TreeWAS – Variant ID: rs1861050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
I30-I52 Other forms of heart disease	0.998	0.002
Chapter XX External causes of morbidity and mortality	0.995	0.005
Chapter X Diseases of the respiratory system	0.993	0.007
Chapter I Certain infectious and parasitic diseases	0.992	0.008
I60-I69 Cerebrovascular diseases	0.982	0.018
Chapter IV Endocrine, nutritional and metabolic diseases	0.980	0.020
S40-S49 Injuries to the shoulder and upper arm	0.974	0.026
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.973	0.027
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.972	0.028
B35-B49 Mycoses	0.966	0.034
J80-J84 Other respiratory diseases principally affecting the interstitium	0.964	0.036
I50 Heart failure	0.960	0.040
Chapter VII Diseases of the eye and adnexa	0.959	0.041
J95-J99 Other diseases of the respiratory system	0.948	0.052
E70-E90 Metabolic disorders	0.946	0.054
I47 Paroxysmal tachycardia	0.940	0.060
I95-I99 Other and unspecified disorders of the circulatory system	0.938	0.062
J81 Pulmonary oedema	0.935	0.065
I51 Complications and ill-defined descriptions of heart disease	0.931	0.069
Chapter VIII Diseases of the ear and mastoid process	0.924	0.076
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.922	0.078
H53-H54 Visual disturbances and blindness	0.917	0.083
A30-A49 Other bacterial diseases	0.912	0.088
B37 Candidiasis	0.903	0.097
I95 Hypotension	0.902	0.098
I35 Nonrheumatic aortic valve disorders	0.902	0.098
I70-I79 Diseases of arteries, arterioles and capillaries	0.901	0.099
H53 Visual disturbances	0.895	0.105
I69 Sequelae of cerebrovascular disease	0.893	0.107
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.892	0.108
J30-J39 Other diseases of upper respiratory tract	0.891	0.109
I47.2 Ventricular tachycardia	0.890	0.110
Y52 Agents primarily affecting the cardiovascular system	0.889	0.111
I63 Cerebral infarction	0.879	0.121
J98 Other respiratory disorders	0.878	0.122
E86 Volume depletion	0.878	0.122
I34 Nonrheumatic mitral valve disorders	0.877	0.123
Y43 Primarily systemic agents	0.876	0.124
I05-I09 Chronic rheumatic heart diseases	0.875	0.125
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.873	0.127
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.870	0.130
S50-S59 Injuries to the elbow and forearm	0.870	0.130
B37.9 Candidiasis, unspecified	0.869	0.131
I35.1 Aortic (valve) insufficiency	0.866	0.134
H53.9 Visual disturbance, unspecified	0.866	0.134
E87 Other disorders of fluid, electrolyte and acid-base balance	0.866	0.134
B49 Unspecified mycosis	0.866	0.134
S20-S29 Injuries to the thorax	0.864	0.136
B25-B34 Other viral diseases	0.862	0.138
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.861	0.139
I50.0 Congestive heart failure	0.860	0.140
I71 Aortic aneurysm and dissection	0.859	0.141
S46 Injury of muscle and tendon at shoulder and upper arm level	0.858	0.142
H53.2 Diplopia	0.858	0.142
I51.7 Cardiomegaly	0.856	0.144
I62 Other nontraumatic intracranial haemorrhage	0.855	0.145
I67 Other cerebrovascular diseases	0.846	0.154
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.842	0.158
J09-J18 Influenza and pneumonia	0.840	0.159
X40-X49 Accidental poisoning by and exposure to noxious substances	0.839	0.161
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.838	0.162
I50.9 Heart failure, unspecified	0.837	0.163
E00-E07 Disorders of thyroid gland	0.836	0.164
Chapter V Mental and behavioural disorders	0.836	0.164
T91 Sequelae of injuries of neck and trunk	0.834	0.166
D70-D77 Other diseases of blood and blood-forming organs	0.834	0.166
X60-X84 Intentional self-harm	0.832	0.168
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.832	0.168
T93 Sequelae of injuries of lower limb	0.830	0.170
J95 Postprocedural respiratory disorders, not elsewhere classified	0.827	0.173
J90-J94 Other diseases of pleura	0.827	0.173
I95.1 Orthostatic hypotension	0.826	0.174
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.826	0.174
H90-H95 Other disorders of ear	0.826	0.174
J30 Vasomotor and allergic rhinitis	0.822	0.177
S10-S19 Injuries to the neck	0.822	0.178
I31 Other diseases of pericardium	0.821	0.179
Y43.3 Other antineoplastic drugs	0.821	0.179
T85 Complications of other internal prosthetic devices, implants and grafts	0.819	0.181
V10-V19 Pedal cyclist injured in transport accident	0.818	0.182
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.818	0.182
I63.9 Cerebral infarction, unspecified	0.815	0.185
S42 Fracture of shoulder and upper arm	0.813	0.186
M25 Other joint disorders, not elsewhere classified	0.813	0.187
S41 Open wound of shoulder and upper arm	0.810	0.190
M20-M25 Other joint disorders	0.810	0.190
I61 Intracerebral haemorrhage	0.809	0.190
M25.5 Pain in joint	0.809	0.191
I95.9 Hypotension, unspecified	0.807	0.193
V40-V49 Car occupant injured in transport accident	0.805	0.195
T92 Sequelae of injuries of upper limb	0.805	0.195
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.805	0.195
J38.7 Other diseases of larynx	0.803	0.197
S32 Fracture of lumbar spine and pelvis	0.802	0.198
T66-T78 Other and unspecified effects of external causes	0.801	0.199
A49 Bacterial infection of unspecified site	0.800	0.200
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.799	0.201
I50.1 Left ventricular failure	0.797	0.203
E40-E46 Malnutrition	0.794	0.206
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.793	0.207
J98.0 Diseases of bronchus, not elsewhere classified	0.793	0.207
T90 Sequelae of injuries of head	0.792	0.208
S51 Open wound of forearm	0.792	0.208
T98 Sequelae of other and unspecified effects of external causes	0.790	0.210
I67.9 Cerebrovascular disease, unspecified	0.790	0.210
E20-E35 Disorders of other endocrine glands	0.787	0.213
I05 Rheumatic mitral valve diseases	0.786	0.214
Y00-Y09 Assault	0.782	0.218
E80 Disorders of porphyrin and bilirubin metabolism	0.781	0.219
J84 Other interstitial pulmonary diseases	0.781	0.219
E85 Amyloidosis	0.781	0.219
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.780	0.220
D75 Other diseases of blood and blood-forming organs	0.780	0.220
H80-H83 Diseases of inner ear	0.779	0.221
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.778	0.222
I74 Arterial embolism and thrombosis	0.777	0.223
E65-E68 Obesity and other hyperalimentation	0.775	0.225
H16 Keratitis	0.775	0.225
S49 Other and unspecified injuries of shoulder and upper arm	0.773	0.226
J98.1 Pulmonary collapse	0.773	0.227
S30 Superficial injury of abdomen, lower back and pelvis	0.773	0.227
H18 Other disorders of cornea	0.773	0.227
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.773	0.227
I42 Cardiomyopathy	0.773	0.227
H46-H48 Disorders of optic nerve and visual pathways	0.772	0.228
S90-S99 Injuries to the ankle and foot	0.771	0.229
H30-H36 Disorders of choroid and retina	0.771	0.229
A80-A89 Viral infections of the central nervous system	0.768	0.232
B99-B99 Other infectious diseases	0.766	0.234
I51.6 Cardiovascular disease, unspecified	0.766	0.234
W50-W64 Exposure to animate mechanical forces	0.760	0.240
J38.4 Oedema of larynx	0.760	0.240
Y49 Psychotropic drugs, not elsewhere classified	0.760	0.240
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.757	0.243
T88 Other complications of surgical and medical care, not elsewhere classified	0.754	0.246
M25.57 Pain in joint (Ankle and foot)	0.752	0.248
I37 Pulmonary valve disorders	0.751	0.249
T93.2 Sequelae of other fractures of lower limb	0.750	0.250
S70-S79 Injuries to the hip and thigh	0.749	0.251
E06 Thyroiditis	0.745	0.255
I34.1 Mitral (valve) prolapse	0.745	0.255
E87.2 Acidosis	0.745	0.255
S42.0 Fracture of clavicle	0.743	0.257
B44 Aspergillosis	0.742	0.258
T14 Injury of unspecified body region	0.740	0.260
B07 Viral warts	0.738	0.262
T20-T25 Burns and corrosions of external body surface, specified by site	0.738	0.262
T85.4 Mechanical complication of breast prosthesis and implant	0.737	0.263
J38.1 Polyp of vocal cord and larynx	0.736	0.264
Y51 Drugs primarily affecting the autonomic nervous system	0.735	0.265
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.734	0.266
F60-F69 Disorders of adult personality and behaviour	0.734	0.266
B34 Viral infection of unspecified site	0.730	0.270
X58-X59 Accidental exposure to other and unspecified factors	0.730	0.270
I47.9 Paroxysmal tachycardia, unspecified	0.728	0.272
Y57 Other and unspecified drugs and medicaments	0.728	0.272
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.728	0.272
B37.0 Candidal stomatitis	0.728	0.272
S46.0 Injury of tendon of the rotator cuff of shoulder	0.727	0.273
S31 Open wound of abdomen, lower back and pelvis	0.726	0.273
I60 Subarachnoid haemorrhage	0.726	0.274
E87.0 Hyperosmolality and hypernatraemia	0.724	0.276
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.720	0.280
Y41 Other systemic anti-infectives and antiparasitics	0.719	0.281
M86-M90 Other osteopathies	0.717	0.283
I69.1 Sequelae of intracerebral haemorrhage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S32.0 Fracture of lumbar vertebra	0.716	0.284
W20-W49 Exposure to inanimate mechanical forces	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.715	0.285
I48 Atrial fibrillation and flutter	0.715	0.285
I43 Cardiomyopathy in diseases classified elsewhere	0.715	0.285
I41 Myocarditis in diseases classified elsewhere	0.715	0.285
I40 Acute myocarditis	0.715	0.285
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.715	0.285
I32 Pericarditis in diseases classified elsewhere	0.715	0.285
E87.6 Hypokalaemia	0.715	0.285
I34.0 Mitral (valve) insufficiency	0.715	0.285
J14 Pneumonia due to Haemophilus influenzae	0.714	0.286
M25.6 Stiffness of joint, not elsewhere classified	0.714	0.286
S20 Superficial injury of thorax	0.713	0.287
Y35-Y36 Legal intervention and operations of war	0.713	0.287
Y10-Y34 Event of undetermined intent	0.713	0.287
X85-X99 Assault	0.713	0.287
X50-X57 Overexertion, travel and privation	0.713	0.287
X30-X39 Exposure to forces of nature	0.713	0.287
X20-X29 Contact with venomous animals and plants	0.713	0.287
X10-X19 Contact with heat and hot substances	0.713	0.287
X00-X09 Exposure to smoke, fire and flames	0.713	0.287
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.713	0.287
W75-W84 Other accidental threats to breathing	0.713	0.287
W65-W74 Accidental drowning and submersion	0.713	0.287
V98-V99 Other and unspecified transport accidents	0.713	0.287
V95-V97 Air and space transport accidents	0.713	0.287
V90-V94 Water transport accidents	0.713	0.287
V70-V79 Bus occupant injured in transport accident	0.713	0.287
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.713	0.287
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.713	0.287
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.713	0.287
V01-V09 Pedestrian injured in transport accident	0.713	0.287
E88 Other metabolic disorders	0.713	0.287
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.289
B65-B83 Helminthiases	0.711	0.289
B50-B64 Protozoal diseases	0.711	0.289
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.289
A75-A79 Rickettsioses	0.711	0.289
A70-A74 Other diseases caused by chlamydiae	0.711	0.289
A65-A69 Other spirochaetal diseases	0.711	0.289
A20-A28 Certain zoonotic bacterial diseases	0.711	0.289
A15-A19 Tuberculosis	0.711	0.289
Y52.3 Coronary vasodilators, not elsewhere classified	0.710	0.290
D72 Other disorders of white blood cells	0.710	0.290
J95.0 Tracheostomy malfunction	0.707	0.292
H60-H62 Diseases of external ear	0.707	0.293
E05 Thyrotoxicosis [hyperthyroidism]	0.707	0.293
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.707	0.293
M25.53 Pain in joint (Forearm)	0.706	0.294
J98.5 Diseases of mediastinum, not elsewhere classified	0.706	0.294
D75.1 Secondary polycythaemia	0.705	0.295
I68 Cerebrovascular disorders in diseases classified elsewhere	0.704	0.296
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.704	0.296
S46.2 Injury of muscle and tendon of other parts of biceps	0.704	0.296
I31.3 Pericardial effusion (noninflammatory)	0.703	0.297
A50-A64 Infections with a predominantly sexual mode of transmission	0.703	0.297
I46 Cardiac arrest	0.701	0.299
M25.55 Pain in joint (Pelvic region and thigh)	0.700	0.300
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.700	0.300
A46 Erysipelas	0.699	0.301
J38.5 Laryngeal spasm	0.699	0.301
B35 Dermatophytosis	0.699	0.301
M25.7 Osteophyte	0.698	0.302
S48 Traumatic amputation of shoulder and upper arm	0.698	0.302
S45 Injury of blood vessels at shoulder and upper arm level	0.698	0.302
S44 Injury of nerves at shoulder and upper arm level	0.698	0.302
S47 Crushing injury of shoulder and upper arm	0.698	0.302
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.698	0.302
I35.2 Aortic (valve) stenosis with insufficiency	0.698	0.302
T95 Sequelae of burns, corrosions and frostbite	0.698	0.302
T94 Sequelae of injuries involving multiple and unspecified body regions	0.698	0.302
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.698	0.302
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.698	0.302
Y59 Other and unspecified vaccines and biological substances	0.697	0.303
Y58 Bacterial vaccines	0.697	0.303
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.697	0.303
Y53 Agents primarily affecting the gastro-intestinal system	0.697	0.303
Y50 Central nervous system stimulants, not elsewhere classified	0.697	0.303
Y48 Anaesthetics and therapeutic gases	0.697	0.303
Y47 Sedatives, hypnotics and antianxiety drugs	0.697	0.303
Y46 Antiepileptics and anti-Parkinsonism drugs	0.697	0.303
S21 Open wound of thorax	0.697	0.303
Y86 Sequelae of other accidents	0.697	0.303
A41 Other septicaemia	0.696	0.304
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.695	0.304
J15 Bacterial pneumonia, not elsewhere classified	0.695	0.305
S40 Superficial injury of shoulder and upper arm	0.694	0.305
T13 Other injuries of lower limb, level unspecified	0.694	0.306
Y52.4 Angiotensin-converting-enzyme inhibitors	0.694	0.306
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.694	0.306
J30.4 Allergic rhinitis, unspecified	0.694	0.306
B20-B24 Human immunodeficiency virus [HIV] disease	0.693	0.306
V20-V29 Motorcycle rider injured in transport accident	0.693	0.307
S41.1 Open wound of upper arm	0.693	0.307
S42.00 Fracture of clavicle (closed)	0.693	0.307
B48 Other mycoses, not elsewhere classified	0.693	0.307
B47 Mycetoma	0.693	0.307
B46 Zygomycosis	0.693	0.307
B45 Cryptococcosis	0.693	0.307
B43 Chromomycosis and phaeomycotic abscess	0.693	0.307
B42 Sporotrichosis	0.693	0.307
B41 Paracoccidioidomycosis	0.693	0.307
B40 Blastomycosis	0.693	0.307
B39 Histoplasmosis	0.693	0.307
B38 Coccidioidomycosis	0.693	0.307
B36 Other superficial mycoses	0.693	0.307
M25.54 Pain in joint (Hand)	0.692	0.308
V18 Pedal cyclist injured in noncollision transport accident	0.691	0.308
B90-B94 Sequelae of infectious and parasitic diseases	0.691	0.309
J82 Pulmonary eosinophilia, not elsewhere classified	0.691	0.309
H16.0 Corneal ulcer	0.691	0.309
A48 Other bacterial diseases, not elsewhere classified	0.690	0.309
A40 Streptococcal septicaemia	0.690	0.310
Y60-Y69 Misadventures to patients during surgical and medical care	0.690	0.310
B25 Cytomegaloviral disease	0.690	0.310
J30.1 Allergic rhinitis due to pollen	0.689	0.311
M25.56 Pain in joint (Lower leg)	0.689	0.311
T79-T79 Certain early complications of trauma	0.686	0.314
A49.9 Bacterial infection, unspecified	0.685	0.314
H90 Conductive and sensorineural hearing loss	0.685	0.315
J35 Chronic diseases of tonsils and adenoids	0.683	0.317
F30-F39 Mood [affective] disorders	0.683	0.317
I05.9 Mitral valve disease, unspecified	0.681	0.319
E06.3 Autoimmune thyroiditis	0.681	0.319
J96 Respiratory failure, not elsewhere classified	0.679	0.320
I36 Nonrheumatic tricuspid valve disorders	0.679	0.321
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.679	0.321
T85.2 Mechanical complication of intraocular lens	0.679	0.321
T91.9 Sequelae of unspecified injury of neck and trunk	0.678	0.322
E84 Cystic fibrosis	0.678	0.322
E79 Disorders of purine and pyrimidine metabolism	0.678	0.322
E77 Disorders of glycoprotein metabolism	0.678	0.322
E76 Disorders of glycosaminoglycan metabolism	0.678	0.322
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.678	0.322
E74 Other disorders of carbohydrate metabolism	0.678	0.322
E72 Other disorders of amino-acid metabolism	0.678	0.322
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.678	0.322
E70 Disorders of aromatic amino-acid metabolism	0.678	0.322
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.678	0.322
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.678	0.322
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.677	0.322
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.677	0.323
S22 Fracture of rib(s), sternum and thoracic spine	0.677	0.323
Chapter XXII Codes for special purposes	0.676	0.324
J84.1 Other interstitial pulmonary diseases with fibrosis	0.676	0.324
I38 Endocarditis, valve unspecified	0.675	0.324
H93 Other disorders of ear, not elsewhere classified	0.675	0.324
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.675	0.325
S43.0 Dislocation of shoulder joint	0.674	0.326
J90 Pleural effusion, not elsewhere classified	0.674	0.326
I47.0 Reentry ventricular arrhythmia	0.674	0.326
H20 Iridocyclitis	0.673	0.326
Y44 Agents primarily affecting blood constituents	0.673	0.327
S80-S89 Injuries to the knee and lower leg	0.673	0.327
I69.0 Sequelae of subarachnoid haemorrhage	0.673	0.327
J94 Other pleural conditions	0.673	0.327
I99 Other and unspecified disorders of circulatory system	0.672	0.327
I78 Diseases of capillaries	0.672	0.328
I95.2 Hypotension due to drugs	0.672	0.328
H47 Other disorders of optic [2nd] nerve and visual pathways	0.671	0.329
H10-H13 Disorders of conjunctiva	0.670	0.329
J99 Respiratory disorders in diseases classified elsewhere	0.670	0.330
J80 Adult respiratory distress syndrome	0.670	0.330
E73 Lactose intolerance	0.669	0.330
I51.8 Other ill-defined heart diseases	0.669	0.331
I67.2 Cerebral atherosclerosis	0.669	0.331
I51.5 Myocardial degeneration	0.668	0.332
I51.4 Myocarditis, unspecified	0.668	0.332
I51.3 Intracardiac thrombosis, not elsewhere classified	0.668	0.332
I51.2 Rupture of papillary muscle, not elsewhere classified	0.668	0.332
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.668	0.332
I51.0 Cardiac septal defect, acquired	0.668	0.332
F99-F99 Unspecified mental disorder	0.668	0.332
J30.3 Other allergic rhinitis	0.667	0.333
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.666	0.334
I51.9 Heart disease, unspecified	0.666	0.334
V80-V89 Other land transport accidents	0.665	0.334
Y52.1 Calcium-channel blockers	0.666	0.334
S51.9 Open wound of forearm, part unspecified	0.666	0.334
I47.1 Supraventricular tachycardia	0.664	0.336
I61.9 Intracerebral haemorrhage, unspecified	0.664	0.336
E80.4 Gilbert's syndrome	0.663	0.337
J60-J70 Lung diseases due to external agents	0.663	0.337
I69.3 Sequelae of cerebral infarction	0.663	0.337
I30 Acute pericarditis	0.662	0.338
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.662	0.338
T91.1 Sequelae of fracture of spine	0.662	0.338
T86 Failure and rejection of transplanted organs and tissues	0.661	0.338
F60 Specific personality disorders	0.661	0.339
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.661	0.339
S37 Injury of urinary and pelvic organs	0.661	0.339
S36 Injury of intra-abdominal organs	0.661	0.339
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.661	0.339
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.661	0.339
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.661	0.339
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.661	0.339
E46 Unspecified protein-energy malnutrition	0.660	0.340
V48 Car occupant injured in noncollision transport accident	0.660	0.340
T98.1 Sequelae of other and unspecified effects of external causes	0.659	0.341
J38.2 Nodules of vocal cords	0.659	0.341
J95.8 Other postprocedural respiratory disorders	0.659	0.341
W00-W19 Falls	0.658	0.342
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.657	0.343
I27 Other pulmonary heart diseases	0.656	0.344
T91.3 Sequelae of injury of spinal cord	0.656	0.344
S51.0 Open wound of elbow	0.655	0.345
S32.00 Fracture of lumbar vertebra (closed)	0.654	0.346
J10 Influenza due to identified influenza virus	0.654	0.346
Y42.7 Androgens and anabolic congeners	0.654	0.346
A44 Bartonellosis	0.654	0.346
A43 Nocardiosis	0.654	0.346
A42 Actinomycosis	0.654	0.346
A39 Meningococcal infection	0.654	0.346
A37 Whooping cough	0.654	0.346
A36 Diphtheria	0.654	0.346
A32 Listeriosis	0.654	0.346
A31 Infection due to other mycobacteria	0.654	0.346
A30 Leprosy [Hansen's disease]	0.654	0.346
A38 Scarlet fever	0.654	0.346
A35 Other tetanus	0.654	0.346
A34 Obstetrical tetanus	0.654	0.346
A33 Tetanus neonatorum	0.654	0.346
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.653	0.346
X68 Intentional self-poisoning by and exposure to pesticides	0.653	0.347
I05.0 Mitral stenosis	0.650	0.350
I70 Atherosclerosis	0.649	0.351
E29 Testicular dysfunction	0.649	0.351
B37.7 Candidal septicaemia	0.647	0.352
B37.6 Candidal endocarditis	0.647	0.352
B37.5 Candidal meningitis	0.647	0.352
B37.4 Candidiasis of other urogenital sites	0.647	0.352
B37.2 Candidiasis of skin and nail	0.647	0.352
B37.1 Pulmonary candidiasis	0.647	0.352
I71.3 Abdominal aortic aneurysm, ruptured	0.647	0.353
I95.8 Other hypotension	0.647	0.353
I95.0 Idiopathic hypotension	0.647	0.353
T14.0 Superficial injury of unspecified body region	0.647	0.353
S30.1 Contusion of abdominal wall	0.646	0.354
E85.3 Secondary systemic amyloidosis	0.646	0.354
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.646	0.354
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.645	0.355
S12 Fracture of neck	0.645	0.355
D70 Agranulocytosis	0.644	0.356
T15-T19 Effects of foreign body entering through natural orifice	0.643	0.357
S90 Superficial injury of ankle and foot	0.643	0.357
H21 Other disorders of iris and ciliary body	0.643	0.357
Q80-Q89 Other congenital malformations	0.643	0.357
T90.1 Sequelae of open wound of head	0.643	0.357
T92.0 Sequelae of open wound of upper limb	0.642	0.358
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.642	0.358
H53.6 Night blindness	0.642	0.358
H53.5 Colour vision deficiencies	0.642	0.358
H53.3 Other disorders of binocular vision	0.642	0.358
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.642	0.358
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.641	0.359
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.640	0.360
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.640	0.360
J37 Chronic laryngitis and laryngotracheitis	0.640	0.360
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.640	0.360
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.640	0.360
H17 Corneal scars and opacities	0.640	0.360
H15 Disorders of sclera	0.640	0.360
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.640	0.360
J38.0 Paralysis of vocal cords and larynx	0.639	0.361
E03 Other hypothyroidism	0.639	0.361
Y88 Sequelae of surgical and medical care as external cause	0.639	0.361
S42.9 Fracture of shoulder girdle, part unspecified	0.639	0.361
X78 Intentional self-harm by sharp object	0.639	0.361
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.639	0.361
M89 Other disorders of bone	0.638	0.362
J98.8 Other specified respiratory disorders	0.637	0.363
B95-B98 Bacterial, viral and other infectious agents	0.637	0.363
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.637	0.363
Y52.8 Antivaricose drugs, including sclerosing agents	0.637	0.363
Y52.7 Peripheral vasodilators	0.637	0.363
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.637	0.363
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.637	0.363
H25-H28 Disorders of lens	0.637	0.363
T68 Hypothermia	0.636	0.364
Y43.1 Antineoplastic antimetabolites	0.636	0.364
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.636	0.364
B34.9 Viral infection, unspecified	0.635	0.365
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.635	0.365
M60-M63 Disorders of muscles	0.635	0.365
H43-H45 Disorders of vitreous body and globe	0.634	0.366
H53.1 Subjective visual disturbances	0.634	0.366
I08 Multiple valve diseases	0.634	0.366
H18.4 Corneal degeneration	0.633	0.366
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.633	0.367
B15-B19 Viral hepatitis	0.632	0.368
T92.2 Sequelae of fracture at wrist and hand level	0.632	0.368
S51.8 Open wound of other parts of forearm	0.631	0.369
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.631	0.369
A49.0 Staphylococcal infection, unspecified	0.631	0.369
D73 Diseases of spleen	0.631	0.369
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.630	0.370
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.630	0.370
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.630	0.370
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.630	0.370
E65 Localised adiposity	0.630	0.370
S49.9 Unspecified injury of shoulder and upper arm	0.630	0.370
J98.9 Respiratory disorder, unspecified	0.630	0.370
J98.6 Disorders of diaphragm	0.630	0.370
J98.3 Compensatory emphysema	0.630	0.370
J98.2 Interstitial emphysema	0.630	0.370
Y04 Assault by bodily force	0.629	0.371
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.629	0.371
I34.8 Other nonrheumatic mitral valve disorders	0.629	0.371
I34.2 Nonrheumatic mitral (valve) stenosis	0.629	0.371
Y43.9 Primarily systemic agent, unspecified	0.628	0.372
Y43.8 Other primarily systemic agents, not elsewhere classified	0.628	0.372
Y43.6 Enzymes, not elsewhere classified	0.628	0.372
Y43.5 Acidifying and alkalising agents	0.628	0.372
Y43.2 Antineoplastic natural products	0.628	0.372
Y43.0 Antiallergic and antiemetic drugs	0.628	0.372
I09 Other rheumatic heart diseases	0.627	0.373
I06 Rheumatic aortic valve diseases	0.627	0.373
D75.8 Other specified diseases of blood and blood-forming organs	0.626	0.373
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.626	0.374
M91-M94 Chondropathies	0.626	0.374
J38.6 Stenosis of larynx	0.626	0.374
S14 Injury of nerves and spinal cord at neck level	0.625	0.375
D55-D59 Haemolytic anaemias	0.625	0.375
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.625	0.375
D80-D89 Certain disorders involving the immune mechanism	0.624	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations