TreeWAS – Variant ID: rs1986731

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
K90 Intestinal malabsorption	0.250	0.750	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.182	0.818	0.000
K90.8 Other intestinal malabsorption	0.179	0.820	0.000
K90.3 Pancreatic steatorrhoea	0.179	0.820	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.179	0.820	0.000
K90.1 Tropical sprue	0.179	0.820	0.000
E83 Disorders of mineral metabolism	0.000	0.886	0.114
E05.9 Thyrotoxicosis, unspecified	0.099	0.901	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.088	0.912	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.084	0.916	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.918	0.082
E83.8 Other disorders of mineral metabolism	0.000	0.918	0.082
E83.2 Disorders of zinc metabolism	0.000	0.918	0.082
E83.0 Disorders of copper metabolism	0.000	0.918	0.082
E83.3 Disorders of phosphorus metabolism	0.000	0.919	0.081
K90.9 Intestinal malabsorption, unspecified	0.079	0.920	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.075	0.925	0.000
E05.8 Other thyrotoxicosis	0.064	0.935	0.000
E05.5 Thyroid crisis or storm	0.063	0.937	0.000
E05.4 Thyrotoxicosis factitia	0.063	0.937	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.063	0.937	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.063	0.937	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.943	0.057
D68 Other coagulation defects	0.033	0.967	0.000
D69 Purpura and other haemorrhagic conditions	0.032	0.967	0.000
D69.6 Thrombocytopenia, unspecified	0.032	0.968	0.000
D68.8 Other specified coagulation defects	0.031	0.969	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.030	0.970	0.000
D68.9 Coagulation defect, unspecified	0.030	0.970	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.030	0.970	0.000
D68.6 Other Thrombophilia	0.028	0.972	0.000
D68.2 Hereditary deficiency of other clotting factors	0.027	0.973	0.000
D68.0 Von Willebrand's disease	0.026	0.974	0.000
D69.9 Haemorrhagic condition, unspecified	0.026	0.974	0.000
D69.4 Other primary thrombocytopenia	0.025	0.975	0.000
D68.4 Acquired coagulation factor deficiency	0.024	0.976	0.000
D68.1 Hereditary factor XI deficiency	0.024	0.976	0.000
D69.8 Other specified haemorrhagic conditions	0.023	0.976	0.000
D69.2 Other nonthrombocytopenic purpura	0.023	0.976	0.000
D69.1 Qualitative platelet defects	0.023	0.976	0.000
D69.0 Allergic purpura	0.023	0.977	0.000
D67 Hereditary factor IX deficiency	0.022	0.978	0.000
D68.5 Primary Thrombophilia	0.021	0.979	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.021	0.979	0.000
D66 Hereditary factor VIII deficiency	0.021	0.979	0.000
K90-K93 Other diseases of the digestive system	0.019	0.981	0.000
C22.9 Liver, unspecified	0.018	0.982	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.018	0.982	0.000
D69.5 Secondary thrombocytopenia	0.017	0.983	0.000
C22.1 Intrahepatic bile duct carcinoma	0.017	0.983	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.016	0.984	0.000
E83.5 Disorders of calcium metabolism	0.000	0.984	0.016
D12.5 Sigmoid colon	0.000	0.985	0.015
K93 Disorders of other digestive organs in diseases classified elsewhere	0.014	0.986	0.000
C22.7 Other specified carcinomas of liver	0.012	0.988	0.000
C22.4 Other sarcomas of liver	0.012	0.988	0.000
C22.3 Angiosarcoma of liver	0.012	0.988	0.000
C22.2 Hepatoblastoma	0.012	0.988	0.000
C22.0 Liver cell carcinoma	0.012	0.988	0.000
E00-E07 Disorders of thyroid gland	0.011	0.989	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.010	0.990	0.000
K93.1 Megacolon in Chagas' disease	0.010	0.990	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.010	0.990	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.991	0.009
E27.1 Primary adrenocortical insufficiency	0.009	0.991	0.000
F33 Recurrent depressive disorder	0.000	0.991	0.009
O16 Unspecified maternal hypertension	0.009	0.991	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.991	0.009
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.008	0.992	0.000
E00 Congenital iodine-deficiency syndrome	0.008	0.992	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.008	0.992	0.000
F30-F39 Mood [affective] disorders	0.000	0.992	0.008
E06 Thyroiditis	0.008	0.992	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.992	0.008
F31 Bipolar affective disorder	0.000	0.992	0.008
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.992	0.008
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.992	0.008
S92.30 Fracture of metatarsal bone (closed)	0.008	0.992	0.000
Z91.5 Personal history of self-harm	0.000	0.993	0.007
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.993	0.007
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.993	0.007
E27.4 Other and unspecified adrenocortical insufficiency	0.007	0.993	0.000
F32 Depressive episode	0.000	0.993	0.007
M47.86 Other spondylosis (Lumbar region)	0.000	0.993	0.007
E27 Other disorders of adrenal gland	0.007	0.993	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.007	0.993	0.000
F43.2 Adjustment disorders	0.000	0.993	0.007
M47.89 Other spondylosis (Site unspecified)	0.000	0.993	0.007
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.993	0.007
F33.8 Other recurrent depressive disorders	0.000	0.993	0.007
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.993	0.007
F34 Persistent mood [affective] disorders	0.000	0.993	0.007
M47.9 Spondylosis, unspecified	0.000	0.993	0.007
M47.8 Other spondylosis	0.000	0.993	0.007
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.993	0.007
S92.3 Fracture of metatarsal bone	0.007	0.993	0.000
E06.9 Thyroiditis, unspecified	0.006	0.993	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.994	0.006
F30 Manic episode	0.000	0.994	0.006
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.994	0.006
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.000	0.994	0.006
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.006	0.994	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.006	0.994	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.006	0.994	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.006	0.994	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.006	0.994	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.006	0.994	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.006	0.994	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.006	0.994	0.000
F38 Other mood [affective] disorders	0.000	0.994	0.006
F39 Unspecified mood [affective] disorder	0.000	0.994	0.006
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.994	0.006
E06.5 Other chronic thyroiditis	0.006	0.994	0.000
E06.4 Drug-induced thyroiditis	0.006	0.994	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.006	0.994	0.000
E06.1 Subacute thyroiditis	0.006	0.994	0.000
E06.0 Acute thyroiditis	0.006	0.994	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.994	0.006
M47 Spondylosis	0.000	0.994	0.006
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.994	0.006
F31.8 Other bipolar affective disorders	0.000	0.994	0.006
F31.7 Bipolar affective disorder, currently in remission	0.000	0.994	0.006
E03 Other hypothyroidism	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.006	0.994	0.000
E27.2 Addisonian crisis	0.006	0.994	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.994	0.006
F34.1 Dysthymia	0.000	0.994	0.006
E04 Other non-toxic goitre	0.006	0.994	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.006	0.994	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.994	0.005
E27.5 Adrenomedullary hyperfunction	0.005	0.994	0.000
E27.0 Other adrenocortical overactivity	0.005	0.994	0.000
F30.0 Hypomania	0.000	0.994	0.005
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E07 Other disorders of thyroid	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.005	0.995	0.000
F43.0 Acute stress reaction	0.000	0.995	0.005
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.995	0.005
S90-S99 Injuries to the ankle and foot	0.005	0.995	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.995	0.005
F34.8 Other persistent mood [affective] disorders	0.000	0.995	0.005
F34.0 Cyclothymia	0.000	0.995	0.005
M47.1 Other spondylosis with myelopathy	0.000	0.995	0.005
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.005	0.995	0.000
S91 Open wound of ankle and foot	0.005	0.995	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.000	0.995	0.005
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.000	0.995	0.005
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.000	0.995	0.005
F32.8 Other depressive episodes	0.000	0.995	0.005
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.995	0.005
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.995	0.005
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.995	0.005
E04.9 Non-toxic goitre, unspecified	0.005	0.995	0.000
S92.31 Fracture of metatarsal bone (open)	0.005	0.995	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.995	0.005
R20.2 Paraesthesia of skin	0.005	0.995	0.000
S92.2 Fracture of other tarsal bone(s)	0.005	0.995	0.000
F32.9 Depressive episode, unspecified	0.000	0.995	0.005
M47.2 Other spondylosis with radiculopathy	0.000	0.995	0.005
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.995	0.005
F43 Reaction to severe stress, and adjustment disorders	0.000	0.995	0.005
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.005
F30.8 Other manic episodes	0.000	0.995	0.005
F30.1 Mania without psychotic symptoms	0.000	0.995	0.005
S93.3 Dislocation of other and unspecified parts of foot	0.005	0.995	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.995	0.005
M47.84 Other spondylosis (Thoracic region)	0.000	0.995	0.005
S92.4 Fracture of great toe	0.005	0.995	0.000
F30.2 Mania with psychotic symptoms	0.000	0.995	0.005
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.995	0.005
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.995	0.004
F38.1 Other recurrent mood [affective] disorders	0.000	0.995	0.004
F38.0 Other single mood [affective] disorders	0.000	0.995	0.004
S91.3 Open wound of other parts of foot	0.005	0.995	0.000
S92.7 Multiple fractures of foot	0.005	0.995	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.995	0.005
J92.0 Pleural plaque with presence of asbestos	0.005	0.995	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.995	0.004
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.995	0.005
E03.5 Myxoedema coma	0.004	0.995	0.000
E03.4 Atrophy of thyroid (acquired)	0.004	0.995	0.000
E03.3 Postinfectious hypothyroidism	0.004	0.995	0.000
E03.1 Congenital hypothyroidism without goitre	0.004	0.995	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.004	0.995	0.000
S92.1 Fracture of talus	0.004	0.995	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.995	0.005
S90 Superficial injury of ankle and foot	0.004	0.995	0.000
S92.9 Fracture of foot, unspecified	0.004	0.995	0.000
C15 Malignant neoplasm of oesophagus	0.004	0.996	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.996	0.004
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.996	0.004
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
C15.9 Oesophagus, unspecified	0.004	0.996	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.996	0.004
N90.4 Leukoplakia of vulva	0.004	0.996	0.000
K91.1 Postgastric surgery syndromes	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.004	0.996	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.004	0.996	0.000
E04.8 Other specified non-toxic goitre	0.004	0.996	0.000
Y60.0 During surgical operation	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
F30.9 Manic episode, unspecified	0.000	0.996	0.004
C15.4 Middle third of oesophagus	0.004	0.996	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.004	0.996	0.000
K91.5 Postcholecystectomy syndrome	0.004	0.996	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.004	0.996	0.000
E07.1 Dyshormogenetic goitre	0.004	0.996	0.000
E07.0 Hypersecretion of calcitonin	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.000	0.996	0.004
D23.5 Skin of trunk	0.000	0.996	0.004
S98 Traumatic amputation of ankle and foot	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.004	0.996	0.000
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
F43.9 Reaction to severe stress, unspecified	0.000	0.996	0.004
C15-C26 Malignant neoplasms of digestive organs	0.004	0.996	0.000
S90.8 Other superficial injuries of ankle and foot	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.004	0.996	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.996	0.004
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.996	0.004
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.996	0.004
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.996	0.004
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.996	0.004
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.996	0.004
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.996	0.004
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
F32.0 Mild depressive episode	0.000	0.996	0.004
S91.7 Multiple open wounds of ankle and foot	0.004	0.996	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.996	0.004
L40.0 Psoriasis vulgaris	0.004	0.996	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.004	0.996	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.996	0.004
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.996	0.004
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.996	0.004
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.996	0.004
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.996	0.004
G37 Other demyelinating diseases of central nervous system	0.000	0.996	0.004
S92.70 Multiple fractures of foot (closed)	0.004	0.996	0.000
F43.8 Other reactions to severe stress	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
C24.0 Extrahepatic bile duct	0.004	0.996	0.000
E03.8 Other specified hypothyroidism	0.004	0.996	0.000
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.004	0.996	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.996	0.000
H54.7 Unspecified visual loss	0.004	0.996	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.004	0.996	0.000
S99 Other and unspecified injuries of ankle and foot	0.004	0.996	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.996	0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.996	0.003
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.996	0.003
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.996	0.003
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.996	0.003
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.996	0.003
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.996	0.003
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.996	0.003
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.996	0.003
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.996	0.003
E29 Testicular dysfunction	0.004	0.996	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.003	0.996	0.000
C24.1 Ampulla of Vater	0.003	0.996	0.000
C15.3 Upper third of oesophagus	0.003	0.996	0.000
E24 Cushing's syndrome	0.003	0.996	0.000
S92.11 Fracture of talus (open)	0.003	0.996	0.000
E07.8 Other specified disorders of thyroid	0.003	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.996	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.996	0.000
S92.91 Fracture of foot, unspecified (open)	0.003	0.996	0.000
S92.90 Fracture of foot, unspecified (closed)	0.003	0.996	0.000
V23.4 Driver injured in traffic accident	0.003	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
N17.9 Acute renal failure, unspecified	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.997	0.003
F32.1 Moderate depressive episode	0.000	0.997	0.003
S90.0 Contusion of ankle	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
Y60.8 During other surgical and medical care	0.003	0.997	0.000
S91.0 Open wound of ankle	0.003	0.997	0.000
R54 Senility	0.003	0.997	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
C24.9 Biliary tract, unspecified	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
C23 Malignant neoplasm of gallbladder	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.997	0.003
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
N05.9 Unspecified	0.000	0.997	0.003
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.997	0.000
S94.1 Injury of medial plantar nerve	0.003	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.997	0.000
S95.1 Injury of plantar artery of foot	0.003	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.003	0.997	0.000
S97.0 Crushing injury of ankle	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.997	0.000
C24.8 Overlapping lesion of biliary tract	0.003	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
K04.8 Radicular cyst	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
S93.40 Sprain of unspecified ligament of ankle	0.003	0.997	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.997	0.003
N64.1 Fat necrosis of breast	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.997	0.003
Z74.0 Reduced mobility	0.003	0.997	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.997	0.003
G37.5 Concentric sclerosis [Balo]	0.000	0.997	0.003
G37.4 Subacute necrotising myelitis	0.000	0.997	0.003
G37.2 Central pontine myelinolysis	0.000	0.997	0.003
G37.1 Central demyelination of corpus callosum	0.000	0.997	0.003
G37.0 Diffuse sclerosis	0.000	0.997	0.003
C17 Malignant neoplasm of small intestine	0.003	0.997	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.003	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.003	0.997	0.000
C26.1 Spleen	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.003	0.997	0.000
F43.1 Posttraumatic stress disorder	0.000	0.997	0.003
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E03.9 Hypothyroidism, unspecified	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.997	0.000
K63.1 Perforation of intestine (nontraumatic)	0.003	0.997	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
M17.0 Primary gonarthrosis, bilateral	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
E26 Hyperaldosteronism	0.002	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
C21 Malignant neoplasm of anus and anal canal	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.002	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.997	0.000
E23.2 Diabetes insipidus	0.002	0.997	0.000
E34.8 Other specified endocrine disorders	0.002	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
C25.2 Tail of pancreas	0.002	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.997	0.000
E25.8 Other adrenogenital disorders	0.002	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.997	0.000
E30.8 Other disorders of puberty	0.002	0.997	0.000
E30.1 Precocious puberty	0.002	0.997	0.000
E30.0 Delayed puberty	0.002	0.997	0.000
E32.9 Disease of thymus, unspecified	0.002	0.997	0.000
E32.8 Other diseases of thymus	0.002	0.997	0.000
E32.1 Abscess of thymus	0.002	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.997	0.000
E22 Hyperfunction of pituitary gland	0.002	0.997	0.000
K91.4 Colostomy and enterostomy malfunction	0.002	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.002
C17.8 Overlapping lesion of small intestine	0.002	0.998	0.000
C17.3 Meckel's diverticulum	0.002	0.998	0.000
C17.1 Jejunum	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
K35.9 Acute appendicitis, unspecified	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
L60.0 Ingrowing nail	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.998	0.002
G72.9 Myopathy, unspecified	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.000	0.998	0.002
N20.0 Calculus of kidney	0.000	0.998	0.002
C25.3 Pancreatic duct	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.998	0.002
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
N92.4 Excessive bleeding in the premenopausal period	0.000	0.998	0.002
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
C21.2 Cloacogenic zone	0.002	0.998	0.000
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
L40.3 Pustulosis palmaris et plantaris	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
C17.2 Ileum	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
L40 Psoriasis	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
D33.3 Cranial nerves	0.000	0.998	0.002
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.998	0.002
Y65.8 Other specified misadventures during surgical and medical care	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
J35.2 Hypertrophy of adenoids	0.000	0.998	0.002
K56.7 Ileus, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations