TreeWAS – Variant ID: rs1893261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
I20 Angina pectoris	0.997	0.003	0.000
I20.9 Angina pectoris, unspecified	0.994	0.006	0.000
I25.2 Old myocardial infarction	0.992	0.008	0.000
I22 Subsequent myocardial infarction	0.989	0.011	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.981	0.019	0.000
I20.0 Unstable angina	0.951	0.049	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.946	0.054	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.943	0.057	0.000
I25.5 Ischaemic cardiomyopathy	0.903	0.097	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.836	0.163	0.000
I23 Certain current complications following acute myocardial infarction	0.836	0.164	0.000
I25.6 Silent myocardial ischaemia	0.751	0.249	0.000
I25.3 Aneurysm of heart	0.747	0.253	0.000
I22.8 Subsequent myocardial infarction of other sites	0.731	0.269	0.000
I21 Acute myocardial infarction	0.720	0.280	0.000
I23.8 Other current complications following acute myocardial infarction	0.719	0.281	0.000
I21.4 Acute subendocardial myocardial infarction	0.685	0.315	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.651	0.348	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.599	0.400	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.599	0.400	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.599	0.400	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.599	0.400	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.599	0.400	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.599	0.400	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.599	0.400	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.598	0.402	0.000
I25.4 Coronary artery aneurysm	0.526	0.473	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.516	0.483	0.000
I20.8 Other forms of angina pectoris	0.512	0.488	0.000
H40.9 Glaucoma, unspecified	0.511	0.489	0.000
H40 Glaucoma	0.505	0.495	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.502	0.497	0.000
H40.2 Primary angle-closure glaucoma	0.502	0.498	0.000
H40.0 Glaucoma suspect	0.481	0.519	0.000
I21.9 Acute myocardial infarction, unspecified	0.406	0.594	0.000
I20.1 Angina pectoris with documented spasm	0.385	0.615	0.000
H40.8 Other glaucoma	0.375	0.625	0.000
H40.1 Primary open-angle glaucoma	0.370	0.630	0.000
I24 Other acute ischaemic heart diseases	0.362	0.638	0.000
H40.6 Glaucoma secondary to drugs	0.362	0.638	0.000
H40.4 Glaucoma secondary to eye inflammation	0.348	0.652	0.000
H40.3 Glaucoma secondary to eye trauma	0.314	0.685	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.303	0.697	0.000
I24.1 Dressler's syndrome	0.275	0.725	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.245	0.755	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.226	0.774	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.222	0.778	0.000
H40-H42 Glaucoma	0.211	0.789	0.000
H40.5 Glaucoma secondary to other eye disorders	0.194	0.806	0.000
I24.8 Other forms of acute ischaemic heart disease	0.189	0.811	0.000
H42 Glaucoma in diseases classified elsewhere	0.151	0.848	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.131	0.869	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.109	0.891	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.109	0.891	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.923	0.077
E27 Other disorders of adrenal gland	0.000	0.926	0.074
E27.1 Primary adrenocortical insufficiency	0.000	0.931	0.069
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.067	0.933	0.000
E27.2 Addisonian crisis	0.000	0.938	0.062
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.940	0.060
E27.9 Disorder of adrenal gland, unspecified	0.000	0.946	0.054
E27.5 Adrenomedullary hyperfunction	0.000	0.947	0.053
E27.0 Other adrenocortical overactivity	0.000	0.947	0.053
E20-E35 Disorders of other endocrine glands	0.000	0.948	0.052
E27.8 Other specified disorders of adrenal gland	0.000	0.952	0.048
E23 Hypofunction and other disorders of pituitary gland	0.000	0.953	0.047
E20 Hypoparathyroidism	0.000	0.954	0.046
E29 Testicular dysfunction	0.000	0.956	0.044
E24 Cushing's syndrome	0.000	0.957	0.043
E23.0 Hypopituitarism	0.000	0.957	0.043
E20.9 Hypoparathyroidism, unspecified	0.000	0.958	0.042
E26 Hyperaldosteronism	0.000	0.961	0.039
E29.1 Testicular hypofunction	0.000	0.962	0.038
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.963	0.037
E32 Diseases of thymus	0.000	0.963	0.037
E31 Polyglandular dysfunction	0.000	0.963	0.037
E30 Disorders of puberty, not elsewhere classified	0.000	0.963	0.037
E24.0 Pituitary-dependent Cushing's disease	0.000	0.964	0.036
E23.7 Disorder of pituitary gland, unspecified	0.000	0.964	0.036
E34 Other endocrine disorders	0.000	0.964	0.036
E25 Adrenogenital disorders	0.000	0.964	0.036
E23.6 Other disorders of pituitary gland	0.000	0.964	0.036
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.966	0.034
E23.1 Drug-induced hypopituitarism	0.000	0.966	0.034
E23.2 Diabetes insipidus	0.000	0.966	0.034
E20.8 Other hypoparathyroidism	0.000	0.967	0.033
E20.1 Pseudohypoparathyroidism	0.000	0.967	0.033
E20.0 Idiopathic hypoparathyroidism	0.000	0.967	0.033
B34.9 Viral infection, unspecified	0.033	0.967	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.968	0.032
E29.8 Other testicular dysfunction	0.000	0.968	0.032
E29.0 Testicular hyperfunction	0.000	0.968	0.032
E24.2 Drug-induced Cushing's syndrome	0.000	0.969	0.031
E24.8 Other Cushing's syndrome	0.000	0.969	0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.969	0.031
E24.3 Ectopic ACTH syndrome	0.000	0.969	0.031
E24.1 Nelson's syndrome	0.000	0.969	0.031
E24.9 Cushing's syndrome, unspecified	0.000	0.969	0.031
E28 Ovarian dysfunction	0.000	0.970	0.030
E26.0 Primary hyperaldosteronism	0.000	0.970	0.030
E22 Hyperfunction of pituitary gland	0.000	0.971	0.029
E26.8 Other hyperaldosteronism	0.000	0.972	0.028
E26.1 Secondary hyperaldosteronism	0.000	0.972	0.028
E34.9 Endocrine disorder, unspecified	0.000	0.972	0.028
E26.9 Hyperaldosteronism, unspecified	0.000	0.973	0.027
E30.9 Disorder of puberty, unspecified	0.000	0.973	0.027
E30.8 Other disorders of puberty	0.000	0.973	0.027
E30.1 Precocious puberty	0.000	0.973	0.027
E30.0 Delayed puberty	0.000	0.973	0.027
E31.9 Polyglandular dysfunction, unspecified	0.000	0.973	0.027
E31.8 Other polyglandular dysfunction	0.000	0.973	0.027
E31.1 Polyglandular hyperfunction	0.000	0.973	0.027
E31.0 Autoimmune polyglandular failure	0.000	0.973	0.027
E32.9 Disease of thymus, unspecified	0.000	0.973	0.027
E32.8 Other diseases of thymus	0.000	0.973	0.027
E32.1 Abscess of thymus	0.000	0.973	0.027
E32.0 Persistent hyperplasia of thymus	0.000	0.973	0.027
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.973	0.027
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.973	0.027
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.973	0.027
E34.5 Androgen resistance syndrome	0.000	0.974	0.026
E34.4 Constitutional tall stature	0.000	0.974	0.026
E34.3 Short stature, not elsewhere classified	0.000	0.974	0.026
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.974	0.026
E34.1 Other hypersecretion of intestinal hormones	0.000	0.974	0.026
E25.9 Adrenogenital disorder, unspecified	0.000	0.974	0.026
E25.8 Other adrenogenital disorders	0.000	0.974	0.026
E34.8 Other specified endocrine disorders	0.000	0.974	0.026
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.976	0.024
E34.0 Carcinoid syndrome	0.000	0.977	0.022
B34 Viral infection of unspecified site	0.022	0.978	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.978	0.022
E28.8 Other ovarian dysfunction	0.000	0.978	0.022
E28.1 Androgen excess	0.000	0.978	0.022
E28.0 Oestrogen excess	0.000	0.978	0.022
E22.0 Acromegaly and pituitary gigantism	0.000	0.978	0.022
E22.1 Hyperprolactinaemia	0.000	0.978	0.021
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.979	0.021
E22.8 Other hyperfunction of pituitary gland	0.000	0.979	0.021
E28.2 Polycystic ovarian syndrome	0.000	0.981	0.019
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.981	0.019
E28.3 Primary ovarian failure	0.000	0.982	0.018
B34.4 Papovirus infection, unspecified	0.018	0.982	0.000
B34.8 Other viral infections of unspecified site	0.018	0.982	0.000
B34.3 Parvovirus infection, unspecified	0.016	0.984	0.000
B34.2 Coronavirus infection, unspecified	0.016	0.984	0.000
B34.1 Enterovirus infection, unspecified	0.016	0.984	0.000
B34.0 Adenovirus infection, unspecified	0.016	0.984	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.984	0.015
E21.4 Other specified disorders of parathyroid gland	0.000	0.986	0.014
I08.0 Disorders of both mitral and aortic valves	0.014	0.986	0.000
Z88.2 Personal history of allergy to sulphonamides	0.013	0.987	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.987	0.013
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.988	0.012
E21.2 Other hyperparathyroidism	0.000	0.988	0.012
I08.8 Other multiple valve diseases	0.012	0.988	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.012	0.988	0.000
I08 Multiple valve diseases	0.011	0.989	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.011	0.989	0.000
N89.5 Stricture and atresia of vagina	0.000	0.989	0.011
C67.1 Dome of bladder	0.011	0.989	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.989	0.011
C67.9 Bladder, unspecified	0.011	0.989	0.000
X23.9 Unspecified place	0.010	0.990	0.000
C67.3 Anterior wall of bladder	0.010	0.990	0.000
C67 Malignant neoplasm of bladder	0.010	0.990	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.010	0.990	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.010	0.990	0.000
E21.0 Primary hyperparathyroidism	0.000	0.990	0.009
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.009	0.990	0.000
C67.0 Trigone of bladder	0.009	0.991	0.000
I05-I09 Chronic rheumatic heart diseases	0.009	0.991	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.009	0.991	0.000
I08.9 Multiple valve disease, unspecified	0.009	0.991	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.991	0.009
T46.1 Calcium-channel blockers	0.009	0.991	0.000
Chapter IX Diseases of the circulatory system	0.008	0.992	0.000
B25-B34 Other viral diseases	0.008	0.992	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.992	0.000
T46.7 Peripheral vasodilators	0.008	0.992	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.008	0.992	0.000
C67.5 Bladder neck	0.008	0.992	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.008	0.992	0.000
I42.0 Dilated cardiomyopathy	0.008	0.992	0.000
C67.7 Urachus	0.007	0.992	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.008	0.992	0.000
K26.7 Chronic without haemorrhage or perforation	0.007	0.993	0.000
I06 Rheumatic aortic valve diseases	0.007	0.993	0.000
I09 Other rheumatic heart diseases	0.007	0.993	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.007	0.993	0.000
I05 Rheumatic mitral valve diseases	0.007	0.993	0.000
X23 Contact with hornets, wasps and bees	0.007	0.993	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.993	0.007
I42.9 Cardiomyopathy, unspecified	0.006	0.994	0.000
C67.2 Lateral wall of bladder	0.006	0.994	0.000
B33 Other viral diseases, not elsewhere classified	0.006	0.994	0.000
R17 Unspecified jaundice	0.006	0.994	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.006	0.994	0.000
B30 Viral conjunctivitis	0.006	0.994	0.000
B26 Mumps	0.006	0.994	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.006	0.994	0.000
I05.1 Rheumatic mitral insufficiency	0.006	0.994	0.000
I99 Other and unspecified disorders of circulatory system	0.006	0.994	0.000
B27 Infectious mononucleosis	0.006	0.994	0.000
C67.8 Overlapping lesion of bladder	0.006	0.994	0.000
I05.0 Mitral stenosis	0.006	0.994	0.000
N80.8 Other endometriosis	0.000	0.994	0.006
I00-I02 Acute rheumatic fever	0.006	0.994	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.005	0.994	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.006	0.994	0.000
X23.0 Home	0.005	0.994	0.000
B25 Cytomegaloviral disease	0.005	0.994	0.000
I42 Cardiomyopathy	0.006	0.994	0.000
I09.9 Rheumatic heart disease, unspecified	0.005	0.995	0.000
D86.0 Sarcoidosis of lung	0.000	0.995	0.005
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.995	0.005
I06.8 Other rheumatic aortic valve diseases	0.005	0.995	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.005	0.995	0.000
I06.1 Rheumatic aortic insufficiency	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.005	0.995	0.000
I09.2 Chronic rheumatic pericarditis	0.005	0.995	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.005	0.995	0.000
I09.0 Rheumatic myocarditis	0.005	0.995	0.000
C67.4 Posterior wall of bladder	0.005	0.995	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.005	0.995	0.000
I06.0 Rheumatic aortic stenosis	0.005	0.995	0.000
I05.8 Other mitral valve diseases	0.005	0.995	0.000
X23.8 Other specified place	0.005	0.995	0.000
X23.7 Farm	0.005	0.995	0.000
X23.6 Industrial and construction area	0.005	0.995	0.000
X23.5 Trade and service area	0.005	0.995	0.000
X23.4 Street and highway	0.005	0.995	0.000
X23.3 Sports and athletics area	0.005	0.995	0.000
X23.2 School, other institution and public administrative area	0.005	0.995	0.000
X23.1 Residential institution	0.005	0.995	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.005	0.995	0.000
B33.2 Viral carditis	0.005	0.995	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.005	0.995	0.000
B33.8 Other specified viral diseases	0.004	0.995	0.000
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.004	0.995	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.004	0.995	0.000
B33.1 Ross River disease	0.004	0.995	0.000
B33.0 Epidemic myalgia	0.004	0.995	0.000
I42.6 Alcoholic cardiomyopathy	0.005	0.995	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.005	0.995	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I98.0 Cardiovascular syphilis	0.005	0.995	0.000
K52 Other non-infective gastro-enteritis and colitis	0.005	0.995	0.000
B26.9 Mumps without complication	0.004	0.995	0.000
B26.8 Mumps with other complications	0.004	0.995	0.000
B26.3 Mumps pancreatitis	0.004	0.995	0.000
B26.2 Mumps encephalitis	0.004	0.995	0.000
B26.1 Mumps meningitis	0.004	0.995	0.000
B26.0 Mumps orchitis	0.004	0.995	0.000
B30.9 Viral conjunctivitis, unspecified	0.004	0.995	0.000
B30.8 Other viral conjunctivitis	0.004	0.995	0.000
B30.3 Acute epidemic haemorrhagic conjunctivitis (enteroviral)	0.004	0.995	0.000
B30.2 Viral pharyngoconjunctivitis	0.004	0.995	0.000
B30.1 Conjunctivitis due to adenovirus	0.004	0.995	0.000
B30.0 Keratoconjunctivitis due to adenovirus	0.004	0.995	0.000
I42.5 Other restrictive cardiomyopathy	0.005	0.995	0.000
B27.8 Other infectious mononucleosis	0.004	0.995	0.000
B27.1 Cytomegaloviral mononucleosis	0.004	0.995	0.000
B27.0 Gammaherpesviral mononucleosis	0.004	0.995	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.005	0.995	0.000
Z39.1 Care and examination of lactating mother	0.004	0.995	0.000
L50.9 Urticaria, unspecified	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.004	0.996	0.000
I02 Rheumatic chorea	0.004	0.996	0.000
I01 Rheumatic fever with heart involvement	0.004	0.996	0.000
B27.9 Infectious mononucleosis, unspecified	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
B25.2 Cytomegaloviral pancreatitis	0.004	0.996	0.000
B25.1 Cytomegaloviral hepatitis	0.004	0.996	0.000
B25.0 Cytomegaloviral pneumonitis	0.004	0.996	0.000
I05.2 Mitral stenosis with insufficiency	0.004	0.996	0.000
I42.4 Endocardial fibroelastosis	0.004	0.996	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.004	0.996	0.000
C67.6 Ureteric orifice	0.004	0.996	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.996	0.004
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
B25.9 Cytomegaloviral disease, unspecified	0.004	0.996	0.000
I95.2 Hypotension due to drugs	0.004	0.996	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.004	0.996	0.000
I97.0 Postcardiotomy syndrome	0.004	0.996	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.004	0.996	0.000
I00 Rheumatic fever without mention of heart involvement	0.004	0.996	0.000
C64-C68 Malignant neoplasms of urinary tract	0.004	0.996	0.000
I95 Hypotension	0.004	0.996	0.000
B25.8 Other cytomegaloviral diseases	0.004	0.996	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
S71.1 Open wound of thigh	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.996	0.000
I33.0 Acute and subacute infective endocarditis	0.004	0.996	0.000
L50 Urticaria	0.003	0.997	0.000
I33 Acute and subacute endocarditis	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.003	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.003	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.003	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.003	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.003	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.003	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.003	0.997	0.000
I30-I52 Other forms of heart disease	0.003	0.997	0.000
C50.0 Nipple and areola	0.003	0.997	0.000
I95.8 Other hypotension	0.003	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.003	0.997	0.000
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
I95.0 Idiopathic hypotension	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.003	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.003	0.997	0.000
L50.1 Idiopathic urticaria	0.003	0.997	0.000
L50.0 Allergic urticaria	0.003	0.997	0.000
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
I30 Acute pericarditis	0.003	0.997	0.000
Z87.8 Personal history of other specified conditions	0.003	0.997	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.003	0.997	0.000
K52.1 Toxic gastro-enteritis and colitis	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.003	0.997	0.000
H10 Conjunctivitis	0.000	0.997	0.003
K52.3 Indeterminate colitis	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
I33.9 Acute endocarditis, unspecified	0.003	0.997	0.000
I47 Paroxysmal tachycardia	0.003	0.997	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
C68.0 Urethra	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
L50.8 Other urticaria	0.003	0.997	0.000
X20-X29 Contact with venomous animals and plants	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
L50.6 Contact urticaria	0.003	0.997	0.000
L50.5 Cholinergic urticaria	0.003	0.997	0.000
L50.4 Vibratory urticaria	0.003	0.997	0.000
L50.3 Dermatographic urticaria	0.003	0.997	0.000
L50.2 Urticaria due to cold and heat	0.003	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
R09.0 Asphyxia	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.003	0.997	0.000
I48 Atrial fibrillation and flutter	0.003	0.997	0.000
I41 Myocarditis in diseases classified elsewhere	0.003	0.997	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I32 Pericarditis in diseases classified elsewhere	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
I37 Pulmonary valve disorders	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
C68.9 Urinary organ, unspecified	0.002	0.997	0.000
C68.8 Overlapping lesion of urinary organs	0.002	0.997	0.000
C68.1 Paraurethral glands	0.002	0.997	0.000
I35.9 Aortic valve disorder, unspecified	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
I40 Acute myocarditis	0.002	0.997	0.000
I46 Cardiac arrest	0.003	0.997	0.000
I38 Endocarditis, valve unspecified	0.003	0.997	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.003
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.997	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
H10.4 Chronic conjunctivitis	0.000	0.997	0.002
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.997	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.997	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.997	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
I30.8 Other forms of acute pericarditis	0.002	0.997	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.002	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.000	0.998	0.002
H10.8 Other conjunctivitis	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H10.2 Other acute conjunctivitis	0.000	0.998	0.002
H10.1 Acute atopic conjunctivitis	0.000	0.998	0.002
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.998	0.002
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
X29 Contact with unspecified venomous animal or plant	0.002	0.998	0.000
X28 Contact with other specified venomous plants	0.002	0.998	0.000
X27 Contact with other specified venomous animals	0.002	0.998	0.000
X26 Contact with venomous marine animals and plants	0.002	0.998	0.000
X25 Contact with other specified venomous arthropods	0.002	0.998	0.000
X24 Contact with centipedes and venomous millipedes (tropical)	0.002	0.998	0.000
X22 Contact with scorpions	0.002	0.998	0.000
X21 Contact with venomous spiders	0.002	0.998	0.000
X20 Contact with venomous snakes and lizards	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T36.3 Macrolides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.002	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I35.8 Other aortic valve disorders	0.002	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.002	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.002	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.002	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.002	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.002	0.998	0.000
I48.4 Atypical atrial flutter	0.002	0.998	0.000
I48.3 Typical atrial flutter	0.002	0.998	0.000
I48.2 Chronic atrial fibrillation	0.002	0.998	0.000
I48.1 Persistent atrial fibrillation	0.002	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations