TreeWAS – Variant ID: rs2016444

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.240	0.760
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.238	0.762
# Top node	0.234	0.766
Chapter XII Diseases of the skin and subcutaneous tissue	0.233	0.767
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.232	0.768
M25 Other joint disorders, not elsewhere classified	0.228	0.772
M20-M25 Other joint disorders	0.228	0.772
Chapter II Neoplasms	0.225	0.775
L80-L99 Other disorders of the skin and subcutaneous tissue	0.224	0.776
T81 Complications of procedures, not elsewhere classified	0.224	0.776
M25.5 Pain in joint	0.219	0.781
C43-C44 Melanoma and other malignant neoplasms of skin	0.218	0.782
L90 Atrophic disorders of skin	0.217	0.783
Chapter VIII Diseases of the ear and mastoid process	0.214	0.786
C44 Other malignant neoplasms of skin	0.214	0.786
T81.3 Disruption of operation wound, not elsewhere classified	0.213	0.787
T85 Complications of other internal prosthetic devices, implants and grafts	0.213	0.787
Chapter VII Diseases of the eye and adnexa	0.212	0.788
L20-L30 Dermatitis and eczema	0.211	0.789
M50-M54 Other dorsopathies	0.210	0.790
L90.5 Scar conditions and fibrosis of skin	0.209	0.791
M25.57 Pain in joint (Ankle and foot)	0.208	0.792
C60-C63 Malignant neoplasms of male genital organs	0.208	0.792
S00-S09 Injuries to the head	0.204	0.796
S60-S69 Injuries to the wrist and hand	0.203	0.797
M70-M79 Other soft tissue disorders	0.201	0.799
H65-H75 Diseases of middle ear and mastoid	0.201	0.799
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.200	0.800
T88 Other complications of surgical and medical care, not elsewhere classified	0.200	0.800
M25.7 Osteophyte	0.199	0.801
L40-L45 Papulosquamous disorders	0.199	0.801
M54 Dorsalgia	0.198	0.802
S40-S49 Injuries to the shoulder and upper arm	0.198	0.802
M35 Other systemic involvement of connective tissue	0.197	0.803
C61 Malignant neoplasm of prostate	0.196	0.804
S90-S99 Injuries to the ankle and foot	0.195	0.805
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.195	0.805
M22 Disorders of patella	0.194	0.806
M54.5 Low back pain	0.192	0.808
L82 Seborrhoeic keratosis	0.192	0.808
M25.50 Pain in joint (Multiple sites)	0.191	0.809
Chapter IV Endocrine, nutritional and metabolic diseases	0.191	0.809
M25.4 Effusion of joint	0.190	0.810
H53-H54 Visual disturbances and blindness	0.190	0.810
H00 Hordeolum and chalazion	0.189	0.811
C44.0 Skin of lip	0.189	0.811
C44.4 Skin of scalp and neck	0.188	0.812
C44.7 Skin of lower limb, including hip	0.188	0.812
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.187	0.813
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.187	0.813
T86 Failure and rejection of transplanted organs and tissues	0.186	0.814
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.186	0.814
T36-T50 Poisoning by drugs, medicaments and biological substances	0.186	0.814
Chapter XX External causes of morbidity and mortality	0.186	0.814
T81.8 Other complications of procedures, not elsewhere classified	0.186	0.814
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.185	0.815
M25.56 Pain in joint (Lower leg)	0.185	0.815
C15-C26 Malignant neoplasms of digestive organs	0.184	0.816
L89 Decubitus ulcer	0.184	0.816
L90.0 Lichen sclerosus et atrophicus	0.183	0.817
T79-T79 Certain early complications of trauma	0.183	0.817
M79 Other soft tissue disorders, not elsewhere classified	0.182	0.818
M54.59 Low back pain (Site unspecified)	0.182	0.818
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.182	0.818
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.182	0.818
S01 Open wound of head	0.181	0.819
H00.1 Chalazion	0.180	0.820
L00-L08 Infections of the skin and subcutaneous tissue	0.179	0.821
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.179	0.821
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.179	0.821
M35.0 Sicca syndrome [Sjogren]	0.178	0.822
Chapter XV Pregnancy, childbirth and the puerperium	0.178	0.822
L27 Dermatitis due to substances taken internally	0.178	0.822
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.177	0.823
M34 Systemic sclerosis	0.177	0.823
H05 Disorders of orbit	0.177	0.823
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.176	0.824
C44.2 Skin of ear and external auricular canal	0.175	0.825
M79.6 Pain in limb	0.175	0.825
L29 Pruritus	0.175	0.825
M25.6 Stiffness of joint, not elsewhere classified	0.175	0.825
M22.8 Other disorders of patella	0.175	0.825
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.174	0.826
S61 Open wound of wrist and hand	0.173	0.827
H53 Visual disturbances	0.173	0.827
C71 Malignant neoplasm of brain	0.173	0.827
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.172	0.828
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.172	0.828
T33-T35 Frostbite	0.172	0.828
T26-T28 Burns and corrosions confined to eye and internal organs	0.172	0.828
T20-T25 Burns and corrosions of external body surface, specified by site	0.172	0.828
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.172	0.828
T00-T07 Injuries involving multiple body regions	0.172	0.828
S10-S19 Injuries to the neck	0.172	0.828
L40 Psoriasis	0.172	0.828
M80-M85 Disorders of bone density and structure	0.172	0.828
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.171	0.829
T87 Complications peculiar to reattachment and amputation	0.171	0.829
T80 Complications following infusion, transfusion and therapeutic injection	0.171	0.829
M54.57 Low back pain (Lumbosacral region)	0.171	0.829
Chapter XXII Codes for special purposes	0.171	0.829
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.171	0.829
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.170	0.830
M25.75 Osteophyte (Pelvic region and thigh)	0.170	0.830
M05-M14 Inflammatory polyarthropathies	0.169	0.831
L91 Hypertrophic disorders of skin	0.169	0.831
T66-T78 Other and unspecified effects of external causes	0.168	0.832
Chapter XVI Certain conditions originating in the perinatal period	0.168	0.832
C16 Malignant neoplasm of stomach	0.168	0.832
L10-L14 Bullous disorders	0.167	0.833
E20-E35 Disorders of other endocrine glands	0.167	0.833
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.167	0.833
L02 Cutaneous abscess, furuncle and carbuncle	0.167	0.833
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.167	0.833
S01.5 Open wound of lip and oral cavity	0.167	0.833
M91-M94 Chondropathies	0.166	0.834
M60-M63 Disorders of muscles	0.166	0.834
M00-M03 Infectious arthropathies	0.166	0.834
L60-L75 Disorders of skin appendages	0.166	0.834
C44.3 Skin of other and unspecified parts of face	0.166	0.834
M86-M90 Other osteopathies	0.166	0.834
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.166	0.834
H70 Mastoiditis and related conditions	0.165	0.835
L92 Granulomatous disorders of skin and subcutaneous tissue	0.165	0.835
H55-H59 Other disorders of eye and adnexa	0.165	0.835
S05 Injury of eye and orbit	0.165	0.835
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.164	0.835
M40-M43 Deforming dorsopathies	0.164	0.836
M25.9 Joint disorder, unspecified	0.164	0.836
M25.8 Other specified joint disorders	0.164	0.836
M25.3 Other instability of joint	0.164	0.836
M25.2 Flail joint	0.164	0.836
M25.1 Fistula of joint	0.164	0.836
M25.0 Haemarthrosis	0.164	0.836
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.164	0.836
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.164	0.836
M33 Dermatopolymyositis	0.164	0.836
M32 Systemic lupus erythematosus	0.164	0.836
M30 Polyarteritis nodosa and related conditions	0.164	0.836
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.163	0.836
M21 Other acquired deformities of limbs	0.163	0.836
H53.1 Subjective visual disturbances	0.163	0.837
L28 Lichen simplex chronicus and prurigo	0.163	0.837
M25.71 Osteophyte (Shoulder region)	0.163	0.837
M25.53 Pain in joint (Forearm)	0.162	0.838
S91 Open wound of ankle and foot	0.162	0.838
S50-S59 Injuries to the elbow and forearm	0.162	0.838
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.162	0.838
C40-C41 Malignant neoplasms of bone and articular cartilage	0.162	0.838
H66 Suppurative and unspecified otitis media	0.162	0.838
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.161	0.838
H72 Perforation of tympanic membrane	0.161	0.838
T15-T19 Effects of foreign body entering through natural orifice	0.161	0.839
C51-C58 Malignant neoplasms of female genital organs	0.161	0.839
S02 Fracture of skull and facial bones	0.161	0.839
T81.9 Unspecified complication of procedure	0.161	0.839
T81.7 Vascular complications following a procedure, not elsewhere classified	0.161	0.839
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.161	0.839
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.161	0.839
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.161	0.839
L95 Vasculitis limited to skin, not elsewhere classified	0.161	0.839
L94 Other localised connective tissue disorders	0.161	0.839
L93 Lupus erythematosus	0.161	0.839
L87 Transepidermal elimination disorders	0.161	0.839
L88 Pyoderma gangrenosum	0.161	0.839
L86 Keratoderma in diseases classified elsewhere	0.161	0.839
L83 Acanthosis nigricans	0.161	0.839
L80 Vitiligo	0.161	0.839
C64-C68 Malignant neoplasms of urinary tract	0.160	0.839
H80-H83 Diseases of inner ear	0.160	0.840
M31 Other necrotising vasculopathies	0.159	0.840
S60 Superficial injury of wrist and hand	0.159	0.840
C73 Malignant neoplasm of thyroid gland	0.159	0.841
L50-L54 Urticaria and erythema	0.159	0.841
T85.2 Mechanical complication of intraocular lens	0.159	0.841
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.159	0.841
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.159	0.841
S01.1 Open wound of eyelid and periocular area	0.158	0.842
H65 Nonsuppurative otitis media	0.158	0.842
M25.45 Effusion of joint (Pelvic region and thigh)	0.158	0.842
O60-O75 Complications of labour and delivery	0.158	0.842
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.157	0.843
C43 Malignant melanoma of skin	0.157	0.843
M25.74 Osteophyte (Hand)	0.157	0.843
L84 Corns and callosities	0.157	0.843
M25.59 Pain in joint (Site unspecified)	0.157	0.843
M25.58 Pain in joint (Other)	0.157	0.843
M25.54 Pain in joint (Hand)	0.157	0.843
M25.52 Pain in joint (Upper arm)	0.157	0.843
H43-H45 Disorders of vitreous body and globe	0.157	0.843
L90.9 Atrophic disorder of skin, unspecified	0.156	0.844
L90.8 Other atrophic disorders of skin	0.156	0.844
L90.6 Striae atrophicae	0.156	0.844
L90.4 Acrodermatitis chronica atrophicans	0.156	0.844
L90.3 Atrophoderma of Pasini and Pierini	0.156	0.844
L90.2 Anetoderma of Jadassohn-Pellizzari	0.156	0.844
L90.1 Anetoderma of Schweninger-Buzzi	0.156	0.844
H71 Cholesteatoma of middle ear	0.156	0.844
M51 Other intervertebral disk disorders	0.155	0.845
S20-S29 Injuries to the thorax	0.155	0.845
H60-H62 Diseases of external ear	0.155	0.845
D60-D64 Aplastic and other anaemias	0.155	0.845
E00-E07 Disorders of thyroid gland	0.155	0.845
S64 Injury of nerves at wrist and hand level	0.154	0.845
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.154	0.846
S66 Injury of muscle and tendon at wrist and hand level	0.154	0.846
M24 Other specific joint derangements	0.154	0.846
L27.0 Generalised skin eruption due to drugs and medicaments	0.154	0.846
C44.9 Malignant neoplasm of skin, unspecified	0.153	0.847
C44.8 Overlapping lesion of skin	0.153	0.847
S70-S79 Injuries to the hip and thigh	0.153	0.847
L30 Other dermatitis	0.153	0.847
S46 Injury of muscle and tendon at shoulder and upper arm level	0.153	0.847
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.153	0.847
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.153	0.847
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.153	0.847
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.153	0.847
W00-W19 Falls	0.153	0.847
H46-H48 Disorders of optic nerve and visual pathways	0.152	0.848
M75 Shoulder lesions	0.152	0.848
L25 Unspecified contact dermatitis	0.151	0.848
L24 Irritant contact dermatitis	0.151	0.848
L23 Allergic contact dermatitis	0.151	0.848
L21 Seborrhoeic dermatitis	0.151	0.848
L20 Atopic dermatitis	0.151	0.848
L26 Exfoliative dermatitis	0.151	0.848
L22 Diaper [napkin] dermatitis	0.151	0.848
H05.2 Exophthalmic conditions	0.151	0.849
M22.2 Patellofemoral disorders	0.151	0.849
M53 Other dorsopathies, not elsewhere classified	0.151	0.849
H10-H13 Disorders of conjunctiva	0.150	0.850
T88.7 Unspecified adverse effect of drug or medicament	0.150	0.850
C16.0 Cardia	0.150	0.850
T88.4 Failed or difficult intubation	0.149	0.851
C44.1 Skin of eyelid, including canthus	0.149	0.851
C63 Malignant neoplasm of other and unspecified male genital organs	0.149	0.851
C60 Malignant neoplasm of penis	0.149	0.851
M79.65 Pain in limb (Pelvic region and thigh)	0.149	0.851
M54.1 Radiculopathy	0.149	0.851
T86.8 Failure and rejection of other transplanted organs and tissues	0.149	0.851
L43 Lichen planus	0.149	0.851
M25.51 Pain in joint (Shoulder region)	0.149	0.851
L85 Other epidermal thickening	0.149	0.851
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.148	0.852
C71.9 Brain, unspecified	0.148	0.852
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.148	0.852
H73 Other disorders of tympanic membrane	0.148	0.852
H02 Other disorders of eyelid	0.148	0.852
E16 Other disorders of pancreatic internal secretion	0.148	0.852
S61.8 Open wound of other parts of wrist and hand	0.148	0.852
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.147	0.853
M25.76 Osteophyte (Lower leg)	0.147	0.853
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.147	0.853
M54.9 Dorsalgia, unspecified	0.147	0.853
C62 Malignant neoplasm of testis	0.146	0.854
L89.9 Decubitus ulcer and pressure area, unspecified	0.146	0.854
S08 Traumatic amputation of part of head	0.146	0.854
S07 Crushing injury of head	0.146	0.854
S04 Injury of cranial nerves	0.146	0.854
S03 Dislocation, sprain and strain of joints and ligaments of head	0.146	0.854
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.146	0.854
M70 Soft tissue disorders related to use, overuse and pressure	0.146	0.854
M77 Other enthesopathies	0.146	0.854
M25.46 Effusion of joint (Lower leg)	0.145	0.854
S69 Other and unspecified injuries of wrist and hand	0.145	0.854
S67 Crushing injury of wrist and hand	0.145	0.854
S65 Injury of blood vessels at wrist and hand level	0.145	0.854
L40.9 Psoriasis, unspecified	0.145	0.854
S43.0 Dislocation of shoulder joint	0.145	0.855
L89.1 Stage II decubitus ulcer	0.145	0.855
C50-C50 Malignant neoplasm of breast	0.145	0.855
M76 Enthesopathies of lower limb, excluding foot	0.144	0.855
M73 Soft tissue disorders in diseases classified elsewhere	0.144	0.855
M71 Other bursopathies	0.144	0.855
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.144	0.856
H74 Other disorders of middle ear and mastoid	0.144	0.856
H69 Other disorders of Eustachian tube	0.144	0.856
H68 Eustachian salpingitis and obstruction	0.144	0.856
H67 Otitis media in diseases classified elsewhere	0.144	0.856
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.144	0.856
C21 Malignant neoplasm of anus and anal canal	0.144	0.856
T84.0 Mechanical complication of internal joint prosthesis	0.144	0.856
D80-D89 Certain disorders involving the immune mechanism	0.144	0.856
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.144	0.856
H03 Disorders of eyelid in diseases classified elsewhere	0.144	0.856
H20 Iridocyclitis	0.143	0.856
T83.0 Mechanical complication of urinary (indwelling) catheter	0.143	0.857
T88.9 Complication of surgical and medical care, unspecified	0.143	0.857
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.143	0.857
T88.5 Other complications of anaesthesia	0.143	0.857
T88.3 Malignant hyperthermia due to anaesthesis	0.143	0.857
T88.2 Shock due to anaesthesia	0.143	0.857
T88.1 Other complications following immunisation, not elsewhere classified	0.143	0.857
T88.0 Infection following immunisation	0.143	0.857
M79.66 Pain in limb (Lower leg)	0.143	0.857
M25.78 Osteophyte (Other)	0.143	0.857
H90-H95 Other disorders of ear	0.143	0.857
M25.79 Osteophyte (Site unspecified)	0.143	0.857
M25.73 Osteophyte (Forearm)	0.143	0.857
M25.72 Osteophyte (Upper arm)	0.143	0.857
M25.70 Osteophyte (Multiple sites)	0.143	0.857
L44 Other papulosquamous disorders	0.143	0.857
L41 Parapsoriasis	0.143	0.857
L45 Papulosquamous disorders in diseases classified elsewhere	0.143	0.857
L42 Pityriasis rosea	0.143	0.857
H05.0 Acute inflammation of orbit	0.143	0.857
M79.61 Pain in limb (Shoulder region)	0.143	0.857
T79 Certain early complications of trauma, not elsewhere classified	0.142	0.858
M54.8 Other dorsalgia	0.142	0.858
M54.6 Pain in thoracic spine	0.142	0.858
M54.4 Lumbago with sciatica	0.142	0.858
M54.0 Panniculitis affecting regions of neck and back	0.142	0.858
S92 Fracture of foot, except ankle	0.142	0.858
S49 Other and unspecified injuries of shoulder and upper arm	0.142	0.858
S48 Traumatic amputation of shoulder and upper arm	0.142	0.858
S45 Injury of blood vessels at shoulder and upper arm level	0.142	0.858
S44 Injury of nerves at shoulder and upper arm level	0.142	0.858
S41 Open wound of shoulder and upper arm	0.142	0.858
S40 Superficial injury of shoulder and upper arm	0.142	0.858
S47 Crushing injury of shoulder and upper arm	0.142	0.858
L29.0 Pruritus ani	0.142	0.858
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.142	0.858
M35.9 Systemic involvement of connective tissue, unspecified	0.141	0.858
M35.8 Other specified systemic involvement of connective tissue	0.141	0.858
M35.7 Hypermobility syndrome	0.141	0.858
M35.6 Relapsing panniculitis [Weber-Christian]	0.141	0.858
M35.5 Multifocal fibrosclerosis	0.141	0.858
M35.4 Diffuse (eosinophilic) fasciitis	0.141	0.858
M35.2 Behcet's disease	0.141	0.858
M35.1 Other overlap syndromes	0.141	0.858
H00.0 Hordeolum and other deep inflammation of eyelid	0.141	0.859
L81 Other disorders of pigmentation	0.141	0.859
C71.2 Temporal lobe	0.141	0.859
S61.9 Open wound of wrist and hand, part unspecified	0.141	0.859
M79.60 Pain in limb (Multiple sites)	0.141	0.859
M79.1 Myalgia	0.141	0.859
H54 Blindness and low vision	0.141	0.859
T85.4 Mechanical complication of breast prosthesis and implant	0.140	0.860
S99 Other and unspecified injuries of ankle and foot	0.140	0.860
S98 Traumatic amputation of ankle and foot	0.140	0.860
S97 Crushing injury of ankle and foot	0.140	0.860
S96 Injury of muscle and tendon at ankle and foot level	0.140	0.860
S95 Injury of blood vessels at ankle and foot level	0.140	0.860
S94 Injury of nerves at ankle and foot level	0.140	0.860
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.140	0.860
S90 Superficial injury of ankle and foot	0.140	0.860
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.140	0.860
M34.9 Systemic sclerosis, unspecified	0.140	0.860
D50-D53 Nutritional anaemias	0.140	0.860
O63 Long labour	0.140	0.860
H70.9 Mastoiditis, unspecified	0.140	0.860
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.140	0.860
C70 Malignant neoplasm of meninges	0.140	0.860
C69 Malignant neoplasm of eye and adnexa	0.140	0.860
E04 Other non-toxic goitre	0.140	0.860
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.140	0.860
M22.1 Recurrent subluxation of patella	0.139	0.860
M22.9 Disorder of patella, unspecified	0.139	0.860
M22.3 Other derangements of patella	0.139	0.860
M22.0 Recurrent dislocation of patella	0.139	0.860
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.139	0.860
M06 Other rheumatoid arthritis	0.139	0.861
Q60-Q64 Congenital malformations of the urinary system	0.139	0.861
M54.2 Cervicalgia	0.138	0.861
S91.3 Open wound of other parts of foot	0.138	0.862
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.138	0.862
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.138	0.862
S06 Intracranial injury	0.138	0.862
H01 Other inflammation of eyelid	0.137	0.862
M54.55 Low back pain (Thoracolumbar region)	0.137	0.862
M54.54 Low back pain-Thoracic	0.137	0.862
M54.53 Low back pain-Cervicothoracic	0.137	0.862
M54.52 Low back pain-Cervical	0.137	0.862
M54.51 Low back pain-Occipit-atl-axl	0.137	0.862
M54.50 Low back pain (Multiple sites in spine)	0.137	0.862
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.137	0.862
E40-E46 Malnutrition	0.137	0.863
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.137	0.863
C16.9 Stomach, unspecified	0.137	0.863
S05.8 Other injuries of eye and orbit	0.137	0.863
M25.49 Effusion of joint (Site unspecified)	0.137	0.863
M25.48 Effusion of joint (Other)	0.137	0.863
M25.47 Effusion of joint (Ankle and foot)	0.137	0.863
M25.44 Effusion of joint (Hand)	0.137	0.863
M25.43 Effusion of joint (Forearm)	0.137	0.863
M25.42 Effusion of joint (Upper arm)	0.137	0.863
M25.41 Effusion of joint (Shoulder region)	0.137	0.863
M25.40 Effusion of joint (Multiple sites)	0.137	0.863
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.136	0.863
S32 Fracture of lumbar spine and pelvis	0.136	0.863
L29.9 Pruritus, unspecified	0.136	0.864
T83.3 Mechanical complication of intra-uterine contraceptive device	0.136	0.864
T31 Burns classified according to extent of body surface involved	0.135	0.864
E27 Other disorders of adrenal gland	0.135	0.865
M79.5 Residual foreign body in soft tissue	0.135	0.865
E23 Hypofunction and other disorders of pituitary gland	0.135	0.865
S61.7 Multiple open wounds of wrist and hand	0.135	0.865
E16.2 Hypoglycaemia, unspecified	0.135	0.865
D37-D48 Neoplasms of uncertain or unknown behaviour	0.135	0.865
M79.67 Pain in limb (Ankle and foot)	0.135	0.865
W20-W49 Exposure to inanimate mechanical forces	0.135	0.865
L40.0 Psoriasis vulgaris	0.135	0.865
S80-S89 Injuries to the knee and lower leg	0.134	0.865
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.134	0.866
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.134	0.866
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.134	0.866
T84.3 Mechanical complication of other bone devices, implants and grafts	0.134	0.866
M79.63 Pain in limb (Forearm)	0.134	0.866
L73 Other follicular disorders	0.134	0.866
C75 Malignant neoplasm of other endocrine glands and related structures	0.134	0.866
C74 Malignant neoplasm of adrenal gland	0.134	0.866
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.134	0.866
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.134	0.866
T86.4 Liver transplant failure and rejection	0.134	0.866
T86.3 Heart-lung transplant failure and rejection	0.134	0.866
T86.2 Heart transplant failure and rejection	0.134	0.866
T86.1 Kidney transplant failure and rejection	0.134	0.866
T86.0 Bone-marrow transplant rejection	0.134	0.866
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.134	0.866
S37 Injury of urinary and pelvic organs	0.134	0.866
S36 Injury of intra-abdominal organs	0.134	0.866
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.134	0.866
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.134	0.866
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.134	0.866
S31 Open wound of abdomen, lower back and pelvis	0.134	0.866
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.133	0.866
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.133	0.866
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.133	0.866
T46 Poisoning by agents primarily affecting the cardiovascular system	0.133	0.866
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.133	0.866
T41 Poisoning by anaesthetics and therapeutic gases	0.133	0.866
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.133	0.866
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.133	0.866
T36 Poisoning by systemic antibiotics	0.133	0.866
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.133	0.866
Y35-Y36 Legal intervention and operations of war	0.133	0.866
Y10-Y34 Event of undetermined intent	0.133	0.866
Y00-Y09 Assault	0.133	0.866
X85-X99 Assault	0.133	0.866
X58-X59 Accidental exposure to other and unspecified factors	0.133	0.866
X50-X57 Overexertion, travel and privation	0.133	0.866
X40-X49 Accidental poisoning by and exposure to noxious substances	0.133	0.866
X30-X39 Exposure to forces of nature	0.133	0.866
X20-X29 Contact with venomous animals and plants	0.133	0.866
X10-X19 Contact with heat and hot substances	0.133	0.866
X00-X09 Exposure to smoke, fire and flames	0.133	0.866
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.133	0.866
W75-W84 Other accidental threats to breathing	0.133	0.866
W65-W74 Accidental drowning and submersion	0.133	0.866
W50-W64 Exposure to animate mechanical forces	0.133	0.866
V98-V99 Other and unspecified transport accidents	0.133	0.866
V95-V97 Air and space transport accidents	0.133	0.866
V90-V94 Water transport accidents	0.133	0.866
V80-V89 Other land transport accidents	0.133	0.866
V70-V79 Bus occupant injured in transport accident	0.133	0.866
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.133	0.866
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.133	0.866
V40-V49 Car occupant injured in transport accident	0.133	0.866
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.133	0.866
V01-V09 Pedestrian injured in transport accident	0.133	0.866
M65-M68 Disorders of synovium and tendon	0.133	0.867
Y43 Primarily systemic agents	0.133	0.867
M35.3 Polymyalgia rheumatica	0.133	0.867
S30 Superficial injury of abdomen, lower back and pelvis	0.133	0.867
H72.9 Perforation of tympanic membrane, unspecified	0.133	0.867
D55-D59 Haemolytic anaemias	0.133	0.867
X60-X84 Intentional self-harm	0.133	0.867
C44.5 Skin of trunk	0.133	0.867
E29 Testicular dysfunction	0.133	0.867
C22.9 Liver, unspecified	0.133	0.867
C26 Malignant neoplasm of other and ill-defined digestive organs	0.132	0.868
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.132	0.868
C17 Malignant neoplasm of small intestine	0.132	0.868
C23 Malignant neoplasm of gallbladder	0.132	0.868
L89.3 Stage IV decubitus ulcer	0.132	0.868
L89.2 Stage III decubitus ulcer	0.132	0.868
L89.0 Stage I decubitus ulcer and pressure area	0.132	0.868
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.132	0.868
C44.6 Skin of upper limb, including shoulder	0.132	0.868
L97 Ulcer of lower limb, not elsewhere classified	0.132	0.868
S02.2 Fracture of nasal bones	0.131	0.868
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.131	0.869
M79.9 Soft tissue disorder, unspecified	0.131	0.869
M79.4 Hypertrophy of (infrapatellar) fat pad	0.131	0.869
M79.3 Panniculitis, unspecified	0.131	0.869
M79.2 Neuralgia and neuritis, unspecified	0.131	0.869
H55 Nystagmus and other irregular eye movements	0.131	0.869
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.131	0.869
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.131	0.869
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.131	0.869
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.131	0.869
T83.2 Mechanical complication of graft of urinary organ	0.131	0.869
T83.1 Mechanical complication of other urinary devices and implants	0.131	0.869
O94-O99 Other obstetric conditions, not elsewhere classified	0.131	0.869
C83 Diffuse non-Hodgkin's lymphoma	0.131	0.869
O66 Other obstructed labour	0.131	0.869
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.131	0.869
L60 Nail disorders	0.131	0.869
S68 Traumatic amputation of wrist and hand	0.130	0.869
S42 Fracture of shoulder and upper arm	0.130	0.870

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations