TreeWAS – Variant ID: rs20476

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter XII Diseases of the skin and subcutaneous tissue	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004
Chapter XX External causes of morbidity and mortality	0.988	0.012
M45-M49 Spondylopathies	0.971	0.029
S60-S69 Injuries to the wrist and hand	0.964	0.036
Chapter I Certain infectious and parasitic diseases	0.964	0.036
L60-L75 Disorders of skin appendages	0.964	0.036
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.960	0.040
S00-S09 Injuries to the head	0.953	0.047
M20-M25 Other joint disorders	0.937	0.063
L72 Follicular cysts of skin and subcutaneous tissue	0.937	0.063
M47 Spondylosis	0.937	0.063
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.926	0.074
A30-A49 Other bacterial diseases	0.925	0.075
A41 Other septicaemia	0.896	0.104
M47.8 Other spondylosis	0.894	0.106
L72.1 Trichilemmal cyst	0.891	0.109
S64 Injury of nerves at wrist and hand level	0.888	0.112
Chapter II Neoplasms	0.884	0.116
L80-L99 Other disorders of the skin and subcutaneous tissue	0.884	0.116
L20-L30 Dermatitis and eczema	0.882	0.118
M05-M14 Inflammatory polyarthropathies	0.879	0.121
Chapter VII Diseases of the eye and adnexa	0.866	0.134
L40-L45 Papulosquamous disorders	0.860	0.140
A41.9 Septicaemia, unspecified	0.854	0.146
M23 Internal derangement of knee	0.849	0.151
S80-S89 Injuries to the knee and lower leg	0.841	0.159
S06 Intracranial injury	0.841	0.159
S64.4 Injury of digital nerve of other finger	0.834	0.166
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.833	0.167
S01 Open wound of head	0.823	0.177
L72.0 Epidermal cyst	0.820	0.180
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.819	0.181
W00-W19 Falls	0.819	0.181
Y43 Primarily systemic agents	0.815	0.185
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.813	0.187
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.810	0.190
M47.82 Other spondylosis (Cervical region)	0.807	0.193
S40-S49 Injuries to the shoulder and upper arm	0.803	0.197
Y40 Systemic antibiotics	0.803	0.197
Chapter VIII Diseases of the ear and mastoid process	0.797	0.203
S61 Open wound of wrist and hand	0.794	0.206
W20-W49 Exposure to inanimate mechanical forces	0.793	0.207
B35-B49 Mycoses	0.787	0.213
Y57 Other and unspecified drugs and medicaments	0.782	0.218
S00 Superficial injury of head	0.782	0.218
M49 Spondylopathies in diseases classified elsewhere	0.780	0.220
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.779	0.221
B95-B98 Bacterial, viral and other infectious agents	0.778	0.222
M47.80 Other spondylosis (Multiple sites in spine)	0.776	0.224
M23.2 Derangement of meniscus due to old tear or injury	0.774	0.226
S62 Fracture at wrist and hand level	0.772	0.228
S20-S29 Injuries to the thorax	0.770	0.230
C50-C50 Malignant neoplasm of breast	0.768	0.232
L30 Other dermatitis	0.764	0.236
L40 Psoriasis	0.762	0.238
S66 Injury of muscle and tendon at wrist and hand level	0.762	0.238
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.758	0.242
M40-M43 Deforming dorsopathies	0.757	0.243
M10 Gout	0.756	0.244
H43-H45 Disorders of vitreous body and globe	0.756	0.244
M25 Other joint disorders, not elsewhere classified	0.754	0.246
Y51 Drugs primarily affecting the autonomic nervous system	0.750	0.250
L82 Seborrhoeic keratosis	0.748	0.252
M47.2 Other spondylosis with radiculopathy	0.747	0.253
M86-M90 Other osteopathies	0.747	0.253
M50-M54 Other dorsopathies	0.745	0.255
T66-T78 Other and unspecified effects of external causes	0.744	0.256
L84 Corns and callosities	0.741	0.259
S90-S99 Injuries to the ankle and foot	0.732	0.268
M48 Other spondylopathies	0.732	0.268
L60 Nail disorders	0.730	0.270
Chapter XXII Codes for special purposes	0.730	0.270
T15-T19 Effects of foreign body entering through natural orifice	0.730	0.270
T85 Complications of other internal prosthetic devices, implants and grafts	0.730	0.270
T88 Other complications of surgical and medical care, not elsewhere classified	0.728	0.272
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.728	0.272
M46 Other inflammatory spondylopathies	0.726	0.274
M47.9 Spondylosis, unspecified	0.726	0.274
M24 Other specific joint derangements	0.725	0.275
A41.5 Septicaemia due to other Gram-negative organisms	0.725	0.275
M80-M85 Disorders of bone density and structure	0.723	0.277
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.721	0.279
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.719	0.281
A41.0 Septicaemia due to Staphylococcus aureus	0.717	0.282
S02 Fracture of skull and facial bones	0.717	0.283
C64-C68 Malignant neoplasms of urinary tract	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.716	0.284
T79-T79 Certain early complications of trauma	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
L10-L14 Bullous disorders	0.715	0.285
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.714	0.286
M91-M94 Chondropathies	0.714	0.286
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.712	0.288
T81 Complications of procedures, not elsewhere classified	0.711	0.289
Y43.3 Other antineoplastic drugs	0.711	0.289
L91 Hypertrophic disorders of skin	0.709	0.291
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.708	0.291
Y35-Y36 Legal intervention and operations of war	0.708	0.291
Y10-Y34 Event of undetermined intent	0.708	0.291
Y00-Y09 Assault	0.708	0.291
X85-X99 Assault	0.708	0.291
X60-X84 Intentional self-harm	0.708	0.291
X58-X59 Accidental exposure to other and unspecified factors	0.708	0.291
X50-X57 Overexertion, travel and privation	0.708	0.291
X40-X49 Accidental poisoning by and exposure to noxious substances	0.708	0.291
X30-X39 Exposure to forces of nature	0.708	0.291
X20-X29 Contact with venomous animals and plants	0.708	0.291
X10-X19 Contact with heat and hot substances	0.708	0.291
X00-X09 Exposure to smoke, fire and flames	0.708	0.291
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.708	0.291
W75-W84 Other accidental threats to breathing	0.708	0.291
W65-W74 Accidental drowning and submersion	0.708	0.291
W50-W64 Exposure to animate mechanical forces	0.708	0.291
V98-V99 Other and unspecified transport accidents	0.708	0.291
V95-V97 Air and space transport accidents	0.708	0.291
V90-V94 Water transport accidents	0.708	0.291
V80-V89 Other land transport accidents	0.708	0.291
V70-V79 Bus occupant injured in transport accident	0.708	0.291
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.708	0.291
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.708	0.291
V40-V49 Car occupant injured in transport accident	0.708	0.291
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.708	0.291
V20-V29 Motorcycle rider injured in transport accident	0.708	0.291
V10-V19 Pedal cyclist injured in transport accident	0.708	0.291
V01-V09 Pedestrian injured in transport accident	0.708	0.291
L28 Lichen simplex chronicus and prurigo	0.707	0.292
D37-D48 Neoplasms of uncertain or unknown behaviour	0.706	0.294
L40.9 Psoriasis, unspecified	0.703	0.297
D00-D09 In situ neoplasms	0.701	0.299
S06.2 Diffuse brain injury	0.701	0.299
L92 Granulomatous disorders of skin and subcutaneous tissue	0.700	0.300
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.699	0.301
M20 Acquired deformities of fingers and toes	0.698	0.302
M35 Other systemic involvement of connective tissue	0.696	0.304
M45 Ankylosing spondylitis	0.696	0.304
S50-S59 Injuries to the elbow and forearm	0.696	0.304
Y60-Y69 Misadventures to patients during surgical and medical care	0.696	0.304
L57 Skin changes due to chronic exposure to nonionising radiation	0.692	0.308
S69 Other and unspecified injuries of wrist and hand	0.691	0.309
S68 Traumatic amputation of wrist and hand	0.691	0.309
S67 Crushing injury of wrist and hand	0.691	0.309
S65 Injury of blood vessels at wrist and hand level	0.691	0.309
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.691	0.309
S60 Superficial injury of wrist and hand	0.691	0.309
B99-B99 Other infectious diseases	0.691	0.309
B90-B94 Sequelae of infectious and parasitic diseases	0.691	0.309
B85-B89 Pediculosis, acariasis and other infestations	0.691	0.309
B65-B83 Helminthiases	0.691	0.309
B50-B64 Protozoal diseases	0.691	0.309
B20-B24 Human immunodeficiency virus [HIV] disease	0.691	0.309
B15-B19 Viral hepatitis	0.691	0.309
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.691	0.309
A80-A89 Viral infections of the central nervous system	0.691	0.309
A75-A79 Rickettsioses	0.691	0.309
A70-A74 Other diseases caused by chlamydiae	0.691	0.309
A65-A69 Other spirochaetal diseases	0.691	0.309
A50-A64 Infections with a predominantly sexual mode of transmission	0.691	0.309
A20-A28 Certain zoonotic bacterial diseases	0.691	0.309
A15-A19 Tuberculosis	0.691	0.309
L75 Apocrine sweat disorders	0.691	0.309
L74 Eccrine sweat disorders	0.691	0.309
L73 Other follicular disorders	0.691	0.309
L71 Rosacea	0.691	0.309
L70 Acne	0.691	0.309
L68 Hypertrichosis	0.691	0.309
L67 Hair colour and hair shaft abnormalities	0.691	0.309
L66 Cicatricial alopecia [scarring hair loss]	0.691	0.309
L65 Other nonscarring hair loss	0.691	0.309
L64 Androgenic alopecia	0.691	0.309
L63 Alopecia areata	0.691	0.309
L62 Nail disorders in diseases classified elsewhere	0.691	0.309
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.690	0.310
Y59 Other and unspecified vaccines and biological substances	0.688	0.311
Y58 Bacterial vaccines	0.688	0.311
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.688	0.311
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.688	0.311
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.688	0.311
Y53 Agents primarily affecting the gastro-intestinal system	0.688	0.311
Y52 Agents primarily affecting the cardiovascular system	0.688	0.311
Y50 Central nervous system stimulants, not elsewhere classified	0.688	0.311
Y49 Psychotropic drugs, not elsewhere classified	0.688	0.311
Y48 Anaesthetics and therapeutic gases	0.688	0.311
Y47 Sedatives, hypnotics and antianxiety drugs	0.688	0.311
Y46 Antiepileptics and anti-Parkinsonism drugs	0.688	0.311
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.688	0.311
Y44 Agents primarily affecting blood constituents	0.688	0.311
Y41 Other systemic anti-infectives and antiparasitics	0.688	0.311
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.688	0.312
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.686	0.314
M47.86 Other spondylosis (Lumbar region)	0.686	0.314
M06 Other rheumatoid arthritis	0.685	0.315
S89 Other and unspecified injuries of lower leg	0.684	0.316
L50-L54 Urticaria and erythema	0.684	0.316
C50 Malignant neoplasm of breast	0.684	0.316
S08 Traumatic amputation of part of head	0.684	0.316
S07 Crushing injury of head	0.684	0.316
S05 Injury of eye and orbit	0.684	0.316
S04 Injury of cranial nerves	0.684	0.316
S03 Dislocation, sprain and strain of joints and ligaments of head	0.684	0.316
L89 Decubitus ulcer	0.684	0.316
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.681	0.319
L30.9 Dermatitis, unspecified	0.680	0.320
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.680	0.320
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.679	0.321
M65-M68 Disorders of synovium and tendon	0.678	0.322
M11 Other crystal arthropathies	0.677	0.323
S81 Open wound of lower leg	0.676	0.324
S06.5 Traumatic subdural haemorrhage	0.675	0.325
L00-L08 Infections of the skin and subcutaneous tissue	0.673	0.327
S01.3 Open wound of ear	0.672	0.328
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.672	0.328
M34 Systemic sclerosis	0.672	0.328
M33 Dermatopolymyositis	0.672	0.328
M32 Systemic lupus erythematosus	0.672	0.328
M31 Other necrotising vasculopathies	0.672	0.328
M30 Polyarteritis nodosa and related conditions	0.672	0.328
M21 Other acquired deformities of limbs	0.672	0.328
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.672	0.328
L72.2 Steatocystoma multiplex	0.672	0.328
M47.1 Other spondylosis with myelopathy	0.672	0.328
M47.0 Anterior spinal and vertebral artery compression syndromes	0.672	0.328
M10.9 Gout, unspecified	0.668	0.331
M70-M79 Other soft tissue disorders	0.668	0.332
W19 Unspecified fall	0.668	0.332
H43 Disorders of vitreous body	0.667	0.333
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.667	0.333
S70-S79 Injuries to the hip and thigh	0.666	0.334
M47.87 Other spondylosis (Lumbosacral region)	0.666	0.334
S09 Other and unspecified injuries of head	0.665	0.335
T87 Complications peculiar to reattachment and amputation	0.664	0.336
T86 Failure and rejection of transplanted organs and tissues	0.664	0.336
T80 Complications following infusion, transfusion and therapeutic injection	0.664	0.336
A49 Bacterial infection of unspecified site	0.663	0.337
A48 Other bacterial diseases, not elsewhere classified	0.663	0.337
A44 Bartonellosis	0.663	0.337
A43 Nocardiosis	0.663	0.337
A42 Actinomycosis	0.663	0.337
A40 Streptococcal septicaemia	0.663	0.337
A39 Meningococcal infection	0.663	0.337
A37 Whooping cough	0.663	0.337
A36 Diphtheria	0.663	0.337
A32 Listeriosis	0.663	0.337
A31 Infection due to other mycobacteria	0.663	0.337
A30 Leprosy [Hansen's disease]	0.663	0.337
A46 Erysipelas	0.663	0.337
A38 Scarlet fever	0.663	0.337
A35 Other tetanus	0.663	0.337
A34 Obstetrical tetanus	0.663	0.337
A33 Tetanus neonatorum	0.663	0.337
S01.9 Open wound of head, part unspecified	0.662	0.337
L85 Other epidermal thickening	0.661	0.339
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.661	0.339
H65-H75 Diseases of middle ear and mastoid	0.660	0.339
M22 Disorders of patella	0.660	0.340
B37 Candidiasis	0.660	0.340
Y42.7 Androgens and anabolic congeners	0.659	0.341
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.657	0.343
S42 Fracture of shoulder and upper arm	0.656	0.344
C60-C63 Malignant neoplasms of male genital organs	0.656	0.344
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.655	0.344
Y57.9 Drug or medicament, unspecified	0.654	0.346
M20.5 Other deformities of toe(s) (acquired)	0.653	0.347
Y40.8 Other systemic antibiotics	0.651	0.349
M23.3 Other meniscus derangements	0.650	0.350
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.648	0.352
B97 Viral agents as the cause of diseases classified to other chapters	0.647	0.353
S06.6 Traumatic subarachnoid haemorrhage	0.646	0.354
C15-C26 Malignant neoplasms of digestive organs	0.645	0.355
S01.0 Open wound of scalp	0.644	0.356
M49.5 Collapsed vertebra in diseases classified elsewhere	0.643	0.357
A41.8 Other specified septicaemia	0.643	0.357
A41.4 Septicaemia due to anaerobes	0.643	0.357
A41.3 Septicaemia due to Haemophilus influenzae	0.643	0.357
A41.2 Septicaemia due to unspecified staphylococcus	0.643	0.357
A41.1 Septicaemia due to other specified staphylococcus	0.643	0.357
S00.1 Contusion of eyelid and periocular area	0.643	0.357
M47.89 Other spondylosis (Site unspecified)	0.641	0.359
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.641	0.359
M47.85 Other spondylosis (Thoracolumbar region)	0.641	0.359
M47.84 Other spondylosis (Thoracic region)	0.641	0.359
M47.83 Other spondylosis (Cervicothoracic region)	0.641	0.359
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.641	0.359
S61.0 Open wound of finger(s) without damage to nail	0.641	0.359
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.640	0.360
Chapter XIV Diseases of the genitourinary system	0.640	0.360
S64.9 Injury of unspecified nerve at wrist and hand level	0.637	0.363
S64.8 Injury of other nerves at wrist and hand level	0.637	0.363
S64.7 Injury of multiple nerves at wrist and hand level	0.637	0.363
S64.3 Injury of digital nerve of thumb	0.637	0.363
S64.2 Injury of radial nerve at wrist and hand level	0.637	0.363
S64.1 Injury of median nerve at wrist and hand level	0.637	0.363
S64.0 Injury of ulnar nerve at wrist and hand level	0.637	0.363
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.634	0.366
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.634	0.366
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.634	0.366
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.634	0.366
C40-C41 Malignant neoplasms of bone and articular cartilage	0.634	0.366
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.634	0.366
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.634	0.366
L95 Vasculitis limited to skin, not elsewhere classified	0.634	0.366
L94 Other localised connective tissue disorders	0.634	0.366
L93 Lupus erythematosus	0.634	0.366
L87 Transepidermal elimination disorders	0.634	0.366
L81 Other disorders of pigmentation	0.634	0.366
L88 Pyoderma gangrenosum	0.634	0.366
L86 Keratoderma in diseases classified elsewhere	0.634	0.366
L83 Acanthosis nigricans	0.634	0.366
L80 Vitiligo	0.634	0.366
Chapter VI Diseases of the nervous system	0.634	0.366
Y40.0 Penicillins	0.633	0.366
W07 Fall involving chair	0.633	0.367
H25-H28 Disorders of lens	0.633	0.367
L29 Pruritus	0.632	0.368
L25 Unspecified contact dermatitis	0.632	0.368
L24 Irritant contact dermatitis	0.632	0.368
L23 Allergic contact dermatitis	0.632	0.368
L21 Seborrhoeic dermatitis	0.632	0.368
L20 Atopic dermatitis	0.632	0.368
L26 Exfoliative dermatitis	0.632	0.368
L22 Diaper [napkin] dermatitis	0.632	0.368
Y42.5 Other oestrogens and progestogens	0.632	0.368
L27 Dermatitis due to substances taken internally	0.631	0.369
T82.1 Mechanical complication of cardiac electronic device	0.630	0.370
M14 Arthropathies in other diseases classified elsewhere	0.630	0.370
M12 Other specific arthropathies	0.630	0.370
M09 Juvenile arthritis in diseases classified elsewhere	0.630	0.370
M08 Juvenile arthritis	0.630	0.370
M07 Psoriatic and enteropathic arthropathies	0.630	0.370
M05 Seropositive rheumatoid arthritis	0.630	0.370
S61.1 Open wound of finger(s) with damage to nail	0.628	0.372
A00-A09 Intestinal infectious diseases	0.628	0.372
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.628	0.372
H55-H59 Other disorders of eye and adnexa	0.621	0.379
H46-H48 Disorders of optic nerve and visual pathways	0.621	0.379
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.621	0.379
H10-H13 Disorders of conjunctiva	0.621	0.379
C83 Diffuse non-Hodgkin's lymphoma	0.619	0.381
B25-B34 Other viral diseases	0.618	0.382
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.617	0.383
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.616	0.384
L44 Other papulosquamous disorders	0.616	0.384
L41 Parapsoriasis	0.616	0.384
L45 Papulosquamous disorders in diseases classified elsewhere	0.616	0.384
L42 Pityriasis rosea	0.616	0.384
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.615	0.385
L43 Lichen planus	0.615	0.385
W25 Contact with sharp glass	0.613	0.387
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.611	0.389
S82 Fracture of lower leg, including ankle	0.609	0.390
M13 Other arthritis	0.609	0.391
S62.8 Fracture of other and unspecified parts of wrist and hand	0.609	0.391
S00.9 Superficial injury of head, part unspecified	0.609	0.391
M23.9 Internal derangement of knee, unspecified	0.608	0.392
M23.6 Other spontaneous disruption of ligament(s) of knee	0.608	0.392
M23.5 Chronic instability of knee	0.608	0.392
M23.4 Loose body in knee	0.608	0.392
M23.1 Discoid meniscus (congenital)	0.608	0.392
M23.0 Cystic meniscus	0.608	0.392
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.607	0.392
L90 Atrophic disorders of skin	0.606	0.394
H60-H62 Diseases of external ear	0.605	0.395
C43-C44 Melanoma and other malignant neoplasms of skin	0.605	0.395
C50.2 Upper-inner quadrant of breast	0.603	0.397
S88 Traumatic amputation of lower leg	0.603	0.397
S87 Crushing injury of lower leg	0.603	0.397
S86 Injury of muscle and tendon at lower leg level	0.603	0.397
S85 Injury of blood vessels at lower leg level	0.603	0.397
S84 Injury of nerves at lower leg level	0.603	0.397
S06.9 Intracranial injury, unspecified	0.603	0.397
S06.8 Other intracranial injuries	0.603	0.397
S06.7 Intracranial injury with prolonged coma	0.603	0.397
S06.4 Epidural haemorrhage	0.603	0.397
S06.3 Focal brain injury	0.603	0.397
S06.1 Traumatic cerebral oedema	0.603	0.397
S06.0 Concussion	0.603	0.397
S80 Superficial injury of lower leg	0.603	0.397
M15-M19 Arthrosis	0.602	0.398
L57.0 Actinic keratosis	0.601	0.399
M23.8 Other internal derangements of knee	0.601	0.399
M54 Dorsalgia	0.600	0.400
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.600	0.400
S06.20 Diffuse brain injury (without open intracranial wound)	0.600	0.400
H43.1 Vitreous haemorrhage	0.600	0.400
C90 Multiple myeloma and malignant plasma cell neoplasms	0.600	0.400
W29 Contact with other powered hand tools and household machinery	0.599	0.401
Y42.9 Other and unspecified hormone antagonists	0.597	0.403
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.597	0.403
Y42.4 Oral contraceptives	0.597	0.403
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.597	0.403
Y42.2 Antithyroid drugs	0.597	0.403
Y42.1 Thyroid hormones and substitutes	0.597	0.403
Y42.0 Glucocorticoids and synthetic analogs	0.597	0.403
S20 Superficial injury of thorax	0.592	0.408
H80-H83 Diseases of inner ear	0.591	0.409
W22 Striking against or struck by other objects	0.591	0.409
S01.7 Multiple open wounds of head	0.590	0.410
S01.4 Open wound of cheek and temporomandibular area	0.590	0.410
S01.2 Open wound of nose	0.590	0.410
S01.1 Open wound of eyelid and periocular area	0.590	0.410
C64 Malignant neoplasm of kidney, except renal pelvis	0.590	0.410
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.588	0.411
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.588	0.412
T85.2 Mechanical complication of intraocular lens	0.588	0.412
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.587	0.413
L58 Radiodermatitis	0.587	0.413
L56 Other acute skin changes due to ultraviolet radiation	0.587	0.413
L55 Sunburn	0.587	0.413
W18 Other fall on same level	0.587	0.413
W17 Other fall from one level to another	0.587	0.413
W16 Diving or jumping into water causing injury other than drowning or submersion	0.587	0.413
W15 Fall from cliff	0.587	0.413
W14 Fall from tree	0.587	0.413
W13 Fall from, out of or through building or structure	0.587	0.413
W12 Fall on and from scaffolding	0.587	0.413
W11 Fall on and from ladder	0.587	0.413
W10 Fall on and from stairs and steps	0.587	0.413
W09 Fall involving playground equipment	0.587	0.413
W08 Fall involving other furniture	0.587	0.413
W06 Fall involving bed	0.587	0.413
W05 Fall involving wheelchair	0.587	0.413
W04 Fall while being carried or supported by other persons	0.587	0.413
W03 Other fall on same level due to collision with, or pushing by, another person	0.587	0.413
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.587	0.413
W01 Fall on same level from slipping, tripping and stumbling	0.587	0.413
W00 Fall on same level involving ice and snow	0.587	0.413
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.587	0.413
H02 Other disorders of eyelid	0.587	0.413
C92 Myeloid leukaemia	0.585	0.415
Y43.9 Primarily systemic agent, unspecified	0.584	0.416
Y43.8 Other primarily systemic agents, not elsewhere classified	0.584	0.416
Y43.6 Enzymes, not elsewhere classified	0.584	0.416
Y43.5 Acidifying and alkalising agents	0.584	0.416
Y43.4 Immunosuppressive agents	0.584	0.416
Y43.2 Antineoplastic natural products	0.584	0.416
Y43.1 Antineoplastic antimetabolites	0.584	0.416
Y43.0 Antiallergic and antiemetic drugs	0.584	0.416
C50.8 Overlapping lesion of breast	0.584	0.416
S62.3 Fracture of other metacarpal bone	0.584	0.416
M10.99 Gout, unspecified (Site unspecified)	0.583	0.417
L28.0 Lichen simplex chronicus	0.583	0.417
L91.8 Other hypertrophic disorders of skin	0.583	0.417
H40-H42 Glaucoma	0.583	0.417
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.582	0.418
M25.7 Osteophyte	0.582	0.418
W19.9 Unspecified place	0.581	0.419
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.580	0.419
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.580	0.419
T82.4 Mechanical complication of vascular dialysis catheter	0.580	0.419
T82.3 Mechanical complication of other vascular grafts	0.580	0.419
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.580	0.419
T82.0 Mechanical complication of heart valve prosthesis	0.580	0.419
D45 Polycythaemia vera	0.581	0.419
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.578	0.421
S49 Other and unspecified injuries of shoulder and upper arm	0.576	0.424
S48 Traumatic amputation of shoulder and upper arm	0.576	0.424
S46 Injury of muscle and tendon at shoulder and upper arm level	0.576	0.424
S45 Injury of blood vessels at shoulder and upper arm level	0.576	0.424
S44 Injury of nerves at shoulder and upper arm level	0.576	0.424
S41 Open wound of shoulder and upper arm	0.576	0.424
S40 Superficial injury of shoulder and upper arm	0.576	0.424
S47 Crushing injury of shoulder and upper arm	0.576	0.424
Y40.9 Systemic antibiotic, unspecified	0.575	0.424
Y40.7 Antifungal antibiotics, systemically used	0.575	0.424
Y40.6 Rifamycins	0.575	0.424
Y40.5 Aminoglycosides	0.575	0.424
Y40.4 Tetracyclines	0.575	0.424
Y40.3 Macrolides	0.575	0.424
Y40.2 Chloramphenicol group	0.575	0.424
Y40.1 Cefalosporins and other -lactam antibiotics	0.575	0.424
S01.8 Open wound of other parts of head	0.574	0.426
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.574	0.426
D06 Carcinoma in situ of cervix uteri	0.574	0.426
M24.1 Other articular cartilage disorders	0.573	0.427
Chapter IX Diseases of the circulatory system	0.573	0.427
S89.9 Unspecified injury of lower leg	0.572	0.428
M25.5 Pain in joint	0.572	0.428
S01.5 Open wound of lip and oral cavity	0.571	0.429
L03 Cellulitis	0.571	0.429
T83.0 Mechanical complication of urinary (indwelling) catheter	0.570	0.430
T36-T50 Poisoning by drugs, medicaments and biological substances	0.570	0.430
S61.7 Multiple open wounds of wrist and hand	0.569	0.430
S22 Fracture of rib(s), sternum and thoracic spine	0.569	0.431
W49 Exposure to other and unspecified inanimate mechanical forces	0.568	0.431
W46 Contact with hypodermic needle	0.568	0.431
W45 Foreign body or object entering through skin	0.568	0.431
W44 Foreign body entering into or through eye or natural orifice	0.568	0.431
W43 Exposure to vibration	0.568	0.431

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations