TreeWAS – Variant ID: rs1978029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E16.2 Hypoglycaemia, unspecified	0.000	0.001	0.999
E16 Other disorders of pancreatic internal secretion	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.997	0.003	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.004	0.996
E10.2 With renal complications	0.000	0.005	0.995
E50-E64 Other nutritional deficiencies	0.000	0.030	0.970
E10.4 With neurological complications	0.000	0.030	0.970
E10.5 With peripheral circulatory complications	0.000	0.053	0.947
E55 Vitamin D deficiency	0.000	0.064	0.936
E14 Unspecified diabetes mellitus	0.000	0.071	0.929
E55.9 Vitamin D deficiency, unspecified	0.000	0.089	0.911
L40 Psoriasis	0.909	0.091	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.092	0.908
G37 Other demyelinating diseases of central nervous system	0.000	0.114	0.886
D86.9 Sarcoidosis, unspecified	0.000	0.122	0.878
D86 Sarcoidosis	0.000	0.139	0.861
M06.9 Rheumatoid arthritis, unspecified	0.850	0.150	0.000
M06 Other rheumatoid arthritis	0.844	0.156	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.842	0.158	0.000
D86.0 Sarcoidosis of lung	0.000	0.164	0.836
L40.5 Arthropathic psoriasis	0.823	0.177	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.178	0.822
E14.3 With ophthalmic complications	0.000	0.182	0.818
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.183	0.817
E14.8 With unspecified complications	0.000	0.184	0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.803	0.197	0.000
L40.0 Psoriasis vulgaris	0.801	0.199	0.000
M06.3 Rheumatoid nodule	0.798	0.202	0.000
E53 Deficiency of other B group vitamins	0.000	0.202	0.798
E10.7 With multiple complications	0.000	0.210	0.790
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.782	0.218	0.000
E14.6 With other specified complications	0.000	0.221	0.779
M06.0 Seronegative rheumatoid arthritis	0.775	0.225	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.772	0.228	0.000
M05 Seropositive rheumatoid arthritis	0.772	0.228	0.000
M05-M14 Inflammatory polyarthropathies	0.771	0.229	0.000
E40-E46 Malnutrition	0.000	0.230	0.770
E10.0 With coma	0.000	0.232	0.768
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.238	0.762
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.244	0.756
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.749	0.251	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.256	0.743
E10.8 With unspecified complications	0.000	0.264	0.735
E10.6 With other specified complications	0.000	0.270	0.730
D86.8 Sarcoidosis of other and combined sites	0.000	0.276	0.724
E14.2 Withrenal complications	0.000	0.279	0.721
E51 Thiamine deficiency	0.000	0.279	0.721
E61 Deficiency of other nutrient elements	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E15 Nondiabetic hypoglycaemic coma	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.716
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.284	0.716
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.284	0.716
E16.4 Abnormal secretion of gastrin	0.000	0.284	0.716
E16.3 Increased secretion of glucagon	0.000	0.284	0.716
K90 Intestinal malabsorption	0.000	0.303	0.697
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.304	0.695
E63 Other nutritional deficiencies	0.000	0.304	0.695
E50 Vitamin A deficiency	0.000	0.304	0.695
E60 Dietary zinc deficiency	0.000	0.304	0.695
E59 Dietary selenium deficiency	0.000	0.304	0.695
E54 Ascorbic acid deficiency	0.000	0.304	0.695
E52 Niacin deficiency [pellagra]	0.000	0.304	0.695
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.693	0.307	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.308	0.692
M06.98 Rheumatoid arthritis, unspecified (Other)	0.692	0.308	0.000
E56 Other vitamin deficiencies	0.000	0.312	0.687
M06.34 Rheumatoid nodule (Hand)	0.687	0.313	0.000
G36 Other acute disseminated demyelination	0.000	0.316	0.683
M06.32 Rheumatoid nodule (Upper arm)	0.680	0.320	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.321	0.679
D80-D89 Certain disorders involving the immune mechanism	0.000	0.321	0.679
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.672	0.328	0.000
E55.0 Rickets, active	0.000	0.329	0.671
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.669	0.331	0.000
L40.1 Generalised pustular psoriasis	0.667	0.333	0.000
E14.7 With multiple complications	0.000	0.334	0.666
E14.0 With coma	0.000	0.334	0.666
E20-E35 Disorders of other endocrine glands	0.000	0.336	0.664
L40.4 Guttate psoriasis	0.662	0.337	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.339	0.661
L40.3 Pustulosis palmaris et plantaris	0.661	0.339	0.000
E27 Other disorders of adrenal gland	0.000	0.339	0.660
E53.9 Vitamin B deficiency, unspecified	0.000	0.346	0.654
E58 Dietary calcium deficiency	0.000	0.347	0.653
L40.2 Acrodermatitis continua	0.652	0.348	0.000
E14.5 With peripheral circulatory complications	0.000	0.354	0.646
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.355	0.645
E14.9 Without complications	0.000	0.357	0.643
M06.33 Rheumatoid nodule (Forearm)	0.641	0.359	0.000
E13 Other specified diabetes mellitus	0.000	0.360	0.640
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.639	0.361	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.637	0.363	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.365	0.635
G37.4 Subacute necrotising myelitis	0.000	0.365	0.635
G37.2 Central pontine myelinolysis	0.000	0.365	0.635
G37.1 Central demyelination of corpus callosum	0.000	0.365	0.635
G37.0 Diffuse sclerosis	0.000	0.365	0.635
K90.9 Intestinal malabsorption, unspecified	0.000	0.367	0.633
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.377	0.623
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.621	0.379	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.616	0.384	0.000
E61.2 Magnesium deficiency	0.000	0.389	0.610
M06.1 Adult-onset Still's disease	0.607	0.393	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.607	0.393	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.605	0.395	0.000
M06.2 Rheumatoid bursitis	0.605	0.395	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.395	0.605
L40.8 Other psoriasis	0.604	0.395	0.000
M05.1 Rheumatoid lung disease	0.604	0.396	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.396	0.604
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.604	0.396	0.000
M05.8 Other seropositive rheumatoid arthritis	0.603	0.397	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.602	0.398	0.000
E14.1 With ketoacidosis	0.000	0.398	0.602
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.602	0.398	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.599	0.401	0.000
M06.4 Inflammatory polyarthropathy	0.599	0.401	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.402	0.598
M14 Arthropathies in other diseases classified elsewhere	0.597	0.403	0.000
E06 Thyroiditis	0.000	0.403	0.597
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.587	0.413	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.584	0.416	0.000
M08 Juvenile arthritis	0.579	0.421	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.578	0.422	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.423	0.577
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.424	0.576
E07 Other disorders of thyroid	0.000	0.427	0.573
M06.39 Rheumatoid nodule (Site unspecified)	0.572	0.428	0.000
M06.38 Rheumatoid nodule (Other)	0.572	0.428	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.572	0.428	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.572	0.428	0.000
E53.1 Pyridoxine deficiency	0.000	0.428	0.572
E53.0 Riboflavin deficiency	0.000	0.428	0.572
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.570	0.430	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.562	0.438	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.559	0.441	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.556	0.444	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.556	0.444	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.556	0.444	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.556	0.444	0.000
E27.2 Addisonian crisis	0.000	0.446	0.554
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.554	0.446	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.553	0.447	0.000
M05.0 Felty's syndrome	0.553	0.447	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.553	0.447	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.448	0.552
E45 Retarded development following protein-energy malnutrition	0.000	0.448	0.552
E43 Unspecified severe protein-energy malnutrition	0.000	0.448	0.552
E42 Marasmic kwashiorkor	0.000	0.448	0.552
E41 Nutritional marasmus	0.000	0.448	0.552
E40 Kwashiorkor	0.000	0.448	0.552
E04 Other non-toxic goitre	0.000	0.450	0.550
M06.8 Other specified rheumatoid arthritis	0.546	0.454	0.000
E51.2 Wernicke's encephalopathy	0.000	0.457	0.543
E05.8 Other thyrotoxicosis	0.000	0.461	0.539
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.461	0.539
M11 Other crystal arthropathies	0.538	0.462	0.000
D86.3 Sarcoidosis of skin	0.000	0.471	0.529
D82 Immunodeficiency associated with other major defects	0.000	0.473	0.526
E20 Hypoparathyroidism	0.000	0.474	0.525
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.524	0.475	0.000
M05.2 Rheumatoid vasculitis	0.524	0.476	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.478	0.522
E51.9 Thiamine deficiency, unspecified	0.000	0.483	0.517
E51.8 Other manifestations of thiamine deficiency	0.000	0.483	0.517
E51.1 Beriberi	0.000	0.483	0.517
E61.9 Deficiency of nutrient element, unspecified	0.000	0.486	0.514
E61.8 Deficiency of other specified nutrient elements	0.000	0.486	0.514
E61.7 Deficiency of multiple nutrient elements	0.000	0.486	0.514
E61.6 Vanadium deficiency	0.000	0.486	0.514
E61.5 Molybdenum deficiency	0.000	0.486	0.514
E61.4 Chromium deficiency	0.000	0.486	0.514
E61.3 Manganese deficiency	0.000	0.486	0.514
E61.0 Copper deficiency	0.000	0.486	0.514
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E27.8 Other specified disorders of adrenal gland	0.000	0.487	0.513
K90.3 Pancreatic steatorrhoea	0.000	0.500	0.499
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.500	0.499
K90.1 Tropical sprue	0.000	0.500	0.499
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.501	0.499
E50.9 Vitamin A deficiency, unspecified	0.000	0.501	0.499
E50.8 Other manifestations of vitamin A deficiency	0.000	0.501	0.499
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.501	0.499
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.501	0.499
E50.5 Vitamin A deficiency with night blindness	0.000	0.501	0.499
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.501	0.499
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.501	0.499
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.501	0.499
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.501	0.499
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.501	0.499
E63.9 Nutritional deficiency, unspecified	0.000	0.501	0.499
E63.8 Other specified nutritional deficiencies	0.000	0.501	0.499
E63.1 Imbalance of constituents of food intake	0.000	0.501	0.499
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.501	0.499
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.501	0.499
E64.8 Sequelae of other nutritional deficiencies	0.000	0.501	0.499
E64.3 Sequelae of rickets	0.000	0.501	0.499
E64.2 Sequelae of vitamin C deficiency	0.000	0.501	0.499
E64.1 Sequelae of vitamin A deficiency	0.000	0.501	0.499
E64.0 Sequelae of protein-energy malnutrition	0.000	0.501	0.499
E14.4 With neurological complications	0.000	0.501	0.498
E56.9 Vitamin deficiency, unspecified	0.000	0.507	0.493
E56.8 Deficiency of other vitamins	0.000	0.507	0.493
E56.0 Deficiency of vitamin E	0.000	0.507	0.493
M14.6 Neuropathic arthropathy	0.490	0.509	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.510	0.490
G36.8 Other specified acute disseminated demyelination	0.000	0.510	0.490
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.510	0.490
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.489	0.511	0.000
E31 Polyglandular dysfunction	0.000	0.512	0.488
D81 Combined immunodeficiencies	0.000	0.513	0.486
E56.1 Deficiency of vitamin K	0.000	0.515	0.485
M05.19 Rheumatoid lung disease (Site unspecified)	0.484	0.516	0.000
M07 Psoriatic and enteropathic arthropathies	0.484	0.516	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.483	0.517	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.523	0.476
E32 Diseases of thymus	0.000	0.523	0.476
E30 Disorders of puberty, not elsewhere classified	0.000	0.523	0.476
L40-L45 Papulosquamous disorders	0.469	0.524	0.007
E27.5 Adrenomedullary hyperfunction	0.000	0.526	0.474
E27.0 Other adrenocortical overactivity	0.000	0.526	0.474
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.529	0.471
D80 Immunodeficiency with predominantly antibody defects	0.000	0.532	0.468
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.467	0.532	0.000
E34 Other endocrine disorders	0.000	0.532	0.467
E16.1 Other hypoglycaemia	0.001	0.535	0.465
D89.3 Immune reconstitution syndrome	0.000	0.537	0.463
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.460	0.540	0.000
E13.8 With unspecified complications	0.000	0.541	0.459
E13.7 With multiple complications	0.000	0.541	0.459
E13.6 With other specified complications	0.000	0.541	0.459
E13.5 With peripheral circulatory complications	0.000	0.541	0.459
E13.4 With neurological complications	0.000	0.541	0.459
E13.2 With renal complications	0.000	0.541	0.459
E13.1 With ketoacidosis	0.000	0.541	0.459
E13.0 With coma	0.000	0.541	0.459
D83 Common variable immunodeficiency	0.000	0.542	0.458
M12 Other specific arthropathies	0.456	0.543	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.455	0.545	0.000
E06.5 Other chronic thyroiditis	0.000	0.546	0.454
E04.2 Non-toxic multinodular goitre	0.000	0.549	0.451
M06.46 Inflammatory polyarthropathy (Lower leg)	0.450	0.550	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.450	0.550	0.000
E28 Ovarian dysfunction	0.000	0.554	0.446
K90.8 Other intestinal malabsorption	0.000	0.557	0.442
M08.0 Juvenile rheumatoid arthritis	0.441	0.559	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.438	0.562	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.435	0.564	0.000
M06.18 Adult-onset Still's disease (Other)	0.435	0.564	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.435	0.564	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.435	0.564	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.435	0.564	0.000
M06.14 Adult-onset Still's disease (Hand)	0.435	0.564	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.435	0.564	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.435	0.564	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.435	0.564	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.434	0.566	0.000
M06.28 Rheumatoid bursitis (Other)	0.434	0.566	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.434	0.566	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.434	0.566	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.434	0.566	0.000
M06.24 Rheumatoid bursitis (Hand)	0.434	0.566	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.434	0.566	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.434	0.566	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.434	0.566	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.434	0.566	0.000
M05.18 Rheumatoid lung disease (Other)	0.433	0.567	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.433	0.567	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.433	0.567	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.433	0.567	0.000
M05.14 Rheumatoid lung disease (Hand)	0.433	0.567	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.433	0.567	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.433	0.567	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.433	0.567	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.433	0.567	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.432	0.568	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.432	0.568	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.432	0.568	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.432	0.568	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.432	0.568	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.432	0.568	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.432	0.568	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.432	0.568	0.000
E13.9 Without complications	0.000	0.570	0.430
M06.48 Inflammatory polyarthropathy (Other)	0.429	0.571	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.429	0.571	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.429	0.571	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.429	0.571	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.429	0.571	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.429	0.571	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.429	0.571	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.428	0.572	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.428	0.572	0.000
M14.4 Arthropathy in amyloidosis	0.428	0.572	0.000
M14.3 Lipoid dermatoarthritis	0.428	0.572	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.428	0.572	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.428	0.572	0.000
E06.4 Drug-induced thyroiditis	0.000	0.572	0.428
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.572	0.428
E06.0 Acute thyroiditis	0.000	0.572	0.428
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.572	0.428
E04.0 Non-toxic diffuse goitre	0.000	0.573	0.427
E06.1 Subacute thyroiditis	0.000	0.573	0.427
E20.9 Hypoparathyroidism, unspecified	0.000	0.574	0.426
E06.9 Thyroiditis, unspecified	0.000	0.577	0.423
M11.9 Crystal arthropathy, unspecified	0.421	0.579	0.000
D82.1 Di George's syndrome	0.000	0.582	0.418
E13.3 With ophthalmic complications	0.000	0.583	0.417
M08.2 Juvenile arthritis with systemic onset	0.416	0.584	0.000
M08.9 Juvenile arthritis, unspecified	0.415	0.584	0.000
M08.8 Other juvenile arthritis	0.415	0.584	0.000
M08.4 Pauciarticular juvenile arthritis	0.415	0.584	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.415	0.584	0.000
M08.1 Juvenile ankylosing spondylitis	0.415	0.584	0.000
E07.1 Dyshormogenetic goitre	0.000	0.589	0.411
E07.0 Hypersecretion of calcitonin	0.000	0.589	0.411
E26 Hyperaldosteronism	0.000	0.596	0.404
D84 Other immunodeficiencies	0.000	0.596	0.404
E25 Adrenogenital disorders	0.000	0.600	0.400
M14.2 Diabetic arthropathy	0.399	0.600	0.000
E34.8 Other specified endocrine disorders	0.000	0.601	0.399
E24 Cushing's syndrome	0.000	0.602	0.398
M05.09 Felty's syndrome (Site unspecified)	0.397	0.603	0.000
M05.08 Felty's syndrome (Other)	0.397	0.603	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.397	0.603	0.000
M05.06 Felty's syndrome (Lower leg)	0.397	0.603	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.397	0.603	0.000
M05.04 Felty's syndrome (Hand)	0.397	0.603	0.000
M05.03 Felty's syndrome (Forearm)	0.397	0.603	0.000
M05.02 Felty's syndrome (Upper arm)	0.397	0.603	0.000
M05.01 Felty's syndrome (Shoulder region)	0.397	0.603	0.000
M05.00 Felty's syndrome (Multiple sites)	0.397	0.603	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.397	0.603	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.397	0.603	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.397	0.603	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.397	0.603	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.397	0.603	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.397	0.603	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.397	0.603	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.397	0.603	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.397	0.603	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.397	0.603	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.396	0.603	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.396	0.603	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.396	0.603	0.000
M09.0 Juvenile arthritis in psoriasis	0.396	0.603	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.604	0.396
E44.0 Moderate protein-energy malnutrition	0.000	0.604	0.396
L42 Pityriasis rosea	0.391	0.605	0.004
E04.8 Other specified non-toxic goitre	0.000	0.605	0.394
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.394	0.606	0.000
M13 Other arthritis	0.393	0.607	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.391	0.609	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.391	0.609	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.391	0.609	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.391	0.609	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.391	0.609	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.391	0.609	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.391	0.609	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.391	0.609	0.000
E07.8 Other specified disorders of thyroid	0.000	0.610	0.390
D89.1 Cryoglobulinaemia	0.000	0.612	0.388
M11.1 Familial chondrocalcinosis	0.386	0.614	0.000
M11.0 Hydroxyapatite deposition disease	0.386	0.614	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.622	0.377
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.622	0.377
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.622	0.377
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.622	0.377
D82.2 Immunodeficiency with short-limbed stature	0.000	0.622	0.377
D82.0 Wiskott-Aldrich syndrome	0.000	0.622	0.377
E20.8 Other hypoparathyroidism	0.000	0.623	0.377
E20.1 Pseudohypoparathyroidism	0.000	0.623	0.377
E20.0 Idiopathic hypoparathyroidism	0.000	0.623	0.377
M05.28 Rheumatoid vasculitis (Other)	0.376	0.624	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.376	0.624	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.376	0.624	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.376	0.624	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.376	0.624	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.376	0.624	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.376	0.624	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.376	0.624	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.625	0.375
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.625	0.375
E61.1 Iron deficiency	0.000	0.628	0.372
M11.8 Other specified crystal arthropathies	0.367	0.633	0.000
C21.0 Anus, unspecified	0.366	0.634	0.000
L44 Other papulosquamous disorders	0.358	0.637	0.005
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.363	0.637	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.362	0.638	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.362	0.638	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.638	0.362
E28.3 Primary ovarian failure	0.000	0.641	0.359
C21.1 Anal canal	0.356	0.644	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.645	0.355
C21 Malignant neoplasm of anus and anal canal	0.355	0.645	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.650	0.350
E31.8 Other polyglandular dysfunction	0.000	0.650	0.350
E31.1 Polyglandular hyperfunction	0.000	0.650	0.350
D81.9 Combined immunodeficiency, unspecified	0.000	0.651	0.349
D81.8 Other combined immunodeficiencies	0.000	0.651	0.349
D81.7 Major histocompatibility complex class II deficiency	0.000	0.651	0.349
D81.6 Major histocompatibility complex class I deficiency	0.000	0.651	0.349
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.651	0.349
D81.4 Nezelof's syndrome	0.000	0.651	0.349
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.651	0.349
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.651	0.349
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.651	0.349
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.651	0.349
M07.5 Arthropathy in ulcerative colitis	0.347	0.653	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.347	0.653	0.000
M07.2 Psoriatic spondylitis	0.347	0.653	0.000
M07.1 Arthritis mutilans	0.347	0.653	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.347	0.653	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.653	0.347
M11.2 Other chondrocalcinosis	0.345	0.655	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.342	0.657	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.658	0.342
E30.8 Other disorders of puberty	0.000	0.658	0.342
E30.1 Precocious puberty	0.000	0.658	0.342
E30.0 Delayed puberty	0.000	0.658	0.342
E32.9 Disease of thymus, unspecified	0.000	0.658	0.342
E32.8 Other diseases of thymus	0.000	0.658	0.342
E32.1 Abscess of thymus	0.000	0.658	0.342
E32.0 Persistent hyperplasia of thymus	0.000	0.658	0.342
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.658	0.342
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.658	0.342
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.658	0.342
L41 Parapsoriasis	0.336	0.659	0.005
L45 Papulosquamous disorders in diseases classified elsewhere	0.336	0.659	0.005
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.662	0.338
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.336	0.663	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.664	0.336
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.664	0.336
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.664	0.336
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.664	0.336
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.664	0.336
E34.5 Androgen resistance syndrome	0.000	0.665	0.335
E34.4 Constitutional tall stature	0.000	0.665	0.335
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.665	0.335
E34.1 Other hypersecretion of intestinal hormones	0.000	0.665	0.335
M07.6 Other enteropathic arthropathies	0.330	0.670	0.000
E34.0 Carcinoid syndrome	0.000	0.670	0.329
D83.8 Other common variable immunodeficiencies	0.000	0.672	0.328
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.672	0.328
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.672	0.328
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.672	0.328
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.328	0.672	0.000
M12.4 Intermittent hydrarthrosis	0.327	0.672	0.000
M12.1 Kaschin-Beck disease	0.327	0.672	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.327	0.672	0.000
E29 Testicular dysfunction	0.000	0.676	0.324
E34.3 Short stature, not elsewhere classified	0.000	0.677	0.322
M12.5 Traumatic arthropathy	0.321	0.679	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.680	0.320
E28.8 Other ovarian dysfunction	0.000	0.680	0.320
E28.1 Androgen excess	0.000	0.680	0.320
E28.0 Oestrogen excess	0.000	0.680	0.320
M13.1 Monoarthritis, not elsewhere classified	0.318	0.682	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.316	0.683	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.316	0.683	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.316	0.683	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.316	0.683	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.316	0.683	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.316	0.683	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.316	0.683	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.316	0.683	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations