TreeWAS – Variant ID: rs1872085

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.048	0.952	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.028	0.972	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.027	0.973	0.000
S83.2 Tear of meniscus, current	0.027	0.973	0.000
S83.3 Tear of articular cartilage of knee, current	0.024	0.975	0.000
M72.2 Plantar fascial fibromatosis	0.023	0.977	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.022	0.978	0.000
S83.7 Injury to multiple structures of knee	0.021	0.979	0.000
S83.1 Dislocation of knee	0.020	0.980	0.000
S83.0 Dislocation of patella	0.020	0.980	0.000
D47.2 Monoclonal gammopathy	0.000	0.980	0.019
S89.9 Unspecified injury of lower leg	0.019	0.981	0.000
M72.28 Plantar fascial fibromatosis-Other	0.016	0.983	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.016	0.983	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.016	0.983	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.016	0.983	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.016	0.983	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.016	0.983	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.016	0.983	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.016	0.983	0.000
E10.1 With ketoacidosis	0.000	0.983	0.017
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.016	0.984	0.000
H81.1 Benign paroxysmal vertigo	0.016	0.984	0.000
M72.29 Plantar fascial fibromatosis-Site unspec	0.016	0.984	0.000
H81 Disorders of vestibular function	0.012	0.988	0.000
S89 Other and unspecified injuries of lower leg	0.011	0.989	0.000
H81.2 Vestibular neuronitis	0.011	0.989	0.000
H81.9 Disorder of vestibular function, unspecified	0.011	0.989	0.000
H81.3 Other peripheral vertigo	0.009	0.991	0.000
H81.8 Other disorders of vestibular function	0.009	0.991	0.000
E28.2 Polycystic ovarian syndrome	0.009	0.991	0.000
R49.0 Dysphonia	0.009	0.991	0.000
H81.4 Vertigo of central origin	0.009	0.991	0.000
S80-S89 Injuries to the knee and lower leg	0.009	0.991	0.000
S89.7 Multiple injuries of lower leg	0.008	0.992	0.000
S89.1 Other specified injuries of lower leg	0.008	0.992	0.000
S89.0 Multiple injuries of lower leg	0.008	0.992	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.993	0.007
S87 Crushing injury of lower leg	0.007	0.993	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.993	0.007
E10.8 With unspecified complications	0.000	0.993	0.007
E10.5 With peripheral circulatory complications	0.000	0.993	0.007
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.993	0.007
S84 Injury of nerves at lower leg level	0.007	0.993	0.000
E28 Ovarian dysfunction	0.007	0.993	0.000
M72 Fibroblastic disorders	0.007	0.993	0.000
S88 Traumatic amputation of lower leg	0.006	0.994	0.000
S85 Injury of blood vessels at lower leg level	0.006	0.994	0.000
E10.0 With coma	0.000	0.994	0.006
M95.0 Acquired deformity of nose	0.006	0.994	0.000
H81.0 Meniere's disease	0.006	0.994	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.006	0.994	0.000
E28.3 Primary ovarian failure	0.006	0.994	0.000
E83.5 Disorders of calcium metabolism	0.000	0.994	0.006
E10.2 With renal complications	0.000	0.994	0.006
D47.4 Osteomyelofibrosis	0.000	0.994	0.006
S89.8 Other specified injuries of lower leg	0.005	0.994	0.000
M72.9 Fibroblastic disorder, unspecified	0.006	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.005	0.995	0.000
S87.0 Crushing injury of knee	0.005	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.005	0.995	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.995	0.005
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.995	0.005
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.995	0.005
S84.9 Injury of unspecified nerve at lower leg level	0.005	0.995	0.000
S84.8 Injury of other nerves at lower leg level	0.005	0.995	0.000
S84.7 Injury of multiple nerves at lower leg level	0.005	0.995	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.005	0.995	0.000
S84.0 Injury of tibial nerve at lower leg level	0.005	0.995	0.000
M72.94 Fibroblastic disorder, unspecified (Hand)	0.005	0.995	0.000
E28.9 Ovarian dysfunction, unspecified	0.005	0.995	0.000
E28.8 Other ovarian dysfunction	0.005	0.995	0.000
E28.1 Androgen excess	0.005	0.995	0.000
E28.0 Oestrogen excess	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.005	0.995	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.995	0.005
M72.8 Other fibroblastic disorders	0.005	0.995	0.000
M72.6 Necrotizing fasciitis	0.005	0.995	0.000
M72.4 Pseudosarcomatous fibromatosis	0.005	0.995	0.000
M72.3 Nodular fasciitis	0.005	0.995	0.000
S52.80 Fracture of other parts of forearm (closed)	0.005	0.995	0.000
E10.7 With multiple complications	0.000	0.995	0.005
S85.9 Injury of unspecified blood vessel at lower leg level	0.005	0.995	0.000
S85.8 Injury of other blood vessels at lower leg level	0.005	0.995	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.005	0.995	0.000
S85.5 Injury of popliteal vein	0.005	0.995	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.005	0.995	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.005	0.995	0.000
S85.2 Injury of peroneal artery	0.005	0.995	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.005	0.995	0.000
S85.0 Injury of popliteal artery	0.005	0.995	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.005	0.995	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.005	0.995	0.000
S88.0 Traumatic amputation at knee level	0.005	0.995	0.000
M72.5 Fasciitis, not elsewhere classified	0.005	0.995	0.000
S42.00 Fracture of clavicle (closed)	0.005	0.995	0.000
E10.6 With other specified complications	0.000	0.995	0.004
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
C25.2 Tail of pancreas	0.005	0.995	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.996	0.004
M72.1 Knuckle pads	0.004	0.996	0.000
B07 Viral warts	0.004	0.996	0.000
E27.2 Addisonian crisis	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.996	0.000
M72.99 Fibroblastic disorder, unspecified (Site unspecified)	0.004	0.996	0.000
M72.98 Fibroblastic disorder, unspecified (Other)	0.004	0.996	0.000
M72.97 Fibroblastic disorder, unspecified (Ankle and foot)	0.004	0.996	0.000
M72.96 Fibroblastic disorder, unspecified (Lower leg)	0.004	0.996	0.000
M72.95 Fibroblastic disorder, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M72.93 Fibroblastic disorder, unspecified (Forearm)	0.004	0.996	0.000
M72.92 Fibroblastic disorder, unspecified (Upper arm)	0.004	0.996	0.000
M72.91 Fibroblastic disorder, unspecified (Shoulder region)	0.004	0.996	0.000
M72.90 Fibroblastic disorder, unspecified (Multiple sites)	0.004	0.996	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.996	0.004
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.004	0.996	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
S86.0 Injury of Achilles tendon	0.004	0.996	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.004	0.996	0.000
K86.1 Other chronic pancreatitis	0.000	0.996	0.004
E27.5 Adrenomedullary hyperfunction	0.004	0.996	0.000
E27.0 Other adrenocortical overactivity	0.004	0.996	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.996	0.004
M72.39 Nodular fasciitis-Site unspec	0.004	0.996	0.000
M72.38 Nodular fasciitis-Other	0.004	0.996	0.000
M72.37 Nodular fasciitis-Ankle/Foot	0.004	0.996	0.000
M72.36 Nodular fasciitis-Lower Leg	0.004	0.996	0.000
M72.35 Nodular fasciitis-Pelvic/Thigh	0.004	0.996	0.000
M72.34 Nodular fasciitis-Hand	0.004	0.996	0.000
M72.33 Nodular fasciitis-Forearm	0.004	0.996	0.000
M72.32 Nodular fasciitis-Upper arm	0.004	0.996	0.000
M72.31 Nodular fasciitis-Shldr region	0.004	0.996	0.000
M72.30 Nodular fasciitis-Mult sites	0.004	0.996	0.000
M72.49 Pseudosarcomatous fibromatosis (Site unspecified)	0.004	0.996	0.000
M72.48 Pseudosarcomatous fibromatosis (Other)	0.004	0.996	0.000
M72.47 Pseudosarcomatous fibromatosis (Ankle and foot)	0.004	0.996	0.000
M72.46 Pseudosarcomatous fibromatosis (Lower leg)	0.004	0.996	0.000
M72.45 Pseudosarcomatous fibromatosis (Pelvic region and thigh)	0.004	0.996	0.000
M72.44 Pseudosarcomatous fibromatosis (Hand)	0.004	0.996	0.000
M72.43 Pseudosarcomatous fibromatosis (Forearm)	0.004	0.996	0.000
M72.42 Pseudosarcomatous fibromatosis (Upper arm)	0.004	0.996	0.000
M72.41 Pseudosarcomatous fibromatosis (Shoulder region)	0.004	0.996	0.000
M72.40 Pseudosarcomatous fibromatosis (Multiple sites)	0.004	0.996	0.000
M72.69 Necrotizing fasciitis (Site unspecified)	0.004	0.996	0.000
M72.68 Necrotizing fasciitis (Other)	0.004	0.996	0.000
M72.67 Necrotizing fasciitis (Ankle and foot)	0.004	0.996	0.000
M72.66 Necrotizing fasciitis (Lower leg)	0.004	0.996	0.000
M72.65 Necrotizing fasciitis (Pelvic region and thigh)	0.004	0.996	0.000
M72.64 Necrotizing fasciitis (Hand)	0.004	0.996	0.000
M72.63 Necrotizing fasciitis (Forearm)	0.004	0.996	0.000
M72.62 Necrotizing fasciitis (Upper arm)	0.004	0.996	0.000
M72.61 Necrotizing fasciitis (Shoulder region)	0.004	0.996	0.000
M72.60 Necrotizing fasciitis (Multiple sites)	0.004	0.996	0.000
M72.89 Other fibroblastic disorders (Site unspecified)	0.004	0.996	0.000
M72.88 Other fibroblastic disorders (Other)	0.004	0.996	0.000
M72.87 Other fibroblastic disorders (Ankle and foot)	0.004	0.996	0.000
M72.86 Other fibroblastic disorders (Lower leg)	0.004	0.996	0.000
M72.85 Other fibroblastic disorders (Pelvic region and thigh)	0.004	0.996	0.000
M72.84 Other fibroblastic disorders (Hand)	0.004	0.996	0.000
M72.83 Other fibroblastic disorders (Forearm)	0.004	0.996	0.000
M72.82 Other fibroblastic disorders (Upper arm)	0.004	0.996	0.000
M72.81 Other fibroblastic disorders (Shoulder region)	0.004	0.996	0.000
M72.80 Other fibroblastic disorders (Multiple sites)	0.004	0.996	0.000
C21.0 Anus, unspecified	0.004	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.004	0.996	0.000
E10.4 With neurological complications	0.000	0.996	0.004
M72.59 Fasciitis, not elsewhere classified-Site unspec	0.003	0.996	0.000
M72.57 Fasciitis, not elsewhere classified-Ankle/Foot	0.003	0.996	0.000
M72.56 Fasciitis, not elsewhere classified-Lower Leg	0.003	0.996	0.000
M72.55 Fasciitis, not elsewhere classified-Pelvic/Thigh	0.003	0.996	0.000
M72.54 Fasciitis, not elsewhere classified-Hand	0.003	0.996	0.000
M72.53 Fasciitis, not elsewhere classified-Forearm	0.003	0.996	0.000
M72.52 Fasciitis, not elsewhere classified-Upper arm	0.003	0.996	0.000
M72.51 Fasciitis, not elsewhere classified-Shldr region	0.003	0.996	0.000
M72.50 Fasciitis, not elsewhere classified-Mult sites	0.003	0.996	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.003	0.996	0.000
B37.0 Candidal stomatitis	0.000	0.996	0.004
L85.8 Other specified epidermal thickening	0.000	0.996	0.004
K61.3 Ischiorectal abscess	0.004	0.996	0.000
C25.3 Pancreatic duct	0.004	0.996	0.000
M72.58 Fasciitis, not elsewhere classified-Other	0.003	0.996	0.000
C25.7 Other parts of pancreas	0.003	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.996	0.000
M72.19 Knuckle pads (Site unspecified)	0.003	0.997	0.000
M72.18 Knuckle pads-Other	0.003	0.997	0.000
M72.17 Knuckle pads (Ankle and foot)	0.003	0.997	0.000
M72.16 Knuckle pads-Lower Leg	0.003	0.997	0.000
M72.15 Knuckle pads-Pelvic/Thigh	0.003	0.997	0.000
M72.13 Knuckle pads-Forearm	0.003	0.997	0.000
M72.12 Knuckle pads-Upper arm	0.003	0.997	0.000
M72.11 Knuckle pads-Shldr region	0.003	0.997	0.000
M72.10 Knuckle pads (Multiple sites)	0.003	0.997	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
R49 Voice disturbances	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
S71.1 Open wound of thigh	0.000	0.997	0.003
C25.4 Endocrine pancreas	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.997	0.003
S86.00 Unspecified injury of Achilles tendon	0.003	0.997	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.997	0.003
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.003	0.997	0.000
M48.0 Spinal stenosis	0.000	0.997	0.003
M95.4 Acquired deformity of chest and rib	0.003	0.997	0.000
C25.1 Body of pancreas	0.003	0.997	0.000
M72.14 Knuckle pads (Hand)	0.003	0.997	0.000
M95.3 Acquired deformity of neck	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
N34.2 Other urethritis	0.000	0.997	0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.003	0.997	0.000
M95.1 Cauliflower ear	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.003	0.997	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.003	0.997	0.000
M95.5 Acquired deformity of pelvis	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
R49.2 Hypernasality and hyponasality	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
R49.1 Aphonia	0.002	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
E20 Hypoparathyroidism	0.002	0.997	0.000
E32.8 Other diseases of thymus	0.002	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.997	0.000
N34.3 Urethral syndrome, unspecified	0.000	0.998	0.002
E24 Cushing's syndrome	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.001
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.002	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.998	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.002
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.998	0.002
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
C18.9 Colon, unspecified	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
D04.2 Skin of ear and external auricular canal	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
S71.0 Open wound of hip	0.000	0.998	0.002
E29 Testicular dysfunction	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.002
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
N34 Urethritis and urethral syndrome	0.000	0.998	0.002
S71 Open wound of hip and thigh	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
K63.9 Disease of intestine, unspecified	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
K86 Other diseases of pancreas	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.000	0.998	0.002
S52.81 Fracture of other parts of forearm (open)	0.002	0.998	0.000
R25.2 Cramp and spasm	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
T59.8 Other specified gases, fumes and vapours	0.000	0.998	0.002
H92.0 Otalgia	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
K63.2 Fistula of intestine	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
N82.3 Fistula of vagina to large intestine	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.001	0.998	0.001
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.002
C21.1 Anal canal	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
M99.83 Other biomechanical lesions (Lumbar region)	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.998	0.002
S82.2 Fracture of shaft of tibia	0.001	0.998	0.001
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.001	0.998	0.000
E34.4 Constitutional tall stature	0.001	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.001
D04.8 Skin of other sites	0.000	0.998	0.002
D04.0 Skin of lip	0.000	0.998	0.002
D06.9 Cervix, unspecified	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
N19 Unspecified renal failure	0.002	0.998	0.000
Z91.6 Personal history of other physical trauma	0.000	0.998	0.002
N34.0 Urethral abscess	0.000	0.998	0.001
S71.7 Multiple open wounds of of hip and thigh	0.000	0.998	0.001
Z73.8 Other problems related to life-management difficulty	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.001	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.998	0.002
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.998	0.002
N34.1 Nonspecific urethritis	0.000	0.998	0.001
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
C44.5 Skin of trunk	0.000	0.998	0.002
E10.9 Without complications	0.000	0.998	0.002
J03.9 Acute tonsillitis, unspecified	0.002	0.998	0.000
Z73 Problems related to life-management difficulty	0.002	0.998	0.000
M25.34 Other instability of joint (Hand)	0.000	0.998	0.002
D04.3 Skin of other and unspecified parts of face	0.000	0.998	0.001
E34.8 Other specified endocrine disorders	0.001	0.998	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.002	0.998	0.000
E11.4 With neurological complications	0.000	0.999	0.001
L29.2 Pruritus vulvae	0.001	0.999	0.000
M99.8 Other biomechanical lesions	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
N82.0 Vesicovaginal fistula	0.000	0.999	0.001
T87.4 Infection of amputation stump	0.000	0.999	0.001
Z42.0 Follow-up care involving plastic surgery of head and neck	0.001	0.999	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.999	0.001
C80.9 Malignant neoplasm, unspecified	0.000	0.999	0.001
D04.5 Skin of trunk	0.000	0.999	0.001
D04.1 Skin of eyelid, including canthus	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.001	0.999	0.000
N82.4 Other female intestinal-genital tract fistulae	0.000	0.999	0.001
S80 Superficial injury of lower leg	0.001	0.999	0.000
Y53.4 Other laxatives	0.001	0.999	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.001	0.999	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.001	0.999	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
S82.21 Fracture of shaft of tibia (open)	0.001	0.999	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.999	0.000
G72.9 Myopathy, unspecified	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.001
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.999	0.001
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.999	0.000
Z73.5 Social role conflict, not elsewhere classified	0.001	0.999	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.001	0.999	0.000
Z73.2 Lack of relaxation and leisure	0.001	0.999	0.000
Z73.1 Accentuation of personality traits	0.001	0.999	0.000
Z73.0 Burn-out	0.001	0.999	0.000
D32.9 Meninges, unspecified	0.000	0.999	0.001
N82.5 Female genital tract-skin fistulae	0.000	0.999	0.001
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.999	0.001
S63.2 Multiple dislocations of fingers	0.001	0.999	0.000
Z73.6 Limitation of activities due to disability	0.001	0.999	0.000
R80 Isolated proteinuria	0.000	0.999	0.001
M99.89 Other biomechanical lesions (Abdomen and other)	0.001	0.999	0.000
M99.88 Other biomechanical lesions (Rib cage)	0.001	0.999	0.000
M99.87 Other biomechanical lesions (Upper extremity)	0.001	0.999	0.000
M99.86 Other biomechanical lesions (Lower extremity)	0.001	0.999	0.000
M99.85 Other biomechanical lesions (Pelvic region)	0.001	0.999	0.000
M99.84 Other biomechanical lesions (Sacral region)	0.001	0.999	0.000
M99.82 Other biomechanical lesions (Thoracic region)	0.001	0.999	0.000
M99.81 Other biomechanical lesions (Cervical region)	0.001	0.999	0.000
M99.80 Other biomechanical lesions (Head region)	0.001	0.999	0.000
D04.9 Skin, unspecified	0.000	0.999	0.001
D43.4 Spinal cord	0.000	0.999	0.001
N82 Fistulae involving female genital tract	0.000	0.999	0.001
H44.0 Purulent endophthalmitis	0.001	0.999	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.999	0.000
Y89.9 Sequelae of unspecified external cause	0.001	0.999	0.000
E23.7 Disorder of pituitary gland, unspecified	0.001	0.999	0.000
K05.1 Chronic gingivitis	0.000	0.999	0.001
K86.9 Disease of pancreas, unspecified	0.000	0.999	0.001
M99 Biomechanical lesions, not elsewhere classified	0.001	0.999	0.000
S63.1 Dislocation finger	0.001	0.999	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.001	0.999	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.999	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.999	0.001
Y88 Sequelae of surgical and medical care as external cause	0.001	0.999	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.001	0.999	0.000
J85.2 Abscess of lung without pneumonia	0.001	0.999	0.000
K35.3 Acute appendicitis with localized peritonitis	0.001	0.999	0.000
S51.8 Open wound of other parts of forearm	0.000	0.999	0.001
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.001
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.000	0.999	0.001
N82.8 Other female genital tract fistulae	0.000	0.999	0.001
N82.2 Fistula of vagina to small intestine	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
S51.0 Open wound of elbow	0.000	0.999	0.001
S63.0 Dislocation of wrist	0.001	0.999	0.000
E22 Hyperfunction of pituitary gland	0.001	0.999	0.000
D04.4 Skin of scalp and neck	0.000	0.999	0.001
K51.5 Mucosal proctocolitis	0.001	0.999	0.000
N82.9 Female genital tract fistula, unspecified	0.000	0.999	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.001	0.999	0.000
H80 Otosclerosis	0.001	0.999	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.999	0.001
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.999	0.000
J33.9 Nasal polyp, unspecified	0.000	0.999	0.001
M99.9 Biomechanical lesion, unspecified	0.001	0.999	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.999	0.000
M99.4 Connective tissue stenosis of neural canal	0.001	0.999	0.000
M99.3 Osseous stenosis of neural canal	0.001	0.999	0.000
M99.2 Subluxation stenosis of neural canal	0.001	0.999	0.000
M99.1 Subluxation complex (vertebral)	0.001	0.999	0.000
M99.0 Segmental and somatic dysfunction	0.001	0.999	0.000
T59.9 Gases, fumes and vapours, unspecified	0.000	0.999	0.001
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.999	0.000
K11.5 Sialolithiasis	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.999	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.999	0.001
D43.1 Brain, infratentorial	0.000	0.999	0.001
E05.9 Thyrotoxicosis, unspecified	0.001	0.999	0.000
I95.2 Hypotension due to drugs	0.000	0.999	0.001
J94.2 Haemothorax	0.001	0.999	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.001	0.999	0.000
S80.7 Multiple superficial injuries of lower leg	0.001	0.999	0.000
T59.7 Carbon dioxide	0.000	0.999	0.001
T59.6 Hydrogen sulphide	0.000	0.999	0.001
T59.5 Fluorine gas and hydrogen fluoride	0.000	0.999	0.001
T59.4 Chlorine gas	0.000	0.999	0.001
T59.3 Lachrymogenic gas	0.000	0.999	0.001
T59.2 Formaldehyde	0.000	0.999	0.001
T59.1 Sulphur dioxide	0.000	0.999	0.001
T59.0 Nitrogen oxides	0.000	0.999	0.001
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.999	0.000
H04.9 Disorder of lachrymal system, unspecified	0.001	0.999	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.999	0.001
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.001	0.999	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations