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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs193031333
log Bayes Factor = 7.91451
Chromosome 16   position 79,189,810  (GRCh37) Explore rs193031333 on Ensembl!
Variant rs193031333 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.987 0.013 0.000
Chapter II Neoplasms
0.985 0.015 0.000
O60-O75 Complications of labour and delivery
0.983 0.017 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Chapter XIV Diseases of the genitourinary system
0.966 0.034 0.000
H30-H36 Disorders of choroid and retina
0.965 0.035 0.000
N30-N39 Other diseases of urinary system
0.951 0.049 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.948 0.052 0.000
C64-C68 Malignant neoplasms of urinary tract
0.938 0.062 0.000
H43-H45 Disorders of vitreous body and globe
0.929 0.071 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.925 0.075 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.924 0.076 0.000
N39 Other disorders of urinary system
0.915 0.085 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.913 0.087 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.911 0.089 0.000
N40-N51 Diseases of male genital organs
0.911 0.089 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.909 0.091 0.000
Chapter XI Diseases of the digestive system
0.904 0.096 0.000
H33 Retinal detachments and breaks
0.903 0.097 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.903 0.097 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.903 0.097 0.000
Chapter VIII Diseases of the ear and mastoid process
0.898 0.102 0.000
N10-N16 Renal tubulo-interstitial diseases
0.894 0.106 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.889 0.111 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.888 0.112 0.000
N39.3 Stress incontinence
0.883 0.117 0.000
T81 Complications of procedures, not elsewhere classified
0.882 0.118 0.000
H43 Disorders of vitreous body
0.882 0.118 0.000
K70-K77 Diseases of liver
0.875 0.125 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.873 0.127 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.873 0.127 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.870 0.130 0.000
D60-D64 Aplastic and other anaemias
0.867 0.133 0.000
Chapter IX Diseases of the circulatory system
0.866 0.134 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.866 0.134 0.000
C67 Malignant neoplasm of bladder
0.865 0.135 0.000
N35 Urethral stricture
0.865 0.135 0.000
C15-C26 Malignant neoplasms of digestive organs
0.864 0.136 0.000
D00-D09 In situ neoplasms
0.863 0.137 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.860 0.140 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.859 0.141 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.855 0.145 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
H33.0 Retinal detachment with retinal break
0.851 0.149 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.851 0.149 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.849 0.151 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
N48 Other disorders of penis
0.843 0.157 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.840 0.160 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.838 0.162 0.000
H36 Retinal disorders in diseases classified elsewhere
0.835 0.165 0.000
C18 Malignant neoplasm of colon
0.830 0.170 0.000
O62 Abnormalities of forces of labour
0.825 0.175 0.000
G40-G47 Episodic and paroxysmal disorders
0.819 0.181 0.000
G90-G99 Other disorders of the nervous system
0.816 0.184 0.000
D64 Other anaemias
0.815 0.184 0.000
N32 Other disorders of bladder
0.815 0.185 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.815 0.185 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.813 0.187 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.810 0.190 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.806 0.194 0.000
C18.7 Sigmoid colon
0.805 0.195 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.803 0.197 0.000
N35.9 Urethral stricture, unspecified
0.803 0.197 0.000
Chapter XXII Codes for special purposes
0.801 0.199 0.000
H55-H59 Other disorders of eye and adnexa
0.801 0.199 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.800 0.200 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.798 0.202 0.000
G20-G26 Extrapyramidal and movement disorders
0.798 0.202 0.000
O47 False labour
0.798 0.202 0.000
K74 Fibrosis and cirrhosis of liver
0.796 0.204 0.000
A00-A09 Intestinal infectious diseases
0.796 0.204 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.795 0.205 0.000
O72 Postpartum haemorrhage
0.794 0.206 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.794 0.206 0.000
N32.8 Other specified disorders of bladder
0.789 0.211 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.788 0.212 0.000
H43.8 Other disorders of vitreous body
0.786 0.214 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.785 0.215 0.000
H80-H83 Diseases of inner ear
0.784 0.216 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.784 0.216 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.783 0.217 0.000
C67.9 Bladder, unspecified
0.783 0.217 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.781 0.219 0.000
D64.9 Anaemia, unspecified
0.779 0.221 0.000
N10 Acute tubulo-interstitial nephritis
0.778 0.222 0.000
K70 Alcoholic liver disease
0.776 0.224 0.000
H35 Other retinal disorders
0.776 0.224 0.000
C77.0 Lymph nodes of head, face and neck
0.774 0.226 0.000
K01 Embedded and impacted teeth
0.773 0.227 0.000
G70-G73 Diseases of myoneural junction and muscle
0.773 0.227 0.000
I84 Haemorrhoids
0.773 0.227 0.000
G35 Multiple sclerosis
0.772 0.228 0.000
K65-K67 Diseases of peritoneum
0.772 0.228 0.000
G30-G32 Other degenerative diseases of the nervous system
0.765 0.234 0.000
A80-A89 Viral infections of the central nervous system
0.763 0.237 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.763 0.237 0.000
O48 Prolonged pregnancy
0.761 0.239 0.000
H53-H54 Visual disturbances and blindness
0.759 0.241 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.757 0.243 0.000
M70-M79 Other soft tissue disorders
0.756 0.244 0.000
O16 Unspecified maternal hypertension
0.756 0.244 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.755 0.245 0.000
N99-N99 Other disorders of the genitourinary system
0.754 0.246 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.754 0.246 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.753 0.246 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.752 0.248 0.000
H10-H13 Disorders of conjunctiva
0.752 0.248 0.000
K08 Other disorders of teeth and supporting structures
0.751 0.249 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.750 0.250 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.749 0.251 0.000
H43.1 Vitreous haemorrhage
0.746 0.253 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.745 0.255 0.000
I84.6 Residual haemorrhoidal skin tags
0.744 0.256 0.000
D05 Carcinoma in situ of breast
0.744 0.256 0.000
G93 Other disorders of brain
0.743 0.257 0.000
H34 Retinal vascular occlusions
0.742 0.258 0.000
H36.0 Diabetic retinopathy
0.741 0.259 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.741 0.259 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.739 0.261 0.000
K14 Diseases of tongue
0.738 0.262 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.736 0.264 0.000
H90-H95 Other disorders of ear
0.736 0.264 0.000
H33.4 Traction detachment of retina
0.736 0.264 0.000
T81.9 Unspecified complication of procedure
0.735 0.265 0.000
D50-D53 Nutritional anaemias
0.734 0.266 0.000
C77.1 Intrathoracic lymph nodes
0.733 0.267 0.000
N48.8 Other specified disorders of penis
0.732 0.268 0.000
C79 Secondary malignant neoplasm of other sites
0.731 0.269 0.000
N39.4 Other specified urinary incontinence
0.730 0.270 0.000
S70-S79 Injuries to the hip and thigh
0.729 0.271 0.000
K74.6 Other and unspecified cirrhosis of liver
0.728 0.272 0.000
B15-B19 Viral hepatitis
0.727 0.273 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.726 0.274 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.723 0.276 0.000
N36 Other disorders of urethra
0.722 0.278 0.000
H43.3 Other vitreous opacities
0.721 0.279 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.720 0.280 0.000
C71 Malignant neoplasm of brain
0.720 0.280 0.000
N34 Urethritis and urethral syndrome
0.720 0.280 0.000
A30-A49 Other bacterial diseases
0.719 0.280 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.716 0.283 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.716 0.283 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.287 0.000
M20-M25 Other joint disorders
0.713 0.287 0.000
M80-M85 Disorders of bone density and structure
0.713 0.287 0.000
K01.1 Impacted teeth
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.711 0.289 0.000
O62.2 Other uterine inertia
0.711 0.289 0.000
O66 Other obstructed labour
0.711 0.289 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
I80 Phlebitis and thrombophlebitis
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
K76 Other diseases of liver
0.708 0.292 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
O74 Complications of anaesthesia during labour and delivery
0.705 0.295 0.000
O71 Other obstetric trauma
0.705 0.295 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.705 0.295 0.000
O61 Failed induction of labour
0.705 0.295 0.000
O60 Preterm delivery
0.705 0.295 0.000
C51-C58 Malignant neoplasms of female genital organs
0.704 0.296 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.703 0.297 0.000
Q60-Q64 Congenital malformations of the urinary system
0.702 0.298 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.702 0.298 0.000
C77.5 Intrapelvic lymph nodes
0.702 0.298 0.000
N60-N64 Disorders of breast
0.702 0.298 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.701 0.299 0.000
N43 Hydrocele and spermatocele
0.701 0.299 0.000
B35-B49 Mycoses
0.701 0.299 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.699 0.301 0.000
M86-M90 Other osteopathies
0.698 0.302 0.000
G43 Migraine
0.697 0.303 0.000
Chapter XXI Factors influencing health status and contact with health services
0.696 0.304 0.000
O64.1 Obstructed labour due to breech presentation
0.695 0.305 0.000
K70.3 Alcoholic cirrhosis of liver
0.695 0.305 0.000
C67.5 Bladder neck
0.694 0.306 0.000
K08.3 Retained dental root
0.693 0.307 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.693 0.307 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.693 0.307 0.000
K09 Cysts of oral region, not elsewhere classified
0.693 0.307 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.692 0.308 0.000
H31 Other disorders of choroid
0.692 0.308 0.000
H30 Chorioretinal inflammation
0.692 0.308 0.000
O72.0 Third-stage haemorrhage
0.692 0.308 0.000
N45 Orchitis and epididymitis
0.691 0.308 0.000
N48.2 Other inflammatory disorders of penis
0.690 0.310 0.000
H44 Disorders of globe
0.688 0.312 0.000
O73 Retained placenta and membranes, without haemorrhage
0.688 0.312 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.688 0.312 0.000
H83 Other diseases of inner ear
0.688 0.312 0.000
I05-I09 Chronic rheumatic heart diseases
0.687 0.313 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.687 0.313 0.000
M65-M68 Disorders of synovium and tendon
0.687 0.313 0.000
I85 Oesophageal varices
0.686 0.314 0.000
H18 Other disorders of cornea
0.686 0.314 0.000
O63 Long labour
0.686 0.314 0.000
H21 Other disorders of iris and ciliary body
0.685 0.315 0.000
H17 Corneal scars and opacities
0.684 0.316 0.000
S40-S49 Injuries to the shoulder and upper arm
0.684 0.316 0.000
O47.0 False labour before 37 completed weeks of gestation
0.684 0.316 0.000
N37 Urethral disorders in diseases classified elsewhere
0.682 0.318 0.000
N33 Bladder disorders in diseases classified elsewhere
0.682 0.318 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.681 0.318 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.680 0.320 0.000
O97 Death from sequelae of direct obstetric causes
0.680 0.320 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.680 0.320 0.000
O95 Obstetric death of unspecified cause
0.680 0.320 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.680 0.320 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.679 0.320 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.679 0.321 0.000
H20 Iridocyclitis
0.679 0.321 0.000
I88 Nonspecific lymphadenitis
0.675 0.325 0.000
N48.6 Balanitis xerotica obliterans
0.675 0.325 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
N48.0 Leukoplakia of penis
0.673 0.327 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.672 0.328 0.000
C66 Malignant neoplasm of ureter
0.672 0.328 0.000
C65 Malignant neoplasm of renal pelvis
0.672 0.328 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.672 0.328 0.000
G20 Parkinson's disease
0.671 0.329 0.000
H60-H62 Diseases of external ear
0.671 0.329 0.000
N39.8 Other specified disorders of urinary system
0.670 0.329 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.670 0.330 0.000
G40 Epilepsy
0.670 0.330 0.000
C77.4 Inguinal and lower limb lymph nodes
0.668 0.332 0.000
I87 Other disorders of veins
0.667 0.332 0.000
D62 Acute posthaemorrhagic anaemia
0.667 0.333 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.666 0.334 0.000
K31 Other diseases of stomach and duodenum
0.666 0.334 0.000
C50-C50 Malignant neoplasm of breast
0.664 0.336 0.000
N39.0 Urinary tract infection, site not specified
0.664 0.336 0.000
I84.4 External haemorrhoids with other complications
0.663 0.337 0.000
O45 Premature separation of placenta [abruptio placentae]
0.663 0.337 0.000
O44 Placenta praevia
0.663 0.337 0.000
O43 Placental disorders
0.663 0.337 0.000
O41 Other disorders of amniotic fluid and membranes
0.663 0.337 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.663 0.337 0.000
O33 Maternal care for known or suspected disproportion
0.663 0.337 0.000
O31 Complications specific to multiple gestation
0.663 0.337 0.000
O40 Polyhydramnios
0.663 0.337 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.663 0.337 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.661 0.339 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.660 0.339 0.000
G37 Other demyelinating diseases of central nervous system
0.660 0.340 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.660 0.340 0.000
O42 Premature rupture of membranes
0.659 0.341 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.659 0.341 0.000
H35.8 Other specified retinal disorders
0.659 0.341 0.000
O00-O08 Pregnancy with abortive outcome
0.658 0.342 0.000
K66 Other disorders of peritoneum
0.658 0.342 0.000
N39.2 Orthostatic proteinuria, unspecified
0.656 0.344 0.000
N39.1 Persistent proteinuria, unspecified
0.656 0.344 0.000
C18.9 Colon, unspecified
0.656 0.344 0.000
I84.8 Unspecified haemorrhoids with other complications
0.656 0.344 0.000
O70 Perineal laceration during delivery
0.655 0.344 0.000
I78 Diseases of capillaries
0.656 0.344 0.000
O15 Eclampsia
0.654 0.345 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.654 0.345 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.654 0.345 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.654 0.345 0.000
K04 Diseases of pulp and periapical tissues
0.654 0.346 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.653 0.346 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.653 0.347 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.653 0.347 0.000
N46 Male infertility
0.653 0.347 0.000
N44 Torsion of testis
0.653 0.347 0.000
H90 Conductive and sensorineural hearing loss
0.652 0.348 0.000
G80 Infantile cerebral palsy
0.652 0.348 0.000
D55-D59 Haemolytic anaemias
0.652 0.348 0.000
M79.6 Pain in limb
0.652 0.348 0.000
A08 Viral and other specified intestinal infections
0.652 0.348 0.000
K25 Gastric ulcer
0.651 0.349 0.000
K72 Hepatic failure, not elsewhere classified
0.651 0.349 0.000
H57 Other disorders of eye and adnexa
0.650 0.350 0.000
D04 Carcinoma in situ of skin
0.649 0.351 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.648 0.351 0.000
C25 Malignant neoplasm of pancreas
0.648 0.352 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.648 0.352 0.000
H33.5 Other retinal detachments
0.648 0.352 0.000
H33.1 Retinoschisis and retinal cysts
0.648 0.352 0.000
T79-T79 Certain early complications of trauma
0.647 0.352 0.000
T33-T35 Frostbite
0.647 0.352 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.647 0.352 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.647 0.352 0.000
T00-T07 Injuries involving multiple body regions
0.647 0.352 0.000
S10-S19 Injuries to the neck
0.647 0.352 0.000
T66-T78 Other and unspecified effects of external causes
0.647 0.353 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.647 0.353 0.000
C16 Malignant neoplasm of stomach
0.646 0.354 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.646 0.354 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.645 0.355 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.644 0.356 0.000
N17-N19 Renal failure
0.643 0.357 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.643 0.357 0.000
M23 Internal derangement of knee
0.642 0.358 0.000
H81 Disorders of vestibular function
0.642 0.358 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.641 0.359 0.000
N15 Other renal tubulo-interstitial diseases
0.641 0.359 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.641 0.359 0.000
N11 Chronic tubulo-interstitial nephritis
0.641 0.359 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.639 0.361 0.000
D03 Melanoma in situ
0.639 0.361 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.638 0.362 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.638 0.362 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.637 0.363 0.000
O80-O84 Delivery
0.636 0.363 0.000
T87 Complications peculiar to reattachment and amputation
0.636 0.363 0.000
N13 Obstructive and reflux uropathy
0.636 0.364 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.636 0.364 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.636 0.364 0.000
B25-B34 Other viral diseases
0.636 0.364 0.000
C67.4 Posterior wall of bladder
0.634 0.366 0.000
H16 Keratitis
0.634 0.366 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.633 0.367 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.633 0.367 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.633 0.367 0.000
H43.9 Disorder of vitreous body, unspecified
0.632 0.367 0.000
H43.2 Crystalline deposits in vitreous body
0.632 0.367 0.000
H43.0 Vitreous prolapse
0.632 0.367 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.632 0.368 0.000
D80-D89 Certain disorders involving the immune mechanism
0.631 0.369 0.000
M91-M94 Chondropathies
0.631 0.369 0.000
O30 Multiple gestation
0.630 0.370 0.000
C67.2 Lateral wall of bladder
0.630 0.370 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.630 0.370 0.000
C77.9 Lymph node, unspecified
0.630 0.370 0.000
H33.2 Serous retinal detachment
0.630 0.370 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.629 0.371 0.000
C69 Malignant neoplasm of eye and adnexa
0.629 0.371 0.000
D50 Iron deficiency anaemia
0.629 0.371 0.000
G71 Primary disorders of muscles
0.628 0.372 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.627 0.373 0.000
K77 Liver disorders in diseases classified elsewhere
0.627 0.373 0.000
K73 Chronic hepatitis, not elsewhere classified
0.627 0.373 0.000
K71 Toxic liver disease
0.627 0.373 0.000
G95 Other diseases of spinal cord
0.627 0.373 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.626 0.374 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.626 0.374 0.000
H15 Disorders of sclera
0.626 0.374 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.626 0.374 0.000
C45 Mesothelioma
0.626 0.374 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.624 0.376 0.000
O32.1 Maternal care for breech presentation
0.624 0.376 0.000
Q00-Q07 Congenital malformations of the nervous system
0.623 0.377 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.622 0.378 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.622 0.378 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.621 0.379 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.621 0.379 0.000
I00-I02 Acute rheumatic fever
0.621 0.379 0.000
G36 Other acute disseminated demyelination
0.621 0.379 0.000
G82 Paraplegia and tetraplegia
0.621 0.379 0.000
C67.8 Overlapping lesion of bladder
0.620 0.380 0.000
C67.7 Urachus
0.620 0.380 0.000
C67.6 Ureteric orifice
0.620 0.380 0.000
C67.3 Anterior wall of bladder
0.620 0.380 0.000
C67.1 Dome of bladder
0.620 0.380 0.000
C67.0 Trigone of bladder
0.620 0.380 0.000
O36 Maternal care for other known or suspected foetal problems
0.620 0.380 0.000
N35.8 Other urethral stricture
0.620 0.380 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.620 0.380 0.000
N35.0 Posttraumatic urethral stricture
0.620 0.380 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.619 0.380 0.000
C21 Malignant neoplasm of anus and anal canal
0.619 0.380 0.000
C17 Malignant neoplasm of small intestine
0.619 0.380 0.000
C23 Malignant neoplasm of gallbladder
0.619 0.380 0.000
C80 Malignant neoplasm without specification of site
0.619 0.381 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.619 0.381 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.619 0.381 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.619 0.381 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.619 0.381 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.618 0.381 0.000
H83.0 Labyrinthitis
0.618 0.381 0.000
M23.3 Other meniscus derangements
0.618 0.382 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.618 0.382 0.000
G93.8 Other specified disorders of brain
0.617 0.383 0.000
C77.8 Lymph nodes of multiple regions
0.617 0.383 0.000
K03 Other diseases of hard tissues of teeth
0.616 0.384 0.000
K00 Disorders of tooth development and eruption
0.616 0.384 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.616 0.384 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.615 0.385 0.000
K05 Gingivitis and periodontal diseases
0.615 0.385 0.000
C18.2 Ascending colon
0.614 0.386 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.614 0.386 0.000
M60-M63 Disorders of muscles
0.613 0.387 0.000
M00-M03 Infectious arthropathies
0.613 0.387 0.000
S72 Fracture of femur
0.612 0.388 0.000
D09 Carcinoma in situ of other and unspecified sites
0.612 0.388 0.000
C77.3 Axillary and upper limb lymph nodes
0.612 0.388 0.000
K74.3 Primary biliary cirrhosis
0.611 0.388 0.000
D46 Myelodysplastic syndromes
0.611 0.389 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.611 0.389 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.611 0.389 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.611 0.389 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.611 0.389 0.000
G12 Spinal muscular atrophy and related syndromes
0.611 0.389 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.611 0.389 0.000
C01 Malignant neoplasm of base of tongue
0.611 0.389 0.000
H65-H75 Diseases of middle ear and mastoid
0.610 0.390 0.000
O75.9 Complication of labour and delivery, unspecified
0.610 0.390 0.000
O75.8 Other specified complications of labour and delivery
0.610 0.390 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.610 0.390 0.000
O75.4 Other complications of obstetric surgery and procedures
0.610 0.390 0.000
O75.3 Other infection during labour
0.610 0.390 0.000
O75.1 Shock during or following labour and delivery
0.610 0.390 0.000
O75.0 Maternal distress during labour and delivery
0.610 0.390 0.000
C18.5 Splenic flexure
0.609 0.390 0.000
K07 Dentofacial anomalies [including malocclusion]
0.609 0.390 0.000
A04 Other bacterial intestinal infections
0.609 0.390 0.000
G43.9 Migraine, unspecified
0.609 0.391 0.000
N32.3 Diverticulum of bladder
0.609 0.391 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.608 0.392 0.000
M25 Other joint disorders, not elsewhere classified
0.608 0.392 0.000
K70.1 Alcoholic hepatitis
0.607 0.392 0.000
I82 Other venous embolism and thrombosis
0.607 0.393 0.000
I81 Portal vein thrombosis
0.607 0.393 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.606 0.394 0.000
I86 Varicose veins of other sites
0.606 0.394 0.000
D06 Carcinoma in situ of cervix uteri
0.606 0.394 0.000
D45 Polycythaemia vera
0.606 0.394 0.000
C71.1 Frontal lobe
0.606 0.394 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.606 0.394 0.000
Q80-Q89 Other congenital malformations
0.606 0.394 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.606 0.394 0.000
Q35-Q37 Cleft lip and cleft palate
0.606 0.394 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.606 0.394 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.606 0.394 0.000
T92 Sequelae of injuries of upper limb
0.605 0.395 0.000
N48.9 Disorder of penis, unspecified
0.604 0.396 0.000
N48.5 Ulcer of penis
0.604 0.396 0.000
N48.3 Priapism
0.604 0.396 0.000
G44 Other headache syndromes
0.604 0.396 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.603 0.397 0.000
N00-N08 Glomerular diseases
0.603 0.397 0.000
N63 Unspecified lump in breast
0.603 0.397 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.601 0.398 0.000
K75 Other inflammatory liver diseases
0.601 0.399 0.000
G47 Sleep disorders
0.601 0.399 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.601 0.399 0.000
C70 Malignant neoplasm of meninges
0.601 0.399 0.000
K11 Diseases of salivary glands
0.601 0.399 0.000
N39.9 Disorder of urinary system, unspecified
0.599 0.400 0.000
Z37 Outcome of delivery
0.599 0.401 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.599 0.401 0.000
Q50-Q56 Congenital malformations of genital organs
0.598 0.402 0.000
H55 Nystagmus and other irregular eye movements
0.598 0.402 0.000
I74 Arterial embolism and thrombosis
0.597 0.403 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.597 0.403 0.000
K14.0 Glossitis
0.596 0.404 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.596 0.404 0.000
K14.8 Other diseases of tongue
0.596 0.404 0.000
C18.8 Overlapping lesion of colon
0.595 0.405 0.000
C18.6 Descending colon
0.595 0.405 0.000
C18.3 Hepatic flexure
0.595 0.405 0.000
C18.1 Appendix
0.595 0.405 0.000
T93 Sequelae of injuries of lower limb
0.595 0.405 0.000
A87 Viral meningitis
0.594 0.406 0.000
H33.3 Retinal breaks without detachment
0.592 0.408 0.000
O62.9 Abnormality of forces of labour, unspecified
0.591 0.409 0.000
O62.8 Other abnormalities of forces of labour
0.591 0.409 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.591 0.409 0.000
O62.3 Precipitate labour
0.591 0.409 0.000
O62.1 Secondary uterine inertia
0.591 0.409 0.000
O62.0 Primary inadequate contractions
0.591 0.409 0.000
K65 Peritonitis
0.591 0.409 0.000
G93.4 Encephalopathy, unspecified
0.591 0.409 0.000
N32.1 Vesicointestinal fistula
0.590 0.409 0.000
K10 Other diseases of jaws
0.590 0.410 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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