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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs206017
log Bayes Factor = 112.148
Chromosome 6   position 32,176,211  (GRCh37) Explore rs206017 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
0.998 0.002 0.000
G37 Other demyelinating diseases of central nervous system
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
E10.1 With ketoacidosis
0.000 0.010 0.990
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.025 0.975
E10.3 With ophthalmic complications
0.000 0.041 0.959
E16 Other disorders of pancreatic internal secretion
0.000 0.043 0.957
E14 Unspecified diabetes mellitus
0.000 0.044 0.956
E11.1 With ketoacidosis
0.000 0.054 0.946
I10 Essential (primary) hypertension
0.000 0.062 0.938
E11.2 With renal complications
0.000 0.070 0.930
E16.2 Hypoglycaemia, unspecified
0.000 0.074 0.926
E13 Other specified diabetes mellitus
0.000 0.079 0.921
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.082 0.918
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.913 0.087 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.087 0.913
E14.3 With ophthalmic complications
0.000 0.122 0.878
E13.9 Without complications
0.000 0.123 0.877
G37.8 Other specified demyelinating diseases of central nervous system
0.845 0.155 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.158 0.842
E10.8 With unspecified complications
0.000 0.167 0.833
E16.1 Other hypoglycaemia
0.000 0.174 0.826
G36 Other acute disseminated demyelination
0.822 0.178 0.000
E11.3 With ophthalmic complications
0.000 0.193 0.807
E14.8 With unspecified complications
0.000 0.198 0.802
E24 Cushing's syndrome
0.000 0.199 0.801
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.208 0.792
E14.1 With ketoacidosis
0.000 0.213 0.787
E29 Testicular dysfunction
0.000 0.216 0.784
E21.3 Hyperparathyroidism, unspecified
0.000 0.217 0.783
E11.0 With coma
0.000 0.222 0.778
E10.0 With coma
0.000 0.222 0.777
E28 Ovarian dysfunction
0.000 0.229 0.771
E40-E46 Malnutrition
0.000 0.240 0.760
E14.4 With neurological complications
0.000 0.244 0.756
E10.6 With other specified complications
0.000 0.255 0.744
E11.5 With peripheral circulatory complications
0.000 0.258 0.742
E03.8 Other specified hypothyroidism
0.000 0.265 0.735
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.273 0.727
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.275 0.725
E14.9 Without complications
0.000 0.277 0.723
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
G37.5 Concentric sclerosis [Balo]
0.715 0.285 0.000
G37.4 Subacute necrotising myelitis
0.715 0.285 0.000
G37.2 Central pontine myelinolysis
0.715 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.715 0.285 0.000
G37.0 Diffuse sclerosis
0.715 0.285 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.293 0.707
E10.7 With multiple complications
0.000 0.294 0.706
E24.2 Drug-induced Cushing's syndrome
0.000 0.300 0.700
E15 Nondiabetic hypoglycaemic coma
0.000 0.301 0.699
G36.0 Neuromyelitis optica [Devic]
0.697 0.303 0.000
E10.2 With renal complications
0.000 0.306 0.694
E14.2 Withrenal complications
0.000 0.307 0.693
E29.1 Testicular hypofunction
0.000 0.309 0.691
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.314 0.686
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.314 0.686
E16.4 Abnormal secretion of gastrin
0.000 0.314 0.686
E16.3 Increased secretion of glucagon
0.000 0.314 0.686
E14.7 With multiple complications
0.000 0.314 0.686
E25 Adrenogenital disorders
0.000 0.319 0.681
E28.2 Polycystic ovarian syndrome
0.000 0.324 0.676
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.331 0.669
E13.8 With unspecified complications
0.000 0.340 0.660
E13.7 With multiple complications
0.000 0.340 0.660
E13.6 With other specified complications
0.000 0.340 0.660
E13.5 With peripheral circulatory complications
0.000 0.340 0.660
E13.4 With neurological complications
0.000 0.340 0.660
E13.2 With renal complications
0.000 0.340 0.660
E13.1 With ketoacidosis
0.000 0.340 0.660
E13.0 With coma
0.000 0.340 0.660
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.341 0.659
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.345 0.655
E32 Diseases of thymus
0.000 0.345 0.655
E30 Disorders of puberty, not elsewhere classified
0.000 0.345 0.655
E21.2 Other hyperparathyroidism
0.000 0.346 0.654
E10.5 With peripheral circulatory complications
0.000 0.348 0.652
E31 Polyglandular dysfunction
0.000 0.351 0.649
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.356 0.644
E14.0 With coma
0.000 0.360 0.640
E23 Hypofunction and other disorders of pituitary gland
0.000 0.365 0.635
K51.9 Ulcerative colitis, unspecified
0.632 0.368 0.000
E05.8 Other thyrotoxicosis
0.000 0.368 0.632
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.371 0.628
E10.4 With neurological complications
0.000 0.378 0.622
E24.9 Cushing's syndrome, unspecified
0.000 0.382 0.618
E24.0 Pituitary-dependent Cushing's disease
0.000 0.382 0.618
K51 Ulcerative colitis
0.617 0.383 0.000
E34 Other endocrine disorders
0.000 0.390 0.610
K51.3 Ulcerative (chronic) rectosigmoiditis
0.604 0.396 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.396 0.604
E22 Hyperfunction of pituitary gland
0.000 0.400 0.600
G36.9 Acute disseminated demyelination, unspecified
0.590 0.410 0.000
G36.8 Other specified acute disseminated demyelination
0.590 0.410 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.590 0.410 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.411 0.589
E13.3 With ophthalmic complications
0.000 0.416 0.583
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.426 0.574
E24.3 Ectopic ACTH syndrome
0.000 0.426 0.574
E24.1 Nelson's syndrome
0.000 0.426 0.574
E20 Hypoparathyroidism
0.000 0.426 0.574
E11.8 With unspecified complications
0.000 0.435 0.565
E07 Other disorders of thyroid
0.000 0.437 0.563
E29.9 Testicular dysfunction, unspecified
0.000 0.438 0.562
E29.8 Other testicular dysfunction
0.000 0.438 0.562
E29.0 Testicular hyperfunction
0.000 0.438 0.562
K51.8 Other ulcerative colitis
0.558 0.442 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.447 0.553
E28.8 Other ovarian dysfunction
0.000 0.447 0.553
E28.1 Androgen excess
0.000 0.447 0.553
E28.0 Oestrogen excess
0.000 0.447 0.553
E65-E68 Obesity and other hyperalimentation
0.000 0.452 0.548
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.455 0.545
E45 Retarded development following protein-energy malnutrition
0.000 0.455 0.545
E43 Unspecified severe protein-energy malnutrition
0.000 0.455 0.545
E42 Marasmic kwashiorkor
0.000 0.455 0.545
E41 Nutritional marasmus
0.000 0.455 0.545
E40 Kwashiorkor
0.000 0.455 0.545
K51.5 Mucosal proctocolitis
0.545 0.455 0.000
J45.9 Asthma, unspecified
0.000 0.460 0.540
E28.3 Primary ovarian failure
0.000 0.462 0.538
E23.2 Diabetes insipidus
0.000 0.464 0.536
E24.8 Other Cushing's syndrome
0.000 0.477 0.523
E11.6 With other specified complications
0.000 0.479 0.521
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E14.6 With other specified complications
0.000 0.500 0.500
K51.4 Pseudopolyposis of colon
0.495 0.505 0.000
E26 Hyperaldosteronism
0.000 0.506 0.493
E25.9 Adrenogenital disorder, unspecified
0.000 0.512 0.488
E25.8 Other adrenogenital disorders
0.000 0.512 0.488
E22.1 Hyperprolactinaemia
0.000 0.512 0.488
E23.6 Other disorders of pituitary gland
0.000 0.513 0.487
E23.7 Disorder of pituitary gland, unspecified
0.000 0.514 0.486
E34.8 Other specified endocrine disorders
0.000 0.514 0.485
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.520 0.480
E06 Thyroiditis
0.000 0.530 0.470
E30.9 Disorder of puberty, unspecified
0.000 0.530 0.469
E30.8 Other disorders of puberty
0.000 0.530 0.469
E30.1 Precocious puberty
0.000 0.530 0.469
E30.0 Delayed puberty
0.000 0.530 0.469
E32.9 Disease of thymus, unspecified
0.000 0.530 0.469
E32.8 Other diseases of thymus
0.000 0.530 0.469
E32.1 Abscess of thymus
0.000 0.530 0.469
E32.0 Persistent hyperplasia of thymus
0.000 0.530 0.469
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.530 0.469
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.530 0.469
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.530 0.469
E31.9 Polyglandular dysfunction, unspecified
0.000 0.535 0.465
E31.8 Other polyglandular dysfunction
0.000 0.535 0.465
E31.1 Polyglandular hyperfunction
0.000 0.535 0.465
E31.0 Autoimmune polyglandular failure
0.000 0.541 0.459
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.545 0.455
E23.1 Drug-induced hypopituitarism
0.000 0.545 0.455
K51.2 Ulcerative (chronic) proctitis
0.443 0.557 0.000
E34.5 Androgen resistance syndrome
0.000 0.562 0.438
E34.4 Constitutional tall stature
0.000 0.562 0.438
E34.3 Short stature, not elsewhere classified
0.000 0.562 0.438
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.562 0.438
E34.1 Other hypersecretion of intestinal hormones
0.000 0.562 0.438
E07.8 Other specified disorders of thyroid
0.000 0.563 0.437
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.569 0.430
E22.8 Other hyperfunction of pituitary gland
0.000 0.569 0.430
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.585 0.415
E20.1 Pseudohypoparathyroidism
0.000 0.588 0.412
E20.0 Idiopathic hypoparathyroidism
0.000 0.588 0.412
E07.1 Dyshormogenetic goitre
0.000 0.596 0.404
E07.0 Hypersecretion of calcitonin
0.000 0.596 0.404
E65 Localised adiposity
0.000 0.597 0.403
E67 Other hyperalimentation
0.000 0.607 0.393
E68 Sequelae of hyperalimentation
0.000 0.607 0.393
E44.1 Mild protein-energy malnutrition
0.000 0.609 0.391
E44.0 Moderate protein-energy malnutrition
0.000 0.609 0.391
E34.0 Carcinoid syndrome
0.000 0.614 0.386
E20.9 Hypoparathyroidism, unspecified
0.000 0.619 0.380
E34.9 Endocrine disorder, unspecified
0.000 0.620 0.380
E20.8 Other hypoparathyroidism
0.000 0.630 0.370
E26.8 Other hyperaldosteronism
0.000 0.646 0.354
E26.1 Secondary hyperaldosteronism
0.000 0.646 0.354
E06.4 Drug-induced thyroiditis
0.000 0.663 0.337
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.663 0.337
E06.1 Subacute thyroiditis
0.000 0.663 0.337
E06.0 Acute thyroiditis
0.000 0.663 0.337
E06.5 Other chronic thyroiditis
0.000 0.663 0.336
K51.1 Ulcerative (chronic) ileocolitis
0.336 0.664 0.000
K90 Intestinal malabsorption
0.000 0.668 0.332
E26.9 Hyperaldosteronism, unspecified
0.000 0.688 0.311
I10-I15 Hypertensive diseases
0.000 0.692 0.308
K51.0 Ulcerative (chronic) enterocolitis
0.305 0.695 0.000
E50-E64 Other nutritional deficiencies
0.002 0.698 0.300
E22.0 Acromegaly and pituitary gigantism
0.000 0.709 0.291
E06.9 Thyroiditis, unspecified
0.000 0.714 0.286
E67.8 Other specified hyperalimentation
0.000 0.718 0.282
E67.3 Hypervitaminosis D
0.000 0.718 0.282
E67.2 Megavitamin-B6 syndrome
0.000 0.718 0.282
E67.1 Hypercarotenaemia
0.000 0.718 0.282
E67.0 Hypervitaminosis A
0.000 0.718 0.282
E27 Other disorders of adrenal gland
0.000 0.721 0.279
E26.0 Primary hyperaldosteronism
0.000 0.737 0.263
K90.9 Intestinal malabsorption, unspecified
0.000 0.761 0.239
K90.3 Pancreatic steatorrhoea
0.000 0.762 0.238
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.762 0.238
K90.1 Tropical sprue
0.000 0.762 0.238
I15 Secondary hypertension
0.000 0.766 0.234
E64 Sequelae of malnutrition and other nutritional deficiencies
0.002 0.783 0.215
E50 Vitamin A deficiency
0.002 0.783 0.215
E60 Dietary zinc deficiency
0.002 0.783 0.215
E59 Dietary selenium deficiency
0.002 0.783 0.215
E54 Ascorbic acid deficiency
0.002 0.783 0.215
E52 Niacin deficiency [pellagra]
0.002 0.783 0.215
K90.8 Other intestinal malabsorption
0.000 0.785 0.215
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.787 0.213
E51 Thiamine deficiency
0.002 0.788 0.210
E27.9 Disorder of adrenal gland, unspecified
0.000 0.788 0.211
E21.0 Primary hyperparathyroidism
0.000 0.789 0.211
E56 Other vitamin deficiencies
0.002 0.790 0.209
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.793 0.207
I13 Hypertensive heart and renal disease
0.000 0.795 0.205
I11 Hypertensive heart disease
0.000 0.796 0.204
L40.9 Psoriasis, unspecified
0.000 0.797 0.203
E66 Obesity
0.000 0.798 0.202
E63 Other nutritional deficiencies
0.002 0.799 0.199
E53 Deficiency of other B group vitamins
0.002 0.799 0.199
E11.4 With neurological complications
0.000 0.799 0.201
E27.5 Adrenomedullary hyperfunction
0.000 0.799 0.200
E27.0 Other adrenocortical overactivity
0.000 0.799 0.200
E06.3 Autoimmune thyroiditis
0.000 0.803 0.197
E61 Deficiency of other nutrient elements
0.001 0.804 0.195
L40 Psoriasis
0.000 0.808 0.192
L40.0 Psoriasis vulgaris
0.000 0.820 0.180
E58 Dietary calcium deficiency
0.002 0.825 0.173
I15.0 Renovascular hypertension
0.000 0.827 0.173
I15.1 Hypertension secondary to other renal disorders
0.000 0.827 0.173
I15.9 Seconday hypertension, unspecified
0.000 0.827 0.173
Z93.2 Ileostomy status
0.172 0.828 0.000
I15.8 Other secondary hypertension
0.000 0.832 0.168
I15.2 Hypertension secondary to endocrine disorders
0.000 0.832 0.168
E07.9 Disorder of thyroid, unspecified
0.000 0.832 0.168
L40.5 Arthropathic psoriasis
0.000 0.833 0.167
E53.8 Deficiency of other specified B group vitamins
0.000 0.835 0.165
I12 Hypertensive renal disease
0.000 0.836 0.164
E66.9 Obesity, unspecified
0.000 0.836 0.164
E27.8 Other specified disorders of adrenal gland
0.000 0.839 0.161
L40.1 Generalised pustular psoriasis
0.000 0.843 0.157
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.844 0.156
E50.9 Vitamin A deficiency, unspecified
0.001 0.844 0.154
E50.8 Other manifestations of vitamin A deficiency
0.001 0.844 0.154
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.844 0.154
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.844 0.154
E50.5 Vitamin A deficiency with night blindness
0.001 0.844 0.154
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.844 0.154
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.844 0.154
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.844 0.154
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.844 0.154
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.844 0.154
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.844 0.154
E64.8 Sequelae of other nutritional deficiencies
0.001 0.844 0.154
E64.3 Sequelae of rickets
0.001 0.844 0.154
E64.2 Sequelae of vitamin C deficiency
0.001 0.844 0.154
E64.1 Sequelae of vitamin A deficiency
0.001 0.844 0.154
E64.0 Sequelae of protein-energy malnutrition
0.001 0.844 0.154
E51.9 Thiamine deficiency, unspecified
0.001 0.848 0.151
E51.8 Other manifestations of thiamine deficiency
0.001 0.848 0.151
E51.1 Beriberi
0.001 0.848 0.151
E27.1 Primary adrenocortical insufficiency
0.000 0.848 0.152
E56.9 Vitamin deficiency, unspecified
0.001 0.849 0.150
E56.8 Deficiency of other vitamins
0.001 0.849 0.150
E56.0 Deficiency of vitamin E
0.001 0.849 0.150
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.850 0.149
E51.2 Wernicke's encephalopathy
0.001 0.852 0.146
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.853 0.147
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.853 0.147
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.853 0.147
L40.3 Pustulosis palmaris et plantaris
0.000 0.853 0.147
E66.1 Drug-induced obesity
0.000 0.855 0.145
E63.8 Other specified nutritional deficiencies
0.002 0.855 0.143
E63.1 Imbalance of constituents of food intake
0.002 0.855 0.143
E63.0 Essential fatty acid [EFA] deficiency
0.002 0.855 0.143
E56.1 Deficiency of vitamin K
0.001 0.855 0.143
E53.1 Pyridoxine deficiency
0.001 0.856 0.143
E53.0 Riboflavin deficiency
0.001 0.856 0.143
E61.1 Iron deficiency
0.000 0.859 0.141
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.859 0.141
E61.9 Deficiency of nutrient element, unspecified
0.001 0.859 0.140
E61.8 Deficiency of other specified nutrient elements
0.001 0.859 0.140
E61.7 Deficiency of multiple nutrient elements
0.001 0.859 0.140
E61.6 Vanadium deficiency
0.001 0.859 0.140
E61.5 Molybdenum deficiency
0.001 0.859 0.140
E61.4 Chromium deficiency
0.001 0.859 0.140
E61.3 Manganese deficiency
0.001 0.859 0.140
E61.0 Copper deficiency
0.001 0.859 0.140
A04.7 Enterocolitis due to Clostridium difficile
0.141 0.859 0.000
I74 Arterial embolism and thrombosis
0.000 0.860 0.140
L40.8 Other psoriasis
0.000 0.860 0.140
L40.4 Guttate psoriasis
0.000 0.862 0.138
L40.2 Acrodermatitis continua
0.000 0.862 0.138
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.863 0.137
E27.2 Addisonian crisis
0.000 0.864 0.136
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.864 0.136
E55 Vitamin D deficiency
0.004 0.866 0.130
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.869 0.130
E63.9 Nutritional deficiency, unspecified
0.002 0.871 0.127
L90.0 Lichen sclerosus et atrophicus
0.000 0.871 0.129
I74.8 Embolism and thrombosis of other arteries
0.000 0.877 0.123
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.879 0.121
E61.2 Magnesium deficiency
0.001 0.880 0.118
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.885 0.115
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.887 0.113
E23.0 Hypopituitarism
0.001 0.894 0.105
J45 Asthma
0.000 0.899 0.101
I12.0 Hypertensive renal disease with renal failure
0.000 0.902 0.098
E55.0 Rickets, active
0.003 0.904 0.093
I74.5 Embolism and thrombosis of iliac artery
0.000 0.907 0.093
I12.9 Hypertensive renal disease without renal failure
0.000 0.908 0.092
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.909 0.091
E83.1 Disorders of iron metabolism
0.089 0.911 0.000
I72 Other aneurysm
0.000 0.913 0.087
I72.4 Aneurysm of artery of lower extremity
0.000 0.913 0.087
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.914 0.086
E66.0 Obesity due to excess calories
0.000 0.914 0.085
E53.9 Vitamin B deficiency, unspecified
0.002 0.915 0.083
Chapter IX Diseases of the circulatory system
0.000 0.921 0.079
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.921 0.079
M45.X9 Ankylosing spondylitis (Site unspecified)
0.078 0.922 0.000
I20-I25 Ischaemic heart diseases
0.000 0.926 0.074
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.926 0.074
E04 Other non-toxic goitre
0.000 0.927 0.073
I24 Other acute ischaemic heart diseases
0.000 0.928 0.072
J45.1 Nonallergic asthma
0.000 0.929 0.071
I22 Subsequent myocardial infarction
0.000 0.931 0.069
I72.9 Aneurysm of unspecified site
0.000 0.931 0.068
I72.3 Aneurysm of iliac artery
0.000 0.933 0.067
J45.8 Mixed asthma
0.000 0.934 0.066
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.935 0.065
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.936 0.064
I72.1 Aneurysm of artery of upper extremity
0.000 0.937 0.063
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.938 0.062
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.938 0.062
I73 Other peripheral vascular diseases
0.000 0.938 0.062
I72.2 Aneurysm of renal artery
0.000 0.939 0.061
M45 Ankylosing spondylitis
0.061 0.939 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.941 0.059
I00-I02 Acute rheumatic fever
0.000 0.942 0.058
I73.9 Peripheral vascular disease, unspecified
0.000 0.942 0.058
I23 Certain current complications following acute myocardial infarction
0.000 0.942 0.057
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.943 0.057
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.944 0.056
M45.X2 Ankylosing spondylitis (Cervical region)
0.053 0.947 0.000
E04.8 Other specified non-toxic goitre
0.000 0.947 0.052
K50-K52 Noninfective enteritis and colitis
0.052 0.948 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.052 0.948 0.000
I77 Other disorders of arteries and arterioles
0.000 0.949 0.051
I20 Angina pectoris
0.000 0.951 0.049
I72.8 Aneurysm of other specified arteries
0.000 0.951 0.049
L40-L45 Papulosquamous disorders
0.000 0.952 0.048
I70 Atherosclerosis
0.000 0.952 0.048
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.953 0.047
I20.0 Unstable angina
0.000 0.954 0.046
E04.0 Non-toxic diffuse goitre
0.000 0.954 0.046
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.954 0.046
I79.1 Aortitis in diseases classified elsewhere
0.000 0.954 0.046
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.954 0.046
M45.X6 Ankylosing spondylitis (Lumbar region)
0.046 0.954 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.954 0.045
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.955 0.045
I72.0 Aneurysm of carotid artery
0.000 0.956 0.044
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.956 0.044
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.044 0.956 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.044 0.956 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.044 0.956 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.044 0.956 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.044 0.956 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.044 0.956 0.000
I22.8 Subsequent myocardial infarction of other sites
0.000 0.956 0.043
I25 Chronic ischaemic heart disease
0.000 0.957 0.043
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.957 0.043
I00 Rheumatic fever without mention of heart involvement
0.000 0.958 0.042
E66.8 Other obesity
0.000 0.958 0.042
I71 Aortic aneurysm and dissection
0.000 0.958 0.042
I02 Rheumatic chorea
0.000 0.958 0.041
I01 Rheumatic fever with heart involvement
0.000 0.958 0.041
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.958 0.041
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.958 0.041
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.958 0.041
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.958 0.041
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.958 0.041
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.958 0.041
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.958 0.041
I77.0 Arteriovenous fistula, acquired
0.000 0.959 0.041
I25.5 Ischaemic cardiomyopathy
0.000 0.959 0.041
I24.1 Dressler's syndrome
0.000 0.959 0.041
I73.8 Other specified peripheral vascular diseases
0.000 0.959 0.041
I25.4 Coronary artery aneurysm
0.000 0.960 0.039
I20.1 Angina pectoris with documented spasm
0.000 0.962 0.038
I77.2 Rupture of artery
0.000 0.962 0.037
I77.5 Necrosis of artery
0.000 0.963 0.037
I77.4 Coeliac artery compression syndrome
0.000 0.963 0.037
I70.8 Atherosclerosis of other arteries
0.000 0.964 0.036
I70.0 Atherosclerosis of aorta
0.000 0.964 0.036
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.964 0.036
I24.8 Other forms of acute ischaemic heart disease
0.000 0.964 0.036
L44 Other papulosquamous disorders
0.000 0.965 0.035
L41 Parapsoriasis
0.000 0.965 0.035
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.965 0.035
I77.1 Stricture of artery
0.000 0.966 0.034
I77.3 Arterial fibromuscular dysplasia
0.000 0.966 0.033
I25.6 Silent myocardial ischaemia
0.000 0.967 0.033
I70.9 Generalised and unspecified atherosclerosis
0.000 0.967 0.033
E83 Disorders of mineral metabolism
0.033 0.967 0.000
I70.1 Atherosclerosis of renal artery
0.000 0.967 0.032
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.968 0.032
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.968 0.032
I71.0 Dissection of aorta [any part]
0.000 0.969 0.031
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.969 0.031
J45.0 Predominantly allergic asthma
0.000 0.969 0.031
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.970 0.030
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.970 0.030
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.970 0.030
I01.8 Other acute rheumatic heart disease
0.000 0.970 0.030
I01.2 Acute rheumatic myocarditis
0.000 0.970 0.030
I01.1 Acute rheumatic endocarditis
0.000 0.970 0.030
I01.0 Acute rheumatic pericarditis
0.000 0.970 0.030
I02.9 Rheumatic chorea without heart involvement
0.000 0.970 0.030
I02.0 Rheumatic chorea with heart involvement
0.000 0.970 0.030
E83.3 Disorders of phosphorus metabolism
0.030 0.970 0.000
N48.6 Balanitis xerotica obliterans
0.000 0.970 0.030
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.971 0.029
N48 Other disorders of penis
0.000 0.971 0.029
I25.3 Aneurysm of heart
0.000 0.971 0.029
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.971 0.029
L42 Pityriasis rosea
0.000 0.972 0.028
N48.0 Leukoplakia of penis
0.000 0.972 0.028
L43 Lichen planus
0.000 0.972 0.028
N48.1 Balanoposthitis
0.000 0.972 0.028
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.972 0.027
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.972 0.027
D64.9 Anaemia, unspecified
0.000 0.973 0.027
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.974 0.026
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.974 0.026
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.974 0.026
L41.9 Parapsoriasis, unspecified
0.000 0.975 0.025
L41.8 Other parapsoriasis
0.000 0.975 0.025
L41.5 Retiform parapsoriasis
0.000 0.975 0.025
L41.4 Large plaque parapsoriasis
0.000 0.975 0.025
L41.3 Small plaque parapsoriasis
0.000 0.975 0.025
L41.2 Lymphomatoid papulosis
0.000 0.975 0.025
L41.1 Pityriasis lichenoides chronica
0.000 0.975 0.025
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.975 0.025
L44.9 Papulosquamous disorder, unspecified
0.000 0.975 0.025
L44.8 Other specified papulosquamous disorders
0.000 0.975 0.025
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.975 0.025
L44.3 Lichen ruber moniliformis
0.000 0.975 0.025
L44.2 Lichen striatus
0.000 0.975 0.025
L44.1 Lichen nitidus
0.000 0.975 0.025
L44.0 Pityriasis rubra pilaris
0.000 0.975 0.025
E83.9 Disorder of mineral metabolism, unspecified
0.025 0.975 0.000
N48.2 Other inflammatory disorders of penis
0.000 0.975 0.025
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.975 0.024
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.976 0.024
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.024 0.976 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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