TreeWAS – Variant ID: rs200988

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.999	0.001	0.000
R31 Unspecified haematuria	0.000	0.001	0.999
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.001	0.999
E05.9 Thyrotoxicosis, unspecified	0.999	0.001	0.000
N40-N51 Diseases of male genital organs	0.000	0.002	0.998
N41 Inflammatory diseases of prostate	0.000	0.002	0.998
E03 Other hypothyroidism	0.998	0.002	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.998	0.002	0.000
E03.9 Hypothyroidism, unspecified	0.997	0.003	0.000
E16 Other disorders of pancreatic internal secretion	0.996	0.004	0.000
E16.2 Hypoglycaemia, unspecified	0.994	0.006	0.000
K40 Inguinal hernia	0.000	0.008	0.992
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.009	0.991
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.017	0.983
E10.3 With ophthalmic complications	0.978	0.022	0.000
N41.0 Acute prostatitis	0.000	0.024	0.976
N42 Other disorders of prostate	0.000	0.028	0.972
E14 Unspecified diabetes mellitus	0.963	0.037	0.000
N42.8 Other specified disorders of prostate	0.000	0.042	0.958
N41.1 Chronic prostatitis	0.000	0.044	0.956
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.066	0.934
E20-E35 Disorders of other endocrine glands	0.925	0.075	0.000
E10.1 With ketoacidosis	0.923	0.077	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.888	0.112	0.000
K90 Intestinal malabsorption	0.887	0.113	0.000
N46 Male infertility	0.000	0.119	0.881
E27 Other disorders of adrenal gland	0.860	0.140	0.000
E14.3 With ophthalmic complications	0.856	0.144	0.000
E10.2 With renal complications	0.855	0.145	0.000
E23 Hypofunction and other disorders of pituitary gland	0.850	0.150	0.000
N42.0 Calculus of prostate	0.000	0.151	0.849
E10.6 With other specified complications	0.844	0.156	0.000
E27.1 Primary adrenocortical insufficiency	0.840	0.160	0.000
E14.9 Without complications	0.834	0.166	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.831	0.169	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.826	0.174	0.000
E14.4 With neurological complications	0.819	0.181	0.000
E10.0 With coma	0.809	0.191	0.000
K90.9 Intestinal malabsorption, unspecified	0.807	0.193	0.000
E10.4 With neurological complications	0.805	0.195	0.000
N44 Torsion of testis	0.000	0.195	0.805
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.799	0.201	0.000
N45 Orchitis and epididymitis	0.000	0.219	0.781
N42.1 Congestion and haemorrhage of prostate	0.000	0.234	0.766
E10.7 With multiple complications	0.762	0.238	0.000
E23.2 Diabetes insipidus	0.761	0.239	0.000
E24 Cushing's syndrome	0.752	0.248	0.000
E20 Hypoparathyroidism	0.733	0.267	0.000
E07 Other disorders of thyroid	0.732	0.268	0.000
E16.1 Other hypoglycaemia	0.719	0.281	0.000
E27.9 Disorder of adrenal gland, unspecified	0.718	0.282	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E23.0 Hypopituitarism	0.717	0.283	0.000
E03.5 Myxoedema coma	0.715	0.284	0.000
E03.4 Atrophy of thyroid (acquired)	0.715	0.284	0.000
E03.3 Postinfectious hypothyroidism	0.715	0.284	0.000
E03.1 Congenital hypothyroidism without goitre	0.715	0.284	0.000
N41.3 Prostatocystitis	0.000	0.284	0.715
N41.2 Abscess of prostate	0.000	0.284	0.715
E15 Nondiabetic hypoglycaemic coma	0.715	0.285	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.714	0.286	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.714	0.286	0.000
E16.4 Abnormal secretion of gastrin	0.714	0.286	0.000
E16.3 Increased secretion of glucagon	0.714	0.286	0.000
E10.5 With peripheral circulatory complications	0.713	0.287	0.000
E14.2 Withrenal complications	0.711	0.289	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.289	0.711
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.289	0.711
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.291	0.709
E03.0 Congenital hypothyroidism with diffuse goitre	0.704	0.296	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.700	0.300	0.000
E14.8 With unspecified complications	0.697	0.303	0.000
N42.3 Dysplasia of prostate	0.000	0.303	0.697
E14.5 With peripheral circulatory complications	0.693	0.307	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.309	0.691
E14.6 With other specified complications	0.691	0.309	0.000
E14.7 With multiple complications	0.690	0.310	0.000
E14.0 With coma	0.690	0.310	0.000
E31 Polyglandular dysfunction	0.688	0.311	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.679	0.321	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.329	0.671
E25 Adrenogenital disorders	0.667	0.333	0.000
K90.8 Other intestinal malabsorption	0.666	0.334	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.663	0.336	0.000
E32 Diseases of thymus	0.663	0.336	0.000
E30 Disorders of puberty, not elsewhere classified	0.663	0.336	0.000
E05.8 Other thyrotoxicosis	0.662	0.338	0.000
E14.1 With ketoacidosis	0.658	0.342	0.000
E13 Other specified diabetes mellitus	0.654	0.346	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.347	0.653
K90.3 Pancreatic steatorrhoea	0.636	0.364	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.636	0.364	0.000
K90.1 Tropical sprue	0.636	0.364	0.000
E10.8 With unspecified complications	0.623	0.377	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.621	0.379	0.000
E23.7 Disorder of pituitary gland, unspecified	0.618	0.382	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.383	0.617
E27.5 Adrenomedullary hyperfunction	0.616	0.383	0.000
E27.0 Other adrenocortical overactivity	0.616	0.383	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.610	0.390	0.000
E23.1 Drug-induced hypopituitarism	0.610	0.390	0.000
E21.3 Hyperparathyroidism, unspecified	0.608	0.392	0.000
E27.2 Addisonian crisis	0.599	0.401	0.000
E20.9 Hypoparathyroidism, unspecified	0.595	0.405	0.000
E24.0 Pituitary-dependent Cushing's disease	0.594	0.406	0.000
E24.2 Drug-induced Cushing's syndrome	0.594	0.406	0.000
E03.8 Other specified hypothyroidism	0.593	0.407	0.000
E40-E46 Malnutrition	0.586	0.414	0.000
E07.8 Other specified disorders of thyroid	0.586	0.414	0.000
E23.6 Other disorders of pituitary gland	0.580	0.420	0.000
E34 Other endocrine disorders	0.573	0.427	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.430	0.570
E06 Thyroiditis	0.559	0.441	0.000
E50-E64 Other nutritional deficiencies	0.559	0.441	0.000
E29 Testicular dysfunction	0.558	0.442	0.000
E24.8 Other Cushing's syndrome	0.539	0.461	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.539	0.461	0.000
E24.3 Ectopic ACTH syndrome	0.539	0.461	0.000
E24.1 Nelson's syndrome	0.539	0.461	0.000
E26 Hyperaldosteronism	0.533	0.467	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.000	0.468	0.532
E28 Ovarian dysfunction	0.531	0.469	0.000
E21.0 Primary hyperparathyroidism	0.529	0.471	0.000
E24.9 Cushing's syndrome, unspecified	0.526	0.474	0.000
E20.8 Other hypoparathyroidism	0.525	0.474	0.000
E20.1 Pseudohypoparathyroidism	0.525	0.474	0.000
E20.0 Idiopathic hypoparathyroidism	0.525	0.474	0.000
N42.2 Atrophy of prostate	0.000	0.475	0.525
E07.1 Dyshormogenetic goitre	0.525	0.475	0.000
E07.0 Hypersecretion of calcitonin	0.525	0.475	0.000
E31.0 Autoimmune polyglandular failure	0.519	0.481	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.000	0.491	0.508
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.000	0.491	0.508
N51.0 Disorders of prostate in diseases classified elsewhere	0.000	0.491	0.508
E27.4 Other and unspecified adrenocortical insufficiency	0.508	0.492	0.000
N51.2 Balanitis in diseases classified elsewhere	0.000	0.498	0.502
E21.2 Other hyperparathyroidism	0.502	0.498	0.000
E21.4 Other specified disorders of parathyroid gland	0.502	0.498	0.000
E11 Non-insulin-dependent diabetes mellitus	0.500	0.500	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.000	0.505	0.495
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.000	0.505	0.495
N49.0 Inflammatory disorders of seminal vesicle	0.000	0.505	0.495
E31.9 Polyglandular dysfunction, unspecified	0.494	0.506	0.000
E31.8 Other polyglandular dysfunction	0.494	0.506	0.000
E31.1 Polyglandular hyperfunction	0.494	0.506	0.000
E13.3 With ophthalmic complications	0.489	0.511	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.481	0.519	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.481	0.519	0.000
E25.9 Adrenogenital disorder, unspecified	0.478	0.522	0.000
E25.8 Other adrenogenital disorders	0.478	0.522	0.000
E30.9 Disorder of puberty, unspecified	0.476	0.524	0.000
E30.8 Other disorders of puberty	0.476	0.524	0.000
E30.1 Precocious puberty	0.476	0.524	0.000
E30.0 Delayed puberty	0.476	0.524	0.000
E32.9 Disease of thymus, unspecified	0.476	0.524	0.000
E32.8 Other diseases of thymus	0.476	0.524	0.000
E32.1 Abscess of thymus	0.476	0.524	0.000
E32.0 Persistent hyperplasia of thymus	0.476	0.524	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.476	0.524	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.476	0.524	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.476	0.524	0.000
E11.3 With ophthalmic complications	0.473	0.527	0.000
E13.8 With unspecified complications	0.469	0.531	0.000
E13.7 With multiple complications	0.469	0.531	0.000
E13.6 With other specified complications	0.469	0.531	0.000
E13.5 With peripheral circulatory complications	0.469	0.531	0.000
E13.4 With neurological complications	0.469	0.531	0.000
E13.2 With renal complications	0.469	0.531	0.000
E13.1 With ketoacidosis	0.469	0.531	0.000
E13.0 With coma	0.469	0.531	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.532	0.468
E22 Hyperfunction of pituitary gland	0.460	0.540	0.000
E07.9 Disorder of thyroid, unspecified	0.459	0.541	0.000
E11.5 With peripheral circulatory complications	0.449	0.550	0.000
E53 Deficiency of other B group vitamins	0.434	0.566	0.000
E34.8 Other specified endocrine disorders	0.430	0.569	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.425	0.575	0.000
N48 Other disorders of penis	0.000	0.579	0.421
E44 Protein-energy malnutrition of moderate and mild degree	0.420	0.580	0.000
E45 Retarded development following protein-energy malnutrition	0.420	0.580	0.000
E43 Unspecified severe protein-energy malnutrition	0.420	0.580	0.000
E42 Marasmic kwashiorkor	0.420	0.580	0.000
E41 Nutritional marasmus	0.420	0.580	0.000
E40 Kwashiorkor	0.420	0.580	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.580	0.420
E34.5 Androgen resistance syndrome	0.411	0.589	0.000
E34.4 Constitutional tall stature	0.411	0.589	0.000
E34.3 Short stature, not elsewhere classified	0.411	0.589	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.411	0.589	0.000
E34.1 Other hypersecretion of intestinal hormones	0.411	0.589	0.000
E51 Thiamine deficiency	0.409	0.591	0.000
E28.3 Primary ovarian failure	0.408	0.592	0.000
E06.5 Other chronic thyroiditis	0.407	0.593	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.406	0.594	0.000
N48.4 Impotence of organic origin	0.000	0.596	0.404
E06.4 Drug-induced thyroiditis	0.401	0.599	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.401	0.599	0.000
E06.1 Subacute thyroiditis	0.401	0.599	0.000
E06.0 Acute thyroiditis	0.401	0.599	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.401	0.599	0.000
E63 Other nutritional deficiencies	0.401	0.599	0.000
E50 Vitamin A deficiency	0.401	0.599	0.000
E60 Dietary zinc deficiency	0.401	0.599	0.000
E59 Dietary selenium deficiency	0.401	0.599	0.000
E54 Ascorbic acid deficiency	0.401	0.599	0.000
E52 Niacin deficiency [pellagra]	0.401	0.599	0.000
E29.9 Testicular dysfunction, unspecified	0.400	0.600	0.000
E29.8 Other testicular dysfunction	0.400	0.600	0.000
E29.0 Testicular hyperfunction	0.400	0.600	0.000
E58 Dietary calcium deficiency	0.388	0.612	0.000
E34.0 Carcinoid syndrome	0.388	0.612	0.000
E11.6 With other specified complications	0.386	0.614	0.000
E56 Other vitamin deficiencies	0.383	0.616	0.000
E26.9 Hyperaldosteronism, unspecified	0.382	0.617	0.000
E26.8 Other hyperaldosteronism	0.382	0.617	0.000
E26.1 Secondary hyperaldosteronism	0.382	0.617	0.000
E28.9 Ovarian dysfunction, unspecified	0.381	0.619	0.000
E28.8 Other ovarian dysfunction	0.381	0.619	0.000
E28.1 Androgen excess	0.381	0.619	0.000
E28.0 Oestrogen excess	0.381	0.619	0.000
E13.9 Without complications	0.376	0.624	0.000
E06.9 Thyroiditis, unspecified	0.374	0.625	0.000
N48.2 Other inflammatory disorders of penis	0.000	0.628	0.372
E61 Deficiency of other nutrient elements	0.365	0.635	0.000
E53.8 Deficiency of other specified B group vitamins	0.361	0.639	0.000
E11.7 With multiple complications	0.359	0.641	0.000
E11.0 With coma	0.354	0.646	0.000
E11.1 With ketoacidosis	0.341	0.659	0.000
E22.1 Hyperprolactinaemia	0.338	0.662	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.667	0.333
E22.9 Hyperfunction of pituitary gland, unspecified	0.330	0.670	0.000
E22.8 Other hyperfunction of pituitary gland	0.330	0.670	0.000
N43 Hydrocele and spermatocele	0.000	0.672	0.327
E34.9 Endocrine disorder, unspecified	0.322	0.678	0.000
E53.1 Pyridoxine deficiency	0.311	0.688	0.000
E53.0 Riboflavin deficiency	0.311	0.688	0.000
N48.5 Ulcer of penis	0.000	0.692	0.308
E51.2 Wernicke's encephalopathy	0.302	0.698	0.000
E44.1 Mild protein-energy malnutrition	0.301	0.698	0.000
E44.0 Moderate protein-energy malnutrition	0.301	0.698	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.296	0.704	0.000
E29.1 Testicular hypofunction	0.295	0.705	0.000
E51.9 Thiamine deficiency, unspecified	0.293	0.706	0.000
E51.8 Other manifestations of thiamine deficiency	0.293	0.706	0.000
E51.1 Beriberi	0.293	0.706	0.000
E11.8 With unspecified complications	0.292	0.708	0.000
E46 Unspecified protein-energy malnutrition	0.289	0.711	0.000
E50.9 Vitamin A deficiency, unspecified	0.287	0.712	0.000
E50.8 Other manifestations of vitamin A deficiency	0.287	0.712	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.287	0.712	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.287	0.712	0.000
E50.5 Vitamin A deficiency with night blindness	0.287	0.712	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.287	0.712	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.287	0.712	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.287	0.712	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.287	0.712	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.287	0.712	0.000
E63.9 Nutritional deficiency, unspecified	0.287	0.712	0.000
E63.8 Other specified nutritional deficiencies	0.287	0.712	0.000
E63.1 Imbalance of constituents of food intake	0.287	0.712	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.287	0.712	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.287	0.712	0.000
E64.8 Sequelae of other nutritional deficiencies	0.287	0.712	0.000
E64.3 Sequelae of rickets	0.287	0.712	0.000
E64.2 Sequelae of vitamin C deficiency	0.287	0.712	0.000
E64.1 Sequelae of vitamin A deficiency	0.287	0.712	0.000
E64.0 Sequelae of protein-energy malnutrition	0.287	0.712	0.000
E53.9 Vitamin B deficiency, unspecified	0.284	0.715	0.000
E06.3 Autoimmune thyroiditis	0.276	0.724	0.000
E56.9 Vitamin deficiency, unspecified	0.275	0.725	0.000
E56.8 Deficiency of other vitamins	0.275	0.725	0.000
E56.0 Deficiency of vitamin E	0.275	0.725	0.000
E55 Vitamin D deficiency	0.270	0.730	0.000
E65-E68 Obesity and other hyperalimentation	0.267	0.733	0.000
E61.1 Iron deficiency	0.267	0.733	0.000
E61.9 Deficiency of nutrient element, unspecified	0.262	0.738	0.000
E61.8 Deficiency of other specified nutrient elements	0.262	0.738	0.000
E61.7 Deficiency of multiple nutrient elements	0.262	0.738	0.000
E61.6 Vanadium deficiency	0.262	0.738	0.000
E61.5 Molybdenum deficiency	0.262	0.738	0.000
E61.4 Chromium deficiency	0.262	0.738	0.000
E61.3 Manganese deficiency	0.262	0.738	0.000
E61.0 Copper deficiency	0.262	0.738	0.000
E56.1 Deficiency of vitamin K	0.258	0.742	0.000
E26.0 Primary hyperaldosteronism	0.252	0.748	0.001
N43.2 Other hydrocele	0.000	0.765	0.235
N43.1 Infected hydrocele	0.000	0.765	0.235
N43.0 Encysted hydrocele	0.000	0.765	0.235
N48.0 Leukoplakia of penis	0.000	0.765	0.235
N47 Redundant prepuce, phimosis and paraphimosis	0.000	0.769	0.231
N48.3 Priapism	0.000	0.776	0.224
N48.1 Balanoposthitis	0.000	0.777	0.223
E61.2 Magnesium deficiency	0.219	0.781	0.000
E27.8 Other specified disorders of adrenal gland	0.205	0.791	0.003
E55.0 Rickets, active	0.193	0.806	0.000
E67 Other hyperalimentation	0.192	0.808	0.000
E68 Sequelae of hyperalimentation	0.192	0.808	0.000
E28.2 Polycystic ovarian syndrome	0.186	0.814	0.000
I83 Varicose veins of lower extremities	0.000	0.818	0.182
E22.0 Acromegaly and pituitary gigantism	0.177	0.823	0.001
N43.4 Spermatocele	0.001	0.833	0.166
K40-K46 Hernia	0.000	0.845	0.155
N48.9 Disorder of penis, unspecified	0.001	0.849	0.151
N50 Other disorders of male genital organs	0.000	0.853	0.147
N48.8 Other specified disorders of penis	0.000	0.857	0.143
K41 Femoral hernia	0.000	0.861	0.139
E67.8 Other specified hyperalimentation	0.137	0.862	0.000
E67.3 Hypervitaminosis D	0.137	0.862	0.000
E67.2 Megavitamin-B6 syndrome	0.137	0.862	0.000
E67.1 Hypercarotenaemia	0.137	0.862	0.000
E67.0 Hypervitaminosis A	0.137	0.862	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.863	0.137
E11.2 With renal complications	0.133	0.866	0.001
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.869	0.131
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.878	0.122
K46 Unspecified abdominal hernia	0.000	0.879	0.121
E83 Disorders of mineral metabolism	0.004	0.880	0.117
E04 Other non-toxic goitre	0.116	0.884	0.000
E65 Localised adiposity	0.102	0.897	0.001
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.899	0.101
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.900	0.100
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.900	0.100
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.900	0.100
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.900	0.100
N50.9 Disorder of male genital organs, unspecified	0.000	0.900	0.099
N50.0 Atrophy of testis	0.000	0.902	0.098
K44 Diaphragmatic hernia	0.000	0.903	0.097
N48.6 Balanitis xerotica obliterans	0.000	0.905	0.095
E83.3 Disorders of phosphorus metabolism	0.001	0.906	0.093
D64.9 Anaemia, unspecified	0.089	0.911	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.913	0.087
E83.9 Disorder of mineral metabolism, unspecified	0.003	0.914	0.084
E83.8 Other disorders of mineral metabolism	0.003	0.914	0.084
E83.2 Disorders of zinc metabolism	0.003	0.914	0.084
E83.0 Disorders of copper metabolism	0.003	0.914	0.084
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.916	0.084
E04.8 Other specified non-toxic goitre	0.083	0.916	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.920	0.080
E04.0 Non-toxic diffuse goitre	0.078	0.922	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.924	0.076
R30.0 Dysuria	0.000	0.928	0.072
R30 Pain associated with micturition	0.000	0.930	0.070
K44.1 Diaphragmatic hernia with gangrene	0.000	0.930	0.069
R30-R39 Symptoms and signs involving the urinary system	0.000	0.932	0.068
K42 Umbilical hernia	0.000	0.934	0.066
E55.9 Vitamin D deficiency, unspecified	0.062	0.937	0.000
R30.1 Vesical tenesmus	0.000	0.941	0.059
K45 Other abdominal hernia	0.001	0.941	0.058
K43 Ventral hernia	0.000	0.945	0.054
K90-K93 Other diseases of the digestive system	0.053	0.946	0.000
E11.4 With neurological complications	0.052	0.947	0.001
N43.3 Hydrocele, unspecified	0.000	0.949	0.051
K42.1 Umbilical hernia with gangrene	0.000	0.952	0.047
R30.9 Painful micturition, unspecified	0.000	0.952	0.047
E04.9 Non-toxic goitre, unspecified	0.047	0.953	0.000
R36 Urethral discharge	0.000	0.954	0.046
D64 Other anaemias	0.044	0.956	0.000
E11.9 Without complications	0.044	0.956	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.957	0.043
K45.1 Other specified abdominal hernia with gangrene	0.001	0.958	0.042
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.961	0.039
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.961	0.039
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.961	0.039
K43.4 Parastomal hernia with gangrene	0.000	0.961	0.039
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.961	0.039
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.961	0.039
K43.1 Ventral hernia with gangrene	0.000	0.961	0.039
K93 Disorders of other digestive organs in diseases classified elsewhere	0.038	0.961	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.962	0.038
E83.4 Disorders of magnesium metabolism	0.002	0.964	0.034
R34 Anuria and oliguria	0.000	0.965	0.035
R47.0 Dysphasia and aphasia	0.035	0.965	0.000
D64.3 Other sideroblastic anaemias	0.033	0.966	0.000
D64.4 Congenital dyserythropoietic anaemia	0.032	0.968	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.032	0.968	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.032	0.968	0.000
D64.0 Hereditary sideroblastic anaemia	0.032	0.968	0.000
E04.1 Non-toxic single thyroid nodule	0.031	0.969	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.000	0.970	0.030
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.001	0.970	0.028
D86.9 Sarcoidosis, unspecified	0.029	0.971	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.972	0.028
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.028	0.972	0.000
K93.1 Megacolon in Chagas' disease	0.028	0.972	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.028	0.972	0.000
D86 Sarcoidosis	0.028	0.972	0.000
D80-D89 Certain disorders involving the immune mechanism	0.027	0.973	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.973	0.027
E66 Obesity	0.026	0.974	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.026	0.974	0.000
S20 Superficial injury of thorax	0.026	0.974	0.000
S20.2 Contusion of thorax	0.025	0.975	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.025	0.975	0.000
S20.3 Other superficial injuries of front wall of thorax	0.024	0.976	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.024	0.976	0.000
D64.8 Other specified anaemias	0.024	0.976	0.000
D86.0 Sarcoidosis of lung	0.024	0.976	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.977	0.023
D89.9 Disorder involving the immune mechanism, unspecified	0.023	0.977	0.000
D86.1 Sarcoidosis of lymph nodes	0.021	0.978	0.000
D60-D64 Aplastic and other anaemias	0.021	0.979	0.000
A04 Other bacterial intestinal infections	0.000	0.979	0.021
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.979	0.020
D80 Immunodeficiency with predominantly antibody defects	0.020	0.980	0.000
S20.1 Other and unspecified superficial injuries of breast	0.020	0.980	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.020	0.980	0.000
D83 Common variable immunodeficiency	0.020	0.980	0.000
D86.8 Sarcoidosis of other and combined sites	0.020	0.980	0.000
D89.1 Cryoglobulinaemia	0.020	0.980	0.000
D82 Immunodeficiency associated with other major defects	0.019	0.981	0.000
D81 Combined immunodeficiencies	0.019	0.981	0.000
R35 Polyuria	0.000	0.981	0.019
E66.1 Drug-induced obesity	0.019	0.981	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.019	0.981	0.000
D89.3 Immune reconstitution syndrome	0.019	0.981	0.000
E70-E90 Metabolic disorders	0.014	0.981	0.005
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.019	0.981	0.000
S20.7 Multiple superficial injuries of thorax	0.018	0.981	0.000
S20.0 Contusion of breast	0.018	0.981	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.018	0.982	0.000
A04.5 Campylobacter enteritis	0.000	0.982	0.018
D84 Other immunodeficiencies	0.018	0.982	0.000
R47 Speech disturbances, not elsewhere classified	0.018	0.982	0.000
D86.3 Sarcoidosis of skin	0.018	0.982	0.000
A04.4 Other intestinal Escherichia coli infections	0.000	0.983	0.017
S20.4 Other superficial injuries of back wall of thorax	0.017	0.983	0.000
A04.9 Bacterial intestinal infection, unspecified	0.000	0.983	0.017
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.017	0.983	0.000
D50-D53 Nutritional anaemias	0.017	0.983	0.000
E66.0 Obesity due to excess calories	0.016	0.983	0.000
L29.0 Pruritus ani	0.000	0.983	0.017
R47.1 Dysarthria and anarthria	0.016	0.984	0.000
D83.9 Common variable immunodeficiency, unspecified	0.016	0.984	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.016	0.984	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.015	0.985	0.000
D51 Vitamin B12 deficiency anaemia	0.015	0.985	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.000	0.985	0.015
A04.3 Enterohaemorrhagic Escherichia coli infection	0.000	0.985	0.015
A04.2 Enteroinvasive Escherichia coli infection	0.000	0.985	0.015
A04.1 Enterotoxigenic Escherichia coli infection	0.000	0.985	0.015
A04.0 Enteropathogenic Escherichia coli infection	0.000	0.985	0.015
E04.2 Non-toxic multinodular goitre	0.015	0.985	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.015	0.985	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.015	0.985	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.015	0.985	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.015	0.985	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.015	0.985	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.015	0.985	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.015	0.985	0.000
D83.8 Other common variable immunodeficiencies	0.015	0.985	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.015	0.985	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.015	0.985	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.015	0.985	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.985	0.015
D50 Iron deficiency anaemia	0.015	0.985	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.015	0.985	0.000
E73 Lactose intolerance	0.012	0.986	0.003
E84 Cystic fibrosis	0.011	0.986	0.003
D81.9 Combined immunodeficiency, unspecified	0.014	0.986	0.000
D81.8 Other combined immunodeficiencies	0.014	0.986	0.000
D81.7 Major histocompatibility complex class II deficiency	0.014	0.986	0.000
D81.6 Major histocompatibility complex class I deficiency	0.014	0.986	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.014	0.986	0.000
D81.4 Nezelof's syndrome	0.014	0.986	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.014	0.986	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.014	0.986	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.014	0.986	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.014	0.986	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations