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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2071540
log Bayes Factor = 75.202
Chromosome 6   position 32,812,916  (GRCh37) Explore rs2071540 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E11.9 Without complications
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.018 0.982
E10.8 With unspecified complications
0.000 0.018 0.982
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.018 0.982
E10.2 With renal complications
0.000 0.021 0.979
G35 Multiple sclerosis
0.978 0.022 0.000
E11.2 With renal complications
0.000 0.031 0.969
E10.0 With coma
0.000 0.042 0.958
E10.5 With peripheral circulatory complications
0.000 0.048 0.952
E11.3 With ophthalmic complications
0.000 0.083 0.917
E10.6 With other specified complications
0.000 0.141 0.859
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.143 0.857
H36.0 Diabetic retinopathy
0.000 0.161 0.839
E06 Thyroiditis
0.000 0.165 0.835
E14.6 With other specified complications
0.000 0.169 0.831
E11.1 With ketoacidosis
0.000 0.174 0.826
E14.8 With unspecified complications
0.000 0.182 0.818
E11.6 With other specified complications
0.000 0.182 0.818
E14.9 Without complications
0.000 0.187 0.813
E14.5 With peripheral circulatory complications
0.000 0.212 0.788
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.224 0.776
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.227 0.773
E14.1 With ketoacidosis
0.000 0.252 0.748
E11.8 With unspecified complications
0.000 0.257 0.743
E13 Other specified diabetes mellitus
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E14.7 With multiple complications
0.000 0.286 0.714
E14.0 With coma
0.000 0.286 0.714
E06.3 Autoimmune thyroiditis
0.000 0.294 0.706
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.305 0.695
E03.1 Congenital hypothyroidism without goitre
0.000 0.321 0.679
E14.4 With neurological complications
0.000 0.339 0.661
E06.5 Other chronic thyroiditis
0.000 0.341 0.659
E40-E46 Malnutrition
0.000 0.346 0.654
E11.0 With coma
0.000 0.359 0.641
E11.4 With neurological complications
0.000 0.363 0.637
E11.5 With peripheral circulatory complications
0.000 0.369 0.631
E14.2 Withrenal complications
0.000 0.371 0.629
E06.4 Drug-induced thyroiditis
0.000 0.401 0.599
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.401 0.599
E06.0 Acute thyroiditis
0.000 0.401 0.599
E03.8 Other specified hypothyroidism
0.000 0.406 0.594
E20-E35 Disorders of other endocrine glands
0.000 0.407 0.593
E06.1 Subacute thyroiditis
0.000 0.420 0.579
E06.9 Thyroiditis, unspecified
0.000 0.432 0.567
E13.3 With ophthalmic complications
0.000 0.464 0.536
E16.1 Other hypoglycaemia
0.000 0.465 0.534
E23 Hypofunction and other disorders of pituitary gland
0.000 0.479 0.521
E13.8 With unspecified complications
0.000 0.481 0.519
E13.7 With multiple complications
0.000 0.481 0.519
E13.6 With other specified complications
0.000 0.481 0.519
E13.5 With peripheral circulatory complications
0.000 0.481 0.519
E13.4 With neurological complications
0.000 0.481 0.519
E13.2 With renal complications
0.000 0.481 0.519
E13.1 With ketoacidosis
0.000 0.481 0.519
E13.0 With coma
0.000 0.481 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E07 Other disorders of thyroid
0.000 0.486 0.514
E13.9 Without complications
0.000 0.494 0.506
E05.8 Other thyrotoxicosis
0.001 0.499 0.501
E24 Cushing's syndrome
0.000 0.500 0.500
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.515 0.485
E04 Other non-toxic goitre
0.000 0.516 0.484
E50-E64 Other nutritional deficiencies
0.000 0.520 0.480
J45.9 Asthma, unspecified
0.000 0.529 0.471
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.531 0.469
E45 Retarded development following protein-energy malnutrition
0.000 0.531 0.469
E43 Unspecified severe protein-energy malnutrition
0.000 0.531 0.469
E42 Marasmic kwashiorkor
0.000 0.531 0.469
E41 Nutritional marasmus
0.000 0.531 0.469
E40 Kwashiorkor
0.000 0.531 0.469
E23.2 Diabetes insipidus
0.000 0.535 0.465
E28 Ovarian dysfunction
0.000 0.542 0.458
E23.7 Disorder of pituitary gland, unspecified
0.000 0.551 0.449
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.561 0.439
E25 Adrenogenital disorders
0.000 0.569 0.431
E04.0 Non-toxic diffuse goitre
0.000 0.572 0.428
E61 Deficiency of other nutrient elements
0.000 0.574 0.426
K90 Intestinal malabsorption
0.000 0.574 0.426
M35.3 Polymyalgia rheumatica
0.000 0.574 0.426
E20 Hypoparathyroidism
0.000 0.575 0.425
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.575 0.425
E32 Diseases of thymus
0.000 0.575 0.425
E30 Disorders of puberty, not elsewhere classified
0.000 0.575 0.425
E29 Testicular dysfunction
0.000 0.582 0.418
M06.9 Rheumatoid arthritis, unspecified
0.000 0.589 0.411
E46 Unspecified protein-energy malnutrition
0.000 0.594 0.406
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.597 0.403
E28.3 Primary ovarian failure
0.000 0.598 0.402
E24.0 Pituitary-dependent Cushing's disease
0.000 0.598 0.401
E61.1 Iron deficiency
0.000 0.600 0.400
E23.6 Other disorders of pituitary gland
0.000 0.601 0.399
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.602 0.398
E24.2 Drug-induced Cushing's syndrome
0.000 0.602 0.397
E31 Polyglandular dysfunction
0.000 0.607 0.393
E07.8 Other specified disorders of thyroid
0.000 0.613 0.387
E26 Hyperaldosteronism
0.000 0.619 0.381
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.626 0.373
E23.1 Drug-induced hypopituitarism
0.000 0.626 0.373
H36 Retinal disorders in diseases classified elsewhere
0.000 0.630 0.370
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.631 0.369
E07.1 Dyshormogenetic goitre
0.000 0.631 0.368
E07.0 Hypersecretion of calcitonin
0.000 0.631 0.368
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.631 0.369
E24.9 Cushing's syndrome, unspecified
0.000 0.632 0.368
E22 Hyperfunction of pituitary gland
0.000 0.638 0.362
E24.8 Other Cushing's syndrome
0.000 0.641 0.359
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.641 0.359
E24.3 Ectopic ACTH syndrome
0.000 0.641 0.359
E24.1 Nelson's syndrome
0.000 0.641 0.359
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.642 0.358
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.642 0.358
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.645 0.355
E54 Ascorbic acid deficiency
0.000 0.650 0.350
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.650 0.350
E04.8 Other specified non-toxic goitre
0.000 0.653 0.347
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.655 0.344
E50 Vitamin A deficiency
0.001 0.655 0.344
E60 Dietary zinc deficiency
0.001 0.655 0.344
E59 Dietary selenium deficiency
0.001 0.655 0.344
E52 Niacin deficiency [pellagra]
0.001 0.655 0.344
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.658 0.342
E63 Other nutritional deficiencies
0.000 0.658 0.342
E44.1 Mild protein-energy malnutrition
0.000 0.663 0.336
E44.0 Moderate protein-energy malnutrition
0.000 0.663 0.336
E28.9 Ovarian dysfunction, unspecified
0.000 0.672 0.328
E28.8 Other ovarian dysfunction
0.000 0.672 0.328
E28.1 Androgen excess
0.000 0.672 0.328
E28.0 Oestrogen excess
0.000 0.672 0.328
E51 Thiamine deficiency
0.001 0.674 0.326
E21.2 Other hyperparathyroidism
0.000 0.675 0.325
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.679 0.321
E29.1 Testicular hypofunction
0.000 0.682 0.318
G35-G37 Demyelinating diseases of the central nervous system
0.316 0.684 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.685 0.315
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.685 0.315
E56 Other vitamin deficiencies
0.001 0.687 0.313
E25.9 Adrenogenital disorder, unspecified
0.000 0.691 0.309
E25.8 Other adrenogenital disorders
0.000 0.691 0.309
E61.9 Deficiency of nutrient element, unspecified
0.000 0.694 0.306
E61.8 Deficiency of other specified nutrient elements
0.000 0.694 0.306
E61.7 Deficiency of multiple nutrient elements
0.000 0.694 0.306
E61.6 Vanadium deficiency
0.000 0.694 0.306
E61.5 Molybdenum deficiency
0.000 0.694 0.306
E61.4 Chromium deficiency
0.000 0.694 0.306
E61.3 Manganese deficiency
0.000 0.694 0.306
E61.0 Copper deficiency
0.000 0.694 0.306
K90.3 Pancreatic steatorrhoea
0.000 0.694 0.305
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.694 0.305
K90.1 Tropical sprue
0.000 0.694 0.305
E20.9 Hypoparathyroidism, unspecified
0.000 0.695 0.305
E20.8 Other hypoparathyroidism
0.000 0.695 0.305
E20.1 Pseudohypoparathyroidism
0.000 0.695 0.305
E20.0 Idiopathic hypoparathyroidism
0.000 0.695 0.305
E30.9 Disorder of puberty, unspecified
0.000 0.695 0.305
E30.8 Other disorders of puberty
0.000 0.695 0.305
E30.1 Precocious puberty
0.000 0.695 0.305
E30.0 Delayed puberty
0.000 0.695 0.305
E32.9 Disease of thymus, unspecified
0.000 0.695 0.305
E32.8 Other diseases of thymus
0.000 0.695 0.305
E32.1 Abscess of thymus
0.000 0.695 0.305
E32.0 Persistent hyperplasia of thymus
0.000 0.695 0.305
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.695 0.305
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.695 0.305
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.695 0.305
E21.4 Other specified disorders of parathyroid gland
0.000 0.695 0.304
E29.8 Other testicular dysfunction
0.000 0.700 0.300
E29.0 Testicular hyperfunction
0.000 0.700 0.300
E21.3 Hyperparathyroidism, unspecified
0.000 0.704 0.296
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.704 0.296
K90.8 Other intestinal malabsorption
0.000 0.705 0.295
E04.2 Non-toxic multinodular goitre
0.000 0.710 0.290
E53 Deficiency of other B group vitamins
0.000 0.710 0.289
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.717 0.283
E31.9 Polyglandular dysfunction, unspecified
0.000 0.718 0.282
E31.8 Other polyglandular dysfunction
0.000 0.718 0.282
E31.1 Polyglandular hyperfunction
0.000 0.718 0.282
E26.8 Other hyperaldosteronism
0.000 0.727 0.273
E26.1 Secondary hyperaldosteronism
0.000 0.727 0.273
E65-E68 Obesity and other hyperalimentation
0.000 0.728 0.272
E26.9 Hyperaldosteronism, unspecified
0.000 0.728 0.271
E22.0 Acromegaly and pituitary gigantism
0.000 0.729 0.271
E29.9 Testicular dysfunction, unspecified
0.000 0.731 0.269
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.735 0.265
E22.8 Other hyperfunction of pituitary gland
0.000 0.740 0.259
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.743 0.257
E61.2 Magnesium deficiency
0.000 0.749 0.251
E31.0 Autoimmune polyglandular failure
0.000 0.751 0.249
E50.9 Vitamin A deficiency, unspecified
0.000 0.753 0.247
E50.8 Other manifestations of vitamin A deficiency
0.000 0.753 0.247
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.753 0.247
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.753 0.247
E50.5 Vitamin A deficiency with night blindness
0.000 0.753 0.247
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.753 0.247
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.753 0.247
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.753 0.247
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.753 0.247
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.753 0.247
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.753 0.247
E64.8 Sequelae of other nutritional deficiencies
0.000 0.753 0.247
E64.3 Sequelae of rickets
0.000 0.753 0.247
E64.2 Sequelae of vitamin C deficiency
0.000 0.753 0.247
E64.1 Sequelae of vitamin A deficiency
0.000 0.753 0.247
E64.0 Sequelae of protein-energy malnutrition
0.000 0.753 0.247
E22.1 Hyperprolactinaemia
0.000 0.753 0.247
E63.8 Other specified nutritional deficiencies
0.001 0.754 0.245
E63.1 Imbalance of constituents of food intake
0.001 0.754 0.245
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.754 0.245
E63.9 Nutritional deficiency, unspecified
0.000 0.757 0.243
E51.9 Thiamine deficiency, unspecified
0.001 0.766 0.234
E51.8 Other manifestations of thiamine deficiency
0.001 0.766 0.234
E51.1 Beriberi
0.001 0.766 0.234
E58 Dietary calcium deficiency
0.001 0.767 0.232
E26.0 Primary hyperaldosteronism
0.000 0.768 0.231
E28.2 Polycystic ovarian syndrome
0.000 0.769 0.231
E27 Other disorders of adrenal gland
0.000 0.769 0.231
E04.9 Non-toxic goitre, unspecified
0.000 0.770 0.230
E34 Other endocrine disorders
0.001 0.770 0.229
E56.9 Vitamin deficiency, unspecified
0.001 0.775 0.224
E56.8 Deficiency of other vitamins
0.001 0.775 0.224
E56.0 Deficiency of vitamin E
0.001 0.775 0.224
E53.9 Vitamin B deficiency, unspecified
0.000 0.781 0.219
E21.0 Primary hyperparathyroidism
0.000 0.782 0.218
G36 Other acute disseminated demyelination
0.216 0.784 0.000
E51.2 Wernicke's encephalopathy
0.001 0.784 0.215
K90.9 Intestinal malabsorption, unspecified
0.000 0.785 0.215
E55 Vitamin D deficiency
0.001 0.788 0.211
E53.1 Pyridoxine deficiency
0.000 0.792 0.208
E53.0 Riboflavin deficiency
0.000 0.792 0.208
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.800 0.200
G37 Other demyelinating diseases of central nervous system
0.195 0.805 0.000
E67 Other hyperalimentation
0.000 0.805 0.195
E68 Sequelae of hyperalimentation
0.000 0.805 0.195
E27.1 Primary adrenocortical insufficiency
0.000 0.805 0.195
E56.1 Deficiency of vitamin K
0.001 0.806 0.193
E23.0 Hypopituitarism
0.000 0.818 0.182
E27.8 Other specified disorders of adrenal gland
0.000 0.820 0.180
E34.3 Short stature, not elsewhere classified
0.001 0.832 0.167
E27.5 Adrenomedullary hyperfunction
0.000 0.834 0.166
E27.0 Other adrenocortical overactivity
0.000 0.834 0.166
E34.5 Androgen resistance syndrome
0.001 0.835 0.165
E34.4 Constitutional tall stature
0.001 0.835 0.165
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.835 0.165
E34.1 Other hypersecretion of intestinal hormones
0.001 0.835 0.165
E34.8 Other specified endocrine disorders
0.001 0.842 0.157
G36.9 Acute disseminated demyelination, unspecified
0.155 0.845 0.000
G36.8 Other specified acute disseminated demyelination
0.155 0.845 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.155 0.845 0.000
E55.0 Rickets, active
0.001 0.848 0.151
J45 Asthma
0.000 0.851 0.149
G37.8 Other specified demyelinating diseases of central nervous system
0.148 0.851 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.855 0.145
G36.0 Neuromyelitis optica [Devic]
0.144 0.855 0.000
G37.5 Concentric sclerosis [Balo]
0.140 0.860 0.000
G37.4 Subacute necrotising myelitis
0.140 0.860 0.000
G37.2 Central pontine myelinolysis
0.140 0.860 0.000
G37.1 Central demyelination of corpus callosum
0.140 0.860 0.000
G37.0 Diffuse sclerosis
0.140 0.860 0.000
E67.8 Other specified hyperalimentation
0.000 0.860 0.140
E67.3 Hypervitaminosis D
0.000 0.860 0.140
E67.2 Megavitamin-B6 syndrome
0.000 0.860 0.140
E67.1 Hypercarotenaemia
0.000 0.860 0.140
E67.0 Hypervitaminosis A
0.000 0.860 0.140
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.862 0.138
E04.1 Non-toxic single thyroid nodule
0.000 0.863 0.137
G37.9 Demyelinating disease of central nervous system, unspecified
0.135 0.865 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.870 0.130
E27.2 Addisonian crisis
0.000 0.870 0.130
E34.0 Carcinoid syndrome
0.001 0.879 0.120
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.885 0.115
E07.9 Disorder of thyroid, unspecified
0.000 0.886 0.113
E27.9 Disorder of adrenal gland, unspecified
0.000 0.892 0.107
E65 Localised adiposity
0.001 0.894 0.106
J45.1 Nonallergic asthma
0.000 0.896 0.104
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.101 0.898 0.000
M06 Other rheumatoid arthritis
0.000 0.900 0.100
N04 Nephrotic syndrome
0.000 0.900 0.100
N00-N08 Glomerular diseases
0.000 0.901 0.099
N04.9 Unspecified
0.000 0.903 0.097
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.911 0.089
E34.9 Endocrine disorder, unspecified
0.001 0.914 0.085
N04.2 Diffuse membranous glomerulonephritis
0.000 0.915 0.085
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.917 0.083
N04.1 Focal and segmental glomerular lesions
0.000 0.917 0.083
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.917 0.083
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.917 0.083
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.917 0.083
J45.8 Mixed asthma
0.000 0.917 0.082
J45.0 Predominantly allergic asthma
0.000 0.918 0.082
N05 Unspecified nephritic syndrome
0.000 0.920 0.080
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.924 0.075
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.925 0.075
M06.4 Inflammatory polyarthropathy
0.000 0.927 0.073
M35 Other systemic involvement of connective tissue
0.000 0.928 0.072
M06.2 Rheumatoid bursitis
0.000 0.928 0.072
N04.8 Other
0.000 0.928 0.072
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.928 0.072
N04.6 Dense deposit disease
0.000 0.928 0.072
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.928 0.072
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.928 0.072
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.928 0.072
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.929 0.071
N06 Isolated proteinuria with specified morphological lesion
0.000 0.929 0.071
N01 Rapidly progressive nephritic syndrome
0.000 0.929 0.071
N00 Acute nephritic syndrome
0.000 0.929 0.071
M06.3 Rheumatoid nodule
0.000 0.929 0.071
N02 Recurrent and persistent haematuria
0.000 0.932 0.068
J43.9 Emphysema, unspecified
0.000 0.933 0.067
N05.1 Focal and segmental glomerular lesions
0.000 0.933 0.067
M06.1 Adult-onset Still's disease
0.000 0.934 0.065
N04.0 Minor glomerular abnormality
0.000 0.935 0.065
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.935 0.065
M35.7 Hypermobility syndrome
0.000 0.935 0.065
J43 Emphysema
0.000 0.936 0.064
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.937 0.063
J40-J47 Chronic lower respiratory diseases
0.000 0.938 0.062
M06.8 Other specified rheumatoid arthritis
0.000 0.939 0.060
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.940 0.060
N02.2 Diffuse membranous glomerulonephritis
0.000 0.940 0.060
N05.6 Dense deposit disease
0.000 0.942 0.057
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.942 0.057
N05.0 Minor glomerular abnormality
0.000 0.942 0.057
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.943 0.057
N05.2 Diffuse membranous glomerulonephritis
0.000 0.944 0.056
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.944 0.056
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.944 0.056
N05.9 Unspecified
0.000 0.945 0.055
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.947 0.053
J44 Other chronic obstructive pulmonary disease
0.000 0.947 0.053
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.947 0.052
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.947 0.052
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.947 0.052
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.947 0.052
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.947 0.052
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.947 0.052
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.947 0.052
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.948 0.052
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.948 0.052
M35.5 Multifocal fibrosclerosis
0.000 0.948 0.052
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.948 0.052
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.948 0.051
M06.28 Rheumatoid bursitis (Other)
0.000 0.948 0.051
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.948 0.051
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.948 0.051
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.948 0.051
M06.24 Rheumatoid bursitis (Hand)
0.000 0.948 0.051
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.948 0.051
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.948 0.051
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.948 0.051
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.948 0.051
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.948 0.051
J43.2 Centrilobular emphysema
0.000 0.949 0.051
N00.9 Unspecified
0.000 0.949 0.051
N00.8 Other
0.000 0.949 0.051
N00.7 Diffuse crescentic glomerulonephritis
0.000 0.949 0.051
N00.6 Dense deposit disease
0.000 0.949 0.051
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.949 0.051
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.949 0.051
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.949 0.051
N00.2 Diffuse membranous glomerulonephritis
0.000 0.949 0.051
N00.1 Focal and segmental glomerular lesions
0.000 0.949 0.051
N00.0 Minor glomerular abnormality
0.000 0.949 0.051
N01.9 Unspecified
0.000 0.949 0.051
N01.8 Other
0.000 0.949 0.051
N01.7 Diffuse crescentic glomerulonephritis
0.000 0.949 0.051
N01.6 Dense deposit disease
0.000 0.949 0.051
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.949 0.051
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.949 0.051
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.949 0.051
N01.2 Diffuse membranous glomerulonephritis
0.000 0.949 0.051
N01.1 Focal and segmental glomerular lesions
0.000 0.949 0.051
N01.0 Minor glomerular abnormality
0.000 0.949 0.051
N06.9 Unspecified
0.000 0.949 0.051
N06.8 Other
0.000 0.949 0.051
N06.7 Diffuse crescentic glomerulonephritis
0.000 0.949 0.051
N06.6 Dense deposit disease
0.000 0.949 0.051
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.949 0.051
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.949 0.051
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.949 0.051
N06.2 Diffuse membranous glomerulonephritis
0.000 0.949 0.051
N06.1 Focal and segmental glomerular lesions
0.000 0.949 0.051
N06.0 Minor glomerular abnormality
0.000 0.949 0.051
N07.9 Unspecified
0.000 0.949 0.051
N07.8 Other
0.000 0.949 0.051
N07.7 Diffuse crescentic glomerulonephritis
0.000 0.949 0.051
N07.6 Dense deposit disease
0.000 0.949 0.051
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.949 0.051
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.949 0.051
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.949 0.051
N07.2 Diffuse membranous glomerulonephritis
0.000 0.949 0.051
N07.1 Focal and segmental glomerular lesions
0.000 0.949 0.051
N07.0 Minor glomerular abnormality
0.000 0.949 0.051
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.949 0.051
M06.38 Rheumatoid nodule (Other)
0.000 0.949 0.051
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.949 0.051
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.949 0.051
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.949 0.051
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.951 0.049
N02.7 Diffuse crescentic glomerulonephritis
0.000 0.951 0.049
N02.6 Dense deposit disease
0.000 0.951 0.049
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.951 0.049
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.951 0.049
N02.1 Focal and segmental glomerular lesions
0.000 0.951 0.049
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.951 0.049
M06.18 Adult-onset Still's disease (Other)
0.000 0.953 0.047
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.953 0.047
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.953 0.047
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.953 0.047
M06.14 Adult-onset Still's disease (Hand)
0.000 0.953 0.047
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.953 0.047
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.953 0.047
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.953 0.047
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.953 0.047
N02.0 Minor glomerular abnormality
0.000 0.953 0.047
M06.33 Rheumatoid nodule (Forearm)
0.000 0.954 0.046
J43.1 Panlobular emphysema
0.000 0.954 0.046
J43.0 MacLeod's syndrome
0.000 0.954 0.046
N05.8 Other
0.000 0.954 0.046
M35.1 Other overlap syndromes
0.000 0.955 0.045
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.955 0.045
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.956 0.043
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.956 0.043
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.956 0.043
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.956 0.043
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.956 0.043
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.956 0.043
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.956 0.043
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.956 0.043
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.956 0.043
J41 Simple and mucopurulent chronic bronchitis
0.000 0.957 0.043
K90-K93 Other diseases of the digestive system
0.000 0.958 0.042
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.959 0.041
I35.0 Aortic (valve) stenosis
0.000 0.959 0.041
M06.34 Rheumatoid nodule (Hand)
0.000 0.960 0.040
M06.0 Seronegative rheumatoid arthritis
0.000 0.960 0.040
M35.8 Other specified systemic involvement of connective tissue
0.000 0.960 0.040
J43.8 Other emphysema
0.000 0.960 0.040
N02.9 Unspecified
0.000 0.961 0.039
N02.8 Other
0.000 0.962 0.038
K12.1 Other forms of stomatitis
0.000 0.962 0.038
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.962 0.037
N03 Chronic nephritic syndrome
0.000 0.963 0.037
E83.1 Disorders of iron metabolism
0.037 0.963 0.000
J42 Unspecified chronic bronchitis
0.000 0.963 0.036
M35.2 Behcet's disease
0.000 0.964 0.036
M05-M14 Inflammatory polyarthropathies
0.000 0.964 0.036
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.965 0.035
M05 Seropositive rheumatoid arthritis
0.000 0.965 0.035
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.965 0.035

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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