TreeWAS – Variant ID: rs185158884

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.950	0.050
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.950	0.050
S80-S89 Injuries to the knee and lower leg	0.923	0.077
Chapter XV Pregnancy, childbirth and the puerperium	0.922	0.078
Chapter XX External causes of morbidity and mortality	0.920	0.080
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.911	0.089
Chapter X Diseases of the respiratory system	0.904	0.096
S82 Fracture of lower leg, including ankle	0.893	0.107
J30-J39 Other diseases of upper respiratory tract	0.892	0.108
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.890	0.110
Chapter VI Diseases of the nervous system	0.886	0.114
M20-M25 Other joint disorders	0.878	0.122
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.877	0.123
J34 Other disorders of nose and nasal sinuses	0.874	0.126
O60-O75 Complications of labour and delivery	0.857	0.143
S60-S69 Injuries to the wrist and hand	0.855	0.145
Chapter VIII Diseases of the ear and mastoid process	0.850	0.150
M45-M49 Spondylopathies	0.839	0.161
M25 Other joint disorders, not elsewhere classified	0.838	0.161
J34.2 Deviated nasal septum	0.837	0.163
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.833	0.167
Chapter XIV Diseases of the genitourinary system	0.830	0.170
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.826	0.174
G40-G47 Episodic and paroxysmal disorders	0.816	0.184
M25.7 Osteophyte	0.815	0.185
S82.8 Fractures of other parts of lower leg	0.809	0.191
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.794	0.206
Y83.2 Surgical operation with anastomosis, bypass or graft	0.793	0.207
V20-V29 Motorcycle rider injured in transport accident	0.789	0.211
N17-N19 Renal failure	0.788	0.212
G90-G99 Other disorders of the nervous system	0.788	0.212
S82.6 Fracture of lateral malleolus	0.787	0.213
T81 Complications of procedures, not elsewhere classified	0.782	0.218
M48 Other spondylopathies	0.780	0.220
O20-O29 Other maternal disorders predominantly related to pregnancy	0.775	0.225
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.775	0.225
J00-J06 Acute upper respiratory infections	0.775	0.225
J34.8 Other specified disorders of nose and nasal sinuses	0.774	0.226
Chapter I Certain infectious and parasitic diseases	0.769	0.231
J95-J99 Other diseases of the respiratory system	0.765	0.235
S40-S49 Injuries to the shoulder and upper arm	0.758	0.242
S20-S29 Injuries to the thorax	0.756	0.244
M25.76 Osteophyte (Lower leg)	0.755	0.245
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.754	0.246
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.753	0.247
G40 Epilepsy	0.751	0.249
S82.80 Fractures of other parts of lower leg (closed)	0.750	0.250
H80-H83 Diseases of inner ear	0.749	0.251
M25.77 Osteophyte (Ankle and foot)	0.747	0.253
M50-M54 Other dorsopathies	0.746	0.254
N17 Acute renal failure	0.740	0.260
S62 Fracture at wrist and hand level	0.739	0.261
M48.0 Spinal stenosis	0.738	0.262
S70-S79 Injuries to the hip and thigh	0.737	0.263
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.735	0.265
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.731	0.269
G43 Migraine	0.728	0.272
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.717	0.283
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.714	0.286
S82.60 Fracture of lateral malleolus (closed)	0.712	0.288
O73 Retained placenta and membranes, without haemorrhage	0.707	0.293
M24 Other specific joint derangements	0.706	0.294
N17.9 Acute renal failure, unspecified	0.706	0.294
W20-W49 Exposure to inanimate mechanical forces	0.703	0.297
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.701	0.299
Y84.8 Other medical procedures	0.700	0.300
O32 Maternal care for known or suspected malpresentation of foetus	0.700	0.300
S82.5 Fracture of medial malleolus	0.695	0.305
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.695	0.305
N70-N77 Inflammatory diseases of female pelvic organs	0.694	0.306
S82.1 Fracture of upper end of tibia	0.693	0.307
S66 Injury of muscle and tendon at wrist and hand level	0.688	0.312
Chapter XXII Codes for special purposes	0.681	0.319
Chapter XVI Certain conditions originating in the perinatal period	0.681	0.319
T79-T79 Certain early complications of trauma	0.681	0.319
T66-T78 Other and unspecified effects of external causes	0.681	0.319
T33-T35 Frostbite	0.681	0.319
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.681	0.319
T26-T28 Burns and corrosions confined to eye and internal organs	0.681	0.319
T20-T25 Burns and corrosions of external body surface, specified by site	0.681	0.319
T15-T19 Effects of foreign body entering through natural orifice	0.681	0.319
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.681	0.319
T00-T07 Injuries involving multiple body regions	0.681	0.319
S90-S99 Injuries to the ankle and foot	0.681	0.319
S10-S19 Injuries to the neck	0.681	0.319
O48 Prolonged pregnancy	0.677	0.323
Y83.3 Surgical operation with formation of external stoma	0.677	0.323
O70 Perineal laceration during delivery	0.675	0.325
O72 Postpartum haemorrhage	0.674	0.326
A30-A49 Other bacterial diseases	0.673	0.327
J33 Nasal polyp	0.672	0.328
O43 Placental disorders	0.671	0.329
O69 Labour and delivery complicated by umbilical cord complications	0.669	0.331
M40-M43 Deforming dorsopathies	0.668	0.332
J36 Peritonsillar abscess	0.668	0.332
S00-S09 Injuries to the head	0.667	0.333
O94-O99 Other obstetric conditions, not elsewhere classified	0.666	0.333
T88 Other complications of surgical and medical care, not elsewhere classified	0.666	0.334
J98 Other respiratory disorders	0.665	0.334
M31 Other necrotising vasculopathies	0.665	0.335
G43.9 Migraine, unspecified	0.664	0.336
M35 Other systemic involvement of connective tissue	0.664	0.336
J34.3 Hypertrophy of nasal turbinates	0.663	0.337
V10-V19 Pedal cyclist injured in transport accident	0.662	0.338
J32 Chronic sinusitis	0.662	0.338
O26 Maternal care for other conditions predominantly related to pregnancy	0.662	0.338
S89 Other and unspecified injuries of lower leg	0.661	0.338
S88 Traumatic amputation of lower leg	0.661	0.338
S87 Crushing injury of lower leg	0.661	0.338
S86 Injury of muscle and tendon at lower leg level	0.661	0.338
S85 Injury of blood vessels at lower leg level	0.661	0.338
S84 Injury of nerves at lower leg level	0.661	0.338
S81 Open wound of lower leg	0.661	0.338
S80 Superficial injury of lower leg	0.661	0.338
G80-G83 Cerebral palsy and other paralytic syndromes	0.661	0.338
O85-O92 Complications predominantly related to the puerperium	0.661	0.339
G93 Other disorders of brain	0.661	0.339
T81.8 Other complications of procedures, not elsewhere classified	0.660	0.340
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.659	0.341
Y35-Y36 Legal intervention and operations of war	0.659	0.341
Y10-Y34 Event of undetermined intent	0.659	0.341
Y00-Y09 Assault	0.659	0.341
X85-X99 Assault	0.659	0.341
X60-X84 Intentional self-harm	0.659	0.341
X58-X59 Accidental exposure to other and unspecified factors	0.659	0.341
X50-X57 Overexertion, travel and privation	0.659	0.341
X40-X49 Accidental poisoning by and exposure to noxious substances	0.659	0.341
X30-X39 Exposure to forces of nature	0.659	0.341
X20-X29 Contact with venomous animals and plants	0.659	0.341
X10-X19 Contact with heat and hot substances	0.659	0.341
X00-X09 Exposure to smoke, fire and flames	0.659	0.341
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.659	0.341
W75-W84 Other accidental threats to breathing	0.659	0.341
W65-W74 Accidental drowning and submersion	0.659	0.341
W50-W64 Exposure to animate mechanical forces	0.659	0.341
V98-V99 Other and unspecified transport accidents	0.659	0.341
V95-V97 Air and space transport accidents	0.659	0.341
V90-V94 Water transport accidents	0.659	0.341
V80-V89 Other land transport accidents	0.659	0.341
V70-V79 Bus occupant injured in transport accident	0.659	0.341
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.659	0.341
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.659	0.341
V40-V49 Car occupant injured in transport accident	0.659	0.341
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.659	0.341
V01-V09 Pedestrian injured in transport accident	0.659	0.341
M80-M85 Disorders of bone density and structure	0.658	0.341
J00 Acute nasopharyngitis [common cold]	0.658	0.342
M20 Acquired deformities of fingers and toes	0.656	0.344
Chapter VII Diseases of the eye and adnexa	0.656	0.344
J39 Other diseases of upper respiratory tract	0.655	0.345
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.655	0.345
H90-H95 Other disorders of ear	0.655	0.345
O64 Obstructed labour due to malposition and malpresentation of foetus	0.654	0.346
Y60-Y69 Misadventures to patients during surgical and medical care	0.654	0.346
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.653	0.346
M91-M94 Chondropathies	0.653	0.346
M86-M90 Other osteopathies	0.653	0.346
M60-M63 Disorders of muscles	0.653	0.346
M00-M03 Infectious arthropathies	0.653	0.346
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.653	0.347
N25-N29 Other disorders of kidney and ureter	0.653	0.347
Y83.9 Surgical procedure, unspecified	0.653	0.347
T36-T50 Poisoning by drugs, medicaments and biological substances	0.650	0.350
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.650	0.350
H81 Disorders of vestibular function	0.649	0.350
J30 Vasomotor and allergic rhinitis	0.649	0.351
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.648	0.351
Y83.4 Other reconstructive surgery	0.647	0.353
Y84.0 Cardiac catheterisation	0.647	0.353
G30-G32 Other degenerative diseases of the nervous system	0.647	0.353
G20-G26 Extrapyramidal and movement disorders	0.647	0.353
O63 Long labour	0.646	0.354
G95 Other diseases of spinal cord	0.646	0.354
O30 Multiple gestation	0.644	0.356
M05-M14 Inflammatory polyarthropathies	0.642	0.358
N60-N64 Disorders of breast	0.642	0.358
Chapter IV Endocrine, nutritional and metabolic diseases	0.641	0.359
M48.06 Spinal stenosis (Lumbar region)	0.640	0.360
S82.9 Fracture of lower leg, part unspecified	0.640	0.360
S82.7 Multiple fractures of lower leg	0.640	0.360
S82.4 Fracture of fibula alone	0.640	0.360
S82.3 Fracture of lower end of tibia	0.640	0.360
S82.2 Fracture of shaft of tibia	0.640	0.360
S82.0 Fracture of patella	0.640	0.360
J37 Chronic laryngitis and laryngotracheitis	0.639	0.361
O80-O84 Delivery	0.639	0.361
H65-H75 Diseases of middle ear and mastoid	0.637	0.363
M54 Dorsalgia	0.636	0.364
T85 Complications of other internal prosthetic devices, implants and grafts	0.636	0.364
G70-G73 Diseases of myoneural junction and muscle	0.635	0.365
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.635	0.365
G00-G09 Inflammatory diseases of the central nervous system	0.635	0.365
J09-J18 Influenza and pneumonia	0.635	0.365
M48.02 Spinal stenosis (Cervical region)	0.635	0.365
S61 Open wound of wrist and hand	0.635	0.365
J35 Chronic diseases of tonsils and adenoids	0.634	0.366
S83.2 Tear of meniscus, current	0.633	0.367
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.633	0.367
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.632	0.368
J80-J84 Other respiratory diseases principally affecting the interstitium	0.631	0.368
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.630	0.370
M34 Systemic sclerosis	0.630	0.370
M33 Dermatopolymyositis	0.630	0.370
M32 Systemic lupus erythematosus	0.630	0.370
M30 Polyarteritis nodosa and related conditions	0.630	0.370
M21 Other acquired deformities of limbs	0.630	0.370
T87 Complications peculiar to reattachment and amputation	0.629	0.371
T86 Failure and rejection of transplanted organs and tissues	0.629	0.371
T80 Complications following infusion, transfusion and therapeutic injection	0.629	0.371
S68 Traumatic amputation of wrist and hand	0.628	0.372
V23.4 Driver injured in traffic accident	0.628	0.372
N00-N08 Glomerular diseases	0.627	0.373
J34.1 Cyst and mucocele of nose and nasal sinus	0.627	0.373
J34.0 Abscess, furuncle and carbuncle of nose	0.627	0.373
N10-N16 Renal tubulo-interstitial diseases	0.621	0.379
S42 Fracture of shoulder and upper arm	0.620	0.380
N18 Chronic renal failure	0.620	0.380
M46 Other inflammatory spondylopathies	0.619	0.381
O68 Labour and delivery complicated by foetal stress [distress]	0.618	0.381
S22 Fracture of rib(s), sternum and thoracic spine	0.617	0.383
B90-B94 Sequelae of infectious and parasitic diseases	0.617	0.383
O75 Other complications of labour and delivery, not elsewhere classified	0.614	0.386
O74 Complications of anaesthesia during labour and delivery	0.614	0.386
O71 Other obstetric trauma	0.614	0.386
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.614	0.386
O66 Other obstructed labour	0.614	0.386
O65 Obstructed labour due to maternal pelvic abnormality	0.614	0.386
O62 Abnormalities of forces of labour	0.614	0.386
O61 Failed induction of labour	0.614	0.386
O60 Preterm delivery	0.614	0.386
Q38-Q45 Other congenital malformations of the digestive system	0.614	0.386
M22 Disorders of patella	0.614	0.386
J60-J70 Lung diseases due to external agents	0.613	0.387
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.613	0.387
S69 Other and unspecified injuries of wrist and hand	0.613	0.387
S67 Crushing injury of wrist and hand	0.613	0.387
S65 Injury of blood vessels at wrist and hand level	0.613	0.387
S64 Injury of nerves at wrist and hand level	0.613	0.387
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.613	0.387
S60 Superficial injury of wrist and hand	0.613	0.387
H60-H62 Diseases of external ear	0.612	0.388
D70-D77 Other diseases of blood and blood-forming organs	0.611	0.389
M47 Spondylosis	0.611	0.389
T81.3 Disruption of operation wound, not elsewhere classified	0.611	0.389
J06 Acute upper respiratory infections of multiple and unspecified sites	0.610	0.390
O32.1 Maternal care for breech presentation	0.610	0.390
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.609	0.390
M48.07 Spinal stenosis (Lumbosacral region)	0.609	0.391
Y83.6 Removal of other organ (partial) (total)	0.607	0.393
S50-S59 Injuries to the elbow and forearm	0.606	0.394
N19 Unspecified renal failure	0.605	0.394
G40.9 Epilepsy, unspecified	0.605	0.395
A41 Other septicaemia	0.605	0.395
Q20-Q28 Congenital malformations of the circulatory system	0.604	0.396
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.604	0.396
T81.4 Infection following a procedure, not elsewhere classified	0.603	0.397
O00-O08 Pregnancy with abortive outcome	0.602	0.398
M49 Spondylopathies in diseases classified elsewhere	0.601	0.399
M45 Ankylosing spondylitis	0.601	0.399
M25.9 Joint disorder, unspecified	0.601	0.399
M25.8 Other specified joint disorders	0.601	0.399
M25.6 Stiffness of joint, not elsewhere classified	0.601	0.399
M25.3 Other instability of joint	0.601	0.399
M25.2 Flail joint	0.601	0.399
M25.1 Fistula of joint	0.601	0.399
M25.0 Haemarthrosis	0.601	0.399
S62.8 Fracture of other and unspecified parts of wrist and hand	0.600	0.400
O73.0 Retained placenta, without haemorrhage	0.600	0.400
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.599	0.401
S62.6 Fracture of other finger	0.599	0.401
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.599	0.401
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.598	0.401
J98.1 Pulmonary collapse	0.598	0.402
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.597	0.402
Y83.1 Surgical operation with implant of artificial internal device	0.598	0.402
Y83.5 Amputation of limb(s)	0.597	0.402
Y83.0 Surgical operation with transplant of whole organ	0.597	0.402
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.596	0.404
O47 False labour	0.593	0.407
O45 Premature separation of placenta [abruptio placentae]	0.592	0.408
O44 Placenta praevia	0.592	0.408
O42 Premature rupture of membranes	0.592	0.408
O41 Other disorders of amniotic fluid and membranes	0.592	0.408
O35 Maternal care for known or suspected foetal abnormality and damage	0.592	0.408
O33 Maternal care for known or suspected disproportion	0.592	0.408
O31 Complications specific to multiple gestation	0.592	0.408
O40 Polyhydramnios	0.592	0.408
N40-N51 Diseases of male genital organs	0.592	0.408
G91 Hydrocephalus	0.590	0.410
O70.1 Second degree perineal laceration during delivery	0.588	0.412
J31.0 Chronic rhinitis	0.587	0.413
M65-M68 Disorders of synovium and tendon	0.586	0.414
M25.4 Effusion of joint	0.585	0.414
G46 Vascular syndromes of brain in cerebrovascular diseases	0.585	0.415
G44 Other headache syndromes	0.585	0.415
G41 Status epilepticus	0.585	0.415
M25.79 Osteophyte (Site unspecified)	0.584	0.416
M25.78 Osteophyte (Other)	0.584	0.416
M25.75 Osteophyte (Pelvic region and thigh)	0.584	0.416
M25.74 Osteophyte (Hand)	0.584	0.416
M25.73 Osteophyte (Forearm)	0.584	0.416
M25.72 Osteophyte (Upper arm)	0.584	0.416
M25.71 Osteophyte (Shoulder region)	0.584	0.416
M25.70 Osteophyte (Multiple sites)	0.584	0.416
O46 Antepartum haemorrhage, not elsewhere classified	0.582	0.418
M24.1 Other articular cartilage disorders	0.582	0.418
T92 Sequelae of injuries of upper limb	0.581	0.419
S82.86 Maisonneuve's fracture	0.580	0.420
S82.81 Fractures of other parts of lower leg (open)	0.580	0.420
S79 Other and unspecified injuries of hip and thigh	0.578	0.422
H80 Otosclerosis	0.578	0.422
M25.5 Pain in joint	0.577	0.423
N99-N99 Other disorders of the genitourinary system	0.576	0.424
Y44 Agents primarily affecting blood constituents	0.575	0.425
M23 Internal derangement of knee	0.574	0.426
Y52 Agents primarily affecting the cardiovascular system	0.573	0.427
O20 Haemorrhage in early pregnancy	0.572	0.428
W00-W19 Falls	0.570	0.430
G93.3 Postviral fatigue syndrome	0.570	0.430
M54.9 Dorsalgia, unspecified	0.570	0.430
Y84.9 Medical procedure, unspecified	0.570	0.430
Y84.7 Blood-sampling	0.570	0.430
Y84.6 Urinary catheterisation	0.570	0.430
Y84.5 Insertion of gastric or duodenal sound	0.570	0.430
Y84.4 Aspiration of fluid	0.570	0.430
Y84.3 Shock therapy	0.570	0.430
Y84.1 Kidney dialysis	0.570	0.430
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.569	0.431
G99 Other disorders of nervous system in diseases classified elsewhere	0.569	0.431
M20.1 Hallux valgus (acquired)	0.567	0.433
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.567	0.433
V29 Motorcycle rider injured in other and unspecified transport accidents	0.565	0.434
V28 Motorcycle rider injured in noncollision transport accident	0.565	0.434
V27 Motorcycle rider injured in collision with fixed or stationary object	0.565	0.434
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.565	0.434
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.565	0.434
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.565	0.434
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.565	0.434
V21 Motorcycle rider injured in collision with pedal cycle	0.565	0.434
V20 Motorcycle rider injured in collision with pedestrian or animal	0.565	0.434
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.565	0.435
G96 Other disorders of central nervous system	0.565	0.435
G94 Other disorders of brain in diseases classified elsewhere	0.565	0.435
G90 Disorders of autonomic nervous system	0.565	0.435
G98 Other disorders of nervous system, not elsewhere classified	0.565	0.435
G92 Toxic encephalopathy	0.565	0.435
A41.9 Septicaemia, unspecified	0.565	0.435
S82.61 Fracture of lateral malleolus (open)	0.565	0.435
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.564	0.436
B35-B49 Mycoses	0.562	0.438
T81.9 Unspecified complication of procedure	0.561	0.439
T81.7 Vascular complications following a procedure, not elsewhere classified	0.561	0.439
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.561	0.439
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.561	0.439
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.561	0.439
O43.1 Malformation of placenta	0.560	0.440
M48.9 Spondylopathy, unspecified	0.559	0.441
M48.8 Other specified spondylopathies	0.559	0.441
M48.5 Collapsed vertebra, not elsewhere classified	0.559	0.441
M48.4 Fatigue fracture of vertebra	0.559	0.441
M48.3 Traumatic spondylopathy	0.559	0.441
M48.2 Kissing spine	0.559	0.441
M48.1 Ankylosing hyperostosis [Forestier]	0.559	0.441
H83 Other diseases of inner ear	0.557	0.443
N72 Inflammatory disease of cervix uteri	0.556	0.444
O29 Complications of anaesthesia during pregnancy	0.556	0.444
O28 Abnormal findings on antenatal screening of mother	0.556	0.444
O24 Diabetes mellitus in pregnancy	0.556	0.444
O23 Infections of genito-urinary tract in pregnancy	0.556	0.444
O22 Venous complications in pregnancy	0.556	0.444
O21 Excessive vomiting in pregnancy	0.556	0.444
O25 Malnutrition in pregnancy	0.556	0.444
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.556	0.444
Q80-Q89 Other congenital malformations	0.556	0.444
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.556	0.444
Q60-Q64 Congenital malformations of the urinary system	0.556	0.444
Q50-Q56 Congenital malformations of genital organs	0.556	0.444
Q35-Q37 Cleft lip and cleft palate	0.556	0.444
Q30-Q34 Congenital malformations of the respiratory system	0.556	0.444
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.556	0.444
Q00-Q07 Congenital malformations of the nervous system	0.556	0.444
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.555	0.444
J04 Acute laryngitis and tracheitis	0.555	0.444
J03 Acute tonsillitis	0.555	0.444
J01 Acute sinusitis	0.555	0.444
S00 Superficial injury of head	0.554	0.446
B95-B98 Bacterial, viral and other infectious agents	0.554	0.446
S82.50 Fracture of medial malleolus (closed)	0.553	0.447
O63.0 Prolonged first stage (of labour)	0.553	0.447
M35.0 Sicca syndrome [Sjogren]	0.553	0.447
O26.8 Other specified pregnancy-related conditions	0.553	0.447
S62.3 Fracture of other metacarpal bone	0.552	0.448
B99-B99 Other infectious diseases	0.551	0.449
B85-B89 Pediculosis, acariasis and other infestations	0.551	0.449
B65-B83 Helminthiases	0.551	0.449
B50-B64 Protozoal diseases	0.551	0.449
B20-B24 Human immunodeficiency virus [HIV] disease	0.551	0.449
B15-B19 Viral hepatitis	0.551	0.449
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.551	0.449
A80-A89 Viral infections of the central nervous system	0.551	0.449
A75-A79 Rickettsioses	0.551	0.449
A70-A74 Other diseases caused by chlamydiae	0.551	0.449
A65-A69 Other spirochaetal diseases	0.551	0.449
A50-A64 Infections with a predominantly sexual mode of transmission	0.551	0.449
A20-A28 Certain zoonotic bacterial diseases	0.551	0.449
A15-A19 Tuberculosis	0.551	0.449
S82.10 Fracture of upper end of tibia (closed)	0.550	0.450
J99 Respiratory disorders in diseases classified elsewhere	0.549	0.451
J96 Respiratory failure, not elsewhere classified	0.549	0.451
J95 Postprocedural respiratory disorders, not elsewhere classified	0.549	0.451
W29 Contact with other powered hand tools and household machinery	0.548	0.452
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.547	0.452
E70-E90 Metabolic disorders	0.548	0.452
Y84.2 Radiological procedure and radiotherapy	0.546	0.453
H00 Hordeolum and chalazion	0.546	0.454
M51 Other intervertebral disk disorders	0.546	0.454
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.545	0.454
G95.2 Cord compression, unspecified	0.544	0.456
S49 Other and unspecified injuries of shoulder and upper arm	0.544	0.456
S48 Traumatic amputation of shoulder and upper arm	0.544	0.456
S46 Injury of muscle and tendon at shoulder and upper arm level	0.544	0.456
S45 Injury of blood vessels at shoulder and upper arm level	0.544	0.456
S44 Injury of nerves at shoulder and upper arm level	0.544	0.456
S41 Open wound of shoulder and upper arm	0.544	0.456
S40 Superficial injury of shoulder and upper arm	0.544	0.456
S47 Crushing injury of shoulder and upper arm	0.544	0.456
O72.1 Other immediate postpartum haemorrhage	0.542	0.458
S29 Other and unspecified injuries of thorax	0.542	0.458
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.542	0.458
S27 Injury of other and unspecified intrathoracic organs	0.542	0.458
S26 Injury of heart	0.542	0.458
S25 Injury of blood vessels of thorax	0.542	0.458
S24 Injury of nerves and spinal cord at thorax level	0.542	0.458
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.542	0.458
S21 Open wound of thorax	0.542	0.458
S20 Superficial injury of thorax	0.542	0.458
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.542	0.458
J02 Acute pharyngitis	0.542	0.458
H81.2 Vestibular neuronitis	0.541	0.459
S83.7 Injury to multiple structures of knee	0.540	0.460
S83.6 Sprain and strain of other and unspecified parts of knee	0.540	0.460
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.540	0.460
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.540	0.460
S83.3 Tear of articular cartilage of knee, current	0.540	0.460
S83.1 Dislocation of knee	0.540	0.460
S83.0 Dislocation of patella	0.540	0.460
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.540	0.460
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.540	0.460
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.540	0.460
T82.4 Mechanical complication of vascular dialysis catheter	0.540	0.460
T82.3 Mechanical complication of other vascular grafts	0.540	0.460
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.540	0.460
T82.1 Mechanical complication of cardiac electronic device	0.540	0.460
T82.0 Mechanical complication of heart valve prosthesis	0.540	0.460
D80-D89 Certain disorders involving the immune mechanism	0.539	0.461
G40.8 Other epilepsy	0.538	0.461
G40.7 Petit mal, unspecified, without grand mal seizures	0.538	0.461
G40.5 Special epileptic syndromes	0.538	0.461
G40.4 Other generalised epilepsy and epileptic syndromes	0.538	0.461
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.538	0.461
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.538	0.461
B25-B34 Other viral diseases	0.538	0.462
S61.1 Open wound of finger(s) with damage to nail	0.538	0.462
O36 Maternal care for other known or suspected foetal problems	0.537	0.463
H82 Vertiginous syndromes in diseases classified elsewhere	0.537	0.463
S72 Fracture of femur	0.536	0.464
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.536	0.464
M53 Other dorsopathies, not elsewhere classified	0.535	0.465
O69.1 Labour and delivery complicated by cord around neck, with compression	0.534	0.466
G35-G37 Demyelinating diseases of the central nervous system	0.531	0.469
N17.8 Other acute renal failure	0.531	0.469
N17.2 Acute renal failure with medullary necrosis	0.531	0.469
N17.1 Acute renal failure with acute cortical necrosis	0.531	0.469
N17.0 Acute renal failure with tubular necrosis	0.531	0.469
S62.7 Multiple fractures of fingers	0.530	0.470
S62.5 Fracture of thumb	0.530	0.470
S62.4 Multiple fractures of metacarpal bones	0.530	0.470
S62.2 Fracture of first metacarpal bone	0.530	0.470
S62.1 Fracture of other carpal bone(s)	0.530	0.470
S62.0 Fracture of navicular [scaphoid] bone of hand	0.530	0.470
M48.09 Spinal stenosis (Site unspecified)	0.529	0.471
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.529	0.471
M48.05 Spinal stenosis (Thoracolumbar region)	0.529	0.471
M48.04 Spinal stenosis (Thoracic region)	0.529	0.471
M48.03 Spinal stenosis (Cervicothoracic region)	0.529	0.471
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.529	0.471
M48.00 Spinal stenosis (Multiple sites in spine)	0.529	0.471
N20-N23 Urolithiasis	0.529	0.471
H81.1 Benign paroxysmal vertigo	0.529	0.471
J33.9 Nasal polyp, unspecified	0.529	0.471
H90 Conductive and sensorineural hearing loss	0.529	0.471
S78 Traumatic amputation of hip and thigh	0.528	0.472
S77 Crushing injury of hip and thigh	0.528	0.472
S76 Injury of muscle and tendon at hip and thigh level	0.528	0.472
S75 Injury of blood vessels at hip and thigh level	0.528	0.472
S74 Injury of nerves at hip and thigh level	0.528	0.472
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.528	0.472
S71 Open wound of hip and thigh	0.528	0.472
S70 Superficial injury of hip and thigh	0.528	0.472
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.528	0.472

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations