncope and collapse
0.623 0.377 0.000
M54.8 Other dorsalgia
0.623 0.377 0.000
M54.4 Lumbago with sciatica
0.623 0.377 0.000
M54.0 Panniculitis affecting regions of neck and back
0.623 0.377 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.622 0.378 0.000
D53 Other nutritional anaemias
0.622 0.378 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.620 0.380 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.619 0.381 0.000
S52.1 Fracture of upper end of radius
0.618 0.382 0.000
S72 Fracture of femur
0.617 0.383 0.000
M51.3 Other specified intervertebral disk degeneration
0.617 0.383 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.617 0.383 0.000
M51.9 Intervertebral disk disorder, unspecified
0.617 0.383 0.000
M51.8 Other specified intervertebral disk disorders
0.617 0.383 0.000
M51.4 Schmorl's nodes
0.617 0.383 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.617 0.383 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.616 0.384 0.000
I78 Diseases of capillaries
0.616 0.384 0.000
I72 Other aneurysm
0.616 0.384 0.000
I70 Atherosclerosis
0.616 0.384 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.616 0.384 0.000
F10.1 Harmful use
0.616 0.384 0.000
H65 Nonsuppurative otitis media
0.615 0.385 0.000
T75 Effects of other external causes
0.615 0.385 0.000
T74 Maltreatment syndromes
0.615 0.385 0.000
T73 Effects of other deprivation
0.615 0.385 0.000
T70 Effects of air pressure and water pressure
0.615 0.385 0.000
T69 Other effects of reduced temperature
0.615 0.385 0.000
T67 Effects of heat and light
0.615 0.385 0.000
T71 Asphyxiation
0.615 0.385 0.000
T68 Hypothermia
0.615 0.385 0.000
T66 Unspecified effects of radiation
0.615 0.385 0.000
S60 Superficial injury of wrist and hand
0.615 0.385 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.614 0.386 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.613 0.387 0.000
I20.8 Other forms of angina pectoris
0.612 0.388 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.612 0.388 0.000
M50.2 Other cervical disk displacement
0.611 0.389 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.611 0.389 0.000
S32 Fracture of lumbar spine and pelvis
0.610 0.390 0.000
G90-G99 Other disorders of the nervous system
0.609 0.390 0.000
I60 Subarachnoid haemorrhage
0.609 0.391 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.609 0.391 0.000
W19.4 Street and highway
0.607 0.393 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.606 0.394 0.000
S59 Other and unspecified injuries of forearm
0.604 0.396 0.000
S58 Traumatic amputation of forearm
0.604 0.396 0.000
S57 Crushing injury of forearm
0.604 0.396 0.000
S56 Injury of muscle and tendon at forearm level
0.604 0.396 0.000
S55 Injury of blood vessels at forearm level
0.604 0.396 0.000
S54 Injury of nerves at forearm level
0.604 0.396 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.604 0.396 0.000
S51 Open wound of forearm
0.604 0.396 0.000
S50 Superficial injury of forearm
0.604 0.396 0.000
M79.8 Other specified soft tissue disorders
0.601 0.398 0.000
H25-H28 Disorders of lens
0.601 0.399 0.000
R52.1 Chronic intractable pain
0.601 0.399 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.600 0.400 0.000
Q50-Q56 Congenital malformations of genital organs
0.599 0.400 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.599 0.401 0.000
R23 Other skin changes
0.598 0.402 0.000
S42 Fracture of shoulder and upper arm
0.595 0.405 0.000
M77 Other enthesopathies
0.594 0.406 0.000
M76 Enthesopathies of lower limb, excluding foot
0.594 0.406 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.594 0.406 0.000
M71 Other bursopathies
0.594 0.406 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.594 0.406 0.000
H91.8 Other specified hearing loss
0.594 0.406 0.000
H91.3 Deaf mutism, not elsewhere classified
0.594 0.406 0.000
H91.2 Sudden idiopathic hearing loss
0.594 0.406 0.000
H91.1 Presbycusis
0.594 0.406 0.000
H91.0 Ototoxic hearing loss
0.594 0.406 0.000
D50.8 Other iron deficiency anaemias
0.591 0.408 0.000
S61 Open wound of wrist and hand
0.591 0.409 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.590 0.410 0.000
G56 Mononeuropathies of upper limb
0.590 0.410 0.000
M50.1 Cervical disk disorder with radiculopathy
0.590 0.410 0.000
M89 Other disorders of bone
0.588 0.412 0.000
S62 Fracture at wrist and hand level
0.588 0.412 0.000
I49 Other cardiac arrhythmias
0.587 0.413 0.000
R50.9 Fever, unspecified
0.586 0.414 0.000
S52.5 Fracture of lower end of radius
0.584 0.416 0.000
M25 Other joint disorders, not elsewhere classified
0.584 0.416 0.000
R47-R49 Symptoms and signs involving speech and voice
0.583 0.417 0.000
M48.9 Spondylopathy, unspecified
0.582 0.418 0.000
M48.8 Other specified spondylopathies
0.582 0.418 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.582 0.418 0.000
M48.4 Fatigue fracture of vertebra
0.582 0.418 0.000
M48.3 Traumatic spondylopathy
0.582 0.418 0.000
M48.2 Kissing spine
0.582 0.418 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.582 0.418 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.582 0.418 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.582 0.418 0.000
I22.8 Subsequent myocardial infarction of other sites
0.582 0.418 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.582 0.418 0.000
W18 Other fall on same level
0.582 0.418 0.000
W17 Other fall from one level to another
0.582 0.418 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.582 0.418 0.000
W15 Fall from cliff
0.582 0.418 0.000
W14 Fall from tree
0.582 0.418 0.000
W13 Fall from, out of or through building or structure
0.582 0.418 0.000
W12 Fall on and from scaffolding
0.582 0.418 0.000
W11 Fall on and from ladder
0.582 0.418 0.000
W10 Fall on and from stairs and steps
0.582 0.418 0.000
W09 Fall involving playground equipment
0.582 0.418 0.000
W08 Fall involving other furniture
0.582 0.418 0.000
W07 Fall involving chair
0.582 0.418 0.000
W06 Fall involving bed
0.582 0.418 0.000
W05 Fall involving wheelchair
0.582 0.418 0.000
W04 Fall while being carried or supported by other persons
0.582 0.418 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.582 0.418 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.582 0.418 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.582 0.418 0.000
W00 Fall on same level involving ice and snow
0.582 0.418 0.000
H52 Disorders of refraction and accommodation
0.581 0.419 0.000
S78 Traumatic amputation of hip and thigh
0.580 0.420 0.000
S77 Crushing injury of hip and thigh
0.580 0.420 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.580 0.420 0.000
S75 Injury of blood vessels at hip and thigh level
0.580 0.420 0.000
S74 Injury of nerves at hip and thigh level
0.580 0.420 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.580 0.420 0.000
S71 Open wound of hip and thigh
0.580 0.420 0.000
S70 Superficial injury of hip and thigh
0.580 0.420 0.000
I77.1 Stricture of artery
0.580 0.420 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.579 0.421 0.000
D75 Other diseases of blood and blood-forming organs
0.579 0.421 0.000
D74 Methaemoglobinaemia
0.579 0.421 0.000
D73 Diseases of spleen
0.579 0.421 0.000
D72 Other disorders of white blood cells
0.579 0.421 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.579 0.421 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.579 0.421 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.579 0.421 0.000
S02.8 Fractures of other skull and facial bones
0.579 0.421 0.000
S02.7 Multiple fractures involving skull and facial bones
0.579 0.421 0.000
S02.5 Fracture of tooth
0.579 0.421 0.000
S02.3 Fracture of orbital floor
0.579 0.421 0.000
S02.1 Fracture of base of skull
0.579 0.421 0.000
S02.0 Fracture of vault of skull
0.579 0.421 0.000
M48.06 Spinal stenosis (Lumbar region)
0.578 0.422 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.578 0.422 0.000
T87 Complications peculiar to reattachment and amputation
0.578 0.422 0.000
T86 Failure and rejection of transplanted organs and tissues
0.578 0.422 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.578 0.422 0.000
F31 Bipolar affective disorder
0.577 0.423 0.000
H43-H45 Disorders of vitreous body and globe
0.576 0.424 0.000
G40 Epilepsy
0.576 0.424 0.000
I63 Cerebral infarction
0.575 0.425 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.575 0.425 0.000
M50.9 Cervical disk disorder, unspecified
0.574 0.426 0.000
M50.8 Other cervical disk disorders
0.574 0.426 0.000
H93 Other disorders of ear, not elsewhere classified
0.572 0.427 0.000
M48.09 Spinal stenosis (Site unspecified)
0.573 0.427 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.570 0.430 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.570 0.430 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.570 0.430 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.570 0.430 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.570 0.430 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.570 0.430 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.570 0.430 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.570 0.430 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.570 0.430 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.570 0.430 0.000
T36 Poisoning by systemic antibiotics
0.570 0.430 0.000
M50.0 Cervical disk disorder with myelopathy
0.570 0.430 0.000
S69 Other and unspecified injuries of wrist and hand
0.570 0.430 0.000
S68 Traumatic amputation of wrist and hand
0.570 0.430 0.000
S67 Crushing injury of wrist and hand
0.570 0.430 0.000
S65 Injury of blood vessels at wrist and hand level
0.570 0.430 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.570 0.430 0.000
S02.2 Fracture of nasal bones
0.568 0.431 0.000
S64 Injury of nerves at wrist and hand level
0.568 0.432 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.568 0.432 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.568 0.432 0.000
S06.9 Intracranial injury, unspecified
0.568 0.432 0.000
S06.8 Other intracranial injuries
0.568 0.432 0.000
S06.7 Intracranial injury with prolonged coma
0.568 0.432 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.568 0.432 0.000
S06.5 Traumatic subdural haemorrhage
0.568 0.432 0.000
S06.4 Epidural haemorrhage
0.568 0.432 0.000
S06.3 Focal brain injury
0.568 0.432 0.000
S06.2 Diffuse brain injury
0.568 0.432 0.000
S06.1 Traumatic cerebral oedema
0.568 0.432 0.000
I10-I15 Hypertensive diseases
0.568 0.432 0.000
F38 Other mood [affective] disorders
0.567 0.433 0.000
F34 Persistent mood [affective] disorders
0.567 0.433 0.000
F33 Recurrent depressive disorder
0.567 0.433 0.000
F30 Manic episode
0.567 0.433 0.000
F39 Unspecified mood [affective] disorder
0.567 0.433 0.000
F25 Schizoaffective disorders
0.567 0.433 0.000
F23 Acute and transient psychotic disorders
0.567 0.433 0.000
F22 Persistent delusional disorders
0.567 0.433 0.000
F29 Unspecified nonorganic psychosis
0.567 0.433 0.000
F28 Other nonorganic psychotic disorders
0.567 0.433 0.000
F24 Induced delusional disorder
0.567 0.433 0.000
F21 Schizotypal disorder
0.567 0.433 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.565 0.435 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.565 0.435 0.000
S37 Injury of urinary and pelvic organs
0.565 0.435 0.000
S36 Injury of intra-abdominal organs
0.565 0.435 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.565 0.435 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.565 0.435 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.565 0.435 0.000
S31 Open wound of abdomen, lower back and pelvis
0.565 0.435 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.565 0.435 0.000
H55-H59 Other disorders of eye and adnexa
0.565 0.435 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.565 0.435 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.565 0.435 0.000
H10-H13 Disorders of conjunctiva
0.565 0.435 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.565 0.435 0.000
I20.1 Angina pectoris with documented spasm
0.564 0.436 0.000
I73.9 Peripheral vascular disease, unspecified
0.563 0.437 0.000
R52.2 Other chronic pain
0.563 0.437 0.000
S81 Open wound of lower leg
0.563 0.437 0.000
R26 Abnormalities of gait and mobility
0.563 0.437 0.000
M47.2 Other spondylosis with radiculopathy
0.562 0.438 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.562 0.438 0.000
H81 Disorders of vestibular function
0.561 0.438 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.561 0.439 0.000
H30-H36 Disorders of choroid and retina
0.561 0.439 0.000
I67 Other cerebrovascular diseases
0.561 0.439 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.560 0.440 0.000
M17 Gonarthrosis [arthrosis of knee]
0.560 0.440 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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