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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1988565
log Bayes Factor = 48.7948
Chromosome 6   position 32,753,492  (GRCh37) Explore rs1988565 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L57.0 Actinic keratosis
0.000 0.001 0.999
C44.7 Skin of lower limb, including hip
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
C44.6 Skin of upper limb, including shoulder
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.003 0.997
L40.9 Psoriasis, unspecified
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
C44.3 Skin of other and unspecified parts of face
0.000 0.005 0.995
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.010 0.990
E23 Hypofunction and other disorders of pituitary gland
0.000 0.011 0.989
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
E10.9 Without complications
0.000 0.013 0.987
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.014 0.986
E83.1 Disorders of iron metabolism
0.985 0.015 0.000
G37 Other demyelinating diseases of central nervous system
0.984 0.016 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.020 0.980
G37.9 Demyelinating disease of central nervous system, unspecified
0.977 0.023 0.000
L40-L45 Papulosquamous disorders
0.000 0.038 0.962
E11 Non-insulin-dependent diabetes mellitus
0.000 0.043 0.957
E70-E90 Metabolic disorders
0.000 0.045 0.955
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.046 0.954
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.054 0.946
E78.0 Pure hypercholesterolaemia
0.000 0.067 0.933
E23.6 Other disorders of pituitary gland
0.000 0.069 0.931
E23.7 Disorder of pituitary gland, unspecified
0.000 0.074 0.926
C44.4 Skin of scalp and neck
0.000 0.075 0.925
E11.3 With ophthalmic complications
0.000 0.076 0.924
E27 Other disorders of adrenal gland
0.000 0.079 0.921
C44.2 Skin of ear and external auricular canal
0.000 0.081 0.919
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.087 0.913
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.103 0.897
E10.5 With peripheral circulatory complications
0.000 0.111 0.889
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.112 0.888
C44.0 Skin of lip
0.000 0.113 0.887
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.113 0.887
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.114 0.886
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.120 0.880
G37.8 Other specified demyelinating diseases of central nervous system
0.877 0.123 0.000
E06 Thyroiditis
0.000 0.128 0.872
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.135 0.865
E10.1 With ketoacidosis
0.000 0.138 0.862
E78.5 Hyperlipidaemia, unspecified
0.000 0.139 0.861
E27.1 Primary adrenocortical insufficiency
0.000 0.146 0.854
L43 Lichen planus
0.000 0.147 0.853
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.150 0.850
E23.2 Diabetes insipidus
0.000 0.157 0.843
E10.0 With coma
0.000 0.161 0.839
E11.9 Without complications
0.000 0.163 0.837
M10 Gout
0.000 0.172 0.828
E78.2 Mixed hyperlipidaemia
0.000 0.175 0.825
L40.1 Generalised pustular psoriasis
0.000 0.175 0.825
E28 Ovarian dysfunction
0.000 0.183 0.817
E06.3 Autoimmune thyroiditis
0.000 0.184 0.816
E78.6 Lipoprotein deficiency
0.000 0.194 0.806
D00-D09 In situ neoplasms
0.000 0.196 0.804
M06.3 Rheumatoid nodule
0.000 0.197 0.803
M06.0 Seronegative rheumatoid arthritis
0.000 0.197 0.803
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.198 0.802
Chapter II Neoplasms
0.000 0.198 0.802
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.199 0.801
G36 Other acute disseminated demyelination
0.800 0.200 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.200 0.800
D04 Carcinoma in situ of skin
0.000 0.207 0.793
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.209 0.791
D06 Carcinoma in situ of cervix uteri
0.000 0.210 0.790
E04 Other non-toxic goitre
0.000 0.210 0.790
L40.0 Psoriasis vulgaris
0.000 0.210 0.790
E89.0 Postprocedural hypothyroidism
0.000 0.211 0.789
E11.2 With renal complications
0.000 0.211 0.789
E10.2 With renal complications
0.000 0.212 0.788
E23.0 Hypopituitarism
0.000 0.213 0.787
E78.1 Pure hyperglyceridaemia
0.000 0.215 0.785
D06.9 Cervix, unspecified
0.000 0.220 0.780
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.220 0.780
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.222 0.778
E29 Testicular dysfunction
0.000 0.224 0.776
E13 Other specified diabetes mellitus
0.000 0.225 0.775
E24 Cushing's syndrome
0.000 0.227 0.773
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.232 0.768
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.234 0.766
M06.4 Inflammatory polyarthropathy
0.000 0.239 0.761
E88 Other metabolic disorders
0.000 0.247 0.753
C83.3 Large cell (diffuse)
0.000 0.250 0.750
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.256 0.743
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.259 0.741
E11.1 With ketoacidosis
0.000 0.262 0.738
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.262 0.738
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.262 0.738
E10.8 With unspecified complications
0.000 0.264 0.735
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.269 0.731
L40.4 Guttate psoriasis
0.000 0.270 0.730
D04.5 Skin of trunk
0.000 0.272 0.728
E26 Hyperaldosteronism
0.000 0.272 0.728
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.273 0.727
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.273 0.727
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.274 0.726
E84 Cystic fibrosis
0.000 0.278 0.722
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.278 0.722
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
L42 Pityriasis rosea
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
L43.8 Other lichen planus
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E10.6 With other specified complications
0.000 0.286 0.714
L43.9 Lichen planus, unspecified
0.000 0.286 0.714
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.287 0.712
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.291 0.709
E23.1 Drug-induced hypopituitarism
0.000 0.291 0.709
E05.8 Other thyrotoxicosis
0.000 0.291 0.709
E04.0 Non-toxic diffuse goitre
0.000 0.292 0.708
G37.5 Concentric sclerosis [Balo]
0.705 0.295 0.000
G37.4 Subacute necrotising myelitis
0.705 0.295 0.000
G37.2 Central pontine myelinolysis
0.705 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.705 0.295 0.000
G37.0 Diffuse sclerosis
0.705 0.295 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.295 0.705
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.000 0.297 0.703
E11.0 With coma
0.000 0.299 0.701
C85.1 B-cell lymphoma, unspecified
0.000 0.300 0.700
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.300 0.699
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.303 0.697
E79 Disorders of purine and pyrimidine metabolism
0.000 0.303 0.697
E11.8 With unspecified complications
0.000 0.303 0.697
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.304 0.696
C73 Malignant neoplasm of thyroid gland
0.000 0.308 0.692
E28.2 Polycystic ovarian syndrome
0.000 0.308 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.309 0.691
L44 Other papulosquamous disorders
0.000 0.310 0.690
L41 Parapsoriasis
0.000 0.310 0.690
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.310 0.690
E03.8 Other specified hypothyroidism
0.000 0.311 0.689
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.311 0.689
E11.7 With multiple complications
0.000 0.314 0.686
E77 Disorders of glycoprotein metabolism
0.000 0.315 0.685
E76 Disorders of glycosaminoglycan metabolism
0.000 0.315 0.685
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.315 0.685
E70 Disorders of aromatic amino-acid metabolism
0.000 0.315 0.685
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.315 0.685
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.317 0.683
E03.1 Congenital hypothyroidism without goitre
0.000 0.317 0.682
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.319 0.681
E27.9 Disorder of adrenal gland, unspecified
0.000 0.321 0.679
E20 Hypoparathyroidism
0.000 0.321 0.679
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.321 0.679
L57.5 Actinic granuloma
0.000 0.321 0.679
L57.3 Poikiloderma of Civatte
0.000 0.321 0.679
L57.2 Cutis rhomboidalis nuchae
0.000 0.321 0.679
L57.1 Actinic reticuloid
0.000 0.321 0.679
E10.4 With neurological complications
0.000 0.322 0.678
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.322 0.678
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.324 0.676
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.327 0.672
D43.0 Brain, supratentorial
0.000 0.328 0.672
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.329 0.671
M10.9 Gout, unspecified
0.000 0.330 0.670
E89.3 Postprocedural hypopituitarism
0.000 0.331 0.669
D04.7 Skin of lower limb, including hip
0.000 0.332 0.668
G36.0 Neuromyelitis optica [Devic]
0.666 0.334 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.340 0.660
E27.0 Other adrenocortical overactivity
0.000 0.340 0.660
M10.0 Idiopathic gout
0.000 0.342 0.658
E25 Adrenogenital disorders
0.000 0.343 0.657
M12 Other specific arthropathies
0.000 0.343 0.657
L55 Sunburn
0.000 0.345 0.655
E78.4 Other hyperlipidaemia
0.000 0.346 0.654
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.347 0.653
C91 Lymphoid leukaemia
0.000 0.350 0.650
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.649 0.351 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.354 0.646
D09 Carcinoma in situ of other and unspecified sites
0.000 0.354 0.646
E89.4 Postprocedural ovarian failure
0.000 0.357 0.643
C43 Malignant melanoma of skin
0.000 0.358 0.642
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.360 0.640
D04.2 Skin of ear and external auricular canal
0.000 0.361 0.639
D04.4 Skin of scalp and neck
0.000 0.362 0.638
D46 Myelodysplastic syndromes
0.000 0.362 0.638
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.362 0.638
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.362 0.638
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.364 0.635
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.367 0.633
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.367 0.632
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.369 0.631
M05.2 Rheumatoid vasculitis
0.000 0.370 0.630
E06.5 Other chronic thyroiditis
0.000 0.375 0.625
E06.4 Drug-induced thyroiditis
0.000 0.375 0.625
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.375 0.625
E06.0 Acute thyroiditis
0.000 0.375 0.625
E06.9 Thyroiditis, unspecified
0.000 0.378 0.622
M11 Other crystal arthropathies
0.000 0.378 0.622
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.378 0.622
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.379 0.621
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.379 0.620
E89.5 Postprocedural testicular hypofunction
0.000 0.379 0.620
E11.6 With other specified complications
0.000 0.380 0.620
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.381 0.619
E29.1 Testicular hypofunction
0.000 0.381 0.619
D04.9 Skin, unspecified
0.000 0.382 0.618
E88.8 Other specified metabolic disorders
0.000 0.386 0.614
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.386 0.613
E27.8 Other specified disorders of adrenal gland
0.000 0.386 0.613
E13.9 Without complications
0.000 0.387 0.613
M06.34 Rheumatoid nodule (Hand)
0.000 0.388 0.612
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.389 0.611
L43.3 Subacute (active) lichen planus
0.000 0.389 0.611
L43.2 Lichenoid drug reaction
0.000 0.389 0.611
L43.1 Bullous lichen planus
0.000 0.389 0.611
L43.0 Hypertrophic lichen planus
0.000 0.389 0.611
E04.9 Non-toxic goitre, unspecified
0.000 0.390 0.610
C82.0 Small cleaved cell, follicular
0.000 0.391 0.609
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.391 0.609
E78.3 Hyperchylomicronaemia
0.000 0.391 0.608
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.398 0.602
D03 Melanoma in situ
0.000 0.399 0.601
L58 Radiodermatitis
0.000 0.399 0.601
C83.1 Small cleaved cell (diffuse)
0.000 0.401 0.599
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.401 0.599
E89.1 Postprocedural hypoinsulinaemia
0.000 0.401 0.599
E89.2 Postprocedural hypoparathyroidism
0.000 0.403 0.597
E80.4 Gilbert's syndrome
0.000 0.404 0.596
C83.7 Burkitt's tumour
0.000 0.404 0.596
M10.4 Other secondary gout
0.000 0.406 0.594
M10.2 Drug-induced gout
0.000 0.406 0.594
M10.1 Lead-induced gout
0.000 0.406 0.594
E74 Other disorders of carbohydrate metabolism
0.000 0.406 0.594
E24.0 Pituitary-dependent Cushing's disease
0.000 0.407 0.593
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.408 0.592
E73 Lactose intolerance
0.000 0.410 0.590
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.410 0.590
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.411 0.589
E72 Other disorders of amino-acid metabolism
0.000 0.413 0.587
L82 Seborrhoeic keratosis
0.000 0.413 0.587
D47.1 Chronic myeloproliferative disease
0.000 0.414 0.586
M10.90 Gout, unspecified (Multiple sites)
0.000 0.414 0.586
E28.9 Ovarian dysfunction, unspecified
0.000 0.414 0.585
E28.8 Other ovarian dysfunction
0.000 0.414 0.585
E28.1 Androgen excess
0.000 0.414 0.585
E28.0 Oestrogen excess
0.000 0.414 0.585
D47.2 Monoclonal gammopathy
0.000 0.415 0.585
E04.2 Non-toxic multinodular goitre
0.000 0.415 0.585
E21.3 Hyperparathyroidism, unspecified
0.000 0.416 0.584
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.418 0.582
E28.3 Primary ovarian failure
0.000 0.421 0.579
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.422 0.578
M10.3 Gout due to impairment of renal function
0.000 0.423 0.577
E24.9 Cushing's syndrome, unspecified
0.000 0.424 0.576
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.424 0.576
M06.38 Rheumatoid nodule (Other)
0.000 0.424 0.576
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.424 0.576
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.424 0.576
M06.33 Rheumatoid nodule (Forearm)
0.000 0.424 0.576
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.424 0.576
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.424 0.576
E88.2 Lipomatosis, not elsewhere classified
0.000 0.424 0.576
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.424 0.576
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.424 0.576
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.424 0.576
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.424 0.576
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.424 0.576
E85 Amyloidosis
0.000 0.426 0.574
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.426 0.574
C94 Other leukaemias of specified cell type
0.000 0.426 0.574
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.426 0.574
G36.9 Acute disseminated demyelination, unspecified
0.574 0.426 0.000
G36.8 Other specified acute disseminated demyelination
0.574 0.426 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.574 0.426 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.427 0.573
D06.0 Endocervix
0.000 0.428 0.572
C91.9 Lymphoid leukaemia, unspecified
0.000 0.429 0.571
E11.5 With peripheral circulatory complications
0.000 0.429 0.571
E21.0 Primary hyperparathyroidism
0.000 0.430 0.570
L10-L14 Bullous disorders
0.000 0.430 0.570
D04.8 Skin of other sites
0.000 0.432 0.568
D04.0 Skin of lip
0.000 0.432 0.568
C12 Malignant neoplasm of pyriform sinus
0.000 0.432 0.568
M14 Arthropathies in other diseases classified elsewhere
0.000 0.432 0.567
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.433 0.567
C85.0 Lymphosarcoma
0.000 0.433 0.567
D06.7 Other parts of cervix
0.000 0.433 0.566
D06.1 Exocervix
0.000 0.433 0.566
E04.8 Other specified non-toxic goitre
0.000 0.433 0.566
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.438 0.562
L57.4 Cutis laxa senilis
0.000 0.439 0.561
C86 Other specified types of T/NK-cell lymphoma
0.000 0.440 0.560
E88.9 Metabolic disorder, unspecified
0.000 0.440 0.560
C93 Monocytic leukaemia
0.000 0.440 0.559
E24.2 Drug-induced Cushing's syndrome
0.000 0.442 0.558
E21.4 Other specified disorders of parathyroid gland
0.000 0.442 0.558
E29.9 Testicular dysfunction, unspecified
0.000 0.443 0.556
E29.8 Other testicular dysfunction
0.000 0.443 0.556
E29.0 Testicular hyperfunction
0.000 0.443 0.556
E13.8 With unspecified complications
0.000 0.444 0.555
E13.7 With multiple complications
0.000 0.444 0.555
E13.6 With other specified complications
0.000 0.444 0.555
E13.5 With peripheral circulatory complications
0.000 0.444 0.555
E13.4 With neurological complications
0.000 0.444 0.555
E13.3 With ophthalmic complications
0.000 0.444 0.555
E13.2 With renal complications
0.000 0.444 0.555
E13.1 With ketoacidosis
0.000 0.444 0.555
E13.0 With coma
0.000 0.444 0.555
E84.9 Cystic fibrosis, unspecified
0.000 0.445 0.554
E24.8 Other Cushing's syndrome
0.000 0.445 0.554
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.445 0.554
E24.3 Ectopic ACTH syndrome
0.000 0.445 0.554
E24.1 Nelson's syndrome
0.000 0.445 0.554
C88 Malignant immunoproliferative diseases
0.000 0.446 0.554
C07 Malignant neoplasm of parotid gland
0.000 0.447 0.553
C83.6 Undifferentiated (diffuse)
0.000 0.451 0.549
C83.5 Lymphoblastic (diffuse)
0.000 0.451 0.549
C83.4 Immunoblastic (diffuse)
0.000 0.451 0.549
C83.2 Mixed small and large cell (diffuse)
0.000 0.451 0.549
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.452 0.548
E78.8 Other disorders of lipoprotein metabolism
0.000 0.454 0.546
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.454 0.546
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.454 0.546
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.454 0.546
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.454 0.546
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.454 0.546
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.454 0.546
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.454 0.546
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.454 0.546
E21.2 Other hyperparathyroidism
0.000 0.456 0.544
E88.3 Tumour lysis syndrome
0.000 0.460 0.540
L85 Other epidermal thickening
0.000 0.461 0.539
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.000 0.463 0.537
E26.0 Primary hyperaldosteronism
0.000 0.464 0.536
C03 Malignant neoplasm of gum
0.000 0.464 0.536
C02.9 Tongue, unspecified
0.000 0.464 0.536
C82.2 Large cell, follicular
0.000 0.464 0.536
M10.09 Idiopathic gout (Site unspecified)
0.000 0.465 0.535
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.465 0.535
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.466 0.534
E80.1 Porphyria cutanea tarda
0.000 0.467 0.533
D01.0 Colon
0.000 0.469 0.531
L94 Other localised connective tissue disorders
0.000 0.469 0.531
M13 Other arthritis
0.000 0.469 0.531
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.470 0.530
D43.2 Brain, unspecified
0.000 0.470 0.530
D43.4 Spinal cord
0.000 0.471 0.529
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.471 0.529
E80.6 Other disorders of bilirubin metabolism
0.000 0.471 0.528
D46.2 Refractory anaemia with excess of blasts
0.000 0.474 0.526
L56.3 Solar urticaria
0.000 0.476 0.524
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.476 0.524
L56.1 Drug photoallergic response
0.000 0.476 0.524
L56.0 Drug phototoxic response
0.000 0.476 0.524
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.477 0.523
E40-E46 Malnutrition
0.000 0.477 0.522
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.478 0.522
E26.9 Hyperaldosteronism, unspecified
0.000 0.478 0.522
E26.8 Other hyperaldosteronism
0.000 0.478 0.522
E26.1 Secondary hyperaldosteronism
0.000 0.478 0.522
D48.5 Skin
0.000 0.478 0.522
C02.1 Border of tongue
0.000 0.479 0.521
C95 Leukaemia of unspecified cell type
0.000 0.480 0.520
E84.8 Cystic fibrosis with other manifestations
0.000 0.482 0.517
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.482 0.517
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.482 0.517
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.482 0.517
E80.5 Crigler-Najjar syndrome
0.000 0.482 0.517
E80.3 Defects of catalase and peroxydase
0.000 0.482 0.517
E80.0 Hereditary erythropoietic porphyria
0.000 0.482 0.517
L85.8 Other specified epidermal thickening
0.000 0.483 0.517
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.484 0.516
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.484 0.516
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.486 0.514
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.486 0.514
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.486 0.514
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.486 0.514
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.486 0.514
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.486 0.514
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.486 0.514
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.486 0.514
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.486 0.514
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.486 0.514
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.486 0.514
M07.18 Arthritis mutilans (Other)
0.000 0.486 0.514
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.486 0.514
M07.16 Arthritis mutilans (Lower leg)
0.000 0.486 0.514
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.486 0.514
M07.14 Arthritis mutilans (Hand)
0.000 0.486 0.514
M07.13 Arthritis mutilans (Forearm)
0.000 0.486 0.514
M07.12 Arthritis mutilans (Upper arm)
0.000 0.486 0.514
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.486 0.514
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.486 0.514
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.486 0.514
M07.28 Psoriatic spondylitis (Other)
0.000 0.486 0.514
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.486 0.514
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.486 0.514
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.486 0.514
M07.24 Psoriatic spondylitis (Hand)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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