TreeWAS – Variant ID: rs2071403

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.997	0.003	0.000
E03 Other hypothyroidism	0.500	0.500	0.000
E03.1 Congenital hypothyroidism without goitre	0.403	0.597	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.398	0.602	0.000
E03.5 Myxoedema coma	0.358	0.642	0.000
E03.4 Atrophy of thyroid (acquired)	0.358	0.642	0.000
E03.3 Postinfectious hypothyroidism	0.358	0.642	0.000
E03.8 Other specified hypothyroidism	0.335	0.665	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.320	0.680	0.000
Z45.2 Adjustment and management of vascular access device	0.000	0.963	0.037
N32.0 Bladder-neck obstruction	0.000	0.967	0.033
Z36.8 Other antenatal screening	0.000	0.973	0.027
Z45.8 Adjustment and management of other implanted devices	0.000	0.981	0.019
Z45 Adjustment and management of implanted device	0.000	0.981	0.019
R44.3 Hallucinations, unspecified	0.000	0.982	0.018
E23.0 Hypopituitarism	0.000	0.984	0.016
N13 Obstructive and reflux uropathy	0.000	0.984	0.016
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.985	0.015
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.985	0.015
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.985	0.015
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.985	0.015
Z45.3 Adjustment and management of implanted hearing device	0.000	0.986	0.014
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.986	0.014
N13.6 Pyonephrosis	0.000	0.987	0.013
N13.3 Other and unspecified hydronephrosis	0.000	0.987	0.013
C54.1 Endometrium	0.013	0.987	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.988	0.012
G25.3 Myoclonus	0.000	0.989	0.011
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.989	0.011
E00-E07 Disorders of thyroid gland	0.011	0.989	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.990	0.010
G25 Other extrapyramidal and movement disorders	0.000	0.990	0.010
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.990	0.010
N13.4 Hydroureter	0.000	0.991	0.009
Z36 Antenatal screening	0.000	0.991	0.009
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.991	0.009
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.991	0.009
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.992	0.008
C54 Malignant neoplasm of corpus uteri	0.008	0.992	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.992	0.008
N11 Chronic tubulo-interstitial nephritis	0.000	0.992	0.008
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.992	0.008
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.992	0.008
Y42.5 Other oestrogens and progestogens	0.000	0.992	0.008
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.008	0.992	0.000
E00 Congenital iodine-deficiency syndrome	0.008	0.992	0.000
G25.2 Other specified forms of tremor	0.000	0.992	0.008
G25.5 Other chorea	0.000	0.992	0.008
E02 Subclinical iodine-deficiency hypothyroidism	0.008	0.992	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.008	0.992	0.000
G25.0 Essential tremor	0.000	0.992	0.008
N32.1 Vesicointestinal fistula	0.000	0.992	0.008
C54.9 Corpus uteri, unspecified	0.008	0.992	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.008	0.992	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.993	0.007
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.993	0.007
G25.4 Drug-induced chorea	0.000	0.993	0.007
N10-N16 Renal tubulo-interstitial diseases	0.000	0.993	0.007
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.993	0.007
R44.2 Other hallucinations	0.000	0.993	0.007
N11.1 Chronic obstructive pyelonephritis	0.000	0.993	0.007
N32 Other disorders of bladder	0.000	0.993	0.007
C83.3 Large cell (diffuse)	0.000	0.993	0.007
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.007	0.993	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.993	0.007
Z36.5 Antenatal screening for isoimmunisation	0.000	0.993	0.006
N99.0 Postprocedural renal failure	0.006	0.994	0.000
G25.1 Drug-induced tremor	0.000	0.994	0.006
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.994	0.006
C32.9 Larynx, unspecified	0.000	0.994	0.006
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.994	0.006
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.994	0.006
C54.8 Overlapping lesion of corpus uteri	0.006	0.994	0.000
C54.3 Fundus uteri	0.006	0.994	0.000
C54.2 Myometrium	0.006	0.994	0.000
C54.0 Isthmus uteri	0.006	0.994	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.994	0.006
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.006	0.994	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.006	0.994	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.006	0.994	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.006	0.994	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.006	0.994	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.006	0.994	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.006	0.994	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.006	0.994	0.000
J33.8 Other polyp of sinus	0.006	0.994	0.000
R44.0 Auditory hallucinations	0.000	0.994	0.006
E06 Thyroiditis	0.006	0.994	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.994	0.006
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.994	0.006
S42.40 Fracture of lower end of humerus (closed)	0.000	0.994	0.006
K86.8 Other specified diseases of pancreas	0.000	0.994	0.006
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.994	0.005
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.994	0.006
R44.1 Visual hallucinations	0.000	0.995	0.005
E23 Hypofunction and other disorders of pituitary gland	0.000	0.995	0.005
M89.9 Disorder of bone, unspecified	0.000	0.995	0.005
E06.1 Subacute thyroiditis	0.005	0.995	0.000
N32.4 Rupture of bladder, nontraumatic	0.000	0.995	0.005
N99.1 Postprocedural urethral stricture	0.005	0.995	0.000
C32.0 Glottis	0.000	0.995	0.005
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.005	0.995	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.995	0.005
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.995	0.005
N15 Other renal tubulo-interstitial diseases	0.000	0.995	0.005
O20 Haemorrhage in early pregnancy	0.000	0.995	0.005
E23.2 Diabetes insipidus	0.000	0.995	0.005
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.995	0.005
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.995	0.005
E07 Other disorders of thyroid	0.005	0.995	0.000
C32 Malignant neoplasm of larynx	0.000	0.995	0.005
N32.2 Vesical fistula, not elsewhere classified	0.000	0.995	0.005
F30.0 Hypomania	0.000	0.995	0.005
E06.4 Drug-induced thyroiditis	0.004	0.995	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.004	0.995	0.000
E06.0 Acute thyroiditis	0.004	0.995	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.995	0.004
N14.3 Nephropathy induced by heavy metals	0.000	0.995	0.004
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.995	0.004
N14.0 Analgesic nephropathy	0.000	0.995	0.004
O20.0 Threatened abortion	0.000	0.995	0.005
M25.71 Osteophyte (Shoulder region)	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.996	0.004
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.996	0.004
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.996	0.004
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.996	0.004
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.996	0.004
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.996	0.004
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.996	0.004
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
M31.6 Other giant cell arteritis	0.004	0.996	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.996	0.004
N99.2 Postprocedural adhesions of vagina	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.996	0.004
E23.1 Drug-induced hypopituitarism	0.000	0.996	0.004
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.996	0.004
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.996	0.004
E06.5 Other chronic thyroiditis	0.004	0.996	0.000
E06.9 Thyroiditis, unspecified	0.004	0.996	0.000
N99.5 Malfunction of external stoma of urinary tract	0.004	0.996	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.996	0.004
J18.0 Bronchopneumonia, unspecified	0.000	0.996	0.004
G82.2 Paraplegia, unspecified	0.000	0.996	0.004
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.996	0.004
N15.0 Balkan nephropathy	0.000	0.996	0.004
E07.1 Dyshormogenetic goitre	0.003	0.996	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.996	0.000
C32.8 Overlapping lesion of larynx	0.000	0.996	0.004
C32.3 Laryngeal cartilage	0.000	0.996	0.004
N10 Acute tubulo-interstitial nephritis	0.000	0.996	0.004
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.996	0.004
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.996	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.996	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
C32.2 Subglottis	0.000	0.996	0.003
C32.1 Supraglottis	0.000	0.997	0.003
N15.1 Renal and perinephric abscess	0.000	0.997	0.003
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.000	0.997	0.003
M89.98 Disorder of bone, unspecified (Other)	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
S65.5 Injury of blood vessel(s) of other finger	0.000	0.997	0.003
Z36.9 Antenatal screening, unspecified	0.000	0.997	0.003
M54.64 Pain in thoracic spine (Thoracic region)	0.003	0.997	0.000
O20.8 Other haemorrhage in early pregnancy	0.000	0.997	0.003
F30 Manic episode	0.000	0.997	0.003
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.000	0.997	0.003
S62.60 Fracture of other finger (closed)	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
F30.2 Mania with psychotic symptoms	0.000	0.997	0.003
Z09.2 Follow-up examination after chemotherapy for other conditions	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
K86 Other diseases of pancreas	0.000	0.997	0.003
C90.0 Multiple myeloma	0.000	0.997	0.003
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
N99-N99 Other disorders of the genitourinary system	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
N32.3 Diverticulum of bladder	0.000	0.997	0.003
K82.1 Hydrops of gallbladder	0.000	0.997	0.003
H83.0 Labyrinthitis	0.000	0.997	0.003
G82.4 Spastic tetraplegia	0.000	0.997	0.003
G82 Paraplegia and tetraplegia	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
F30.8 Other manic episodes	0.000	0.997	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.997	0.000
F30.1 Mania without psychotic symptoms	0.000	0.997	0.002
M24.1 Other articular cartilage disorders	0.003	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
S65 Injury of blood vessels at wrist and hand level	0.000	0.998	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
S62.6 Fracture of other finger	0.000	0.998	0.002
Y84.1 Kidney dialysis	0.000	0.998	0.002
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.998	0.002
S62.61 Fracture of other finger (open)	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
C25.0 Head of pancreas	0.000	0.998	0.002
S65.1 Injury of radial artery at wrist and hand level	0.000	0.998	0.002
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.998	0.002
S65.4 Injury of blood vessel(s) of thumb	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
O21 Excessive vomiting in pregnancy	0.000	0.998	0.002
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.998	0.002
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.998	0.002
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.998	0.002
S65.3 Injury of deep palmar arch	0.000	0.998	0.002
S65.2 Injury of superficial palmar arch	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.998	0.002
S56.7 Injury of multiple muscles and tendons at forearm level	0.000	0.998	0.002
S56 Injury of muscle and tendon at forearm level	0.000	0.998	0.002
O21.2 Late vomiting of pregnancy	0.000	0.998	0.002
N32.9 Bladder disorder, unspecified	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
K02.8 Other dental caries	0.000	0.998	0.002
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.002
M24.0 Loose body in joint	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.000	0.998	0.002
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
W06.0 Home	0.000	0.998	0.002
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
W06.9 Unspecified place	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.998	0.001
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.998	0.002
S56.2 Injury of other flexor muscle and tendon at forearm level	0.000	0.998	0.002
S56.5 Injury of other extensor muscle and tendon at forearm level	0.000	0.998	0.002
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
Y40.0 Penicillins	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
M24.03 Loose body in joint (Forearm)	0.002	0.998	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.002	0.998	0.000
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.000	0.998	0.002
M35.7 Hypermobility syndrome	0.000	0.998	0.002
M24.09 Loose body in joint (Site unspecified)	0.001	0.998	0.000
M24.08 Loose body in joint (Other)	0.001	0.998	0.000
M24.00 Loose body in joint (Multiple sites)	0.001	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.998	0.002
R06.8 Other and unspecified abnormalities of breathing	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.998	0.000
M24.58 Contracture of joint (Other)	0.001	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.001	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.001	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
S42 Fracture of shoulder and upper arm	0.000	0.998	0.002
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.001	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.001	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.001	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.001	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.001	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.001	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.001	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.001	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.001	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
Z51.4 Preparatory care for treatment, not elsewhere classified	0.000	0.998	0.002
M94.88 Other specified disorders of cartilage (Other)	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.001
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.000	0.998	0.001
X51.9 Unspecified place	0.002	0.998	0.000
C56 Malignant neoplasm of ovary	0.002	0.998	0.000
K36 Other appendicitis	0.000	0.998	0.002
M24 Other specific joint derangements	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.001
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.001
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.001
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.001
Z32.1 Pregnancy confirmed	0.000	0.998	0.002
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.001
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.000	0.998	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.001
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.998	0.002
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.001	0.998	0.001
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.001	0.998	0.001
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.001	0.998	0.001
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.001
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.001	0.998	0.001
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.001	0.998	0.001
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.001	0.998	0.001
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.001	0.998	0.001
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.001	0.998	0.001
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.001
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.000	0.998	0.001
C25.3 Pancreatic duct	0.000	0.998	0.001
M31.1 Thrombotic microangiopathy	0.001	0.998	0.000
K37 Unspecified appendicitis	0.000	0.998	0.002
M24.06 Loose body in joint-Lower leg	0.001	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.001	0.998	0.000
C25.7 Other parts of pancreas	0.000	0.999	0.001
E07.9 Disorder of thyroid, unspecified	0.001	0.999	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.001	0.999	0.000
M31.2 Lethal midline granuloma	0.001	0.999	0.000
Q55 Other congenital malformations of male genital organs	0.001	0.999	0.000
M24.9 Joint derangement, unspecified	0.001	0.999	0.000
M24.6 Ankylosis of joint	0.001	0.999	0.000
C58 Malignant neoplasm of placenta	0.001	0.999	0.000
C25.1 Body of pancreas	0.000	0.999	0.001
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.999	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.999	0.001
M24.7 Protrusio acetabuli	0.001	0.999	0.000
M31.9 Necrotising vasculopathy, unspecified	0.001	0.999	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.001	0.999	0.000
Z89.5 Acquired absence of leg at or below knee	0.001	0.999	0.000
C25 Malignant neoplasm of pancreas	0.000	0.999	0.001
G96 Other disorders of central nervous system	0.001	0.999	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.999	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.999	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.999	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.999	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.999	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
H05.8 Other disorders of orbit	0.001	0.999	0.000
J39.2 Other diseases of pharynx	0.000	0.999	0.001
M31.7 Microscopic polyangiitis	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
H05.4 Enophthalmos	0.001	0.999	0.000
Q55.6 Other congenital malformations of penis	0.001	0.999	0.000
T42.1 Iminostilbenes	0.000	0.999	0.001
Z89.6 Acquired absence of leg above knee	0.001	0.999	0.000
M24.02 Loose body in joint (Upper arm)	0.001	0.999	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.001	0.999	0.000
M89 Other disorders of bone	0.000	0.999	0.001
M24.96 Joint derangement, unspecified (Lower leg)	0.001	0.999	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.999	0.001
F43.0 Acute stress reaction	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.000	0.999	0.001
S42.7 Multiple fractures of clavicle, scapula and humerus	0.000	0.999	0.001
C52 Malignant neoplasm of vagina	0.001	0.999	0.000
W06 Fall involving bed	0.000	0.999	0.001
B37.9 Candidiasis, unspecified	0.000	0.999	0.001
F64.0 Transsexualism	0.000	0.999	0.001
H83.3 Noise effects on inner ear	0.000	0.999	0.001
S42.8 Fracture of other parts of shoulder and upper arm	0.000	0.999	0.001
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.999	0.001
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.001	0.999	0.000
V28.5 Passenger injured in traffic accident	0.000	0.999	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.999	0.001
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
M89.5 Osteolysis	0.000	0.999	0.001
O71.9 Obstetric trauma, unspecified	0.000	0.999	0.001
O71.5 Other obstetric injury to pelvic organs	0.000	0.999	0.001
Q24.5 Malformation of coronary vessels	0.001	0.999	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.001	0.999	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.001	0.999	0.000
Q55.5 Congenital absence and aplasia of penis	0.001	0.999	0.000
Q55.3 Atresia of vas deferens	0.001	0.999	0.000
Q55.1 Hypoplasia of testis and scrotum	0.001	0.999	0.000
Q55.0 Absence and aplasia of testis	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.999	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.999	0.000
M24.64 Ankylosis of joint (Hand)	0.001	0.999	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.999	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.999	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.999	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.001	0.999	0.000
M24.98 Joint derangement, unspecified (Other)	0.001	0.999	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.001	0.999	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M24.94 Joint derangement, unspecified (Hand)	0.001	0.999	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.001	0.999	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.001	0.999	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.001	0.999	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.001	0.999	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
M31.0 Hypersensitivity angiitis	0.001	0.999	0.000
S62.5 Fracture of thumb	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.000	0.999	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
S42.1 Fracture of scapula	0.000	0.999	0.001
C57 Malignant neoplasm of other and unspecified female genital organs	0.001	0.999	0.000
H83 Other diseases of inner ear	0.000	0.999	0.001
M24.51 Contracture of joint (Shoulder region)	0.001	0.999	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.999	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.001	0.999	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.000	0.999	0.001
G96.9 Disorder of central nervous system, unspecified	0.001	0.999	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
M54.6 Pain in thoracic spine	0.001	0.999	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.999	0.001
O71.3 Obstetric laceration of cervix	0.000	0.999	0.001
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
Y42.4 Oral contraceptives	0.000	0.999	0.001
C37 Malignant neoplasm of thymus	0.000	0.999	0.001
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.000	0.999	0.001
C25.4 Endocrine pancreas	0.000	0.999	0.001
M89.6 Osteopathy after poliomyelitis	0.000	0.999	0.001
M89.2 Other disorders of bone development and growth	0.000	0.999	0.001
M89.1 Epiphyseal arrest	0.000	0.999	0.001
W06.1 Residential institution	0.000	0.999	0.001
W55.0 Home	0.000	0.999	0.001
Z43.5 Attention to cyctostomy	0.000	0.999	0.001
Z94.4 Liver transplant status	0.000	0.999	0.001
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.999	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.000	0.999	0.001
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.000	0.999	0.001
C57.8 Overlapping lesion of female genital organs	0.001	0.999	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.001	0.999	0.000
W06.2 School, other institution and public administrative area	0.000	0.999	0.001
W06.8 Other specified place	0.000	0.999	0.001
W06.7 Farm	0.000	0.999	0.001
W06.6 Industrial and construction area	0.000	0.999	0.001
W06.5 Trade and service area	0.000	0.999	0.001
W06.4 Street and highway	0.000	0.999	0.001
W06.3 Sports and athletics area	0.000	0.999	0.001
O71 Other obstetric trauma	0.000	0.999	0.001
G20-G26 Extrapyramidal and movement disorders	0.000	0.999	0.001
G23 Other degenerative diseases of basal ganglia	0.000	0.999	0.001
M89.59 Osteolysis (Site unspecified)	0.000	0.999	0.001
M89.58 Osteolysis (Other)	0.000	0.999	0.001
M89.57 Osteolysis (Ankle and foot)	0.000	0.999	0.001
M89.54 Osteolysis (Hand)	0.000	0.999	0.001
M89.53 Osteolysis (Forearm)	0.000	0.999	0.001
M89.52 Osteolysis (Upper arm)	0.000	0.999	0.001
M89.51 Osteolysis (Shoulder region)	0.000	0.999	0.001
M89.50 Osteolysis (Multiple sites)	0.000	0.999	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.999	0.001
H93 Other disorders of ear, not elsewhere classified	0.000	0.999	0.001
R81 Glycosuria	0.000	0.999	0.001
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.999	0.001
S42.11 Fracture of scapula (open)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations