TreeWAS – Variant ID: rs184074

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I08.1 Disorders of both mitral and tricuspid valves	0.285	0.715	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.281	0.719	0.000
I08 Multiple valve diseases	0.272	0.728	0.000
I08.8 Other multiple valve diseases	0.198	0.802	0.000
I08.9 Multiple valve disease, unspecified	0.161	0.839	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.157	0.843	0.000
I08.0 Disorders of both mitral and aortic valves	0.119	0.881	0.000
I05-I09 Chronic rheumatic heart diseases	0.091	0.909	0.000
I06 Rheumatic aortic valve diseases	0.070	0.930	0.000
I09 Other rheumatic heart diseases	0.061	0.938	0.000
I05 Rheumatic mitral valve diseases	0.061	0.939	0.000
I07 Rheumatic tricuspid valve diseases	0.060	0.940	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.054	0.946	0.000
I06.1 Rheumatic aortic insufficiency	0.052	0.948	0.000
N13.3 Other and unspecified hydronephrosis	0.051	0.949	0.000
I06.8 Other rheumatic aortic valve diseases	0.050	0.950	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.050	0.950	0.000
I05.2 Mitral stenosis with insufficiency	0.050	0.950	0.000
I06.0 Rheumatic aortic stenosis	0.049	0.950	0.000
I05.8 Other mitral valve diseases	0.048	0.952	0.000
N13 Obstructive and reflux uropathy	0.045	0.955	0.000
I09.8 Other specified rheumatic heart diseases	0.044	0.956	0.000
I09.2 Chronic rheumatic pericarditis	0.044	0.956	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.044	0.956	0.000
I09.0 Rheumatic myocarditis	0.044	0.956	0.000
I07.9 Tricuspid valve disease, unspecified	0.043	0.957	0.000
I07.8 Other tricuspid valve diseases	0.043	0.957	0.000
I07.2 Tricuspid stenosis with insufficiency	0.043	0.957	0.000
I07.0 Tricuspid stenosis	0.043	0.957	0.000
I05.1 Rheumatic mitral insufficiency	0.043	0.957	0.000
N13.4 Hydroureter	0.042	0.958	0.000
I05.0 Mitral stenosis	0.042	0.958	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.040	0.960	0.000
I09.9 Rheumatic heart disease, unspecified	0.040	0.960	0.000
N13.8 Other obstructive and reflux uropathy	0.038	0.962	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.038	0.962	0.000
I07.1 Tricuspid insufficiency	0.038	0.962	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.037	0.963	0.000
K60.2 Anal fissure, unspecified	0.000	0.971	0.029
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.029	0.971	0.000
N13.6 Pyonephrosis	0.025	0.975	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.024	0.976	0.000
I05.9 Mitral valve disease, unspecified	0.023	0.977	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.021	0.979	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.979	0.021
M41.9 Scoliosis, unspecified	0.000	0.981	0.019
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.981	0.019
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.982	0.018
H36.0 Diabetic retinopathy	0.018	0.982	0.000
N60.4 Mammary duct ectasia	0.000	0.982	0.018
N60.8 Other benign mammary dysplasias	0.000	0.982	0.018
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.983	0.017
N60 Benign mammary dysplasia	0.000	0.983	0.017
O63.1 Prolonged second stage (of labour)	0.017	0.983	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.985	0.015
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.985	0.014
N60.2 Fibroadenosis of breast	0.000	0.986	0.014
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.986	0.014
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.986	0.013
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.986	0.013
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.988	0.012
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.988	0.012
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.989	0.011
N10-N16 Renal tubulo-interstitial diseases	0.010	0.990	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.990	0.010
M41 Scoliosis	0.000	0.991	0.009
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.991	0.009
E27.4 Other and unspecified adrenocortical insufficiency	0.009	0.991	0.000
N15 Other renal tubulo-interstitial diseases	0.009	0.991	0.000
N11 Chronic tubulo-interstitial nephritis	0.009	0.991	0.000
N60.0 Solitary cyst of breast	0.000	0.991	0.008
N11.1 Chronic obstructive pyelonephritis	0.008	0.992	0.000
H36 Retinal disorders in diseases classified elsewhere	0.008	0.992	0.000
N15.1 Renal and perinephric abscess	0.008	0.992	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.008	0.992	0.000
O20.0 Threatened abortion	0.008	0.992	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.008	0.992	0.000
M41.5 Other secondary scoliosis	0.000	0.993	0.007
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.007	0.993	0.000
M41.8 Other forms of scoliosis	0.000	0.993	0.007
M41.3 Thoracogenic scoliosis	0.000	0.993	0.007
M41.2 Other idiopathic scoliosis	0.000	0.993	0.007
M41.1 Juvenile idiopathic scoliosis	0.000	0.993	0.007
M41.0 Infantile idiopathic scoliosis	0.000	0.993	0.007
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
N15.8 Other specified renal tubulo-interstitial diseases	0.007	0.993	0.000
N15.0 Balkan nephropathy	0.007	0.993	0.000
M41.4 Neuromuscular scoliosis	0.000	0.993	0.006
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.006	0.993	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.006	0.993	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.000	0.994	0.006
J43.9 Emphysema, unspecified	0.006	0.994	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.006	0.994	0.000
R57.0 Cardiogenic shock	0.006	0.994	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.000	0.994	0.006
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.006	0.994	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.000	0.994	0.005
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.000	0.994	0.005
M41.57 Other secondary scoliosis (Lumbosacral region)	0.000	0.994	0.005
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.000	0.994	0.005
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.000	0.994	0.005
M41.52 Other secondary scoliosis (Cervical region)	0.000	0.994	0.005
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.000	0.994	0.005
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.000	0.994	0.005
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.005	0.994	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.005	0.994	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.005	0.994	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.005	0.994	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.005	0.994	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.005	0.994	0.000
M41.89 Other forms of scoliosis (Site unspecified)	0.000	0.994	0.005
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)	0.000	0.994	0.005
M41.87 Other forms of scoliosis (Lumbosacral region)	0.000	0.994	0.005
M41.85 Other forms of scoliosis (Thoracolumbar region)	0.000	0.994	0.005
M41.84 Other forms of scoliosis (Thoracic region)	0.000	0.994	0.005
M41.83 Other forms of scoliosis (Cervicothoracic region)	0.000	0.994	0.005
M41.82 Other forms of scoliosis (Cervical region)	0.000	0.994	0.005
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)	0.000	0.994	0.005
M41.80 Other forms of scoliosis (Multiple sites in spine)	0.000	0.994	0.005
M41.09 Infantile idiopathic scoliosis (Site unspecified)	0.000	0.995	0.005
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)	0.000	0.995	0.005
M41.06 Infantile idiopathic scoliosis (Lumbar region)	0.000	0.995	0.005
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)	0.000	0.995	0.005
M41.04 Infantile idiopathic scoliosis (Thoracic region)	0.000	0.995	0.005
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)	0.000	0.995	0.005
M41.02 Infantile idiopathic scoliosis (Cervical region)	0.000	0.995	0.005
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)	0.000	0.995	0.005
M41.19 Juvenile idiopathic scoliosis (Site unspecified)	0.000	0.995	0.005
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)	0.000	0.995	0.005
M41.16 Juvenile idiopathic scoliosis (Lumbar region)	0.000	0.995	0.005
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)	0.000	0.995	0.005
M41.14 Juvenile idiopathic scoliosis (Thoracic region)	0.000	0.995	0.005
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)	0.000	0.995	0.005
M41.12 Juvenile idiopathic scoliosis (Cervical region)	0.000	0.995	0.005
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)	0.000	0.995	0.005
M41.29 Other idiopathic scoliosis (Site unspecified)	0.000	0.995	0.005
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M41.27 Other idiopathic scoliosis (Lumbosacral region)	0.000	0.995	0.005
M41.26 Other idiopathic scoliosis (Lumbar region)	0.000	0.995	0.005
M41.25 Other idiopathic scoliosis (Thoracolumbar region)	0.000	0.995	0.005
M41.24 Other idiopathic scoliosis (Thoracic region)	0.000	0.995	0.005
M41.23 Other idiopathic scoliosis (Cervicothoracic region)	0.000	0.995	0.005
M41.22 Other idiopathic scoliosis (Cervical region)	0.000	0.995	0.005
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
M41.20 Other idiopathic scoliosis (Multiple sites in spine)	0.000	0.995	0.005
M41.39 Thoracogenic scoliosis-Site unspe	0.000	0.995	0.005
M41.38 Thoracogenic scoliosis-Sacral/sacrococ	0.000	0.995	0.005
M41.37 Thoracogenic scoliosis-Lumbosacral	0.000	0.995	0.005
M41.36 Thoracogenic scoliosis-Lumbar	0.000	0.995	0.005
M41.35 Thoracogenic scoliosis (Thoracolumbar region)	0.000	0.995	0.005
M41.34 Thoracogenic scoliosis (Thoracic region)	0.000	0.995	0.005
M41.33 Thoracogenic scoliosis (Cervicothoracic region)	0.000	0.995	0.005
M41.32 Thoracogenic scoliosis-Cervical	0.000	0.995	0.005
M41.31 Thoracogenic scoliosis-Occipit-atl-axl	0.000	0.995	0.005
M41.30 Thoracogenic scoliosis (Multiple sites in spine)	0.000	0.995	0.005
M41.54 Other secondary scoliosis (Thoracic region)	0.000	0.995	0.005
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.005	0.995	0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M41.47 Neuromuscular scoliosis (Lumbosacral region)	0.000	0.995	0.005
M41.46 Neuromuscular scoliosis (Lumbar region)	0.000	0.995	0.005
M41.45 Neuromuscular scoliosis (Thoracolumbar region)	0.000	0.995	0.005
M41.44 Neuromuscular scoliosis (Thoracic region)	0.000	0.995	0.005
M41.43 Neuromuscular scoliosis (Cervicothoracic region)	0.000	0.995	0.005
M41.42 Neuromuscular scoliosis (Cervical region)	0.000	0.995	0.005
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
M41.40 Neuromuscular scoliosis (Multiple sites in spine)	0.000	0.995	0.005
N14.4 Toxic nephropathy, not elsewhere classified	0.005	0.995	0.000
N14.3 Nephropathy induced by heavy metals	0.005	0.995	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.005	0.995	0.000
N14.0 Analgesic nephropathy	0.005	0.995	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.005	0.995	0.000
C05 Malignant neoplasm of palate	0.005	0.995	0.000
C01 Malignant neoplasm of base of tongue	0.005	0.995	0.000
M41.49 Neuromuscular scoliosis (Site unspecified)	0.000	0.995	0.004
K11.2 Sialoadenitis	0.005	0.995	0.000
C04 Malignant neoplasm of floor of mouth	0.004	0.995	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.004	0.996	0.000
N60.3 Fibrosclerosis of breast	0.000	0.996	0.004
C12 Malignant neoplasm of pyriform sinus	0.004	0.996	0.000
C04.9 Floor of mouth, unspecified	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
C07 Malignant neoplasm of parotid gland	0.004	0.996	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.996	0.004
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.004	0.996	0.000
K86.1 Other chronic pancreatitis	0.004	0.996	0.000
F52.2 Failure of genital response	0.000	0.996	0.004
C05.0 Hard palate	0.004	0.996	0.000
C14.0 Pharynx, unspecified	0.004	0.996	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.004	0.996	0.000
C05.1 Soft palate	0.004	0.996	0.000
E10.3 With ophthalmic complications	0.004	0.996	0.000
O20 Haemorrhage in early pregnancy	0.004	0.996	0.000
C03 Malignant neoplasm of gum	0.004	0.996	0.000
C05.9 Palate, unspecified	0.004	0.996	0.000
K60.0 Acute anal fissure	0.000	0.996	0.004
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.004	0.996	0.000
S19.9 Unspecified injury of neck	0.000	0.996	0.004
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.004	0.996	0.000
C13 Malignant neoplasm of hypopharynx	0.004	0.996	0.000
C04.0 Anterior floor of mouth	0.004	0.996	0.000
O22.4 Haemorrhoids in pregnancy	0.004	0.996	0.000
D23.1 Skin of eyelid, including canthus	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
C05.8 Overlapping lesion of palate	0.003	0.996	0.000
C05.2 Uvula	0.003	0.996	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.004	0.996	0.000
C08.9 Major salivary gland, unspecified	0.003	0.996	0.000
Z36.8 Other antenatal screening	0.004	0.996	0.000
C04.8 Overlapping lesion of floor of mouth	0.003	0.996	0.000
C04.1 Lateral floor of mouth	0.003	0.996	0.000
K04.6 Periapical abscess with sinus	0.004	0.996	0.000
C11 Malignant neoplasm of nasopharynx	0.003	0.997	0.000
C00 Malignant neoplasm of lip	0.003	0.997	0.000
C14.2 Waldeyer's ring	0.003	0.997	0.000
R57 Shock, not elsewhere classified	0.003	0.997	0.000
C03.1 Lower gum	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.003	0.997	0.000
E13.9 Without complications	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.003	0.997	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.003	0.997	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.003	0.997	0.000
K60.5 Anorectal fistula	0.000	0.997	0.003
C13.9 Hypopharynx, unspecified	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
C10 Malignant neoplasm of oropharynx	0.003	0.997	0.000
C08.8 Overlapping lesion of major salivary glands	0.003	0.997	0.000
C08.1 Sublingual gland	0.003	0.997	0.000
C03.9 Gum, unspecified	0.003	0.997	0.000
C03.0 Upper gum	0.003	0.997	0.000
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
K60.4 Rectal fistula	0.000	0.997	0.003
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
R57.2 Septic shock	0.003	0.997	0.000
C08.0 Submandibular gland	0.003	0.997	0.000
R57.1 Hypovolaemic shock	0.003	0.997	0.000
C13.8 Overlapping lesion of hypopharynx	0.003	0.997	0.000
C13.2 Posterior wall of hypopharynx	0.003	0.997	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
K86 Other diseases of pancreas	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.003	0.997	0.000
C00.0 External upper lip	0.003	0.997	0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
K86.2 Cyst of pancreas	0.003	0.997	0.000
L95.9 Vasculitis limited to skin, unspecified	0.000	0.997	0.003
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.003	0.997	0.000
J43 Emphysema	0.003	0.997	0.000
O24 Diabetes mellitus in pregnancy	0.003	0.997	0.000
C13.0 Postcricoid region	0.003	0.997	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
O22.3 Deep phlebothrombosis in pregnancy	0.003	0.997	0.000
C11.8 Overlapping lesion of nasopharynx	0.003	0.997	0.000
C11.3 Anterior wall of nasopharynx	0.003	0.997	0.000
C11.2 Lateral wall of nasopharynx	0.003	0.997	0.000
C11.0 Superior wall of nasopharynx	0.003	0.997	0.000
C00.8 Overlapping lesion of lip	0.003	0.997	0.000
C00.6 Commissure of lip	0.003	0.997	0.000
C00.5 Lip, unspecified, inner aspect	0.003	0.997	0.000
C00.4 Lower lip, inner aspect	0.003	0.997	0.000
C00.3 Upper lip, inner aspect	0.003	0.997	0.000
C00.2 External lip, unspecified	0.003	0.997	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.003	0.997	0.000
R57.8 Other shock	0.003	0.997	0.000
C00.9 Lip, unspecified	0.003	0.997	0.000
C11.9 Nasopharynx, unspecified	0.003	0.997	0.000
K61.3 Ischiorectal abscess	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
O22.9 Venous complication in pregnancy, unspecified	0.003	0.997	0.000
O22.8 Other venous complications in pregnancy	0.003	0.997	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.003	0.997	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.003	0.997	0.000
C06.9 Mouth, unspecified	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
C11.1 Posterior wall of nasopharynx	0.002	0.997	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.997	0.003
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.002	0.997	0.000
C06.1 Vestibule of mouth	0.002	0.997	0.000
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.003	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.002	0.997	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.002	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.997	0.003
C10.8 Overlapping lesion of oropharynx	0.002	0.997	0.000
C10.4 Branchial cleft	0.002	0.997	0.000
C10.3 Posterior wall of oropharynx	0.002	0.997	0.000
C10.2 Lateral wall of oropharynx	0.002	0.997	0.000
C10.1 Anterior surface of epiglottis	0.002	0.997	0.000
C10.0 Vallecula	0.002	0.997	0.000
O22.1 Genital varices in pregnancy	0.002	0.997	0.000
R57.9 Shock, unspecified	0.002	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.997	0.000
O25 Malnutrition in pregnancy	0.002	0.997	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
J43.8 Other emphysema	0.002	0.998	0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
K61.1 Rectal abscess	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.998	0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.002	0.998	0.000
C06.0 Cheek mucosa	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
C00.1 External lower lip	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
C06.2 Retromolar area	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.001
O28.8 Other abnormal findings on antenatal screening of mother	0.002	0.998	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.002	0.998	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.002	0.998	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
J43.1 Panlobular emphysema	0.002	0.998	0.000
J43.0 MacLeod's syndrome	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.002	0.998	0.000
C02.0 Dorsal surface of tongue	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.002	0.998	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
C02.2 Ventral surface of tongue	0.002	0.998	0.000
O26.5 Maternal hypotension syndrome	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
F52.0 Lack or loss of sexual desire	0.000	0.998	0.002
J43.2 Centrilobular emphysema	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.002	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.002	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.002	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.002	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.002	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
E29 Testicular dysfunction	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
O26.4 Herpes gestationis	0.002	0.998	0.000
O26.1 Low weight gain in pregnancy	0.002	0.998	0.000
O26.0 Excessive weight gain in pregnancy	0.002	0.998	0.000
C02.4 Lingual tonsil	0.002	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O63 Long labour	0.002	0.998	0.000
M40-M43 Deforming dorsopathies	0.000	0.998	0.002
C09.8 Overlapping lesion of tonsil	0.002	0.998	0.000
T87.4 Infection of amputation stump	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F52.7 Excessive sexual drive	0.000	0.998	0.002
F52.6 Nonorganic dyspareunia	0.000	0.998	0.002
F52.5 Nonorganic vaginismus	0.000	0.998	0.002
F52.4 Premature ejaculation	0.000	0.998	0.002
F52.3 Orgasmic dysfunction	0.000	0.998	0.002
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.002	0.998	0.000
C09.0 Tonsillar fossa	0.002	0.998	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
H02.0 Entropion and trichiasis of eyelid	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.000	0.998	0.002
Z40.9 Prophylactic surgery, unspecified	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.002	0.998	0.000
K11 Diseases of salivary glands	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
K26.0 Acute with haemorrhage	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
K11.9 Disease of salivary gland, unspecified	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.001	0.998	0.000
S01.0 Open wound of scalp	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
Z40 Prophylactic surgery	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
M42 Spinal osteochondrosis	0.000	0.998	0.002
S52.61 Fracture of lower end of both ulna and radius (open)	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
N84.2 Polyp of vagina	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
K11.3 Abscess of salivary gland	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.000	0.998	0.001
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
K11.4 Fistula of salivary gland	0.002	0.998	0.000
K11.0 Atrophy of salivary gland	0.002	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
Z74.8 Other problems related to care-provider dependency	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.001	0.998	0.000
K11.1 Hypertrophy of salivary gland	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.000	0.998	0.002
S19.8 Other specified injuries of neck	0.000	0.998	0.001
K04 Diseases of pulp and periapical tissues	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.998	0.000
E24.1 Nelson's syndrome	0.001	0.998	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
K61 Abscess of anal and rectal regions	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations