TreeWAS – Variant ID: rs1968498

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter X Diseases of the respiratory system	0.998	0.002
Chapter XV Pregnancy, childbirth and the puerperium	0.997	0.003
Chapter VI Diseases of the nervous system	0.995	0.005
Chapter XIV Diseases of the genitourinary system	0.995	0.005
I60-I69 Cerebrovascular diseases	0.994	0.006
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.990	0.010
N17-N19 Renal failure	0.989	0.011
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.984	0.016
Chapter VII Diseases of the eye and adnexa	0.983	0.017
J95-J99 Other diseases of the respiratory system	0.976	0.024
M45-M49 Spondylopathies	0.975	0.025
N17 Acute renal failure	0.974	0.026
I60 Subarachnoid haemorrhage	0.971	0.029
N20-N23 Urolithiasis	0.966	0.034
J90-J94 Other diseases of pleura	0.966	0.034
N17.9 Acute renal failure, unspecified	0.963	0.037
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.961	0.039
M47 Spondylosis	0.961	0.039
J98 Other respiratory disorders	0.960	0.040
G40-G47 Episodic and paroxysmal disorders	0.957	0.043
G90-G99 Other disorders of the nervous system	0.955	0.045
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.954	0.046
G45 Transient cerebral ischaemic attacks and related syndromes	0.951	0.049
G45.9 Transient cerebral ischaemic attack, unspecified	0.948	0.052
R30-R39 Symptoms and signs involving the urinary system	0.947	0.053
H04 Disorders of lachrymal system	0.947	0.053
I60.9 Subarachnoid haemorrhage, unspecified	0.946	0.054
Chapter I Certain infectious and parasitic diseases	0.946	0.054
N00-N08 Glomerular diseases	0.943	0.057
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.943	0.057
J98.4 Other disorders of lung	0.938	0.062
N18 Chronic renal failure	0.930	0.070
R32 Unspecified urinary incontinence	0.929	0.071
I95-I99 Other and unspecified disorders of the circulatory system	0.925	0.075
I10-I15 Hypertensive diseases	0.923	0.077
M40-M43 Deforming dorsopathies	0.916	0.084
J90 Pleural effusion, not elsewhere classified	0.916	0.084
I65.2 Occlusion and stenosis of carotid artery	0.907	0.093
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.905	0.095
M47.2 Other spondylosis with radiculopathy	0.901	0.099
J09-J18 Influenza and pneumonia	0.901	0.099
G80-G83 Cerebral palsy and other paralytic syndromes	0.894	0.106
G95 Other diseases of spinal cord	0.893	0.107
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.892	0.108
N21 Calculus of lower urinary tract	0.891	0.109
O47 False labour	0.890	0.110
O32 Maternal care for known or suspected malpresentation of foetus	0.890	0.110
Chapter VIII Diseases of the ear and mastoid process	0.889	0.111
I70-I79 Diseases of arteries, arterioles and capillaries	0.887	0.113
I95 Hypotension	0.887	0.113
J60-J70 Lung diseases due to external agents	0.885	0.115
N20 Calculus of kidney and ureter	0.884	0.116
M47.9 Spondylosis, unspecified	0.884	0.116
O94-O99 Other obstetric conditions, not elsewhere classified	0.877	0.123
M86-M90 Other osteopathies	0.877	0.123
I12 Hypertensive renal disease	0.874	0.126
N20.1 Calculus of ureter	0.873	0.127
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.871	0.129
I30-I52 Other forms of heart disease	0.870	0.130
I95.1 Orthostatic hypotension	0.868	0.132
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.868	0.132
H46-H48 Disorders of optic nerve and visual pathways	0.864	0.136
N18.5 Chronic kidney disease, stage 5	0.863	0.137
H04.1 Other disorders of lachrymal gland	0.863	0.137
I67 Other cerebrovascular diseases	0.861	0.139
Chapter XX External causes of morbidity and mortality	0.858	0.142
M48 Other spondylopathies	0.857	0.142
I50 Heart failure	0.856	0.144
H04.2 Epiphora	0.855	0.145
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.852	0.148
I50.0 Congestive heart failure	0.850	0.150
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.850	0.150
O48 Prolonged pregnancy	0.846	0.154
A30-A49 Other bacterial diseases	0.844	0.156
O47.1 False labour at or after 37 completed weeks of gestation	0.843	0.157
M43 Other deforming dorsopathies	0.843	0.157
R31 Unspecified haematuria	0.842	0.158
N21.0 Calculus in bladder	0.838	0.162
H04.5 Stenosis and insufficiency of lachrymal passages	0.836	0.164
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.833	0.167
R30 Pain associated with micturition	0.832	0.168
I12.0 Hypertensive renal disease with renal failure	0.831	0.169
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.826	0.174
H20 Iridocyclitis	0.826	0.174
J11 Influenza, virus not identified	0.825	0.175
O34 Maternal care for known or suspected abnormality of pelvic organs	0.823	0.177
Chapter IV Endocrine, nutritional and metabolic diseases	0.821	0.179
G70-G73 Diseases of myoneural junction and muscle	0.820	0.180
R20 Disturbances of skin sensation	0.819	0.181
J98.1 Pulmonary collapse	0.816	0.184
H53-H54 Visual disturbances and blindness	0.813	0.187
G91 Hydrocephalus	0.813	0.187
M47.8 Other spondylosis	0.812	0.188
J91 Pleural effusion in conditions classified elsewhere	0.812	0.188
R20.8 Other and unspecified disturbances of skin sensation	0.810	0.190
N40-N51 Diseases of male genital organs	0.808	0.192
O00-O08 Pregnancy with abortive outcome	0.807	0.193
O35 Maternal care for known or suspected foetal abnormality and damage	0.807	0.193
N08 Glomerular disorders in diseases classified elsewhere	0.803	0.197
B95-B98 Bacterial, viral and other infectious agents	0.801	0.199
G83 Other paralytic syndromes	0.798	0.202
M47.92 Spondylosis, unspecified (Cervical region)	0.796	0.204
Y52 Agents primarily affecting the cardiovascular system	0.792	0.208
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.792	0.208
J69 Pneumonitis due to solids and liquids	0.789	0.211
G95.2 Cord compression, unspecified	0.789	0.211
E20-E35 Disorders of other endocrine glands	0.787	0.213
M45 Ankylosing spondylitis	0.786	0.214
N18.0 End-stage renal disease	0.784	0.216
J86 Pyothorax	0.780	0.220
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.780	0.220
H65-H75 Diseases of middle ear and mastoid	0.779	0.221
I73 Other peripheral vascular diseases	0.779	0.221
R46 Symptoms and signs involving appearance and behaviour	0.777	0.222
N05 Unspecified nephritic syndrome	0.777	0.223
J99 Respiratory disorders in diseases classified elsewhere	0.777	0.223
N03 Chronic nephritic syndrome	0.775	0.225
I46 Cardiac arrest	0.775	0.225
O36 Maternal care for other known or suspected foetal problems	0.774	0.226
N18.3 Chronic kidney disease, stage 3	0.771	0.229
J11.1 Influenza with other respiratory manifestations, virus not identified	0.771	0.229
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.771	0.229
R47-R49 Symptoms and signs involving speech and voice	0.770	0.230
I20-I25 Ischaemic heart diseases	0.770	0.230
O32.1 Maternal care for breech presentation	0.769	0.231
I11 Hypertensive heart disease	0.767	0.233
H47 Other disorders of optic [2nd] nerve and visual pathways	0.767	0.233
O44 Placenta praevia	0.766	0.234
I62 Other nontraumatic intracranial haemorrhage	0.766	0.234
M48.0 Spinal stenosis	0.766	0.234
H05 Disorders of orbit	0.765	0.235
G95.1 Vascular myelopathies	0.764	0.235
G99 Other disorders of nervous system in diseases classified elsewhere	0.764	0.236
H04.3 Acute and unspecified inflammation of lachrymal passages	0.764	0.236
O41 Other disorders of amniotic fluid and membranes	0.762	0.238
M00-M03 Infectious arthropathies	0.760	0.240
H55-H59 Other disorders of eye and adnexa	0.759	0.241
M65-M68 Disorders of synovium and tendon	0.757	0.243
N02 Recurrent and persistent haematuria	0.756	0.243
I61 Intracerebral haemorrhage	0.755	0.245
H60-H62 Diseases of external ear	0.754	0.246
M43.1 Spondylolisthesis	0.753	0.247
O85-O92 Complications predominantly related to the puerperium	0.753	0.247
J80-J84 Other respiratory diseases principally affecting the interstitium	0.752	0.248
H53 Visual disturbances	0.752	0.248
I77 Other disorders of arteries and arterioles	0.752	0.248
O04 Medical abortion	0.751	0.249
J13 Pneumonia due to Streptococcus pneumoniae	0.750	0.250
Y57 Other and unspecified drugs and medicaments	0.749	0.251
R30.0 Dysuria	0.749	0.251
N47 Redundant prepuce, phimosis and paraphimosis	0.748	0.252
I25 Chronic ischaemic heart disease	0.748	0.252
R40 Somnolence, stupor and coma	0.748	0.252
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.747	0.253
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.747	0.253
H50 Other strabismus	0.747	0.253
M89 Other disorders of bone	0.747	0.253
M41 Scoliosis	0.745	0.255
J00-J06 Acute upper respiratory infections	0.744	0.256
M05-M14 Inflammatory polyarthropathies	0.743	0.257
I78 Diseases of capillaries	0.742	0.258
M48.06 Spinal stenosis (Lumbar region)	0.741	0.259
J92 Pleural plaque	0.741	0.259
G45.3 Amaurosis fugax	0.740	0.260
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.739	0.261
J15 Bacterial pneumonia, not elsewhere classified	0.739	0.261
M80-M85 Disorders of bone density and structure	0.738	0.262
G20-G26 Extrapyramidal and movement disorders	0.737	0.263
N18.9 Chronic renal failure, unspecified	0.736	0.264
J98.0 Diseases of bronchus, not elsewhere classified	0.735	0.265
N50 Other disorders of male genital organs	0.734	0.266
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.733	0.267
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.733	0.267
A49 Bacterial infection of unspecified site	0.733	0.267
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.732	0.268
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.731	0.269
J94 Other pleural conditions	0.730	0.270
G83.4 Cauda equina syndrome	0.729	0.271
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.728	0.272
O42 Premature rupture of membranes	0.728	0.272
M60-M63 Disorders of muscles	0.727	0.273
R42 Dizziness and giddiness	0.726	0.274
I33 Acute and subacute endocarditis	0.725	0.275
I73.0 Raynaud's syndrome	0.725	0.275
M91-M94 Chondropathies	0.724	0.276
N17.0 Acute renal failure with tubular necrosis	0.723	0.277
H04.4 Chronic inflammation of lachrymal passages	0.723	0.277
H04.8 Other disorders of lachrymal system	0.722	0.278
N23 Unspecified renal colic	0.721	0.279
G95.8 Other specified diseases of spinal cord	0.720	0.280
O60-O75 Complications of labour and delivery	0.720	0.280
J69.0 Pneumonitis due to food and vomit	0.720	0.280
B50-B64 Protozoal diseases	0.719	0.280
A00-A09 Intestinal infectious diseases	0.719	0.281
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.718	0.282
I15 Secondary hypertension	0.718	0.282
I46.9 Cardiac arrest, unspecified	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
O46 Antepartum haemorrhage, not elsewhere classified	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I25.2 Old myocardial infarction	0.715	0.285
M50-M54 Other dorsopathies	0.715	0.285
J86.9 Pyothorax without fistula	0.715	0.285
H20.8 Other iridocyclitis	0.714	0.286
Y52.4 Angiotensin-converting-enzyme inhibitors	0.714	0.286
G91.9 Hydrocephalus, unspecified	0.713	0.287
G82 Paraplegia and tetraplegia	0.713	0.287
I68 Cerebrovascular disorders in diseases classified elsewhere	0.712	0.287
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.712	0.287
O43 Placental disorders	0.712	0.288
R45 Symptoms and signs involving emotional state	0.711	0.289
O04.9 Complete or unspecified, without complication	0.710	0.290
N50.8 Other specified disorders of male genital organs	0.710	0.290
O45 Premature separation of placenta [abruptio placentae]	0.709	0.290
O33 Maternal care for known or suspected disproportion	0.709	0.290
O31 Complications specific to multiple gestation	0.709	0.290
M47.86 Other spondylosis (Lumbar region)	0.708	0.291
G90 Disorders of autonomic nervous system	0.708	0.292
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.706	0.294
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.705	0.295
G70 Myasthenia gravis and other myoneural disorders	0.705	0.295
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.704	0.296
M86 Osteomyelitis	0.704	0.296
M43.0 Spondylolysis	0.703	0.296
B90-B94 Sequelae of infectious and parasitic diseases	0.703	0.297
I05-I09 Chronic rheumatic heart diseases	0.702	0.298
B35-B49 Mycoses	0.702	0.298
E21.0 Primary hyperparathyroidism	0.701	0.299
A50-A64 Infections with a predominantly sexual mode of transmission	0.701	0.299
B99-B99 Other infectious diseases	0.701	0.299
H17 Corneal scars and opacities	0.701	0.299
H60 Otitis externa	0.701	0.299
H20.9 Iridocyclitis, unspecified	0.700	0.300
J96 Respiratory failure, not elsewhere classified	0.700	0.300
R82 Other abnormal findings in urine	0.700	0.300
O32.3 Maternal care for face, brow and chin presentation	0.700	0.300
M90 Osteopathies in diseases classified elsewhere	0.700	0.300
M49 Spondylopathies in diseases classified elsewhere	0.699	0.301
I63 Cerebral infarction	0.699	0.301
N17.8 Other acute renal failure	0.699	0.301
N17.2 Acute renal failure with medullary necrosis	0.699	0.301
N17.1 Acute renal failure with acute cortical necrosis	0.699	0.301
N08.3 Glomerular disorders in diabetes mellitus	0.698	0.302
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.698	0.302
A41 Other septicaemia	0.697	0.303
I60.8 Other subarachnoid haemorrhage	0.696	0.304
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.696	0.304
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.696	0.304
I60.5 Subarachnoid haemorrhage from vertebral artery	0.696	0.304
I60.4 Subarachnoid haemorrhage from basilar artery	0.696	0.304
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.696	0.304
R44 Other symptoms and signs involving general sensations and perceptions	0.695	0.304
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.695	0.305
N22 Calculus of urinary tract in diseases classified elsewhere	0.693	0.307
O34.2 Maternal care due to uterine scar from previous surgery	0.693	0.307
I25.8 Other forms of chronic ischaemic heart disease	0.693	0.307
I38 Endocarditis, valve unspecified	0.692	0.308
O80-O84 Delivery	0.691	0.309
I67.2 Cerebral atherosclerosis	0.690	0.310
R95-R99 Ill-defined and unknown causes of mortality	0.689	0.311
M47.0 Anterior spinal and vertebral artery compression syndromes	0.689	0.311
N04 Nephrotic syndrome	0.689	0.311
J98.9 Respiratory disorder, unspecified	0.688	0.311
J98.6 Disorders of diaphragm	0.688	0.311
J98.5 Diseases of mediastinum, not elsewhere classified	0.688	0.311
J98.3 Compensatory emphysema	0.688	0.311
J98.2 Interstitial emphysema	0.688	0.311
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.688	0.312
G44 Other headache syndromes	0.688	0.312
G46 Vascular syndromes of brain in cerebrovascular diseases	0.686	0.314
G94 Other disorders of brain in diseases classified elsewhere	0.685	0.315
G98 Other disorders of nervous system, not elsewhere classified	0.685	0.315
G92 Toxic encephalopathy	0.685	0.315
G41 Status epilepticus	0.685	0.315
H03 Disorders of eyelid in diseases classified elsewhere	0.684	0.316
N25-N29 Other disorders of kidney and ureter	0.684	0.316
G96 Other disorders of central nervous system	0.683	0.317
H52 Disorders of refraction and accommodation	0.683	0.317
O32.2 Maternal care for transverse and oblique lie	0.682	0.317
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.682	0.318
G45.2 Multiple and bilateral precerebral artery syndromes	0.682	0.318
G45.1 Carotid artery syndrome (hemispheric)	0.682	0.318
G45.0 Vertebro-basilar artery syndrome	0.682	0.318
R34 Anuria and oliguria	0.682	0.318
Y44 Agents primarily affecting blood constituents	0.681	0.319
M43.16 Spondylolisthesis (Lumbar region)	0.680	0.320
R36 Urethral discharge	0.679	0.321
I31 Other diseases of pericardium	0.679	0.321
H04.9 Disorder of lachrymal system, unspecified	0.679	0.321
H04.6 Other changes in lachrymal passages	0.679	0.321
H04.0 Dacryoadenitis	0.679	0.321
B85-B89 Pediculosis, acariasis and other infestations	0.678	0.322
B65-B83 Helminthiases	0.678	0.322
B20-B24 Human immunodeficiency virus [HIV] disease	0.678	0.322
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.678	0.322
A75-A79 Rickettsioses	0.678	0.322
A70-A74 Other diseases caused by chlamydiae	0.678	0.322
A65-A69 Other spirochaetal diseases	0.678	0.322
A20-A28 Certain zoonotic bacterial diseases	0.678	0.322
A15-A19 Tuberculosis	0.678	0.322
Y57.9 Drug or medicament, unspecified	0.677	0.323
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.676	0.324
N07 Hereditary nephropathy, not elsewhere classified	0.676	0.324
N06 Isolated proteinuria with specified morphological lesion	0.676	0.324
N01 Rapidly progressive nephritic syndrome	0.676	0.324
N00 Acute nephritic syndrome	0.676	0.324
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.676	0.324
I65.8 Occlusion and stenosis of other precerebral artery	0.676	0.324
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.676	0.324
I65.1 Occlusion and stenosis of basilar artery	0.676	0.324
I65.0 Occlusion and stenosis of vertebral artery	0.676	0.324
I42 Cardiomyopathy	0.676	0.324
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.675	0.325
Chapter XXII Codes for special purposes	0.674	0.325
I67.9 Cerebrovascular disease, unspecified	0.674	0.326
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.673	0.327
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.673	0.327
Y53 Agents primarily affecting the gastro-intestinal system	0.672	0.328
H50.9 Strabismus, unspecified	0.670	0.329
A49.8 Other bacterial infections of unspecified site	0.669	0.331
I12.9 Hypertensive renal disease without renal failure	0.667	0.333
N18.8 Other chronic renal failure	0.667	0.333
N18.1 Chronic kidney disease, stage 1	0.667	0.333
B15-B19 Viral hepatitis	0.667	0.333
W20-W49 Exposure to inanimate mechanical forces	0.665	0.335
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.663	0.337
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.663	0.337
J14 Pneumonia due to Haemophilus influenzae	0.662	0.338
I99 Other and unspecified disorders of circulatory system	0.662	0.338
I13 Hypertensive heart and renal disease	0.662	0.338
E27 Other disorders of adrenal gland	0.662	0.338
I11.0 Hypertensive heart disease with (congestive) heart failure	0.660	0.339
M47.1 Other spondylosis with myelopathy	0.660	0.340
A80-A89 Viral infections of the central nervous system	0.659	0.341
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.659	0.341
G50-G59 Nerve, nerve root and plexus disorders	0.658	0.342
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.658	0.342
Y49 Psychotropic drugs, not elsewhere classified	0.657	0.342
M42 Spinal osteochondrosis	0.657	0.343
M40 Kyphosis and lordosis	0.657	0.343
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.657	0.343
H69 Other disorders of Eustachian tube	0.656	0.344
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.656	0.344
I35 Nonrheumatic aortic valve disorders	0.656	0.344
Y00-Y09 Assault	0.655	0.345
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.655	0.345
I67.1 Cerebral aneurysm, nonruptured	0.655	0.345
I67.8 Other specified cerebrovascular diseases	0.655	0.345
O32.0 Maternal care for unstable lie	0.655	0.345
N03.9 Unspecified	0.654	0.346
E34 Other endocrine disorders	0.654	0.346
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.653	0.347
E40-E46 Malnutrition	0.651	0.349
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.651	0.349
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.649	0.351
W50-W64 Exposure to animate mechanical forces	0.649	0.351
R43 Disturbances of smell and taste	0.649	0.351
H46 Optic neuritis	0.648	0.352
R81 Glycosuria	0.647	0.353
O20-O29 Other maternal disorders predominantly related to pregnancy	0.647	0.353
H80-H83 Diseases of inner ear	0.647	0.353
H18 Other disorders of cornea	0.647	0.353
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.646	0.354
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.646	0.354
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.646	0.354
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.646	0.354
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.646	0.354
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.646	0.354
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.646	0.354
J93 Pneumothorax	0.646	0.354
J17 Pneumonia in diseases classified elsewhere	0.646	0.354
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.646	0.354
J12 Viral pneumonia, not elsewhere classified	0.646	0.354
J09 Influenza due to certain identified influenza virus	0.646	0.354
H49 Paralytic strabismus	0.646	0.354
R46.4 Slowness and poor responsiveness	0.645	0.355
G35-G37 Demyelinating diseases of the central nervous system	0.645	0.355
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.644	0.356
J98.8 Other specified respiratory disorders	0.643	0.357
R47 Speech disturbances, not elsewhere classified	0.643	0.357
G00-G09 Inflammatory diseases of the central nervous system	0.643	0.357
H53.9 Visual disturbance, unspecified	0.643	0.357
M47.80 Other spondylosis (Multiple sites in spine)	0.641	0.359
G80 Infantile cerebral palsy	0.641	0.359
G95.0 Syringomyelia and syringobulbia	0.640	0.360
R91 Abnormal findings on diagnostic imaging of lung	0.640	0.360
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.639	0.360
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.639	0.360
H15 Disorders of sclera	0.639	0.360
H53.4 Visual field defects	0.640	0.360
M47.89 Other spondylosis (Site unspecified)	0.639	0.361
N21.9 Calculus of lower urinary tract, unspecified	0.639	0.361
N21.8 Other lower urinary tract calculus	0.639	0.361
N21.1 Calculus in urethra	0.639	0.361
H20.0 Acute and subacute iridocyclitis	0.639	0.361
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.639	0.361
O32.9 Maternal care for malpresentation of foetus, unspecified	0.638	0.362
O32.6 Maternal care for compound presentation	0.638	0.362
O32.4 Maternal care for high head at term	0.638	0.362
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.638	0.362
J80 Adult respiratory distress syndrome	0.637	0.363
R33 Retention of urine	0.637	0.363
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.636	0.364
I95.8 Other hypotension	0.636	0.364
I95.0 Idiopathic hypotension	0.636	0.364
I78.1 Naevus, nonneoplastic	0.636	0.364
N70-N77 Inflammatory diseases of female pelvic organs	0.635	0.365
M47.99 Spondylosis, unspecified (Site unspecified)	0.635	0.365
J70 Respiratory conditions due to other external agents	0.634	0.365
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.634	0.365
J67 Hypersensitivity pneumonitis due to organic dust	0.634	0.365
J66 Airway disease due to specific organic dust	0.634	0.365
J63 Pneumoconiosis due to other inorganic dusts	0.634	0.365
J62 Pneumoconiosis due to dust containing silica	0.634	0.365
J65 Pneumoconiosis associated with tuberculosis	0.634	0.365
J64 Unspecified pneumoconiosis	0.634	0.365
J60 Coalworker's pneumoconiosis	0.634	0.365
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.634	0.366
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.634	0.366
M47.94 Spondylosis, unspecified (Thoracic region)	0.634	0.366
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.634	0.366
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.634	0.366
H47.2 Optic atrophy	0.634	0.366
J99.8 Respiratory disorders in other diseases classified elsewhere	0.634	0.366
M48.5 Collapsed vertebra, not elsewhere classified	0.634	0.366
A41.9 Septicaemia, unspecified	0.632	0.368
A48 Other bacterial diseases, not elsewhere classified	0.632	0.368
R40.0 Somnolence	0.632	0.368
O30 Multiple gestation	0.631	0.369
M89.9 Disorder of bone, unspecified	0.631	0.369
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.629	0.371
O97 Death from sequelae of direct obstetric causes	0.629	0.371
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.629	0.371
O95 Obstetric death of unspecified cause	0.629	0.371
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.629	0.371
H05.0 Acute inflammation of orbit	0.629	0.371
O34.1 Maternal care for tumour of corpus uteri	0.628	0.372
Y40 Systemic antibiotics	0.627	0.373
R80 Isolated proteinuria	0.626	0.374
G81 Hemiplegia	0.626	0.374
R46.8 Other symptoms and signs involving appearance and behaviour	0.625	0.375
J85 Abscess of lung and mediastinum	0.625	0.375
N05.8 Other	0.624	0.376
I52 Other heart disorders in diseases classified elsewhere	0.623	0.376
I48 Atrial fibrillation and flutter	0.623	0.376
I43 Cardiomyopathy in diseases classified elsewhere	0.623	0.376
I41 Myocarditis in diseases classified elsewhere	0.623	0.376
I40 Acute myocarditis	0.623	0.376
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.623	0.376
I37 Pulmonary valve disorders	0.623	0.376
I32 Pericarditis in diseases classified elsewhere	0.623	0.376
O40 Polyhydramnios	0.623	0.376
H51 Other disorders of binocular movement	0.622	0.378
I33.0 Acute and subacute infective endocarditis	0.622	0.378
A08 Viral and other specified intestinal infections	0.622	0.378
M82 Osteoporosis in diseases classified elsewhere	0.622	0.378
G70.0 Myasthenia gravis	0.622	0.378
H65 Nonsuppurative otitis media	0.622	0.378
G99.2 Myelopathy in diseases classified elsewhere	0.621	0.379
I25.5 Ischaemic cardiomyopathy	0.621	0.379
I42.9 Cardiomyopathy, unspecified	0.620	0.380
I71 Aortic aneurysm and dissection	0.619	0.380
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.619	0.381
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.619	0.381
I67.7 Cerebral arteritis, not elsewhere classified	0.618	0.382
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.618	0.382
I67.5 Moyamoya disease	0.618	0.382
I67.4 Hypertensive encephalopathy	0.618	0.382
I67.3 Progressive vascular leukoencephalopathy	0.618	0.382
I67.0 Dissection of cerebral arteries, nonruptured	0.618	0.382
M87 Osteonecrosis	0.618	0.382
O69 Labour and delivery complicated by umbilical cord complications	0.617	0.383
I22 Subsequent myocardial infarction	0.617	0.383
H25-H28 Disorders of lens	0.616	0.384
N48 Other disorders of penis	0.616	0.384
R45.1 Restlessness and agitation	0.616	0.384
Y35-Y36 Legal intervention and operations of war	0.615	0.385
Y10-Y34 Event of undetermined intent	0.615	0.385
X85-X99 Assault	0.615	0.385
X58-X59 Accidental exposure to other and unspecified factors	0.615	0.385
X30-X39 Exposure to forces of nature	0.615	0.385
X20-X29 Contact with venomous animals and plants	0.615	0.385
X10-X19 Contact with heat and hot substances	0.615	0.385
X00-X09 Exposure to smoke, fire and flames	0.615	0.385
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.615	0.385
W75-W84 Other accidental threats to breathing	0.615	0.385
W65-W74 Accidental drowning and submersion	0.615	0.385
V98-V99 Other and unspecified transport accidents	0.615	0.385
V95-V97 Air and space transport accidents	0.615	0.385
V90-V94 Water transport accidents	0.615	0.385
V70-V79 Bus occupant injured in transport accident	0.615	0.385
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.615	0.385
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.615	0.385
V40-V49 Car occupant injured in transport accident	0.615	0.385
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.615	0.385
V01-V09 Pedestrian injured in transport accident	0.615	0.385
M07 Psoriatic and enteropathic arthropathies	0.615	0.385
N02.9 Unspecified	0.615	0.385

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations