TreeWAS – Variant ID: rs2075292

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.189	0.811
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.682	0.318
E78.2 Mixed hyperlipidaemia	0.000	0.716	0.284
E78.5 Hyperlipidaemia, unspecified	0.000	0.740	0.260
E78.1 Pure hyperglyceridaemia	0.000	0.771	0.229
E78.3 Hyperchylomicronaemia	0.000	0.782	0.218
E78.6 Lipoprotein deficiency	0.000	0.793	0.207
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.799	0.201
E78.4 Other hyperlipidaemia	0.000	0.820	0.180
E78.8 Other disorders of lipoprotein metabolism	0.000	0.826	0.174
G93.3 Postviral fatigue syndrome	0.000	0.969	0.031
J69.0 Pneumonitis due to food and vomit	0.029	0.971	0.000
M16.9 Coxarthrosis, unspecified	0.026	0.974	0.000
M16.1 Other primary coxarthrosis	0.025	0.975	0.000
M16 Coxarthrosis [arthrosis of hip]	0.025	0.975	0.000
J69 Pneumonitis due to solids and liquids	0.024	0.976	0.000
M16.0 Primary coxarthrosis, bilateral	0.022	0.978	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.021	0.979	0.000
J60-J70 Lung diseases due to external agents	0.021	0.979	0.000
M16.7 Other secondary coxarthrosis	0.021	0.979	0.000
M16.5 Other posttraumatic coxarthrosis	0.019	0.981	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.018	0.982	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.017	0.982	0.000
J69.1 Pneumonitis due to oils and essences	0.017	0.983	0.000
I10 Essential (primary) hypertension	0.000	0.983	0.017
J64 Unspecified pneumoconiosis	0.017	0.983	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.017	0.983	0.000
J60 Coalworker's pneumoconiosis	0.016	0.984	0.000
M16.3 Other dysplastic coxarthrosis	0.016	0.984	0.000
J70 Respiratory conditions due to other external agents	0.016	0.984	0.000
J69.8 Pneumonitis due to other solids and liquids	0.015	0.985	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.015	0.985	0.000
J66 Airway disease due to specific organic dust	0.015	0.985	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.015	0.985	0.000
J65 Pneumoconiosis associated with tuberculosis	0.015	0.985	0.000
J62 Pneumoconiosis due to dust containing silica	0.015	0.985	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.014	0.985	0.000
H26.9 Cataract, unspecified	0.000	0.987	0.013
J70.1 Chronic and other pulmonary manifestations due to radiation	0.012	0.988	0.000
J67.2 Bird fancier's lung	0.011	0.988	0.000
J70.9 Respiratory conditions due to unspecified external agent	0.011	0.989	0.000
J70.8 Respiratory conditions due to other specified external agents	0.011	0.989	0.000
J70.3 Chronic drug-induced interstitial lung disorders	0.011	0.989	0.000
J70.2 Acute drug-induced interstitial lung disorders	0.011	0.989	0.000
J70.0 Acute pulmonary manifestations due to radiation	0.011	0.989	0.000
J70.4 Drug-induced interstitial lung disorder, unspecified	0.011	0.989	0.000
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.011	0.989	0.000
J63.5 Stannosis	0.011	0.989	0.000
J63.4 Siderosis	0.011	0.989	0.000
J63.3 Graphite fibrosis (of lung)	0.011	0.989	0.000
J63.2 Berylliosis	0.011	0.989	0.000
J63.1 Bauxite fibrosis (of lung)	0.011	0.989	0.000
J63.0 Aluminosis (of lung)	0.011	0.989	0.000
J66.8 Airway disease due to other specific organic dusts	0.011	0.989	0.000
J66.2 Cannabinosis	0.011	0.989	0.000
J66.1 Flax-dresser's disease	0.011	0.989	0.000
J66.0 Byssinosis	0.011	0.989	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.011	0.989	0.000
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.011	0.989	0.000
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.011	0.989	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.989	0.011
J62.0 Pneumoconiosis due to talc dust	0.011	0.989	0.000
J67.7 Air-conditioner and humidifier lung	0.010	0.989	0.000
J67.6 Maple-bark-stripper's lung	0.010	0.989	0.000
J67.5 Mushroom-worker's lung	0.010	0.989	0.000
J67.4 Maltworker's lung	0.010	0.989	0.000
J67.3 Suberosis	0.010	0.989	0.000
J67.1 Bagassosis	0.010	0.989	0.000
J67.0 Farmer's lung	0.010	0.989	0.000
J62.8 Pneumoconiosis due to other dust containing silica	0.010	0.990	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.990	0.010
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.010	0.990	0.000
I71 Aortic aneurysm and dissection	0.000	0.990	0.010
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.991	0.009
I71.0 Dissection of aorta [any part]	0.000	0.992	0.008
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.008	0.992	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.992	0.008
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.992	0.008
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.992	0.007
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.992	0.007
S92.00 Fracture of calcaneus (closed)	0.000	0.993	0.007
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.993	0.007
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.993	0.007
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.993	0.007
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.994	0.006
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.994	0.006
G93 Other disorders of brain	0.000	0.994	0.006
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.006	0.994	0.000
I74 Arterial embolism and thrombosis	0.000	0.994	0.006
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.994	0.006
D68.2 Hereditary deficiency of other clotting factors	0.006	0.994	0.000
D05.0 Lobular carcinoma in situ	0.000	0.995	0.005
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.995	0.005
Y45.0 Opioids and related analgesics	0.005	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.995	0.005
D05 Carcinoma in situ of breast	0.000	0.995	0.005
I74.8 Embolism and thrombosis of other arteries	0.000	0.995	0.005
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.995	0.005
R29.6 Tendency to fall, not elsewhere classified	0.005	0.995	0.000
G93.8 Other specified disorders of brain	0.000	0.995	0.005
G93.7 Reye's syndrome	0.000	0.995	0.005
G93.2 Benign intracranial hypertension	0.000	0.995	0.005
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.995	0.005
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.995	0.005
C45.0 Mesothelioma of pleura	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
D05.7 Other carcinoma in situ of breast	0.000	0.995	0.005
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.995	0.005
S92.0 Fracture of calcaneus	0.000	0.995	0.004
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.996	0.004
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.996	0.004
D68.5 Primary Thrombophilia	0.004	0.996	0.000
G93.4 Encephalopathy, unspecified	0.000	0.996	0.004
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.996	0.004
C45 Mesothelioma	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
G93.5 Compression of brain	0.000	0.996	0.004
T42.4 Benzodiazepines	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.996	0.000
I70 Atherosclerosis	0.000	0.996	0.004
D03.5 Melanoma in situ of trunk	0.000	0.996	0.004
D03 Melanoma in situ	0.000	0.996	0.004
H26 Other cataract	0.000	0.996	0.004
Y45.5 4-Aminophenol derivatives	0.004	0.996	0.000
C45.7 Mesothelioma of other sites	0.004	0.996	0.000
I72 Other aneurysm	0.000	0.996	0.004
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.996	0.004
D03.4 Melanoma in situ of scalp and neck	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.996	0.004
I78 Diseases of capillaries	0.000	0.996	0.004
G93.6 Cerebral oedema	0.000	0.996	0.003
S92.01 Fracture of calcaneus (open)	0.000	0.996	0.003
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.996	0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.996	0.004
S30.0 Contusion of lower back and pelvis	0.000	0.996	0.004
G93.9 Disorder of brain, unspecified	0.000	0.996	0.003
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.996	0.004
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.996	0.003
Y45.8 Other analgesics and antipyretics	0.003	0.996	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.996	0.004
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
D03.0 Melanoma in situ of lip	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.997	0.003
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.003	0.997	0.000
H26.0 Infantile, juvenile and presenile cataract	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.003	0.997	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.003
H26.3 Drug-induced cataract	0.000	0.997	0.003
I72.4 Aneurysm of artery of lower extremity	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
I72.0 Aneurysm of carotid artery	0.000	0.997	0.003
I70.0 Atherosclerosis of aorta	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
D03.8 Melanoma in situ of other sites	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.003	0.997	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.997	0.000
I84.9 Unspecified haemorrhoids without complication	0.000	0.997	0.003
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.997	0.003
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
G93.0 Cerebral cysts	0.000	0.997	0.003
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.997	0.003
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I78.8 Other diseases of capillaries	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.003	0.997	0.000
S30.2 Contusion of external genital organs	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
H26.1 Traumatic cataract	0.000	0.997	0.003
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.997	0.003
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
R29.1 Meningismus	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
S30.1 Contusion of abdominal wall	0.000	0.997	0.003
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.997	0.003
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
H26.8 Other specified cataract	0.000	0.997	0.003
R29.0 Tetany	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
I72.9 Aneurysm of unspecified site	0.000	0.997	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.000	0.997	0.002
R29.4 Clicking hip	0.003	0.997	0.000
R29.3 Abnormal posture	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.997	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.997	0.000
T44.0 Anticholinesterase agents	0.002	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
H26.2 Complicated cataract	0.000	0.997	0.002
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.997	0.002
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.997	0.000
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
D69.0 Allergic purpura	0.002	0.997	0.000
T42.1 Iminostilbenes	0.002	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.997	0.002
D68.8 Other specified coagulation defects	0.002	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.997	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.997	0.002
D69.2 Other nonthrombocytopenic purpura	0.002	0.997	0.000
I72.3 Aneurysm of iliac artery	0.000	0.997	0.002
Y40.0 Penicillins	0.002	0.997	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.997	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.002	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
H26.4 After-cataract	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
R29.2 Abnormal reflex	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
I79.1 Aortitis in diseases classified elsewhere	0.000	0.998	0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
D00-D09 In situ neoplasms	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.002	0.998	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
T46.7 Peripheral vasodilators	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
T48.4 Expectorants	0.002	0.998	0.000
T48.3 Antitussives	0.002	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
T48.0 Oxytocic drugs	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.002	0.998	0.000
S32.5 Fracture of pubis	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
E75.5 Other lipid storage disorders	0.000	0.998	0.002
T36.3 Macrolides	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.998	0.002
T36.4 Tetracyclines	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
T37.5 Antiviral drugs	0.002	0.998	0.000
T37.4 Anthelminthics	0.002	0.998	0.000
T37.3 Other antiprotozoal drugs	0.002	0.998	0.000
T37.1 Antimycobacterial drugs	0.002	0.998	0.000
T37.0 Sulphonamides	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.000	0.998	0.002
C48.1 Specified parts of peritoneum	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
C46 Kaposi's sarcoma	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
N48 Other disorders of penis	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.998	0.001
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y57.6 Other diagnostic agents	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
Q24.0 Dextrocardia	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
E75.2 Other sphingolipidosis	0.000	0.998	0.002
N48.3 Priapism	0.000	0.998	0.002
T36.0 Penicillins	0.002	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.002
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.002	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Q25 Congenital malformations of great arteries	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.000	0.998	0.002
T40.1 Heroin	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
D04 Carcinoma in situ of skin	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
S92.1 Fracture of talus	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.002	0.998	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.000	0.998	0.002
D04.9 Skin, unspecified	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
E84 Cystic fibrosis	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.000	0.998	0.002
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.998	0.002
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations