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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs187700680
log Bayes Factor = 24.0087
Chromosome 8   position 15,377,498  (GRCh37) Explore rs187700680 on Ensembl!
Variant rs187700680 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
I20.9 Angina pectoris, unspecified
0.998 0.002 0.000
I50.1 Left ventricular failure
0.997 0.003 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
I21 Acute myocardial infarction
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.995 0.005 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.995 0.005 0.000
I25.2 Old myocardial infarction
0.995 0.005 0.000
Z95.1 Presence of aortocoronary bypass graft
0.994 0.006 0.000
I50.9 Heart failure, unspecified
0.993 0.007 0.000
I21.9 Acute myocardial infarction, unspecified
0.990 0.010 0.000
I50.0 Congestive heart failure
0.982 0.018 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.982 0.018 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
Chapter XX External causes of morbidity and mortality
0.966 0.034 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.963 0.037 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.956 0.044 0.000
I20.8 Other forms of angina pectoris
0.953 0.047 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.947 0.053 0.000
C64-C68 Malignant neoplasms of urinary tract
0.943 0.057 0.000
Chapter X Diseases of the respiratory system
0.941 0.059 0.000
J09-J18 Influenza and pneumonia
0.937 0.063 0.000
J18 Pneumonia, organism unspecified
0.933 0.067 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.929 0.071 0.000
Z95.0 Presence of cardiac pacemaker
0.928 0.072 0.000
J18.9 Pneumonia, unspecified
0.920 0.080 0.000
I51 Complications and ill-defined descriptions of heart disease
0.919 0.081 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.918 0.082 0.000
I22 Subsequent myocardial infarction
0.915 0.085 0.000
Chapter VIII Diseases of the ear and mastoid process
0.910 0.090 0.000
C15-C26 Malignant neoplasms of digestive organs
0.908 0.092 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.908 0.092 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.903 0.097 0.000
Z60 Problems related to social environment
0.902 0.098 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.900 0.100 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.896 0.104 0.000
G20-G26 Extrapyramidal and movement disorders
0.895 0.105 0.000
C67 Malignant neoplasm of bladder
0.891 0.109 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.889 0.111 0.000
Z83 Family history of other specific disorders
0.883 0.117 0.000
J18.1 Lobar pneumonia, unspecified
0.881 0.119 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.879 0.121 0.000
I25.5 Ischaemic cardiomyopathy
0.874 0.126 0.000
I95 Hypotension
0.873 0.127 0.000
G90-G99 Other disorders of the nervous system
0.872 0.128 0.000
I47 Paroxysmal tachycardia
0.872 0.128 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
Z60.2 Living alone
0.871 0.129 0.000
E20-E35 Disorders of other endocrine glands
0.867 0.133 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.866 0.134 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.865 0.135 0.000
E10-E14 Diabetes mellitus
0.864 0.136 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.861 0.139 0.000
Z92 Personal history of medical treatment
0.860 0.140 0.000
I38 Endocarditis, valve unspecified
0.859 0.141 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.858 0.142 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.858 0.142 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.857 0.143 0.000
Chapter I Certain infectious and parasitic diseases
0.856 0.144 0.000
H90-H95 Other disorders of ear
0.855 0.145 0.000
I95.1 Orthostatic hypotension
0.854 0.146 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.853 0.147 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.849 0.151 0.000
I42 Cardiomyopathy
0.846 0.154 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.843 0.157 0.000
I24 Other acute ischaemic heart diseases
0.838 0.161 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.833 0.167 0.000
D00-D09 In situ neoplasms
0.832 0.168 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.826 0.174 0.000
I47.2 Ventricular tachycardia
0.825 0.175 0.000
Z94 Transplanted organ and tissue status
0.823 0.177 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.823 0.177 0.000
Z89 Acquired absence of limb
0.817 0.183 0.000
J90-J94 Other diseases of pleura
0.815 0.185 0.000
E65-E68 Obesity and other hyperalimentation
0.813 0.187 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.813 0.187 0.000
I51.7 Cardiomegaly
0.809 0.191 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
G81 Hemiplegia
0.804 0.196 0.000
Y60.0 During surgical operation
0.802 0.198 0.000
Z81 Family history of mental and behavioural disorders
0.799 0.201 0.000
O36 Maternal care for other known or suspected foetal problems
0.798 0.202 0.000
Z92.3 Personal history of irradiation
0.797 0.203 0.000
G20 Parkinson's disease
0.797 0.203 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.796 0.204 0.000
I51.9 Heart disease, unspecified
0.792 0.208 0.000
E11 Non-insulin-dependent diabetes mellitus
0.791 0.209 0.000
Z85 Personal history of malignant neoplasm
0.791 0.209 0.000
D45 Polycythaemia vera
0.788 0.212 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.788 0.212 0.000
I25.3 Aneurysm of heart
0.786 0.214 0.000
Z83.3 Family history of diabetes mellitus
0.785 0.215 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.783 0.217 0.000
A00-A09 Intestinal infectious diseases
0.782 0.218 0.000
Z95.3 Presence of xenogenic heart valve
0.779 0.221 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.779 0.221 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.777 0.223 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.777 0.223 0.000
E70-E90 Metabolic disorders
0.776 0.224 0.000
D37.4 Colon
0.776 0.224 0.000
O47 False labour
0.775 0.225 0.000
Z95.4 Presence of other heart-valve replacement
0.770 0.230 0.000
Z95.2 Presence of prosthetic heart valve
0.770 0.230 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.769 0.231 0.000
C18 Malignant neoplasm of colon
0.769 0.231 0.000
I35 Nonrheumatic aortic valve disorders
0.768 0.232 0.000
H91 Other hearing loss
0.768 0.232 0.000
G90 Disorders of autonomic nervous system
0.767 0.233 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.765 0.235 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.765 0.235 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.764 0.235 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.764 0.236 0.000
C67.2 Lateral wall of bladder
0.761 0.239 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.759 0.241 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.757 0.243 0.000
Z83.5 Family history of eye and ear disorders
0.757 0.243 0.000
J86 Pyothorax
0.755 0.245 0.000
C78.7 Secondary malignant neoplasm of liver
0.754 0.246 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.754 0.246 0.000
G81.9 Hemiplegia, unspecified
0.751 0.249 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.747 0.253 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.747 0.253 0.000
G25 Other extrapyramidal and movement disorders
0.746 0.254 0.000
E22 Hyperfunction of pituitary gland
0.743 0.257 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.742 0.258 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.742 0.258 0.000
I77 Other disorders of arteries and arterioles
0.740 0.260 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.740 0.260 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.739 0.261 0.000
C77.9 Lymph node, unspecified
0.739 0.261 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.739 0.261 0.000
Z82.3 Family history of stroke
0.739 0.261 0.000
I30 Acute pericarditis
0.737 0.262 0.000
V20-V29 Motorcycle rider injured in transport accident
0.737 0.263 0.000
A04 Other bacterial intestinal infections
0.737 0.263 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.736 0.264 0.000
C79 Secondary malignant neoplasm of other sites
0.736 0.264 0.000
J11 Influenza, virus not identified
0.735 0.264 0.000
I51.0 Cardiac septal defect, acquired
0.735 0.265 0.000
Z57 Occupational exposure to risk-factors
0.735 0.265 0.000
Z97 Presence of other devices
0.734 0.266 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.734 0.266 0.000
C66 Malignant neoplasm of ureter
0.733 0.267 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.732 0.268 0.000
Y43 Primarily systemic agents
0.729 0.271 0.000
C67.5 Bladder neck
0.728 0.272 0.000
C77.0 Lymph nodes of head, face and neck
0.728 0.272 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.725 0.275 0.000
C67.1 Dome of bladder
0.725 0.275 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.723 0.277 0.000
B25-B34 Other viral diseases
0.723 0.277 0.000
J93 Pneumothorax
0.721 0.279 0.000
C78.0 Secondary malignant neoplasm of lung
0.721 0.279 0.000
Y60.4 During endoscopic examination
0.720 0.280 0.000
D05 Carcinoma in situ of breast
0.719 0.281 0.000
C67.6 Ureteric orifice
0.719 0.281 0.000
E11.4 With neurological complications
0.718 0.282 0.000
Z98 Other postsurgical states
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Q80-Q89 Other congenital malformations
0.716 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
E11.3 With ophthalmic complications
0.715 0.285 0.000
Y52 Agents primarily affecting the cardiovascular system
0.714 0.286 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.714 0.286 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.714 0.286 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.714 0.286 0.000
Z84 Family history of other conditions
0.713 0.286 0.000
C25 Malignant neoplasm of pancreas
0.713 0.287 0.000
H92 Otalgia and effusion of ear
0.711 0.289 0.000
C67.4 Posterior wall of bladder
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
Chapter XXII Codes for special purposes
0.708 0.292 0.000
I24.8 Other forms of acute ischaemic heart disease
0.706 0.294 0.000
H91.9 Hearing loss, unspecified
0.705 0.295 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.704 0.296 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.704 0.296 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.704 0.296 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.704 0.296 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.704 0.296 0.000
D47.2 Monoclonal gammopathy
0.704 0.296 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.703 0.297 0.000
D41.0 Kidney
0.703 0.297 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.702 0.298 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.702 0.298 0.000
I99 Other and unspecified disorders of circulatory system
0.701 0.298 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.299 0.000
I20.1 Angina pectoris with documented spasm
0.700 0.300 0.000
J86.9 Pyothorax without fistula
0.700 0.300 0.000
D47.1 Chronic myeloproliferative disease
0.700 0.300 0.000
C21 Malignant neoplasm of anus and anal canal
0.699 0.301 0.000
E66 Obesity
0.699 0.301 0.000
E50-E64 Other nutritional deficiencies
0.698 0.302 0.000
L20-L30 Dermatitis and eczema
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.698 0.302 0.000
O00-O08 Pregnancy with abortive outcome
0.696 0.304 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.695 0.305 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.694 0.306 0.000
I05-I09 Chronic rheumatic heart diseases
0.693 0.307 0.000
H80-H83 Diseases of inner ear
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.693 0.307 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
W50-W64 Exposure to animate mechanical forces
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V80-V89 Other land transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.690 0.309 0.000
C18.0 Caecum
0.690 0.310 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.690 0.310 0.000
Y95 Nosocomial condition
0.689 0.310 0.000
E20 Hypoparathyroidism
0.689 0.311 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.689 0.311 0.000
H60-H62 Diseases of external ear
0.689 0.311 0.000
G62 Other polyneuropathies
0.689 0.311 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.688 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.312 0.000
C78.2 Secondary malignant neoplasm of pleura
0.688 0.312 0.000
I33 Acute and subacute endocarditis
0.686 0.314 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.685 0.315 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.685 0.315 0.000
Z82.2 Family history of deafness and hearing loss
0.685 0.315 0.000
Z82.1 Family history of blindness and visual loss
0.685 0.315 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.685 0.315 0.000
Y57 Other and unspecified drugs and medicaments
0.684 0.316 0.000
Chapter VII Diseases of the eye and adnexa
0.682 0.318 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.681 0.318 0.000
E00-E07 Disorders of thyroid gland
0.680 0.320 0.000
I74 Arterial embolism and thrombosis
0.680 0.320 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.680 0.320 0.000
I20.0 Unstable angina
0.680 0.320 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.321 0.000
J95-J99 Other diseases of the respiratory system
0.679 0.321 0.000
Z65 Problems related to other psychosocial circumstances
0.679 0.321 0.000
Z64 Problems related to certain psychosocial circumstances
0.679 0.321 0.000
Z63 Other problems related to primary support group, including family circumstances
0.679 0.321 0.000
Z62 Other problems related to upbringing
0.679 0.321 0.000
Z61 Problems related to negative life events in childhood
0.679 0.321 0.000
Z59 Problems related to housing and economic circumstances
0.679 0.321 0.000
Z58 Problems related to physical environment
0.679 0.321 0.000
Z56 Problems related to employment and unemployment
0.679 0.321 0.000
Z55 Problems related to education and literacy
0.679 0.321 0.000
E10 Insulin-dependent diabetes mellitus
0.678 0.322 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.678 0.322 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.676 0.324 0.000
C65 Malignant neoplasm of renal pelvis
0.676 0.324 0.000
Z94.0 Kidney transplant status
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.674 0.325 0.000
D41.4 Bladder
0.674 0.325 0.000
G95 Other diseases of spinal cord
0.674 0.326 0.000
G63.2 Diabetic polyneuropathy
0.674 0.326 0.000
L03 Cellulitis
0.674 0.326 0.000
J94 Other pleural conditions
0.673 0.327 0.000
I42.9 Cardiomyopathy, unspecified
0.672 0.328 0.000
C77.5 Intrapelvic lymph nodes
0.672 0.328 0.000
J17 Pneumonia in diseases classified elsewhere
0.671 0.328 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.671 0.328 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.671 0.328 0.000
J12 Viral pneumonia, not elsewhere classified
0.671 0.328 0.000
J14 Pneumonia due to Haemophilus influenzae
0.671 0.328 0.000
J09 Influenza due to certain identified influenza virus
0.671 0.328 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.672 0.328 0.000
J10 Influenza due to identified influenza virus
0.671 0.329 0.000
I60-I69 Cerebrovascular diseases
0.670 0.330 0.000
A04.5 Campylobacter enteritis
0.670 0.330 0.000
O80-O84 Delivery
0.669 0.330 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.669 0.331 0.000
J18.8 Other pneumonia, organism unspecified
0.669 0.331 0.000
J18.2 Hypostatic pneumonia, unspecified
0.669 0.331 0.000
D05.1 Intraductal carcinoma in situ
0.668 0.332 0.000
Z89.5 Acquired absence of leg at or below knee
0.668 0.332 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.666 0.334 0.000
O32.1 Maternal care for breech presentation
0.665 0.334 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.662 0.338 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.662 0.338 0.000
G83 Other paralytic syndromes
0.662 0.338 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.662 0.338 0.000
J93.9 Pneumothorax, unspecified
0.661 0.339 0.000
O36.8 Maternal care for other specified foetal problems
0.660 0.340 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.660 0.340 0.000
O36.6 Maternal care for excessive foetal growth
0.660 0.340 0.000
I51.6 Cardiovascular disease, unspecified
0.659 0.341 0.000
I51.5 Myocardial degeneration
0.659 0.341 0.000
I51.4 Myocarditis, unspecified
0.659 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.659 0.341 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.659 0.341 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.659 0.341 0.000
M86-M90 Other osteopathies
0.659 0.341 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.659 0.341 0.000
Z81.8 Family history of other mental and behavioural disorders
0.659 0.341 0.000
C77.8 Lymph nodes of multiple regions
0.658 0.342 0.000
H90 Conductive and sensorineural hearing loss
0.658 0.342 0.000
O85-O92 Complications predominantly related to the puerperium
0.658 0.342 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.657 0.343 0.000
I22.8 Subsequent myocardial infarction of other sites
0.656 0.344 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.656 0.344 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.656 0.344 0.000
E87.0 Hyperosmolality and hypernatraemia
0.656 0.344 0.000
Z80 Family history of malignant neoplasm
0.655 0.345 0.000
I34 Nonrheumatic mitral valve disorders
0.655 0.345 0.000
D37.7 Other digestive organs
0.654 0.346 0.000
W20-W49 Exposure to inanimate mechanical forces
0.653 0.346 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.651 0.349 0.000
C17 Malignant neoplasm of small intestine
0.651 0.349 0.000
C23 Malignant neoplasm of gallbladder
0.651 0.349 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.651 0.349 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.651 0.349 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.651 0.349 0.000
D47.4 Osteomyelofibrosis
0.651 0.349 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.651 0.349 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.651 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.650 0.349 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.649 0.350 0.000
Y65 Other misadventures during surgical and medical care
0.648 0.352 0.000
Y64 Contaminated medical or biological substances
0.648 0.352 0.000
Y63 Failure in dosage during surgical and medical care
0.648 0.352 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.648 0.352 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.648 0.352 0.000
Y69 Unspecified misadventure during surgical and medical care
0.648 0.352 0.000
Y66 Nonadministration of surgical and medical care
0.648 0.352 0.000
D46 Myelodysplastic syndromes
0.647 0.352 0.000
Z60.9 Problem related to social environment, unspecified
0.647 0.353 0.000
Z60.8 Other problems related to social environment
0.647 0.353 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.647 0.353 0.000
Z60.4 Social exclusion and rejection
0.647 0.353 0.000
Z60.3 Acculturation difficulty
0.647 0.353 0.000
Z60.1 Atypical parenting situation
0.647 0.353 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.647 0.353 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.646 0.354 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.645 0.354 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.645 0.354 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.645 0.354 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.645 0.355 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.644 0.355 0.000
G24 Dystonia
0.643 0.357 0.000
I10-I15 Hypertensive diseases
0.643 0.357 0.000
E27 Other disorders of adrenal gland
0.643 0.357 0.000
I42.2 Other hypertrophic cardiomyopathy
0.643 0.357 0.000
Y44 Agents primarily affecting blood constituents
0.642 0.358 0.000
I45 Other conduction disorders
0.642 0.358 0.000
G23 Other degenerative diseases of basal ganglia
0.641 0.358 0.000
G21 Secondary Parkinsonism
0.641 0.358 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.641 0.358 0.000
G22 Parkinsonism in diseases classified elsewhere
0.641 0.358 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.640 0.360 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.640 0.360 0.000
C67.8 Overlapping lesion of bladder
0.639 0.361 0.000
C67.7 Urachus
0.639 0.361 0.000
C67.3 Anterior wall of bladder
0.639 0.361 0.000
C67.0 Trigone of bladder
0.639 0.361 0.000
Y59 Other and unspecified vaccines and biological substances
0.637 0.363 0.000
Y58 Bacterial vaccines
0.637 0.363 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.637 0.363 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.637 0.363 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.637 0.363 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.637 0.363 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
Y48 Anaesthetics and therapeutic gases
0.637 0.363 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.637 0.363 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.637 0.363 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.637 0.363 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.634 0.366 0.000
C51-C58 Malignant neoplasms of female genital organs
0.634 0.366 0.000
B15-B19 Viral hepatitis
0.634 0.366 0.000
M45-M49 Spondylopathies
0.634 0.366 0.000
Z83.6 Family history of diseases of the respiratory system
0.633 0.367 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.633 0.367 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.633 0.367 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.633 0.367 0.000
M80-M85 Disorders of bone density and structure
0.633 0.367 0.000
G30-G32 Other degenerative diseases of the nervous system
0.633 0.367 0.000
M70-M79 Other soft tissue disorders
0.631 0.369 0.000
J18.0 Bronchopneumonia, unspecified
0.631 0.369 0.000
O47.9 False labour, unspecified
0.631 0.369 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.630 0.369 0.000
G80 Infantile cerebral palsy
0.630 0.370 0.000
D09 Carcinoma in situ of other and unspecified sites
0.630 0.370 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.628 0.372 0.000
C71 Malignant neoplasm of brain
0.628 0.372 0.000
E66.8 Other obesity
0.628 0.372 0.000
C77.4 Inguinal and lower limb lymph nodes
0.628 0.372 0.000
I70 Atherosclerosis
0.628 0.372 0.000
C20 Malignant neoplasm of rectum
0.627 0.373 0.000
B34 Viral infection of unspecified site
0.627 0.373 0.000
J60-J70 Lung diseases due to external agents
0.627 0.373 0.000
C22.0 Liver cell carcinoma
0.626 0.373 0.000
G61 Inflammatory polyneuropathy
0.626 0.373 0.000
H93 Other disorders of ear, not elsewhere classified
0.626 0.374 0.000
I95.8 Other hypotension
0.626 0.374 0.000
I95.0 Idiopathic hypotension
0.626 0.374 0.000
A08 Viral and other specified intestinal infections
0.626 0.374 0.000
G96 Other disorders of central nervous system
0.625 0.375 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.625 0.375 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.625 0.375 0.000
G92 Toxic encephalopathy
0.625 0.375 0.000
I47.0 Reentry ventricular arrhythmia
0.625 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.625 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.625 0.375 0.000
Q35-Q37 Cleft lip and cleft palate
0.625 0.375 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.625 0.375 0.000
Q00-Q07 Congenital malformations of the nervous system
0.625 0.375 0.000
I35.1 Aortic (valve) insufficiency
0.624 0.376 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.624 0.376 0.000
Z98.0 Intestinal bypass and anastomosis status
0.623 0.377 0.000
Z94.7 Corneal transplant status
0.623 0.377 0.000
G25.0 Essential tremor
0.622 0.378 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.622 0.378 0.000
E34 Other endocrine disorders
0.622 0.378 0.000
E32 Diseases of thymus
0.622 0.378 0.000
E31 Polyglandular dysfunction
0.622 0.378 0.000
E30 Disorders of puberty, not elsewhere classified
0.622 0.378 0.000
E26 Hyperaldosteronism
0.622 0.378 0.000
E25 Adrenogenital disorders
0.622 0.378 0.000
E24 Cushing's syndrome
0.622 0.378 0.000
C45 Mesothelioma
0.622 0.378 0.000
C18.1 Appendix
0.621 0.379 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.621 0.379 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.621 0.379 0.000
G60 Hereditary and idiopathic neuropathy
0.620 0.380 0.000
G64 Other disorders of peripheral nervous system
0.620 0.380 0.000
C77.1 Intrathoracic lymph nodes
0.620 0.380 0.000
E12 Malnutrition-related diabetes mellitus
0.619 0.381 0.000
J92 Pleural plaque
0.619 0.381 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.619 0.381 0.000
E29 Testicular dysfunction
0.618 0.382 0.000
O45 Premature separation of placenta [abruptio placentae]
0.617 0.382 0.000
O44 Placenta praevia
0.617 0.382 0.000
O43 Placental disorders
0.617 0.382 0.000
O41 Other disorders of amniotic fluid and membranes
0.617 0.382 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.617 0.382 0.000
O33 Maternal care for known or suspected disproportion
0.617 0.382 0.000
O31 Complications specific to multiple gestation
0.617 0.382 0.000
O30 Multiple gestation
0.617 0.382 0.000
O40 Polyhydramnios
0.617 0.382 0.000
Z92.9 Personal history of medical treatment, unspecified
0.617 0.383 0.000
Z92.8 Personal history of other medical treatment
0.617 0.383 0.000
Z92.5 Personal history of rehabilitation measures
0.617 0.383 0.000
G82 Paraplegia and tetraplegia
0.616 0.384 0.000
M05-M14 Inflammatory polyarthropathies
0.616 0.384 0.000
Y60.9 During unspecified surgical and medical care
0.615 0.384 0.000
Y60.8 During other surgical and medical care
0.615 0.384 0.000
Y60.7 During administration of enema
0.615 0.384 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.615 0.384 0.000
Y60.5 During heart catheterisation
0.615 0.384 0.000
Y60.3 During injection or immunisation
0.615 0.384 0.000
Y60.2 During kidney dialysis or other perfusion
0.615 0.384 0.000
Y60.1 During infusion or transfusion
0.615 0.384 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.615 0.385 0.000
B99-B99 Other infectious diseases
0.614 0.386 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.614 0.386 0.000
B65-B83 Helminthiases
0.614 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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