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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs191953093
log Bayes Factor = 2.3996
Chromosome 1   position 181,006,881  (GRCh37) Explore rs191953093 on Ensembl!
Variant rs191953093 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.979 0.021 0.000
Chapter XIV Diseases of the genitourinary system
0.969 0.031 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.965 0.035 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.949 0.051 0.000
Chapter VII Diseases of the eye and adnexa
0.942 0.058 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.926 0.074 0.000
Chapter II Neoplasms
0.919 0.081 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.911 0.089 0.000
Chapter IX Diseases of the circulatory system
0.905 0.095 0.000
Z85 Personal history of malignant neoplasm
0.890 0.110 0.000
Chapter XX External causes of morbidity and mortality
0.874 0.126 0.000
H25-H28 Disorders of lens
0.872 0.128 0.000
Z13 Special screening examination for other diseases and disorders
0.864 0.136 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.859 0.141 0.000
R00 Abnormalities of heart beat
0.857 0.143 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.850 0.150 0.000
Chapter XI Diseases of the digestive system
0.834 0.166 0.000
N30-N39 Other diseases of urinary system
0.834 0.166 0.000
R07 Pain in throat and chest
0.825 0.175 0.000
Z92 Personal history of medical treatment
0.825 0.175 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.813 0.187 0.000
R06 Abnormalities of breathing
0.807 0.193 0.000
H26 Other cataract
0.803 0.197 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.797 0.203 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.793 0.207 0.000
R00.2 Palpitations
0.792 0.208 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.792 0.208 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.792 0.208 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.790 0.210 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.787 0.213 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.781 0.219 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.779 0.221 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.774 0.226 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.773 0.227 0.000
N40-N51 Diseases of male genital organs
0.771 0.229 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.770 0.230 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.764 0.236 0.000
R07.3 Other chest pain
0.761 0.239 0.000
N35 Urethral stricture
0.760 0.240 0.000
I10-I15 Hypertensive diseases
0.758 0.242 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.758 0.242 0.000
N20-N23 Urolithiasis
0.756 0.244 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.756 0.244 0.000
H30-H36 Disorders of choroid and retina
0.755 0.245 0.000
H26.9 Cataract, unspecified
0.753 0.247 0.000
Z13.9 Special screening examination, unspecified
0.753 0.247 0.000
I30-I52 Other forms of heart disease
0.752 0.248 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.752 0.248 0.000
I20-I25 Ischaemic heart diseases
0.751 0.249 0.000
R04 Haemorrhage from respiratory passages
0.747 0.253 0.000
Chapter X Diseases of the respiratory system
0.738 0.262 0.000
N25-N29 Other disorders of kidney and ureter
0.738 0.262 0.000
C64-C68 Malignant neoplasms of urinary tract
0.736 0.264 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.733 0.266 0.000
K29 Gastritis and duodenitis
0.732 0.268 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.731 0.269 0.000
N60-N64 Disorders of breast
0.730 0.270 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.730 0.270 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.730 0.270 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.728 0.272 0.000
H40-H42 Glaucoma
0.721 0.279 0.000
N92 Excessive, frequent and irregular menstruation
0.719 0.281 0.000
N17-N19 Renal failure
0.718 0.282 0.000
N84 Polyp of female genital tract
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.714 0.286 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.714 0.286 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.713 0.287 0.000
Z80 Family history of malignant neoplasm
0.711 0.289 0.000
N35.9 Urethral stricture, unspecified
0.707 0.293 0.000
R50-R69 General symptoms and signs
0.705 0.295 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.703 0.296 0.000
R05 Cough
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.702 0.298 0.000
Chapter I Certain infectious and parasitic diseases
0.700 0.300 0.000
K50-K52 Noninfective enteritis and colitis
0.699 0.301 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.699 0.301 0.000
Z12 Special screening examination for neoplasms
0.698 0.302 0.000
H25 Senile cataract
0.696 0.304 0.000
N99-N99 Other disorders of the genitourinary system
0.695 0.305 0.000
N10-N16 Renal tubulo-interstitial diseases
0.695 0.305 0.000
N00-N08 Glomerular diseases
0.695 0.305 0.000
N89 Other noninflammatory disorders of vagina
0.693 0.307 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.693 0.307 0.000
R07.2 Precordial pain
0.693 0.307 0.000
Chapter VIII Diseases of the ear and mastoid process
0.692 0.307 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.692 0.308 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.692 0.308 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.692 0.308 0.000
R47-R49 Symptoms and signs involving speech and voice
0.692 0.308 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.691 0.309 0.000
C15-C26 Malignant neoplasms of digestive organs
0.689 0.311 0.000
K31 Other diseases of stomach and duodenum
0.686 0.314 0.000
Z02 Examination and encounter for administrative purposes
0.684 0.316 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.684 0.316 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.682 0.317 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.680 0.319 0.000
R01 Cardiac murmurs and other cardiac sounds
0.680 0.319 0.000
R02 Gangrene, not elsewhere classified
0.680 0.319 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.679 0.321 0.000
Z47 Other orthopaedic follow-up care
0.679 0.321 0.000
W00-W19 Falls
0.679 0.321 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.677 0.323 0.000
C50-C50 Malignant neoplasm of breast
0.676 0.324 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.675 0.325 0.000
H55-H59 Other disorders of eye and adnexa
0.675 0.325 0.000
H53-H54 Visual disturbances and blindness
0.675 0.325 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.675 0.325 0.000
H43-H45 Disorders of vitreous body and globe
0.675 0.325 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.675 0.325 0.000
H10-H13 Disorders of conjunctiva
0.675 0.325 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.672 0.328 0.000
Y95 Nosocomial condition
0.672 0.328 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.667 0.333 0.000
N86 Erosion and ectropion of cervix uteri
0.666 0.333 0.000
D10-D36 Benign neoplasms
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.665 0.335 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.665 0.335 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.664 0.336 0.000
Z97 Presence of other devices
0.664 0.336 0.000
Z94 Transplanted organ and tissue status
0.664 0.336 0.000
Z93 Artificial opening status
0.664 0.336 0.000
Z89 Acquired absence of limb
0.664 0.336 0.000
Z84 Family history of other conditions
0.664 0.336 0.000
Z83 Family history of other specific disorders
0.664 0.336 0.000
Z81 Family history of mental and behavioural disorders
0.664 0.336 0.000
Z51 Other medical care
0.662 0.338 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.662 0.338 0.000
Z95.4 Presence of other heart-valve replacement
0.660 0.339 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.659 0.341 0.000
D00-D09 In situ neoplasms
0.659 0.341 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.659 0.341 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.659 0.341 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.659 0.341 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.659 0.341 0.000
C51-C58 Malignant neoplasms of female genital organs
0.659 0.341 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.659 0.341 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.659 0.341 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.659 0.341 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.657 0.343 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.657 0.343 0.000
C60-C63 Malignant neoplasms of male genital organs
0.654 0.346 0.000
I10 Essential (primary) hypertension
0.654 0.346 0.000
R69 Unknown and unspecified causes of morbidity
0.654 0.346 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.653 0.347 0.000
Z10 Routine general health check-up of defined subpopulation
0.653 0.347 0.000
Z04 Examination and observation for other reasons
0.653 0.347 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.653 0.347 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.653 0.347 0.000
I05-I09 Chronic rheumatic heart diseases
0.649 0.351 0.000
I00-I02 Acute rheumatic fever
0.649 0.351 0.000
Z98 Other postsurgical states
0.648 0.352 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.646 0.354 0.000
R06.8 Other and unspecified abnormalities of breathing
0.645 0.355 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.644 0.356 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.639 0.361 0.000
R21 Rash and other nonspecific skin eruption
0.639 0.361 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.638 0.362 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.638 0.362 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.638 0.362 0.000
Z85.6 Personal history of leukaemia
0.638 0.362 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.638 0.362 0.000
K31.7 Polyp of stomach and duodenum
0.638 0.362 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.636 0.364 0.000
R11 Nausea and vomiting
0.636 0.364 0.000
N93 Other abnormal uterine and vaginal bleeding
0.636 0.364 0.000
I49 Other cardiac arrhythmias
0.635 0.364 0.000
E70-E90 Metabolic disorders
0.635 0.365 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.633 0.367 0.000
L60-L75 Disorders of skin appendages
0.628 0.372 0.000
K70-K77 Diseases of liver
0.627 0.373 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.627 0.373 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.627 0.373 0.000
Y35-Y36 Legal intervention and operations of war
0.627 0.373 0.000
Y10-Y34 Event of undetermined intent
0.627 0.373 0.000
Y00-Y09 Assault
0.627 0.373 0.000
X85-X99 Assault
0.627 0.373 0.000
X60-X84 Intentional self-harm
0.627 0.373 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.627 0.373 0.000
X50-X57 Overexertion, travel and privation
0.627 0.373 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.627 0.373 0.000
X30-X39 Exposure to forces of nature
0.627 0.373 0.000
X20-X29 Contact with venomous animals and plants
0.627 0.373 0.000
X10-X19 Contact with heat and hot substances
0.627 0.373 0.000
X00-X09 Exposure to smoke, fire and flames
0.627 0.373 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.627 0.373 0.000
W75-W84 Other accidental threats to breathing
0.627 0.373 0.000
W65-W74 Accidental drowning and submersion
0.627 0.373 0.000
W50-W64 Exposure to animate mechanical forces
0.627 0.373 0.000
W20-W49 Exposure to inanimate mechanical forces
0.627 0.373 0.000
V98-V99 Other and unspecified transport accidents
0.627 0.373 0.000
V95-V97 Air and space transport accidents
0.627 0.373 0.000
V90-V94 Water transport accidents
0.627 0.373 0.000
V80-V89 Other land transport accidents
0.627 0.373 0.000
V70-V79 Bus occupant injured in transport accident
0.627 0.373 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.627 0.373 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.627 0.373 0.000
V40-V49 Car occupant injured in transport accident
0.627 0.373 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.627 0.373 0.000
V20-V29 Motorcycle rider injured in transport accident
0.627 0.373 0.000
V10-V19 Pedal cyclist injured in transport accident
0.627 0.373 0.000
V01-V09 Pedestrian injured in transport accident
0.627 0.373 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.625 0.374 0.000
H27 Other disorders of lens
0.625 0.374 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.626 0.374 0.000
R06.0 Dyspnoea
0.625 0.375 0.000
R06.5 Mouth breathing
0.625 0.375 0.000
S00-S09 Injuries to the head
0.625 0.375 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.624 0.376 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.624 0.376 0.000
Chapter VI Diseases of the nervous system
0.623 0.377 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.623 0.377 0.000
H35 Other retinal disorders
0.622 0.378 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.620 0.380 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.620 0.380 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.620 0.380 0.000
Z13.5 Special screening examination for eye and ear disorders
0.620 0.380 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.620 0.380 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.620 0.380 0.000
Z13.2 Special screening examination for nutritional disorders
0.620 0.380 0.000
Z13.1 Special screening examination for diabetes mellitus
0.620 0.380 0.000
E50-E64 Other nutritional deficiencies
0.617 0.383 0.000
N98 Complications associated with artificial fertilisation
0.616 0.384 0.000
N97 Female infertility
0.616 0.384 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.616 0.384 0.000
N91 Absent, scanty and rare menstruation
0.616 0.384 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.616 0.384 0.000
N88 Other noninflammatory disorders of cervix uteri
0.616 0.384 0.000
N87 Dysplasia of cervix uteri
0.616 0.384 0.000
N82 Fistulae involving female genital tract
0.616 0.384 0.000
N80 Endometriosis
0.616 0.384 0.000
N96 Habitual aborter
0.616 0.384 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.615 0.385 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.614 0.386 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.614 0.386 0.000
R00.1 Bradycardia, unspecified
0.614 0.386 0.000
K22 Other diseases of oesophagus
0.614 0.386 0.000
I20 Angina pectoris
0.613 0.387 0.000
K29.7 Gastritis, unspecified
0.611 0.389 0.000
I60-I69 Cerebrovascular diseases
0.610 0.390 0.000
K29.5 Chronic gastritis, unspecified
0.610 0.390 0.000
R03.1 Nonspecific low blood-pressure reading
0.610 0.390 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.609 0.391 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.609 0.391 0.000
Z95.3 Presence of xenogenic heart valve
0.609 0.391 0.000
Z95.2 Presence of prosthetic heart valve
0.609 0.391 0.000
Z95.0 Presence of cardiac pacemaker
0.609 0.391 0.000
R00.0 Tachycardia, unspecified
0.608 0.392 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.607 0.392 0.000
R15 Faecal incontinence
0.607 0.393 0.000
R17 Unspecified jaundice
0.607 0.393 0.000
I25 Chronic ischaemic heart disease
0.606 0.394 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.606 0.394 0.000
N84.0 Polyp of corpus uteri
0.606 0.394 0.000
C67 Malignant neoplasm of bladder
0.605 0.395 0.000
S80-S89 Injuries to the knee and lower leg
0.604 0.395 0.000
K52 Other non-infective gastro-enteritis and colitis
0.603 0.397 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.602 0.398 0.000
N39 Other disorders of urinary system
0.601 0.399 0.000
K29.6 Other gastritis
0.599 0.401 0.000
K35-K38 Diseases of appendix
0.598 0.402 0.000
N37 Urethral disorders in diseases classified elsewhere
0.598 0.402 0.000
N36 Other disorders of urethra
0.598 0.402 0.000
N34 Urethritis and urethral syndrome
0.598 0.402 0.000
N33 Bladder disorders in diseases classified elsewhere
0.598 0.402 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.598 0.402 0.000
N30 Cystitis
0.598 0.402 0.000
S60-S69 Injuries to the wrist and hand
0.596 0.404 0.000
R04.0 Epistaxis
0.596 0.404 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.596 0.404 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.595 0.405 0.000
K29.8 Duodenitis
0.595 0.405 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.595 0.405 0.000
R07.1 Chest pain on breathing
0.592 0.408 0.000
R07.0 Pain in throat
0.592 0.408 0.000
Z92.9 Personal history of medical treatment, unspecified
0.592 0.408 0.000
Z92.8 Personal history of other medical treatment
0.592 0.408 0.000
Z92.5 Personal history of rehabilitation measures
0.592 0.408 0.000
Z92.0 Personal history of contraception
0.592 0.408 0.000
J20-J22 Other acute lower respiratory infections
0.591 0.409 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.591 0.409 0.000
O80-O84 Delivery
0.591 0.409 0.000
N23 Unspecified renal colic
0.583 0.416 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.583 0.417 0.000
T79-T79 Certain early complications of trauma
0.583 0.417 0.000
T66-T78 Other and unspecified effects of external causes
0.583 0.417 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.583 0.417 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.583 0.417 0.000
T33-T35 Frostbite
0.583 0.417 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.583 0.417 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.583 0.417 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.583 0.417 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.583 0.417 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.583 0.417 0.000
T00-T07 Injuries involving multiple body regions
0.583 0.417 0.000
S90-S99 Injuries to the ankle and foot
0.583 0.417 0.000
S70-S79 Injuries to the hip and thigh
0.583 0.417 0.000
S40-S49 Injuries to the shoulder and upper arm
0.583 0.417 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.583 0.417 0.000
S20-S29 Injuries to the thorax
0.583 0.417 0.000
S10-S19 Injuries to the neck
0.583 0.417 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.582 0.418 0.000
S50-S59 Injuries to the elbow and forearm
0.582 0.418 0.000
Z96 Presence of other functional implants
0.582 0.418 0.000
R06.7 Sneezing
0.578 0.422 0.000
R06.6 Hiccough
0.578 0.422 0.000
R06.4 Hyperventilation
0.578 0.422 0.000
R06.3 Periodic breathing
0.578 0.422 0.000
R06.2 Wheezing
0.578 0.422 0.000
R06.1 Stridor
0.578 0.422 0.000
N43 Hydrocele and spermatocele
0.578 0.422 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.576 0.424 0.000
E10-E14 Diabetes mellitus
0.576 0.424 0.000
H26.8 Other specified cataract
0.576 0.424 0.000
H26.4 After-cataract
0.576 0.424 0.000
H26.3 Drug-induced cataract
0.576 0.424 0.000
H26.2 Complicated cataract
0.576 0.424 0.000
H26.1 Traumatic cataract
0.576 0.424 0.000
H26.0 Infantile, juvenile and presenile cataract
0.576 0.424 0.000
N95 Menopausal and other perimenopausal disorders
0.575 0.424 0.000
O60-O75 Complications of labour and delivery
0.575 0.425 0.000
C43 Malignant melanoma of skin
0.574 0.426 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.574 0.426 0.000
J95-J99 Other diseases of the respiratory system
0.573 0.427 0.000
Z51.5 Palliative care
0.573 0.427 0.000
K65-K67 Diseases of peritoneum
0.573 0.427 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.572 0.428 0.000
Z54 Convalescence
0.571 0.429 0.000
Z52 Donors of organs and tissues
0.571 0.429 0.000
Z49 Care involving dialysis
0.571 0.429 0.000
Z48 Other surgical follow-up care
0.571 0.429 0.000
Z45 Adjustment and management of implanted device
0.571 0.429 0.000
Z44 Fitting and adjustment of external prosthetic device
0.571 0.429 0.000
Z43 Attention to artificial openings
0.571 0.429 0.000
Z42 Follow-up care involving plastic surgery
0.571 0.429 0.000
Z41 Procedures for purposes other than remedying health state
0.571 0.429 0.000
Z40 Prophylactic surgery
0.571 0.429 0.000
R18 Ascites
0.570 0.430 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.568 0.432 0.000
O85-O92 Complications predominantly related to the puerperium
0.568 0.432 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.568 0.432 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.568 0.432 0.000
O00-O08 Pregnancy with abortive outcome
0.568 0.432 0.000
N20 Calculus of kidney and ureter
0.567 0.433 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.566 0.434 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.566 0.434 0.000
Z87 Personal history of other diseases and conditions
0.566 0.434 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.564 0.436 0.000
E40-E46 Malnutrition
0.564 0.436 0.000
E20-E35 Disorders of other endocrine glands
0.564 0.436 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.564 0.436 0.000
K26 Duodenal ulcer
0.564 0.436 0.000
H40 Glaucoma
0.563 0.436 0.000
Z46 Fitting and adjustment of other devices
0.562 0.437 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.560 0.440 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.560 0.440 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.560 0.440 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.560 0.440 0.000
Z82.3 Family history of stroke
0.560 0.440 0.000
Z82.2 Family history of deafness and hearing loss
0.560 0.440 0.000
Z82.1 Family history of blindness and visual loss
0.560 0.440 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.560 0.440 0.000
N63 Unspecified lump in breast
0.559 0.441 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.558 0.442 0.000
R14 Flatulence and related conditions
0.558 0.442 0.000
H25.0 Senile incipient cataract
0.558 0.442 0.000
Z95.1 Presence of aortocoronary bypass graft
0.556 0.444 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.556 0.444 0.000
K28 Gastrojejunal ulcer
0.555 0.445 0.000
K27 Peptic ulcer, site unspecified
0.555 0.445 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.555 0.445 0.000
L50-L54 Urticaria and erythema
0.554 0.446 0.000
L40-L45 Papulosquamous disorders
0.554 0.446 0.000
L20-L30 Dermatitis and eczema
0.554 0.446 0.000
L10-L14 Bullous disorders
0.554 0.446 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.553 0.447 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.553 0.447 0.000
N48 Other disorders of penis
0.553 0.447 0.000
N45 Orchitis and epididymitis
0.553 0.447 0.000
N42 Other disorders of prostate
0.553 0.447 0.000
N41 Inflammatory diseases of prostate
0.553 0.447 0.000
N46 Male infertility
0.553 0.447 0.000
N44 Torsion of testis
0.553 0.447 0.000
R23 Other skin changes
0.552 0.448 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.552 0.448 0.000
M20-M25 Other joint disorders
0.552 0.448 0.000
I49.9 Cardiac arrhythmia, unspecified
0.552 0.448 0.000
E65-E68 Obesity and other hyperalimentation
0.552 0.448 0.000
C44 Other malignant neoplasms of skin
0.550 0.449 0.000
C34 Malignant neoplasm of bronchus and lung
0.549 0.451 0.000
A30-A49 Other bacterial diseases
0.549 0.451 0.000
N17 Acute renal failure
0.549 0.451 0.000
R60 Oedema, not elsewhere classified
0.548 0.452 0.000
Z60 Problems related to social environment
0.548 0.452 0.000
K30 Dyspepsia
0.547 0.453 0.000
I50 Heart failure
0.546 0.454 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.545 0.454 0.000
N35.8 Other urethral stricture
0.545 0.455 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.545 0.455 0.000
N35.0 Posttraumatic urethral stricture
0.545 0.455 0.000
I15 Secondary hypertension
0.544 0.456 0.000
I13 Hypertensive heart and renal disease
0.544 0.456 0.000
I12 Hypertensive renal disease
0.544 0.456 0.000
I11 Hypertensive heart disease
0.544 0.456 0.000
C80 Malignant neoplasm without specification of site
0.543 0.457 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.543 0.457 0.000
R04.2 Haemoptysis
0.543 0.457 0.000
I51 Complications and ill-defined descriptions of heart disease
0.542 0.458 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.542 0.458 0.000
N21 Calculus of lower urinary tract
0.542 0.458 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.542 0.458 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.542 0.458 0.000
Y98 Lifestyle-related condition
0.542 0.458 0.000
Y97 Environmental-pollution-related condition
0.542 0.458 0.000
Y96 Work-related condition
0.542 0.458 0.000
H36 Retinal disorders in diseases classified elsewhere
0.542 0.458 0.000
H34 Retinal vascular occlusions
0.542 0.458 0.000
H33 Retinal detachments and breaks
0.542 0.458 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.542 0.458 0.000
H31 Other disorders of choroid
0.542 0.458 0.000
H30 Chorioretinal inflammation
0.542 0.458 0.000
I47 Paroxysmal tachycardia
0.541 0.459 0.000
R12 Heartburn
0.541 0.459 0.000
Z50 Care involving use of rehabilitation procedures
0.541 0.459 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.541 0.459 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.540 0.460 0.000
N85.2 Hypertrophy of uterus
0.540 0.460 0.000
W19 Unspecified fall
0.540 0.460 0.000
I52 Other heart disorders in diseases classified elsewhere
0.539 0.461 0.000
I48 Atrial fibrillation and flutter
0.539 0.461 0.000
I46 Cardiac arrest
0.539 0.461 0.000
I45 Other conduction disorders
0.539 0.461 0.000
I44 Atrioventricular and left bundle-branch block
0.539 0.461 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.539 0.461 0.000
I42 Cardiomyopathy
0.539 0.461 0.000
I41 Myocarditis in diseases classified elsewhere
0.539 0.461 0.000
I40 Acute myocarditis
0.539 0.461 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.539 0.461 0.000
I37 Pulmonary valve disorders
0.539 0.461 0.000
I36 Nonrheumatic tricuspid valve disorders
0.539 0.461 0.000
I35 Nonrheumatic aortic valve disorders
0.539 0.461 0.000
I34 Nonrheumatic mitral valve disorders
0.539 0.461 0.000
I33 Acute and subacute endocarditis
0.539 0.461 0.000
I32 Pericarditis in diseases classified elsewhere
0.539 0.461 0.000
I31 Other diseases of pericardium
0.539 0.461 0.000
I30 Acute pericarditis
0.539 0.461 0.000
I38 Endocarditis, valve unspecified
0.539 0.461 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.539 0.461 0.000
R20 Disturbances of skin sensation
0.538 0.461 0.000
I24 Other acute ischaemic heart diseases
0.538 0.462 0.000
I23 Certain current complications following acute myocardial infarction
0.538 0.462 0.000
I22 Subsequent myocardial infarction
0.538 0.462 0.000
I26 Pulmonary embolism
0.538 0.462 0.000
K25 Gastric ulcer
0.538 0.462 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.535 0.464 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.535 0.464 0.000
R04.1 Haemorrhage from throat
0.535 0.464 0.000
I20.9 Angina pectoris, unspecified
0.535 0.464 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.534 0.466 0.000
N84.1 Polyp of cervix uteri
0.533 0.467 0.000
K50 Crohn's disease [regional enteritis]
0.531 0.469 0.000
Chapter V Mental and behavioural disorders
0.530 0.469 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.530 0.470 0.000
D50-D53 Nutritional anaemias
0.529 0.471 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.529 0.471 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.529 0.471 0.000
J60-J70 Lung diseases due to external agents
0.529 0.471 0.000
J00-J06 Acute upper respiratory infections
0.529 0.471 0.000
N73 Other female pelvic inflammatory diseases
0.529 0.471 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.529 0.471 0.000
N27 Small kidney of unknown cause
0.529 0.471 0.000
N25 Disorders resulting from impaired renal tubular function
0.529 0.471 0.000
N26 Unspecified contracted kidney
0.529 0.471 0.000
D17 Benign lipomatous neoplasm
0.528 0.472 0.000
Z80.3 Family history of malignant neoplasm of breast
0.528 0.472 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.528 0.472 0.000
C66 Malignant neoplasm of ureter
0.528 0.472 0.000
C65 Malignant neoplasm of renal pelvis
0.528 0.472 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.528 0.472 0.000
N50 Other disorders of male genital organs
0.527 0.472 0.000
H35.3 Degeneration of macula and posterior pole
0.526 0.474 0.000
Z92.3 Personal history of irradiation
0.526 0.474 0.000
K29.9 Gastroduodenitis, unspecified
0.525 0.475 0.000
K29.4 Chronic atrophic gastritis
0.525 0.475 0.000
K29.3 Chronic superficial gastritis
0.525 0.475 0.000
K29.2 Alcoholic gastritis
0.525 0.475 0.000
K29.1 Other acute gastritis
0.525 0.475 0.000
K29.0 Acute haemorrhagic gastritis
0.525 0.475 0.000
C18 Malignant neoplasm of colon
0.525 0.475 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.524 0.476 0.000
N64 Other disorders of breast
0.524 0.476 0.000
N60 Benign mammary dysplasia
0.524 0.476 0.000
N62 Hypertrophy of breast
0.524 0.476 0.000
N61 Inflammatory disorders of breast
0.524 0.476 0.000
R27 Other lack of coordination
0.523 0.476 0.000
R25 Abnormal involuntary movements
0.523 0.476 0.000
Z02.8 Other examinations for administrative purposes
0.522 0.478 0.000
R63 Symptoms and signs concerning food and fluid intake
0.522 0.478 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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