TreeWAS – Variant ID: rs2063730

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.1 Hallux valgus (acquired)	0.000	0.330	0.670
M20 Acquired deformities of fingers and toes	0.000	0.404	0.596
M20.5 Other deformities of toe(s) (acquired)	0.000	0.428	0.572
M20.4 Other hammer toe(s) (acquired)	0.000	0.443	0.557
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.529	0.471
M20.0 Deformity of finger(s)	0.000	0.597	0.403
M20.2 Hallux rigidus	0.000	0.668	0.332
M20.3 Other deformity of hallux (acquired)	0.000	0.744	0.256
N95.8 Other specified menopausal and perimenopausal disorders	0.024	0.976	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.982	0.018
E10.0 With coma	0.000	0.983	0.017
N93.8 Other specified abnormal uterine and vaginal bleeding	0.016	0.984	0.000
E10.4 With neurological complications	0.000	0.984	0.016
E10.5 With peripheral circulatory complications	0.000	0.984	0.016
E10.2 With renal complications	0.000	0.984	0.016
E10.3 With ophthalmic complications	0.000	0.984	0.016
E10.6 With other specified complications	0.000	0.985	0.015
E10.8 With unspecified complications	0.000	0.985	0.015
E10.1 With ketoacidosis	0.000	0.985	0.015
I27.2 Other secondary pulmonary hypertension	0.014	0.986	0.000
E10.9 Without complications	0.000	0.986	0.014
E10.7 With multiple complications	0.000	0.987	0.013
Z95.4 Presence of other heart-valve replacement	0.013	0.987	0.000
H53.1 Subjective visual disturbances	0.013	0.987	0.000
H21 Other disorders of iris and ciliary body	0.013	0.987	0.000
I27.0 Primary pulmonary hypertension	0.012	0.988	0.000
H21.8 Other specified disorders of iris and ciliary body	0.012	0.988	0.000
H16 Keratitis	0.012	0.988	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.012	0.988	0.000
I27 Other pulmonary heart diseases	0.012	0.988	0.000
H18 Other disorders of cornea	0.012	0.988	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.012	0.988	0.000
H16.0 Corneal ulcer	0.012	0.988	0.000
H16.9 Keratitis, unspecified	0.011	0.989	0.000
H18.9 Disorder of cornea, unspecified	0.011	0.989	0.000
H21.0 Hyphaema	0.010	0.989	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.010	0.990	0.000
H18.8 Other specified disorders of cornea	0.010	0.990	0.000
H18.2 Other corneal oedema	0.010	0.990	0.000
H16.8 Other keratitis	0.010	0.990	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.010	0.990	0.000
H18.5 Hereditary corneal dystrophies	0.010	0.990	0.000
H21.4 Pupillary membranes	0.009	0.990	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.009	0.990	0.000
H21.2 Degeneration of iris and ciliary body	0.009	0.991	0.000
Y84.2 Radiological procedure and radiotherapy	0.009	0.991	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.009	0.991	0.000
H18.6 Keratoconus	0.009	0.991	0.000
H16.4 Corneal neovascularisation	0.009	0.991	0.000
H16.3 Interstitial and deep keratitis	0.009	0.991	0.000
H18.4 Corneal degeneration	0.009	0.991	0.000
I27.9 Pulmonary heart disease, unspecified	0.009	0.991	0.000
H17 Corneal scars and opacities	0.009	0.991	0.000
I27.1 Kyphoscoliotic heart disease	0.009	0.991	0.000
H18.7 Other corneal deformities	0.009	0.991	0.000
H18.3 Changes in corneal membranes	0.009	0.991	0.000
H18.0 Corneal pigmentations and deposits	0.009	0.991	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.008	0.991	0.000
H16.2 Keratoconjunctivitis	0.008	0.992	0.000
H15 Disorders of sclera	0.008	0.992	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.992	0.008
I27.8 Other specified pulmonary heart diseases	0.008	0.992	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.007	0.993	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.007	0.993	0.000
T43.2 Other and unspecified antidepressants	0.000	0.993	0.007
H17.9 Corneal scar and opacity, unspecified	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.993	0.007
H18.1 Bullous keratopathy	0.006	0.993	0.000
H17.1 Other central corneal opacity	0.006	0.993	0.000
H17.0 Adherent leukoma	0.006	0.993	0.000
H17.8 Other corneal scars and opacities	0.006	0.993	0.000
H15.1 Episcleritis	0.006	0.994	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.006	0.994	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.994	0.006
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.994	0.006
H15.9 Disorder of sclera, unspecified	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.994	0.006
D73.0 Hyposplenism	0.006	0.994	0.000
H15.0 Scleritis	0.006	0.994	0.000
T51.0 Ethanol	0.000	0.994	0.006
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.994	0.006
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.006	0.994	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.994	0.006
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.005	0.994	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.005	0.994	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.005	0.994	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.005	0.995	0.000
H15.8 Other disorders of sclera	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
D35.0 Adrenal gland	0.000	0.995	0.005
T43.9 Psychotropic drug, unspecified	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.995	0.005
S64.4 Injury of digital nerve of other finger	0.000	0.995	0.005
B02.9 Zoster without complication	0.005	0.995	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.005	0.995	0.000
I49.5 Sick sinus syndrome	0.005	0.995	0.000
B37.3 Candidiasis of vulva and vagina	0.000	0.995	0.005
D73 Diseases of spleen	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
G43.9 Migraine, unspecified	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.995	0.005
T82.1 Mechanical complication of cardiac electronic device	0.005	0.995	0.000
I49.4 Other and unspecified premature depolarisation	0.005	0.995	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
H20 Iridocyclitis	0.004	0.996	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.996	0.004
S06.2 Diffuse brain injury	0.004	0.996	0.000
D73.3 Abscess of spleen	0.004	0.996	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.004	0.996	0.000
D35.1 Parathyroid gland	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.996	0.004
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.996	0.004
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.996	0.004
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
S06 Intracranial injury	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.000	0.996	0.004
D73.5 Infarction of spleen	0.004	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.996	0.000
D73.1 Hypersplenism	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.004
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.004
T50.5 Appetite depressants	0.000	0.996	0.004
T50.4 Drugs affecting uric acid metabolism	0.000	0.996	0.004
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.996	0.004
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.004
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.004
I49 Other cardiac arrhythmias	0.004	0.996	0.000
D35.2 Pituitary gland	0.000	0.996	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
B37 Candidiasis	0.000	0.996	0.004
I49.9 Cardiac arrhythmia, unspecified	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
D73.8 Other diseases of spleen	0.003	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.996	0.003
S06.3 Focal brain injury	0.003	0.996	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.003	0.997	0.000
T50.8 Diagnostic agents	0.000	0.997	0.003
B37.1 Pulmonary candidiasis	0.000	0.997	0.003
I73.8 Other specified peripheral vascular diseases	0.000	0.997	0.003
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
B37.4 Candidiasis of other urogenital sites	0.000	0.997	0.003
B37.2 Candidiasis of skin and nail	0.000	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.003
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.003
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.003
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.003
T45.4 Iron and its compounds	0.000	0.997	0.003
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.003
T51 Toxic effect of alcohol	0.000	0.997	0.003
T39.0 Salicylates	0.000	0.997	0.003
U80.1 Methicillin resistant agent	0.000	0.997	0.003
D35.9 Endocrine gland, unspecified	0.000	0.997	0.003
D35.8 Pluriglandular involvement	0.000	0.997	0.003
D35.7 Other specified endocrine glands	0.000	0.997	0.003
D35.6 Aortic body and other paraganglia	0.000	0.997	0.003
D35.5 Carotid body	0.000	0.997	0.003
D35.4 Pineal gland	0.000	0.997	0.003
D35.3 Craniopharyngeal duct	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.003
H60.8 Other otitis externa	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
R44.0 Auditory hallucinations	0.000	0.997	0.003
S06.0 Concussion	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.997	0.003
I49.8 Other specified cardiac arrhythmias	0.003	0.997	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
Z90.5 Acquired absence of kidney	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
I49.2 Junctional premature depolarisation	0.003	0.997	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
B37.7 Candidal septicaemia	0.000	0.997	0.003
B37.6 Candidal endocarditis	0.000	0.997	0.003
B37.5 Candidal meningitis	0.000	0.997	0.003
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
T45.5 Anticoagulants	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
I73.0 Raynaud's syndrome	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
C44.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.002	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
T51.9 Alcohol, unspecified	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
I49.0 Ventricular fibrillation and flutter	0.003	0.997	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
H60 Otitis externa	0.003	0.997	0.000
I49.1 Atrial premature depolarisation	0.003	0.997	0.000
T51.8 Other alcohols	0.000	0.997	0.003
T51.3 Fusel oil	0.000	0.997	0.003
T51.2 2-Propanol	0.000	0.997	0.003
T51.1 Methanol	0.000	0.997	0.003
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
B37.0 Candidal stomatitis	0.000	0.997	0.003
I22.8 Subsequent myocardial infarction of other sites	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.002
T47.7 Emetics	0.000	0.997	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.002
T47.5 Digestants	0.000	0.997	0.002
T47.4 Other laxatives	0.000	0.997	0.002
T47.3 Saline and osmotic laxatives	0.000	0.997	0.002
T47.2 Stimulant laxatives	0.000	0.997	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.002
T41.5 Therapeutic gases	0.000	0.997	0.002
T41.4 Anaesthetic, unspecified	0.000	0.997	0.002
T41.3 Local anaesthetics	0.000	0.997	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.002
T41.1 Intravenous anaesthetics	0.000	0.997	0.002
T41.0 Inhaled anaesthetics	0.000	0.997	0.002
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.002
T48.5 Anti-common-cold drugs	0.000	0.997	0.002
T48.4 Expectorants	0.000	0.997	0.002
T48.3 Antitussives	0.000	0.997	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.002
T48.0 Oxytocic drugs	0.000	0.997	0.002
T49.9 Topical agent, unspecified	0.000	0.997	0.002
T49.8 Other topical agents	0.000	0.997	0.002
T49.7 Dental drugs, topically applied	0.000	0.997	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.002
T49.2 Local astringents and local detergents	0.000	0.997	0.002
T49.1 Antipruritics	0.000	0.997	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
C50.8 Overlapping lesion of breast	0.000	0.997	0.003
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.997	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.997	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.997	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.997	0.000
H20.8 Other iridocyclitis	0.002	0.997	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.003	0.997	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.002	0.997	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.002
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
R06.2 Wheezing	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
N95 Menopausal and other perimenopausal disorders	0.002	0.998	0.000
S42.1 Fracture of scapula	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
E10-E14 Diabetes mellitus	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.000	0.998	0.002
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.000	0.998	0.002
K04.8 Radicular cyst	0.000	0.998	0.002
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
S27.3 Other injuries of lung	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
D70 Agranulocytosis	0.002	0.998	0.000
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
I22 Subsequent myocardial infarction	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
N95.1 Menopausal and female climacteric states	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
S52.70 Multiple fractures of forearm (closed)	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.998	0.002
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
E13.9 Without complications	0.000	0.998	0.002
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
E13.8 With unspecified complications	0.000	0.998	0.002
E13.7 With multiple complications	0.000	0.998	0.002
E13.6 With other specified complications	0.000	0.998	0.002
E13.5 With peripheral circulatory complications	0.000	0.998	0.002
E13.4 With neurological complications	0.000	0.998	0.002
E13.3 With ophthalmic complications	0.000	0.998	0.002
E13.2 With renal complications	0.000	0.998	0.002
E13.1 With ketoacidosis	0.000	0.998	0.002
E13.0 With coma	0.000	0.998	0.002
D12.7 Rectosigmoid junction	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
E12.9 Without complications	0.000	0.998	0.001
E12.8 With unspecified complications	0.000	0.998	0.001
E12.7 With multiple complications	0.000	0.998	0.001
E12.6 With other specified complications	0.000	0.998	0.001
E12.5 With peripheral circulatory complications	0.000	0.998	0.001
E12.4 With neurological complications	0.000	0.998	0.001
E12.3 With ophthalmic complications	0.000	0.998	0.001
E12.2 With renal complications	0.000	0.998	0.001
E12.1 With ketoacidosis	0.000	0.998	0.001
E12.0 With coma	0.000	0.998	0.001
S27.2 Traumatic heamopneumothorax	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.001
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
L50.8 Other urticaria	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.001	0.998	0.000
D74.8 Other methaemoglobinaemias	0.001	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.001	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.001	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.002	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.998	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.001
B02 Zoster [herpes zoster]	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.998	0.000
R44.1 Visual hallucinations	0.000	0.998	0.002
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.001
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.001
M19.0 Primary arthrosis of other joints	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.002	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.000	0.998	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.001
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.001
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.001
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.001
M25.83 Other specified joint disorders (Forearm)	0.000	0.998	0.001
C34.3 Lower lobe, bronchus or lung	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
H52.1 Myopia	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.001
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations