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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs187607716
log Bayes Factor = 0.281898
Chromosome 12   position 91,487,517  (GRCh37) Explore rs187607716 on Ensembl!
Variant rs187607716 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.543 0.457
I25.1 Atherosclerotic heart disease
0.000 0.546 0.454
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.562 0.438
I20-I25 Ischaemic heart diseases
0.000 0.577 0.423
I20 Angina pectoris
0.000 0.586 0.414
I25.2 Old myocardial infarction
0.000 0.593 0.407
I20.0 Unstable angina
0.000 0.598 0.402
I20.9 Angina pectoris, unspecified
0.000 0.656 0.344
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.660 0.340
I25.6 Silent myocardial ischaemia
0.000 0.672 0.328
I25.5 Ischaemic cardiomyopathy
0.000 0.672 0.328
I25.4 Coronary artery aneurysm
0.000 0.672 0.328
I25.3 Aneurysm of heart
0.000 0.672 0.328
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.672 0.328
I21 Acute myocardial infarction
0.000 0.679 0.321
I20.8 Other forms of angina pectoris
0.000 0.693 0.307
I24 Other acute ischaemic heart diseases
0.000 0.697 0.303
I23 Certain current complications following acute myocardial infarction
0.000 0.697 0.303
I22 Subsequent myocardial infarction
0.000 0.697 0.303
I20.1 Angina pectoris with documented spasm
0.000 0.703 0.297
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.731 0.269
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.770 0.230
I21.4 Acute subendocardial myocardial infarction
0.000 0.770 0.230
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.770 0.230
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.770 0.230
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.782 0.218
I22.8 Subsequent myocardial infarction of other sites
0.000 0.782 0.218
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.782 0.218
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.782 0.218
I23.8 Other current complications following acute myocardial infarction
0.000 0.782 0.218
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.782 0.218
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.782 0.218
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.782 0.218
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.782 0.218
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.782 0.218
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.782 0.218
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.782 0.218
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.782 0.218
I24.8 Other forms of acute ischaemic heart disease
0.000 0.782 0.218
I24.1 Dressler's syndrome
0.000 0.782 0.218
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.782 0.218
I21.9 Acute myocardial infarction, unspecified
0.000 0.785 0.215
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.788 0.212
Chapter IX Diseases of the circulatory system
0.000 0.910 0.090
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.927 0.073
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.928 0.072
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.935 0.065
I00-I02 Acute rheumatic fever
0.000 0.935 0.065
I60-I69 Cerebrovascular diseases
0.000 0.936 0.064
I30-I52 Other forms of heart disease
0.000 0.937 0.063
I26 Pulmonary embolism
0.000 0.939 0.061
I73 Other peripheral vascular diseases
0.000 0.939 0.061
I05-I09 Chronic rheumatic heart diseases
0.000 0.941 0.059
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.946 0.054
I73.9 Peripheral vascular disease, unspecified
0.000 0.947 0.053
I45 Other conduction disorders
0.000 0.947 0.053
I28 Other diseases of pulmonary vessels
0.000 0.947 0.052
I27 Other pulmonary heart diseases
0.000 0.947 0.052
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.948 0.052
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.948 0.052
I78 Diseases of capillaries
0.000 0.948 0.052
I72 Other aneurysm
0.000 0.948 0.052
I70 Atherosclerosis
0.000 0.948 0.052
I71 Aortic aneurysm and dissection
0.000 0.948 0.052
I77 Other disorders of arteries and arterioles
0.000 0.949 0.051
I50 Heart failure
0.000 0.949 0.051
I47 Paroxysmal tachycardia
0.000 0.950 0.050
I74 Arterial embolism and thrombosis
0.000 0.950 0.050
I95 Hypotension
0.000 0.953 0.047
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.953 0.047
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.953 0.047
I99 Other and unspecified disorders of circulatory system
0.000 0.953 0.047
I02 Rheumatic chorea
0.000 0.953 0.046
I01 Rheumatic fever with heart involvement
0.000 0.953 0.046
I00 Rheumatic fever without mention of heart involvement
0.000 0.953 0.046
I34 Nonrheumatic mitral valve disorders
0.000 0.954 0.046
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.954 0.046
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.954 0.046
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.954 0.046
I62 Other nontraumatic intracranial haemorrhage
0.000 0.954 0.046
I61 Intracerebral haemorrhage
0.000 0.954 0.046
I60 Subarachnoid haemorrhage
0.000 0.954 0.046
I69 Sequelae of cerebrovascular disease
0.000 0.954 0.046
I52 Other heart disorders in diseases classified elsewhere
0.000 0.954 0.045
I48 Atrial fibrillation and flutter
0.000 0.954 0.045
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.954 0.045
I41 Myocarditis in diseases classified elsewhere
0.000 0.954 0.045
I40 Acute myocarditis
0.000 0.954 0.045
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.954 0.045
I37 Pulmonary valve disorders
0.000 0.954 0.045
I36 Nonrheumatic tricuspid valve disorders
0.000 0.954 0.045
I33 Acute and subacute endocarditis
0.000 0.954 0.045
I32 Pericarditis in diseases classified elsewhere
0.000 0.954 0.045
I31 Other diseases of pericardium
0.000 0.954 0.045
I30 Acute pericarditis
0.000 0.954 0.045
I38 Endocarditis, valve unspecified
0.000 0.954 0.045
I63 Cerebral infarction
0.000 0.955 0.045
I45.1 Other and unspecified right bundle-branch block
0.000 0.955 0.045
I42 Cardiomyopathy
0.000 0.955 0.045
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.956 0.044
I35 Nonrheumatic aortic valve disorders
0.000 0.956 0.044
I73.8 Other specified peripheral vascular diseases
0.000 0.956 0.044
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.956 0.044
I50.0 Congestive heart failure
0.000 0.957 0.043
I73.0 Raynaud's syndrome
0.000 0.957 0.043
I09 Other rheumatic heart diseases
0.000 0.957 0.042
I07 Rheumatic tricuspid valve diseases
0.000 0.957 0.042
I06 Rheumatic aortic valve diseases
0.000 0.957 0.042
I05 Rheumatic mitral valve diseases
0.000 0.957 0.042
I46 Cardiac arrest
0.000 0.957 0.042
I10-I15 Hypertensive diseases
0.000 0.958 0.042
I50.9 Heart failure, unspecified
0.000 0.959 0.041
I51 Complications and ill-defined descriptions of heart disease
0.000 0.959 0.040
I47.1 Supraventricular tachycardia
0.000 0.960 0.040
I95.1 Orthostatic hypotension
0.000 0.962 0.038
I44 Atrioventricular and left bundle-branch block
0.000 0.962 0.038
I45.9 Conduction disorder, unspecified
0.000 0.962 0.038
I45.8 Other specified conduction disorders
0.000 0.962 0.038
I45.6 Preexcitation syndrome
0.000 0.962 0.038
I45.5 Other specified heart block
0.000 0.962 0.038
I45.4 Nonspecific intraventricular block
0.000 0.962 0.038
I45.3 Trifascicular block
0.000 0.962 0.038
I45.2 Bifascicular block
0.000 0.962 0.038
I45.0 Right fascicular block
0.000 0.962 0.038
I27.9 Pulmonary heart disease, unspecified
0.000 0.962 0.038
I27.8 Other specified pulmonary heart diseases
0.000 0.962 0.038
I27.2 Other secondary pulmonary hypertension
0.000 0.962 0.038
I27.1 Kyphoscoliotic heart disease
0.000 0.962 0.038
I27.0 Primary pulmonary hypertension
0.000 0.962 0.038
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.962 0.038
I28.8 Other specified diseases of pulmonary vessels
0.000 0.962 0.038
I28.1 Aneurysm of pulmonary artery
0.000 0.962 0.038
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.962 0.038
I70.9 Generalised and unspecified atherosclerosis
0.000 0.963 0.037
I70.8 Atherosclerosis of other arteries
0.000 0.963 0.037
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.963 0.037
I70.1 Atherosclerosis of renal artery
0.000 0.963 0.037
I70.0 Atherosclerosis of aorta
0.000 0.963 0.037
I72.9 Aneurysm of unspecified site
0.000 0.963 0.037
I72.8 Aneurysm of other specified arteries
0.000 0.963 0.037
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.963 0.037
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.963 0.037
I72.4 Aneurysm of artery of lower extremity
0.000 0.963 0.037
I72.3 Aneurysm of iliac artery
0.000 0.963 0.037
I72.2 Aneurysm of renal artery
0.000 0.963 0.037
I72.1 Aneurysm of artery of upper extremity
0.000 0.963 0.037
I72.0 Aneurysm of carotid artery
0.000 0.963 0.037
I78.9 Disease of capillaries, unspecified
0.000 0.963 0.037
I78.8 Other diseases of capillaries
0.000 0.963 0.037
I78.1 Naevus, nonneoplastic
0.000 0.963 0.037
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.963 0.037
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.963 0.037
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.963 0.037
I79.1 Aortitis in diseases classified elsewhere
0.000 0.963 0.037
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.963 0.037
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.963 0.037
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.963 0.037
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.963 0.037
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.963 0.037
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.963 0.037
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.963 0.037
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.963 0.037
I71.0 Dissection of aorta [any part]
0.000 0.963 0.037
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.963 0.037
I08 Multiple valve diseases
0.000 0.963 0.037
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.963 0.037
I77.8 Other specified disorders of arteries and arterioles
0.000 0.963 0.037
I77.6 Arteritis, unspecified
0.000 0.963 0.037
I77.5 Necrosis of artery
0.000 0.963 0.037
I77.4 Coeliac artery compression syndrome
0.000 0.963 0.037
I77.3 Arterial fibromuscular dysplasia
0.000 0.963 0.037
I77.2 Rupture of artery
0.000 0.963 0.037
I77.0 Arteriovenous fistula, acquired
0.000 0.963 0.037
I77.1 Stricture of artery
0.000 0.963 0.036
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.964 0.036
I47.2 Ventricular tachycardia
0.000 0.964 0.036
I47.0 Reentry ventricular arrhythmia
0.000 0.964 0.036
I49 Other cardiac arrhythmias
0.000 0.964 0.036
K80.2 Calculus of gallbladder without cholecystitis
0.036 0.964 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.964 0.036
I74.8 Embolism and thrombosis of other arteries
0.000 0.964 0.036
I74.5 Embolism and thrombosis of iliac artery
0.000 0.964 0.036
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.964 0.036
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.964 0.036
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.964 0.036
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.964 0.036
I34.0 Mitral (valve) insufficiency
0.000 0.965 0.035
I95.8 Other hypotension
0.000 0.966 0.034
I95.2 Hypotension due to drugs
0.000 0.966 0.034
I95.0 Idiopathic hypotension
0.000 0.966 0.034
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.966 0.034
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.966 0.034
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.966 0.034
I97.1 Other functional disturbances following cardiac surgery
0.000 0.966 0.034
I97.0 Postcardiotomy syndrome
0.000 0.966 0.034
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.966 0.034
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.966 0.034
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.966 0.034
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.966 0.034
I98.0 Cardiovascular syphilis
0.000 0.966 0.034
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.966 0.033
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.966 0.033
I01.8 Other acute rheumatic heart disease
0.000 0.966 0.033
I01.2 Acute rheumatic myocarditis
0.000 0.966 0.033
I01.1 Acute rheumatic endocarditis
0.000 0.966 0.033
I01.0 Acute rheumatic pericarditis
0.000 0.966 0.033
I02.9 Rheumatic chorea without heart involvement
0.000 0.966 0.033
I02.0 Rheumatic chorea with heart involvement
0.000 0.966 0.033
I67 Other cerebrovascular diseases
0.000 0.966 0.033
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.967 0.033
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.967 0.033
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.967 0.033
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.967 0.033
I60.8 Other subarachnoid haemorrhage
0.000 0.967 0.033
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.967 0.033
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.967 0.033
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.967 0.033
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.967 0.033
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.967 0.033
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.967 0.033
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.967 0.033
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.967 0.033
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.967 0.033
I61.8 Other intracerebral haemorrhage
0.000 0.967 0.033
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.967 0.033
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.967 0.033
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.967 0.033
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.967 0.033
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.967 0.033
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.967 0.033
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.967 0.033
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.967 0.033
I62.1 Nontraumatic extradural haemorrhage
0.000 0.967 0.033
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.967 0.033
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.967 0.033
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.967 0.033
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.967 0.033
I65.2 Occlusion and stenosis of carotid artery
0.000 0.967 0.033
I65.1 Occlusion and stenosis of basilar artery
0.000 0.967 0.033
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.967 0.033
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.967 0.033
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.967 0.033
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.967 0.033
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.967 0.033
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.967 0.033
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.967 0.033
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.967 0.033
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.967 0.033
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.967 0.033
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I68.0 Cerebral amyloid angiopathy
0.000 0.967 0.033
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.967 0.033
I69.3 Sequelae of cerebral infarction
0.000 0.967 0.033
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.967 0.033
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.967 0.033
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.967 0.033
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.967 0.033
I30.9 Acute pericarditis, unspecified
0.000 0.967 0.033
I30.8 Other forms of acute pericarditis
0.000 0.967 0.033
I30.1 Infective pericarditis
0.000 0.967 0.033
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.967 0.033
I31.9 Disease of pericardium, unspecified
0.000 0.967 0.033
I31.8 Other specified diseases of pericardium
0.000 0.967 0.033
I31.3 Pericardial effusion (noninflammatory)
0.000 0.967 0.033
I31.2 Haemopericardium, not elsewhere classified
0.000 0.967 0.033
I31.1 Chronic constrictive pericarditis
0.000 0.967 0.033
I31.0 Chronic adhesive pericarditis
0.000 0.967 0.033
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.967 0.033
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.967 0.033
I33.9 Acute endocarditis, unspecified
0.000 0.967 0.033
I33.0 Acute and subacute infective endocarditis
0.000 0.967 0.033
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.967 0.033
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.967 0.033
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.967 0.033
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.967 0.033
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.967 0.033
I37.9 Pulmonary valve disorder, unspecified
0.000 0.967 0.033
I37.8 Other pulmonary valve disorders
0.000 0.967 0.033
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.967 0.033
I37.1 Pulmonary valve insufficiency
0.000 0.967 0.033
I37.0 Pulmonary valve stenosis
0.000 0.967 0.033
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.967 0.033
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.967 0.033
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.967 0.033
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.967 0.033
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.967 0.033
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.967 0.033
I40.9 Acute myocarditis, unspecified
0.000 0.967 0.033
I40.8 Other acute myocarditis
0.000 0.967 0.033
I40.1 Isolated myocarditis
0.000 0.967 0.033
I40.0 Infective myocarditis
0.000 0.967 0.033
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.967 0.033
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.967 0.033
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.967 0.033
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.967 0.033
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.967 0.033
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.967 0.033
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.967 0.033
I48.4 Atypical atrial flutter
0.000 0.967 0.033
I48.3 Typical atrial flutter
0.000 0.967 0.033
I48.2 Chronic atrial fibrillation
0.000 0.967 0.033
I48.1 Persistent atrial fibrillation
0.000 0.967 0.033
I48.0 Paroxysmal atrial fibrillation
0.000 0.967 0.033
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.967 0.033
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.967 0.033
I63.8 Other cerebral infarction
0.000 0.967 0.032
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.967 0.032
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.967 0.032
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.967 0.032
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.967 0.032
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.967 0.032
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.967 0.032
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.967 0.032
I35.1 Aortic (valve) insufficiency
0.000 0.967 0.033
I42.9 Cardiomyopathy, unspecified
0.000 0.968 0.032
I42.8 Other cardiomyopathies
0.000 0.968 0.032
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.968 0.032
I42.6 Alcoholic cardiomyopathy
0.000 0.968 0.032
I42.5 Other restrictive cardiomyopathy
0.000 0.968 0.032
I42.4 Endocardial fibroelastosis
0.000 0.968 0.032
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.968 0.032
I42.2 Other hypertrophic cardiomyopathy
0.000 0.968 0.032
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.968 0.032
I34.1 Mitral (valve) prolapse
0.000 0.968 0.032
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.968 0.032
I12 Hypertensive renal disease
0.000 0.968 0.032
I35.9 Aortic valve disorder, unspecified
0.000 0.968 0.032
I35.8 Other aortic valve disorders
0.000 0.968 0.032
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.968 0.032
I63.9 Cerebral infarction, unspecified
0.000 0.968 0.032
I42.0 Dilated cardiomyopathy
0.000 0.969 0.031
I05.9 Mitral valve disease, unspecified
0.000 0.969 0.031
I05.8 Other mitral valve diseases
0.000 0.969 0.031
I05.2 Mitral stenosis with insufficiency
0.000 0.969 0.031
I05.1 Rheumatic mitral insufficiency
0.000 0.969 0.031
I05.0 Mitral stenosis
0.000 0.969 0.031
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.969 0.031
I06.8 Other rheumatic aortic valve diseases
0.000 0.969 0.031
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.969 0.031
I06.1 Rheumatic aortic insufficiency
0.000 0.969 0.031
I06.0 Rheumatic aortic stenosis
0.000 0.969 0.031
I07.9 Tricuspid valve disease, unspecified
0.000 0.969 0.031
I07.8 Other tricuspid valve diseases
0.000 0.969 0.031
I07.2 Tricuspid stenosis with insufficiency
0.000 0.969 0.031
I07.1 Tricuspid insufficiency
0.000 0.969 0.031
I07.0 Tricuspid stenosis
0.000 0.969 0.031
I09.9 Rheumatic heart disease, unspecified
0.000 0.969 0.031
I09.8 Other specified rheumatic heart diseases
0.000 0.969 0.031
I09.2 Chronic rheumatic pericarditis
0.000 0.969 0.031
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.969 0.031
I09.0 Rheumatic myocarditis
0.000 0.969 0.031
I46.1 Sudden cardiac death, so described
0.000 0.969 0.030
I46.0 Cardiac arrest with successful resuscitation
0.000 0.969 0.030
I15 Secondary hypertension
0.000 0.970 0.030
I13 Hypertensive heart and renal disease
0.000 0.970 0.030
I11 Hypertensive heart disease
0.000 0.970 0.030
I51.8 Other ill-defined heart diseases
0.000 0.970 0.029
I50.1 Left ventricular failure
0.000 0.971 0.029
I51.9 Heart disease, unspecified
0.000 0.971 0.029
I51.6 Cardiovascular disease, unspecified
0.000 0.971 0.029
I51.5 Myocardial degeneration
0.000 0.971 0.029
I51.4 Myocarditis, unspecified
0.000 0.971 0.029
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.971 0.029
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.971 0.029
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.971 0.029
I51.0 Cardiac septal defect, acquired
0.000 0.971 0.029
I35.0 Aortic (valve) stenosis
0.000 0.971 0.029
I95.9 Hypotension, unspecified
0.000 0.971 0.029
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.972 0.028
I46.9 Cardiac arrest, unspecified
0.000 0.972 0.027
I44.6 Other and unspecified fascicular block
0.000 0.972 0.027
I44.5 Left posterior fascicular block
0.000 0.972 0.027
I44.4 Left anterior fascicular block
0.000 0.972 0.027
I44.3 Other and unspecified atrioventricular block
0.000 0.972 0.027
I44.2 Atrioventricular block, complete
0.000 0.972 0.027
I44.1 Atrioventricular block, second degree
0.000 0.972 0.027
I44.0 Atrioventricular block, first degree
0.000 0.973 0.027
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.973 0.027
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.973 0.027
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.973 0.027
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.973 0.027
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.973 0.027
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.973 0.027
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.973 0.027
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.973 0.027
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.973 0.027
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.973 0.027
I08.9 Multiple valve disease, unspecified
0.000 0.973 0.027
I08.8 Other multiple valve diseases
0.000 0.973 0.027
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.973 0.027
I49.5 Sick sinus syndrome
0.000 0.974 0.026
I49.4 Other and unspecified premature depolarisation
0.000 0.974 0.026
I49.2 Junctional premature depolarisation
0.000 0.974 0.026
I49.1 Atrial premature depolarisation
0.000 0.974 0.026
I49.0 Ventricular fibrillation and flutter
0.000 0.974 0.026
I49.9 Cardiac arrhythmia, unspecified
0.000 0.974 0.026
I08.0 Disorders of both mitral and aortic valves
0.000 0.975 0.024
I12.0 Hypertensive renal disease with renal failure
0.000 0.975 0.024
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.976 0.024
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.976 0.024
I67.5 Moyamoya disease
0.000 0.976 0.024
I67.4 Hypertensive encephalopathy
0.000 0.976 0.024
I67.3 Progressive vascular leukoencephalopathy
0.000 0.976 0.024
I67.1 Cerebral aneurysm, nonruptured
0.000 0.976 0.024
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.976 0.024
I51.7 Cardiomegaly
0.000 0.976 0.024
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.977 0.023
I88 Nonspecific lymphadenitis
0.000 0.977 0.023
I87 Other disorders of veins
0.000 0.977 0.023
I86 Varicose veins of other sites
0.000 0.977 0.023
I85 Oesophageal varices
0.000 0.977 0.023
I82 Other venous embolism and thrombosis
0.000 0.977 0.023
I81 Portal vein thrombosis
0.000 0.977 0.023
I12.9 Hypertensive renal disease without renal failure
0.000 0.977 0.023
I67.9 Cerebrovascular disease, unspecified
0.000 0.977 0.023
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.977 0.022
I49.8 Other specified cardiac arrhythmias
0.000 0.978 0.022
I49.3 Ventricular premature depolarisation
0.000 0.978 0.022
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.978 0.022
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.978 0.022
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.978 0.022
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.978 0.022
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.978 0.022
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.978 0.022
I15.9 Seconday hypertension, unspecified
0.000 0.978 0.022
I15.8 Other secondary hypertension
0.000 0.978 0.022
I15.2 Hypertension secondary to endocrine disorders
0.000 0.978 0.022
I15.1 Hypertension secondary to other renal disorders
0.000 0.978 0.022
I15.0 Renovascular hypertension
0.000 0.978 0.022
I80 Phlebitis and thrombophlebitis
0.000 0.978 0.022
I67.8 Other specified cerebrovascular diseases
0.000 0.979 0.021
I44.7 Left bundle-branch block, unspecified
0.000 0.979 0.020
I67.2 Cerebral atherosclerosis
0.001 0.980 0.019
K80 Cholelithiasis
0.020 0.980 0.000
I83 Varicose veins of lower extremities
0.000 0.981 0.019
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.983 0.017
I82.8 Embolism and thrombosis of other specified veins
0.000 0.983 0.017
I82.3 Embolism and thrombosis of renal vein
0.000 0.983 0.017
I82.2 Embolism and thrombosis of vena cava
0.000 0.983 0.017
I82.1 Thrombophlebitis migrans
0.000 0.983 0.017
I82.0 Budd-Chiari syndrome
0.000 0.983 0.017
I85.9 Oesophageal varices without bleeding
0.000 0.983 0.017
I85.0 Oesophageal varices with bleeding
0.000 0.983 0.017
I86.8 Varicose veins of other specified sites
0.000 0.983 0.017
I86.4 Gastric varices
0.000 0.983 0.017
I86.3 Vulval varices
0.000 0.983 0.017
I86.2 Pelvic varices
0.000 0.983 0.017
I86.1 Scrotal varices
0.000 0.983 0.017
I86.0 Sublingual varices
0.000 0.983 0.017
I87.9 Disorder of vein, unspecified
0.000 0.983 0.017
I87.8 Other specified disorders of veins
0.000 0.983 0.017
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.983 0.017
I87.1 Compression of vein
0.000 0.983 0.017
I87.0 Postphlebitic syndrome
0.000 0.983 0.017
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.983 0.017
I88.8 Other nonspecific lymphadenitis
0.000 0.983 0.017
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.983 0.017
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.983 0.017
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.983 0.017
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.983 0.017
I89.1 Lymphangitis
0.000 0.983 0.017
I89.0 Lymphoedema, not elsewhere classified
0.000 0.983 0.017
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.984 0.016
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.984 0.016
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.984 0.016
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.984 0.016
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.984 0.016
K80.0 Calculus of gallbladder with acute cholecystitis
0.015 0.985 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.985 0.014
K80.3 Calculus of bile duct with cholangitis
0.014 0.986 0.000
K80.8 Other cholelithiasis
0.014 0.986 0.000
K80.4 Calculus of bile duct with cholecystitis
0.014 0.986 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.986 0.014
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.986 0.014
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.986 0.014
K80.1 Calculus of gallbladder with other cholecystitis
0.013 0.987 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.012 0.987 0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.010 0.989 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.991 0.009
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.009 0.991 0.000
K85 Acute pancreatitis
0.008 0.992 0.000
K81 Cholecystitis
0.007 0.993 0.000
I84 Haemorrhoids
0.000 0.993 0.007
K86 Other diseases of pancreas
0.007 0.993 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.007 0.993 0.000
K82 Other diseases of gallbladder
0.007 0.993 0.000
K81.1 Chronic cholecystitis
0.006 0.993 0.000
K85.9 Acute pancreatitis, unspecified
0.006 0.994 0.000
I84.5 External haemorrhoids without complication
0.000 0.994 0.006
K83 Other diseases of biliary tract
0.006 0.994 0.000
K85.8 Other acute pancreatitis
0.006 0.994 0.000
K85.3 Drug-induced acute pancreatitis
0.006 0.994 0.000
K85.2 Alcohol-induced acute pancreatitis
0.006 0.994 0.000
K85.1 Biliary acute pancreatitis
0.006 0.994 0.000
K85.0 Idiopathic acute pancreatitis
0.006 0.994 0.000
K81.9 Cholecystitis, unspecified
0.005 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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