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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs183464
log Bayes Factor = 15.6759
Chromosome 6   position 39,073,052  (GRCh37) Explore rs183464 on Ensembl!
Variant rs183464 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
I20 Angina pectoris
0.998 0.002 0.000
E78.0 Pure hypercholesterolaemia
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
I20.0 Unstable angina
0.981 0.019 0.000
I25.2 Old myocardial infarction
0.980 0.020 0.000
E10-E14 Diabetes mellitus
0.980 0.020 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.980 0.020 0.000
I20.9 Angina pectoris, unspecified
0.979 0.021 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
H90-H95 Other disorders of ear
0.974 0.026 0.000
Chapter VI Diseases of the nervous system
0.973 0.027 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.972 0.028 0.000
Chapter I Certain infectious and parasitic diseases
0.970 0.030 0.000
Chapter XI Diseases of the digestive system
0.967 0.033 0.000
R79 Other abnormal findings of blood chemistry
0.966 0.034 0.000
B95-B98 Bacterial, viral and other infectious agents
0.959 0.041 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.956 0.044 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.955 0.045 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.954 0.046 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.952 0.048 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.952 0.048 0.000
E87.5 Hyperkalaemia
0.944 0.056 0.000
I21 Acute myocardial infarction
0.937 0.063 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.929 0.071 0.000
M45-M49 Spondylopathies
0.923 0.077 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.922 0.078 0.000
H91 Other hearing loss
0.918 0.082 0.000
E11 Non-insulin-dependent diabetes mellitus
0.915 0.085 0.000
I30-I52 Other forms of heart disease
0.911 0.089 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.899 0.101 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.898 0.102 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.897 0.103 0.000
I22 Subsequent myocardial infarction
0.893 0.107 0.000
E78.5 Hyperlipidaemia, unspecified
0.891 0.109 0.000
H93 Other disorders of ear, not elsewhere classified
0.886 0.114 0.000
K65-K67 Diseases of peritoneum
0.884 0.116 0.000
E11.9 Without complications
0.879 0.121 0.000
E10 Insulin-dependent diabetes mellitus
0.878 0.121 0.000
H65-H75 Diseases of middle ear and mastoid
0.874 0.126 0.000
G40-G47 Episodic and paroxysmal disorders
0.870 0.130 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.867 0.133 0.000
R42 Dizziness and giddiness
0.865 0.135 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
H91.9 Hearing loss, unspecified
0.853 0.147 0.000
K50-K52 Noninfective enteritis and colitis
0.852 0.148 0.000
M48 Other spondylopathies
0.850 0.150 0.000
I05-I09 Chronic rheumatic heart diseases
0.848 0.151 0.000
I21.9 Acute myocardial infarction, unspecified
0.844 0.156 0.000
E87.7 Fluid overload
0.843 0.157 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.837 0.163 0.000
M80-M85 Disorders of bone density and structure
0.835 0.165 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.835 0.165 0.000
G35 Multiple sclerosis
0.827 0.173 0.000
H93.1 Tinnitus
0.823 0.177 0.000
K08 Other disorders of teeth and supporting structures
0.821 0.179 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.817 0.183 0.000
I24 Other acute ischaemic heart diseases
0.817 0.183 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.816 0.184 0.000
I31 Other diseases of pericardium
0.816 0.184 0.000
K04 Diseases of pulp and periapical tissues
0.807 0.193 0.000
E87.0 Hyperosmolality and hypernatraemia
0.805 0.195 0.000
K51 Ulcerative colitis
0.802 0.198 0.000
M48.0 Spinal stenosis
0.797 0.203 0.000
O80-O84 Delivery
0.792 0.208 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.791 0.209 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.791 0.209 0.000
E20-E35 Disorders of other endocrine glands
0.789 0.211 0.000
Chapter V Mental and behavioural disorders
0.788 0.212 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.787 0.213 0.000
K05 Gingivitis and periodontal diseases
0.787 0.213 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.786 0.214 0.000
Chapter XX External causes of morbidity and mortality
0.785 0.215 0.000
S50-S59 Injuries to the elbow and forearm
0.782 0.218 0.000
K35-K38 Diseases of appendix
0.779 0.221 0.000
M40-M43 Deforming dorsopathies
0.778 0.221 0.000
E13 Other specified diabetes mellitus
0.777 0.222 0.000
K10 Other diseases of jaws
0.777 0.223 0.000
E87.3 Alkalosis
0.774 0.226 0.000
I45 Other conduction disorders
0.772 0.228 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.772 0.228 0.000
I95 Hypotension
0.772 0.228 0.000
M50-M54 Other dorsopathies
0.772 0.228 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.770 0.230 0.000
K14 Diseases of tongue
0.770 0.230 0.000
K65 Peritonitis
0.769 0.231 0.000
M05-M14 Inflammatory polyarthropathies
0.769 0.231 0.000
M65-M68 Disorders of synovium and tendon
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.768 0.232 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.768 0.232 0.000
K07 Dentofacial anomalies [including malocclusion]
0.765 0.235 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.762 0.238 0.000
E50-E64 Other nutritional deficiencies
0.761 0.239 0.000
E10.1 With ketoacidosis
0.760 0.240 0.000
E78.2 Mixed hyperlipidaemia
0.759 0.241 0.000
H60-H62 Diseases of external ear
0.759 0.241 0.000
H91.8 Other specified hearing loss
0.759 0.241 0.000
K00 Disorders of tooth development and eruption
0.758 0.242 0.000
R73 Elevated blood glucose level
0.758 0.242 0.000
R94 Abnormal results of function studies
0.756 0.244 0.000
K66 Other disorders of peritoneum
0.754 0.246 0.000
K12 Stomatitis and related lesions
0.753 0.247 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.753 0.247 0.000
M47 Spondylosis
0.751 0.249 0.000
H90 Conductive and sensorineural hearing loss
0.750 0.250 0.000
E14 Unspecified diabetes mellitus
0.749 0.251 0.000
I08 Multiple valve diseases
0.748 0.251 0.000
H92 Otalgia and effusion of ear
0.748 0.252 0.000
H74 Other disorders of middle ear and mastoid
0.746 0.254 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.745 0.255 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.743 0.257 0.000
M91-M94 Chondropathies
0.743 0.257 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.743 0.257 0.000
G44 Other headache syndromes
0.742 0.258 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.742 0.258 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.740 0.260 0.000
A30-A49 Other bacterial diseases
0.739 0.261 0.000
S60-S69 Injuries to the wrist and hand
0.737 0.263 0.000
E10.9 Without complications
0.737 0.263 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.736 0.264 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.733 0.267 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.731 0.268 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.730 0.270 0.000
G47 Sleep disorders
0.730 0.270 0.000
G57 Mononeuropathies of lower limb
0.730 0.270 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
S20-S29 Injuries to the thorax
0.727 0.273 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.725 0.275 0.000
M48.06 Spinal stenosis (Lumbar region)
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
I50 Heart failure
0.720 0.280 0.000
O14.9 Preeclampsia, unspecified
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E88 Other metabolic disorders
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
M45 Ankylosing spondylitis
0.717 0.283 0.000
E78.8 Other disorders of lipoprotein metabolism
0.716 0.284 0.000
E78.6 Lipoprotein deficiency
0.716 0.284 0.000
E78.4 Other hyperlipidaemia
0.716 0.284 0.000
E78.3 Hyperchylomicronaemia
0.716 0.284 0.000
E78.1 Pure hyperglyceridaemia
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.715 0.285 0.000
I25.5 Ischaemic cardiomyopathy
0.714 0.286 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.714 0.286 0.000
I20.1 Angina pectoris with documented spasm
0.713 0.287 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.289 0.000
G37 Other demyelinating diseases of central nervous system
0.710 0.290 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.710 0.290 0.000
M79.8 Other specified soft tissue disorders
0.708 0.292 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.707 0.292 0.000
R47-R49 Symptoms and signs involving speech and voice
0.707 0.293 0.000
I31.9 Disease of pericardium, unspecified
0.704 0.296 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.703 0.297 0.000
E12 Malnutrition-related diabetes mellitus
0.703 0.297 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.702 0.297 0.000
R77 Other abnormalities of plasma proteins
0.702 0.297 0.000
R76 Other abnormal immunological findings in serum
0.702 0.297 0.000
R74 Abnormal serum enzyme levels
0.702 0.297 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.702 0.297 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.702 0.297 0.000
R71 Abnormality of red blood cells
0.702 0.297 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.702 0.298 0.000
E87.4 Mixed disorder of acid-base balance
0.702 0.298 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.700 0.300 0.000
M60-M63 Disorders of muscles
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
S52 Fracture of forearm
0.699 0.300 0.000
I24.8 Other forms of acute ischaemic heart disease
0.699 0.301 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.698 0.302 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.698 0.302 0.000
I95.1 Orthostatic hypotension
0.698 0.302 0.000
B99-B99 Other infectious diseases
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.695 0.305 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
B50-B64 Protozoal diseases
0.695 0.305 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.695 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.695 0.305 0.000
A80-A89 Viral infections of the central nervous system
0.695 0.305 0.000
A75-A79 Rickettsioses
0.695 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.695 0.305 0.000
A65-A69 Other spirochaetal diseases
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.695 0.305 0.000
A15-A19 Tuberculosis
0.695 0.305 0.000
H71 Cholesteatoma of middle ear
0.695 0.305 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.693 0.307 0.000
I34 Nonrheumatic mitral valve disorders
0.693 0.307 0.000
E11.4 With neurological complications
0.693 0.307 0.000
O80 Single spontaneous delivery
0.693 0.307 0.000
R79.0 Abnormal level of blood mineral
0.692 0.308 0.000
K11 Diseases of salivary glands
0.692 0.308 0.000
Chapter X Diseases of the respiratory system
0.691 0.309 0.000
G40 Epilepsy
0.691 0.309 0.000
K70-K77 Diseases of liver
0.691 0.309 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.691 0.309 0.000
E65-E68 Obesity and other hyperalimentation
0.691 0.309 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.689 0.311 0.000
I33 Acute and subacute endocarditis
0.689 0.311 0.000
I49 Other cardiac arrhythmias
0.688 0.312 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.686 0.314 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.684 0.316 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.684 0.316 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.684 0.316 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.683 0.317 0.000
K09 Cysts of oral region, not elsewhere classified
0.682 0.317 0.000
K03 Other diseases of hard tissues of teeth
0.682 0.317 0.000
M80 Osteoporosis with pathological fracture
0.682 0.318 0.000
T66-T78 Other and unspecified effects of external causes
0.680 0.320 0.000
B25-B34 Other viral diseases
0.680 0.320 0.000
K51.8 Other ulcerative colitis
0.679 0.321 0.000
I21.4 Acute subendocardial myocardial infarction
0.678 0.322 0.000
I46 Cardiac arrest
0.677 0.323 0.000
H72 Perforation of tympanic membrane
0.677 0.323 0.000
I31.3 Pericardial effusion (noninflammatory)
0.676 0.324 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.676 0.324 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
M86-M90 Other osteopathies
0.674 0.325 0.000
G30-G32 Other degenerative diseases of the nervous system
0.674 0.325 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.674 0.326 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.674 0.326 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.674 0.326 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.674 0.326 0.000
O16 Unspecified maternal hypertension
0.673 0.326 0.000
K04.8 Radicular cyst
0.673 0.326 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.673 0.327 0.000
O60-O75 Complications of labour and delivery
0.672 0.328 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.672 0.328 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.672 0.328 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.672 0.328 0.000
I45.1 Other and unspecified right bundle-branch block
0.671 0.329 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.670 0.330 0.000
I95.2 Hypotension due to drugs
0.669 0.331 0.000
G57.6 Lesion of plantar nerve
0.667 0.333 0.000
O85-O92 Complications predominantly related to the puerperium
0.666 0.334 0.000
K35 Acute appendicitis
0.665 0.335 0.000
H80-H83 Diseases of inner ear
0.664 0.336 0.000
K51.9 Ulcerative colitis, unspecified
0.663 0.337 0.000
H66 Suppurative and unspecified otitis media
0.663 0.337 0.000
M48.09 Spinal stenosis (Site unspecified)
0.662 0.338 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.338 0.000
M46 Other inflammatory spondylopathies
0.661 0.339 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.661 0.339 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.660 0.340 0.000
M72 Fibroblastic disorders
0.659 0.341 0.000
H91.3 Deaf mutism, not elsewhere classified
0.658 0.342 0.000
H91.2 Sudden idiopathic hearing loss
0.658 0.342 0.000
H91.1 Presbycusis
0.658 0.342 0.000
H91.0 Ototoxic hearing loss
0.658 0.342 0.000
E11.8 With unspecified complications
0.656 0.344 0.000
E11.7 With multiple complications
0.656 0.344 0.000
E11.6 With other specified complications
0.656 0.344 0.000
E11.5 With peripheral circulatory complications
0.656 0.344 0.000
E11.2 With renal complications
0.656 0.344 0.000
E11.1 With ketoacidosis
0.656 0.344 0.000
E11.0 With coma
0.656 0.344 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.655 0.345 0.000
K05.1 Chronic gingivitis
0.655 0.345 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.655 0.345 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.654 0.346 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.653 0.347 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.653 0.347 0.000
I52 Other heart disorders in diseases classified elsewhere
0.653 0.347 0.000
I48 Atrial fibrillation and flutter
0.653 0.347 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.653 0.347 0.000
I41 Myocarditis in diseases classified elsewhere
0.653 0.347 0.000
I40 Acute myocarditis
0.653 0.347 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.653 0.347 0.000
I37 Pulmonary valve disorders
0.653 0.347 0.000
I36 Nonrheumatic tricuspid valve disorders
0.653 0.347 0.000
I32 Pericarditis in diseases classified elsewhere
0.653 0.347 0.000
I30 Acute pericarditis
0.653 0.347 0.000
I42 Cardiomyopathy
0.652 0.347 0.000
K65.9 Peritonitis, unspecified
0.652 0.348 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.652 0.348 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.651 0.349 0.000
K10.8 Other specified diseases of jaws
0.651 0.349 0.000
K01 Embedded and impacted teeth
0.650 0.350 0.000
K51.2 Ulcerative (chronic) proctitis
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.649 0.351 0.000
R82 Other abnormal findings in urine
0.647 0.352 0.000
R94.3 Abnormal results of cardiovascular function studies
0.647 0.352 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.647 0.353 0.000
G36 Other acute disseminated demyelination
0.645 0.355 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.644 0.356 0.000
R46 Symptoms and signs involving appearance and behaviour
0.644 0.356 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.644 0.356 0.000
R43 Disturbances of smell and taste
0.644 0.356 0.000
K04.5 Chronic apical periodontitis
0.644 0.356 0.000
M79.6 Pain in limb
0.644 0.356 0.000
T79-T79 Certain early complications of trauma
0.643 0.357 0.000
T33-T35 Frostbite
0.643 0.357 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.643 0.357 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.643 0.357 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.643 0.357 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.643 0.357 0.000
T00-T07 Injuries involving multiple body regions
0.643 0.357 0.000
S10-S19 Injuries to the neck
0.643 0.357 0.000
G54 Nerve root and plexus disorders
0.643 0.357 0.000
R30-R39 Symptoms and signs involving the urinary system
0.642 0.358 0.000
I22.8 Subsequent myocardial infarction of other sites
0.640 0.359 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.639 0.361 0.000
M06 Other rheumatoid arthritis
0.637 0.363 0.000
M50 Cervical disk disorders
0.637 0.363 0.000
E87.6 Hypokalaemia
0.635 0.365 0.000
H93.9 Disorder of ear, unspecified
0.635 0.365 0.000
H93.8 Other specified disorders of ear
0.635 0.365 0.000
H93.3 Disorders of acoustic nerve
0.635 0.365 0.000
H93.2 Other abnormal auditory perceptions
0.635 0.365 0.000
H93.0 Degenerative and vascular disorders of ear
0.635 0.365 0.000
M47.9 Spondylosis, unspecified
0.635 0.365 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.635 0.365 0.000
S52.5 Fracture of lower end of radius
0.635 0.365 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.634 0.366 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.634 0.366 0.000
E13.9 Without complications
0.632 0.368 0.000
K66.0 Peritoneal adhesions
0.632 0.368 0.000
M71 Other bursopathies
0.631 0.369 0.000
K07.6 Temporomandibular joint disorders
0.631 0.369 0.000
E10.8 With unspecified complications
0.630 0.370 0.000
E10.7 With multiple complications
0.630 0.370 0.000
E10.6 With other specified complications
0.630 0.370 0.000
E10.5 With peripheral circulatory complications
0.630 0.370 0.000
E10.4 With neurological complications
0.630 0.370 0.000
E10.2 With renal complications
0.630 0.370 0.000
E10.0 With coma
0.630 0.370 0.000
R45 Symptoms and signs involving emotional state
0.629 0.371 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.629 0.371 0.000
M65 Synovitis and tenosynovitis
0.629 0.371 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.627 0.373 0.000
H70 Mastoiditis and related conditions
0.627 0.373 0.000
H69 Other disorders of Eustachian tube
0.627 0.373 0.000
H68 Eustachian salpingitis and obstruction
0.627 0.373 0.000
H67 Otitis media in diseases classified elsewhere
0.627 0.373 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.626 0.374 0.000
I51 Complications and ill-defined descriptions of heart disease
0.625 0.375 0.000
S64 Injury of nerves at wrist and hand level
0.624 0.375 0.000
K08.3 Retained dental root
0.624 0.375 0.000
K29 Gastritis and duodenitis
0.625 0.375 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.624 0.376 0.000
G41 Status epilepticus
0.624 0.376 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.623 0.377 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.622 0.378 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.622 0.378 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.622 0.378 0.000
I99 Other and unspecified disorders of circulatory system
0.622 0.378 0.000
S70-S79 Injuries to the hip and thigh
0.620 0.380 0.000
M76 Enthesopathies of lower limb, excluding foot
0.620 0.380 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.620 0.380 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.620 0.380 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.619 0.380 0.000
K00.6 Disturbances in tooth eruption
0.619 0.381 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.618 0.382 0.000
I50.0 Congestive heart failure
0.618 0.382 0.000
G44.0 Cluster headache syndrome
0.618 0.382 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.617 0.383 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.617 0.383 0.000
K13 Other diseases of lip and oral mucosa
0.616 0.384 0.000
K29.6 Other gastritis
0.616 0.384 0.000
K50 Crohn's disease [regional enteritis]
0.616 0.384 0.000
M77 Other enthesopathies
0.614 0.386 0.000
M10 Gout
0.614 0.386 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.613 0.387 0.000
R30 Pain associated with micturition
0.612 0.388 0.000
K14.0 Glossitis
0.611 0.389 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.610 0.390 0.000
E10.3 With ophthalmic complications
0.610 0.390 0.000
K12.1 Other forms of stomatitis
0.610 0.390 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.610 0.390 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.609 0.390 0.000
M48.9 Spondylopathy, unspecified
0.609 0.391 0.000
M48.8 Other specified spondylopathies
0.609 0.391 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.609 0.391 0.000
M48.4 Fatigue fracture of vertebra
0.609 0.391 0.000
M48.3 Traumatic spondylopathy
0.609 0.391 0.000
M48.2 Kissing spine
0.609 0.391 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.609 0.391 0.000
V20-V29 Motorcycle rider injured in transport accident
0.609 0.391 0.000
I09 Other rheumatic heart diseases
0.608 0.392 0.000
I06 Rheumatic aortic valve diseases
0.608 0.392 0.000
I05 Rheumatic mitral valve diseases
0.608 0.392 0.000
I47 Paroxysmal tachycardia
0.608 0.392 0.000
W00-W19 Falls
0.606 0.394 0.000
I44 Atrioventricular and left bundle-branch block
0.606 0.394 0.000
R06 Abnormalities of breathing
0.605 0.395 0.000
G72 Other myopathies
0.604 0.396 0.000
M43 Other deforming dorsopathies
0.603 0.397 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.602 0.398 0.000
K65.8 Other peritonitis
0.602 0.398 0.000
W20-W49 Exposure to inanimate mechanical forces
0.602 0.398 0.000
G62 Other polyneuropathies
0.601 0.398 0.000
M41 Scoliosis
0.600 0.400 0.000
O15 Eclampsia
0.600 0.400 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.600 0.400 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.600 0.400 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.600 0.400 0.000
O80.0 Spontaneous vertex delivery
0.600 0.400 0.000
H73 Other disorders of tympanic membrane
0.600 0.400 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.599 0.401 0.000
M83 Adult osteomalacia
0.599 0.401 0.000
M82 Osteoporosis in diseases classified elsewhere
0.599 0.401 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.599 0.401 0.000
G20-G26 Extrapyramidal and movement disorders
0.599 0.401 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.598 0.401 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.598 0.401 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.598 0.401 0.000
K55-K64 Other diseases of intestines
0.598 0.402 0.000
T86 Failure and rejection of transplanted organs and tissues
0.596 0.403 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.596 0.404 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.594 0.406 0.000
E80.4 Gilbert's syndrome
0.592 0.408 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.591 0.409 0.000
K66.8 Other specified disorders of peritoneum
0.590 0.410 0.000
K38 Other diseases of appendix
0.590 0.410 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.589 0.411 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.589 0.411 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.589 0.411 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.589 0.411 0.000
R73.0 Abnormal glucose tolerance test
0.589 0.411 0.000
I07 Rheumatic tricuspid valve diseases
0.588 0.412 0.000
S52.50 Fracture of lower end of radius (closed)
0.588 0.412 0.000
G44.2 Tension-type headache
0.587 0.413 0.000
R25 Abnormal involuntary movements
0.587 0.413 0.000
K05.3 Chronic periodontitis
0.587 0.413 0.000
H92.0 Otalgia
0.587 0.413 0.000
M48.02 Spinal stenosis (Cervical region)
0.586 0.414 0.000
G58 Other mononeuropathies
0.586 0.414 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.586 0.414 0.000
G52 Disorders of other cranial nerves
0.586 0.414 0.000
O42 Premature rupture of membranes
0.586 0.414 0.000
I24.1 Dressler's syndrome
0.586 0.414 0.000
E29 Testicular dysfunction
0.586 0.414 0.000
E86 Volume depletion
0.586 0.414 0.000
M79.66 Pain in limb (Lower leg)
0.586 0.414 0.000
I31.8 Other specified diseases of pericardium
0.585 0.415 0.000
I31.2 Haemopericardium, not elsewhere classified
0.585 0.415 0.000
I31.1 Chronic constrictive pericarditis
0.585 0.415 0.000
I31.0 Chronic adhesive pericarditis
0.585 0.415 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.584 0.416 0.000
E14.9 Without complications
0.584 0.416 0.000
M51 Other intervertebral disk disorders
0.583 0.417 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.582 0.418 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.581 0.418 0.000
S40-S49 Injuries to the shoulder and upper arm
0.581 0.419 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.581 0.419 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.581 0.419 0.000
B35-B49 Mycoses
0.581 0.419 0.000
R30.0 Dysuria
0.580 0.420 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.580 0.420 0.000
H65 Nonsuppurative otitis media
0.579 0.421 0.000
I20.8 Other forms of angina pectoris
0.578 0.421 0.000
E61 Deficiency of other nutrient elements
0.578 0.422 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.578 0.422 0.000
K04.6 Periapical abscess with sinus
0.578 0.422 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.578 0.422 0.000
K04.3 Abnormal hard tissue formation in pulp
0.578 0.422 0.000
K04.2 Pulp degeneration
0.578 0.422 0.000
K04.1 Necrosis of pulp
0.578 0.422 0.000
K04.0 Pulpitis
0.578 0.422 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.577 0.423 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.577 0.423 0.000
R40 Somnolence, stupor and coma
0.576 0.424 0.000
E89.0 Postprocedural hypothyroidism
0.575 0.425 0.000
M93 Other osteochondropathies
0.575 0.425 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.575 0.425 0.000
K51.5 Mucosal proctocolitis
0.575 0.425 0.000
K51.4 Pseudopolyposis of colon
0.575 0.425 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.575 0.425 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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