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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2043305
log Bayes Factor = 7.94393
Chromosome 19   position 10,728,320  (GRCh37) Explore rs2043305 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.000 1.000
Z86.7 Personal history of diseases of the circulatory system
0.000 0.037 0.963
I25.1 Atherosclerotic heart disease
0.000 0.074 0.926
I26 Pulmonary embolism
0.000 0.120 0.880
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.137 0.863
I80 Phlebitis and thrombophlebitis
0.000 0.145 0.855
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.207 0.793
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.210 0.790
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.216 0.784
I25 Chronic ischaemic heart disease
0.000 0.220 0.780
I20-I25 Ischaemic heart diseases
0.000 0.221 0.779
Chapter IX Diseases of the circulatory system
0.000 0.240 0.760
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.245 0.755
I24 Other acute ischaemic heart diseases
0.000 0.261 0.739
I21 Acute myocardial infarction
0.000 0.291 0.709
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.295 0.705
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.306 0.694
I82 Other venous embolism and thrombosis
0.000 0.315 0.685
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.342 0.658
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.345 0.655
T36-T50 Poisoning by drugs, medicaments and biological substances
0.649 0.351 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.353 0.647
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.643 0.357 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.359 0.641
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.636 0.364 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.626 0.374 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.622 0.378 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.386 0.614
I23 Certain current complications following acute myocardial infarction
0.000 0.389 0.611
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.405 0.595
I24.1 Dressler's syndrome
0.000 0.406 0.594
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.409 0.591
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.585 0.415 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.421 0.579
T43.5 Other and unspecified antipsychotics and neuroleptics
0.579 0.421 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.578 0.422 0.000
I82.8 Embolism and thrombosis of other specified veins
0.000 0.427 0.573
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.568 0.432 0.000
I89.1 Lymphangitis
0.000 0.439 0.561
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.560 0.440 0.000
I25.6 Silent myocardial ischaemia
0.000 0.441 0.559
I25.2 Old myocardial infarction
0.000 0.444 0.556
I25.5 Ischaemic cardiomyopathy
0.000 0.446 0.554
I28 Other diseases of pulmonary vessels
0.000 0.454 0.546
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.545 0.455 0.000
I00-I02 Acute rheumatic fever
0.000 0.460 0.540
I82.2 Embolism and thrombosis of vena cava
0.000 0.464 0.536
T50.8 Diagnostic agents
0.530 0.469 0.000
T43.2 Other and unspecified antidepressants
0.525 0.475 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.524 0.476 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.519 0.481 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.519 0.481 0.000
T45.0 Antiallergic and antiemetic drugs
0.518 0.482 0.000
I82.3 Embolism and thrombosis of renal vein
0.000 0.490 0.510
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.490 0.510
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.492 0.508
I22 Subsequent myocardial infarction
0.000 0.497 0.503
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.501 0.499 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.504 0.496
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.496 0.504 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.495 0.505 0.000
I82.1 Thrombophlebitis migrans
0.000 0.509 0.491
I23.8 Other current complications following acute myocardial infarction
0.000 0.509 0.491
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.490 0.510 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.485 0.515 0.000
T40.2 Other opioids
0.466 0.534 0.000
I89.0 Lymphoedema, not elsewhere classified
0.000 0.534 0.466
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.465 0.534 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.465 0.534 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.461 0.539 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.461 0.539 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.461 0.539 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.461 0.539 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.461 0.539 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.461 0.539 0.000
T44.0 Anticholinesterase agents
0.461 0.539 0.000
T50.7 Analeptics and opioid receptor antagonists
0.456 0.544 0.000
T50.5 Appetite depressants
0.456 0.544 0.000
T50.4 Drugs affecting uric acid metabolism
0.456 0.544 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.456 0.544 0.000
T50.1 Loop [high-ceiling] diuretics
0.456 0.544 0.000
T50.0 Mineralocorticoids and their antagonists
0.456 0.544 0.000
T36 Poisoning by systemic antibiotics
0.456 0.544 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.455 0.545 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.452 0.548 0.000
T43.9 Psychotropic drug, unspecified
0.446 0.554 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.446 0.554 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.446 0.554 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.440 0.560 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.562 0.438
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.562 0.438
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.562 0.438
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.562 0.438
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.562 0.438
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.562 0.438
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.562 0.438
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.438 0.562 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.564 0.436
I82.0 Budd-Chiari syndrome
0.000 0.573 0.427
I88 Nonspecific lymphadenitis
0.000 0.573 0.426
T45.2 Vitamins, not elsewhere classified
0.417 0.583 0.000
I60-I69 Cerebrovascular diseases
0.000 0.584 0.416
T43.6 Psychostimulants with abuse potential
0.414 0.586 0.000
T42.3 Barbiturates
0.411 0.589 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.409 0.591 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.407 0.593 0.000
T45.8 Other primarily systemic and haematological agents
0.407 0.593 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.407 0.593 0.000
T45.6 Fibrinolysis-affecting drugs
0.407 0.593 0.000
T45.4 Iron and its compounds
0.407 0.593 0.000
T45.3 Enzymes, not elsewhere classified
0.407 0.593 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.399 0.601 0.000
T40.6 Other and unspecified narcotics
0.399 0.601 0.000
T45.5 Anticoagulants
0.399 0.601 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.394 0.606 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.608 0.392
I28.1 Aneurysm of pulmonary artery
0.000 0.608 0.392
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.608 0.392
I86 Varicose veins of other sites
0.000 0.609 0.391
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.391 0.609 0.000
T40.8 Lysergide [LSD]
0.391 0.609 0.000
T40.7 Cannabis (derivatives)
0.391 0.609 0.000
T40.5 Cocaine
0.391 0.609 0.000
T40.3 Methadone
0.391 0.609 0.000
T40.1 Heroin
0.391 0.609 0.000
T40.0 Opium
0.391 0.609 0.000
T40.4 Other synthetic narcotics
0.390 0.610 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.612 0.388
I02 Rheumatic chorea
0.000 0.613 0.387
I01 Rheumatic fever with heart involvement
0.000 0.613 0.387
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.386 0.614 0.000
T42.1 Iminostilbenes
0.384 0.616 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.616 0.384
I00 Rheumatic fever without mention of heart involvement
0.000 0.618 0.382
T42.4 Benzodiazepines
0.381 0.619 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.619 0.381
T45.1 Antineoplastic and immunosuppressive drugs
0.376 0.624 0.000
I28.8 Other specified diseases of pulmonary vessels
0.000 0.624 0.376
T48.5 Anti-common-cold drugs
0.376 0.624 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.627 0.373
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.372 0.628 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.372 0.628 0.000
T42.2 Succinimides and oxazolidinediones
0.372 0.628 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.366 0.634 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.635 0.364
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.636 0.364
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.359 0.641 0.000
T37.5 Antiviral drugs
0.359 0.641 0.000
T37.4 Anthelminthics
0.359 0.641 0.000
T37.3 Other antiprotozoal drugs
0.359 0.641 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.359 0.641 0.000
T37.1 Antimycobacterial drugs
0.359 0.641 0.000
T37.0 Sulphonamides
0.359 0.641 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.357 0.643 0.000
T38.9 Other and unspecified hormone antagonists
0.355 0.644 0.000
T38.7 Androgens and anabolic congeners
0.355 0.644 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.355 0.644 0.000
T38.5 Other oestrogens and progestogens
0.355 0.644 0.000
T38.4 Oral contraceptives
0.355 0.644 0.000
T38.2 Antithyroid drugs
0.355 0.644 0.000
T38.0 Glucocorticoids and synthetic analogues
0.355 0.644 0.000
T39.4 Antirheumatics, not elsewhere classified
0.355 0.645 0.000
T39.2 Pyrazolone derivatives
0.355 0.645 0.000
I87 Other disorders of veins
0.001 0.646 0.353
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.351 0.649 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.351 0.649 0.000
T48.4 Expectorants
0.351 0.649 0.000
T48.3 Antitussives
0.351 0.649 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.351 0.649 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.351 0.649 0.000
T48.0 Oxytocic drugs
0.351 0.649 0.000
I60 Subarachnoid haemorrhage
0.000 0.651 0.349
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.657 0.342
T43.0 Tricyclic and tetracyclic antidepressants
0.339 0.661 0.000
T47.0 Histamine H(2)-receptor antagonists
0.338 0.662 0.000
T41.5 Therapeutic gases
0.334 0.666 0.000
T41.4 Anaesthetic, unspecified
0.334 0.666 0.000
T41.3 Local anaesthetics
0.334 0.666 0.000
T41.2 Other and unspecified general anaesthetics
0.334 0.666 0.000
T41.1 Intravenous anaesthetics
0.334 0.666 0.000
T41.0 Inhaled anaesthetics
0.334 0.666 0.000
T49.9 Topical agent, unspecified
0.334 0.666 0.000
T49.8 Other topical agents
0.334 0.666 0.000
T49.7 Dental drugs, topically applied
0.334 0.666 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.334 0.666 0.000
T49.5 Ophthalmological drugs and preparations
0.334 0.666 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.334 0.666 0.000
T49.3 Emollients, demulcents and protectants
0.334 0.666 0.000
T49.2 Local astringents and local detergents
0.334 0.666 0.000
T49.1 Antipruritics
0.334 0.666 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.334 0.666 0.000
T39.0 Salicylates
0.332 0.668 0.000
T36.9 Systemic antibiotic, unspecified
0.327 0.673 0.000
T36.8 Other systemic antibiotics
0.327 0.673 0.000
T36.7 Antifungal antibiotics, systemically used
0.327 0.673 0.000
T36.6 Rifamycins
0.327 0.673 0.000
T36.5 Aminoglycosides
0.327 0.673 0.000
T36.4 Tetracyclines
0.327 0.673 0.000
T36.3 Macrolides
0.327 0.673 0.000
T36.2 Chloramphenicol group
0.327 0.673 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.327 0.673 0.000
I25.3 Aneurysm of heart
0.000 0.676 0.324
I86.8 Varicose veins of other specified sites
0.000 0.679 0.320
I63 Cerebral infarction
0.000 0.681 0.319
T36.0 Penicillins
0.317 0.682 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.315 0.684 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.315 0.684 0.000
T47.7 Emetics
0.315 0.684 0.000
T47.6 Antidiarrhoeal drugs
0.315 0.684 0.000
T47.5 Digestants
0.315 0.684 0.000
T47.4 Other laxatives
0.315 0.684 0.000
T47.3 Saline and osmotic laxatives
0.315 0.684 0.000
T47.2 Stimulant laxatives
0.315 0.684 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.685 0.315
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.689 0.311
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.310 0.689 0.000
I67 Other cerebrovascular diseases
0.000 0.693 0.307
I88.8 Other nonspecific lymphadenitis
0.000 0.694 0.306
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.694 0.306
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.694 0.306
I87.8 Other specified disorders of veins
0.000 0.697 0.303
I83 Varicose veins of lower extremities
0.000 0.701 0.299
I85 Oesophageal varices
0.000 0.704 0.295
I25.4 Coronary artery aneurysm
0.001 0.705 0.294
T38.1 Thyroid hormones and substitutes
0.291 0.709 0.000
T42.0 Hydantoin derivatives
0.284 0.716 0.000
I86.3 Vulval varices
0.000 0.719 0.281
I86.0 Sublingual varices
0.000 0.719 0.281
I20 Angina pectoris
0.000 0.719 0.281
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.720 0.280
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.722 0.278
I01.8 Other acute rheumatic heart disease
0.000 0.722 0.278
I01.2 Acute rheumatic myocarditis
0.000 0.722 0.278
I01.1 Acute rheumatic endocarditis
0.000 0.722 0.278
I01.0 Acute rheumatic pericarditis
0.000 0.722 0.278
I02.9 Rheumatic chorea without heart involvement
0.000 0.722 0.278
I02.0 Rheumatic chorea with heart involvement
0.000 0.722 0.278
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.726 0.274
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.728 0.272
I60.8 Other subarachnoid haemorrhage
0.000 0.731 0.269
I67.8 Other specified cerebrovascular diseases
0.000 0.732 0.268
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.735 0.265
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.263 0.737 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.262 0.737 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.262 0.737 0.000
T46.7 Peripheral vasodilators
0.262 0.737 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.262 0.737 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.262 0.737 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.262 0.737 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.737 0.263
T46.1 Calcium-channel blockers
0.261 0.738 0.000
I86.2 Pelvic varices
0.000 0.740 0.260
T46.5 Other antihypertensive drugs, not elsewhere classified
0.259 0.741 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.743 0.257
T47.1 Other antacids and anti-gastric-secretion drugs
0.256 0.743 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.746 0.254
I87.9 Disorder of vein, unspecified
0.001 0.746 0.253
I87.0 Postphlebitic syndrome
0.001 0.746 0.253
I63.8 Other cerebral infarction
0.000 0.748 0.252
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.750 0.250
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.750 0.250
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.750 0.250
I20.9 Angina pectoris, unspecified
0.000 0.751 0.249
I67.1 Cerebral aneurysm, nonruptured
0.000 0.753 0.247
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.755 0.245
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.758 0.241
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.766 0.234
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.769 0.231
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.771 0.229
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.771 0.229
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.772 0.228
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.774 0.226
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.774 0.226
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.774 0.226
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.774 0.226
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.774 0.226
I86.4 Gastric varices
0.000 0.779 0.221
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.780 0.220
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.780 0.220
I67.5 Moyamoya disease
0.000 0.780 0.220
I67.4 Hypertensive encephalopathy
0.000 0.780 0.220
I67.3 Progressive vascular leukoencephalopathy
0.000 0.780 0.220
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.783 0.217
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.785 0.215
I67.2 Cerebral atherosclerosis
0.000 0.790 0.210
I62 Other nontraumatic intracranial haemorrhage
0.000 0.790 0.210
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.792 0.208
I81 Portal vein thrombosis
0.001 0.793 0.206
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.793 0.207
I71 Aortic aneurysm and dissection
0.000 0.798 0.202
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.798 0.202
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.799 0.201
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.799 0.201
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.799 0.201
I05-I09 Chronic rheumatic heart diseases
0.000 0.799 0.201
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.802 0.198
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.803 0.197
I27 Other pulmonary heart diseases
0.000 0.805 0.195
I88.9 Nonspecific lymphadenitis, unspecified
0.001 0.809 0.190
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.811 0.188
I65.1 Occlusion and stenosis of basilar artery
0.000 0.811 0.188
I85.0 Oesophageal varices with bleeding
0.000 0.812 0.188
I21.9 Acute myocardial infarction, unspecified
0.000 0.813 0.187
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.814 0.185
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.817 0.183
I68.0 Cerebral amyloid angiopathy
0.000 0.817 0.182
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.819 0.181
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.821 0.178
I63.9 Cerebral infarction, unspecified
0.000 0.822 0.178
I20.1 Angina pectoris with documented spasm
0.000 0.824 0.176
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.826 0.174
T46.4 Angiotensin-converting-enzyme inhibitors
0.170 0.829 0.000
I86.1 Scrotal varices
0.000 0.831 0.169
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.834 0.166
I65.2 Occlusion and stenosis of carotid artery
0.000 0.838 0.162
I70 Atherosclerosis
0.000 0.841 0.159
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.844 0.156
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.845 0.155
I27.8 Other specified pulmonary heart diseases
0.000 0.847 0.153
I87.1 Compression of vein
0.001 0.847 0.152
I62.1 Nontraumatic extradural haemorrhage
0.000 0.849 0.151
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.850 0.150
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.852 0.148
I21.4 Acute subendocardial myocardial infarction
0.000 0.854 0.146
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.854 0.146
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.855 0.145
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.855 0.145
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.855 0.145
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.855 0.145
I10-I15 Hypertensive diseases
0.000 0.855 0.145
I06 Rheumatic aortic valve diseases
0.000 0.856 0.144
I27.1 Kyphoscoliotic heart disease
0.000 0.860 0.140
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.866 0.134
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.867 0.133
I70.0 Atherosclerosis of aorta
0.000 0.870 0.130
I70.1 Atherosclerosis of renal artery
0.000 0.872 0.128
I07 Rheumatic tricuspid valve diseases
0.000 0.876 0.124
I09 Other rheumatic heart diseases
0.000 0.877 0.123
I61 Intracerebral haemorrhage
0.000 0.877 0.123
T39.1 4-Aminophenol derivatives
0.116 0.884 0.000
I74 Arterial embolism and thrombosis
0.000 0.885 0.115
I99 Other and unspecified disorders of circulatory system
0.000 0.885 0.115
I70.9 Generalised and unspecified atherosclerosis
0.000 0.886 0.114
I70.8 Atherosclerosis of other arteries
0.000 0.886 0.114
I27.9 Pulmonary heart disease, unspecified
0.000 0.889 0.111
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.891 0.109
I15 Secondary hypertension
0.000 0.894 0.106
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.894 0.106
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.895 0.105
I79.1 Aortitis in diseases classified elsewhere
0.000 0.895 0.105
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.895 0.105
I13 Hypertensive heart and renal disease
0.000 0.896 0.104
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.896 0.103
I06.8 Other rheumatic aortic valve diseases
0.000 0.896 0.103
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.896 0.103
I06.1 Rheumatic aortic insufficiency
0.000 0.896 0.103
I06.0 Rheumatic aortic stenosis
0.000 0.896 0.103
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.898 0.102
I78 Diseases of capillaries
0.000 0.899 0.101
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.904 0.095
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.907 0.093
I08 Multiple valve diseases
0.000 0.907 0.093
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.908 0.092
I74.5 Embolism and thrombosis of iliac artery
0.000 0.909 0.091
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.911 0.089
I07.9 Tricuspid valve disease, unspecified
0.000 0.911 0.089
I07.8 Other tricuspid valve diseases
0.000 0.911 0.089
I07.2 Tricuspid stenosis with insufficiency
0.000 0.911 0.089
I07.0 Tricuspid stenosis
0.000 0.911 0.089
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.911 0.089
I09.8 Other specified rheumatic heart diseases
0.000 0.912 0.088
I09.2 Chronic rheumatic pericarditis
0.000 0.912 0.088
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.912 0.088
I09.0 Rheumatic myocarditis
0.000 0.912 0.088
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.912 0.088
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.913 0.087
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.913 0.087
I05 Rheumatic mitral valve diseases
0.000 0.913 0.086
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.915 0.085
I15.9 Seconday hypertension, unspecified
0.000 0.916 0.084
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.917 0.083
I74.8 Embolism and thrombosis of other arteries
0.000 0.918 0.082
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.918 0.082
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.918 0.082
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.918 0.082
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.918 0.082
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.918 0.082
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.920 0.080
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.920 0.080
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.921 0.079
I61.8 Other intracerebral haemorrhage
0.000 0.921 0.079
I11 Hypertensive heart disease
0.000 0.923 0.077
I71.0 Dissection of aorta [any part]
0.000 0.923 0.077
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.923 0.077
I15.8 Other secondary hypertension
0.000 0.924 0.076
I15.2 Hypertension secondary to endocrine disorders
0.000 0.924 0.076
I15.0 Renovascular hypertension
0.000 0.924 0.076
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.924 0.076
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.924 0.075
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.925 0.075
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.925 0.075
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.925 0.075
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.925 0.075
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.926 0.074
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.927 0.073
I78.9 Disease of capillaries, unspecified
0.000 0.927 0.073
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.929 0.071
I87.2 Venous insufficiency (chronic) (peripheral)
0.002 0.929 0.069
I07.1 Tricuspid insufficiency
0.000 0.931 0.069
I15.1 Hypertension secondary to other renal disorders
0.000 0.931 0.068
I09.9 Rheumatic heart disease, unspecified
0.000 0.933 0.067
I20.8 Other forms of angina pectoris
0.000 0.933 0.067
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.935 0.065
I12 Hypertensive renal disease
0.000 0.935 0.065
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.935 0.064
I08.9 Multiple valve disease, unspecified
0.000 0.937 0.063
I08.8 Other multiple valve diseases
0.000 0.937 0.063
I05.8 Other mitral valve diseases
0.000 0.938 0.062
I05.9 Mitral valve disease, unspecified
0.000 0.938 0.062
I05.2 Mitral stenosis with insufficiency
0.000 0.941 0.059
I69 Sequelae of cerebrovascular disease
0.000 0.942 0.058
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.943 0.057
I77 Other disorders of arteries and arterioles
0.000 0.943 0.057
I27.0 Primary pulmonary hypertension
0.000 0.943 0.056
I78.8 Other diseases of capillaries
0.000 0.945 0.054
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.946 0.054
I97.0 Postcardiotomy syndrome
0.000 0.946 0.054
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.946 0.054
I27.2 Other secondary pulmonary hypertension
0.000 0.947 0.053
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.947 0.052
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.947 0.052
I98.0 Cardiovascular syphilis
0.000 0.947 0.052
M48.02 Spinal stenosis (Cervical region)
0.051 0.949 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.952 0.047
I05.1 Rheumatic mitral insufficiency
0.000 0.953 0.046
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.953 0.047
I97.1 Other functional disturbances following cardiac surgery
0.000 0.954 0.046
I12.9 Hypertensive renal disease without renal failure
0.000 0.954 0.046
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.954 0.046
I77.2 Rupture of artery
0.000 0.955 0.045
I05.0 Mitral stenosis
0.000 0.957 0.042
I72 Other aneurysm
0.000 0.958 0.042
I77.5 Necrosis of artery
0.000 0.959 0.041
I77.4 Coeliac artery compression syndrome
0.000 0.959 0.041
I77.0 Arteriovenous fistula, acquired
0.000 0.960 0.040
I85.9 Oesophageal varices without bleeding
0.001 0.960 0.039
I77.8 Other specified disorders of arteries and arterioles
0.000 0.960 0.040
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.962 0.038
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.962 0.038
I78.1 Naevus, nonneoplastic
0.000 0.962 0.038
I77.3 Arterial fibromuscular dysplasia
0.000 0.963 0.037
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.965 0.034
M48.07 Spinal stenosis (Lumbosacral region)
0.034 0.966 0.000
I67.9 Cerebrovascular disease, unspecified
0.000 0.966 0.034
I77.6 Arteritis, unspecified
0.000 0.967 0.033
I69.3 Sequelae of cerebral infarction
0.000 0.967 0.033
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.967 0.033
M48.0 Spinal stenosis
0.033 0.967 0.000
I73 Other peripheral vascular diseases
0.000 0.968 0.032
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.970 0.030
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.970 0.030
I08.0 Disorders of both mitral and aortic valves
0.000 0.970 0.030
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.971 0.029
I20.0 Unstable angina
0.000 0.972 0.028
I72.8 Aneurysm of other specified arteries
0.000 0.972 0.027
I72.2 Aneurysm of renal artery
0.000 0.973 0.027
I77.1 Stricture of artery
0.000 0.973 0.027
I72.0 Aneurysm of carotid artery
0.000 0.973 0.026
I72.1 Aneurysm of artery of upper extremity
0.000 0.974 0.026
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.974 0.026
I72.4 Aneurysm of artery of lower extremity
0.000 0.974 0.026
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.974 0.026
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.974 0.026
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.025 0.975 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.975 0.024
M48.05 Spinal stenosis (Thoracolumbar region)
0.024 0.976 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.024 0.976 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
I72.3 Aneurysm of iliac artery
0.000 0.977 0.023
X60-X84 Intentional self-harm
0.023 0.977 0.000
X63.0 Home
0.023 0.977 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.023 0.977 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.978 0.022
I72.9 Aneurysm of unspecified site
0.001 0.979 0.021
M48.09 Spinal stenosis (Site unspecified)
0.021 0.979 0.000
Z91.5 Personal history of self-harm
0.021 0.979 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.020 0.980 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.020 0.980 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.020 0.980 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.020 0.980 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.980 0.020
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.981 0.019
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.981 0.019
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.981 0.019
M48.04 Spinal stenosis (Thoracic region)
0.019 0.981 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.019 0.981 0.000
X78 Intentional self-harm by sharp object
0.019 0.981 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.018 0.982 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.018 0.982 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.018 0.982 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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