TreeWAS – Variant ID: rs1982346

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I34.0 Mitral (valve) insufficiency	0.031	0.969	0.000
I34 Nonrheumatic mitral valve disorders	0.028	0.972	0.000
I34.1 Mitral (valve) prolapse	0.027	0.973	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.978	0.022
I34.2 Nonrheumatic mitral (valve) stenosis	0.021	0.979	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.020	0.980	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.020	0.980	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.981	0.019
I35 Nonrheumatic aortic valve disorders	0.018	0.982	0.000
I35.0 Aortic (valve) stenosis	0.018	0.982	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.017	0.983	0.000
I31.3 Pericardial effusion (noninflammatory)	0.017	0.983	0.000
I30-I52 Other forms of heart disease	0.016	0.984	0.000
I31 Other diseases of pericardium	0.016	0.984	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.984	0.016
I35.9 Aortic valve disorder, unspecified	0.014	0.985	0.000
I42 Cardiomyopathy	0.014	0.986	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.986	0.014
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.014
I42.1 Obstructive hypertrophic cardiomyopathy	0.014	0.986	0.000
I35.8 Other aortic valve disorders	0.013	0.986	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.986	0.013
I51 Complications and ill-defined descriptions of heart disease	0.013	0.987	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.987	0.013
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.987	0.013
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.013
I37 Pulmonary valve disorders	0.013	0.987	0.000
I42.2 Other hypertrophic cardiomyopathy	0.013	0.987	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.013	0.987	0.000
I49 Other cardiac arrhythmias	0.013	0.987	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.987	0.012
I35.1 Aortic (valve) insufficiency	0.012	0.988	0.000
R52.1 Chronic intractable pain	0.000	0.988	0.012
C78.7 Secondary malignant neoplasm of liver	0.000	0.988	0.012
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.012	0.988	0.000
I52 Other heart disorders in diseases classified elsewhere	0.012	0.988	0.000
I48 Atrial fibrillation and flutter	0.012	0.988	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.012	0.988	0.000
I41 Myocarditis in diseases classified elsewhere	0.012	0.988	0.000
I40 Acute myocarditis	0.012	0.988	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I32 Pericarditis in diseases classified elsewhere	0.012	0.988	0.000
I36 Nonrheumatic tricuspid valve disorders	0.012	0.988	0.000
I31.8 Other specified diseases of pericardium	0.012	0.988	0.000
I31.2 Haemopericardium, not elsewhere classified	0.012	0.988	0.000
I31.1 Chronic constrictive pericarditis	0.012	0.988	0.000
I31.0 Chronic adhesive pericarditis	0.012	0.988	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.988	0.012
I49.8 Other specified cardiac arrhythmias	0.012	0.988	0.000
I49.3 Ventricular premature depolarisation	0.012	0.988	0.000
I45 Other conduction disorders	0.011	0.989	0.000
I42.8 Other cardiomyopathies	0.011	0.989	0.000
I38 Endocarditis, valve unspecified	0.011	0.989	0.000
I51.0 Cardiac septal defect, acquired	0.011	0.989	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.011	0.989	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.010	0.989	0.000
I42.5 Other restrictive cardiomyopathy	0.010	0.989	0.000
I42.4 Endocardial fibroelastosis	0.010	0.989	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.010	0.989	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.990	0.010
I49.1 Atrial premature depolarisation	0.010	0.990	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.990	0.010
I37.1 Pulmonary valve insufficiency	0.010	0.990	0.000
I33 Acute and subacute endocarditis	0.010	0.990	0.000
I51.5 Myocardial degeneration	0.010	0.990	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.010	0.990	0.000
I31.9 Disease of pericardium, unspecified	0.010	0.990	0.000
I51.8 Other ill-defined heart diseases	0.010	0.990	0.000
I49.0 Ventricular fibrillation and flutter	0.009	0.990	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.991	0.009
I30 Acute pericarditis	0.009	0.991	0.000
I37.9 Pulmonary valve disorder, unspecified	0.009	0.991	0.000
I37.8 Other pulmonary valve disorders	0.009	0.991	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.009	0.991	0.000
I37.0 Pulmonary valve stenosis	0.009	0.991	0.000
I49.2 Junctional premature depolarisation	0.009	0.991	0.000
I51.6 Cardiovascular disease, unspecified	0.009	0.991	0.000
I45.4 Nonspecific intraventricular block	0.009	0.991	0.000
I45.3 Trifascicular block	0.009	0.991	0.000
I42.6 Alcoholic cardiomyopathy	0.009	0.991	0.000
I45.8 Other specified conduction disorders	0.009	0.991	0.000
I51.9 Heart disease, unspecified	0.009	0.991	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.009	0.991	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.009	0.991	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.009	0.991	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.009	0.991	0.000
I40.9 Acute myocarditis, unspecified	0.009	0.991	0.000
I40.8 Other acute myocarditis	0.009	0.991	0.000
I40.1 Isolated myocarditis	0.009	0.991	0.000
I40.0 Infective myocarditis	0.009	0.991	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.009	0.991	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.009	0.991	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.009	0.991	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.009	0.991	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.009	0.991	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.009	0.991	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.009	0.991	0.000
I48.4 Atypical atrial flutter	0.009	0.991	0.000
I48.3 Typical atrial flutter	0.009	0.991	0.000
I48.2 Chronic atrial fibrillation	0.009	0.991	0.000
I48.1 Persistent atrial fibrillation	0.009	0.991	0.000
I48.0 Paroxysmal atrial fibrillation	0.009	0.991	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.009	0.991	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.009	0.991	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.009	0.991	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.009	0.991	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.009	0.991	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.009	0.991	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.009	0.991	0.000
I45.6 Preexcitation syndrome	0.009	0.991	0.000
I45.5 Other specified heart block	0.009	0.991	0.000
I51.4 Myocarditis, unspecified	0.008	0.992	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.992	0.008
N81.1 Cystocele	0.000	0.992	0.008
I47 Paroxysmal tachycardia	0.008	0.992	0.000
I45.0 Right fascicular block	0.008	0.992	0.000
I51.7 Cardiomegaly	0.008	0.992	0.000
R52 Pain, not elsewhere classified	0.000	0.992	0.008
I45.9 Conduction disorder, unspecified	0.008	0.992	0.000
I42.9 Cardiomyopathy, unspecified	0.008	0.992	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.992	0.008
I33.9 Acute endocarditis, unspecified	0.007	0.993	0.000
I45.2 Bifascicular block	0.007	0.993	0.000
I42.0 Dilated cardiomyopathy	0.007	0.993	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.993	0.007
R52.2 Other chronic pain	0.000	0.993	0.007
C78.2 Secondary malignant neoplasm of pleura	0.000	0.993	0.007
I47.9 Paroxysmal tachycardia, unspecified	0.007	0.993	0.000
I30.8 Other forms of acute pericarditis	0.007	0.993	0.000
I30.1 Infective pericarditis	0.007	0.993	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.007	0.993	0.000
I49.5 Sick sinus syndrome	0.007	0.993	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.993	0.007
I46 Cardiac arrest	0.007	0.993	0.000
Z57 Occupational exposure to risk-factors	0.007	0.993	0.000
R52.0 Acute pain	0.000	0.994	0.006
I47.0 Reentry ventricular arrhythmia	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
I49.4 Other and unspecified premature depolarisation	0.005	0.994	0.000
R63.0 Anorexia	0.000	0.995	0.005
I33.0 Acute and subacute infective endocarditis	0.005	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O97 Death from sequelae of direct obstetric causes	0.000	0.995	0.005
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.995	0.005
O95 Obstetric death of unspecified cause	0.000	0.995	0.005
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.995	0.005
I46.1 Sudden cardiac death, so described	0.005	0.995	0.000
R52.9 Pain, unspecified	0.000	0.995	0.005
Z57.9 Occupational exposure to unspecified risk-factor	0.005	0.995	0.000
Z57.8 Occupational exposure to other risk-factors	0.005	0.995	0.000
Z57.7 Occupational exposure to vibration	0.005	0.995	0.000
Z57.6 Occupational exposure to extreme temperature	0.005	0.995	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.005	0.995	0.000
Z57.1 Occupational exposure to radiation	0.005	0.995	0.000
Z57.0 Occupational exposure to noise	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
I30.9 Acute pericarditis, unspecified	0.004	0.995	0.001
R63 Symptoms and signs concerning food and fluid intake	0.000	0.996	0.004
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.996	0.004
Z57.3 Occupational exposure to other air contaminants	0.004	0.996	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.996	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
R60.0 Localised oedema	0.000	0.996	0.004
O96.9 Death from unspecified obstetric cause	0.000	0.996	0.004
O96.1 Death from indirect obstetric cause	0.000	0.996	0.004
O96.0 Death from direct obstetric cause	0.000	0.996	0.004
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.996	0.004
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.996	0.004
O97.0 Death from sequelae of direct obstetric cause	0.000	0.996	0.004
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
F41 Other anxiety disorders	0.000	0.996	0.004
I44 Atrioventricular and left bundle-branch block	0.004	0.996	0.000
I49.9 Cardiac arrhythmia, unspecified	0.004	0.996	0.000
R63.1 Polydipsia	0.000	0.996	0.004
R63.5 Abnormal weight gain	0.000	0.996	0.003
S81.8 Open wound of other parts of lower leg	0.000	0.996	0.004
O20.0 Threatened abortion	0.000	0.996	0.004
R63.6 Insufficient intake of food and water due to self neglect	0.000	0.997	0.003
R63.3 Feeding difficulties and mismanagement	0.000	0.997	0.003
R63.2 Polyphagia	0.000	0.997	0.003
M25.46 Effusion of joint (Lower leg)	0.000	0.997	0.003
R60 Oedema, not elsewhere classified	0.000	0.997	0.003
I46.0 Cardiac arrest with successful resuscitation	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
I44.4 Left anterior fascicular block	0.003	0.997	0.000
R56.8 Other and unspecified convulsions	0.000	0.997	0.003
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
I47.2 Ventricular tachycardia	0.003	0.997	0.000
F41.8 Other specified anxiety disorders	0.000	0.997	0.003
F41.3 Other mixed anxiety disorders	0.000	0.997	0.003
R60.9 Oedema, unspecified	0.000	0.997	0.003
I44.5 Left posterior fascicular block	0.003	0.997	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.997	0.003
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
R56 Convulsions, not elsewhere classified	0.000	0.997	0.003
I44.0 Atrioventricular block, first degree	0.003	0.997	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.997	0.003
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
I44.3 Other and unspecified atrioventricular block	0.003	0.997	0.000
R54 Senility	0.000	0.997	0.003
R60.1 Generalised oedema	0.000	0.997	0.003
R61 Hyperhidrosis	0.000	0.997	0.003
S81.0 Open wound of knee	0.000	0.997	0.003
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.997	0.000
Y54.7 Agents affecting calcification	0.002	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.997	0.000
Y54.0 Mineralocorticoids	0.002	0.997	0.000
I44.6 Other and unspecified fascicular block	0.002	0.997	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.002	0.997	0.000
S81 Open wound of lower leg	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.002	0.997	0.000
R50-R69 General symptoms and signs	0.000	0.997	0.003
I50 Heart failure	0.002	0.997	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
R63.4 Abnormal weight loss	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.002	0.998	0.000
R56.0 Febrile convulsions	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
Y48.3 Local anaesthetics	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I80 Phlebitis and thrombophlebitis	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.000	0.998	0.002
H40.0 Glaucoma suspect	0.000	0.998	0.002
K56.2 Volvulus	0.000	0.998	0.002
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.998	0.002
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
F43.0 Acute stress reaction	0.000	0.998	0.002
R44.1 Visual hallucinations	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
R61.1 Generalised hyperhidrosis	0.000	0.998	0.002
R61.0 Localised hyperhidrosis	0.000	0.998	0.002
F43 Reaction to severe stress, and adjustment disorders	0.000	0.998	0.002
Y45.1 Salicylates	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
F41.1 Generalised anxiety disorder	0.000	0.998	0.002
F43.1 Posttraumatic stress disorder	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.000	0.998	0.002
R62 Lack of expected normal physiological development	0.000	0.998	0.002
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.000	0.998	0.002
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
F40 Phobic anxiety disorders	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.002	0.998	0.000
X62.9 Unspecified place	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
R27.0 Ataxia, unspecified	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
F48 Other neurotic disorders	0.000	0.998	0.002
R57 Shock, not elsewhere classified	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
K56.6 Other and unspecified intestinal obstruction	0.000	0.998	0.002
Y48.5 Therapeutic gases	0.002	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
Y48.1 Parenteral anaesthetics	0.002	0.998	0.000
Y48.0 Inhaled anaesthetics	0.002	0.998	0.000
Z42 Follow-up care involving plastic surgery	0.002	0.998	0.000
Z59 Problems related to housing and economic circumstances	0.002	0.998	0.000
I95.2 Hypotension due to drugs	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
F42 Obsessive-compulsive disorder	0.000	0.998	0.002
R64 Cachexia	0.000	0.998	0.002
R58 Haemorrhage, not elsewhere classified	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
F43.9 Reaction to severe stress, unspecified	0.000	0.998	0.002
F43.8 Other reactions to severe stress	0.000	0.998	0.002
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
F44 Dissociative [conversion] disorders	0.000	0.998	0.002
R68 Other general symptoms and signs	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
F45.4 Persistent somatoform pain disorder	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
F45.1 Undifferentiated somatoform disorder	0.000	0.998	0.002
F45.0 Somatisation disorder	0.000	0.998	0.002
R62.9 Lack of expected normal physiological development, unspecified	0.000	0.998	0.002
R62.8 Other lack of expected normal physiological development	0.000	0.998	0.002
R62.0 Delayed milestone	0.000	0.998	0.002
R65.9 Systemic Inflammatory Response Syndrome, unspecified	0.000	0.998	0.002
R65.3 Systemic Inflammatory Response Syndrome of non-infectious origin with organ failure	0.000	0.998	0.002
R65.2 Systemic Inflammatory Response Syndrome of non-infectious origin without organ failure	0.000	0.998	0.002
R65.1 Systemic Inflammatory Response Syndrome of infectious origin with organ failure	0.000	0.998	0.002
R65.0 Systemic Inflammatory Response Syndrome of infectious origin without organ failure	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
Y46.4 Iminostilbenes	0.002	0.998	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Z59.0 Homelessness	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.998	0.002
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Z63 Other problems related to primary support group, including family circumstances	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.000	0.998	0.002
F40.1 Social phobias	0.000	0.998	0.002
F40.0 Agoraphobia	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
Y46.2 Hydantoin derivatives	0.002	0.998	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.002	0.998	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.998	0.002
Y46.8 Antispasticity drugs	0.001	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.001	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.998	0.000
Y46.5 Valproic acid	0.001	0.998	0.000
Y46.3 Deoxybarbiturates	0.001	0.998	0.000
Y46.1 Oxazolidinediones	0.001	0.998	0.000
Y46.0 Succinimides	0.001	0.998	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
K56.4 Other impaction of intestine	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
Z58 Problems related to physical environment	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.001	0.998	0.000
Z52.4 Kidney donor	0.002	0.998	0.000
F48.9 Neurotic disorder, unspecified	0.000	0.998	0.001
F48.8 Other specified neurotic disorders	0.000	0.998	0.001
F48.1 Depersonalisation-derealisation syndrome	0.000	0.998	0.001
K56.1 Intussusception	0.000	0.998	0.002
R57.9 Shock, unspecified	0.000	0.998	0.001
R57.8 Other shock	0.000	0.998	0.001
R57.1 Hypovolaemic shock	0.000	0.998	0.001
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.002	0.998	0.000
Y43 Primarily systemic agents	0.002	0.998	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.001	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.001	0.998	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.001	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.001	0.998	0.000
Z59.6 Low income	0.001	0.998	0.000
Z59.5 Extreme poverty	0.001	0.998	0.000
Z59.4 Lack of adequate food	0.001	0.998	0.000
Z59.3 Problems related to living in residential institution	0.001	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.001	0.998	0.000
Z59.1 Inadequate housing	0.001	0.998	0.000
S80 Superficial injury of lower leg	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.001
F42.8 Other obsessive-compulsive disorders	0.000	0.998	0.001
F42.2 Mixed obsessional thoughts and acts	0.000	0.998	0.001
F42.1 Predominantly compulsive acts [obsessional rituals]	0.000	0.998	0.001
F42.0 Predominantly obsessional thoughts or ruminations	0.000	0.998	0.001
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.998	0.000
Y58.5 Diphtheria vaccine	0.001	0.998	0.000
Y58.4 Tetanus vaccine	0.001	0.998	0.000
Y58.3 Plague vaccine	0.001	0.998	0.000
Y58.2 Cholera vaccine	0.001	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.998	0.000
Y58.0 BCG vaccine	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.001	0.998	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.998	0.002
F48.0 Neurasthenia	0.000	0.998	0.001
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.001	0.998	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.998	0.001
F44.8 Other dissociative [conversion] disorders	0.000	0.998	0.001
F44.7 Mixed dissociative [conversion] disorders	0.000	0.998	0.001
F44.6 Dissociative anaesthesia and sensory loss	0.000	0.998	0.001
F44.4 Dissociative motor disorders	0.000	0.998	0.001
F44.3 Trance and possession disorders	0.000	0.998	0.001
F44.2 Dissociative stupor	0.000	0.998	0.001
F44.1 Dissociative fugue	0.000	0.998	0.001
F44.0 Dissociative amnesia	0.000	0.998	0.001
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.998	0.002
R68.3 Clubbing of fingers	0.000	0.998	0.001
R68.1 Nonspecific symptoms peculiar to infancy	0.000	0.998	0.001
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.4 Other laxatives	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
K56.0 Paralytic ileus	0.000	0.998	0.001
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.998	0.000
Z56.3 Stressful work schedule	0.001	0.998	0.000
R57.2 Septic shock	0.000	0.998	0.001
R57.0 Cardiogenic shock	0.000	0.998	0.001
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.998	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.001	0.998	0.000
Z55.8 Other problems relating to education and literacy	0.001	0.998	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.001	0.998	0.000
Z55.3 Underachievement in school	0.001	0.998	0.000
Z55.2 Failed examinations	0.001	0.998	0.000
Z55.1 Schooling unavailable and unattainable	0.001	0.998	0.000
Z55.0 Illiteracy and low-level literacy	0.001	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.001	0.998	0.000
Z61.8 Other negative life events in childhood	0.001	0.998	0.000
Z61.7 Personal frightening experience in childhood	0.001	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.001	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations