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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2073723
log Bayes Factor = 56.7968
Chromosome 6   position 31,130,078  (GRCh37) Explore rs2073723 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E78.0 Pure hypercholesterolaemia
0.000 0.016 0.984
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.019 0.981
E70-E90 Metabolic disorders
0.000 0.024 0.976
G35 Multiple sclerosis
0.962 0.038 0.000
L40 Psoriasis
0.000 0.053 0.947
E14 Unspecified diabetes mellitus
0.000 0.067 0.933
L40.5 Arthropathic psoriasis
0.000 0.119 0.881
E11.0 With coma
0.000 0.123 0.877
E78.8 Other disorders of lipoprotein metabolism
0.000 0.138 0.862
E07 Other disorders of thyroid
0.000 0.156 0.844
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.165 0.835
E10.3 With ophthalmic complications
0.000 0.174 0.826
E14.3 With ophthalmic complications
0.000 0.174 0.826
E11.1 With ketoacidosis
0.000 0.189 0.811
E78.2 Mixed hyperlipidaemia
0.000 0.191 0.809
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.192 0.808
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.198 0.802
E03.8 Other specified hypothyroidism
0.000 0.200 0.800
L40.0 Psoriasis vulgaris
0.000 0.203 0.797
L40.8 Other psoriasis
0.000 0.209 0.791
E14.9 Without complications
0.000 0.217 0.783
E79 Disorders of purine and pyrimidine metabolism
0.000 0.238 0.762
E13 Other specified diabetes mellitus
0.000 0.241 0.759
E74 Other disorders of carbohydrate metabolism
0.000 0.244 0.756
E78.4 Other hyperlipidaemia
0.000 0.247 0.753
E10.6 With other specified complications
0.000 0.248 0.752
E10.8 With unspecified complications
0.000 0.252 0.748
E07.9 Disorder of thyroid, unspecified
0.000 0.256 0.744
K90 Intestinal malabsorption
0.000 0.260 0.740
E78.1 Pure hyperglyceridaemia
0.000 0.261 0.739
E14.5 With peripheral circulatory complications
0.000 0.265 0.735
E11.2 With renal complications
0.000 0.268 0.732
L40.1 Generalised pustular psoriasis
0.000 0.278 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E10.0 With coma
0.000 0.293 0.707
E78.3 Hyperchylomicronaemia
0.000 0.297 0.703
E78.6 Lipoprotein deficiency
0.000 0.297 0.703
E77 Disorders of glycoprotein metabolism
0.000 0.300 0.700
E76 Disorders of glycosaminoglycan metabolism
0.000 0.300 0.700
E72 Other disorders of amino-acid metabolism
0.000 0.300 0.700
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.300 0.700
E70 Disorders of aromatic amino-acid metabolism
0.000 0.300 0.700
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.300 0.700
E40-E46 Malnutrition
0.000 0.301 0.699
E10.1 With ketoacidosis
0.000 0.305 0.695
E78.5 Hyperlipidaemia, unspecified
0.000 0.306 0.694
E14.4 With neurological complications
0.000 0.306 0.693
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.311 0.689
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.317 0.683
L40.2 Acrodermatitis continua
0.000 0.321 0.679
G35-G37 Demyelinating diseases of the central nervous system
0.678 0.322 0.000
E84 Cystic fibrosis
0.000 0.327 0.673
L40.4 Guttate psoriasis
0.000 0.328 0.672
E14.6 With other specified complications
0.000 0.328 0.672
E16 Other disorders of pancreatic internal secretion
0.000 0.329 0.671
E14.1 With ketoacidosis
0.000 0.330 0.670
E14.7 With multiple complications
0.000 0.331 0.669
E14.0 With coma
0.000 0.331 0.669
E83 Disorders of mineral metabolism
0.627 0.338 0.035
E14.2 Withrenal complications
0.000 0.339 0.661
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.343 0.657
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.366 0.634
E03.1 Congenital hypothyroidism without goitre
0.000 0.367 0.633
E80.6 Other disorders of bilirubin metabolism
0.000 0.370 0.630
E14.8 With unspecified complications
0.000 0.373 0.627
E11.8 With unspecified complications
0.000 0.378 0.622
E05.8 Other thyrotoxicosis
0.000 0.379 0.621
E80.4 Gilbert's syndrome
0.000 0.388 0.612
E80.2 Other porphyria
0.000 0.389 0.611
E10.2 With renal complications
0.000 0.390 0.610
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.391 0.609
G37 Other demyelinating diseases of central nervous system
0.607 0.393 0.000
E13.9 Without complications
0.000 0.393 0.607
E07.1 Dyshormogenetic goitre
0.000 0.395 0.605
E07.0 Hypersecretion of calcitonin
0.000 0.395 0.605
E10.5 With peripheral circulatory complications
0.000 0.401 0.599
K90.9 Intestinal malabsorption, unspecified
0.000 0.402 0.598
E88 Other metabolic disorders
0.000 0.408 0.592
E15 Nondiabetic hypoglycaemic coma
0.000 0.420 0.579
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.425 0.575
E80.5 Crigler-Najjar syndrome
0.000 0.425 0.575
E80.3 Defects of catalase and peroxydase
0.000 0.425 0.575
E80.0 Hereditary erythropoietic porphyria
0.000 0.425 0.575
E07.8 Other specified disorders of thyroid
0.000 0.426 0.573
L40-L45 Papulosquamous disorders
0.000 0.428 0.572
E80.1 Porphyria cutanea tarda
0.000 0.430 0.569
E73 Lactose intolerance
0.000 0.437 0.562
E11.5 With peripheral circulatory complications
0.000 0.442 0.558
L40.3 Pustulosis palmaris et plantaris
0.000 0.444 0.555
E83.3 Disorders of phosphorus metabolism
0.541 0.449 0.010
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.453 0.547
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.453 0.547
E79.1 Lesch-Nyhan syndrome
0.000 0.453 0.547
E13.8 With unspecified complications
0.000 0.455 0.544
E13.7 With multiple complications
0.000 0.455 0.544
E13.6 With other specified complications
0.000 0.455 0.544
E13.5 With peripheral circulatory complications
0.000 0.455 0.544
E13.4 With neurological complications
0.000 0.455 0.544
E13.2 With renal complications
0.000 0.455 0.544
E13.1 With ketoacidosis
0.000 0.455 0.544
E13.0 With coma
0.000 0.455 0.544
E16.2 Hypoglycaemia, unspecified
0.000 0.457 0.543
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.458 0.542
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.458 0.542
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.458 0.542
E74.2 Disorders of galactose metabolism
0.000 0.458 0.542
E74.1 Disorders of fructose metabolism
0.000 0.458 0.542
G37.9 Demyelinating disease of central nervous system, unspecified
0.539 0.461 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.469 0.531
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.469 0.531
K90.1 Tropical sprue
0.000 0.469 0.531
K90.8 Other intestinal malabsorption
0.000 0.471 0.529
E16.1 Other hypoglycaemia
0.000 0.478 0.522
G36 Other acute disseminated demyelination
0.521 0.479 0.000
E13.3 With ophthalmic complications
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.487 0.513
E83.9 Disorder of mineral metabolism, unspecified
0.486 0.491 0.022
C83.3 Large cell (diffuse)
0.000 0.495 0.505
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.498 0.502
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.498 0.502
E70.3 Albinism
0.000 0.498 0.502
E70.2 Disorders of tyrosine metabolism
0.000 0.498 0.502
E70.1 Other hyperphenylalaninaemias
0.000 0.498 0.502
E70.0 Classical phenylketonuria
0.000 0.498 0.502
E71.3 Disorders of fatty-acid metabolism
0.000 0.498 0.502
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.498 0.502
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.498 0.502
E71.0 Maple-syrup-urine disease
0.000 0.498 0.502
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.498 0.502
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.498 0.502
E72.5 Disorders of glycine metabolism
0.000 0.498 0.502
E72.4 Disorders of ornithine metabolism
0.000 0.498 0.502
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.498 0.502
E72.2 Disorders of urea cycle metabolism
0.000 0.498 0.502
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.498 0.502
E72.0 Disorders of amino-acid transport
0.000 0.498 0.502
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.498 0.502
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.498 0.502
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.498 0.502
E76.2 Other mucopolysaccharidoses
0.000 0.498 0.502
E76.1 Mucopolysaccharidosis, type II
0.000 0.498 0.502
E76.0 Mucopolysaccharidosis, type I
0.000 0.498 0.502
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.498 0.502
E77.8 Other disorders of glycoprotein metabolism
0.000 0.498 0.502
E77.1 Defects in glycoprotein degradation
0.000 0.498 0.502
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.498 0.502
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.499 0.501
E45 Retarded development following protein-energy malnutrition
0.000 0.499 0.501
E43 Unspecified severe protein-energy malnutrition
0.000 0.499 0.501
E42 Marasmic kwashiorkor
0.000 0.499 0.501
E41 Nutritional marasmus
0.000 0.499 0.501
E40 Kwashiorkor
0.000 0.499 0.501
E10.4 With neurological complications
0.000 0.502 0.498
G37.8 Other specified demyelinating diseases of central nervous system
0.490 0.510 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.510 0.489
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.510 0.489
E75.3 Sphingolipidosis, unspecified
0.000 0.510 0.489
E75.2 Other sphingolipidosis
0.000 0.510 0.489
E75.1 Other gangliosidosis
0.000 0.510 0.489
E75.0 GM2 gangliosidosis
0.000 0.510 0.489
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.516 0.484
E46 Unspecified protein-energy malnutrition
0.000 0.517 0.483
E84.8 Cystic fibrosis with other manifestations
0.000 0.517 0.482
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.517 0.482
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.517 0.482
E74.0 Glycogen storage disease
0.000 0.518 0.481
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.519 0.481
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.519 0.481
E16.4 Abnormal secretion of gastrin
0.000 0.519 0.481
E16.3 Increased secretion of glucagon
0.000 0.519 0.481
L43 Lichen planus
0.000 0.525 0.475
E83.8 Other disorders of mineral metabolism
0.450 0.525 0.025
E83.2 Disorders of zinc metabolism
0.450 0.525 0.025
E83.0 Disorders of copper metabolism
0.450 0.525 0.025
E11.6 With other specified complications
0.000 0.526 0.473
E75.5 Other lipid storage disorders
0.000 0.527 0.473
E88.2 Lipomatosis, not elsewhere classified
0.000 0.538 0.462
E84.9 Cystic fibrosis, unspecified
0.000 0.544 0.456
L42 Pityriasis rosea
0.000 0.555 0.445
G37.5 Concentric sclerosis [Balo]
0.435 0.564 0.000
G37.4 Subacute necrotising myelitis
0.435 0.564 0.000
G37.2 Central pontine myelinolysis
0.435 0.564 0.000
G37.1 Central demyelination of corpus callosum
0.435 0.564 0.000
G37.0 Diffuse sclerosis
0.435 0.564 0.000
E11.4 With neurological complications
0.000 0.567 0.433
L43.9 Lichen planus, unspecified
0.000 0.570 0.430
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.571 0.428
E88.9 Metabolic disorder, unspecified
0.000 0.575 0.425
E88.8 Other specified metabolic disorders
0.000 0.575 0.425
E85 Amyloidosis
0.001 0.575 0.424
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.580 0.420
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.419 0.581 0.000
E88.3 Tumour lysis syndrome
0.000 0.581 0.419
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.590 0.410
L44 Other papulosquamous disorders
0.000 0.590 0.410
L41 Parapsoriasis
0.000 0.590 0.410
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.590 0.410
G36.0 Neuromyelitis optica [Devic]
0.409 0.591 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.593 0.407
E73.8 Other lactose intolerance
0.000 0.597 0.403
E73.1 Secondary lactase deficiency
0.000 0.597 0.403
E73.0 Congenital lactase deficiency
0.000 0.597 0.403
E89.4 Postprocedural ovarian failure
0.000 0.610 0.390
E20-E35 Disorders of other endocrine glands
0.000 0.614 0.386
E06 Thyroiditis
0.000 0.619 0.381
G36.9 Acute disseminated demyelination, unspecified
0.374 0.626 0.000
G36.8 Other specified acute disseminated demyelination
0.374 0.626 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.374 0.626 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.632 0.368
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.632 0.368
E89.5 Postprocedural testicular hypofunction
0.000 0.632 0.368
E89.1 Postprocedural hypoinsulinaemia
0.000 0.632 0.368
E44.1 Mild protein-energy malnutrition
0.000 0.640 0.359
E44.0 Moderate protein-energy malnutrition
0.000 0.640 0.359
E83.4 Disorders of magnesium metabolism
0.346 0.642 0.012
E89.3 Postprocedural hypopituitarism
0.000 0.650 0.350
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.652 0.347
E28 Ovarian dysfunction
0.000 0.654 0.346
L43.3 Subacute (active) lichen planus
0.000 0.659 0.341
L43.2 Lichenoid drug reaction
0.000 0.659 0.341
L43.1 Bullous lichen planus
0.000 0.659 0.341
L43.0 Hypertrophic lichen planus
0.000 0.659 0.341
E28.2 Polycystic ovarian syndrome
0.000 0.674 0.326
E65-E68 Obesity and other hyperalimentation
0.000 0.674 0.325
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.676 0.324
M06.9 Rheumatoid arthritis, unspecified
0.000 0.680 0.320
C83 Diffuse non-Hodgkin's lymphoma
0.005 0.680 0.314
E23 Hypofunction and other disorders of pituitary gland
0.000 0.685 0.315
E24 Cushing's syndrome
0.000 0.691 0.309
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.001 0.692 0.307
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.695 0.304
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.695 0.304
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.695 0.304
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.698 0.302
C85.1 B-cell lymphoma, unspecified
0.000 0.699 0.301
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.007 0.700 0.293
E89.2 Postprocedural hypoparathyroidism
0.000 0.700 0.300
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.702 0.298
L41.9 Parapsoriasis, unspecified
0.000 0.706 0.294
L41.8 Other parapsoriasis
0.000 0.706 0.294
L41.5 Retiform parapsoriasis
0.000 0.706 0.294
L41.4 Large plaque parapsoriasis
0.000 0.706 0.294
L41.3 Small plaque parapsoriasis
0.000 0.706 0.294
L41.2 Lymphomatoid papulosis
0.000 0.706 0.294
L41.1 Pityriasis lichenoides chronica
0.000 0.706 0.294
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.706 0.294
L44.9 Papulosquamous disorder, unspecified
0.000 0.706 0.294
L44.8 Other specified papulosquamous disorders
0.000 0.706 0.294
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.706 0.294
L44.3 Lichen ruber moniliformis
0.000 0.706 0.294
L44.2 Lichen striatus
0.000 0.706 0.294
L44.1 Lichen nitidus
0.000 0.706 0.294
L44.0 Pityriasis rubra pilaris
0.000 0.706 0.294
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.710 0.290
E85.8 Other amyloidosis
0.001 0.711 0.289
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.712 0.288
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.002 0.713 0.285
E85.9 Amyloidosis, unspecified
0.001 0.717 0.283
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.718 0.282
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.722 0.278
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.723 0.277
E32 Diseases of thymus
0.000 0.723 0.277
E31 Polyglandular dysfunction
0.000 0.723 0.277
E30 Disorders of puberty, not elsewhere classified
0.000 0.723 0.277
E25 Adrenogenital disorders
0.000 0.723 0.277
E50-E64 Other nutritional deficiencies
0.000 0.725 0.275
E06.5 Other chronic thyroiditis
0.000 0.726 0.273
E06.4 Drug-induced thyroiditis
0.000 0.726 0.273
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.726 0.273
E06.0 Acute thyroiditis
0.000 0.726 0.273
L43.8 Other lichen planus
0.000 0.730 0.270
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.731 0.269
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.731 0.269
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.731 0.269
E73.9 Lactose intolerance, unspecified
0.001 0.734 0.266
E06.1 Subacute thyroiditis
0.001 0.740 0.259
E26 Hyperaldosteronism
0.000 0.742 0.258
E23.7 Disorder of pituitary gland, unspecified
0.000 0.744 0.256
E21.3 Hyperparathyroidism, unspecified
0.000 0.747 0.253
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.747 0.253
E83.5 Disorders of calcium metabolism
0.245 0.750 0.005
E28.9 Ovarian dysfunction, unspecified
0.000 0.752 0.248
E28.8 Other ovarian dysfunction
0.000 0.752 0.248
E28.1 Androgen excess
0.000 0.752 0.248
E28.0 Oestrogen excess
0.000 0.752 0.248
E23.2 Diabetes insipidus
0.000 0.753 0.247
E24.2 Drug-induced Cushing's syndrome
0.000 0.753 0.246
C83.7 Burkitt's tumour
0.003 0.754 0.242
E85.4 Organ-limited amyloidosis
0.001 0.756 0.243
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.761 0.239
E67 Other hyperalimentation
0.000 0.766 0.233
E68 Sequelae of hyperalimentation
0.000 0.766 0.233
E24.9 Cushing's syndrome, unspecified
0.000 0.768 0.232
E23.6 Other disorders of pituitary gland
0.000 0.768 0.231
C82.2 Large cell, follicular
0.001 0.769 0.230
C83.6 Undifferentiated (diffuse)
0.004 0.771 0.226
C83.5 Lymphoblastic (diffuse)
0.004 0.771 0.226
C83.4 Immunoblastic (diffuse)
0.004 0.771 0.226
C83.2 Mixed small and large cell (diffuse)
0.004 0.771 0.226
E85.3 Secondary systemic amyloidosis
0.001 0.773 0.227
E20 Hypoparathyroidism
0.000 0.773 0.226
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.774 0.226
E23.1 Drug-induced hypopituitarism
0.000 0.774 0.226
C82.3 Follicular lymphoma grade IIIa
0.002 0.778 0.220
E24.8 Other Cushing's syndrome
0.000 0.778 0.222
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.778 0.222
E24.3 Ectopic ACTH syndrome
0.000 0.778 0.222
E24.1 Nelson's syndrome
0.000 0.778 0.222
E24.0 Pituitary-dependent Cushing's disease
0.000 0.778 0.222
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.001 0.779 0.220
C85.0 Lymphosarcoma
0.001 0.779 0.220
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.004 0.779 0.217
E11.3 With ophthalmic complications
0.000 0.780 0.220
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.781 0.219
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.782 0.218
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.005 0.785 0.210
C86 Other specified types of T/NK-cell lymphoma
0.005 0.785 0.210
C81 Hodgkin's disease
0.004 0.785 0.211
C85.7 Other specified types of non-Hodgkin's lymphoma
0.001 0.788 0.212
C84 Peripheral and cutaneous T-cell lymphomas
0.004 0.789 0.207
E29 Testicular dysfunction
0.000 0.789 0.211
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.789 0.211
E22 Hyperfunction of pituitary gland
0.000 0.791 0.209
E23.0 Hypopituitarism
0.000 0.791 0.208
E21.4 Other specified disorders of parathyroid gland
0.000 0.793 0.207
E21.2 Other hyperparathyroidism
0.000 0.793 0.207
C82.6 Cutaneous follicle centre lymphoma
0.002 0.794 0.204
C82.5 Diffuse follicle centre lymphoma
0.002 0.794 0.204
E28.3 Primary ovarian failure
0.000 0.799 0.201
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.002 0.800 0.199
E25.9 Adrenogenital disorder, unspecified
0.000 0.801 0.199
E25.8 Other adrenogenital disorders
0.000 0.801 0.199
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.801 0.199
E30.9 Disorder of puberty, unspecified
0.000 0.801 0.199
E30.8 Other disorders of puberty
0.000 0.801 0.199
E30.1 Precocious puberty
0.000 0.801 0.199
E30.0 Delayed puberty
0.000 0.801 0.199
E31.9 Polyglandular dysfunction, unspecified
0.000 0.801 0.199
E31.8 Other polyglandular dysfunction
0.000 0.801 0.199
E31.1 Polyglandular hyperfunction
0.000 0.801 0.199
E31.0 Autoimmune polyglandular failure
0.000 0.801 0.199
E32.9 Disease of thymus, unspecified
0.000 0.801 0.199
E32.8 Other diseases of thymus
0.000 0.801 0.199
E32.1 Abscess of thymus
0.000 0.801 0.199
E32.0 Persistent hyperplasia of thymus
0.000 0.801 0.199
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.801 0.199
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.801 0.199
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.801 0.199
C94 Other leukaemias of specified cell type
0.006 0.802 0.192
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.803 0.197
E63 Other nutritional deficiencies
0.000 0.803 0.197
E50 Vitamin A deficiency
0.000 0.803 0.197
E60 Dietary zinc deficiency
0.000 0.803 0.197
E59 Dietary selenium deficiency
0.000 0.803 0.197
E54 Ascorbic acid deficiency
0.000 0.803 0.197
E52 Niacin deficiency [pellagra]
0.000 0.803 0.197
C82.0 Small cleaved cell, follicular
0.002 0.804 0.194
E56 Other vitamin deficiencies
0.000 0.807 0.193
C82.4 Follicular lymphoma grade IIIb
0.002 0.809 0.189
E58 Dietary calcium deficiency
0.000 0.810 0.190
E26.9 Hyperaldosteronism, unspecified
0.000 0.815 0.185
E26.8 Other hyperaldosteronism
0.000 0.815 0.185
E26.1 Secondary hyperaldosteronism
0.000 0.815 0.185
E51 Thiamine deficiency
0.000 0.816 0.184
C93 Monocytic leukaemia
0.006 0.816 0.178
C83.1 Small cleaved cell (diffuse)
0.004 0.817 0.179
E61 Deficiency of other nutrient elements
0.000 0.819 0.181
C81.9 Hodgkin's disease, unspecified
0.001 0.819 0.180
E06.3 Autoimmune thyroiditis
0.000 0.819 0.180
E06.9 Thyroiditis, unspecified
0.001 0.830 0.169
C88 Malignant immunoproliferative diseases
0.006 0.831 0.163
E65 Localised adiposity
0.000 0.831 0.168
E67.8 Other specified hyperalimentation
0.000 0.832 0.167
E67.3 Hypervitaminosis D
0.000 0.832 0.167
E67.2 Megavitamin-B6 syndrome
0.000 0.832 0.167
E67.1 Hypercarotenaemia
0.000 0.832 0.167
E67.0 Hypervitaminosis A
0.000 0.832 0.167
E26.0 Primary hyperaldosteronism
0.000 0.833 0.167
C91 Lymphoid leukaemia
0.004 0.834 0.162
E20.8 Other hypoparathyroidism
0.000 0.837 0.162
E20.1 Pseudohypoparathyroidism
0.000 0.837 0.162
E20.0 Idiopathic hypoparathyroidism
0.000 0.837 0.162
C84.5 Other and unspecified T-cell lymphomas
0.003 0.844 0.154
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.003 0.845 0.152
C81.3 Lymphocytic depletion
0.003 0.845 0.152
C81.2 Mixed cellularity
0.003 0.845 0.152
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.004 0.845 0.151
C86.5 Angioimmunoblastic T-cell lymphoma
0.004 0.845 0.151
C86.4 Blastic NK-cell lymphoma
0.004 0.845 0.151
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.004 0.845 0.151
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.004 0.845 0.151
C86.1 Hepatosplenic T-cell lymphoma
0.004 0.845 0.151
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.004 0.845 0.151
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.004 0.845 0.151
C96.8 Histiocytic sarcoma
0.004 0.845 0.151
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.004 0.845 0.151
C96.6 Unifocal Langerhans-cell histiocytosis
0.004 0.845 0.151
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.004 0.845 0.151
C96.4 Sarcoma of dendritic cells (accessory cells)
0.004 0.845 0.151
C96.3 True histiocytic lymphoma
0.004 0.845 0.151
C96.2 Malignant mast cell tumour
0.004 0.845 0.151
C96.1 Malignant histiocytosis
0.004 0.845 0.151
C96.0 Letterer-Siwe disease
0.004 0.845 0.151
C81.7 Other Hodgkin's disease
0.003 0.847 0.150
C84.9 Mature T/NK-cell lymphoma, unspecified
0.003 0.848 0.149
C84.8 Cutaneous T-cell lymphoma, unspecified
0.003 0.848 0.149
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.003 0.848 0.149
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.003 0.848 0.149
C84.3 Lymphoepithelioid lymphoma
0.003 0.848 0.149
C84.2 T-zone lymphoma
0.003 0.848 0.149
C84.1 Sezary's diease
0.003 0.848 0.149
E29.9 Testicular dysfunction, unspecified
0.000 0.848 0.151
E29.8 Other testicular dysfunction
0.000 0.848 0.151
E29.0 Testicular hyperfunction
0.000 0.848 0.151
C84.0 Mycosis fungoides
0.003 0.848 0.149
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.850 0.150
E22.8 Other hyperfunction of pituitary gland
0.000 0.850 0.150
E22.1 Hyperprolactinaemia
0.000 0.851 0.148
C81.0 Lymphocytic predominance
0.003 0.851 0.146
C82.1 Mixed small cleaved and large cell, follicular
0.002 0.853 0.145
C91.9 Lymphoid leukaemia, unspecified
0.002 0.853 0.145
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.853 0.146
E89.0 Postprocedural hypothyroidism
0.000 0.856 0.144
C95 Leukaemia of unspecified cell type
0.007 0.856 0.137
C84.4 Peripheral T-cell lymphoma
0.003 0.857 0.140
C94.7 Other specified leukaemias
0.004 0.858 0.138
C94.5 Acute myelofibrosis
0.004 0.858 0.138
C94.4 Acute panmyelosis
0.004 0.858 0.138
C94.3 Mast cell leukaemia
0.004 0.858 0.138
C94.2 Acute megakaryoblastic leukaemia
0.004 0.858 0.138
C94.1 Chronic erythraemia
0.004 0.858 0.138
C94.0 Acute erythraemia and erythroleukaemia
0.004 0.858 0.138
E50.9 Vitamin A deficiency, unspecified
0.000 0.858 0.141
E50.8 Other manifestations of vitamin A deficiency
0.000 0.858 0.141
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.858 0.141
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.858 0.141
E50.5 Vitamin A deficiency with night blindness
0.000 0.858 0.141
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.858 0.141
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.858 0.141
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.858 0.141
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.858 0.141
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.858 0.141
E63.9 Nutritional deficiency, unspecified
0.000 0.858 0.141
E63.8 Other specified nutritional deficiencies
0.000 0.858 0.141
E63.1 Imbalance of constituents of food intake
0.000 0.858 0.141
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.858 0.141
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.858 0.141
E64.8 Sequelae of other nutritional deficiencies
0.000 0.858 0.141
E64.3 Sequelae of rickets
0.000 0.858 0.141
E64.2 Sequelae of vitamin C deficiency
0.000 0.858 0.141
E64.1 Sequelae of vitamin A deficiency
0.000 0.858 0.141
E64.0 Sequelae of protein-energy malnutrition
0.000 0.858 0.141
M06 Other rheumatoid arthritis
0.000 0.859 0.141
E55 Vitamin D deficiency
0.000 0.860 0.140
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.861 0.139
E56.9 Vitamin deficiency, unspecified
0.000 0.861 0.138

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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