TreeWAS – Variant ID: rs2073151

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
E20-E35 Disorders of other endocrine glands	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E10.3 With ophthalmic complications	0.000	0.001	0.999
E05.9 Thyrotoxicosis, unspecified	0.000	0.002	0.998
E27 Other disorders of adrenal gland	0.000	0.005	0.995
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.011	0.989
E10.2 With renal complications	0.000	0.012	0.988
E27.1 Primary adrenocortical insufficiency	0.000	0.013	0.987
E24 Cushing's syndrome	0.000	0.051	0.949
E14 Unspecified diabetes mellitus	0.000	0.053	0.947
E13 Other specified diabetes mellitus	0.000	0.057	0.943
E10.4 With neurological complications	0.000	0.060	0.940
E10.1 With ketoacidosis	0.000	0.070	0.930
E23 Hypofunction and other disorders of pituitary gland	0.000	0.092	0.908
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.097	0.903
E13.9 Without complications	0.000	0.098	0.902
E14.3 With ophthalmic complications	0.000	0.102	0.898
E50-E64 Other nutritional deficiencies	0.000	0.104	0.896
L40.9 Psoriasis, unspecified	0.889	0.111	0.000
E20 Hypoparathyroidism	0.000	0.112	0.888
E24.0 Pituitary-dependent Cushing's disease	0.000	0.145	0.855
E23.0 Hypopituitarism	0.000	0.156	0.844
E24.9 Cushing's syndrome, unspecified	0.000	0.178	0.822
E03 Other hypothyroidism	0.000	0.180	0.820
E05.8 Other thyrotoxicosis	0.000	0.184	0.816
E20.9 Hypoparathyroidism, unspecified	0.000	0.191	0.809
E22 Hyperfunction of pituitary gland	0.000	0.198	0.802
E29 Testicular dysfunction	0.000	0.201	0.799
E55 Vitamin D deficiency	0.000	0.202	0.798
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.208	0.792
E10.0 With coma	0.000	0.219	0.781
E14.6 With other specified complications	0.000	0.226	0.773
E53 Deficiency of other B group vitamins	0.000	0.230	0.770
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.250	0.750
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.253	0.747
E10.7 With multiple complications	0.000	0.255	0.745
E23.2 Diabetes insipidus	0.000	0.259	0.741
E51 Thiamine deficiency	0.000	0.260	0.739
E53.9 Vitamin B deficiency, unspecified	0.000	0.261	0.739
E14.2 Withrenal complications	0.000	0.264	0.736
E24.2 Drug-induced Cushing's syndrome	0.000	0.271	0.729
E55.9 Vitamin D deficiency, unspecified	0.000	0.272	0.728
E40-E46 Malnutrition	0.000	0.273	0.727
L40 Psoriasis	0.721	0.279	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.283	0.716
E32 Diseases of thymus	0.000	0.283	0.716
E30 Disorders of puberty, not elsewhere classified	0.000	0.283	0.716
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
E03.9 Hypothyroidism, unspecified	0.000	0.287	0.713
E27.5 Adrenomedullary hyperfunction	0.000	0.287	0.713
E27.0 Other adrenocortical overactivity	0.000	0.287	0.713
E25 Adrenogenital disorders	0.000	0.299	0.701
E14.5 With peripheral circulatory complications	0.000	0.300	0.700
E27.8 Other specified disorders of adrenal gland	0.000	0.309	0.691
E22.0 Acromegaly and pituitary gigantism	0.000	0.311	0.689
E10.6 With other specified complications	0.000	0.315	0.685
E10.8 With unspecified complications	0.000	0.315	0.685
E31 Polyglandular dysfunction	0.000	0.319	0.681
E14.8 With unspecified complications	0.000	0.319	0.681
E24.8 Other Cushing's syndrome	0.000	0.320	0.680
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.320	0.680
E24.3 Ectopic ACTH syndrome	0.000	0.320	0.680
E24.1 Nelson's syndrome	0.000	0.320	0.680
E14.7 With multiple complications	0.000	0.321	0.679
E14.0 With coma	0.000	0.321	0.679
E13.8 With unspecified complications	0.000	0.324	0.676
E13.7 With multiple complications	0.000	0.324	0.676
E13.6 With other specified complications	0.000	0.324	0.676
E13.5 With peripheral circulatory complications	0.000	0.324	0.676
E13.4 With neurological complications	0.000	0.324	0.676
E13.2 With renal complications	0.000	0.324	0.676
E13.1 With ketoacidosis	0.000	0.324	0.676
E13.0 With coma	0.000	0.324	0.676
E28 Ovarian dysfunction	0.000	0.326	0.674
E13.3 With ophthalmic complications	0.000	0.327	0.673
E06 Thyroiditis	0.000	0.339	0.661
E27.9 Disorder of adrenal gland, unspecified	0.000	0.340	0.660
E14.1 With ketoacidosis	0.000	0.340	0.660
E29.1 Testicular hypofunction	0.000	0.344	0.656
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.349	0.651
E23.1 Drug-induced hypopituitarism	0.000	0.349	0.651
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.357	0.643
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.357	0.643
E50 Vitamin A deficiency	0.000	0.357	0.643
E60 Dietary zinc deficiency	0.000	0.357	0.643
E59 Dietary selenium deficiency	0.000	0.357	0.643
E52 Niacin deficiency [pellagra]	0.000	0.357	0.643
E20.8 Other hypoparathyroidism	0.000	0.363	0.637
E20.1 Pseudohypoparathyroidism	0.000	0.363	0.637
E20.0 Idiopathic hypoparathyroidism	0.000	0.363	0.637
E61 Deficiency of other nutrient elements	0.000	0.363	0.637
K90 Intestinal malabsorption	0.000	0.364	0.636
L40.5 Arthropathic psoriasis	0.636	0.364	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.368	0.632
E14.4 With neurological complications	0.000	0.371	0.629
E51.2 Wernicke's encephalopathy	0.000	0.373	0.627
E23.7 Disorder of pituitary gland, unspecified	0.000	0.376	0.624
E10.5 With peripheral circulatory complications	0.000	0.377	0.623
E56 Other vitamin deficiencies	0.000	0.379	0.621
E22.1 Hyperprolactinaemia	0.000	0.390	0.610
E03.1 Congenital hypothyroidism without goitre	0.000	0.396	0.604
L40.8 Other psoriasis	0.601	0.399	0.000
E58 Dietary calcium deficiency	0.000	0.403	0.596
L40.0 Psoriasis vulgaris	0.595	0.405	0.000
E26 Hyperaldosteronism	0.000	0.405	0.595
E14.9 Without complications	0.000	0.411	0.589
E03.5 Myxoedema coma	0.000	0.412	0.588
E03.4 Atrophy of thyroid (acquired)	0.000	0.412	0.588
E03.3 Postinfectious hypothyroidism	0.000	0.412	0.588
E27.2 Addisonian crisis	0.000	0.413	0.587
E34 Other endocrine disorders	0.000	0.414	0.586
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.425	0.575
E22.8 Other hyperfunction of pituitary gland	0.000	0.425	0.575
E29.9 Testicular dysfunction, unspecified	0.000	0.427	0.573
E29.8 Other testicular dysfunction	0.000	0.427	0.573
E29.0 Testicular hyperfunction	0.000	0.427	0.573
E55.0 Rickets, active	0.000	0.428	0.572
E16 Other disorders of pancreatic internal secretion	0.000	0.435	0.565
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.438	0.562
E63 Other nutritional deficiencies	0.000	0.446	0.554
E53.1 Pyridoxine deficiency	0.000	0.448	0.552
E53.0 Riboflavin deficiency	0.000	0.448	0.552
E54 Ascorbic acid deficiency	0.000	0.454	0.545
E07 Other disorders of thyroid	0.000	0.455	0.545
E23.6 Other disorders of pituitary gland	0.000	0.464	0.536
E15 Nondiabetic hypoglycaemic coma	0.000	0.465	0.535
E46 Unspecified protein-energy malnutrition	0.000	0.469	0.531
E51.9 Thiamine deficiency, unspecified	0.000	0.470	0.530
E51.8 Other manifestations of thiamine deficiency	0.000	0.470	0.530
E51.1 Beriberi	0.000	0.470	0.530
K90.9 Intestinal malabsorption, unspecified	0.000	0.475	0.525
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.479	0.521
E45 Retarded development following protein-energy malnutrition	0.000	0.479	0.521
E43 Unspecified severe protein-energy malnutrition	0.000	0.479	0.521
E42 Marasmic kwashiorkor	0.000	0.479	0.521
E41 Nutritional marasmus	0.000	0.479	0.521
E40 Kwashiorkor	0.000	0.479	0.521
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.480	0.520
L40.2 Acrodermatitis continua	0.517	0.483	0.000
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E30.9 Disorder of puberty, unspecified	0.000	0.486	0.514
E30.8 Other disorders of puberty	0.000	0.486	0.514
E30.1 Precocious puberty	0.000	0.486	0.514
E30.0 Delayed puberty	0.000	0.486	0.514
E32.9 Disease of thymus, unspecified	0.000	0.486	0.514
E32.8 Other diseases of thymus	0.000	0.486	0.514
E32.1 Abscess of thymus	0.000	0.486	0.514
E32.0 Persistent hyperplasia of thymus	0.000	0.486	0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.486	0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.486	0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.513
L40.3 Pustulosis palmaris et plantaris	0.505	0.495	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.497	0.502
E25.8 Other adrenogenital disorders	0.000	0.497	0.502
L40.4 Guttate psoriasis	0.499	0.501	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.502	0.498
L40.1 Generalised pustular psoriasis	0.490	0.510	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.512	0.488
E31.8 Other polyglandular dysfunction	0.000	0.512	0.488
E31.1 Polyglandular hyperfunction	0.000	0.512	0.488
E06.3 Autoimmune thyroiditis	0.000	0.512	0.488
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.513	0.487
E03.8 Other specified hypothyroidism	0.000	0.514	0.486
E61.2 Magnesium deficiency	0.000	0.515	0.485
E28.9 Ovarian dysfunction, unspecified	0.000	0.516	0.483
E28.8 Other ovarian dysfunction	0.000	0.516	0.483
E28.1 Androgen excess	0.000	0.516	0.483
E28.0 Oestrogen excess	0.000	0.516	0.483
E06.9 Thyroiditis, unspecified	0.000	0.517	0.482
E06.4 Drug-induced thyroiditis	0.000	0.526	0.474
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.526	0.474
E06.1 Subacute thyroiditis	0.000	0.526	0.474
E06.0 Acute thyroiditis	0.000	0.526	0.474
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.532	0.468
E16.1 Other hypoglycaemia	0.000	0.538	0.462
E50.9 Vitamin A deficiency, unspecified	0.000	0.539	0.461
E50.8 Other manifestations of vitamin A deficiency	0.000	0.539	0.461
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.539	0.461
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.539	0.461
E50.5 Vitamin A deficiency with night blindness	0.000	0.539	0.461
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.539	0.461
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.539	0.461
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.539	0.461
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.539	0.461
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.539	0.461
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.539	0.461
E64.8 Sequelae of other nutritional deficiencies	0.000	0.539	0.461
E64.3 Sequelae of rickets	0.000	0.539	0.461
E64.2 Sequelae of vitamin C deficiency	0.000	0.539	0.461
E64.1 Sequelae of vitamin A deficiency	0.000	0.539	0.461
E64.0 Sequelae of protein-energy malnutrition	0.000	0.539	0.461
E61.9 Deficiency of nutrient element, unspecified	0.000	0.543	0.456
E61.8 Deficiency of other specified nutrient elements	0.000	0.543	0.456
E61.7 Deficiency of multiple nutrient elements	0.000	0.543	0.456
E61.6 Vanadium deficiency	0.000	0.543	0.456
E61.5 Molybdenum deficiency	0.000	0.543	0.456
E61.4 Chromium deficiency	0.000	0.543	0.456
E61.3 Manganese deficiency	0.000	0.543	0.456
E61.0 Copper deficiency	0.000	0.543	0.456
K90.3 Pancreatic steatorrhoea	0.000	0.544	0.456
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.544	0.456
K90.1 Tropical sprue	0.000	0.544	0.456
E31.0 Autoimmune polyglandular failure	0.000	0.547	0.452
E56.9 Vitamin deficiency, unspecified	0.000	0.554	0.445
E56.8 Deficiency of other vitamins	0.000	0.554	0.445
E56.0 Deficiency of vitamin E	0.000	0.554	0.445
E26.9 Hyperaldosteronism, unspecified	0.000	0.558	0.442
K90.8 Other intestinal malabsorption	0.000	0.560	0.440
E26.8 Other hyperaldosteronism	0.000	0.573	0.426
E26.1 Secondary hyperaldosteronism	0.000	0.573	0.426
E34.3 Short stature, not elsewhere classified	0.000	0.574	0.426
E56.1 Deficiency of vitamin K	0.000	0.576	0.424
E28.3 Primary ovarian failure	0.000	0.578	0.421
E34.5 Androgen resistance syndrome	0.000	0.580	0.420
E34.4 Constitutional tall stature	0.000	0.580	0.420
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.580	0.420
E34.1 Other hypersecretion of intestinal hormones	0.000	0.580	0.420
E61.1 Iron deficiency	0.000	0.585	0.415
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.595	0.405
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.595	0.405
E16.4 Abnormal secretion of gastrin	0.000	0.595	0.405
E16.3 Increased secretion of glucagon	0.000	0.595	0.405
E63.8 Other specified nutritional deficiencies	0.000	0.603	0.397
E63.1 Imbalance of constituents of food intake	0.000	0.603	0.397
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.603	0.397
E07.1 Dyshormogenetic goitre	0.000	0.609	0.391
E07.0 Hypersecretion of calcitonin	0.000	0.609	0.391
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.613	0.387
E34.8 Other specified endocrine disorders	0.000	0.613	0.386
E06.5 Other chronic thyroiditis	0.000	0.614	0.386
E16.2 Hypoglycaemia, unspecified	0.000	0.617	0.383
E34.9 Endocrine disorder, unspecified	0.000	0.620	0.380
E34.0 Carcinoid syndrome	0.000	0.620	0.380
E44.1 Mild protein-energy malnutrition	0.000	0.626	0.374
E44.0 Moderate protein-energy malnutrition	0.000	0.626	0.374
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.651	0.349
E07.9 Disorder of thyroid, unspecified	0.000	0.672	0.328
E07.8 Other specified disorders of thyroid	0.000	0.685	0.314
E63.9 Nutritional deficiency, unspecified	0.001	0.691	0.308
E26.0 Primary hyperaldosteronism	0.001	0.724	0.275
E65-E68 Obesity and other hyperalimentation	0.000	0.741	0.259
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.796	0.204
E67 Other hyperalimentation	0.000	0.814	0.186
E68 Sequelae of hyperalimentation	0.000	0.814	0.186
E21.4 Other specified disorders of parathyroid gland	0.000	0.854	0.146
E21.2 Other hyperparathyroidism	0.000	0.861	0.139
E53.8 Deficiency of other specified B group vitamins	0.000	0.862	0.138
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.862	0.138
E11 Non-insulin-dependent diabetes mellitus	0.000	0.864	0.136
E67.8 Other specified hyperalimentation	0.000	0.866	0.133
E67.3 Hypervitaminosis D	0.000	0.866	0.133
E67.2 Megavitamin-B6 syndrome	0.000	0.866	0.133
E67.1 Hypercarotenaemia	0.000	0.866	0.133
E67.0 Hypervitaminosis A	0.000	0.866	0.133
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.873	0.126
E11.9 Without complications	0.000	0.876	0.124
E11.6 With other specified complications	0.000	0.893	0.107
L40-L45 Papulosquamous disorders	0.106	0.893	0.001
E11.2 With renal complications	0.000	0.900	0.100
E11.7 With multiple complications	0.000	0.902	0.098
E04 Other non-toxic goitre	0.001	0.904	0.094
E65 Localised adiposity	0.001	0.905	0.094
E11.8 With unspecified complications	0.000	0.906	0.094
E21.3 Hyperparathyroidism, unspecified	0.000	0.912	0.088
E11.0 With coma	0.000	0.920	0.080
L44 Other papulosquamous disorders	0.076	0.923	0.001
L41 Parapsoriasis	0.076	0.923	0.001
L45 Papulosquamous disorders in diseases classified elsewhere	0.076	0.923	0.001
M35.0 Sicca syndrome [Sjogren]	0.000	0.930	0.070
E04.8 Other specified non-toxic goitre	0.001	0.931	0.068
E04.9 Non-toxic goitre, unspecified	0.000	0.935	0.064
E83 Disorders of mineral metabolism	0.064	0.936	0.001
E11.1 With ketoacidosis	0.000	0.938	0.061
L42 Pityriasis rosea	0.055	0.944	0.001
L41.9 Parapsoriasis, unspecified	0.055	0.945	0.001
L41.8 Other parapsoriasis	0.055	0.945	0.001
L41.5 Retiform parapsoriasis	0.055	0.945	0.001
L41.4 Large plaque parapsoriasis	0.055	0.945	0.001
L41.3 Small plaque parapsoriasis	0.055	0.945	0.001
L41.2 Lymphomatoid papulosis	0.055	0.945	0.001
L41.1 Pityriasis lichenoides chronica	0.055	0.945	0.001
L41.0 Pityriasis lichenoides et varioliformis acuta	0.055	0.945	0.001
L44.9 Papulosquamous disorder, unspecified	0.055	0.945	0.001
L44.8 Other specified papulosquamous disorders	0.055	0.945	0.001
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.055	0.945	0.001
L44.3 Lichen ruber moniliformis	0.055	0.945	0.001
L44.2 Lichen striatus	0.055	0.945	0.001
L44.1 Lichen nitidus	0.055	0.945	0.001
L44.0 Pityriasis rubra pilaris	0.055	0.945	0.001
E83.8 Other disorders of mineral metabolism	0.046	0.954	0.001
E83.2 Disorders of zinc metabolism	0.046	0.954	0.001
E83.0 Disorders of copper metabolism	0.046	0.954	0.001
E83.9 Disorder of mineral metabolism, unspecified	0.045	0.954	0.001
E04.0 Non-toxic diffuse goitre	0.002	0.958	0.041
E11.5 With peripheral circulatory complications	0.000	0.958	0.041
K90-K93 Other diseases of the digestive system	0.000	0.959	0.040
E83.3 Disorders of phosphorus metabolism	0.039	0.960	0.000
E21.0 Primary hyperparathyroidism	0.000	0.961	0.039
L43 Lichen planus	0.032	0.967	0.002
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.971	0.029
C50.3 Lower-inner quadrant of breast	0.000	0.975	0.025
E11.4 With neurological complications	0.000	0.975	0.025
L43.3 Subacute (active) lichen planus	0.023	0.976	0.001
L43.2 Lichenoid drug reaction	0.023	0.976	0.001
L43.1 Bullous lichen planus	0.023	0.976	0.001
L43.0 Hypertrophic lichen planus	0.023	0.976	0.001
E11.3 With ophthalmic complications	0.000	0.978	0.022
E66 Obesity	0.000	0.978	0.022
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.979	0.021
K93.1 Megacolon in Chagas' disease	0.000	0.979	0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.979	0.021
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.981	0.019
E83.4 Disorders of magnesium metabolism	0.018	0.982	0.000
L43.8 Other lichen planus	0.016	0.983	0.002
E66.1 Drug-induced obesity	0.000	0.984	0.016
E66.0 Obesity due to excess calories	0.000	0.986	0.014
H26.9 Cataract, unspecified	0.000	0.986	0.014
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.013	0.987	0.000
M35 Other systemic involvement of connective tissue	0.000	0.990	0.010
C50.1 Central portion of breast	0.000	0.990	0.010
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.990	0.009
C50 Malignant neoplasm of breast	0.000	0.990	0.010
C50.8 Overlapping lesion of breast	0.000	0.990	0.010
H90.2 Conductive hearing loss, unspecified	0.000	0.991	0.009
H90 Conductive and sensorineural hearing loss	0.000	0.991	0.009
H90.3 Sensorineural hearing loss, bilateral	0.000	0.991	0.009
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.991	0.009
E04.2 Non-toxic multinodular goitre	0.001	0.992	0.007
C50.0 Nipple and areola	0.000	0.992	0.008
E83.5 Disorders of calcium metabolism	0.008	0.992	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.992	0.006
H90.5 Sensorineural hearing loss, unspecified	0.000	0.992	0.008
M35.8 Other specified systemic involvement of connective tissue	0.000	0.992	0.008
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.992	0.008
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.992	0.008
M35.5 Multifocal fibrosclerosis	0.000	0.992	0.008
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.992	0.008
X41.9 Unspecified place	0.008	0.992	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.992	0.008
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.992	0.008
A08.4 Viral intestinal infection, unspecified	0.000	0.993	0.007
M35.2 Behcet's disease	0.000	0.993	0.007
M35.1 Other overlap syndromes	0.000	0.993	0.007
B97 Viral agents as the cause of diseases classified to other chapters	0.007	0.993	0.000
M22.2 Patellofemoral disorders	0.000	0.993	0.007
H26 Other cataract	0.000	0.993	0.007
H26.4 After-cataract	0.000	0.993	0.007
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.993	0.006
S82.10 Fracture of upper end of tibia (closed)	0.000	0.994	0.006
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.006	0.994	0.000
M35.7 Hypermobility syndrome	0.000	0.994	0.006
H26.1 Traumatic cataract	0.000	0.994	0.006
C50.6 Axillary tail of breast	0.000	0.994	0.006
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.994	0.006
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.994	0.006
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
H26.2 Complicated cataract	0.000	0.995	0.005
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.005	0.995	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.995	0.005
H26.3 Drug-induced cataract	0.000	0.995	0.005
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.995	0.005
A87.9 Viral meningitis, unspecified	0.000	0.995	0.005
C50.4 Upper-outer quadrant of breast	0.000	0.996	0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
C50-C50 Malignant neoplasm of breast	0.000	0.996	0.004
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
L43.9 Lichen planus, unspecified	0.002	0.996	0.002
K92 Other diseases of digestive system	0.002	0.996	0.002
M31.6 Other giant cell arteritis	0.000	0.996	0.004
E70-E90 Metabolic disorders	0.001	0.996	0.003
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.996	0.004
X41.0 Home	0.004	0.996	0.000
X41.8 Other specified place	0.004	0.996	0.000
X41.7 Farm	0.004	0.996	0.000
X41.6 Industrial and construction area	0.004	0.996	0.000
X41.5 Trade and service area	0.004	0.996	0.000
X41.4 Street and highway	0.004	0.996	0.000
X41.3 Sports and athletics area	0.004	0.996	0.000
X41.2 School, other institution and public administrative area	0.004	0.996	0.000
X41.1 Residential institution	0.004	0.996	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.996	0.004
A08 Viral and other specified intestinal infections	0.000	0.996	0.004
M22 Disorders of patella	0.000	0.996	0.004
M34.1 CR(E)ST syndrome	0.000	0.996	0.004
A08.3 Other viral enteritis	0.000	0.997	0.003
M34 Systemic sclerosis	0.000	0.997	0.003
L53.9 Erythematous condition, unspecified	0.003	0.997	0.000
E73 Lactose intolerance	0.000	0.997	0.003
M34.9 Systemic sclerosis, unspecified	0.000	0.997	0.003
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.997	0.003
K91.1 Postgastric surgery syndromes	0.000	0.997	0.003
M22.8 Other disorders of patella	0.000	0.997	0.003
D47.4 Osteomyelofibrosis	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.000	0.997	0.003
E79 Disorders of purine and pyrimidine metabolism	0.001	0.997	0.003
B02.2 Zoster with other nervous system involvement	0.000	0.997	0.003
M22.0 Recurrent dislocation of patella	0.000	0.997	0.003
V18.0 Driver injured in nontraffic accident	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
E70 Disorders of aromatic amino-acid metabolism	0.001	0.997	0.003
A08.0 Rotaviral enteritis	0.000	0.997	0.003
C50.5 Lower-outer quadrant of breast	0.000	0.997	0.003
E73.9 Lactose intolerance, unspecified	0.000	0.997	0.003
K92.8 Other specified diseases of digestive system	0.002	0.997	0.001
H26.0 Infantile, juvenile and presenile cataract	0.002	0.997	0.001
E77 Disorders of glycoprotein metabolism	0.001	0.997	0.002
E76 Disorders of glycosaminoglycan metabolism	0.001	0.997	0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.997	0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.997	0.002
L27 Dermatitis due to substances taken internally	0.000	0.997	0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.003	0.997	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.003	0.997	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.997	0.002
A08.5 Other specified intestinal infections	0.000	0.997	0.003
A08.2 Adenoviral enteritis	0.000	0.997	0.003
C50.2 Upper-inner quadrant of breast	0.000	0.997	0.003
M22.1 Recurrent subluxation of patella	0.000	0.997	0.003
M22.9 Disorder of patella, unspecified	0.000	0.997	0.003
E84 Cystic fibrosis	0.001	0.997	0.002
E72 Other disorders of amino-acid metabolism	0.001	0.997	0.002
V17.4 Driver injured in traffic accident	0.003	0.997	0.000
K92.0 Haematemesis	0.003	0.997	0.000
A87 Viral meningitis	0.000	0.997	0.003
E66.8 Other obesity	0.000	0.997	0.003
S82.1 Fracture of upper end of tibia	0.000	0.997	0.003
E85 Amyloidosis	0.000	0.997	0.003
V18 Pedal cyclist injured in noncollision transport accident	0.003	0.997	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.997	0.003
K91.5 Postcholecystectomy syndrome	0.000	0.997	0.003
N48.4 Impotence of organic origin	0.003	0.997	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.997	0.002
E73.8 Other lactose intolerance	0.000	0.997	0.002
E73.1 Secondary lactase deficiency	0.000	0.997	0.002
E73.0 Congenital lactase deficiency	0.000	0.997	0.002
K92.1 Melaena	0.003	0.997	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.997	0.002
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.997	0.000
K51.4 Pseudopolyposis of colon	0.003	0.997	0.000
M34.0 Progressive systemic sclerosis	0.000	0.997	0.003
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
R25.2 Cramp and spasm	0.000	0.997	0.003
H25.9 Senile cataract, unspecified	0.000	0.997	0.003
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.997	0.003
K92.9 Disease of digestive system, unspecified	0.000	0.997	0.002
V18.1 Passenger injured in nontraffic accident	0.002	0.997	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.997	0.002
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.997	0.002
E79.1 Lesch-Nyhan syndrome	0.000	0.997	0.002
L27.2 Dermatitis due to ingested food	0.000	0.997	0.002
Z99.1 Dependence on respirator	0.000	0.997	0.003
M22.3 Other derangements of patella	0.000	0.997	0.002
V18.5 Passenger injured in traffic accident	0.002	0.997	0.000
E70.3 Albinism	0.000	0.997	0.002
M31 Other necrotising vasculopathies	0.000	0.997	0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.001	0.997	0.002
E70.8 Other disorders of aromatic amino-acid metabolism	0.001	0.997	0.002
E70.2 Disorders of tyrosine metabolism	0.001	0.997	0.002
E70.1 Other hyperphenylalaninaemias	0.001	0.997	0.002
E70.0 Classical phenylketonuria	0.001	0.997	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.997	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations