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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs182503338
log Bayes Factor = 4.85679
Chromosome 6   position 34,582,274  (GRCh37) Explore rs182503338 on Ensembl!
Variant rs182503338 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N20-N23 Urolithiasis
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
N20 Calculus of kidney and ureter
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.965 0.035 0.000
N17-N19 Renal failure
0.964 0.036 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.940 0.060 0.000
R20 Disturbances of skin sensation
0.940 0.060 0.000
N20.0 Calculus of kidney
0.937 0.063 0.000
N20.1 Calculus of ureter
0.930 0.070 0.000
N18 Chronic renal failure
0.927 0.073 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.921 0.079 0.000
Chapter VII Diseases of the eye and adnexa
0.920 0.080 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.912 0.088 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.909 0.091 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.907 0.093 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.905 0.095 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.898 0.102 0.000
M80-M85 Disorders of bone density and structure
0.891 0.109 0.000
N18.3 Chronic kidney disease, stage 3
0.891 0.109 0.000
N10-N16 Renal tubulo-interstitial diseases
0.869 0.131 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.868 0.132 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.861 0.139 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.859 0.141 0.000
M20-M25 Other joint disorders
0.852 0.148 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.852 0.148 0.000
N30-N39 Other diseases of urinary system
0.850 0.150 0.000
Y83.8 Other surgical procedures
0.843 0.157 0.000
L40-L45 Papulosquamous disorders
0.828 0.172 0.000
R07 Pain in throat and chest
0.827 0.173 0.000
R20.2 Paraesthesia of skin
0.823 0.177 0.000
M47 Spondylosis
0.821 0.179 0.000
M81 Osteoporosis without pathological fracture
0.819 0.181 0.000
R47-R49 Symptoms and signs involving speech and voice
0.818 0.182 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.813 0.187 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.809 0.191 0.000
N00-N08 Glomerular diseases
0.809 0.191 0.000
O36 Maternal care for other known or suspected foetal problems
0.808 0.192 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.808 0.192 0.000
N80 Endometriosis
0.808 0.192 0.000
M48 Other spondylopathies
0.806 0.194 0.000
N23 Unspecified renal colic
0.805 0.195 0.000
Y83.6 Removal of other organ (partial) (total)
0.804 0.196 0.000
M46 Other inflammatory spondylopathies
0.803 0.197 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.803 0.197 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.802 0.198 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
N13 Obstructive and reflux uropathy
0.794 0.206 0.000
G40-G47 Episodic and paroxysmal disorders
0.791 0.209 0.000
R07.3 Other chest pain
0.788 0.212 0.000
H30-H36 Disorders of choroid and retina
0.788 0.212 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.785 0.215 0.000
N17 Acute renal failure
0.782 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
N21 Calculus of lower urinary tract
0.778 0.222 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.775 0.225 0.000
H40-H42 Glaucoma
0.773 0.227 0.000
M81.9 Osteoporosis, unspecified
0.768 0.232 0.000
L40 Psoriasis
0.768 0.232 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.767 0.233 0.000
M91-M94 Chondropathies
0.767 0.233 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.765 0.235 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.763 0.237 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.758 0.242 0.000
N20.2 Calculus of kidney with calculus of ureter
0.757 0.243 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.753 0.247 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.749 0.251 0.000
N80.3 Endometriosis of pelvic peritoneum
0.745 0.255 0.000
H55-H59 Other disorders of eye and adnexa
0.743 0.257 0.000
Chapter VIII Diseases of the ear and mastoid process
0.742 0.258 0.000
N60-N64 Disorders of breast
0.741 0.259 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.262 0.000
N18.9 Chronic renal failure, unspecified
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.736 0.263 0.000
N99-N99 Other disorders of the genitourinary system
0.736 0.264 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
N39 Other disorders of urinary system
0.731 0.269 0.000
M47.9 Spondylosis, unspecified
0.730 0.270 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.730 0.270 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.728 0.272 0.000
N97 Female infertility
0.728 0.272 0.000
M25 Other joint disorders, not elsewhere classified
0.726 0.274 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.726 0.274 0.000
L40.9 Psoriasis, unspecified
0.723 0.277 0.000
N72 Inflammatory disease of cervix uteri
0.722 0.278 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.721 0.279 0.000
H33 Retinal detachments and breaks
0.718 0.282 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.717 0.283 0.000
R06 Abnormalities of breathing
0.715 0.285 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
H53-H54 Visual disturbances and blindness
0.707 0.292 0.000
M48.0 Spinal stenosis
0.705 0.295 0.000
G20-G26 Extrapyramidal and movement disorders
0.705 0.295 0.000
S80-S89 Injuries to the knee and lower leg
0.705 0.295 0.000
N20.9 Urinary calculus, unspecified
0.705 0.295 0.000
M45 Ankylosing spondylitis
0.704 0.295 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
R01 Cardiac murmurs and other cardiac sounds
0.702 0.298 0.000
Chapter V Mental and behavioural disorders
0.702 0.298 0.000
O80-O84 Delivery
0.701 0.299 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.700 0.300 0.000
G30-G32 Other degenerative diseases of the nervous system
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X60-X84 Intentional self-harm
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
W20-W49 Exposure to inanimate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V80-V89 Other land transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V20-V29 Motorcycle rider injured in transport accident
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
H10-H13 Disorders of conjunctiva
0.699 0.301 0.000
M50-M54 Other dorsopathies
0.698 0.302 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.692 0.308 0.000
R23 Other skin changes
0.692 0.308 0.000
O36.9 Maternal care for foetal problem, unspecified
0.690 0.310 0.000
R05 Cough
0.690 0.310 0.000
M15-M19 Arthrosis
0.689 0.310 0.000
M70-M79 Other soft tissue disorders
0.689 0.311 0.000
R21 Rash and other nonspecific skin eruption
0.688 0.312 0.000
M05-M14 Inflammatory polyarthropathies
0.687 0.313 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.681 0.319 0.000
N73 Other female pelvic inflammatory diseases
0.680 0.319 0.000
N25-N29 Other disorders of kidney and ureter
0.680 0.320 0.000
G40 Epilepsy
0.679 0.321 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.679 0.321 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.679 0.321 0.000
M49 Spondylopathies in diseases classified elsewhere
0.679 0.321 0.000
N19 Unspecified renal failure
0.677 0.323 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
R20.3 Hyperaesthesia
0.674 0.326 0.000
R20.1 Hypoaesthesia of skin
0.674 0.326 0.000
R20.0 Anaesthesia of skin
0.674 0.326 0.000
Y84.2 Radiological procedure and radiotherapy
0.673 0.327 0.000
O30 Multiple gestation
0.671 0.329 0.000
N80.1 Endometriosis of ovary
0.671 0.329 0.000
O36.5 Maternal care for poor foetal growth
0.671 0.329 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.670 0.330 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.670 0.330 0.000
H43-H45 Disorders of vitreous body and globe
0.669 0.331 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.668 0.331 0.000
H40 Glaucoma
0.668 0.332 0.000
Chapter I Certain infectious and parasitic diseases
0.667 0.333 0.000
N86 Erosion and ectropion of cervix uteri
0.666 0.334 0.000
R94 Abnormal results of function studies
0.665 0.335 0.000
N18.8 Other chronic renal failure
0.665 0.335 0.000
N18.5 Chronic kidney disease, stage 5
0.665 0.335 0.000
N18.4 Chronic kidney disease, stage 4
0.665 0.335 0.000
N18.2 Chronic kidney disease, stage 2
0.665 0.335 0.000
N18.1 Chronic kidney disease, stage 1
0.665 0.335 0.000
N18.0 End-stage renal disease
0.665 0.335 0.000
N30 Cystitis
0.664 0.336 0.000
G93 Other disorders of brain
0.662 0.338 0.000
R47 Speech disturbances, not elsewhere classified
0.662 0.338 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.660 0.340 0.000
N75 Diseases of Bartholin's gland
0.660 0.340 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.659 0.341 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.659 0.341 0.000
Y83.3 Surgical operation with formation of external stoma
0.657 0.343 0.000
M20 Acquired deformities of fingers and toes
0.656 0.344 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.656 0.344 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.655 0.345 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.655 0.345 0.000
M31 Other necrotising vasculopathies
0.654 0.346 0.000
L10-L14 Bullous disorders
0.654 0.346 0.000
W00-W19 Falls
0.653 0.347 0.000
N17.9 Acute renal failure, unspecified
0.652 0.348 0.000
R02 Gangrene, not elsewhere classified
0.651 0.348 0.000
R04 Haemorrhage from respiratory passages
0.651 0.349 0.000
O85-O92 Complications predominantly related to the puerperium
0.650 0.349 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.650 0.350 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.350 0.000
Y83.9 Surgical procedure, unspecified
0.649 0.351 0.000
Y83.5 Amputation of limb(s)
0.649 0.351 0.000
Y83.0 Surgical operation with transplant of whole organ
0.649 0.351 0.000
Y40 Systemic antibiotics
0.645 0.355 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.644 0.356 0.000
N32 Other disorders of bladder
0.644 0.356 0.000
T66-T78 Other and unspecified effects of external causes
0.643 0.356 0.000
T81 Complications of procedures, not elsewhere classified
0.643 0.357 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.642 0.358 0.000
N80.9 Endometriosis, unspecified
0.642 0.358 0.000
L50-L54 Urticaria and erythema
0.642 0.358 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.641 0.359 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.640 0.360 0.000
M85 Other disorders of bone density and structure
0.639 0.361 0.000
M84 Disorders of continuity of bone
0.639 0.361 0.000
M83 Adult osteomalacia
0.639 0.361 0.000
M82 Osteoporosis in diseases classified elsewhere
0.639 0.361 0.000
M80 Osteoporosis with pathological fracture
0.639 0.361 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.639 0.361 0.000
M17 Gonarthrosis [arthrosis of knee]
0.636 0.364 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.635 0.365 0.000
R27 Other lack of coordination
0.635 0.365 0.000
N39.4 Other specified urinary incontinence
0.634 0.366 0.000
Y57 Other and unspecified drugs and medicaments
0.633 0.366 0.000
S50-S59 Injuries to the elbow and forearm
0.633 0.367 0.000
N97.9 Female infertility, unspecified
0.633 0.367 0.000
R49 Voice disturbances
0.633 0.367 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.632 0.368 0.000
N03 Chronic nephritic syndrome
0.632 0.368 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.632 0.368 0.000
G37 Other demyelinating diseases of central nervous system
0.632 0.368 0.000
N02 Recurrent and persistent haematuria
0.631 0.368 0.000
N87 Dysplasia of cervix uteri
0.631 0.369 0.000
N36 Other disorders of urethra
0.630 0.370 0.000
O36.8 Maternal care for other specified foetal problems
0.629 0.371 0.000
N89 Other noninflammatory disorders of vagina
0.629 0.371 0.000
S20-S29 Injuries to the thorax
0.628 0.372 0.000
O00-O08 Pregnancy with abortive outcome
0.627 0.372 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.627 0.373 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.625 0.375 0.000
N21.0 Calculus in bladder
0.624 0.376 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.624 0.376 0.000
M35 Other systemic involvement of connective tissue
0.624 0.376 0.000
G35 Multiple sclerosis
0.623 0.376 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.623 0.377 0.000
N15 Other renal tubulo-interstitial diseases
0.623 0.377 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.623 0.377 0.000
N11 Chronic tubulo-interstitial nephritis
0.623 0.377 0.000
N10 Acute tubulo-interstitial nephritis
0.623 0.377 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.622 0.377 0.000
N76 Other inflammation of vagina and vulva
0.622 0.377 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.622 0.377 0.000
N71 Inflammatory disease of uterus, except cervix
0.622 0.377 0.000
N70 Salpingitis and oophoritis
0.622 0.377 0.000
L05 Pilonidal cyst
0.621 0.379 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.620 0.380 0.000
Chapter IX Diseases of the circulatory system
0.619 0.381 0.000
N98 Complications associated with artificial fertilisation
0.617 0.383 0.000
N91 Absent, scanty and rare menstruation
0.617 0.383 0.000
N82 Fistulae involving female genital tract
0.617 0.383 0.000
N96 Habitual aborter
0.617 0.383 0.000
H57 Other disorders of eye and adnexa
0.617 0.383 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.617 0.383 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.617 0.383 0.000
L90 Atrophic disorders of skin
0.617 0.383 0.000
T79-T79 Certain early complications of trauma
0.616 0.384 0.000
T33-T35 Frostbite
0.616 0.384 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.616 0.384 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.616 0.384 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.616 0.384 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.616 0.384 0.000
T00-T07 Injuries involving multiple body regions
0.616 0.384 0.000
S90-S99 Injuries to the ankle and foot
0.616 0.384 0.000
S10-S19 Injuries to the neck
0.616 0.384 0.000
N39.9 Disorder of urinary system, unspecified
0.612 0.388 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.611 0.389 0.000
M34 Systemic sclerosis
0.611 0.389 0.000
M33 Dermatopolymyositis
0.611 0.389 0.000
M32 Systemic lupus erythematosus
0.611 0.389 0.000
M30 Polyarteritis nodosa and related conditions
0.611 0.389 0.000
M22 Disorders of patella
0.611 0.389 0.000
M21 Other acquired deformities of limbs
0.611 0.389 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.610 0.389 0.000
O45 Premature separation of placenta [abruptio placentae]
0.610 0.389 0.000
O44 Placenta praevia
0.610 0.389 0.000
O43 Placental disorders
0.610 0.389 0.000
O41 Other disorders of amniotic fluid and membranes
0.610 0.389 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.610 0.389 0.000
O33 Maternal care for known or suspected disproportion
0.610 0.389 0.000
O31 Complications specific to multiple gestation
0.610 0.389 0.000
O40 Polyhydramnios
0.610 0.389 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.611 0.389 0.000
M81.98 Osteoporosis, unspecified (Other)
0.610 0.390 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.610 0.390 0.000
N37 Urethral disorders in diseases classified elsewhere
0.610 0.390 0.000
N34 Urethritis and urethral syndrome
0.610 0.390 0.000
N33 Bladder disorders in diseases classified elsewhere
0.610 0.390 0.000
N60 Benign mammary dysplasia
0.608 0.392 0.000
L20-L30 Dermatitis and eczema
0.607 0.393 0.000
L60-L75 Disorders of skin appendages
0.607 0.393 0.000
N92 Excessive, frequent and irregular menstruation
0.607 0.393 0.000
G91 Hydrocephalus
0.607 0.393 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.606 0.394 0.000
M94 Other disorders of cartilage
0.606 0.394 0.000
H33.2 Serous retinal detachment
0.606 0.394 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.605 0.394 0.000
G47 Sleep disorders
0.604 0.396 0.000
Y84.6 Urinary catheterisation
0.604 0.396 0.000
R06.5 Mouth breathing
0.604 0.396 0.000
N90.5 Atrophy of vulva
0.601 0.399 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.601 0.399 0.000
N39.0 Urinary tract infection, site not specified
0.601 0.399 0.000
R80 Isolated proteinuria
0.600 0.400 0.000
G40.9 Epilepsy, unspecified
0.599 0.401 0.000
N13.3 Other and unspecified hydronephrosis
0.599 0.401 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.599 0.401 0.000
M25.5 Pain in joint
0.598 0.402 0.000
R26 Abnormalities of gait and mobility
0.598 0.402 0.000
H35 Other retinal disorders
0.598 0.402 0.000
S82 Fracture of lower leg, including ankle
0.594 0.406 0.000
L44 Other papulosquamous disorders
0.594 0.406 0.000
L43 Lichen planus
0.594 0.406 0.000
L41 Parapsoriasis
0.594 0.406 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.594 0.406 0.000
L42 Pityriasis rosea
0.594 0.406 0.000
M47.8 Other spondylosis
0.593 0.407 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.593 0.407 0.000
L03 Cellulitis
0.593 0.407 0.000
R07.1 Chest pain on breathing
0.593 0.407 0.000
R07.0 Pain in throat
0.593 0.407 0.000
G70 Myasthenia gravis and other myoneural disorders
0.592 0.408 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.592 0.408 0.000
M17.9 Gonarthrosis, unspecified
0.591 0.409 0.000
N90.7 Vulvar cyst
0.590 0.409 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.590 0.410 0.000
H33.0 Retinal detachment with retinal break
0.590 0.410 0.000
M24 Other specific joint derangements
0.590 0.410 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.590 0.410 0.000
M47.2 Other spondylosis with radiculopathy
0.589 0.411 0.000
M47.1 Other spondylosis with myelopathy
0.589 0.411 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.589 0.411 0.000
Y84.8 Other medical procedures
0.589 0.411 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.588 0.412 0.000
R25 Abnormal involuntary movements
0.588 0.412 0.000
M81.8 Other osteoporosis
0.587 0.412 0.000
M81.6 Localised osteoporosis [Lequesne]
0.587 0.412 0.000
M81.5 Idiopathic osteoporosis
0.587 0.412 0.000
M81.4 Drug-induced osteoporosis
0.587 0.412 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.587 0.412 0.000
M81.2 Osteoporosis of disuse
0.587 0.412 0.000
M81.1 Postoophorectomy osteoporosis
0.587 0.412 0.000
M81.0 Postmenopausal osteoporosis
0.587 0.412 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.586 0.414 0.000
R30-R39 Symptoms and signs involving the urinary system
0.586 0.414 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.586 0.414 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.586 0.414 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.586 0.414 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.585 0.415 0.000
O47 False labour
0.585 0.415 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.585 0.415 0.000
H33.5 Other retinal detachments
0.584 0.416 0.000
M48.06 Spinal stenosis (Lumbar region)
0.584 0.416 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.584 0.416 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.583 0.417 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.583 0.417 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.583 0.417 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.583 0.417 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.583 0.417 0.000
R47.0 Dysphasia and aphasia
0.583 0.417 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.582 0.418 0.000
Y84.0 Cardiac catheterisation
0.582 0.418 0.000
O42 Premature rupture of membranes
0.580 0.420 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.580 0.420 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.580 0.420 0.000
N06 Isolated proteinuria with specified morphological lesion
0.580 0.420 0.000
N05 Unspecified nephritic syndrome
0.580 0.420 0.000
N04 Nephrotic syndrome
0.580 0.420 0.000
N01 Rapidly progressive nephritic syndrome
0.580 0.420 0.000
N00 Acute nephritic syndrome
0.580 0.420 0.000
S70-S79 Injuries to the hip and thigh
0.580 0.420 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.579 0.421 0.000
O36.6 Maternal care for excessive foetal growth
0.579 0.421 0.000
O36.4 Maternal care for intra-uterine death
0.579 0.421 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.579 0.421 0.000
O36.2 Maternal care for hydrops foetalis
0.579 0.421 0.000
O36.1 Maternal care for other isoimmunisation
0.579 0.421 0.000
Y59 Other and unspecified vaccines and biological substances
0.579 0.421 0.000
Y58 Bacterial vaccines
0.579 0.421 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.579 0.421 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.579 0.421 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.579 0.421 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.579 0.421 0.000
Y52 Agents primarily affecting the cardiovascular system
0.579 0.421 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.579 0.421 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.579 0.421 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.579 0.421 0.000
Y48 Anaesthetics and therapeutic gases
0.579 0.421 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.579 0.421 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.579 0.421 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.579 0.421 0.000
Y44 Agents primarily affecting blood constituents
0.579 0.421 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.579 0.421 0.000
S00-S09 Injuries to the head
0.579 0.421 0.000
N80.8 Other endometriosis
0.579 0.421 0.000
N80.6 Endometriosis in cutaneous scar
0.579 0.421 0.000
N80.5 Endometriosis of intestine
0.579 0.421 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.579 0.421 0.000
N80.2 Endometriosis of Fallopian tube
0.579 0.421 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.579 0.421 0.000
M48.9 Spondylopathy, unspecified
0.578 0.422 0.000
M48.8 Other specified spondylopathies
0.578 0.422 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.578 0.422 0.000
M48.4 Fatigue fracture of vertebra
0.578 0.422 0.000
M48.3 Traumatic spondylopathy
0.578 0.422 0.000
M48.2 Kissing spine
0.578 0.422 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.578 0.422 0.000
O32.1 Maternal care for breech presentation
0.578 0.422 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.577 0.423 0.000
M46.8 Other specified inflammatory spondylopathies
0.576 0.424 0.000
M46.5 Other infective spondylopathies
0.576 0.424 0.000
M46.4 Discitis, unspecified
0.576 0.424 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.576 0.424 0.000
M46.2 Osteomyelitis of vertebra
0.576 0.424 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.576 0.424 0.000
M46.0 Spinal enthesopathy
0.576 0.424 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.576 0.424 0.000
N90.6 Hypertrophy of vulva
0.576 0.424 0.000
N90.4 Leukoplakia of vulva
0.576 0.424 0.000
N90.3 Dysplasia of vulva, unspecified
0.576 0.424 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.576 0.424 0.000
N90.1 Moderate vulvar dysplasia
0.576 0.424 0.000
N90.0 Mild vulvar dysplasia
0.576 0.424 0.000
Y84.9 Medical procedure, unspecified
0.575 0.425 0.000
Y84.7 Blood-sampling
0.575 0.425 0.000
Y84.5 Insertion of gastric or duodenal sound
0.575 0.425 0.000
Y84.4 Aspiration of fluid
0.575 0.425 0.000
Y84.3 Shock therapy
0.575 0.425 0.000
Y84.1 Kidney dialysis
0.575 0.425 0.000
H80-H83 Diseases of inner ear
0.574 0.425 0.000
M23 Internal derangement of knee
0.573 0.427 0.000
R07.2 Precordial pain
0.573 0.427 0.000
G43 Migraine
0.572 0.428 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.572 0.428 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.571 0.429 0.000
G96 Other disorders of central nervous system
0.571 0.429 0.000
G95 Other diseases of spinal cord
0.571 0.429 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.571 0.429 0.000
G90 Disorders of autonomic nervous system
0.571 0.429 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.571 0.429 0.000
G92 Toxic encephalopathy
0.571 0.429 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.569 0.430 0.000
N13.8 Other obstructive and reflux uropathy
0.569 0.430 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.569 0.430 0.000
N13.6 Pyonephrosis
0.569 0.430 0.000
N13.4 Hydroureter
0.569 0.430 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.569 0.430 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.569 0.431 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.567 0.433 0.000
G44 Other headache syndromes
0.567 0.433 0.000
G41 Status epilepticus
0.567 0.433 0.000
R12 Heartburn
0.567 0.433 0.000
H34 Retinal vascular occlusions
0.565 0.435 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.565 0.435 0.000
H31 Other disorders of choroid
0.565 0.435 0.000
H30 Chorioretinal inflammation
0.565 0.435 0.000
M25.7 Osteophyte
0.565 0.435 0.000
M48.09 Spinal stenosis (Site unspecified)
0.564 0.436 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.564 0.436 0.000
G36 Other acute disseminated demyelination
0.563 0.437 0.000
N17.8 Other acute renal failure
0.561 0.439 0.000
N17.2 Acute renal failure with medullary necrosis
0.561 0.439 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.561 0.439 0.000
N17.0 Acute renal failure with tubular necrosis
0.561 0.439 0.000
L40.5 Arthropathic psoriasis
0.559 0.441 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.558 0.441 0.000
Q80-Q89 Other congenital malformations
0.558 0.441 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.558 0.441 0.000
Q60-Q64 Congenital malformations of the urinary system
0.558 0.441 0.000
Q50-Q56 Congenital malformations of genital organs
0.558 0.441 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.558 0.441 0.000
Q35-Q37 Cleft lip and cleft palate
0.558 0.441 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.558 0.441 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.558 0.441 0.000
Q00-Q07 Congenital malformations of the nervous system
0.558 0.441 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.558 0.442 0.000
N21.8 Other lower urinary tract calculus
0.558 0.442 0.000
N21.1 Calculus in urethra
0.558 0.442 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.558 0.442 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.558 0.442 0.000
M20.5 Other deformities of toe(s) (acquired)
0.558 0.442 0.000
H53 Visual disturbances
0.555 0.445 0.000
H42 Glaucoma in diseases classified elsewhere
0.554 0.445 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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