TreeWAS – Variant ID: rs206776

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E10.3 With ophthalmic complications	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
E10.1 With ketoacidosis	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
E03 Other hypothyroidism	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.002	0.998
J33.9 Nasal polyp, unspecified	0.000	0.002	0.998
E03.9 Hypothyroidism, unspecified	0.000	0.003	0.997
J33 Nasal polyp	0.000	0.003	0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.003	0.997
T36-T50 Poisoning by drugs, medicaments and biological substances	0.996	0.004	0.000
L40.5 Arthropathic psoriasis	0.996	0.004	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.995	0.005	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.006	0.994
L40 Psoriasis	0.993	0.007	0.000
J33.0 Polyp of nasal cavity	0.000	0.008	0.992
L40.9 Psoriasis, unspecified	0.991	0.009	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.991	0.009	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.988	0.012	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.013	0.987
J45.9 Asthma, unspecified	0.000	0.014	0.986
J33.8 Other polyp of sinus	0.000	0.016	0.984
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.978	0.022	0.000
E10.4 With neurological complications	0.000	0.024	0.976
M06 Other rheumatoid arthritis	0.000	0.028	0.972
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.035	0.965
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.037	0.963
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.962	0.038	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.962	0.038	0.000
M06.0 Seronegative rheumatoid arthritis	0.000	0.044	0.956
E40-E46 Malnutrition	0.000	0.048	0.952
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.055	0.945
L40.8 Other psoriasis	0.941	0.059	0.000
T42.4 Benzodiazepines	0.941	0.059	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.933	0.067	0.000
T43.2 Other and unspecified antidepressants	0.928	0.072	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.078	0.922
E46 Unspecified protein-energy malnutrition	0.000	0.083	0.917
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.083	0.917
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.088	0.912
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.108	0.892
T39.1 4-Aminophenol derivatives	0.882	0.118	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.876	0.124	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.127	0.873
K90 Intestinal malabsorption	0.000	0.134	0.866
E10.8 With unspecified complications	0.000	0.137	0.863
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.856	0.144	0.000
E13 Other specified diabetes mellitus	0.000	0.147	0.853
E16.1 Other hypoglycaemia	0.000	0.152	0.848
K90.9 Intestinal malabsorption, unspecified	0.000	0.162	0.838
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.837	0.163	0.000
E07 Other disorders of thyroid	0.000	0.167	0.833
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.180	0.820
T42.1 Iminostilbenes	0.814	0.186	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.813	0.187	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.788	0.212	0.000
G35 Multiple sclerosis	0.785	0.215	0.000
E10.6 With other specified complications	0.000	0.216	0.784
T50.1 Loop [high-ceiling] diuretics	0.778	0.222	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.772	0.228	0.000
E13.9 Without complications	0.000	0.234	0.766
T36 Poisoning by systemic antibiotics	0.765	0.235	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.235	0.764
E05.8 Other thyrotoxicosis	0.000	0.238	0.762
E10.2 With renal complications	0.000	0.239	0.761
T50.8 Diagnostic agents	0.761	0.239	0.000
T42.0 Hydantoin derivatives	0.759	0.241	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.758	0.242	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.758	0.242	0.000
T39.0 Salicylates	0.757	0.243	0.000
E10.5 With peripheral circulatory complications	0.000	0.246	0.754
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.751	0.249	0.000
M06.3 Rheumatoid nodule	0.000	0.255	0.745
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.744	0.256	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.743	0.257	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.259	0.741
E07.9 Disorder of thyroid, unspecified	0.000	0.266	0.734
M06.4 Inflammatory polyarthropathy	0.000	0.268	0.732
E03.8 Other specified hypothyroidism	0.000	0.268	0.732
E03.1 Congenital hypothyroidism without goitre	0.000	0.268	0.731
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.281	0.719
T43.6 Psychostimulants with abuse potential	0.718	0.281	0.000
E10.7 With multiple complications	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E15 Nondiabetic hypoglycaemic coma	0.000	0.285	0.714
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.714	0.286	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.714	0.286	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.713	0.287	0.000
T42.3 Barbiturates	0.713	0.287	0.000
T42.2 Succinimides and oxazolidinediones	0.713	0.287	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.287	0.713
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.287	0.713
E16.4 Abnormal secretion of gastrin	0.000	0.287	0.713
E16.3 Increased secretion of glucagon	0.000	0.287	0.713
L40.4 Guttate psoriasis	0.712	0.288	0.000
L40.2 Acrodermatitis continua	0.712	0.288	0.000
T43.9 Psychotropic drug, unspecified	0.710	0.289	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.710	0.289	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.710	0.289	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.709	0.291	0.000
T39.4 Antirheumatics, not elsewhere classified	0.708	0.292	0.000
T39.2 Pyrazolone derivatives	0.708	0.292	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.296	0.704
T38.1 Thyroid hormones and substitutes	0.698	0.302	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.697	0.303	0.000
M06.2 Rheumatoid bursitis	0.000	0.303	0.697
M06.1 Adult-onset Still's disease	0.000	0.303	0.697
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.686	0.314	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.314	0.685
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.314	0.685
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.314	0.685
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.314	0.685
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.314	0.685
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.318	0.682
E45 Retarded development following protein-energy malnutrition	0.000	0.318	0.682
E43 Unspecified severe protein-energy malnutrition	0.000	0.318	0.682
E42 Marasmic kwashiorkor	0.000	0.318	0.682
E41 Nutritional marasmus	0.000	0.318	0.682
E40 Kwashiorkor	0.000	0.318	0.682
L40.3 Pustulosis palmaris et plantaris	0.682	0.318	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.318	0.682
J33.1 Polypoid sinus degeneration	0.000	0.321	0.679
T50.7 Analeptics and opioid receptor antagonists	0.669	0.331	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.669	0.331	0.000
T50.5 Appetite depressants	0.669	0.331	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.669	0.331	0.000
T50.0 Mineralocorticoids and their antagonists	0.669	0.331	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.334	0.666
L40.1 Generalised pustular psoriasis	0.664	0.336	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.347	0.653
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.356	0.644
L40.0 Psoriasis vulgaris	0.642	0.358	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.359	0.641
E10.0 With coma	0.000	0.363	0.637
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.635	0.365	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.366	0.633
T50.4 Drugs affecting uric acid metabolism	0.633	0.367	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.633	0.367	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.379	0.621
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.379	0.621
K90.1 Tropical sprue	0.000	0.379	0.621
T38.9 Other and unspecified hormone antagonists	0.613	0.386	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.613	0.386	0.000
T38.7 Androgens and anabolic congeners	0.613	0.386	0.000
T38.5 Other oestrogens and progestogens	0.613	0.386	0.000
T38.4 Oral contraceptives	0.613	0.386	0.000
T38.2 Antithyroid drugs	0.613	0.386	0.000
T38.0 Glucocorticoids and synthetic analogues	0.613	0.386	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.387	0.613
T47.2 Stimulant laxatives	0.613	0.387	0.000
E13.8 With unspecified complications	0.000	0.388	0.612
E13.7 With multiple complications	0.000	0.388	0.612
E13.6 With other specified complications	0.000	0.388	0.612
E13.5 With peripheral circulatory complications	0.000	0.388	0.612
E13.4 With neurological complications	0.000	0.388	0.612
E13.2 With renal complications	0.000	0.388	0.612
E13.1 With ketoacidosis	0.000	0.388	0.612
E13.0 With coma	0.000	0.388	0.612
M06.34 Rheumatoid nodule (Hand)	0.000	0.389	0.610
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.392	0.608
T36.3 Macrolides	0.602	0.398	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.601	0.399	0.000
E07.1 Dyshormogenetic goitre	0.000	0.402	0.598
E07.0 Hypersecretion of calcitonin	0.000	0.402	0.598
K90.8 Other intestinal malabsorption	0.000	0.418	0.582
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.431	0.569
T47.0 Histamine H(2)-receptor antagonists	0.563	0.437	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.561	0.439	0.000
E13.3 With ophthalmic complications	0.000	0.439	0.561
T47.4 Other laxatives	0.555	0.445	0.000
M05-M14 Inflammatory polyarthropathies	0.004	0.448	0.548
E07.8 Other specified disorders of thyroid	0.000	0.448	0.552
T36.9 Systemic antibiotic, unspecified	0.549	0.451	0.000
T36.8 Other systemic antibiotics	0.549	0.451	0.000
T36.7 Antifungal antibiotics, systemically used	0.549	0.451	0.000
T36.6 Rifamycins	0.549	0.451	0.000
T36.5 Aminoglycosides	0.549	0.451	0.000
T36.4 Tetracyclines	0.549	0.451	0.000
T36.2 Chloramphenicol group	0.549	0.451	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.549	0.451	0.000
T36.0 Penicillins	0.547	0.453	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.454	0.544
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.455	0.544
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.456	0.544
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.543	0.456	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.543	0.456	0.000
T47.7 Emetics	0.543	0.456	0.000
T47.6 Antidiarrhoeal drugs	0.543	0.456	0.000
T47.5 Digestants	0.543	0.456	0.000
T47.3 Saline and osmotic laxatives	0.543	0.456	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.458	0.542
T46.3 Coronary vasodilators, not elsewhere classified	0.539	0.461	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.535	0.465	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.466	0.534
M06.38 Rheumatoid nodule (Other)	0.000	0.466	0.534
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.466	0.534
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.466	0.534
M06.33 Rheumatoid nodule (Forearm)	0.000	0.466	0.534
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.466	0.534
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.532	0.467	0.000
T37.5 Antiviral drugs	0.532	0.467	0.000
T37.4 Anthelminthics	0.532	0.467	0.000
T37.3 Other antiprotozoal drugs	0.532	0.467	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.532	0.467	0.000
T37.1 Antimycobacterial drugs	0.532	0.467	0.000
T37.0 Sulphonamides	0.532	0.467	0.000
J45 Asthma	0.000	0.472	0.528
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.475	0.525
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.475	0.525
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.475	0.525
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.475	0.525
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.475	0.525
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.475	0.525
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.475	0.525
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.475	0.525
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.477	0.523
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.485	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
T41.5 Therapeutic gases	0.512	0.488	0.000
T41.4 Anaesthetic, unspecified	0.512	0.488	0.000
T41.3 Local anaesthetics	0.512	0.488	0.000
T41.2 Other and unspecified general anaesthetics	0.512	0.488	0.000
T41.1 Intravenous anaesthetics	0.512	0.488	0.000
T41.0 Inhaled anaesthetics	0.512	0.488	0.000
T49.9 Topical agent, unspecified	0.512	0.488	0.000
T49.8 Other topical agents	0.512	0.488	0.000
T49.7 Dental drugs, topically applied	0.512	0.488	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.512	0.488	0.000
T49.5 Ophthalmological drugs and preparations	0.512	0.488	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.512	0.488	0.000
T49.3 Emollients, demulcents and protectants	0.512	0.488	0.000
T49.2 Local astringents and local detergents	0.512	0.488	0.000
T49.1 Antipruritics	0.512	0.488	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.512	0.488	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.509	0.491	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.502	0.498	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.500	0.500	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.500	0.500	0.000
T46.7 Peripheral vasodilators	0.500	0.500	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.500	0.500	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.500	0.500	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.500	0.500
M06.18 Adult-onset Still's disease (Other)	0.000	0.500	0.500
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.500	0.500
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.500	0.500
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.500	0.500
M06.14 Adult-onset Still's disease (Hand)	0.000	0.500	0.500
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.500	0.500
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.500	0.500
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.500	0.500
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.500	0.500
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.500	0.500
M06.28 Rheumatoid bursitis (Other)	0.000	0.500	0.500
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.500	0.500
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.500	0.500
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.500	0.500
M06.24 Rheumatoid bursitis (Hand)	0.000	0.500	0.500
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.500	0.500
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.500	0.500
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.500	0.500
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.500	0.500
T45.1 Antineoplastic and immunosuppressive drugs	0.496	0.504	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.508	0.492
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.492	0.508	0.000
T48.5 Anti-common-cold drugs	0.492	0.508	0.000
T48.4 Expectorants	0.492	0.508	0.000
T48.3 Antitussives	0.492	0.508	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.492	0.508	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.492	0.508	0.000
T48.0 Oxytocic drugs	0.492	0.508	0.000
E06 Thyroiditis	0.000	0.509	0.491
E14 Unspecified diabetes mellitus	0.000	0.509	0.491
E44.1 Mild protein-energy malnutrition	0.000	0.511	0.489
E44.0 Moderate protein-energy malnutrition	0.000	0.511	0.489
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.512	0.488
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.481	0.519	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.522	0.478
T45.0 Antiallergic and antiemetic drugs	0.477	0.523	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.532	0.468
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.532	0.468
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.532	0.468
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.532	0.468
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.532	0.468
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.532	0.468
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.532	0.468
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.532	0.468
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.532	0.468
T46.4 Angiotensin-converting-enzyme inhibitors	0.465	0.534	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.465	0.535	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.463	0.537	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.543	0.456
T45.9 Primarily systemic and haematological agent, unspecified	0.455	0.545	0.000
T45.8 Other primarily systemic and haematological agents	0.455	0.545	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.455	0.545	0.000
T45.6 Fibrinolysis-affecting drugs	0.455	0.545	0.000
T45.4 Iron and its compounds	0.455	0.545	0.000
T45.3 Enzymes, not elsewhere classified	0.455	0.545	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.454	0.546	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.454	0.546	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.454	0.546	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.454	0.546	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.454	0.546	0.000
T44.0 Anticholinesterase agents	0.454	0.546	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.448	0.552	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.576	0.424
T46.1 Calcium-channel blockers	0.418	0.581	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.592	0.408
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.592	0.408
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.405	0.595	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.596	0.404
J45.1 Nonallergic asthma	0.000	0.598	0.402
M09 Juvenile arthritis in diseases classified elsewhere	0.003	0.604	0.393
M08 Juvenile arthritis	0.003	0.604	0.393
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.002	0.609	0.390
M05.1 Rheumatoid lung disease	0.002	0.609	0.390
M05.0 Felty's syndrome	0.002	0.609	0.390
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.609	0.390
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.609	0.390
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.609	0.390
M11 Other crystal arthropathies	0.003	0.611	0.386
J40-J47 Chronic lower respiratory diseases	0.000	0.614	0.386
E14.3 With ophthalmic complications	0.000	0.622	0.378
T45.2 Vitamins, not elsewhere classified	0.375	0.624	0.000
M05.2 Rheumatoid vasculitis	0.002	0.629	0.369
M05.8 Other seropositive rheumatoid arthritis	0.002	0.630	0.368
T45.5 Anticoagulants	0.370	0.630	0.000
E04 Other non-toxic goitre	0.000	0.634	0.366
T43.0 Tricyclic and tetracyclic antidepressants	0.365	0.635	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.636	0.363
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.639	0.360
E14.4 With neurological complications	0.000	0.641	0.359
E14.2 Withrenal complications	0.000	0.644	0.356
J46 Status asthmaticus	0.000	0.645	0.355
J45.8 Mixed asthma	0.000	0.646	0.354
E06.4 Drug-induced thyroiditis	0.000	0.648	0.352
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.648	0.352
E06.1 Subacute thyroiditis	0.000	0.648	0.352
E06.0 Acute thyroiditis	0.000	0.648	0.352
E14.7 With multiple complications	0.000	0.648	0.352
E14.0 With coma	0.000	0.648	0.352
E14.6 With other specified complications	0.000	0.649	0.350
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.652	0.348
E06.3 Autoimmune thyroiditis	0.000	0.654	0.346
E14.1 With ketoacidosis	0.000	0.661	0.339
E14.8 With unspecified complications	0.000	0.661	0.339
J47 Bronchiectasis	0.000	0.662	0.338
M07 Psoriatic and enteropathic arthropathies	0.098	0.668	0.234
E50-E64 Other nutritional deficiencies	0.000	0.669	0.330
E14.5 With peripheral circulatory complications	0.000	0.672	0.327
G35-G37 Demyelinating diseases of the central nervous system	0.324	0.676	0.000
M12 Other specific arthropathies	0.004	0.681	0.315
T40.1 Heroin	0.315	0.684	0.000
E06.5 Other chronic thyroiditis	0.000	0.685	0.315
M14 Arthropathies in other diseases classified elsewhere	0.004	0.695	0.302
M10 Gout	0.002	0.703	0.296
M11.2 Other chondrocalcinosis	0.001	0.703	0.296
T40.5 Cocaine	0.294	0.706	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.291	0.709	0.000
T40.8 Lysergide [LSD]	0.291	0.709	0.000
T40.7 Cannabis (derivatives)	0.291	0.709	0.000
T40.3 Methadone	0.291	0.709	0.000
T40.0 Opium	0.291	0.709	0.000
E67 Other hyperalimentation	0.000	0.710	0.290
E68 Sequelae of hyperalimentation	0.000	0.710	0.290
J42 Unspecified chronic bronchitis	0.000	0.715	0.285
M08.9 Juvenile arthritis, unspecified	0.002	0.716	0.282
M08.8 Other juvenile arthritis	0.002	0.716	0.282
M08.4 Pauciarticular juvenile arthritis	0.002	0.716	0.282
M08.3 Juvenile polyarthritis (seronegative)	0.002	0.716	0.282
M08.2 Juvenile arthritis with systemic onset	0.002	0.716	0.282
M08.1 Juvenile ankylosing spondylitis	0.002	0.716	0.282
M08.0 Juvenile rheumatoid arthritis	0.002	0.716	0.282
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.002	0.716	0.282
M09.2 Juvenile arthritis in ulcerative colitis	0.002	0.716	0.282
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.002	0.716	0.282
M09.0 Juvenile arthritis in psoriasis	0.002	0.716	0.282
E04.1 Non-toxic single thyroid nodule	0.000	0.717	0.283
M05.09 Felty's syndrome (Site unspecified)	0.001	0.719	0.279
M05.08 Felty's syndrome (Other)	0.001	0.719	0.279
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.719	0.279
M05.06 Felty's syndrome (Lower leg)	0.001	0.719	0.279
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.719	0.279
M05.04 Felty's syndrome (Hand)	0.001	0.719	0.279
M05.03 Felty's syndrome (Forearm)	0.001	0.719	0.279
M05.02 Felty's syndrome (Upper arm)	0.001	0.719	0.279
M05.01 Felty's syndrome (Shoulder region)	0.001	0.719	0.279
M05.00 Felty's syndrome (Multiple sites)	0.001	0.719	0.279
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.719	0.279
M05.18 Rheumatoid lung disease (Other)	0.001	0.719	0.279
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.719	0.279
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.719	0.279
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.719	0.279
M05.14 Rheumatoid lung disease (Hand)	0.001	0.719	0.279
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.719	0.279
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.719	0.279
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.719	0.279
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.719	0.279
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.719	0.279
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.719	0.279
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.719	0.279
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.719	0.279
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.719	0.279
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.719	0.279
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.719	0.279
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.719	0.279
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.719	0.279
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.719	0.279
M11.9 Crystal arthropathy, unspecified	0.002	0.721	0.277
M11.1 Familial chondrocalcinosis	0.002	0.721	0.277
M11.0 Hydroxyapatite deposition disease	0.002	0.721	0.277
J43 Emphysema	0.000	0.722	0.278
J40 Bronchitis, not specified as acute or chronic	0.000	0.730	0.270
T40.6 Other and unspecified narcotics	0.270	0.730	0.000
E65 Localised adiposity	0.000	0.730	0.269
J30-J39 Other diseases of upper respiratory tract	0.000	0.734	0.266
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.734	0.265
M05.28 Rheumatoid vasculitis (Other)	0.001	0.734	0.265
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.734	0.265
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.734	0.265
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.734	0.265
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.734	0.265
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.734	0.265
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.734	0.265
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.734	0.265
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.734	0.264
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.734	0.264
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.734	0.264
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.734	0.264
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.734	0.264
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.734	0.264
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.734	0.264
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.734	0.264
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.001	0.735	0.264
E04.8 Other specified non-toxic goitre	0.000	0.737	0.263
K51.9 Ulcerative colitis, unspecified	0.257	0.743	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.744	0.256
K51 Ulcerative colitis	0.253	0.747	0.000
E58 Dietary calcium deficiency	0.000	0.747	0.253
J35.1 Hypertrophy of tonsils	0.000	0.748	0.252
J35 Chronic diseases of tonsils and adenoids	0.000	0.750	0.250
M11.8 Other specified crystal arthropathies	0.002	0.751	0.247
K51.3 Ulcerative (chronic) rectosigmoiditis	0.248	0.752	0.000
M13 Other arthritis	0.001	0.754	0.245
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.755	0.244
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.755	0.243
J37 Chronic laryngitis and laryngotracheitis	0.000	0.761	0.239
M07.6 Other enteropathic arthropathies	0.070	0.762	0.168
M07.5 Arthropathy in ulcerative colitis	0.070	0.762	0.168
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.070	0.762	0.168
M07.2 Psoriatic spondylitis	0.070	0.762	0.168
M07.1 Arthritis mutilans	0.070	0.762	0.168
M07.0 Distal interphalangeal psoriatic arthropathy	0.070	0.762	0.168
M07.3 Other psoriatic arthropathies	0.228	0.762	0.010
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.763	0.237
E63 Other nutritional deficiencies	0.000	0.763	0.237
E56 Other vitamin deficiencies	0.000	0.763	0.237
E50 Vitamin A deficiency	0.000	0.763	0.237
E60 Dietary zinc deficiency	0.000	0.763	0.237
E59 Dietary selenium deficiency	0.000	0.763	0.237
E54 Ascorbic acid deficiency	0.000	0.763	0.237
E52 Niacin deficiency [pellagra]	0.000	0.763	0.237
K51.2 Ulcerative (chronic) proctitis	0.237	0.763	0.000
K51.8 Other ulcerative colitis	0.234	0.766	0.000
G36 Other acute disseminated demyelination	0.233	0.767	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.769	0.231
J43.2 Centrilobular emphysema	0.000	0.769	0.231
G37 Other demyelinating diseases of central nervous system	0.230	0.769	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations