TreeWAS – Variant ID: rs1902859

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	1.000	0.000	0.000
I10-I15 Hypertensive diseases	0.178	0.822	0.000
I13 Hypertensive heart and renal disease	0.142	0.858	0.000
I15 Secondary hypertension	0.112	0.888	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.111	0.889	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.109	0.890	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.102	0.898	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.102	0.898	0.000
I11 Hypertensive heart disease	0.089	0.911	0.000
I15.8 Other secondary hypertension	0.088	0.911	0.000
I15.1 Hypertension secondary to other renal disorders	0.084	0.916	0.000
I15.2 Hypertension secondary to endocrine disorders	0.081	0.919	0.000
I12 Hypertensive renal disease	0.077	0.923	0.000
I15.0 Renovascular hypertension	0.075	0.924	0.000
I12.9 Hypertensive renal disease without renal failure	0.055	0.945	0.000
I15.9 Seconday hypertension, unspecified	0.053	0.947	0.001
I11.0 Hypertensive heart disease with (congestive) heart failure	0.053	0.947	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.044	0.956	0.000
I44.7 Left bundle-branch block, unspecified	0.024	0.976	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.984	0.016
I25.1 Atherosclerotic heart disease	0.014	0.986	0.000
D12.4 Descending colon	0.000	0.986	0.014
I25.8 Other forms of chronic ischaemic heart disease	0.013	0.987	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.989	0.011
I44 Atrioventricular and left bundle-branch block	0.011	0.989	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.990	0.010
I25 Chronic ischaemic heart disease	0.010	0.990	0.000
I44.2 Atrioventricular block, complete	0.010	0.990	0.000
R25.2 Cramp and spasm	0.000	0.990	0.010
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.990	0.010
N18.3 Chronic kidney disease, stage 3	0.000	0.991	0.009
F10.1 Harmful use	0.009	0.991	0.000
I44.3 Other and unspecified atrioventricular block	0.009	0.991	0.000
I44.4 Left anterior fascicular block	0.008	0.992	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.008	0.992	0.000
I44.1 Atrioventricular block, second degree	0.008	0.992	0.000
N18 Chronic renal failure	0.000	0.992	0.008
I44.5 Left posterior fascicular block	0.008	0.992	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.992	0.008
M07.39 Other psoriatic arthropathies (Site unspecified)	0.008	0.992	0.000
I25.6 Silent myocardial ischaemia	0.007	0.993	0.000
I25.4 Coronary artery aneurysm	0.007	0.993	0.000
M07.3 Other psoriatic arthropathies	0.007	0.993	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.007	0.993	0.000
N18.0 End-stage renal disease	0.000	0.994	0.006
N18.5 Chronic kidney disease, stage 5	0.000	0.994	0.006
M07.36 Other psoriatic arthropathies (Lower leg)	0.006	0.994	0.000
I24.8 Other forms of acute ischaemic heart disease	0.006	0.994	0.000
N18.1 Chronic kidney disease, stage 1	0.000	0.994	0.006
M07.31 Other psoriatic arthropathies (Shoulder region)	0.006	0.994	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.006	0.994	0.000
I24 Other acute ischaemic heart diseases	0.006	0.994	0.000
I20-I25 Ischaemic heart diseases	0.006	0.994	0.000
N18.8 Other chronic renal failure	0.000	0.995	0.005
M07.38 Other psoriatic arthropathies (Other)	0.005	0.995	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.005	0.995	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.005	0.995	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.005	0.995	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.005	0.995	0.000
H50.0 Convergent concomitant strabismus	0.000	0.995	0.005
T58 Toxic effect of carbon monoxide	0.005	0.995	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.005	0.995	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.995	0.005
I25.5 Ischaemic cardiomyopathy	0.005	0.995	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.005	0.995	0.000
I44.6 Other and unspecified fascicular block	0.005	0.995	0.000
I23 Certain current complications following acute myocardial infarction	0.005	0.995	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.995	0.005
I21 Acute myocardial infarction	0.005	0.995	0.000
N17 Acute renal failure	0.000	0.995	0.005
R25 Abnormal involuntary movements	0.000	0.995	0.005
I24.1 Dressler's syndrome	0.004	0.995	0.000
I51.9 Heart disease, unspecified	0.004	0.996	0.000
I25.3 Aneurysm of heart	0.004	0.996	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.004	0.996	0.000
N17.9 Acute renal failure, unspecified	0.000	0.996	0.004
I21.2 Acute transmural myocardial infarction of other sites	0.004	0.996	0.000
I23.8 Other current complications following acute myocardial infarction	0.004	0.996	0.000
N17-N19 Renal failure	0.000	0.996	0.004
S90.8 Other superficial injuries of ankle and foot	0.000	0.996	0.004
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.004	0.996	0.000
R25.1 Tremor, unspecified	0.000	0.996	0.004
S82.30 Fracture of lower end of tibia (closed)	0.004	0.996	0.000
I21.4 Acute subendocardial myocardial infarction	0.004	0.996	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.004	0.996	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.004	0.996	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.004	0.996	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.996	0.004
I21.X Presumed acute myicardial infaction (unconfirmed)	0.004	0.996	0.000
N17.2 Acute renal failure with medullary necrosis	0.000	0.996	0.003
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.996	0.003
R25.0 Abnormal head movements	0.000	0.996	0.003
R25.3 Fasciculation	0.000	0.996	0.003
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.996	0.004
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.996	0.004
M87.2 Osteonecrosis due to previous trauma	0.003	0.996	0.000
N17.8 Other acute renal failure	0.000	0.997	0.003
N30.2 Other chronic cystitis	0.000	0.997	0.003
I21.3 Acute transmural myocardial infarction of unspecified site	0.003	0.997	0.000
N76.0 Acute vaginitis	0.000	0.997	0.003
M07 Psoriatic and enteropathic arthropathies	0.003	0.997	0.000
I45.3 Trifascicular block	0.003	0.997	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
Chapter IX Diseases of the circulatory system	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
O42.9 Premature rupture of membranes, unspecified	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.000	0.997	0.003
T59.8 Other specified gases, fumes and vapours	0.003	0.997	0.000
M87 Osteonecrosis	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.003	0.997	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.997	0.003
T59 Toxic effect of other gases, fumes and vapours	0.003	0.997	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.003	0.997	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.003	0.997	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.003	0.997	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.003	0.997	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.003	0.997	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.003	0.997	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.003	0.997	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.003	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
I45.2 Bifascicular block	0.003	0.997	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.000	0.997	0.003
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
M87.8 Other osteonecrosis	0.002	0.997	0.000
I45 Other conduction disorders	0.003	0.997	0.000
M07.6 Other enteropathic arthropathies	0.002	0.997	0.000
M07.5 Arthropathy in ulcerative colitis	0.002	0.997	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.997	0.000
M07.2 Psoriatic spondylitis	0.002	0.997	0.000
M07.1 Arthritis mutilans	0.002	0.997	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.997	0.000
T63 Toxic effect of contact with venomous animals	0.002	0.997	0.000
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
L98.0 Pyogenic granuloma	0.003	0.997	0.000
I45.4 Nonspecific intraventricular block	0.002	0.998	0.000
T63.4 Venom of other arthropods	0.002	0.998	0.000
Z01.9 Special examination, unspecified	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.002	0.998	0.000
I37.1 Pulmonary valve insufficiency	0.002	0.998	0.000
L94.0 Localised scleroderma [morphea]	0.002	0.998	0.000
M87.3 Other secondary osteonecrosis	0.002	0.998	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.002	0.998	0.000
I37 Pulmonary valve disorders	0.002	0.998	0.000
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
I30-I52 Other forms of heart disease	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
T59.9 Gases, fumes and vapours, unspecified	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.998	0.002
T65 Toxic effect of other and unspecified substances	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
T59.7 Carbon dioxide	0.002	0.998	0.000
T59.6 Hydrogen sulphide	0.002	0.998	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.002	0.998	0.000
T59.4 Chlorine gas	0.002	0.998	0.000
T59.3 Lachrymogenic gas	0.002	0.998	0.000
T59.2 Formaldehyde	0.002	0.998	0.000
T59.1 Sulphur dioxide	0.002	0.998	0.000
T59.0 Nitrogen oxides	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
I45.0 Right fascicular block	0.002	0.998	0.000
M77.1 Lateral epicondylitis	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
S73.0 Dislocation of hip	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.002	0.998	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.002	0.998	0.000
T60 Toxic effect of pesticides	0.002	0.998	0.000
T57 Toxic effect of other inorganic substances	0.002	0.998	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.002	0.998	0.000
T52 Toxic effect of organic solvents	0.002	0.998	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.002	0.998	0.000
T55 Toxic effect of soaps and detergents	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.002	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.002	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.002	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
I40 Acute myocarditis	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.002	0.998	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.002	0.998	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.002	0.998	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.002	0.998	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.002	0.998	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.002	0.998	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.002	0.998	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.002	0.998	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.002	0.998	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.002	0.998	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.002	0.998	0.000
M07.18 Arthritis mutilans (Other)	0.002	0.998	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.002	0.998	0.000
M07.16 Arthritis mutilans (Lower leg)	0.002	0.998	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.002	0.998	0.000
M07.14 Arthritis mutilans (Hand)	0.002	0.998	0.000
M07.13 Arthritis mutilans (Forearm)	0.002	0.998	0.000
M07.12 Arthritis mutilans (Upper arm)	0.002	0.998	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.002	0.998	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.002	0.998	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.002	0.998	0.000
M07.28 Psoriatic spondylitis (Other)	0.002	0.998	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.002	0.998	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.002	0.998	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.002	0.998	0.000
M07.24 Psoriatic spondylitis (Hand)	0.002	0.998	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.002	0.998	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.002	0.998	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.002	0.998	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.002	0.998	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.002	0.998	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.002	0.998	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.002	0.998	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.002	0.998	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.002	0.998	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.002	0.998	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.002	0.998	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.002	0.998	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.002	0.998	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.002	0.998	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.002	0.998	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.002	0.998	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.002	0.998	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.002	0.998	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.002	0.998	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.002	0.998	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.002	0.998	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.002	0.998	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.002	0.998	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.002	0.998	0.000
M07.68 Other enteropathic arthropathies (Other)	0.002	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.002	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.002	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.002	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.002	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.002	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.002	0.998	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.002	0.998	0.000
T63.8 Toxic effect of contact with other venomous animals	0.002	0.998	0.000
T63.6 Toxic effect of contact with other marine animals	0.002	0.998	0.000
T63.5 Toxic effect of contact with fish	0.002	0.998	0.000
T63.3 Venom of spider	0.002	0.998	0.000
T63.2 Venom of scorpion	0.002	0.998	0.000
T63.1 Venom of other reptiles	0.002	0.998	0.000
T63.0 Snake venom	0.002	0.998	0.000
T65.9 Toxic effect of unspecified substance	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
T62 Toxic effect of other noxious substances eaten as food	0.002	0.998	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
T56 Toxic effect of metals	0.002	0.998	0.000
K07.3 Anomalies of tooth position	0.000	0.998	0.002
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
I30.1 Infective pericarditis	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
I37.0 Pulmonary valve stenosis	0.002	0.998	0.000
X58.9 Unspecified place	0.002	0.998	0.000
Z01.7 Laboratory examination	0.000	0.998	0.002
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.002	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.002	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.002	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.002	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.002	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.002	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.002	0.998	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.002	0.998	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.002	0.998	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.002	0.998	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.38 Other secondary osteonecrosis (Other)	0.002	0.998	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.002	0.998	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.002	0.998	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.002	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
I37.9 Pulmonary valve disorder, unspecified	0.002	0.998	0.000
I37.8 Other pulmonary valve disorders	0.002	0.998	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.002	0.998	0.000
I02 Rheumatic chorea	0.002	0.998	0.000
I01 Rheumatic fever with heart involvement	0.002	0.998	0.000
T54 Toxic effect of corrosive substances	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.002	0.998	0.000
I48 Atrial fibrillation and flutter	0.002	0.998	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.002	0.998	0.000
I41 Myocarditis in diseases classified elsewhere	0.002	0.998	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I32 Pericarditis in diseases classified elsewhere	0.002	0.998	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
I40.0 Infective myocarditis	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
T65.8 Toxic effect of other specified substances	0.002	0.998	0.000
T65.6 Paints and dyes, not elsewhere classified	0.002	0.998	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.002	0.998	0.000
T65.4 Carbon disulphide	0.002	0.998	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.002	0.998	0.000
T65.2 Tobacco and nicotine	0.002	0.998	0.000
T65.1 Strychnine and its salts	0.002	0.998	0.000
T65.0 Cyanides	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.998	0.002
M77.18 Lateral epicondylitis-Other	0.000	0.998	0.002
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.998	0.002
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.998	0.002
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.998	0.002
M77.14 Lateral epicondylitis-Hand	0.000	0.998	0.002
M77.11 Lateral epicondylitis-Shldr region	0.000	0.998	0.002
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
I45.9 Conduction disorder, unspecified	0.002	0.998	0.000
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998	0.000
I31 Other diseases of pericardium	0.002	0.998	0.000
M77.13 Lateral epicondylitis-Forearm	0.000	0.998	0.002
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
I40.9 Acute myocarditis, unspecified	0.002	0.998	0.000
T52.9 Organic solvent, unspecified	0.002	0.998	0.000
T52.8 Other organic solvents	0.002	0.998	0.000
T52.4 Ketones	0.002	0.998	0.000
T52.3 Glycols	0.002	0.998	0.000
T52.2 Homologues of benzene	0.002	0.998	0.000
T52.1 Benzene	0.002	0.998	0.000
T52.0 Petroleum products	0.002	0.998	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.002	0.998	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.002	0.998	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.002	0.998	0.000
T53.5 Chlorofluorocarbons	0.002	0.998	0.000
T53.4 Dichloromethane	0.002	0.998	0.000
T53.3 Tetrachloroethylene	0.002	0.998	0.000
T53.2 Trichloroethylene	0.002	0.998	0.000
T53.1 Chloroform	0.002	0.998	0.000
T53.0 Carbon tetrachloride	0.002	0.998	0.000
T57.9 Inorganic substance, unspecified	0.002	0.998	0.000
T57.8 Other specified inorganic substances	0.002	0.998	0.000
T57.3 Hydrogen cyanide	0.002	0.998	0.000
T57.2 Manganese and its compounds	0.002	0.998	0.000
T57.1 Phosphorus and its compounds	0.002	0.998	0.000
T57.0 Arsenic and its compounds	0.002	0.998	0.000
T60.9 Pesticide, unspecified	0.002	0.998	0.000
T60.8 Other pesticides	0.002	0.998	0.000
T60.4 Rodenticides	0.002	0.998	0.000
T60.3 Herbicides and fungicides	0.002	0.998	0.000
T60.2 Other insecticides	0.002	0.998	0.000
T60.1 Halogenated insecticides	0.002	0.998	0.000
T60.0 Organophosphate and carbamate insecticides	0.002	0.998	0.000
T61.9 Toxic effect of unspecified seafood	0.002	0.998	0.000
T61.8 Toxic effect of other seafoods	0.002	0.998	0.000
T61.2 Other fish and shellfish poisoning	0.002	0.998	0.000
T61.1 Scombroid fish poisoning	0.002	0.998	0.000
T61.0 Ciguatera fish poisoning	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.998	0.002
S70.1 Contusion of thigh	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.002	0.998	0.000
C91.0 Acute lymphoblastic leukaemia	0.002	0.998	0.000
I40.8 Other acute myocarditis	0.002	0.998	0.000
I40.1 Isolated myocarditis	0.002	0.998	0.000
S73.1 Sprain and strain of hip	0.002	0.998	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.002	0.998	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.002	0.998	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.002	0.998	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
T62.8 Other specified noxious substances eaten as food	0.002	0.998	0.000
T62.2 Other ingested (parts of) plant(s)	0.002	0.998	0.000
T62.1 Ingested berries	0.002	0.998	0.000
T62.0 Ingested mushrooms	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
T56.9 Metal, unspecified	0.002	0.998	0.000
T56.7 Beryllium and its compounds	0.002	0.998	0.000
T56.6 Tin and its compounds	0.002	0.998	0.000
T56.5 Zinc and its compounds	0.002	0.998	0.000
T56.4 Copper and its compounds	0.002	0.998	0.000
T56.3 Cadmium and its compounds	0.002	0.998	0.000
T56.2 Chromium and its compounds	0.002	0.998	0.000
T56.1 Mercury and its compounds	0.002	0.998	0.000
T56.0 Lead and its compounds	0.002	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
C48.1 Specified parts of peritoneum	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.998	0.002
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.001	0.998	0.000
I01.8 Other acute rheumatic heart disease	0.001	0.998	0.000
I01.2 Acute rheumatic myocarditis	0.001	0.998	0.000
I01.1 Acute rheumatic endocarditis	0.001	0.998	0.000
I01.0 Acute rheumatic pericarditis	0.001	0.998	0.000
I02.9 Rheumatic chorea without heart involvement	0.001	0.998	0.000
I02.0 Rheumatic chorea with heart involvement	0.001	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
T54.3 Corrosive alkalis and alklali-like substances	0.001	0.998	0.000
T54.2 Corrosive acids and acid-like substances	0.001	0.998	0.000
T54.1 Other corrosive organic compounds	0.001	0.998	0.000
T54.0 Phenol and phenol homologues	0.001	0.998	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.001	0.998	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.001	0.998	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.001	0.998	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.001	0.998	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.001	0.998	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.001	0.998	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.001	0.998	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.001	0.998	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.001	0.998	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.001	0.998	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.001	0.998	0.000
I48.4 Atypical atrial flutter	0.001	0.998	0.000
I48.3 Typical atrial flutter	0.001	0.998	0.000
I48.2 Chronic atrial fibrillation	0.001	0.998	0.000
I48.1 Persistent atrial fibrillation	0.001	0.998	0.000
I48.0 Paroxysmal atrial fibrillation	0.001	0.998	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.001	0.998	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.001	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations