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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2022084
log Bayes Factor = 56.4296
Chromosome 6   position 31,117,053  (GRCh37) Explore rs2022084 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
G35 Multiple sclerosis
0.987 0.013 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.017 0.983
E70-E90 Metabolic disorders
0.000 0.021 0.979
L40 Psoriasis
0.000 0.050 0.950
E14 Unspecified diabetes mellitus
0.000 0.072 0.928
L40.5 Arthropathic psoriasis
0.000 0.114 0.886
E11.0 With coma
0.000 0.116 0.884
E78.8 Other disorders of lipoprotein metabolism
0.000 0.127 0.873
E07 Other disorders of thyroid
0.000 0.143 0.857
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.157 0.843
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.161 0.839
E14.3 With ophthalmic complications
0.000 0.161 0.839
E78.2 Mixed hyperlipidaemia
0.000 0.165 0.834
E10.3 With ophthalmic complications
0.000 0.168 0.832
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.182 0.818
L40.0 Psoriasis vulgaris
0.000 0.190 0.810
E03.8 Other specified hypothyroidism
0.000 0.191 0.809
G35-G37 Demyelinating diseases of the central nervous system
0.778 0.222 0.000
L40.8 Other psoriasis
0.000 0.224 0.776
E11.1 With ketoacidosis
0.000 0.226 0.774
E79 Disorders of purine and pyrimidine metabolism
0.000 0.233 0.767
E74 Other disorders of carbohydrate metabolism
0.000 0.235 0.765
E07.9 Disorder of thyroid, unspecified
0.000 0.235 0.765
E78.4 Other hyperlipidaemia
0.000 0.236 0.764
E11.2 With renal complications
0.000 0.243 0.757
E10.6 With other specified complications
0.000 0.244 0.756
E10.8 With unspecified complications
0.000 0.247 0.753
E78.1 Pure hyperglyceridaemia
0.000 0.253 0.747
E14.5 With peripheral circulatory complications
0.000 0.267 0.733
E78.5 Hyperlipidaemia, unspecified
0.000 0.273 0.727
L40.1 Generalised pustular psoriasis
0.000 0.274 0.726
E14.9 Without complications
0.000 0.275 0.725
E10.1 With ketoacidosis
0.000 0.276 0.724
G37 Other demyelinating diseases of central nervous system
0.721 0.279 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.716
E10.0 With coma
0.000 0.288 0.712
E05.5 Thyroid crisis or storm
0.000 0.289 0.711
E05.4 Thyrotoxicosis factitia
0.000 0.289 0.711
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.289 0.711
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.289 0.711
E78.6 Lipoprotein deficiency
0.000 0.292 0.707
E78.3 Hyperchylomicronaemia
0.000 0.295 0.705
E13 Other specified diabetes mellitus
0.000 0.297 0.703
E77 Disorders of glycoprotein metabolism
0.000 0.298 0.702
E76 Disorders of glycosaminoglycan metabolism
0.000 0.298 0.702
E72 Other disorders of amino-acid metabolism
0.000 0.298 0.702
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.702
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.298 0.702
K90 Intestinal malabsorption
0.000 0.300 0.700
E40-E46 Malnutrition
0.000 0.306 0.693
E14.4 With neurological complications
0.000 0.307 0.693
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.308 0.692
E80.4 Gilbert's syndrome
0.000 0.311 0.689
E16 Other disorders of pancreatic internal secretion
0.000 0.312 0.688
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.313 0.686
L40.2 Acrodermatitis continua
0.000 0.319 0.681
E84 Cystic fibrosis
0.000 0.323 0.676
L40.4 Guttate psoriasis
0.000 0.324 0.676
E14.6 With other specified complications
0.000 0.329 0.671
E14.1 With ketoacidosis
0.000 0.331 0.669
E14.7 With multiple complications
0.000 0.335 0.665
E14.0 With coma
0.000 0.335 0.665
E80.6 Other disorders of bilirubin metabolism
0.000 0.336 0.664
G37.9 Demyelinating disease of central nervous system, unspecified
0.664 0.336 0.000
E14.2 Withrenal complications
0.000 0.341 0.659
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.354 0.645
E80.2 Other porphyria
0.000 0.356 0.644
E03.1 Congenital hypothyroidism without goitre
0.000 0.365 0.635
E83 Disorders of mineral metabolism
0.592 0.367 0.042
E11.8 With unspecified complications
0.000 0.370 0.630
E14.8 With unspecified complications
0.000 0.373 0.627
E05.8 Other thyrotoxicosis
0.000 0.377 0.623
E10.2 With renal complications
0.000 0.379 0.621
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.385 0.615
E07.1 Dyshormogenetic goitre
0.000 0.385 0.615
E07.0 Hypersecretion of calcitonin
0.000 0.385 0.615
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.385 0.615
G36 Other acute disseminated demyelination
0.613 0.387 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.396 0.604
E80.5 Crigler-Najjar syndrome
0.000 0.396 0.604
E80.3 Defects of catalase and peroxydase
0.000 0.396 0.604
E80.0 Hereditary erythropoietic porphyria
0.000 0.396 0.604
E80.1 Porphyria cutanea tarda
0.000 0.400 0.600
E07.8 Other specified disorders of thyroid
0.000 0.410 0.589
E15 Nondiabetic hypoglycaemic coma
0.000 0.413 0.587
L40-L45 Papulosquamous disorders
0.000 0.414 0.586
E10.5 With peripheral circulatory complications
0.000 0.416 0.584
G37.8 Other specified demyelinating diseases of central nervous system
0.580 0.420 0.000
E88 Other metabolic disorders
0.000 0.423 0.577
E16.2 Hypoglycaemia, unspecified
0.000 0.424 0.576
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.438 0.562
L40.3 Pustulosis palmaris et plantaris
0.000 0.441 0.559
M06.9 Rheumatoid arthritis, unspecified
0.000 0.441 0.559
E73 Lactose intolerance
0.000 0.443 0.557
E11.5 With peripheral circulatory complications
0.000 0.443 0.557
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.450 0.550
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.450 0.550
E79.1 Lesch-Nyhan syndrome
0.000 0.450 0.550
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.451 0.549
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.451 0.549
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.451 0.549
E74.2 Disorders of galactose metabolism
0.000 0.451 0.549
E74.1 Disorders of fructose metabolism
0.000 0.451 0.549
K90.9 Intestinal malabsorption, unspecified
0.000 0.452 0.548
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.478 0.522
E16.1 Other hypoglycaemia
0.000 0.479 0.520
E10.4 With neurological complications
0.000 0.481 0.519
G37.5 Concentric sclerosis [Balo]
0.517 0.483 0.000
G37.4 Subacute necrotising myelitis
0.517 0.483 0.000
G37.2 Central pontine myelinolysis
0.517 0.483 0.000
G37.1 Central demyelination of corpus callosum
0.517 0.483 0.000
G37.0 Diffuse sclerosis
0.517 0.483 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13.9 Without complications
0.000 0.486 0.514
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.511 0.489 0.000
E13.8 With unspecified complications
0.000 0.496 0.504
E13.7 With multiple complications
0.000 0.496 0.504
E13.6 With other specified complications
0.000 0.496 0.504
E13.5 With peripheral circulatory complications
0.000 0.496 0.504
E13.4 With neurological complications
0.000 0.496 0.504
E13.2 With renal complications
0.000 0.496 0.504
E13.1 With ketoacidosis
0.000 0.496 0.504
E13.0 With coma
0.000 0.496 0.504
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.496 0.503
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.496 0.503
E70.3 Albinism
0.000 0.496 0.503
E70.2 Disorders of tyrosine metabolism
0.000 0.496 0.503
E70.1 Other hyperphenylalaninaemias
0.000 0.496 0.503
E70.0 Classical phenylketonuria
0.000 0.496 0.503
E71.3 Disorders of fatty-acid metabolism
0.000 0.496 0.503
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.496 0.503
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.496 0.503
E71.0 Maple-syrup-urine disease
0.000 0.496 0.503
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.496 0.503
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.496 0.503
E72.5 Disorders of glycine metabolism
0.000 0.496 0.503
E72.4 Disorders of ornithine metabolism
0.000 0.496 0.503
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.496 0.503
E72.2 Disorders of urea cycle metabolism
0.000 0.496 0.503
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.496 0.503
E72.0 Disorders of amino-acid transport
0.000 0.496 0.503
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.496 0.503
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.496 0.503
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.496 0.503
E76.2 Other mucopolysaccharidoses
0.000 0.496 0.503
E76.1 Mucopolysaccharidosis, type II
0.000 0.496 0.503
E76.0 Mucopolysaccharidosis, type I
0.000 0.496 0.503
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.496 0.503
E77.8 Other disorders of glycoprotein metabolism
0.000 0.496 0.503
E77.1 Defects in glycoprotein degradation
0.000 0.496 0.503
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.496 0.503
K90.8 Other intestinal malabsorption
0.000 0.497 0.503
K90.3 Pancreatic steatorrhoea
0.000 0.498 0.502
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.498 0.502
K90.1 Tropical sprue
0.000 0.498 0.502
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.499 0.501
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.500 0.500
E83.3 Disorders of phosphorus metabolism
0.484 0.503 0.014
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.503 0.497
E45 Retarded development following protein-energy malnutrition
0.000 0.503 0.497
E43 Unspecified severe protein-energy malnutrition
0.000 0.503 0.497
E42 Marasmic kwashiorkor
0.000 0.503 0.497
E41 Nutritional marasmus
0.000 0.503 0.497
E40 Kwashiorkor
0.000 0.503 0.497
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.503 0.497
G36.0 Neuromyelitis optica [Devic]
0.495 0.505 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.507 0.493
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.507 0.493
E16.4 Abnormal secretion of gastrin
0.000 0.507 0.493
E16.3 Increased secretion of glucagon
0.000 0.507 0.493
E75.6 Lipid storage disorder, unspecified
0.000 0.508 0.492
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.508 0.492
E75.3 Sphingolipidosis, unspecified
0.000 0.508 0.492
E75.2 Other sphingolipidosis
0.000 0.508 0.492
E75.1 Other gangliosidosis
0.000 0.508 0.492
E75.0 GM2 gangliosidosis
0.000 0.508 0.492
L43 Lichen planus
0.000 0.510 0.490
E74.0 Glycogen storage disease
0.000 0.512 0.488
E11.6 With other specified complications
0.000 0.514 0.486
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.485
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.515 0.485
E83.9 Disorder of mineral metabolism, unspecified
0.458 0.515 0.027
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.520 0.480
E13.3 With ophthalmic complications
0.000 0.521 0.479
E75.5 Other lipid storage disorders
0.000 0.523 0.477
E46 Unspecified protein-energy malnutrition
0.000 0.526 0.474
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.534 0.466
E84.9 Cystic fibrosis, unspecified
0.000 0.540 0.459
L42 Pityriasis rosea
0.000 0.542 0.458
E83.8 Other disorders of mineral metabolism
0.424 0.546 0.030
E83.2 Disorders of zinc metabolism
0.424 0.546 0.030
E83.0 Disorders of copper metabolism
0.424 0.546 0.030
E11.4 With neurological complications
0.000 0.547 0.453
E88.2 Lipomatosis, not elsewhere classified
0.000 0.548 0.452
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.553 0.447
L43.9 Lichen planus, unspecified
0.000 0.554 0.446
E85 Amyloidosis
0.000 0.560 0.439
G36.9 Acute disseminated demyelination, unspecified
0.440 0.560 0.000
G36.8 Other specified acute disseminated demyelination
0.440 0.560 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.440 0.560 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.569 0.431
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.575 0.425
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.578 0.422
L44 Other papulosquamous disorders
0.000 0.580 0.420
L41 Parapsoriasis
0.000 0.580 0.420
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.580 0.420
E88.9 Metabolic disorder, unspecified
0.000 0.586 0.414
E88.8 Other specified metabolic disorders
0.000 0.586 0.414
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.588 0.412
E88.3 Tumour lysis syndrome
0.000 0.590 0.409
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.599 0.401
E73.8 Other lactose intolerance
0.000 0.600 0.399
E73.1 Secondary lactase deficiency
0.000 0.600 0.399
E73.0 Congenital lactase deficiency
0.000 0.600 0.399
E89.4 Postprocedural ovarian failure
0.000 0.606 0.394
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.616 0.383
E06 Thyroiditis
0.000 0.620 0.379
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.628 0.372
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.629 0.371
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.629 0.371
E89.5 Postprocedural testicular hypofunction
0.000 0.629 0.371
E89.1 Postprocedural hypoinsulinaemia
0.000 0.629 0.371
E44.1 Mild protein-energy malnutrition
0.000 0.643 0.357
E44.0 Moderate protein-energy malnutrition
0.000 0.643 0.357
L43.3 Subacute (active) lichen planus
0.000 0.648 0.351
L43.2 Lichenoid drug reaction
0.000 0.648 0.351
L43.1 Bullous lichen planus
0.000 0.648 0.351
L43.0 Hypertrophic lichen planus
0.000 0.648 0.351
E89.3 Postprocedural hypopituitarism
0.000 0.656 0.344
E65-E68 Obesity and other hyperalimentation
0.000 0.668 0.332
E83.4 Disorders of magnesium metabolism
0.304 0.680 0.016
E89.2 Postprocedural hypoparathyroidism
0.000 0.683 0.316
E20-E35 Disorders of other endocrine glands
0.000 0.684 0.316
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.684 0.315
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.684 0.315
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.684 0.315
E83.5 Disorders of calcium metabolism
0.303 0.693 0.004
L41.9 Parapsoriasis, unspecified
0.000 0.698 0.301
L41.8 Other parapsoriasis
0.000 0.698 0.301
L41.5 Retiform parapsoriasis
0.000 0.698 0.301
L41.4 Large plaque parapsoriasis
0.000 0.698 0.301
L41.3 Small plaque parapsoriasis
0.000 0.698 0.301
L41.2 Lymphomatoid papulosis
0.000 0.698 0.301
L41.1 Pityriasis lichenoides chronica
0.000 0.698 0.301
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.698 0.301
L44.9 Papulosquamous disorder, unspecified
0.000 0.698 0.301
L44.8 Other specified papulosquamous disorders
0.000 0.698 0.301
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.698 0.301
L44.3 Lichen ruber moniliformis
0.000 0.698 0.301
L44.2 Lichen striatus
0.000 0.698 0.301
L44.1 Lichen nitidus
0.000 0.698 0.301
L44.0 Pityriasis rubra pilaris
0.000 0.698 0.301
E85.8 Other amyloidosis
0.001 0.700 0.300
C83.3 Large cell (diffuse)
0.000 0.701 0.299
E85.9 Amyloidosis, unspecified
0.000 0.703 0.297
E50-E64 Other nutritional deficiencies
0.000 0.706 0.293
E28 Ovarian dysfunction
0.000 0.719 0.281
L43.8 Other lichen planus
0.000 0.725 0.274
E06.5 Other chronic thyroiditis
0.000 0.727 0.272
E06.4 Drug-induced thyroiditis
0.000 0.727 0.272
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.727 0.272
E06.0 Acute thyroiditis
0.000 0.727 0.272
E28.2 Polycystic ovarian syndrome
0.000 0.734 0.266
E06.1 Subacute thyroiditis
0.001 0.741 0.259
M06 Other rheumatoid arthritis
0.000 0.741 0.259
E85.4 Organ-limited amyloidosis
0.001 0.744 0.256
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.744 0.256
E73.9 Lactose intolerance, unspecified
0.001 0.745 0.254
E23 Hypofunction and other disorders of pituitary gland
0.000 0.749 0.251
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.754 0.246
E11.3 With ophthalmic complications
0.000 0.754 0.246
E24 Cushing's syndrome
0.000 0.756 0.244
E67 Other hyperalimentation
0.000 0.762 0.238
E68 Sequelae of hyperalimentation
0.000 0.762 0.238
E85.3 Secondary systemic amyloidosis
0.001 0.763 0.236
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.763 0.236
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.773 0.227
E32 Diseases of thymus
0.000 0.773 0.227
E31 Polyglandular dysfunction
0.000 0.773 0.227
E30 Disorders of puberty, not elsewhere classified
0.000 0.773 0.227
E25 Adrenogenital disorders
0.000 0.773 0.227
M06.3 Rheumatoid nodule
0.000 0.779 0.221
E21.3 Hyperparathyroidism, unspecified
0.000 0.779 0.221
E26 Hyperaldosteronism
0.000 0.787 0.213
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.789 0.210
E63 Other nutritional deficiencies
0.000 0.789 0.210
E50 Vitamin A deficiency
0.000 0.789 0.210
E60 Dietary zinc deficiency
0.000 0.789 0.210
E59 Dietary selenium deficiency
0.000 0.789 0.210
E54 Ascorbic acid deficiency
0.000 0.789 0.210
E52 Niacin deficiency [pellagra]
0.000 0.789 0.210
E56 Other vitamin deficiencies
0.000 0.793 0.206
E23.7 Disorder of pituitary gland, unspecified
0.000 0.795 0.205
E58 Dietary calcium deficiency
0.000 0.796 0.204
E28.9 Ovarian dysfunction, unspecified
0.000 0.798 0.202
E28.8 Other ovarian dysfunction
0.000 0.798 0.202
E28.1 Androgen excess
0.000 0.798 0.202
E28.0 Oestrogen excess
0.000 0.798 0.202
E23.2 Diabetes insipidus
0.000 0.800 0.200
E51 Thiamine deficiency
0.000 0.803 0.197
E61 Deficiency of other nutrient elements
0.000 0.806 0.194
M06.4 Inflammatory polyarthropathy
0.000 0.809 0.191
E24.2 Drug-induced Cushing's syndrome
0.000 0.811 0.189
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.812 0.188
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.813 0.187
E20 Hypoparathyroidism
0.000 0.814 0.186
M06.2 Rheumatoid bursitis
0.000 0.814 0.186
M06.1 Adult-onset Still's disease
0.000 0.814 0.186
M06.34 Rheumatoid nodule (Hand)
0.000 0.817 0.183
M06.8 Other specified rheumatoid arthritis
0.000 0.817 0.182
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.818 0.182
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.820 0.180
E23.1 Drug-induced hypopituitarism
0.000 0.820 0.180
E06.3 Autoimmune thyroiditis
0.000 0.820 0.179
E24.9 Cushing's syndrome, unspecified
0.000 0.821 0.179
E21.4 Other specified disorders of parathyroid gland
0.000 0.823 0.177
E21.2 Other hyperparathyroidism
0.000 0.823 0.177
E65 Localised adiposity
0.000 0.824 0.176
E29 Testicular dysfunction
0.000 0.824 0.175
E24.8 Other Cushing's syndrome
0.000 0.825 0.175
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.825 0.175
E24.3 Ectopic ACTH syndrome
0.000 0.825 0.175
E24.1 Nelson's syndrome
0.000 0.825 0.175
E24.0 Pituitary-dependent Cushing's disease
0.000 0.825 0.175
E67.8 Other specified hyperalimentation
0.000 0.829 0.171
E67.3 Hypervitaminosis D
0.000 0.829 0.171
E67.2 Megavitamin-B6 syndrome
0.000 0.829 0.171
E67.1 Hypercarotenaemia
0.000 0.829 0.171
E67.0 Hypervitaminosis A
0.000 0.829 0.171
E23.0 Hypopituitarism
0.000 0.832 0.168
E23.6 Other disorders of pituitary gland
0.000 0.832 0.168
E06.9 Thyroiditis, unspecified
0.001 0.833 0.166
E25.9 Adrenogenital disorder, unspecified
0.000 0.837 0.163
E25.8 Other adrenogenital disorders
0.000 0.837 0.163
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.837 0.163
E30.9 Disorder of puberty, unspecified
0.000 0.837 0.163
E30.8 Other disorders of puberty
0.000 0.837 0.163
E30.1 Precocious puberty
0.000 0.837 0.163
E30.0 Delayed puberty
0.000 0.837 0.163
E31.9 Polyglandular dysfunction, unspecified
0.000 0.837 0.163
E31.8 Other polyglandular dysfunction
0.000 0.837 0.163
E31.1 Polyglandular hyperfunction
0.000 0.837 0.163
E31.0 Autoimmune polyglandular failure
0.000 0.837 0.163
E32.9 Disease of thymus, unspecified
0.000 0.837 0.163
E32.8 Other diseases of thymus
0.000 0.837 0.163
E32.1 Abscess of thymus
0.000 0.837 0.163
E32.0 Persistent hyperplasia of thymus
0.000 0.837 0.163
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.837 0.163
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.837 0.163
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.837 0.163
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.841 0.159
M06.38 Rheumatoid nodule (Other)
0.000 0.841 0.159
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.841 0.159
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.841 0.159
M06.33 Rheumatoid nodule (Forearm)
0.000 0.841 0.159
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.841 0.159
E55 Vitamin D deficiency
0.000 0.841 0.158
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.842 0.158
E28.3 Primary ovarian failure
0.000 0.843 0.157
E22 Hyperfunction of pituitary gland
0.000 0.843 0.156
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.846 0.153
E26.9 Hyperaldosteronism, unspecified
0.000 0.847 0.153
E26.8 Other hyperaldosteronism
0.000 0.847 0.153
E26.1 Secondary hyperaldosteronism
0.000 0.847 0.153
E50.9 Vitamin A deficiency, unspecified
0.000 0.849 0.151
E50.8 Other manifestations of vitamin A deficiency
0.000 0.849 0.151
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.849 0.151
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.849 0.151
E50.5 Vitamin A deficiency with night blindness
0.000 0.849 0.151
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.849 0.151
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.849 0.151
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.849 0.151
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.849 0.151
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.849 0.151
E63.9 Nutritional deficiency, unspecified
0.000 0.849 0.151
E63.8 Other specified nutritional deficiencies
0.000 0.849 0.151
E63.1 Imbalance of constituents of food intake
0.000 0.849 0.151
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.849 0.151
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.849 0.151
E64.8 Sequelae of other nutritional deficiencies
0.000 0.849 0.151
E64.3 Sequelae of rickets
0.000 0.849 0.151
E64.2 Sequelae of vitamin C deficiency
0.000 0.849 0.151
E64.1 Sequelae of vitamin A deficiency
0.000 0.849 0.151
E64.0 Sequelae of protein-energy malnutrition
0.000 0.849 0.151
E56.9 Vitamin deficiency, unspecified
0.000 0.852 0.148
E56.8 Deficiency of other vitamins
0.000 0.852 0.148
E56.0 Deficiency of vitamin E
0.000 0.852 0.148
E56.1 Deficiency of vitamin K
0.000 0.856 0.144
E51.9 Thiamine deficiency, unspecified
0.000 0.858 0.141
E51.8 Other manifestations of thiamine deficiency
0.000 0.858 0.141
E51.1 Beriberi
0.000 0.858 0.141
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.859 0.141
E26.0 Primary hyperaldosteronism
0.000 0.860 0.140
E61.9 Deficiency of nutrient element, unspecified
0.000 0.861 0.139
E61.8 Deficiency of other specified nutrient elements
0.000 0.861 0.139
E61.7 Deficiency of multiple nutrient elements
0.000 0.861 0.139
E61.6 Vanadium deficiency
0.000 0.861 0.139
E61.5 Molybdenum deficiency
0.000 0.861 0.139
E61.4 Chromium deficiency
0.000 0.861 0.139
E61.3 Manganese deficiency
0.000 0.861 0.139
E61.0 Copper deficiency
0.000 0.861 0.139
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.863 0.137
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.863 0.137
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.863 0.137
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.863 0.137
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.863 0.137
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.863 0.137
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.863 0.137
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.863 0.137
M06.0 Seronegative rheumatoid arthritis
0.000 0.863 0.137
E20.8 Other hypoparathyroidism
0.000 0.866 0.134
E20.1 Pseudohypoparathyroidism
0.000 0.866 0.134
E20.0 Idiopathic hypoparathyroidism
0.000 0.866 0.134
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.866 0.134
M06.18 Adult-onset Still's disease (Other)
0.000 0.866 0.134
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.866 0.134
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.866 0.134
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.866 0.134
M06.14 Adult-onset Still's disease (Hand)
0.000 0.866 0.134
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.866 0.134
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.866 0.134
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.866 0.134
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.866 0.134
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.866 0.134
M06.28 Rheumatoid bursitis (Other)
0.000 0.866 0.134
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.866 0.134
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.866 0.134
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.866 0.134
M06.24 Rheumatoid bursitis (Hand)
0.000 0.866 0.134
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.866 0.134
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.866 0.134
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.866 0.134
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.866 0.134
E89.0 Postprocedural hypothyroidism
0.000 0.867 0.133
E61.1 Iron deficiency
0.000 0.868 0.132
E61.2 Magnesium deficiency
0.000 0.869 0.131
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.869 0.131
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.869 0.131
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.869 0.131
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.869 0.131
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.869 0.131
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.869 0.131
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.869 0.131
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.869 0.131
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.869 0.131
E51.2 Wernicke's encephalopathy
0.000 0.872 0.128
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.873 0.127
E29.9 Testicular dysfunction, unspecified
0.000 0.874 0.126
E29.8 Other testicular dysfunction
0.000 0.874 0.126
E29.0 Testicular hyperfunction
0.000 0.874 0.126
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.879 0.121
E55.0 Rickets, active
0.000 0.886 0.114
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.887 0.112
E22.8 Other hyperfunction of pituitary gland
0.000 0.887 0.112
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.893 0.106
E22.1 Hyperprolactinaemia
0.000 0.894 0.105
K91.4 Colostomy and enterostomy malfunction
0.104 0.896 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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