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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1842399
log Bayes Factor = 45.8697
Chromosome 6   position 32,753,313  (GRCh37) Explore rs1842399 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
C44.6 Skin of upper limb, including shoulder
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.006 0.994
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.006 0.994
E20-E35 Disorders of other endocrine glands
0.000 0.006 0.994
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.007 0.993
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
L40-L45 Papulosquamous disorders
0.000 0.009 0.991
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
E10.9 Without complications
0.000 0.012 0.988
E10.3 With ophthalmic complications
0.000 0.012 0.988
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.014 0.986
E23 Hypofunction and other disorders of pituitary gland
0.000 0.016 0.984
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.016 0.984
G35-G37 Demyelinating diseases of the central nervous system
0.984 0.016 0.000
Chapter II Neoplasms
0.000 0.016 0.984
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.017 0.983
D00-D09 In situ neoplasms
0.000 0.017 0.983
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.019 0.981
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.022 0.978
G37 Other demyelinating diseases of central nervous system
0.978 0.022 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.023 0.977
D04 Carcinoma in situ of skin
0.000 0.025 0.975
C44.2 Skin of ear and external auricular canal
0.000 0.029 0.971
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.029 0.971
G37.9 Demyelinating disease of central nervous system, unspecified
0.968 0.032 0.000
D06 Carcinoma in situ of cervix uteri
0.000 0.035 0.965
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.038 0.962
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.041 0.959
D06.9 Cervix, unspecified
0.000 0.047 0.953
C83.3 Large cell (diffuse)
0.000 0.053 0.947
D04.3 Skin of other and unspecified parts of face
0.000 0.080 0.920
E23.7 Disorder of pituitary gland, unspecified
0.000 0.080 0.920
E83.1 Disorders of iron metabolism
0.917 0.083 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.087 0.913
L43 Lichen planus
0.000 0.087 0.913
C85.1 B-cell lymphoma, unspecified
0.000 0.088 0.912
E23.6 Other disorders of pituitary gland
0.000 0.093 0.907
E70-E90 Metabolic disorders
0.000 0.094 0.906
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.097 0.903
E27 Other disorders of adrenal gland
0.000 0.101 0.899
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.101 0.899
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.105 0.895
E06 Thyroiditis
0.000 0.106 0.894
C43 Malignant melanoma of skin
0.000 0.109 0.891
E78.0 Pure hypercholesterolaemia
0.000 0.115 0.885
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.116 0.884
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.120 0.880
D04.5 Skin of trunk
0.000 0.125 0.875
G37.8 Other specified demyelinating diseases of central nervous system
0.874 0.126 0.000
E10.1 With ketoacidosis
0.000 0.130 0.870
E10.5 With peripheral circulatory complications
0.000 0.135 0.865
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.139 0.861
E11.3 With ophthalmic complications
0.000 0.147 0.853
C44.4 Skin of scalp and neck
0.000 0.147 0.853
E06.3 Autoimmune thyroiditis
0.000 0.148 0.852
E23.2 Diabetes insipidus
0.000 0.149 0.851
L40.0 Psoriasis vulgaris
0.000 0.157 0.843
M06.0 Seronegative rheumatoid arthritis
0.000 0.159 0.841
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.160 0.840
E27.1 Primary adrenocortical insufficiency
0.000 0.162 0.838
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.163 0.837
E10.0 With coma
0.000 0.164 0.836
L82 Seborrhoeic keratosis
0.000 0.165 0.835
C73 Malignant neoplasm of thyroid gland
0.000 0.166 0.834
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.169 0.831
D04.7 Skin of lower limb, including hip
0.000 0.170 0.830
L43.9 Lichen planus, unspecified
0.000 0.171 0.829
C44.0 Skin of lip
0.000 0.172 0.828
E28 Ovarian dysfunction
0.000 0.176 0.824
E11.9 Without complications
0.000 0.186 0.814
E04 Other non-toxic goitre
0.000 0.186 0.814
E29 Testicular dysfunction
0.000 0.190 0.810
E13 Other specified diabetes mellitus
0.000 0.191 0.809
D09 Carcinoma in situ of other and unspecified sites
0.000 0.194 0.806
C91 Lymphoid leukaemia
0.000 0.198 0.802
G36 Other acute disseminated demyelination
0.798 0.202 0.000
E24 Cushing's syndrome
0.000 0.203 0.797
M06.3 Rheumatoid nodule
0.000 0.206 0.794
D04.2 Skin of ear and external auricular canal
0.000 0.209 0.791
E78.5 Hyperlipidaemia, unspecified
0.000 0.210 0.790
C82.0 Small cleaved cell, follicular
0.000 0.211 0.789
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.212 0.788
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.217 0.783
D04.9 Skin, unspecified
0.000 0.217 0.783
D04.4 Skin of scalp and neck
0.000 0.219 0.781
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.224 0.776
L85 Other epidermal thickening
0.000 0.227 0.773
L42 Pityriasis rosea
0.000 0.229 0.771
M06.4 Inflammatory polyarthropathy
0.000 0.230 0.770
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.231 0.769
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.233 0.767
E10.2 With renal complications
0.000 0.235 0.765
L94 Other localised connective tissue disorders
0.000 0.236 0.764
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.237 0.763
E78.6 Lipoprotein deficiency
0.000 0.239 0.761
E23.0 Hypopituitarism
0.000 0.239 0.761
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.239 0.761
E10.6 With other specified complications
0.000 0.240 0.760
E88 Other metabolic disorders
0.000 0.245 0.755
C12 Malignant neoplasm of pyriform sinus
0.000 0.250 0.750
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.250 0.750
E26 Hyperaldosteronism
0.000 0.251 0.749
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.253 0.747
L85.8 Other specified epidermal thickening
0.000 0.253 0.747
E05.8 Other thyrotoxicosis
0.000 0.256 0.744
C83.7 Burkitt's tumour
0.000 0.256 0.743
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.256 0.744
E78.2 Mixed hyperlipidaemia
0.000 0.257 0.743
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.258 0.742
E10.8 With unspecified complications
0.000 0.258 0.741
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.259 0.741
M10 Gout
0.000 0.259 0.741
C83.1 Small cleaved cell (diffuse)
0.000 0.260 0.740
L43.8 Other lichen planus
0.000 0.261 0.739
E04.0 Non-toxic diffuse goitre
0.000 0.268 0.732
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.271 0.729
L40.4 Guttate psoriasis
0.000 0.271 0.729
E78.1 Pure hyperglyceridaemia
0.000 0.274 0.726
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.275 0.725
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.276 0.724
D03 Melanoma in situ
0.000 0.277 0.723
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.278 0.722
E03.8 Other specified hypothyroidism
0.000 0.280 0.720
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.282 0.718
C07 Malignant neoplasm of parotid gland
0.000 0.282 0.718
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.716
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.283 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.716
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.716
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.716
M05.1 Rheumatoid lung disease
0.000 0.283 0.716
M05.0 Felty's syndrome
0.000 0.283 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.288 0.712
E32 Diseases of thymus
0.000 0.288 0.712
E31 Polyglandular dysfunction
0.000 0.288 0.712
E30 Disorders of puberty, not elsewhere classified
0.000 0.288 0.712
E11.2 With renal complications
0.000 0.288 0.712
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.289 0.711
L44 Other papulosquamous disorders
0.000 0.289 0.711
L41 Parapsoriasis
0.000 0.289 0.711
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.289 0.711
E28.2 Polycystic ovarian syndrome
0.000 0.292 0.708
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.293 0.707
C94 Other leukaemias of specified cell type
0.000 0.293 0.707
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.293 0.707
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.294 0.706
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.294 0.706
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.294 0.705
E23.1 Drug-induced hypopituitarism
0.000 0.294 0.705
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.295 0.705
C85.0 Lymphosarcoma
0.000 0.295 0.705
E11.0 With coma
0.000 0.295 0.705
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.296 0.704
C91.9 Lymphoid leukaemia, unspecified
0.000 0.296 0.704
L57.5 Actinic granuloma
0.000 0.296 0.703
L57.3 Poikiloderma of Civatte
0.000 0.296 0.703
L57.2 Cutis rhomboidalis nuchae
0.000 0.296 0.703
L57.1 Actinic reticuloid
0.000 0.296 0.703
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.297 0.703
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.298 0.702
G37.5 Concentric sclerosis [Balo]
0.701 0.299 0.000
G37.4 Subacute necrotising myelitis
0.701 0.299 0.000
G37.2 Central pontine myelinolysis
0.701 0.299 0.000
G37.1 Central demyelination of corpus callosum
0.701 0.299 0.000
G37.0 Diffuse sclerosis
0.701 0.299 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.300 0.700
D04.8 Skin of other sites
0.000 0.301 0.699
D04.0 Skin of lip
0.000 0.301 0.699
L94.2 Calcinosis cutis
0.000 0.302 0.698
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.303 0.697
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.303 0.697
D06.0 Endocervix
0.000 0.304 0.696
L55 Sunburn
0.000 0.304 0.696
E11.1 With ketoacidosis
0.000 0.306 0.694
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.307 0.693
C82.2 Large cell, follicular
0.000 0.307 0.693
D06.7 Other parts of cervix
0.000 0.308 0.692
D06.1 Exocervix
0.000 0.308 0.692
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.308 0.692
E84 Cystic fibrosis
0.000 0.309 0.691
M06.8 Other specified rheumatoid arthritis
0.000 0.310 0.690
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.310 0.690
C86 Other specified types of T/NK-cell lymphoma
0.000 0.311 0.689
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.311 0.689
C83.6 Undifferentiated (diffuse)
0.000 0.312 0.687
C83.5 Lymphoblastic (diffuse)
0.000 0.312 0.687
C83.4 Immunoblastic (diffuse)
0.000 0.312 0.687
C83.2 Mixed small and large cell (diffuse)
0.000 0.312 0.687
C93 Monocytic leukaemia
0.000 0.313 0.687
C03 Malignant neoplasm of gum
0.000 0.314 0.686
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.319 0.681
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.320 0.680
E03.1 Congenital hypothyroidism without goitre
0.000 0.320 0.680
E29.1 Testicular hypofunction
0.000 0.322 0.678
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.322 0.678
C02.9 Tongue, unspecified
0.000 0.322 0.678
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.326 0.674
E13.9 Without complications
0.000 0.328 0.671
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.329 0.671
E20 Hypoparathyroidism
0.000 0.330 0.670
D43.0 Brain, supratentorial
0.000 0.331 0.669
C04 Malignant neoplasm of floor of mouth
0.000 0.331 0.669
M12 Other specific arthropathies
0.000 0.331 0.669
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.333 0.667
C90.2 Plasmacytoma, extramedullary
0.000 0.334 0.666
C02.1 Border of tongue
0.000 0.335 0.665
G36.0 Neuromyelitis optica [Devic]
0.665 0.335 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.663 0.337 0.000
E25 Adrenogenital disorders
0.000 0.338 0.662
C43.4 Malignant melanoma of scalp and neck
0.000 0.339 0.661
E79 Disorders of purine and pyrimidine metabolism
0.000 0.340 0.659
E11.8 With unspecified complications
0.000 0.341 0.659
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.341 0.659
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.342 0.658
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.343 0.657
E27.9 Disorder of adrenal gland, unspecified
0.000 0.343 0.656
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.344 0.656
D09.0 Bladder
0.000 0.344 0.656
C81 Hodgkin's disease
0.000 0.345 0.655
E11.7 With multiple complications
0.000 0.345 0.655
L43.3 Subacute (active) lichen planus
0.000 0.345 0.654
L43.2 Lichenoid drug reaction
0.000 0.345 0.654
L43.1 Bullous lichen planus
0.000 0.345 0.654
L43.0 Hypertrophic lichen planus
0.000 0.345 0.654
D04.6 Skin of upper limb, including shoulder
0.000 0.346 0.654
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.347 0.653
C11 Malignant neoplasm of nasopharynx
0.000 0.347 0.652
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.350 0.650
E04.9 Non-toxic goitre, unspecified
0.000 0.350 0.650
E77 Disorders of glycoprotein metabolism
0.000 0.351 0.649
E76 Disorders of glycosaminoglycan metabolism
0.000 0.351 0.649
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.351 0.649
E70 Disorders of aromatic amino-acid metabolism
0.000 0.351 0.649
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.351 0.649
C88 Malignant immunoproliferative diseases
0.000 0.352 0.647
E27.5 Adrenomedullary hyperfunction
0.000 0.355 0.645
E27.0 Other adrenocortical overactivity
0.000 0.355 0.645
C82.6 Cutaneous follicle centre lymphoma
0.000 0.358 0.642
C82.5 Diffuse follicle centre lymphoma
0.000 0.358 0.642
C82.4 Follicular lymphoma grade IIIb
0.000 0.358 0.642
E06.5 Other chronic thyroiditis
0.000 0.359 0.641
E06.4 Drug-induced thyroiditis
0.000 0.359 0.641
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.359 0.641
E06.0 Acute thyroiditis
0.000 0.359 0.641
C43.8 Overlapping malignant melanoma of skin
0.000 0.361 0.639
C43.0 Malignant melanoma of lip
0.000 0.361 0.639
L58 Radiodermatitis
0.000 0.362 0.638
E88.8 Other specified metabolic disorders
0.000 0.362 0.638
C95 Leukaemia of unspecified cell type
0.000 0.364 0.635
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.365 0.634
E10.4 With neurological complications
0.000 0.367 0.633
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.367 0.633
D01.0 Colon
0.000 0.367 0.633
M05.2 Rheumatoid vasculitis
0.000 0.370 0.629
C91.5 Adult T-cell leukaemia
0.000 0.373 0.627
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.377 0.623
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.378 0.622
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.378 0.621
M11 Other crystal arthropathies
0.000 0.379 0.621
C13 Malignant neoplasm of hypopharynx
0.000 0.380 0.620
L94.0 Localised scleroderma [morphea]
0.000 0.383 0.617
E04.2 Non-toxic multinodular goitre
0.000 0.383 0.617
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.386 0.614
D09.1 Other and unspecified urinary organs
0.000 0.387 0.613
E88.3 Tumour lysis syndrome
0.000 0.388 0.612
D04.1 Skin of eyelid, including canthus
0.000 0.388 0.612
E78.4 Other hyperlipidaemia
0.000 0.388 0.612
C91.4 Hairy-cell leukaemia
0.000 0.389 0.611
E89.0 Postprocedural hypothyroidism
0.000 0.390 0.610
E06.9 Thyroiditis, unspecified
0.000 0.390 0.610
E24.0 Pituitary-dependent Cushing's disease
0.000 0.390 0.610
C84.5 Other and unspecified T-cell lymphomas
0.000 0.391 0.609
E24.9 Cushing's syndrome, unspecified
0.000 0.392 0.608
D03.5 Melanoma in situ of trunk
0.000 0.393 0.607
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.396 0.604
D46 Myelodysplastic syndromes
0.000 0.396 0.604
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.397 0.603
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.397 0.603
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.397 0.603
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.397 0.603
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.397 0.603
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.397 0.603
L10-L14 Bullous disorders
0.000 0.397 0.603
M10.0 Idiopathic gout
0.000 0.398 0.602
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.399 0.600
L80 Vitiligo
0.000 0.400 0.600
L87 Transepidermal elimination disorders
0.000 0.400 0.600
L86 Keratoderma in diseases classified elsewhere
0.000 0.400 0.600
M06.34 Rheumatoid nodule (Hand)
0.000 0.400 0.600
L57.4 Cutis laxa senilis
0.000 0.400 0.599
C91.0 Acute lymphoblastic leukaemia
0.000 0.401 0.599
M14 Arthropathies in other diseases classified elsewhere
0.000 0.404 0.595
E24.2 Drug-induced Cushing's syndrome
0.000 0.405 0.595
C43.9 Malignant melanoma of skin, unspecified
0.000 0.405 0.595
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.406 0.594
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.407 0.593
E80.4 Gilbert's syndrome
0.000 0.408 0.592
E27.8 Other specified disorders of adrenal gland
0.000 0.408 0.592
C90.3 Solitary plasmacytoma
0.000 0.409 0.591
L81 Other disorders of pigmentation
0.000 0.409 0.591
E28.9 Ovarian dysfunction, unspecified
0.000 0.409 0.590
E28.8 Other ovarian dysfunction
0.000 0.409 0.590
E28.1 Androgen excess
0.000 0.409 0.590
E28.0 Oestrogen excess
0.000 0.409 0.590
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.409 0.590
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.412 0.588
E74 Other disorders of carbohydrate metabolism
0.000 0.412 0.588
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.413 0.586
E04.8 Other specified non-toxic goitre
0.000 0.416 0.584
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.417 0.583
E29.9 Testicular dysfunction, unspecified
0.000 0.419 0.581
E29.8 Other testicular dysfunction
0.000 0.419 0.581
E29.0 Testicular hyperfunction
0.000 0.419 0.581
E13.8 With unspecified complications
0.000 0.420 0.580
E13.7 With multiple complications
0.000 0.420 0.580
E13.6 With other specified complications
0.000 0.420 0.580
E13.5 With peripheral circulatory complications
0.000 0.420 0.580
E13.4 With neurological complications
0.000 0.420 0.580
E13.3 With ophthalmic complications
0.000 0.420 0.580
E13.2 With renal complications
0.000 0.420 0.580
E13.1 With ketoacidosis
0.000 0.420 0.580
E13.0 With coma
0.000 0.420 0.580
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.420 0.580
E28.3 Primary ovarian failure
0.000 0.421 0.579
D09.9 Carcinoma in situ, unspecified
0.000 0.422 0.578
D09.7 Carcinoma in situ of other specified sites
0.000 0.422 0.578
D09.3 Thyroid and other endocrine glands
0.000 0.422 0.578
D09.2 Eye
0.000 0.422 0.578
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.423 0.577
C00 Malignant neoplasm of lip
0.000 0.424 0.576
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.424 0.576
E11.6 With other specified complications
0.000 0.424 0.576
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.425 0.575
C91.7 Other lymphoid leukaemia
0.000 0.425 0.575
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.425 0.575
C91.3 Prolymphocytic leukaemia
0.000 0.425 0.575
C91.2 Subacute lymphocytic leukaemia
0.000 0.425 0.575
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.425 0.575
E78.3 Hyperchylomicronaemia
0.000 0.425 0.574
E26.0 Primary hyperaldosteronism
0.000 0.426 0.574
L92.0 Granuloma annulare
0.000 0.426 0.574
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.427 0.573
E88.9 Metabolic disorder, unspecified
0.000 0.427 0.572
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.428 0.572
G36.9 Acute disseminated demyelination, unspecified
0.572 0.428 0.000
G36.8 Other specified acute disseminated demyelination
0.572 0.428 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.572 0.428 0.000
E24.8 Other Cushing's syndrome
0.000 0.428 0.571
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.428 0.571
E24.3 Ectopic ACTH syndrome
0.000 0.428 0.571
E24.1 Nelson's syndrome
0.000 0.428 0.571
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.430 0.570
M06.38 Rheumatoid nodule (Other)
0.000 0.430 0.570
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.430 0.570
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.430 0.570
M06.33 Rheumatoid nodule (Forearm)
0.000 0.430 0.570
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.430 0.570
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.430 0.570
C82.3 Follicular lymphoma grade IIIa
0.000 0.431 0.568
D00.1 Oesophagus
0.000 0.435 0.565
L56.3 Solar urticaria
0.000 0.435 0.565
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.435 0.565
L56.1 Drug photoallergic response
0.000 0.435 0.565
L56.0 Drug phototoxic response
0.000 0.435 0.565
C60-C63 Malignant neoplasms of male genital organs
0.000 0.435 0.565
D47.2 Monoclonal gammopathy
0.000 0.437 0.563
E88.2 Lipomatosis, not elsewhere classified
0.000 0.438 0.562
C03.1 Lower gum
0.000 0.439 0.560
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.440 0.560
L94.8 Other specified localised connective tissue disorders
0.000 0.441 0.559
C84.4 Peripheral T-cell lymphoma
0.000 0.442 0.558
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.443 0.557
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.444 0.555
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.445 0.555
L85.3 Xerosis cutis
0.000 0.446 0.554
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.446 0.554
L85.0 Acquired ichthyosis
0.000 0.446 0.554
C05 Malignant neoplasm of palate
0.000 0.447 0.553
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.448 0.552
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.448 0.552
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.448 0.552
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.448 0.552
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.448 0.552
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.448 0.552
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.448 0.552
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.448 0.552
C74 Malignant neoplasm of adrenal gland
0.000 0.448 0.552
D01.3 Anus and anal canal
0.000 0.449 0.551
C02.8 Overlapping lesion of tongue
0.000 0.450 0.550
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.450 0.550
C02.2 Ventral surface of tongue
0.000 0.450 0.550
C02.0 Dorsal surface of tongue
0.000 0.450 0.550
E89.2 Postprocedural hypoparathyroidism
0.000 0.451 0.549
L94.6 Ainhum
0.000 0.452 0.548
L94.5 Poikiloderma vasculare atrophicans
0.000 0.452 0.548
L94.4 Gottron's papules
0.000 0.452 0.548
L94.3 Sclerodactyly
0.000 0.452 0.548
L94.1 Linear scleroderma
0.000 0.452 0.548
E89.3 Postprocedural hypopituitarism
0.000 0.452 0.548
C08.9 Major salivary gland, unspecified
0.000 0.452 0.547
E73 Lactose intolerance
0.000 0.453 0.546
D01.9 Digestive organ, unspecified
0.000 0.454 0.546
D01.7 Other specified digestive organs
0.000 0.454 0.546
D01.5 Liver, gallbladder and bile ducts
0.000 0.454 0.546
D01.4 Other and unspecified parts of intestine
0.000 0.454 0.546
D01.1 Rectosigmoid junction
0.000 0.454 0.546
L83 Acanthosis nigricans
0.000 0.456 0.544
L81.4 Other melanin hyperpigmentation
0.000 0.456 0.544
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.457 0.542
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.458 0.542
E72 Other disorders of amino-acid metabolism
0.000 0.458 0.542
D43.2 Brain, unspecified
0.000 0.460 0.540
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.460 0.540
D47.1 Chronic myeloproliferative disease
0.000 0.461 0.539
E26.9 Hyperaldosteronism, unspecified
0.000 0.463 0.537
E26.8 Other hyperaldosteronism
0.000 0.463 0.537
E26.1 Secondary hyperaldosteronism
0.000 0.463 0.537
E89.4 Postprocedural ovarian failure
0.000 0.463 0.537
E84.9 Cystic fibrosis, unspecified
0.000 0.463 0.537
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.466 0.534
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.467 0.533
E78.8 Other disorders of lipoprotein metabolism
0.000 0.467 0.533
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.468 0.532
E89.5 Postprocedural testicular hypofunction
0.000 0.468 0.532
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.468 0.531
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.468 0.531
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.468 0.531
C84.3 Lymphoepithelioid lymphoma
0.000 0.468 0.531
C84.2 T-zone lymphoma
0.000 0.468 0.531
C84.1 Sezary's diease
0.000 0.468 0.531
L93 Lupus erythematosus
0.000 0.468 0.531
M10.4 Other secondary gout
0.000 0.469 0.531
M10.2 Drug-induced gout
0.000 0.469 0.531
M10.1 Lead-induced gout
0.000 0.469 0.531
L56.4 Polymorphous light eruption
0.000 0.469 0.531
D43.4 Spinal cord
0.000 0.471 0.529
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.472 0.528
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.475 0.525
C04.9 Floor of mouth, unspecified
0.000 0.479 0.521
E40-E46 Malnutrition
0.000 0.479 0.520
D00.2 Stomach
0.000 0.480 0.520
D03.9 Melanoma in situ, unspecified
0.000 0.482 0.518
D03.8 Melanoma in situ of other sites
0.000 0.482 0.518

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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