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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1869717
log Bayes Factor = 14.9172
Chromosome 4   position 140,751,121  (GRCh37) Explore rs1869717 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.992 0.008 0.000
M50-M54 Other dorsopathies
0.991 0.009 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
M54 Dorsalgia
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.981 0.019 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.981 0.019 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
H65-H75 Diseases of middle ear and mastoid
0.979 0.021 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
C78.7 Secondary malignant neoplasm of liver
0.973 0.027 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
M54.5 Low back pain
0.966 0.034 0.000
Z51 Other medical care
0.963 0.037 0.000
H30-H36 Disorders of choroid and retina
0.960 0.040 0.000
B95-B98 Bacterial, viral and other infectious agents
0.960 0.040 0.000
M70-M79 Other soft tissue disorders
0.959 0.041 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.958 0.042 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.958 0.042 0.000
C79 Secondary malignant neoplasm of other sites
0.957 0.043 0.000
F30-F39 Mood [affective] disorders
0.950 0.050 0.000
H90-H95 Other disorders of ear
0.950 0.050 0.000
C15-C26 Malignant neoplasms of digestive organs
0.950 0.050 0.000
E10 Insulin-dependent diabetes mellitus
0.943 0.057 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.941 0.059 0.000
R26 Abnormalities of gait and mobility
0.936 0.064 0.000
C64-C68 Malignant neoplasms of urinary tract
0.934 0.066 0.000
R29.6 Tendency to fall, not elsewhere classified
0.933 0.067 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.926 0.074 0.000
F32 Depressive episode
0.924 0.076 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.919 0.081 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.918 0.082 0.000
E00-E07 Disorders of thyroid gland
0.918 0.082 0.000
H72 Perforation of tympanic membrane
0.916 0.084 0.000
H33 Retinal detachments and breaks
0.915 0.085 0.000
Z46 Fitting and adjustment of other devices
0.914 0.086 0.000
Z43 Attention to artificial openings
0.912 0.088 0.000
S01 Open wound of head
0.911 0.089 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.909 0.091 0.000
M54.57 Low back pain (Lumbosacral region)
0.908 0.092 0.000
M86-M90 Other osteopathies
0.907 0.093 0.000
C18 Malignant neoplasm of colon
0.906 0.094 0.000
H65 Nonsuppurative otitis media
0.900 0.100 0.000
C51-C58 Malignant neoplasms of female genital organs
0.897 0.103 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.893 0.107 0.000
M54.56 Low back pain (Lumbar region)
0.891 0.109 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.890 0.110 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.889 0.111 0.000
Z51.5 Palliative care
0.888 0.112 0.000
H35 Other retinal disorders
0.884 0.116 0.000
Chapter XX External causes of morbidity and mortality
0.883 0.117 0.000
S00 Superficial injury of head
0.883 0.117 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.880 0.120 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.880 0.120 0.000
E11 Non-insulin-dependent diabetes mellitus
0.878 0.122 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.878 0.122 0.000
T66-T78 Other and unspecified effects of external causes
0.877 0.123 0.000
F32.9 Depressive episode, unspecified
0.873 0.127 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.873 0.127 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.871 0.129 0.000
M79.0 Rheumatism, unspecified
0.869 0.131 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.869 0.131 0.000
S06 Intracranial injury
0.869 0.131 0.000
C80 Malignant neoplasm without specification of site
0.865 0.135 0.000
B15-B19 Viral hepatitis
0.861 0.139 0.000
C18.7 Sigmoid colon
0.860 0.140 0.000
M54.4 Lumbago with sciatica
0.857 0.143 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.857 0.143 0.000
Z51.3 Blood transfusion without reported diagnosis
0.856 0.144 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.853 0.147 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.850 0.150 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.850 0.150 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.848 0.152 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
E10.4 With neurological complications
0.843 0.157 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.843 0.157 0.000
A30-A49 Other bacterial diseases
0.842 0.158 0.000
H33.2 Serous retinal detachment
0.842 0.158 0.000
H93 Other disorders of ear, not elsewhere classified
0.841 0.159 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.840 0.160 0.000
C56 Malignant neoplasm of ovary
0.838 0.162 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.836 0.164 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.836 0.164 0.000
Z33 Pregnant state, incidental
0.835 0.165 0.000
H55-H59 Other disorders of eye and adnexa
0.834 0.166 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.833 0.167 0.000
C67 Malignant neoplasm of bladder
0.832 0.168 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.832 0.168 0.000
Z51.8 Other specified medical care
0.832 0.168 0.000
H71 Cholesteatoma of middle ear
0.828 0.172 0.000
H90 Conductive and sensorineural hearing loss
0.827 0.173 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.825 0.175 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.178 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.821 0.179 0.000
G70-G73 Diseases of myoneural junction and muscle
0.817 0.183 0.000
Z35 Supervision of high-risk pregnancy
0.817 0.183 0.000
M75 Shoulder lesions
0.815 0.185 0.000
E50-E64 Other nutritional deficiencies
0.815 0.185 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.815 0.185 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.813 0.187 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.813 0.187 0.000
M89 Other disorders of bone
0.813 0.187 0.000
S10-S19 Injuries to the neck
0.811 0.189 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.810 0.190 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.810 0.190 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.810 0.190 0.000
H65.3 Chronic mucoid otitis media
0.809 0.191 0.000
M40-M43 Deforming dorsopathies
0.808 0.192 0.000
E40-E46 Malnutrition
0.807 0.193 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.806 0.194 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.803 0.197 0.000
B35-B49 Mycoses
0.803 0.197 0.000
E10.5 With peripheral circulatory complications
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.795 0.205 0.000
Z41 Procedures for purposes other than remedying health state
0.795 0.205 0.000
R47-R49 Symptoms and signs involving speech and voice
0.792 0.208 0.000
Z51.1 Chemotherapy session for neoplasm
0.792 0.208 0.000
M50 Cervical disk disorders
0.792 0.208 0.000
T78 Adverse effects, not elsewhere classified
0.791 0.209 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.790 0.210 0.000
H10-H13 Disorders of conjunctiva
0.790 0.210 0.000
H69 Other disorders of Eustachian tube
0.788 0.212 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.788 0.212 0.000
W00-W19 Falls
0.788 0.212 0.000
Chapter XI Diseases of the digestive system
0.788 0.212 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.786 0.214 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.785 0.215 0.000
T79-T79 Certain early complications of trauma
0.785 0.215 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.784 0.216 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.219 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.781 0.219 0.000
M53 Other dorsopathies, not elsewhere classified
0.779 0.221 0.000
E70-E90 Metabolic disorders
0.779 0.221 0.000
E10.9 Without complications
0.777 0.223 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.777 0.223 0.000
Z54 Convalescence
0.776 0.224 0.000
H36 Retinal disorders in diseases classified elsewhere
0.776 0.224 0.000
H33.3 Retinal breaks without detachment
0.775 0.225 0.000
E04 Other non-toxic goitre
0.774 0.226 0.000
S01.9 Open wound of head, part unspecified
0.772 0.228 0.000
Z51.9 Medical care, unspecified
0.772 0.228 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.772 0.228 0.000
B18 Chronic viral hepatitis
0.772 0.228 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.770 0.230 0.000
C18.2 Ascending colon
0.770 0.230 0.000
E11.9 Without complications
0.770 0.230 0.000
M45-M49 Spondylopathies
0.768 0.231 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.768 0.232 0.000
M54.9 Dorsalgia, unspecified
0.766 0.234 0.000
H74 Other disorders of middle ear and mastoid
0.765 0.235 0.000
H93.1 Tinnitus
0.764 0.236 0.000
E06 Thyroiditis
0.763 0.237 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.763 0.237 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.762 0.238 0.000
Z39 Postpartum care and examination
0.761 0.239 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.761 0.239 0.000
L20-L30 Dermatitis and eczema
0.761 0.239 0.000
Y40 Systemic antibiotics
0.760 0.240 0.000
S00.9 Superficial injury of head, part unspecified
0.759 0.241 0.000
G90-G99 Other disorders of the nervous system
0.758 0.242 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.757 0.243 0.000
K65-K67 Diseases of peritoneum
0.757 0.243 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.756 0.244 0.000
M54.1 Radiculopathy
0.756 0.244 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.755 0.245 0.000
S40-S49 Injuries to the shoulder and upper arm
0.754 0.246 0.000
F30 Manic episode
0.754 0.246 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.752 0.248 0.000
H35.7 Separation of retinal layers
0.750 0.249 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.750 0.250 0.000
S00.1 Contusion of eyelid and periocular area
0.748 0.252 0.000
S01.0 Open wound of scalp
0.748 0.252 0.000
Z43.8 Attention to other artificial openings
0.745 0.254 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
M89.9 Disorder of bone, unspecified
0.745 0.255 0.000
S01.4 Open wound of cheek and temporomandibular area
0.745 0.255 0.000
G30-G32 Other degenerative diseases of the nervous system
0.744 0.256 0.000
M67 Other disorders of synovium and tendon
0.744 0.256 0.000
M79.7 Fibromyalgia
0.744 0.256 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.744 0.256 0.000
E10.2 With renal complications
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.743 0.257 0.000
S00.0 Superficial injury of scalp
0.741 0.259 0.000
Z46.8 Fitting and adjustment of other specified devices
0.740 0.260 0.000
M75.0 Adhesive capsulitis of shoulder
0.739 0.261 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.738 0.262 0.000
G47 Sleep disorders
0.738 0.262 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.736 0.264 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.734 0.266 0.000
E05.9 Thyrotoxicosis, unspecified
0.733 0.267 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.733 0.267 0.000
C18.3 Hepatic flexure
0.733 0.267 0.000
H35.0 Background retinopathy and retinal vascular changes
0.732 0.268 0.000
M91-M94 Chondropathies
0.732 0.268 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.730 0.270 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.730 0.270 0.000
H33.5 Other retinal detachments
0.730 0.270 0.000
Z43.1 Attention to gastrostomy
0.729 0.271 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.729 0.271 0.000
F80-F89 Disorders of psychological development
0.729 0.271 0.000
C65 Malignant neoplasm of renal pelvis
0.728 0.272 0.000
E11.4 With neurological complications
0.728 0.272 0.000
F31 Bipolar affective disorder
0.726 0.273 0.000
R26.3 Immobility
0.726 0.274 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.726 0.274 0.000
E14 Unspecified diabetes mellitus
0.726 0.274 0.000
S01.7 Multiple open wounds of head
0.726 0.274 0.000
C21 Malignant neoplasm of anus and anal canal
0.724 0.276 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.723 0.277 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.723 0.277 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.722 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.278 0.000
M79.1 Myalgia
0.721 0.279 0.000
H34 Retinal vascular occlusions
0.721 0.279 0.000
K70-K77 Diseases of liver
0.721 0.279 0.000
F20 Schizophrenia
0.721 0.279 0.000
Z03.8 Observation for other suspected diseases and conditions
0.720 0.280 0.000
M54.6 Pain in thoracic spine
0.720 0.280 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
M20-M25 Other joint disorders
0.719 0.281 0.000
A49 Bacterial infection of unspecified site
0.719 0.281 0.000
F32.0 Mild depressive episode
0.717 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
S20-S29 Injuries to the thorax
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
H91 Other hearing loss
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.716 0.284 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
E78.5 Hyperlipidaemia, unspecified
0.715 0.285 0.000
Z49 Care involving dialysis
0.715 0.285 0.000
R25 Abnormal involuntary movements
0.715 0.285 0.000
H20 Iridocyclitis
0.715 0.285 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
L40-L45 Papulosquamous disorders
0.713 0.287 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.713 0.287 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.711 0.289 0.000
G62 Other polyneuropathies
0.711 0.289 0.000
Z31 Procreative management
0.711 0.289 0.000
G47.3 Sleep apnoea
0.710 0.290 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
Z03.1 Observation for suspected malignant neoplasm
0.710 0.290 0.000
A40 Streptococcal septicaemia
0.709 0.291 0.000
M47 Spondylosis
0.709 0.291 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.708 0.292 0.000
M87 Osteonecrosis
0.708 0.292 0.000
M79.8 Other specified soft tissue disorders
0.708 0.292 0.000
B18.2 Chronic viral hepatitis C
0.708 0.292 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
C71 Malignant neoplasm of brain
0.706 0.294 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.705 0.295 0.000
Y52 Agents primarily affecting the cardiovascular system
0.705 0.295 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.704 0.296 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.704 0.296 0.000
S06.4 Epidural haemorrhage
0.704 0.296 0.000
Z52 Donors of organs and tissues
0.703 0.297 0.000
Z44 Fitting and adjustment of external prosthetic device
0.703 0.297 0.000
E04.1 Non-toxic single thyroid nodule
0.702 0.298 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.702 0.298 0.000
E13 Other specified diabetes mellitus
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.702 0.298 0.000
H70 Mastoiditis and related conditions
0.702 0.298 0.000
H68 Eustachian salpingitis and obstruction
0.702 0.298 0.000
H67 Otitis media in diseases classified elsewhere
0.702 0.298 0.000
H65.4 Other chronic nonsuppurative otitis media
0.701 0.299 0.000
S06.2 Diffuse brain injury
0.701 0.299 0.000
S01.1 Open wound of eyelid and periocular area
0.701 0.299 0.000
E65-E68 Obesity and other hyperalimentation
0.701 0.299 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.700 0.300 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.700 0.300 0.000
C66 Malignant neoplasm of ureter
0.700 0.300 0.000
R21 Rash and other nonspecific skin eruption
0.700 0.300 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.300 0.000
F70-F79 Mental retardation
0.699 0.300 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.699 0.301 0.000
S01.2 Open wound of nose
0.699 0.301 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.699 0.301 0.000
C50-C50 Malignant neoplasm of breast
0.698 0.302 0.000
Z29 Need for other prophylactic measures
0.698 0.302 0.000
H35.3 Degeneration of macula and posterior pole
0.698 0.302 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.697 0.303 0.000
C01 Malignant neoplasm of base of tongue
0.696 0.304 0.000
M54.3 Sciatica
0.696 0.304 0.000
S09 Other and unspecified injuries of head
0.696 0.304 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.695 0.305 0.000
G61 Inflammatory polyneuropathy
0.695 0.305 0.000
C18.5 Splenic flexure
0.694 0.305 0.000
H35.4 Peripheral retinal degeneration
0.694 0.306 0.000
F60-F69 Disorders of adult personality and behaviour
0.694 0.306 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.693 0.307 0.000
H16 Keratitis
0.693 0.307 0.000
M54.55 Low back pain (Thoracolumbar region)
0.692 0.307 0.000
M54.54 Low back pain-Thoracic
0.692 0.307 0.000
M54.53 Low back pain-Cervicothoracic
0.692 0.307 0.000
M54.52 Low back pain-Cervical
0.692 0.307 0.000
M54.51 Low back pain-Occipit-atl-axl
0.692 0.307 0.000
M54.50 Low back pain (Multiple sites in spine)
0.692 0.307 0.000
Z32 Pregnancy examination and test
0.692 0.308 0.000
Z03.3 Observation for suspected nervous system disorder
0.692 0.308 0.000
M54.59 Low back pain (Site unspecified)
0.692 0.308 0.000
M77 Other enthesopathies
0.692 0.308 0.000
S02 Fracture of skull and facial bones
0.691 0.308 0.000
K66 Other disorders of peritoneum
0.691 0.309 0.000
Z51.6 Desensitisation to allergens
0.690 0.309 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.310 0.000
C16 Malignant neoplasm of stomach
0.689 0.311 0.000
E07 Other disorders of thyroid
0.689 0.311 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.689 0.311 0.000
H31 Other disorders of choroid
0.689 0.311 0.000
H30 Chorioretinal inflammation
0.689 0.311 0.000
M76 Enthesopathies of lower limb, excluding foot
0.688 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.688 0.312 0.000
C18.1 Appendix
0.688 0.312 0.000
G63.2 Diabetic polyneuropathy
0.687 0.313 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.687 0.313 0.000
C79.6 Secondary malignant neoplasm of ovary
0.687 0.313 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.686 0.314 0.000
S19 Other and unspecified injuries of neck
0.685 0.315 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.685 0.315 0.000
B25-B34 Other viral diseases
0.684 0.316 0.000
C18.0 Caecum
0.684 0.316 0.000
K65 Peritonitis
0.683 0.317 0.000
Y40.8 Other systemic antibiotics
0.683 0.317 0.000
S06.5 Traumatic subdural haemorrhage
0.682 0.318 0.000
H35.9 Retinal disorder, unspecified
0.682 0.318 0.000
C67.6 Ureteric orifice
0.681 0.319 0.000
H21 Other disorders of iris and ciliary body
0.681 0.319 0.000
F38 Other mood [affective] disorders
0.681 0.319 0.000
F34 Persistent mood [affective] disorders
0.681 0.319 0.000
F39 Unspecified mood [affective] disorder
0.681 0.319 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.681 0.319 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.681 0.319 0.000
C17 Malignant neoplasm of small intestine
0.681 0.319 0.000
C23 Malignant neoplasm of gallbladder
0.681 0.319 0.000
H55 Nystagmus and other irregular eye movements
0.680 0.320 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.680 0.320 0.000
H90.2 Conductive hearing loss, unspecified
0.679 0.321 0.000
M88 Paget's disease of bone [osteitis deformans]
0.679 0.321 0.000
C67.1 Dome of bladder
0.679 0.321 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.677 0.323 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.677 0.323 0.000
E10.8 With unspecified complications
0.676 0.324 0.000
E10.7 With multiple complications
0.676 0.324 0.000
E10.6 With other specified complications
0.676 0.324 0.000
E10.0 With coma
0.676 0.324 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.676 0.324 0.000
E55 Vitamin D deficiency
0.675 0.325 0.000
R27 Other lack of coordination
0.674 0.325 0.000
R29.4 Clicking hip
0.674 0.326 0.000
R29.3 Abnormal posture
0.674 0.326 0.000
R29.2 Abnormal reflex
0.674 0.326 0.000
R29.1 Meningismus
0.674 0.326 0.000
R29.0 Tetany
0.674 0.326 0.000
M71 Other bursopathies
0.673 0.327 0.000
M54.2 Cervicalgia
0.673 0.327 0.000
E10.3 With ophthalmic complications
0.672 0.328 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.672 0.328 0.000
E46 Unspecified protein-energy malnutrition
0.672 0.328 0.000
R26.1 Paralytic gait
0.671 0.329 0.000
R26.0 Ataxic gait
0.671 0.329 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.671 0.329 0.000
R49 Voice disturbances
0.670 0.330 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.670 0.330 0.000
K35-K38 Diseases of appendix
0.669 0.331 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.668 0.332 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.667 0.332 0.000
H95.1 Other disorders following mastoidectomy
0.667 0.332 0.000
S06.8 Other intracranial injuries
0.667 0.333 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.667 0.333 0.000
F32.1 Moderate depressive episode
0.666 0.334 0.000
S00.7 Multiple superficial injuries of head
0.665 0.335 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.665 0.335 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.664 0.336 0.000
E10.1 With ketoacidosis
0.664 0.336 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.663 0.337 0.000
F32.8 Other depressive episodes
0.663 0.337 0.000
C67.2 Lateral wall of bladder
0.662 0.338 0.000
C69 Malignant neoplasm of eye and adnexa
0.662 0.338 0.000
Y42.5 Other oestrogens and progestogens
0.662 0.338 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.661 0.339 0.000
L82 Seborrhoeic keratosis
0.661 0.339 0.000
H11 Other disorders of conjunctiva
0.660 0.339 0.000
K13 Other diseases of lip and oral mucosa
0.660 0.340 0.000
C51 Malignant neoplasm of vulva
0.659 0.341 0.000
M79.9 Soft tissue disorder, unspecified
0.659 0.341 0.000
M79.5 Residual foreign body in soft tissue
0.659 0.341 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.659 0.341 0.000
M79.3 Panniculitis, unspecified
0.659 0.341 0.000
M79.2 Neuralgia and neuritis, unspecified
0.659 0.341 0.000
C15 Malignant neoplasm of oesophagus
0.659 0.341 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.658 0.342 0.000
E00 Congenital iodine-deficiency syndrome
0.658 0.342 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.658 0.342 0.000
M24 Other specific joint derangements
0.658 0.342 0.000
Z35.8 Supervision of other high-risk pregnancies
0.657 0.343 0.000
G71 Primary disorders of muscles
0.657 0.343 0.000
C67.5 Bladder neck
0.657 0.343 0.000
R20 Disturbances of skin sensation
0.657 0.343 0.000
H72.8 Other perforations of tympanic membrane
0.656 0.343 0.000
H72.2 Other marginal perforations of tympanic membrane
0.656 0.343 0.000
H72.1 Attic perforation of tympanic membrane
0.656 0.343 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.656 0.344 0.000
H33.4 Traction detachment of retina
0.656 0.344 0.000
H33.1 Retinoschisis and retinal cysts
0.656 0.344 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.656 0.344 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.655 0.344 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.655 0.344 0.000
Z46.1 Fitting and adjustment of hearing aid
0.655 0.344 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.655 0.344 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.655 0.345 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
T78.4 Allergy, unspecified
0.654 0.346 0.000
Z43.9 Attention to unspecified artificial opening
0.654 0.346 0.000
Z43.7 Attention to artificial vagina
0.654 0.346 0.000
Z43.5 Attention to cyctostomy
0.654 0.346 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.654 0.346 0.000
Z43.0 Attention to tracheostomy
0.654 0.346 0.000
C78.0 Secondary malignant neoplasm of lung
0.653 0.347 0.000
W18 Other fall on same level
0.653 0.347 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.652 0.348 0.000
H69.9 Eustachian tube disorder, unspecified
0.652 0.348 0.000
Z38 Liveborn infants according to place of birth
0.651 0.348 0.000
R81 Glycosuria
0.651 0.349 0.000
K12 Stomatitis and related lesions
0.651 0.349 0.000
L85 Other epidermal thickening
0.651 0.349 0.000
C77.3 Axillary and upper limb lymph nodes
0.651 0.349 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.650 0.350 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.650 0.350 0.000
M90 Osteopathies in diseases classified elsewhere
0.650 0.350 0.000
C18.8 Overlapping lesion of colon
0.649 0.351 0.000
Z39.1 Care and examination of lactating mother
0.649 0.351 0.000
K76 Other diseases of liver
0.649 0.351 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.649 0.351 0.000
Z51.0 Radiotherapy session
0.649 0.351 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.649 0.351 0.000
S01.3 Open wound of ear
0.648 0.352 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.648 0.352 0.000
H43-H45 Disorders of vitreous body and globe
0.647 0.353 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.647 0.353 0.000
G72 Other myopathies
0.646 0.353 0.000
T68 Hypothermia
0.646 0.354 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.646 0.354 0.000
M72 Fibroblastic disorders
0.646 0.354 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.646 0.354 0.000
C67.4 Posterior wall of bladder
0.645 0.354 0.000
C77.9 Lymph node, unspecified
0.645 0.354 0.000
H65.2 Chronic serous otitis media
0.645 0.355 0.000
H65.1 Other acute nonsuppurative otitis media
0.645 0.355 0.000
H65.0 Acute serous otitis media
0.645 0.355 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.645 0.355 0.000
T78.3 Angioneurotic oedema
0.645 0.355 0.000
B37 Candidiasis
0.645 0.355 0.000
M41 Scoliosis
0.645 0.355 0.000
M67.8 Other specified disorders of synovium and tendon
0.645 0.355 0.000
M40 Kyphosis and lordosis
0.645 0.355 0.000
H36.0 Diabetic retinopathy
0.644 0.356 0.000
M86 Osteomyelitis
0.643 0.357 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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