TreeWAS – Variant ID: rs1861046

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter VII Diseases of the eye and adnexa	0.999	0.001
I60-I69 Cerebrovascular diseases	0.997	0.003
Chapter V Mental and behavioural disorders	0.994	0.006
Chapter XX External causes of morbidity and mortality	0.990	0.010
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.982	0.018
H53-H54 Visual disturbances and blindness	0.977	0.023
Chapter I Certain infectious and parasitic diseases	0.976	0.024
S40-S49 Injuries to the shoulder and upper arm	0.976	0.024
F10 Mental and behavioural disorders due to use of alcohol	0.973	0.027
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.971	0.029
F10.3 Withdrawal state	0.965	0.035
I70-I79 Diseases of arteries, arterioles and capillaries	0.965	0.035
H53 Visual disturbances	0.962	0.038
I30-I52 Other forms of heart disease	0.962	0.038
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.960	0.040
Chapter IV Endocrine, nutritional and metabolic diseases	0.951	0.049
Chapter X Diseases of the respiratory system	0.945	0.055
H53.9 Visual disturbance, unspecified	0.942	0.058
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.935	0.065
B35-B49 Mycoses	0.934	0.066
I69 Sequelae of cerebrovascular disease	0.930	0.070
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.927	0.072
H30-H36 Disorders of choroid and retina	0.925	0.075
I71 Aortic aneurysm and dissection	0.920	0.080
I61 Intracerebral haemorrhage	0.919	0.081
I05-I09 Chronic rheumatic heart diseases	0.911	0.089
H53.2 Diplopia	0.909	0.091
S20-S29 Injuries to the thorax	0.905	0.095
I95-I99 Other and unspecified disorders of the circulatory system	0.905	0.095
I67 Other cerebrovascular diseases	0.903	0.097
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.900	0.100
D70-D77 Other diseases of blood and blood-forming organs	0.900	0.100
J80-J84 Other respiratory diseases principally affecting the interstitium	0.897	0.103
I51 Complications and ill-defined descriptions of heart disease	0.896	0.104
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.891	0.109
J95-J99 Other diseases of the respiratory system	0.886	0.114
Y43 Primarily systemic agents	0.877	0.123
Y52 Agents primarily affecting the cardiovascular system	0.877	0.123
I74 Arterial embolism and thrombosis	0.875	0.125
S50-S59 Injuries to the elbow and forearm	0.875	0.125
I62 Other nontraumatic intracranial haemorrhage	0.869	0.131
B37 Candidiasis	0.866	0.134
I50 Heart failure	0.866	0.134
I47 Paroxysmal tachycardia	0.864	0.136
M20-M25 Other joint disorders	0.863	0.137
I63 Cerebral infarction	0.862	0.138
M25 Other joint disorders, not elsewhere classified	0.862	0.138
M25.5 Pain in joint	0.859	0.141
F30-F39 Mood [affective] disorders	0.858	0.142
S42 Fracture of shoulder and upper arm	0.852	0.148
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.850	0.150
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.849	0.151
J81 Pulmonary oedema	0.849	0.151
I95 Hypotension	0.848	0.152
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.846	0.154
I67.9 Cerebrovascular disease, unspecified	0.846	0.154
H04 Disorders of lachrymal system	0.841	0.159
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.838	0.161
X60-X84 Intentional self-harm	0.838	0.162
D75 Other diseases of blood and blood-forming organs	0.838	0.162
B37.9 Candidiasis, unspecified	0.836	0.164
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.835	0.165
Chapter XV Pregnancy, childbirth and the puerperium	0.832	0.168
I05 Rheumatic mitral valve diseases	0.832	0.168
V40-V49 Car occupant injured in transport accident	0.830	0.170
I35 Nonrheumatic aortic valve disorders	0.824	0.176
S46 Injury of muscle and tendon at shoulder and upper arm level	0.823	0.177
I51.7 Cardiomegaly	0.818	0.182
S90-S99 Injuries to the ankle and foot	0.815	0.185
Y43.3 Other antineoplastic drugs	0.814	0.186
T91 Sequelae of injuries of neck and trunk	0.813	0.187
I34 Nonrheumatic mitral valve disorders	0.813	0.187
S10-S19 Injuries to the neck	0.810	0.190
E70-E90 Metabolic disorders	0.810	0.190
H46-H48 Disorders of optic nerve and visual pathways	0.810	0.190
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.808	0.192
I47.2 Ventricular tachycardia	0.807	0.193
I61.9 Intracerebral haemorrhage, unspecified	0.807	0.193
H18 Other disorders of cornea	0.806	0.193
S51 Open wound of forearm	0.805	0.195
J90-J94 Other diseases of pleura	0.804	0.196
F10.0 Acute intoxication	0.803	0.197
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.803	0.197
B49 Unspecified mycosis	0.802	0.198
B25-B34 Other viral diseases	0.801	0.199
H16 Keratitis	0.800	0.200
M25.57 Pain in joint (Ankle and foot)	0.800	0.200
E00-E07 Disorders of thyroid gland	0.799	0.201
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.799	0.201
A30-A49 Other bacterial diseases	0.798	0.202
H35 Other retinal disorders	0.795	0.205
W00-W19 Falls	0.792	0.208
S49 Other and unspecified injuries of shoulder and upper arm	0.789	0.211
O60-O75 Complications of labour and delivery	0.789	0.211
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.788	0.212
H04.5 Stenosis and insufficiency of lachrymal passages	0.787	0.213
T93 Sequelae of injuries of lower limb	0.787	0.213
J98 Other respiratory disorders	0.786	0.214
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.786	0.214
F99-F99 Unspecified mental disorder	0.786	0.214
J95 Postprocedural respiratory disorders, not elsewhere classified	0.786	0.214
T92 Sequelae of injuries of upper limb	0.783	0.217
X40-X49 Accidental poisoning by and exposure to noxious substances	0.782	0.217
E65-E68 Obesity and other hyperalimentation	0.782	0.218
F40-F48 Neurotic, stress-related and somatoform disorders	0.782	0.218
F60-F69 Disorders of adult personality and behaviour	0.781	0.219
I95.1 Orthostatic hypotension	0.780	0.220
S70-S79 Injuries to the hip and thigh	0.780	0.220
S22 Fracture of rib(s), sternum and thoracic spine	0.778	0.222
S30 Superficial injury of abdomen, lower back and pelvis	0.778	0.222
T98 Sequelae of other and unspecified effects of external causes	0.778	0.222
Y49 Psychotropic drugs, not elsewhere classified	0.777	0.223
Chapter VIII Diseases of the ear and mastoid process	0.775	0.225
S42.0 Fracture of clavicle	0.775	0.225
J30-J39 Other diseases of upper respiratory tract	0.773	0.227
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.772	0.228
D72 Other disorders of white blood cells	0.771	0.229
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.770	0.230
I61.4 Intracerebral haemorrhage in cerebellum	0.769	0.230
M25.53 Pain in joint (Forearm)	0.769	0.231
S41 Open wound of shoulder and upper arm	0.769	0.231
H31 Other disorders of choroid	0.768	0.231
A80-A89 Viral infections of the central nervous system	0.767	0.233
H04.2 Epiphora	0.767	0.233
I35.1 Aortic (valve) insufficiency	0.765	0.235
T66-T78 Other and unspecified effects of external causes	0.764	0.236
I69.1 Sequelae of intracerebral haemorrhage	0.763	0.237
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.763	0.237
F10.2 Dependence syndrome	0.763	0.237
M25.55 Pain in joint (Pelvic region and thigh)	0.759	0.241
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.756	0.244
I63.9 Cerebral infarction, unspecified	0.756	0.244
W50-W64 Exposure to animate mechanical forces	0.755	0.245
D80-D89 Certain disorders involving the immune mechanism	0.755	0.245
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.754	0.246
B95-B98 Bacterial, viral and other infectious agents	0.753	0.247
T20-T25 Burns and corrosions of external body surface, specified by site	0.752	0.248
S20 Superficial injury of thorax	0.751	0.248
Y53 Agents primarily affecting the gastro-intestinal system	0.751	0.249
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.751	0.249
B99-B99 Other infectious diseases	0.750	0.250
S32 Fracture of lumbar spine and pelvis	0.750	0.250
T90 Sequelae of injuries of head	0.749	0.251
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.748	0.252
D75.1 Secondary polycythaemia	0.748	0.252
O68 Labour and delivery complicated by foetal stress [distress]	0.747	0.253
F11 Mental and behavioural disorders due to use of opioids	0.747	0.253
I31 Other diseases of pericardium	0.746	0.254
E40-E46 Malnutrition	0.745	0.255
I67.2 Cerebral atherosclerosis	0.744	0.256
E10-E14 Diabetes mellitus	0.742	0.258
M86-M90 Other osteopathies	0.740	0.260
H10-H13 Disorders of conjunctiva	0.740	0.260
S43.0 Dislocation of shoulder joint	0.740	0.260
J84 Other interstitial pulmonary diseases	0.739	0.261
V10-V19 Pedal cyclist injured in transport accident	0.736	0.264
M25.6 Stiffness of joint, not elsewhere classified	0.734	0.266
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.734	0.266
I51.6 Cardiovascular disease, unspecified	0.733	0.267
H33 Retinal detachments and breaks	0.733	0.267
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.732	0.268
E20-E35 Disorders of other endocrine glands	0.731	0.269
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.730	0.269
S21 Open wound of thorax	0.729	0.271
I78 Diseases of capillaries	0.727	0.273
X58-X59 Accidental exposure to other and unspecified factors	0.724	0.276
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.721	0.279
Y51 Drugs primarily affecting the autonomic nervous system	0.721	0.279
I37 Pulmonary valve disorders	0.720	0.280
I50.9 Heart failure, unspecified	0.720	0.280
E06 Thyroiditis	0.719	0.281
F80-F89 Disorders of psychological development	0.719	0.281
S42.00 Fracture of clavicle (closed)	0.719	0.281
Y57 Other and unspecified drugs and medicaments	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
I70 Atherosclerosis	0.716	0.284
H53.4 Visual field defects	0.716	0.284
I68 Cerebrovascular disorders in diseases classified elsewhere	0.715	0.285
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.715	0.285
I05.9 Mitral valve disease, unspecified	0.714	0.286
T94 Sequelae of injuries involving multiple and unspecified body regions	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
M80-M85 Disorders of bone density and structure	0.712	0.288
D60-D64 Aplastic and other anaemias	0.712	0.288
H47 Other disorders of optic [2nd] nerve and visual pathways	0.710	0.290
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.710	0.290
Y35-Y36 Legal intervention and operations of war	0.710	0.290
Y10-Y34 Event of undetermined intent	0.710	0.290
Y00-Y09 Assault	0.710	0.290
X85-X99 Assault	0.710	0.290
X50-X57 Overexertion, travel and privation	0.710	0.290
X30-X39 Exposure to forces of nature	0.710	0.290
X20-X29 Contact with venomous animals and plants	0.710	0.290
X10-X19 Contact with heat and hot substances	0.710	0.290
X00-X09 Exposure to smoke, fire and flames	0.710	0.290
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.710	0.290
W75-W84 Other accidental threats to breathing	0.710	0.290
W65-W74 Accidental drowning and submersion	0.710	0.290
V98-V99 Other and unspecified transport accidents	0.710	0.290
V95-V97 Air and space transport accidents	0.710	0.290
V90-V94 Water transport accidents	0.710	0.290
V70-V79 Bus occupant injured in transport accident	0.710	0.290
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.710	0.290
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.710	0.290
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.710	0.290
V01-V09 Pedestrian injured in transport accident	0.710	0.290
B44 Aspergillosis	0.709	0.291
M25.7 Osteophyte	0.709	0.291
H16.0 Corneal ulcer	0.709	0.291
I08 Multiple valve diseases	0.708	0.292
V48 Car occupant injured in noncollision transport accident	0.708	0.292
F10.4 Withdrawal state with delirium	0.705	0.294
D55-D59 Haemolytic anaemias	0.705	0.295
I50.0 Congestive heart failure	0.705	0.295
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.704	0.296
F18 Mental and behavioural disorders due to use of volatile solvents	0.704	0.296
F16 Mental and behavioural disorders due to use of hallucinogens	0.704	0.296
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.704	0.296
F14 Mental and behavioural disorders due to use of cocaine	0.704	0.296
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.704	0.296
I42 Cardiomyopathy	0.703	0.297
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.703	0.297
S40 Superficial injury of shoulder and upper arm	0.703	0.297
M45-M49 Spondylopathies	0.703	0.297
I05.0 Mitral stenosis	0.701	0.299
I34.1 Mitral (valve) prolapse	0.701	0.299
J09-J18 Influenza and pneumonia	0.701	0.299
S42.9 Fracture of shoulder girdle, part unspecified	0.701	0.299
I60 Subarachnoid haemorrhage	0.701	0.299
J98.0 Diseases of bronchus, not elsewhere classified	0.700	0.300
B85-B89 Pediculosis, acariasis and other infestations	0.700	0.300
B65-B83 Helminthiases	0.700	0.300
B50-B64 Protozoal diseases	0.700	0.300
B20-B24 Human immunodeficiency virus [HIV] disease	0.700	0.300
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.700	0.300
A75-A79 Rickettsioses	0.700	0.300
A70-A74 Other diseases caused by chlamydiae	0.700	0.300
A65-A69 Other spirochaetal diseases	0.700	0.300
A20-A28 Certain zoonotic bacterial diseases	0.700	0.300
A15-A19 Tuberculosis	0.700	0.300
S48 Traumatic amputation of shoulder and upper arm	0.700	0.300
S45 Injury of blood vessels at shoulder and upper arm level	0.700	0.300
S44 Injury of nerves at shoulder and upper arm level	0.700	0.300
S47 Crushing injury of shoulder and upper arm	0.700	0.300
H25-H28 Disorders of lens	0.699	0.301
F10.9 Unspecified mental and behavioural disorder	0.698	0.302
F10.8 Other mental and behavioural disorders	0.698	0.302
F10.7 Residual and late-onset psychotic disorder	0.698	0.302
F10.6 Amnesic syndrome	0.698	0.302
F10.5 Psychotic disorder	0.698	0.302
I74.9 Embolism and thrombosis of unspecified artery	0.698	0.302
I95.9 Hypotension, unspecified	0.697	0.303
I69.3 Sequelae of cerebral infarction	0.697	0.303
V20-V29 Motorcycle rider injured in transport accident	0.697	0.303
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.697	0.303
Y59 Other and unspecified vaccines and biological substances	0.696	0.304
Y58 Bacterial vaccines	0.696	0.304
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.696	0.304
Y50 Central nervous system stimulants, not elsewhere classified	0.696	0.304
Y48 Anaesthetics and therapeutic gases	0.696	0.304
Y47 Sedatives, hypnotics and antianxiety drugs	0.696	0.304
Y46 Antiepileptics and anti-Parkinsonism drugs	0.696	0.304
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.696	0.304
D73 Diseases of spleen	0.696	0.304
Y52.3 Coronary vasodilators, not elsewhere classified	0.696	0.304
Y52.4 Angiotensin-converting-enzyme inhibitors	0.696	0.304
F33 Recurrent depressive disorder	0.696	0.304
J30 Vasomotor and allergic rhinitis	0.695	0.305
B90-B94 Sequelae of infectious and parasitic diseases	0.694	0.306
H54 Blindness and low vision	0.694	0.306
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.694	0.306
I69.0 Sequelae of subarachnoid haemorrhage	0.693	0.307
T13 Other injuries of lower limb, level unspecified	0.693	0.307
B07 Viral warts	0.692	0.308
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.692	0.308
F12 Mental and behavioural disorders due to use of cannabinoids	0.691	0.309
M24 Other specific joint derangements	0.691	0.309
I50.1 Left ventricular failure	0.691	0.309
H53.6 Night blindness	0.690	0.310
H53.5 Colour vision deficiencies	0.690	0.310
H53.3 Other disorders of binocular vision	0.690	0.310
I52 Other heart disorders in diseases classified elsewhere	0.690	0.310
I48 Atrial fibrillation and flutter	0.690	0.310
I43 Cardiomyopathy in diseases classified elsewhere	0.690	0.310
I41 Myocarditis in diseases classified elsewhere	0.690	0.310
I40 Acute myocarditis	0.690	0.310
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.690	0.310
I32 Pericarditis in diseases classified elsewhere	0.690	0.310
H04.4 Chronic inflammation of lachrymal passages	0.689	0.311
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.689	0.311
H20 Iridocyclitis	0.689	0.311
I71.3 Abdominal aortic aneurysm, ruptured	0.689	0.311
Y40 Systemic antibiotics	0.688	0.312
T95 Sequelae of burns, corrosions and frostbite	0.688	0.312
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.688	0.312
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.688	0.312
T79-T79 Certain early complications of trauma	0.688	0.312
M25.54 Pain in joint (Hand)	0.688	0.312
T93.2 Sequelae of other fractures of lower limb	0.688	0.312
H36 Retinal disorders in diseases classified elsewhere	0.687	0.313
S51.9 Open wound of forearm, part unspecified	0.687	0.313
A50-A64 Infections with a predominantly sexual mode of transmission	0.687	0.313
D75.8 Other specified diseases of blood and blood-forming organs	0.686	0.314
Y86 Sequelae of other accidents	0.685	0.315
H04.3 Acute and unspecified inflammation of lachrymal passages	0.685	0.315
M25.56 Pain in joint (Lower leg)	0.684	0.316
W06 Fall involving bed	0.684	0.316
T14 Injury of unspecified body region	0.684	0.316
H43-H45 Disorders of vitreous body and globe	0.684	0.316
F31 Bipolar affective disorder	0.683	0.317
Y44 Agents primarily affecting blood constituents	0.683	0.317
J98.1 Pulmonary collapse	0.682	0.318
B37.4 Candidiasis of other urogenital sites	0.681	0.319
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.680	0.320
F17 Mental and behavioural disorders due to use of tobacco	0.680	0.320
D72.8 Other specified disorders of white blood cells	0.678	0.322
I72 Other aneurysm	0.678	0.322
Y43.1 Antineoplastic antimetabolites	0.677	0.323
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.677	0.323
H21 Other disorders of iris and ciliary body	0.676	0.324
S51.0 Open wound of elbow	0.676	0.324
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.675	0.325
J38.4 Oedema of larynx	0.675	0.325
Y60-Y69 Misadventures to patients during surgical and medical care	0.674	0.326
Y41 Other systemic anti-infectives and antiparasitics	0.673	0.327
M60-M63 Disorders of muscles	0.673	0.327
S46.0 Injury of tendon of the rotator cuff of shoulder	0.673	0.327
I46 Cardiac arrest	0.672	0.328
H04.9 Disorder of lachrymal system, unspecified	0.672	0.328
E86 Volume depletion	0.671	0.329
M25.59 Pain in joint (Site unspecified)	0.671	0.329
F41 Other anxiety disorders	0.670	0.330
B48 Other mycoses, not elsewhere classified	0.669	0.331
B47 Mycetoma	0.669	0.331
B46 Zygomycosis	0.669	0.331
B45 Cryptococcosis	0.669	0.331
B43 Chromomycosis and phaeomycotic abscess	0.669	0.331
B42 Sporotrichosis	0.669	0.331
B41 Paracoccidioidomycosis	0.669	0.331
B40 Blastomycosis	0.669	0.331
B39 Histoplasmosis	0.669	0.331
B38 Coccidioidomycosis	0.669	0.331
B36 Other superficial mycoses	0.669	0.331
H90-H95 Other disorders of ear	0.669	0.331
J95.0 Tracheostomy malfunction	0.669	0.331
I36 Nonrheumatic tricuspid valve disorders	0.668	0.331
S32.0 Fracture of lumbar vertebra	0.668	0.332
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.668	0.332
I71.0 Dissection of aorta [any part]	0.668	0.332
H18.5 Hereditary corneal dystrophies	0.667	0.333
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.667	0.333
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.667	0.333
E85 Amyloidosis	0.666	0.334
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.666	0.334
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.665	0.335
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.665	0.335
H17 Corneal scars and opacities	0.665	0.335
H15 Disorders of sclera	0.665	0.335
M21 Other acquired deformities of limbs	0.665	0.335
O72 Postpartum haemorrhage	0.665	0.335
M25.51 Pain in joint (Shoulder region)	0.665	0.335
M40-M43 Deforming dorsopathies	0.664	0.336
H32 Chorioretinal disorders in diseases classified elsewhere	0.663	0.336
H30 Chorioretinal inflammation	0.663	0.336
T15-T19 Effects of foreign body entering through natural orifice	0.663	0.337
H34 Retinal vascular occlusions	0.663	0.337
S30.1 Contusion of abdominal wall	0.662	0.338
E06.3 Autoimmune thyroiditis	0.662	0.338
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.661	0.339
Chapter XXII Codes for special purposes	0.661	0.339
A49 Bacterial infection of unspecified site	0.660	0.340
I71.8 Aortic aneurysm of unspecified site, ruptured	0.660	0.340
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.660	0.340
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.660	0.340
I71.1 Thoracic aortic aneurysm, ruptured	0.660	0.340
Chapter II Neoplasms	0.660	0.340
T91.9 Sequelae of unspecified injury of neck and trunk	0.659	0.341
V80-V89 Other land transport accidents	0.659	0.341
S80-S89 Injuries to the knee and lower leg	0.659	0.341
I61.8 Other intracerebral haemorrhage	0.659	0.341
I61.6 Intracerebral haemorrhage, multiple localised	0.659	0.341
I61.5 Intracerebral haemorrhage, intraventricular	0.659	0.341
I61.3 Intracerebral haemorrhage in brain stem	0.659	0.341
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.659	0.341
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.659	0.341
S90 Superficial injury of ankle and foot	0.659	0.341
W20-W49 Exposure to inanimate mechanical forces	0.658	0.342
I51.9 Heart disease, unspecified	0.658	0.342
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.657	0.343
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.657	0.343
E80 Disorders of porphyrin and bilirubin metabolism	0.657	0.343
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.656	0.344
F34 Persistent mood [affective] disorders	0.656	0.344
S20.8 Superficial injuries of other and unspecified parts of thorax	0.656	0.344
H18.4 Corneal degeneration	0.656	0.344
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.656	0.344
S49.9 Unspecified injury of shoulder and upper arm	0.655	0.345
E03 Other hypothyroidism	0.655	0.345
X68 Intentional self-poisoning by and exposure to pesticides	0.655	0.345
J38.7 Other diseases of larynx	0.655	0.345
D75.9 Disease of blood and blood-forming organs, unspecified	0.655	0.345
H53.1 Subjective visual disturbances	0.654	0.346
I09 Other rheumatic heart diseases	0.653	0.347
I06 Rheumatic aortic valve diseases	0.653	0.347
S46.2 Injury of muscle and tendon of other parts of biceps	0.652	0.348
S22.4 Multiple fractures of ribs	0.651	0.348
M84 Disorders of continuity of bone	0.650	0.350
B35 Dermatophytosis	0.650	0.350
I07 Rheumatic tricuspid valve diseases	0.650	0.350
J95.8 Other postprocedural respiratory disorders	0.649	0.350
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.649	0.351
S26 Injury of heart	0.649	0.351
S25 Injury of blood vessels of thorax	0.649	0.351
S24 Injury of nerves and spinal cord at thorax level	0.649	0.351
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.649	0.351
I99 Other and unspecified disorders of circulatory system	0.649	0.351
S52 Fracture of forearm	0.649	0.351
M25.77 Osteophyte (Ankle and foot)	0.648	0.351
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.648	0.352
T98.1 Sequelae of other and unspecified effects of external causes	0.648	0.352
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.648	0.352
H04.8 Other disorders of lachrymal system	0.647	0.353
I67.7 Cerebral arteritis, not elsewhere classified	0.647	0.353
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.647	0.353
I67.5 Moyamoya disease	0.647	0.353
I67.4 Hypertensive encephalopathy	0.647	0.353
I67.3 Progressive vascular leukoencephalopathy	0.647	0.353
I67.0 Dissection of cerebral arteries, nonruptured	0.647	0.353
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.646	0.354
F00-F09 Organic, including symptomatic, mental disorders	0.646	0.354
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.645	0.355
S37 Injury of urinary and pelvic organs	0.645	0.355
S36 Injury of intra-abdominal organs	0.645	0.355
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.645	0.355
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.645	0.355
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.645	0.355
S31 Open wound of abdomen, lower back and pelvis	0.645	0.355
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.645	0.355
D74 Methaemoglobinaemia	0.645	0.355
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.645	0.355
D71 Functional disorders of polymorphonuclear neutrophils	0.645	0.355
J94 Other pleural conditions	0.645	0.355
D86 Sarcoidosis	0.644	0.356
M25.0 Haemarthrosis	0.644	0.356
E87 Other disorders of fluid, electrolyte and acid-base balance	0.644	0.356
J82 Pulmonary eosinophilia, not elsewhere classified	0.643	0.357
T91.1 Sequelae of fracture of spine	0.642	0.358
I51.5 Myocardial degeneration	0.642	0.358
I51.4 Myocarditis, unspecified	0.642	0.358
I51.3 Intracardiac thrombosis, not elsewhere classified	0.642	0.358
I51.2 Rupture of papillary muscle, not elsewhere classified	0.642	0.358
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.642	0.358
I51.0 Cardiac septal defect, acquired	0.642	0.358
D70 Agranulocytosis	0.642	0.358
I35.2 Aortic (valve) stenosis with insufficiency	0.642	0.358
I51.8 Other ill-defined heart diseases	0.641	0.359
I47.9 Paroxysmal tachycardia, unspecified	0.640	0.360
X78 Intentional self-harm by sharp object	0.640	0.360
Y49.2 Other and unspecified antidepressants	0.638	0.362
M89 Other disorders of bone	0.638	0.362
M91-M94 Chondropathies	0.637	0.362
B25 Cytomegaloviral disease	0.637	0.363
S51.8 Open wound of other parts of forearm	0.637	0.363
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.637	0.363
F99 Mental disorder, not otherwise specified	0.636	0.364
A40 Streptococcal septicaemia	0.636	0.364
H35.0 Background retinopathy and retinal vascular changes	0.636	0.364
T91.3 Sequelae of injury of spinal cord	0.635	0.364
J96 Respiratory failure, not elsewhere classified	0.635	0.365
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.635	0.365
J60-J70 Lung diseases due to external agents	0.635	0.365
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.634	0.366
O64 Obstructed labour due to malposition and malpresentation of foetus	0.634	0.366
M31 Other necrotising vasculopathies	0.634	0.366
W13 Fall from, out of or through building or structure	0.634	0.366
O66 Other obstructed labour	0.634	0.366
H40-H42 Glaucoma	0.634	0.366
S70 Superficial injury of hip and thigh	0.633	0.367
E65 Localised adiposity	0.633	0.367
I30 Acute pericarditis	0.632	0.368
S42.4 Fracture of lower end of humerus	0.632	0.368
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.630	0.370
J98.5 Diseases of mediastinum, not elsewhere classified	0.629	0.371
F41.2 Mixed anxiety and depressive disorder	0.629	0.371
S12 Fracture of neck	0.629	0.371
Y43.9 Primarily systemic agent, unspecified	0.629	0.371
Y43.8 Other primarily systemic agents, not elsewhere classified	0.629	0.371
Y43.6 Enzymes, not elsewhere classified	0.629	0.371
Y43.5 Acidifying and alkalising agents	0.629	0.371
Y43.2 Antineoplastic natural products	0.629	0.371
Y43.0 Antiallergic and antiemetic drugs	0.629	0.371
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.629	0.371

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations