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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1854853
log Bayes Factor = 4.215
Chromosome 6   position 167,533,062  (GRCh37) Explore rs1854853 on Ensembl!
Variant rs1854853 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.065 0.935
E00-E07 Disorders of thyroid gland
0.000 0.115 0.885
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.124 0.876
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.130 0.870
E03.8 Other specified hypothyroidism
0.000 0.162 0.838
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.237 0.763
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.286 0.714
E14.9 Without complications
0.000 0.288 0.712
E14 Unspecified diabetes mellitus
0.000 0.291 0.709
E10-E14 Diabetes mellitus
0.000 0.310 0.690
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.313 0.687
E03.1 Congenital hypothyroidism without goitre
0.000 0.326 0.674
E03.5 Myxoedema coma
0.000 0.330 0.670
E03.4 Atrophy of thyroid (acquired)
0.000 0.330 0.670
E03.3 Postinfectious hypothyroidism
0.000 0.330 0.670
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.365 0.635
E00 Congenital iodine-deficiency syndrome
0.000 0.365 0.635
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.371 0.629
E05.5 Thyroid crisis or storm
0.000 0.372 0.628
E05.4 Thyrotoxicosis factitia
0.000 0.372 0.628
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.372 0.628
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.372 0.628
E14.3 With ophthalmic complications
0.000 0.376 0.624
E05.9 Thyrotoxicosis, unspecified
0.000 0.403 0.597
E14.1 With ketoacidosis
0.000 0.411 0.589
E16 Other disorders of pancreatic internal secretion
0.000 0.412 0.588
E13 Other specified diabetes mellitus
0.000 0.429 0.571
E16.2 Hypoglycaemia, unspecified
0.000 0.430 0.570
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.437 0.563
E07 Other disorders of thyroid
0.000 0.441 0.559
E14.4 With neurological complications
0.000 0.443 0.557
E14.6 With other specified complications
0.000 0.463 0.537
E14.5 With peripheral circulatory complications
0.000 0.465 0.534
E14.7 With multiple complications
0.000 0.492 0.508
E14.0 With coma
0.000 0.492 0.508
E13.9 Without complications
0.000 0.500 0.500
E12 Malnutrition-related diabetes mellitus
0.000 0.505 0.495
E14.8 With unspecified complications
0.000 0.524 0.476
E14.2 Withrenal complications
0.000 0.529 0.471
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.545 0.455
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.545 0.455
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.545 0.455
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.545 0.455
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.545 0.455
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.545 0.455
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.545 0.455
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.545 0.455
E15 Nondiabetic hypoglycaemic coma
0.000 0.549 0.451
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.555 0.444
E10 Insulin-dependent diabetes mellitus
0.000 0.560 0.440
E16.1 Other hypoglycaemia
0.000 0.567 0.433
E10.9 Without complications
0.000 0.577 0.423
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.578 0.421
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.578 0.421
E16.4 Abnormal secretion of gastrin
0.000 0.578 0.421
E16.3 Increased secretion of glucagon
0.000 0.578 0.421
E13.8 With unspecified complications
0.000 0.590 0.410
E13.7 With multiple complications
0.000 0.590 0.410
E13.6 With other specified complications
0.000 0.590 0.410
E13.5 With peripheral circulatory complications
0.000 0.590 0.410
E13.4 With neurological complications
0.000 0.590 0.410
E13.2 With renal complications
0.000 0.590 0.410
E13.1 With ketoacidosis
0.000 0.590 0.410
E13.0 With coma
0.000 0.590 0.410
E40-E46 Malnutrition
0.000 0.590 0.409
E50-E64 Other nutritional deficiencies
0.000 0.598 0.402
E07.1 Dyshormogenetic goitre
0.000 0.599 0.401
E07.0 Hypersecretion of calcitonin
0.000 0.599 0.401
E07.9 Disorder of thyroid, unspecified
0.000 0.607 0.393
E06 Thyroiditis
0.000 0.615 0.385
E05.8 Other thyrotoxicosis
0.001 0.616 0.383
E13.3 With ophthalmic complications
0.000 0.621 0.379
E61 Deficiency of other nutrient elements
0.000 0.642 0.358
E12.9 Without complications
0.000 0.645 0.355
E12.8 With unspecified complications
0.000 0.645 0.355
E12.7 With multiple complications
0.000 0.645 0.355
E12.6 With other specified complications
0.000 0.645 0.355
E12.5 With peripheral circulatory complications
0.000 0.645 0.355
E12.4 With neurological complications
0.000 0.645 0.355
E12.3 With ophthalmic complications
0.000 0.645 0.355
E12.2 With renal complications
0.000 0.645 0.355
E12.1 With ketoacidosis
0.000 0.645 0.355
E12.0 With coma
0.000 0.645 0.355
E10.7 With multiple complications
0.000 0.646 0.354
E10.1 With ketoacidosis
0.000 0.656 0.344
E07.8 Other specified disorders of thyroid
0.000 0.664 0.336
E61.1 Iron deficiency
0.000 0.665 0.335
E58 Dietary calcium deficiency
0.000 0.677 0.323
E06.1 Subacute thyroiditis
0.000 0.690 0.309
E51 Thiamine deficiency
0.000 0.700 0.300
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.703 0.296
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.706 0.294
E45 Retarded development following protein-energy malnutrition
0.000 0.706 0.294
E43 Unspecified severe protein-energy malnutrition
0.000 0.706 0.294
E42 Marasmic kwashiorkor
0.000 0.706 0.294
E41 Nutritional marasmus
0.000 0.706 0.294
E40 Kwashiorkor
0.000 0.706 0.294
E10.4 With neurological complications
0.000 0.710 0.290
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.711 0.288
E50 Vitamin A deficiency
0.000 0.711 0.288
E60 Dietary zinc deficiency
0.000 0.711 0.288
E59 Dietary selenium deficiency
0.000 0.711 0.288
E52 Niacin deficiency [pellagra]
0.000 0.711 0.288
E10.0 With coma
0.000 0.713 0.287
E06.4 Drug-induced thyroiditis
0.000 0.723 0.276
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.723 0.276
E06.0 Acute thyroiditis
0.000 0.723 0.276
E63 Other nutritional deficiencies
0.000 0.726 0.274
E10.2 With renal complications
0.000 0.726 0.274
E10.6 With other specified complications
0.000 0.727 0.273
E06.5 Other chronic thyroiditis
0.000 0.732 0.267
E56 Other vitamin deficiencies
0.000 0.733 0.266
E61.9 Deficiency of nutrient element, unspecified
0.000 0.743 0.257
E61.8 Deficiency of other specified nutrient elements
0.000 0.743 0.257
E61.7 Deficiency of multiple nutrient elements
0.000 0.743 0.257
E61.6 Vanadium deficiency
0.000 0.743 0.257
E61.5 Molybdenum deficiency
0.000 0.743 0.257
E61.4 Chromium deficiency
0.000 0.743 0.257
E61.3 Manganese deficiency
0.000 0.743 0.257
E61.0 Copper deficiency
0.000 0.743 0.257
E10.8 With unspecified complications
0.000 0.752 0.248
E04 Other non-toxic goitre
0.000 0.758 0.242
E54 Ascorbic acid deficiency
0.000 0.758 0.241
E51.2 Wernicke's encephalopathy
0.000 0.773 0.227
E61.2 Magnesium deficiency
0.000 0.781 0.219
E51.9 Thiamine deficiency, unspecified
0.000 0.784 0.215
E51.8 Other manifestations of thiamine deficiency
0.000 0.784 0.215
E51.1 Beriberi
0.000 0.784 0.215
E65-E68 Obesity and other hyperalimentation
0.000 0.789 0.211
E44.1 Mild protein-energy malnutrition
0.000 0.789 0.211
E44.0 Moderate protein-energy malnutrition
0.000 0.789 0.211
E46 Unspecified protein-energy malnutrition
0.000 0.790 0.210
E50.9 Vitamin A deficiency, unspecified
0.000 0.793 0.207
E50.8 Other manifestations of vitamin A deficiency
0.000 0.793 0.207
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.793 0.207
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.793 0.207
E50.5 Vitamin A deficiency with night blindness
0.000 0.793 0.207
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.793 0.207
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.793 0.207
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.793 0.207
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.793 0.207
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.793 0.207
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.793 0.207
E64.8 Sequelae of other nutritional deficiencies
0.000 0.793 0.207
E64.3 Sequelae of rickets
0.000 0.793 0.207
E64.2 Sequelae of vitamin C deficiency
0.000 0.793 0.207
E64.1 Sequelae of vitamin A deficiency
0.000 0.793 0.207
E64.0 Sequelae of protein-energy malnutrition
0.000 0.793 0.207
E63.8 Other specified nutritional deficiencies
0.000 0.803 0.196
E63.1 Imbalance of constituents of food intake
0.000 0.803 0.196
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.803 0.196
E56.9 Vitamin deficiency, unspecified
0.000 0.809 0.191
E56.8 Deficiency of other vitamins
0.000 0.809 0.191
E56.0 Deficiency of vitamin E
0.000 0.809 0.191
E10.3 With ophthalmic complications
0.000 0.815 0.185
E63.9 Nutritional deficiency, unspecified
0.000 0.818 0.181
E55 Vitamin D deficiency
0.000 0.819 0.181
E04.0 Non-toxic diffuse goitre
0.000 0.819 0.181
E53 Deficiency of other B group vitamins
0.000 0.824 0.176
E04.8 Other specified non-toxic goitre
0.000 0.826 0.174
E56.1 Deficiency of vitamin K
0.000 0.831 0.169
E06.9 Thyroiditis, unspecified
0.001 0.833 0.167
E10.5 With peripheral circulatory complications
0.001 0.848 0.152
E67 Other hyperalimentation
0.000 0.848 0.152
E68 Sequelae of hyperalimentation
0.000 0.848 0.152
E06.3 Autoimmune thyroiditis
0.000 0.852 0.147
E04.9 Non-toxic goitre, unspecified
0.000 0.857 0.143
E55.0 Rickets, active
0.000 0.870 0.130
K55.2 Angiodysplasia of colon
0.128 0.872 0.000
E53.1 Pyridoxine deficiency
0.000 0.874 0.126
E53.0 Riboflavin deficiency
0.000 0.874 0.126
E53.9 Vitamin B deficiency, unspecified
0.000 0.881 0.119
E67.8 Other specified hyperalimentation
0.000 0.891 0.109
E67.3 Hypervitaminosis D
0.000 0.891 0.109
E67.2 Megavitamin-B6 syndrome
0.000 0.891 0.109
E67.1 Hypercarotenaemia
0.000 0.891 0.109
E67.0 Hypervitaminosis A
0.000 0.891 0.109
E04.2 Non-toxic multinodular goitre
0.000 0.898 0.102
K55 Vascular disorders of intestine
0.084 0.916 0.000
K55.9 Vascular disorder of intestine, unspecified
0.080 0.920 0.000
E65 Localised adiposity
0.001 0.921 0.079
E04.1 Non-toxic single thyroid nodule
0.000 0.932 0.068
K55.8 Other vascular disorders of intestine
0.063 0.937 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.939 0.061
E66 Obesity
0.000 0.943 0.057
K55.1 Chronic vascular disorders of intestine
0.056 0.944 0.000
E24 Cushing's syndrome
0.000 0.950 0.050
E29 Testicular dysfunction
0.000 0.951 0.049
E66.0 Obesity due to excess calories
0.000 0.953 0.047
K55.0 Acute vascular disorders of intestine
0.045 0.955 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.956 0.044
E32 Diseases of thymus
0.000 0.956 0.044
E30 Disorders of puberty, not elsewhere classified
0.000 0.956 0.044
E26 Hyperaldosteronism
0.000 0.956 0.044
E28 Ovarian dysfunction
0.000 0.956 0.044
E24.9 Cushing's syndrome, unspecified
0.000 0.957 0.043
E25 Adrenogenital disorders
0.000 0.958 0.042
E66.1 Drug-induced obesity
0.000 0.959 0.041
E31 Polyglandular dysfunction
0.000 0.959 0.041
E20 Hypoparathyroidism
0.000 0.960 0.040
E29.1 Testicular hypofunction
0.000 0.960 0.040
E24.2 Drug-induced Cushing's syndrome
0.000 0.962 0.038
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.962 0.038
E23 Hypofunction and other disorders of pituitary gland
0.000 0.963 0.037
E24.0 Pituitary-dependent Cushing's disease
0.000 0.963 0.037
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.964 0.036
E24.3 Ectopic ACTH syndrome
0.000 0.964 0.036
E24.1 Nelson's syndrome
0.000 0.964 0.036
E28.3 Primary ovarian failure
0.000 0.964 0.036
E29.8 Other testicular dysfunction
0.000 0.965 0.035
E29.0 Testicular hyperfunction
0.000 0.965 0.035
E26.9 Hyperaldosteronism, unspecified
0.000 0.965 0.035
E53.8 Deficiency of other specified B group vitamins
0.000 0.966 0.034
E29.9 Testicular dysfunction, unspecified
0.000 0.966 0.034
E23.0 Hypopituitarism
0.000 0.968 0.032
E30.9 Disorder of puberty, unspecified
0.000 0.968 0.032
E30.8 Other disorders of puberty
0.000 0.968 0.032
E30.1 Precocious puberty
0.000 0.968 0.032
E30.0 Delayed puberty
0.000 0.968 0.032
E32.9 Disease of thymus, unspecified
0.000 0.968 0.032
E32.8 Other diseases of thymus
0.000 0.968 0.032
E32.1 Abscess of thymus
0.000 0.968 0.032
E32.0 Persistent hyperplasia of thymus
0.000 0.968 0.032
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.968 0.032
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.968 0.032
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.968 0.032
E26.8 Other hyperaldosteronism
0.000 0.968 0.032
E26.1 Secondary hyperaldosteronism
0.000 0.968 0.032
E24.8 Other Cushing's syndrome
0.000 0.968 0.032
E28.9 Ovarian dysfunction, unspecified
0.000 0.968 0.032
E28.8 Other ovarian dysfunction
0.000 0.968 0.032
E28.1 Androgen excess
0.000 0.968 0.032
E28.0 Oestrogen excess
0.000 0.968 0.032
E25.9 Adrenogenital disorder, unspecified
0.000 0.970 0.030
E25.8 Other adrenogenital disorders
0.000 0.970 0.030
E31.9 Polyglandular dysfunction, unspecified
0.000 0.970 0.029
E31.8 Other polyglandular dysfunction
0.000 0.970 0.029
E31.1 Polyglandular hyperfunction
0.000 0.970 0.029
E20.8 Other hypoparathyroidism
0.000 0.971 0.029
E20.1 Pseudohypoparathyroidism
0.000 0.971 0.029
E20.0 Idiopathic hypoparathyroidism
0.000 0.971 0.029
E26.0 Primary hyperaldosteronism
0.000 0.971 0.028
E23.7 Disorder of pituitary gland, unspecified
0.000 0.972 0.028
C43.5 Malignant melanoma of trunk
0.028 0.972 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.972 0.028
E23.1 Drug-induced hypopituitarism
0.000 0.973 0.027
E31.0 Autoimmune polyglandular failure
0.000 0.974 0.026
E20.9 Hypoparathyroidism, unspecified
0.000 0.975 0.025
E27 Other disorders of adrenal gland
0.000 0.975 0.025
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.975 0.024
E28.2 Polycystic ovarian syndrome
0.000 0.976 0.024
E34 Other endocrine disorders
0.000 0.976 0.024
E22 Hyperfunction of pituitary gland
0.000 0.977 0.023
E55.9 Vitamin D deficiency, unspecified
0.001 0.977 0.022
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.977 0.023
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.979 0.021
E89.0 Postprocedural hypothyroidism
0.000 0.980 0.020
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.981 0.019
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.981 0.019
E23.6 Other disorders of pituitary gland
0.000 0.981 0.019
E21.2 Other hyperparathyroidism
0.000 0.981 0.018
E27.5 Adrenomedullary hyperfunction
0.000 0.982 0.018
E27.0 Other adrenocortical overactivity
0.000 0.982 0.018
E70-E90 Metabolic disorders
0.000 0.982 0.018
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.982 0.018
E34.5 Androgen resistance syndrome
0.000 0.982 0.017
E34.4 Constitutional tall stature
0.000 0.982 0.017
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.982 0.017
E34.1 Other hypersecretion of intestinal hormones
0.000 0.982 0.017
E34.9 Endocrine disorder, unspecified
0.000 0.983 0.017
E22.8 Other hyperfunction of pituitary gland
0.000 0.983 0.017
E21.4 Other specified disorders of parathyroid gland
0.000 0.983 0.016
E34.3 Short stature, not elsewhere classified
0.000 0.984 0.016
E66.8 Other obesity
0.000 0.984 0.016
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.984 0.015
E22.0 Acromegaly and pituitary gigantism
0.000 0.984 0.015
E23.2 Diabetes insipidus
0.000 0.985 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.985 0.015
E34.8 Other specified endocrine disorders
0.000 0.985 0.014
E27.2 Addisonian crisis
0.000 0.985 0.014
E89.2 Postprocedural hypoparathyroidism
0.000 0.986 0.014
E79 Disorders of purine and pyrimidine metabolism
0.000 0.986 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.986 0.014
E22.1 Hyperprolactinaemia
0.000 0.986 0.013
E72 Other disorders of amino-acid metabolism
0.000 0.986 0.013
E76 Disorders of glycosaminoglycan metabolism
0.000 0.987 0.013
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.987 0.013
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.987 0.013
E89.5 Postprocedural testicular hypofunction
0.000 0.987 0.013
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.987 0.013
E84 Cystic fibrosis
0.000 0.987 0.013
E27.8 Other specified disorders of adrenal gland
0.000 0.987 0.013
E89.1 Postprocedural hypoinsulinaemia
0.000 0.987 0.013
E70 Disorders of aromatic amino-acid metabolism
0.000 0.987 0.013
E27.9 Disorder of adrenal gland, unspecified
0.000 0.987 0.012
E77 Disorders of glycoprotein metabolism
0.000 0.987 0.012
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.988 0.012
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.988 0.012
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.988 0.012
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.988 0.012
E89.4 Postprocedural ovarian failure
0.000 0.988 0.012
E74 Other disorders of carbohydrate metabolism
0.000 0.988 0.011
T78.4 Allergy, unspecified
0.011 0.989 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.989 0.011
E75.5 Other lipid storage disorders
0.000 0.989 0.011
E72.0 Disorders of amino-acid transport
0.000 0.989 0.011
E80.2 Other porphyria
0.000 0.989 0.011
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.989 0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.989 0.011
E88 Other metabolic disorders
0.000 0.989 0.011
T78 Adverse effects, not elsewhere classified
0.011 0.989 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.010 0.990 0.000
E85 Amyloidosis
0.000 0.990 0.010
E34.0 Carcinoid syndrome
0.001 0.990 0.009
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.990 0.010
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.990 0.010
E79.1 Lesch-Nyhan syndrome
0.000 0.990 0.010
E75.6 Lipid storage disorder, unspecified
0.000 0.990 0.010
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.990 0.010
E75.3 Sphingolipidosis, unspecified
0.000 0.990 0.010
E75.1 Other gangliosidosis
0.000 0.990 0.010
E75.0 GM2 gangliosidosis
0.000 0.990 0.010
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.990 0.010
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.990 0.010
E72.5 Disorders of glycine metabolism
0.000 0.990 0.010
E72.4 Disorders of ornithine metabolism
0.000 0.990 0.010
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.990 0.010
E72.2 Disorders of urea cycle metabolism
0.000 0.990 0.010
E71.3 Disorders of fatty-acid metabolism
0.000 0.990 0.010
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.990 0.010
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.990 0.010
E71.0 Maple-syrup-urine disease
0.000 0.990 0.010
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.990 0.010
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.990 0.010
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.990 0.010
E76.2 Other mucopolysaccharidoses
0.000 0.990 0.010
E76.1 Mucopolysaccharidosis, type II
0.000 0.990 0.010
E76.0 Mucopolysaccharidosis, type I
0.000 0.990 0.010
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.990 0.010
E73 Lactose intolerance
0.000 0.990 0.009
E84.8 Cystic fibrosis with other manifestations
0.000 0.990 0.010
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.990 0.010
Q27.3 Peripheral arteriovenous malformation
0.010 0.990 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.010 0.990 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.990 0.009
E84.9 Cystic fibrosis, unspecified
0.000 0.991 0.009
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.991 0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.991 0.009
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.991 0.009
E70.2 Disorders of tyrosine metabolism
0.000 0.991 0.009
E70.1 Other hyperphenylalaninaemias
0.000 0.991 0.009
E70.0 Classical phenylketonuria
0.000 0.991 0.009
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.991 0.009
E77.1 Defects in glycoprotein degradation
0.000 0.991 0.009
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.991 0.009
E75.2 Other sphingolipidosis
0.000 0.991 0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.991 0.009
E80.5 Crigler-Najjar syndrome
0.000 0.991 0.009
E80.3 Defects of catalase and peroxydase
0.000 0.991 0.009
E80.0 Hereditary erythropoietic porphyria
0.000 0.991 0.009
E21.0 Primary hyperparathyroidism
0.000 0.991 0.009
E70.3 Albinism
0.000 0.991 0.008
T78.9 Adverse effect, unspecified
0.009 0.991 0.000
E88.8 Other specified metabolic disorders
0.000 0.991 0.009
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.991 0.008
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.991 0.008
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.991 0.008
E74.2 Disorders of galactose metabolism
0.000 0.991 0.008
E74.1 Disorders of fructose metabolism
0.000 0.991 0.008
E77.8 Other disorders of glycoprotein metabolism
0.000 0.991 0.008
T78.3 Angioneurotic oedema
0.008 0.992 0.000
E74.0 Glycogen storage disease
0.000 0.992 0.008
E88.9 Metabolic disorder, unspecified
0.000 0.992 0.008
L50.0 Allergic urticaria
0.008 0.992 0.000
E85.4 Organ-limited amyloidosis
0.000 0.992 0.008
E80.1 Porphyria cutanea tarda
0.000 0.992 0.008
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.992 0.008
S92.70 Multiple fractures of foot (closed)
0.008 0.992 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.992 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.992 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.992 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.992 0.007
E85.8 Other amyloidosis
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.000 0.993 0.007
E73.1 Secondary lactase deficiency
0.000 0.993 0.007
E73.0 Congenital lactase deficiency
0.000 0.993 0.007
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.993 0.007
E78.1 Pure hyperglyceridaemia
0.000 0.993 0.007
O80.0 Spontaneous vertex delivery
0.007 0.993 0.000
T78.2 Anaphylactic shock, unspecified
0.007 0.993 0.000
E78.4 Other hyperlipidaemia
0.000 0.993 0.007
E80.4 Gilbert's syndrome
0.000 0.993 0.007
T78.8 Other adverse effects, not elsewhere classified
0.007 0.993 0.000
D43.2 Brain, unspecified
0.007 0.993 0.000
S92.7 Multiple fractures of foot
0.007 0.993 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.993 0.007
E85.3 Secondary systemic amyloidosis
0.000 0.993 0.006
E11 Non-insulin-dependent diabetes mellitus
0.000 0.994 0.006
C44.3 Skin of other and unspecified parts of face
0.006 0.994 0.000
H10.9 Conjunctivitis, unspecified
0.006 0.994 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.994 0.006
O81.0 Low forceps delivery
0.006 0.994 0.000
K81.9 Cholecystitis, unspecified
0.006 0.994 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.994 0.006
E78.3 Hyperchylomicronaemia
0.000 0.994 0.006
O80 Single spontaneous delivery
0.006 0.994 0.000
Q27 Other congenital malformations of peripheral vascular system
0.006 0.994 0.000
S92 Fracture of foot, except ankle
0.006 0.994 0.000
S92.40 Fracture of great toe (closed)
0.006 0.994 0.000
S92.4 Fracture of great toe
0.006 0.994 0.000
K81.0 Acute cholecystitis
0.006 0.994 0.000
E11.0 With coma
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.000 0.994 0.005
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.994 0.006
S92.30 Fracture of metatarsal bone (closed)
0.006 0.994 0.000
S92.3 Fracture of metatarsal bone
0.006 0.994 0.000
E78.6 Lipoprotein deficiency
0.000 0.994 0.005
E85.9 Amyloidosis, unspecified
0.000 0.994 0.005
O81 Single delivery by forceps and vacuum extractor
0.005 0.995 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.995 0.005
O80.8 Other single spontaneous delivery
0.005 0.995 0.000
E83 Disorders of mineral metabolism
0.000 0.995 0.005
S92.71 Multiple fractures of foot (open)
0.005 0.995 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.005 0.995 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.005 0.995 0.000
S92.5 Fracture of other toe
0.005 0.995 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.995 0.005
O81.4 Vacuum extractor delivery
0.005 0.995 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.005 0.995 0.000
S92.2 Fracture of other tarsal bone(s)
0.005 0.995 0.000
E11.7 With multiple complications
0.000 0.995 0.005
Q27.8 Other specified congenital malformations of peripheral vascular system
0.005 0.995 0.000
S92.41 Fracture of great toe (open)
0.005 0.995 0.000
Z48.8 Other specified surgical follow-up care
0.005 0.995 0.000
D46 Myelodysplastic syndromes
0.005 0.995 0.000
Q27.1 Congenital renal artery stenosis
0.004 0.995 0.000
L50 Urticaria
0.005 0.995 0.000
O80.1 Spontaneous breech delivery
0.004 0.995 0.000
Q27.4 Congenital phlebectasia
0.004 0.995 0.000
Q27.2 Other congenital malformations of renal artery
0.004 0.995 0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery
0.004 0.995 0.000
E11.6 With other specified complications
0.000 0.996 0.004
K81 Cholecystitis
0.004 0.996 0.000
D47.1 Chronic myeloproliferative disease
0.004 0.996 0.000
S92.9 Fracture of foot, unspecified
0.004 0.996 0.000
R17 Unspecified jaundice
0.004 0.996 0.000
O80-O84 Delivery
0.004 0.996 0.000
S92.31 Fracture of metatarsal bone (open)
0.004 0.996 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.000 0.996 0.004
S92.50 Fracture of other toe (closed)
0.004 0.996 0.000
H10 Conjunctivitis
0.004 0.996 0.000
S92.51 Fracture of other toe (open)
0.004 0.996 0.000
H44.2 Degenerative myopia
0.004 0.996 0.000
O80.9 Single spontaneous delivery, unspecified
0.004 0.996 0.000
D43.1 Brain, infratentorial
0.004 0.996 0.000
O81.5 Delivery by combination of forceps and vacuum extractor
0.004 0.996 0.000
O81.2 Mid-cavity forceps with rotation
0.004 0.996 0.000
O81.1 Mid-cavity forceps delivery
0.004 0.996 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.996 0.004
E83.8 Other disorders of mineral metabolism
0.000 0.996 0.004
E83.2 Disorders of zinc metabolism
0.000 0.996 0.004
E83.0 Disorders of copper metabolism
0.000 0.996 0.004
S92.20 Fracture of other tarsal bone(s) (closed)
0.004 0.996 0.000
D46.4 Refractory anaemia, unspecified
0.004 0.996 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.004 0.996 0.000
E11.8 With unspecified complications
0.000 0.996 0.004
H10.3 Acute conjunctivitis, unspecified
0.004 0.996 0.000
Z37.2 Twins, both liveborn
0.000 0.996 0.004
Z04.3 Examination and observation following other accident
0.004 0.996 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.004 0.996 0.000
S92.1 Fracture of talus
0.004 0.996 0.000
D37.4 Colon
0.000 0.996 0.004
D43.9 Central nervous system, unspecified
0.004 0.996 0.000
D43.7 Other parts of central nervous system
0.004 0.996 0.000
D43.3 Cranial nerves
0.004 0.996 0.000
O81.3 Other and unspecified forceps delivery
0.004 0.996 0.000
M79.67 Pain in limb (Ankle and foot)
0.000 0.996 0.004
N64.1 Fat necrosis of breast
0.000 0.996 0.004
E73.9 Lactose intolerance, unspecified
0.001 0.996 0.003
S92.21 Fracture of other tarsal bone(s) (open)
0.004 0.996 0.000
D43.4 Spinal cord
0.004 0.996 0.000
D47.4 Osteomyelofibrosis
0.004 0.996 0.000
D46.1 Refractory anaemia with sideroblasts
0.004 0.996 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.004 0.996 0.000
H10.0 Mucopurulent conjunctivitis
0.003 0.996 0.000
J94.2 Haemothorax
0.004 0.996 0.000
C48.2 Peritoneum, unspecified
0.004 0.996 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.003 0.996 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.003 0.996 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.003 0.996 0.000
O83 Other assisted single delivery
0.003 0.996 0.000
D46.7 Other myelodysplastic syndromes
0.003 0.996 0.000
L50.6 Contact urticaria
0.003 0.996 0.000
L50.5 Cholinergic urticaria
0.003 0.996 0.000
L50.4 Vibratory urticaria
0.003 0.996 0.000
L50.3 Dermatographic urticaria
0.003 0.996 0.000
L50.2 Urticaria due to cold and heat
0.003 0.996 0.000
R85.7 Abnormal histological findings
0.004 0.996 0.000
C48.1 Specified parts of peritoneum
0.003 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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