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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2074478
log Bayes Factor = 42.0592
Chromosome 6   position 31,105,633  (GRCh37) Explore rs2074478 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.003 0.997
E11 Non-insulin-dependent diabetes mellitus
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.004 0.996
G35 Multiple sclerosis
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
E78.2 Mixed hyperlipidaemia
0.000 0.010 0.990
E14 Unspecified diabetes mellitus
0.000 0.015 0.985
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.016 0.984
E11.9 Without complications
0.000 0.025 0.975
E14.9 Without complications
0.000 0.030 0.970
L40 Psoriasis
0.000 0.040 0.960
E10.4 With neurological complications
0.000 0.047 0.953
E10.2 With renal complications
0.000 0.050 0.950
I21.9 Acute myocardial infarction, unspecified
0.000 0.053 0.947
E05.9 Thyrotoxicosis, unspecified
0.000 0.054 0.946
I21 Acute myocardial infarction
0.000 0.055 0.945
L40.5 Arthropathic psoriasis
0.000 0.055 0.945
I20-I25 Ischaemic heart diseases
0.000 0.059 0.941
I22 Subsequent myocardial infarction
0.000 0.068 0.932
G35-G37 Demyelinating diseases of the central nervous system
0.923 0.077 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.086 0.914
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.109 0.891
E10.0 With coma
0.000 0.111 0.889
I24 Other acute ischaemic heart diseases
0.000 0.115 0.885
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.124 0.876
E16.1 Other hypoglycaemia
0.000 0.136 0.864
E85 Amyloidosis
0.000 0.138 0.862
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.140 0.860
E10.8 With unspecified complications
0.000 0.146 0.854
E11.0 With coma
0.000 0.150 0.850
E78.8 Other disorders of lipoprotein metabolism
0.000 0.154 0.846
E10.5 With peripheral circulatory complications
0.000 0.157 0.843
K51 Ulcerative colitis
0.840 0.160 0.000
E11.6 With other specified complications
0.000 0.160 0.840
E11.1 With ketoacidosis
0.000 0.169 0.831
Chapter VI Diseases of the nervous system
0.830 0.170 0.000
E11.5 With peripheral circulatory complications
0.000 0.170 0.830
K51.9 Ulcerative colitis, unspecified
0.824 0.176 0.000
E11.2 With renal complications
0.000 0.184 0.816
K51.3 Ulcerative (chronic) rectosigmoiditis
0.815 0.185 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.185 0.815
E74 Other disorders of carbohydrate metabolism
0.000 0.189 0.811
K51.8 Other ulcerative colitis
0.807 0.193 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.194 0.806
G30-G32 Other degenerative diseases of the nervous system
0.794 0.205 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.793 0.207 0.000
I25 Chronic ischaemic heart disease
0.000 0.210 0.790
E14.3 With ophthalmic complications
0.000 0.218 0.782
L40.0 Psoriasis vulgaris
0.000 0.221 0.779
E13 Other specified diabetes mellitus
0.000 0.227 0.773
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.229 0.771
K51.4 Pseudopolyposis of colon
0.766 0.234 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.235 0.765
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.763 0.237 0.000
G37 Other demyelinating diseases of central nervous system
0.761 0.239 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.754 0.246 0.000
E10.6 With other specified complications
0.000 0.247 0.753
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.253 0.747
E85.9 Amyloidosis, unspecified
0.000 0.267 0.733
K51.5 Mucosal proctocolitis
0.731 0.269 0.000
E14.4 With neurological complications
0.000 0.270 0.730
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.277 0.723
E05.8 Other thyrotoxicosis
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.3 With ophthalmic complications
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.716
E78.3 Hyperchylomicronaemia
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E84 Cystic fibrosis
0.000 0.284 0.716
E79 Disorders of purine and pyrimidine metabolism
0.000 0.284 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E72 Other disorders of amino-acid metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E70 Disorders of aromatic amino-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
G80-G83 Cerebral palsy and other paralytic syndromes
0.715 0.285 0.000
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E03.1 Congenital hypothyroidism without goitre
0.000 0.285 0.715
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E11.7 With multiple complications
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.713
E16.3 Increased secretion of glucagon
0.000 0.286 0.713
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.288 0.712
E86 Volume depletion
0.000 0.292 0.708
E14.8 With unspecified complications
0.000 0.293 0.706
E14.7 With multiple complications
0.000 0.293 0.706
E14.6 With other specified complications
0.000 0.293 0.706
E14.2 Withrenal complications
0.000 0.293 0.706
E14.1 With ketoacidosis
0.000 0.293 0.706
E14.0 With coma
0.000 0.293 0.706
E05.5 Thyroid crisis or storm
0.000 0.294 0.706
E05.4 Thyrotoxicosis factitia
0.000 0.294 0.706
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.294 0.706
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.294 0.706
K51.0 Ulcerative (chronic) enterocolitis
0.706 0.294 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.297 0.703
G20-G26 Extrapyramidal and movement disorders
0.700 0.300 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.306 0.694
E14.5 With peripheral circulatory complications
0.000 0.309 0.691
E73 Lactose intolerance
0.000 0.310 0.690
L40.4 Guttate psoriasis
0.000 0.312 0.688
L40.2 Acrodermatitis continua
0.000 0.312 0.688
G36 Other acute disseminated demyelination
0.686 0.314 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.316 0.683
I23 Certain current complications following acute myocardial infarction
0.000 0.317 0.683
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.322 0.678
E07 Other disorders of thyroid
0.000 0.322 0.678
E85.4 Organ-limited amyloidosis
0.000 0.323 0.677
L40.1 Generalised pustular psoriasis
0.000 0.324 0.676
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.324 0.676
L40.8 Other psoriasis
0.000 0.325 0.675
I20 Angina pectoris
0.000 0.328 0.672
G37.8 Other specified demyelinating diseases of central nervous system
0.671 0.329 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.331 0.669
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.332 0.668
G04 Encephalitis, myelitis and encephalomyelitis
0.668 0.332 0.000
E13.9 Without complications
0.000 0.336 0.664
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.663 0.337 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.339 0.661
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.341 0.659
E78.4 Other hyperlipidaemia
0.000 0.341 0.659
I20.0 Unstable angina
0.000 0.342 0.658
G03 Meningitis due to other and unspecified causes
0.655 0.345 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.347 0.653
G83 Other paralytic syndromes
0.651 0.349 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.351 0.649
E88 Other metabolic disorders
0.000 0.353 0.647
I25.2 Old myocardial infarction
0.000 0.358 0.642
K51.2 Ulcerative (chronic) proctitis
0.635 0.365 0.000
K50-K52 Noninfective enteritis and colitis
0.635 0.365 0.000
E11.4 With neurological complications
0.000 0.368 0.632
I22.8 Subsequent myocardial infarction of other sites
0.000 0.371 0.629
G00 Bacterial meningitis, not elsewhere classified
0.626 0.374 0.000
G90-G99 Other disorders of the nervous system
0.624 0.376 0.000
K50 Crohn's disease [regional enteritis]
0.623 0.377 0.000
E85.8 Other amyloidosis
0.000 0.382 0.618
E85.3 Secondary systemic amyloidosis
0.000 0.382 0.618
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.382 0.618
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.382 0.618
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.382 0.618
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.382 0.618
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.613 0.387 0.000
G30 Alzheimer's disease
0.610 0.390 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.608 0.391 0.000
I24.1 Dressler's syndrome
0.000 0.392 0.608
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.393 0.607
I25.1 Atherosclerotic heart disease
0.000 0.394 0.606
L40.3 Pustulosis palmaris et plantaris
0.000 0.397 0.603
G24 Dystonia
0.600 0.400 0.000
G91 Hydrocephalus
0.599 0.401 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.593 0.407 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.410 0.590
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.414 0.586
G80 Infantile cerebral palsy
0.586 0.414 0.000
E21.0 Primary hyperparathyroidism
0.000 0.416 0.584
G11 Hereditary ataxia
0.583 0.417 0.000
G70-G73 Diseases of myoneural junction and muscle
0.582 0.418 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.418 0.581
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.418 0.581
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.418 0.581
E74.2 Disorders of galactose metabolism
0.000 0.418 0.581
E74.1 Disorders of fructose metabolism
0.000 0.418 0.581
E74.0 Glycogen storage disease
0.000 0.418 0.581
E40-E46 Malnutrition
0.000 0.420 0.580
G31.2 Degeneration of nervous system due to alcohol
0.575 0.425 0.000
E06 Thyroiditis
0.000 0.427 0.573
E11.8 With unspecified complications
0.000 0.427 0.573
G37.9 Demyelinating disease of central nervous system, unspecified
0.573 0.427 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.573 0.427 0.000
K50.9 Crohn's disease, unspecified
0.570 0.430 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.570 0.430 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.570 0.430 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.569 0.431 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.432 0.568
K50.1 Crohn's disease of large intestine
0.567 0.433 0.000
I25.6 Silent myocardial ischaemia
0.000 0.433 0.566
G91.1 Obstructive hydrocephalus
0.563 0.437 0.000
G83.1 Monoplegia of lower limb
0.559 0.440 0.000
G03.9 Meningitis, unspecified
0.556 0.444 0.000
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
I25.3 Aneurysm of heart
0.000 0.450 0.550
G20 Parkinson's disease
0.550 0.450 0.000
G83.4 Cauda equina syndrome
0.548 0.452 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.547 0.453 0.000
G37.5 Concentric sclerosis [Balo]
0.546 0.454 0.000
G37.4 Subacute necrotising myelitis
0.546 0.454 0.000
G37.2 Central pontine myelinolysis
0.546 0.454 0.000
G37.1 Central demyelination of corpus callosum
0.546 0.454 0.000
G37.0 Diffuse sclerosis
0.546 0.454 0.000
K50.0 Crohn's disease of small intestine
0.540 0.460 0.000
G83.9 Paralytic syndrome, unspecified
0.539 0.461 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.538 0.462 0.000
G24.9 Dystonia, unspecified
0.538 0.462 0.000
G10 Huntington's disease
0.532 0.468 0.000
G82 Paraplegia and tetraplegia
0.526 0.474 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.474 0.526
G01 Meningitis in bacterial diseases classified elsewhere
0.525 0.475 0.000
E22 Hyperfunction of pituitary gland
0.000 0.475 0.525
E23 Hypofunction and other disorders of pituitary gland
0.000 0.477 0.523
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.477 0.523
G36.0 Neuromyelitis optica [Devic]
0.517 0.483 0.000
G91.9 Hydrocephalus, unspecified
0.516 0.484 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.486 0.513
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.486 0.513
E70.3 Albinism
0.000 0.486 0.513
E70.2 Disorders of tyrosine metabolism
0.000 0.486 0.513
E70.1 Other hyperphenylalaninaemias
0.000 0.486 0.513
E70.0 Classical phenylketonuria
0.000 0.486 0.513
E71.3 Disorders of fatty-acid metabolism
0.000 0.486 0.513
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.486 0.513
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.486 0.513
E71.0 Maple-syrup-urine disease
0.000 0.486 0.513
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.486 0.513
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.486 0.513
E72.5 Disorders of glycine metabolism
0.000 0.486 0.513
E72.4 Disorders of ornithine metabolism
0.000 0.486 0.513
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.486 0.513
E72.2 Disorders of urea cycle metabolism
0.000 0.486 0.513
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.486 0.513
E72.0 Disorders of amino-acid transport
0.000 0.486 0.513
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.486 0.513
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.486 0.513
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.486 0.513
E76.2 Other mucopolysaccharidoses
0.000 0.486 0.513
E76.1 Mucopolysaccharidosis, type II
0.000 0.486 0.513
E76.0 Mucopolysaccharidosis, type I
0.000 0.486 0.513
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.486 0.513
E77.8 Other disorders of glycoprotein metabolism
0.000 0.486 0.513
E77.1 Defects in glycoprotein degradation
0.000 0.486 0.513
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.486 0.513
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.486 0.513
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.486 0.513
E79.1 Lesch-Nyhan syndrome
0.000 0.486 0.513
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.486 0.513
E84.9 Cystic fibrosis, unspecified
0.000 0.486 0.513
E84.8 Cystic fibrosis with other manifestations
0.000 0.486 0.513
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.486 0.513
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.486 0.513
G30.0 Alzheimer's disease with early onset
0.511 0.489 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.490 0.510
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.490 0.510
E89.5 Postprocedural testicular hypofunction
0.000 0.490 0.510
E89.1 Postprocedural hypoinsulinaemia
0.000 0.490 0.510
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.492 0.508
G11.4 Hereditary spastic paraplegia
0.505 0.495 0.000
E83 Disorders of mineral metabolism
0.249 0.497 0.254
G23 Other degenerative diseases of basal ganglia
0.502 0.498 0.000
G21 Secondary Parkinsonism
0.502 0.498 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.502 0.498 0.000
G22 Parkinsonism in diseases classified elsewhere
0.502 0.498 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.499 0.501 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.502 0.498
E89.4 Postprocedural ovarian failure
0.000 0.502 0.498
G93 Other disorders of brain
0.497 0.503 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.504 0.496
E73.8 Other lactose intolerance
0.000 0.505 0.495
E73.1 Secondary lactase deficiency
0.000 0.505 0.495
E73.0 Congenital lactase deficiency
0.000 0.505 0.495
G00.9 Bacterial meningitis, unspecified
0.494 0.506 0.000
G36.9 Acute disseminated demyelination, unspecified
0.492 0.508 0.000
G36.8 Other specified acute disseminated demyelination
0.492 0.508 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.492 0.508 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.490 0.509 0.000
G14 Postpolio syndrome
0.490 0.509 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.510 0.490
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.510 0.490
E75.3 Sphingolipidosis, unspecified
0.000 0.510 0.490
E75.2 Other sphingolipidosis
0.000 0.510 0.490
E75.1 Other gangliosidosis
0.000 0.510 0.490
E75.0 GM2 gangliosidosis
0.000 0.510 0.490
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.510 0.490
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.510 0.490
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.489 0.511 0.000
G91.0 Communicating hydrocephalus
0.488 0.512 0.000
G31.0 Circumscribed brain atrophy
0.486 0.514 0.000
E24 Cushing's syndrome
0.000 0.514 0.486
E07.1 Dyshormogenetic goitre
0.000 0.514 0.486
E07.0 Hypersecretion of calcitonin
0.000 0.514 0.486
G30.8 Other Alzheimer's disease
0.482 0.518 0.000
G82.1 Spastic paraplegia
0.481 0.519 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.479 0.521 0.000
G04.1 Tropical spastic paraplegia
0.479 0.521 0.000
G04.0 Acute disseminated encephalitis
0.479 0.521 0.000
G80.8 Other infantile cerebral palsy
0.478 0.522 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.476 0.524 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.476 0.524 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.476 0.524 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.476 0.524 0.000
E07.8 Other specified disorders of thyroid
0.000 0.525 0.475
G03.8 Meningitis due to other specified causes
0.469 0.530 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.469 0.530 0.000
G03.1 Chronic meningitis
0.469 0.530 0.000
G03.0 Nonpyogenic meningitis
0.469 0.530 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.531 0.469
E21.3 Hyperparathyroidism, unspecified
0.000 0.531 0.469
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.532 0.468
E32 Diseases of thymus
0.000 0.532 0.468
E30 Disorders of puberty, not elsewhere classified
0.000 0.532 0.468
E25 Adrenogenital disorders
0.000 0.532 0.468
G83.5 Locked-in syndrome
0.467 0.533 0.000
G83.3 Monoplegia, unspecified
0.467 0.533 0.000
G83.0 Diplegia of upper limbs
0.467 0.533 0.000
G00.1 Pneumococcal meningitis
0.466 0.534 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.536 0.464
G06.2 Extradural and subdural abscess, unspecified
0.463 0.537 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.463 0.537 0.000
E03.8 Other specified hypothyroidism
0.001 0.537 0.462
G83.8 Other specified paralytic syndromes
0.461 0.539 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.540 0.460
G06.1 Intraspinal abscess and granuloma
0.460 0.540 0.000
G25 Other extrapyramidal and movement disorders
0.459 0.541 0.000
G24.8 Other dystonia
0.458 0.541 0.000
E88.3 Tumour lysis syndrome
0.000 0.542 0.457
E75.5 Other lipid storage disorders
0.000 0.542 0.457
K90 Intestinal malabsorption
0.000 0.544 0.456
G93.4 Encephalopathy, unspecified
0.452 0.548 0.000
G80.9 Infantile cerebral palsy, unspecified
0.452 0.548 0.000
G00.8 Other bacterial meningitis
0.449 0.551 0.000
G00.3 Staphylococcal meningitis
0.449 0.551 0.000
G00.2 Streptococcal meningitis
0.449 0.551 0.000
G00.0 Haemophilus meningitis
0.449 0.551 0.000
G92 Toxic encephalopathy
0.447 0.553 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.445 0.555 0.000
G24.3 Spasmodic torticollis
0.445 0.555 0.000
E13.3 With ophthalmic complications
0.000 0.555 0.444
E88.8 Other specified metabolic disorders
0.000 0.557 0.443
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.557 0.443
E21.4 Other specified disorders of parathyroid gland
0.000 0.557 0.443
G93.8 Other specified disorders of brain
0.438 0.562 0.000
G30.1 Alzheimer's disease with late onset
0.437 0.562 0.000
G91.8 Other hydrocephalus
0.433 0.567 0.000
L40-L45 Papulosquamous disorders
0.000 0.568 0.432
G11.9 Hereditary ataxia, unspecified
0.431 0.569 0.000
G24.4 Idiopathic orofacial dystonia
0.430 0.570 0.000
G24.2 Idiopathic nonfamilial dystonia
0.430 0.570 0.000
G24.1 Idiopathic familial dystonia
0.430 0.570 0.000
G24.0 Drug-induced dystonia
0.430 0.570 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.430 0.570 0.000
G71 Primary disorders of muscles
0.429 0.571 0.000
G12 Spinal muscular atrophy and related syndromes
0.429 0.571 0.000
G06.0 Intracranial abscess and granuloma
0.427 0.572 0.000
E31 Polyglandular dysfunction
0.000 0.574 0.426
K50.8 Other Crohn's disease
0.423 0.577 0.000
E23.6 Other disorders of pituitary gland
0.000 0.577 0.423
I25.4 Coronary artery aneurysm
0.000 0.579 0.420
G80.4 Ataxic cerebral palsy
0.420 0.579 0.000
G80.3 Dyskinetic cerebral palsy
0.420 0.579 0.000
G80.1 Spastic diplegia
0.420 0.579 0.000
G80.0 Spastic cerebral palsy
0.420 0.579 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.581 0.419
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.581 0.419
G11.8 Other hereditary ataxias
0.418 0.582 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.418 0.582 0.000
G11.2 Late-onset cerebellar ataxia
0.418 0.582 0.000
G11.1 Early-onset cerebellar ataxia
0.418 0.582 0.000
G11.0 Congenital nonprogressive ataxia
0.418 0.582 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.417 0.582 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.584 0.416
E45 Retarded development following protein-energy malnutrition
0.000 0.584 0.416
E43 Unspecified severe protein-energy malnutrition
0.000 0.584 0.416
E42 Marasmic kwashiorkor
0.000 0.584 0.416
E41 Nutritional marasmus
0.000 0.584 0.416
E40 Kwashiorkor
0.000 0.584 0.416
E20 Hypoparathyroidism
0.000 0.586 0.414
E34 Other endocrine disorders
0.000 0.587 0.413
E06.9 Thyroiditis, unspecified
0.000 0.587 0.413
G72 Other myopathies
0.413 0.587 0.000
G80.2 Infantile hemiplegia
0.413 0.587 0.000
E06.5 Other chronic thyroiditis
0.000 0.589 0.411
E06.4 Drug-induced thyroiditis
0.000 0.589 0.411
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.589 0.411
E06.1 Subacute thyroiditis
0.000 0.589 0.411
E06.0 Acute thyroiditis
0.000 0.589 0.411
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.408 0.591 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.408 0.591 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.593 0.407
G90 Disorders of autonomic nervous system
0.399 0.601 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.603 0.397
G70 Myasthenia gravis and other myoneural disorders
0.396 0.604 0.000
G83.2 Monoplegia of upper limb
0.393 0.606 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.393 0.607 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.607 0.393
E23.2 Diabetes insipidus
0.000 0.608 0.392
E23.7 Disorder of pituitary gland, unspecified
0.000 0.609 0.391
E22.0 Acromegaly and pituitary gigantism
0.000 0.612 0.388
G82.5 Tetraplegia, unspecified
0.387 0.613 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.386 0.614 0.000
G02.1 Meningitis in mycoses
0.386 0.614 0.000
G93.5 Compression of brain
0.386 0.614 0.000
E22.1 Hyperprolactinaemia
0.000 0.615 0.385
E29 Testicular dysfunction
0.000 0.617 0.383
G25.3 Myoclonus
0.383 0.617 0.000
G95 Other diseases of spinal cord
0.383 0.617 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.617 0.382
G82.3 Flaccid tetraplegia
0.377 0.623 0.000
G82.0 Flaccid paraplegia
0.377 0.623 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.624 0.376
E22.8 Other hyperfunction of pituitary gland
0.000 0.624 0.376
E65-E68 Obesity and other hyperalimentation
0.000 0.625 0.375
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.625 0.375
E23.1 Drug-induced hypopituitarism
0.000 0.625 0.375
E21.2 Other hyperparathyroidism
0.000 0.625 0.375
G97.1 Other reaction to spinal and lumbar puncture
0.374 0.626 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.629 0.371
G96 Other disorders of central nervous system
0.365 0.635 0.000
E28 Ovarian dysfunction
0.000 0.636 0.364
G71.0 Muscular dystrophy
0.364 0.636 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.179 0.639 0.182
E83.8 Other disorders of mineral metabolism
0.179 0.639 0.182
E83.2 Disorders of zinc metabolism
0.179 0.639 0.182
E83.0 Disorders of copper metabolism
0.179 0.639 0.182
G21.9 Secondary Parkinsonism, unspecified
0.360 0.640 0.000
G21.8 Other secondary Parkinsonism
0.360 0.640 0.000
G21.4 Vascular parkinsonism
0.360 0.640 0.000
G21.3 Postencephalitic Parkinsonism
0.360 0.640 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.360 0.640 0.000
G21.1 Other drug-induced secondary Parkinsonism
0.360 0.640 0.000
G21.0 Malignant neuroleptic syndrome
0.360 0.640 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.360 0.640 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.360 0.640 0.000
G23.3 Multiple system atrophy, cerebellar type
0.360 0.640 0.000
G23.2 Striatonigral degeneration
0.360 0.640 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.360 0.640 0.000
G23.0 Hallervorden-Spatz disease
0.360 0.640 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.640 0.360
G95.0 Syringomyelia and syringobulbia
0.357 0.643 0.000
G93.7 Reye's syndrome
0.356 0.644 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.644 0.356
G02.0 Meningitis in viral diseases classified elsewhere
0.355 0.644 0.000
E26 Hyperaldosteronism
0.000 0.646 0.354
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.352 0.648 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.352 0.648 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.352 0.648 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.352 0.648 0.000
G72.9 Myopathy, unspecified
0.351 0.649 0.000
E24.8 Other Cushing's syndrome
0.000 0.651 0.348
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.651 0.348
E24.3 Ectopic ACTH syndrome
0.000 0.651 0.348
E24.2 Drug-induced Cushing's syndrome
0.000 0.651 0.348
E24.1 Nelson's syndrome
0.000 0.651 0.348
E23.0 Hypopituitarism
0.000 0.652 0.348
G31.8 Other specified degenerative diseases of nervous system
0.347 0.653 0.000
G24.5 Blepharospasm
0.342 0.658 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.342 0.658 0.000
G25.0 Essential tremor
0.341 0.659 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.659 0.340

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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