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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs203884
log Bayes Factor = 83.3442
Chromosome 6   position 28,077,374  (GRCh37) Explore rs203884 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E10.3 With ophthalmic complications
0.993 0.007 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.992 0.008 0.000
E14 Unspecified diabetes mellitus
0.992 0.008 0.000
K40 Inguinal hernia
0.000 0.009 0.991
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.010 0.990
E16 Other disorders of pancreatic internal secretion
0.988 0.012 0.000
E16.2 Hypoglycaemia, unspecified
0.983 0.017 0.000
E00-E07 Disorders of thyroid gland
0.981 0.019 0.000
E20-E35 Disorders of other endocrine glands
0.972 0.028 0.000
E27 Other disorders of adrenal gland
0.958 0.042 0.000
N40 Hyperplasia of prostate
0.000 0.044 0.956
E14.9 Without complications
0.955 0.045 0.000
E10.1 With ketoacidosis
0.954 0.046 0.000
E27.1 Primary adrenocortical insufficiency
0.953 0.047 0.000
N41 Inflammatory diseases of prostate
0.000 0.055 0.945
E05 Thyrotoxicosis [hyperthyroidism]
0.943 0.057 0.000
N40-N51 Diseases of male genital organs
0.000 0.058 0.942
E03 Other hypothyroidism
0.933 0.067 0.000
E05.9 Thyrotoxicosis, unspecified
0.933 0.067 0.000
N41.0 Acute prostatitis
0.000 0.067 0.933
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.074 0.926
E14.3 With ophthalmic complications
0.925 0.075 0.000
E03.9 Hypothyroidism, unspecified
0.908 0.092 0.000
E10.4 With neurological complications
0.886 0.114 0.000
E07 Other disorders of thyroid
0.875 0.125 0.000
E23 Hypofunction and other disorders of pituitary gland
0.853 0.147 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.853 0.147 0.000
E10.2 With renal complications
0.848 0.152 0.000
E14.4 With neurological complications
0.842 0.158 0.000
N41.1 Chronic prostatitis
0.000 0.164 0.836
N46 Male infertility
0.000 0.172 0.828
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.174 0.826
E24 Cushing's syndrome
0.811 0.189 0.000
K90 Intestinal malabsorption
0.810 0.189 0.000
E20 Hypoparathyroidism
0.809 0.191 0.000
N42 Other disorders of prostate
0.000 0.194 0.806
E10.6 With other specified complications
0.782 0.218 0.000
E10.0 With coma
0.773 0.227 0.000
E50-E64 Other nutritional deficiencies
0.765 0.235 0.000
E23.2 Diabetes insipidus
0.758 0.242 0.000
N44 Torsion of testis
0.000 0.243 0.757
E31 Polyglandular dysfunction
0.756 0.244 0.000
E07.9 Disorder of thyroid, unspecified
0.753 0.247 0.000
E10.7 With multiple complications
0.750 0.250 0.000
E27.9 Disorder of adrenal gland, unspecified
0.743 0.257 0.000
E14.1 With ketoacidosis
0.739 0.261 0.000
E10.5 With peripheral circulatory complications
0.732 0.268 0.000
N42.8 Other specified disorders of prostate
0.000 0.269 0.731
E25 Adrenogenital disorders
0.729 0.270 0.000
E27.2 Addisonian crisis
0.726 0.274 0.000
E07.8 Other specified disorders of thyroid
0.719 0.281 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.717 0.283 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.716 0.284 0.000
E14.2 Withrenal complications
0.715 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.711 0.288 0.000
E14.7 With multiple complications
0.711 0.289 0.000
E14.0 With coma
0.711 0.289 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.289 0.711
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.289 0.711
E16.9 Disorder of pancreatic internal secretion, unspecified
0.708 0.291 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.708 0.291 0.000
E16.4 Abnormal secretion of gastrin
0.708 0.291 0.000
E16.3 Increased secretion of glucagon
0.708 0.291 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.708 0.292 0.000
E14.5 With peripheral circulatory complications
0.706 0.294 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.703 0.296 0.000
E00 Congenital iodine-deficiency syndrome
0.703 0.296 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.700 0.300 0.000
K90.9 Intestinal malabsorption, unspecified
0.699 0.301 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.697 0.303 0.000
E32 Diseases of thymus
0.697 0.303 0.000
E30 Disorders of puberty, not elsewhere classified
0.697 0.303 0.000
E20.9 Hypoparathyroidism, unspecified
0.692 0.308 0.000
E27.5 Adrenomedullary hyperfunction
0.687 0.313 0.000
E27.0 Other adrenocortical overactivity
0.687 0.313 0.000
E14.6 With other specified complications
0.678 0.321 0.000
N45 Orchitis and epididymitis
0.000 0.322 0.678
N41.3 Prostatocystitis
0.000 0.322 0.678
N41.2 Abscess of prostate
0.000 0.322 0.678
N48 Other disorders of penis
0.000 0.322 0.678
E05.5 Thyroid crisis or storm
0.676 0.324 0.000
E05.4 Thyrotoxicosis factitia
0.676 0.324 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.676 0.324 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.676 0.324 0.000
E06 Thyroiditis
0.675 0.325 0.000
N48.4 Impotence of organic origin
0.000 0.327 0.673
E03.5 Myxoedema coma
0.669 0.331 0.000
E03.4 Atrophy of thyroid (acquired)
0.669 0.331 0.000
E03.3 Postinfectious hypothyroidism
0.669 0.331 0.000
E03.1 Congenital hypothyroidism without goitre
0.669 0.331 0.000
E14.8 With unspecified complications
0.664 0.336 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.336 0.664
E24.2 Drug-induced Cushing's syndrome
0.662 0.338 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.338 0.661
E23.0 Hypopituitarism
0.656 0.344 0.000
N42.0 Calculus of prostate
0.000 0.344 0.656
E53 Deficiency of other B group vitamins
0.652 0.348 0.000
E29 Testicular dysfunction
0.651 0.349 0.000
E40-E46 Malnutrition
0.647 0.353 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.646 0.354 0.000
E16.1 Other hypoglycaemia
0.646 0.354 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.640 0.360 0.000
E10.8 With unspecified complications
0.636 0.364 0.000
E07.1 Dyshormogenetic goitre
0.627 0.373 0.000
E07.0 Hypersecretion of calcitonin
0.627 0.373 0.000
E24.0 Pituitary-dependent Cushing's disease
0.624 0.376 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.383 0.617
E24.8 Other Cushing's syndrome
0.613 0.387 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.612 0.388 0.000
E23.1 Drug-induced hypopituitarism
0.612 0.388 0.000
E23.7 Disorder of pituitary gland, unspecified
0.608 0.392 0.000
K90.8 Other intestinal malabsorption
0.608 0.392 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.394 0.605
E31.0 Autoimmune polyglandular failure
0.602 0.398 0.000
E28 Ovarian dysfunction
0.599 0.401 0.000
E61 Deficiency of other nutrient elements
0.597 0.403 0.000
E23.6 Other disorders of pituitary gland
0.594 0.406 0.000
E05.8 Other thyrotoxicosis
0.593 0.407 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.408 0.592
E02 Subclinical iodine-deficiency hypothyroidism
0.582 0.417 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.581 0.418 0.000
E24.3 Ectopic ACTH syndrome
0.581 0.418 0.000
E24.1 Nelson's syndrome
0.581 0.418 0.000
K90.3 Pancreatic steatorrhoea
0.581 0.419 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.581 0.419 0.000
K90.1 Tropical sprue
0.581 0.419 0.000
E20.8 Other hypoparathyroidism
0.580 0.420 0.000
E20.1 Pseudohypoparathyroidism
0.580 0.420 0.000
E20.0 Idiopathic hypoparathyroidism
0.580 0.420 0.000
E26 Hyperaldosteronism
0.580 0.420 0.000
N42.3 Dysplasia of prostate
0.000 0.422 0.578
N41.8 Other inflammatory diseases of prostate
0.000 0.428 0.571
E24.9 Cushing's syndrome, unspecified
0.557 0.443 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.556 0.444 0.000
E53.8 Deficiency of other specified B group vitamins
0.555 0.445 0.000
E51 Thiamine deficiency
0.550 0.450 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.549 0.451 0.000
E63 Other nutritional deficiencies
0.549 0.451 0.000
E56 Other vitamin deficiencies
0.549 0.451 0.000
E50 Vitamin A deficiency
0.549 0.451 0.000
E60 Dietary zinc deficiency
0.549 0.451 0.000
E59 Dietary selenium deficiency
0.549 0.451 0.000
E54 Ascorbic acid deficiency
0.549 0.451 0.000
E52 Niacin deficiency [pellagra]
0.549 0.451 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.454 0.545
E31.9 Polyglandular dysfunction, unspecified
0.542 0.458 0.000
E31.8 Other polyglandular dysfunction
0.542 0.458 0.000
E31.1 Polyglandular hyperfunction
0.542 0.458 0.000
E58 Dietary calcium deficiency
0.541 0.459 0.000
E03.8 Other specified hypothyroidism
0.533 0.467 0.000
E13 Other specified diabetes mellitus
0.533 0.467 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.473 0.527
N42.2 Atrophy of prostate
0.000 0.473 0.527
E25.9 Adrenogenital disorder, unspecified
0.523 0.477 0.000
E25.8 Other adrenogenital disorders
0.523 0.477 0.000
E06.5 Other chronic thyroiditis
0.519 0.481 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E34 Other endocrine disorders
0.513 0.486 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.506 0.494 0.000
N48.1 Balanoposthitis
0.000 0.495 0.505
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.504 0.495 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.504 0.495 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.504 0.495 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.504 0.495 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.504 0.495 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.504 0.495 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.504 0.495 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.504 0.495 0.000
E30.9 Disorder of puberty, unspecified
0.500 0.500 0.000
E30.8 Other disorders of puberty
0.500 0.500 0.000
E30.1 Precocious puberty
0.500 0.500 0.000
E30.0 Delayed puberty
0.500 0.500 0.000
E32.9 Disease of thymus, unspecified
0.500 0.500 0.000
E32.8 Other diseases of thymus
0.500 0.500 0.000
E32.1 Abscess of thymus
0.500 0.500 0.000
E32.0 Persistent hyperplasia of thymus
0.500 0.500 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.500 0.500 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.500 0.500 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.500 0.500 0.000
E53.9 Vitamin B deficiency, unspecified
0.498 0.502 0.000
E61.1 Iron deficiency
0.486 0.514 0.000
E06.4 Drug-induced thyroiditis
0.484 0.516 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.484 0.516 0.000
E06.1 Subacute thyroiditis
0.484 0.516 0.000
E06.0 Acute thyroiditis
0.484 0.516 0.000
E53.1 Pyridoxine deficiency
0.468 0.532 0.000
E53.0 Riboflavin deficiency
0.468 0.532 0.000
E29.9 Testicular dysfunction, unspecified
0.467 0.533 0.000
E29.8 Other testicular dysfunction
0.467 0.533 0.000
E29.0 Testicular hyperfunction
0.467 0.533 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.464 0.536 0.000
E45 Retarded development following protein-energy malnutrition
0.464 0.536 0.000
E43 Unspecified severe protein-energy malnutrition
0.464 0.536 0.000
E42 Marasmic kwashiorkor
0.464 0.536 0.000
E41 Nutritional marasmus
0.464 0.536 0.000
E40 Kwashiorkor
0.464 0.536 0.000
E06.3 Autoimmune thyroiditis
0.449 0.551 0.000
E06.9 Thyroiditis, unspecified
0.447 0.552 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.564 0.436
E11 Non-insulin-dependent diabetes mellitus
0.435 0.565 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.566 0.434
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.566 0.434
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.566 0.434
E28.3 Primary ovarian failure
0.432 0.567 0.000
E22 Hyperfunction of pituitary gland
0.431 0.569 0.000
N48.5 Ulcer of penis
0.000 0.569 0.431
E28.9 Ovarian dysfunction, unspecified
0.430 0.570 0.000
E28.8 Other ovarian dysfunction
0.430 0.570 0.000
E28.1 Androgen excess
0.430 0.570 0.000
E28.0 Oestrogen excess
0.430 0.570 0.000
E61.9 Deficiency of nutrient element, unspecified
0.428 0.572 0.000
E61.8 Deficiency of other specified nutrient elements
0.428 0.572 0.000
E61.7 Deficiency of multiple nutrient elements
0.428 0.572 0.000
E61.6 Vanadium deficiency
0.428 0.572 0.000
E61.5 Molybdenum deficiency
0.428 0.572 0.000
E61.4 Chromium deficiency
0.428 0.572 0.000
E61.3 Manganese deficiency
0.428 0.572 0.000
E61.0 Copper deficiency
0.428 0.572 0.000
E11.5 With peripheral circulatory complications
0.423 0.577 0.000
E29.1 Testicular hypofunction
0.420 0.580 0.000
E26.9 Hyperaldosteronism, unspecified
0.416 0.584 0.000
E26.8 Other hyperaldosteronism
0.416 0.584 0.000
E26.1 Secondary hyperaldosteronism
0.416 0.584 0.000
E61.2 Magnesium deficiency
0.413 0.587 0.000
E21.4 Other specified disorders of parathyroid gland
0.401 0.599 0.000
E51.2 Wernicke's encephalopathy
0.395 0.604 0.000
E46 Unspecified protein-energy malnutrition
0.395 0.605 0.000
E51.9 Thiamine deficiency, unspecified
0.394 0.605 0.000
E51.8 Other manifestations of thiamine deficiency
0.394 0.605 0.000
E51.1 Beriberi
0.394 0.605 0.000
E50.9 Vitamin A deficiency, unspecified
0.393 0.606 0.000
E50.8 Other manifestations of vitamin A deficiency
0.393 0.606 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.393 0.606 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.393 0.606 0.000
E50.5 Vitamin A deficiency with night blindness
0.393 0.606 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.393 0.606 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.393 0.606 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.393 0.606 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.393 0.606 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.393 0.606 0.000
E56.9 Vitamin deficiency, unspecified
0.393 0.606 0.000
E56.8 Deficiency of other vitamins
0.393 0.606 0.000
E56.1 Deficiency of vitamin K
0.393 0.606 0.000
E56.0 Deficiency of vitamin E
0.393 0.606 0.000
E63.9 Nutritional deficiency, unspecified
0.393 0.606 0.000
E63.8 Other specified nutritional deficiencies
0.393 0.606 0.000
E63.1 Imbalance of constituents of food intake
0.393 0.606 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.393 0.606 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.393 0.606 0.000
E64.8 Sequelae of other nutritional deficiencies
0.393 0.606 0.000
E64.3 Sequelae of rickets
0.393 0.606 0.000
E64.2 Sequelae of vitamin C deficiency
0.393 0.606 0.000
E64.1 Sequelae of vitamin A deficiency
0.393 0.606 0.000
E64.0 Sequelae of protein-energy malnutrition
0.393 0.606 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.392 0.608 0.001
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.609 0.391
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.609 0.391
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.609 0.391
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.612 0.388
E13.8 With unspecified complications
0.382 0.618 0.000
E13.7 With multiple complications
0.382 0.618 0.000
E13.6 With other specified complications
0.382 0.618 0.000
E13.5 With peripheral circulatory complications
0.382 0.618 0.000
E13.4 With neurological complications
0.382 0.618 0.000
E13.2 With renal complications
0.382 0.618 0.000
E13.1 With ketoacidosis
0.382 0.618 0.000
E13.0 With coma
0.382 0.618 0.000
N48.3 Priapism
0.000 0.623 0.376
E13.3 With ophthalmic complications
0.376 0.623 0.000
E21.2 Other hyperparathyroidism
0.371 0.629 0.000
E34.5 Androgen resistance syndrome
0.368 0.632 0.000
E34.4 Constitutional tall stature
0.368 0.632 0.000
E34.3 Short stature, not elsewhere classified
0.368 0.632 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.368 0.632 0.000
E34.1 Other hypersecretion of intestinal hormones
0.368 0.632 0.000
E55 Vitamin D deficiency
0.367 0.633 0.000
E34.8 Other specified endocrine disorders
0.367 0.633 0.000
N51.2 Balanitis in diseases classified elsewhere
0.000 0.636 0.364
E11.3 With ophthalmic complications
0.358 0.642 0.000
N50 Other disorders of male genital organs
0.000 0.646 0.354
K40-K46 Hernia
0.000 0.654 0.346
N43 Hydrocele and spermatocele
0.000 0.656 0.344
N48.0 Leukoplakia of penis
0.000 0.665 0.335
E44.1 Mild protein-energy malnutrition
0.333 0.667 0.000
E44.0 Moderate protein-energy malnutrition
0.333 0.667 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.332 0.668 0.000
E21.3 Hyperparathyroidism, unspecified
0.330 0.670 0.000
E28.2 Polycystic ovarian syndrome
0.328 0.672 0.000
K41 Femoral hernia
0.000 0.672 0.328
E34.0 Carcinoid syndrome
0.316 0.683 0.000
E11.6 With other specified complications
0.316 0.684 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.314 0.686 0.000
E11.7 With multiple complications
0.312 0.688 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.309 0.691 0.000
E22.8 Other hyperfunction of pituitary gland
0.309 0.691 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.697 0.303
E26.0 Primary hyperaldosteronism
0.298 0.701 0.000
E11.0 With coma
0.299 0.701 0.000
E11.1 With ketoacidosis
0.292 0.708 0.000
N50.9 Disorder of male genital organs, unspecified
0.000 0.709 0.291
E22.1 Hyperprolactinaemia
0.290 0.710 0.000
N50.0 Atrophy of testis
0.000 0.712 0.288
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.715 0.285
E27.8 Other specified disorders of adrenal gland
0.283 0.716 0.002
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.717 0.283
E34.9 Endocrine disorder, unspecified
0.273 0.727 0.000
E65-E68 Obesity and other hyperalimentation
0.268 0.732 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.733 0.266
E21.0 Primary hyperparathyroidism
0.266 0.734 0.000
E55.0 Rickets, active
0.263 0.736 0.000
K43 Ventral hernia
0.000 0.737 0.263
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.259 0.741 0.000
N43.2 Other hydrocele
0.000 0.753 0.246
N43.1 Infected hydrocele
0.000 0.753 0.246
N43.0 Encysted hydrocele
0.000 0.753 0.246
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.759 0.241
E11.8 With unspecified complications
0.239 0.761 0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.765 0.235
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.765 0.235
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.765 0.235
K46 Unspecified abdominal hernia
0.000 0.765 0.235
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.780 0.220
N42.9 Disorder of prostate, unspecified
0.000 0.780 0.220
N48.9 Disorder of penis, unspecified
0.001 0.789 0.210
E13.9 Without complications
0.210 0.790 0.001
R30.0 Dysuria
0.000 0.807 0.193
E22.0 Acromegaly and pituitary gigantism
0.193 0.807 0.000
E67 Other hyperalimentation
0.192 0.808 0.000
E68 Sequelae of hyperalimentation
0.192 0.808 0.000
R30 Pain associated with micturition
0.000 0.809 0.191
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.811 0.189
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.811 0.189
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.811 0.189
K43.4 Parastomal hernia with gangrene
0.000 0.811 0.189
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.811 0.189
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.811 0.189
K43.1 Ventral hernia with gangrene
0.000 0.811 0.189
R30-R39 Symptoms and signs involving the urinary system
0.000 0.812 0.188
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.825 0.175
K44 Diaphragmatic hernia
0.000 0.826 0.174
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.831 0.168
N43.4 Spermatocele
0.001 0.844 0.155
K45 Other abdominal hernia
0.000 0.846 0.154
R30.1 Vesical tenesmus
0.000 0.848 0.152
N48.6 Balanitis xerotica obliterans
0.000 0.853 0.147
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.854 0.146
R30.9 Painful micturition, unspecified
0.000 0.859 0.141
E67.8 Other specified hyperalimentation
0.138 0.862 0.000
E67.3 Hypervitaminosis D
0.138 0.862 0.000
E67.2 Megavitamin-B6 syndrome
0.138 0.862 0.000
E67.1 Hypercarotenaemia
0.138 0.862 0.000
E67.0 Hypervitaminosis A
0.138 0.862 0.000
K42 Umbilical hernia
0.000 0.864 0.136
K44.1 Diaphragmatic hernia with gangrene
0.000 0.864 0.136
E11.2 With renal complications
0.131 0.868 0.000
R36 Urethral discharge
0.000 0.872 0.128
E04 Other non-toxic goitre
0.127 0.873 0.000
N48.8 Other specified disorders of penis
0.000 0.874 0.126
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.877 0.123
N43.3 Hydrocele, unspecified
0.000 0.878 0.122
E83 Disorders of mineral metabolism
0.015 0.880 0.105
K45.1 Other specified abdominal hernia with gangrene
0.000 0.889 0.110
R34 Anuria and oliguria
0.000 0.894 0.106
R47.0 Dysphasia and aphasia
0.103 0.897 0.000
E65 Localised adiposity
0.101 0.898 0.001
K42.1 Umbilical hernia with gangrene
0.000 0.902 0.098
I83 Varicose veins of lower extremities
0.000 0.905 0.095
E04.8 Other specified non-toxic goitre
0.091 0.908 0.000
E83.3 Disorders of phosphorus metabolism
0.005 0.911 0.083
E83.9 Disorder of mineral metabolism, unspecified
0.011 0.914 0.075
E83.8 Other disorders of mineral metabolism
0.011 0.914 0.075
E83.2 Disorders of zinc metabolism
0.011 0.914 0.075
E83.0 Disorders of copper metabolism
0.011 0.914 0.075
R35 Polyuria
0.000 0.914 0.086
E55.9 Vitamin D deficiency, unspecified
0.082 0.918 0.000
E04.0 Non-toxic diffuse goitre
0.081 0.919 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.923 0.077
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.924 0.076
E11.4 With neurological complications
0.074 0.925 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.928 0.071
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.935 0.065
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.942 0.058
N50.1 Vascular disorders of male genital organs
0.000 0.943 0.057
E04.1 Non-toxic single thyroid nodule
0.056 0.944 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.945 0.055
R47 Speech disturbances, not elsewhere classified
0.053 0.947 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.948 0.052
E70-E90 Metabolic disorders
0.049 0.948 0.003
K90-K93 Other diseases of the digestive system
0.049 0.950 0.001
R39 Other symptoms and signs involving the urinary system
0.000 0.950 0.050
R47.1 Dysarthria and anarthria
0.045 0.955 0.000
E73 Lactose intolerance
0.043 0.955 0.002
E84 Cystic fibrosis
0.039 0.959 0.002
E73.9 Lactose intolerance, unspecified
0.039 0.960 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.037 0.961 0.002
E88 Other metabolic disorders
0.038 0.961 0.001
E79 Disorders of purine and pyrimidine metabolism
0.035 0.963 0.002
E77 Disorders of glycoprotein metabolism
0.035 0.963 0.002
E76 Disorders of glycosaminoglycan metabolism
0.035 0.963 0.002
E72 Other disorders of amino-acid metabolism
0.035 0.963 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.035 0.963 0.002
E70 Disorders of aromatic amino-acid metabolism
0.035 0.963 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.035 0.963 0.002
E04.9 Non-toxic goitre, unspecified
0.036 0.964 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.035 0.964 0.001
R39.2 Extrarenal uraemia
0.000 0.964 0.036
E84.9 Cystic fibrosis, unspecified
0.033 0.966 0.001
E74 Other disorders of carbohydrate metabolism
0.031 0.967 0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.033 0.967 0.000
E83.4 Disorders of magnesium metabolism
0.011 0.968 0.021
E73.8 Other lactose intolerance
0.031 0.968 0.001
E73.1 Secondary lactase deficiency
0.031 0.968 0.001
E73.0 Congenital lactase deficiency
0.031 0.968 0.001
E04.2 Non-toxic multinodular goitre
0.032 0.968 0.000
E88.2 Lipomatosis, not elsewhere classified
0.031 0.968 0.001
E88.9 Metabolic disorder, unspecified
0.031 0.969 0.001
E78.1 Pure hyperglyceridaemia
0.031 0.969 0.000
E84.8 Cystic fibrosis with other manifestations
0.028 0.970 0.002
E84.1 Cystic fibrosis with intestinal manifestations
0.028 0.970 0.002
E84.0 Cystic fibrosis with pulmonary manifestations
0.028 0.970 0.002
E75.2 Other sphingolipidosis
0.028 0.970 0.001
E78.6 Lipoprotein deficiency
0.030 0.970 0.000
E85 Amyloidosis
0.027 0.971 0.002
R47.8 Other and unspecified speech disturbances
0.029 0.971 0.000
E66 Obesity
0.029 0.971 0.000
E75.5 Other lipid storage disorders
0.027 0.971 0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.028 0.971 0.000
K75.4 Autoimmune hepatitis
0.029 0.971 0.000
E11.9 Without complications
0.028 0.972 0.000
E75.6 Lipid storage disorder, unspecified
0.027 0.972 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.027 0.972 0.002
E75.3 Sphingolipidosis, unspecified
0.027 0.972 0.002
E75.1 Other gangliosidosis
0.027 0.972 0.002
E75.0 GM2 gangliosidosis
0.027 0.972 0.002
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.972 0.028
R39.0 Extravasation of urine
0.000 0.973 0.027
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.025 0.973 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.025 0.973 0.002
E70.3 Albinism
0.025 0.973 0.002
E70.2 Disorders of tyrosine metabolism
0.025 0.973 0.002
E70.1 Other hyperphenylalaninaemias
0.025 0.973 0.002
E70.0 Classical phenylketonuria
0.025 0.973 0.002
E71.3 Disorders of fatty-acid metabolism
0.025 0.973 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.025 0.973 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.025 0.973 0.002
E71.0 Maple-syrup-urine disease
0.025 0.973 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.025 0.973 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.025 0.973 0.002
E72.5 Disorders of glycine metabolism
0.025 0.973 0.002
E72.4 Disorders of ornithine metabolism
0.025 0.973 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.025 0.973 0.002
E72.2 Disorders of urea cycle metabolism
0.025 0.973 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.025 0.973 0.002
E72.0 Disorders of amino-acid transport
0.025 0.973 0.002
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.025 0.973 0.002
E76.8 Other disorders of glucosaminoglycan metabolism
0.025 0.973 0.002
E76.3 Mucopolysaccharidosis, unspecified
0.025 0.973 0.002
E76.2 Other mucopolysaccharidoses
0.025 0.973 0.002
E76.1 Mucopolysaccharidosis, type II
0.025 0.973 0.002
E76.0 Mucopolysaccharidosis, type I
0.025 0.973 0.002
E77.9 Disorder of glycoprotein metabolism, unspecified
0.025 0.973 0.002
E77.8 Other disorders of glycoprotein metabolism
0.025 0.973 0.002
E77.1 Defects in glycoprotein degradation
0.025 0.973 0.002
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.025 0.973 0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.025 0.973 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.025 0.973 0.002
E79.1 Lesch-Nyhan syndrome
0.025 0.973 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.025 0.973 0.002
E88.8 Other specified metabolic disorders
0.025 0.974 0.001
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.025 0.974 0.001
K93.1 Megacolon in Chagas' disease
0.025 0.974 0.001
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.025 0.974 0.001
E88.3 Tumour lysis syndrome
0.025 0.974 0.001
E88.1 Lipodystrophy, not elsewhere classified
0.024 0.975 0.001
E78.2 Mixed hyperlipidaemia
0.025 0.975 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.975 0.025
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.975 0.025
E74.9 Disorder of carbohydrate metabolism, unspecified
0.022 0.976 0.002
E74.8 Other specified disorders of carbohydrate metabolism
0.022 0.976 0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.022 0.976 0.002
E74.2 Disorders of galactose metabolism
0.022 0.976 0.002
E74.1 Disorders of fructose metabolism
0.022 0.976 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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