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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2075423
log Bayes Factor = 4.61144
Chromosome 1   position 214,154,719  (GRCh37) Explore rs2075423 on Ensembl!
Variant rs2075423 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.009 0.991
E10-E14 Diabetes mellitus
0.000 0.062 0.938
E10 Insulin-dependent diabetes mellitus
0.000 0.076 0.924
E11.6 With other specified complications
0.000 0.096 0.904
E11.2 With renal complications
0.000 0.104 0.896
E10.3 With ophthalmic complications
0.000 0.118 0.882
E11.5 With peripheral circulatory complications
0.000 0.126 0.874
E11.3 With ophthalmic complications
0.000 0.160 0.840
E10.6 With other specified complications
0.000 0.164 0.835
E10.4 With neurological complications
0.000 0.179 0.821
E10.8 With unspecified complications
0.000 0.217 0.783
E10.1 With ketoacidosis
0.000 0.242 0.758
E14 Unspecified diabetes mellitus
0.000 0.254 0.746
E11.7 With multiple complications
0.000 0.290 0.710
E14.3 With ophthalmic complications
0.000 0.327 0.673
E12 Malnutrition-related diabetes mellitus
0.000 0.328 0.672
E13 Other specified diabetes mellitus
0.000 0.343 0.657
E10.2 With renal complications
0.000 0.361 0.639
E14.6 With other specified complications
0.000 0.387 0.613
E11.4 With neurological complications
0.000 0.388 0.612
E11.8 With unspecified complications
0.000 0.393 0.607
E10.7 With multiple complications
0.000 0.424 0.576
E11.0 With coma
0.000 0.436 0.564
E10.0 With coma
0.000 0.438 0.561
O03 Spontaneous abortion
0.554 0.446 0.000
O03.4 Incomplete, without complication
0.552 0.448 0.000
O03.9 Complete or unspecified, without complication
0.540 0.460 0.000
E14.2 Withrenal complications
0.000 0.462 0.538
E14.7 With multiple complications
0.000 0.465 0.535
E14.0 With coma
0.000 0.465 0.535
E10.9 Without complications
0.000 0.480 0.520
E14.1 With ketoacidosis
0.000 0.480 0.520
E14.9 Without complications
0.000 0.481 0.519
O00-O08 Pregnancy with abortive outcome
0.498 0.502 0.000
O04 Medical abortion
0.491 0.509 0.000
E14.8 With unspecified complications
0.000 0.511 0.489
O04.9 Complete or unspecified, without complication
0.484 0.516 0.000
E12.9 Without complications
0.000 0.518 0.482
E12.8 With unspecified complications
0.000 0.518 0.482
E12.7 With multiple complications
0.000 0.518 0.482
E12.6 With other specified complications
0.000 0.518 0.482
E12.5 With peripheral circulatory complications
0.000 0.518 0.482
E12.4 With neurological complications
0.000 0.518 0.482
E12.3 With ophthalmic complications
0.000 0.518 0.482
E12.2 With renal complications
0.000 0.518 0.482
E12.1 With ketoacidosis
0.000 0.518 0.482
E12.0 With coma
0.000 0.518 0.482
O03.8 Complete or unspecified, with other and unspecified complications
0.481 0.519 0.000
E13.8 With unspecified complications
0.000 0.529 0.471
E13.7 With multiple complications
0.000 0.529 0.471
E13.6 With other specified complications
0.000 0.529 0.471
E13.5 With peripheral circulatory complications
0.000 0.529 0.471
E13.4 With neurological complications
0.000 0.529 0.471
E13.3 With ophthalmic complications
0.000 0.529 0.471
E13.2 With renal complications
0.000 0.529 0.471
E13.1 With ketoacidosis
0.000 0.529 0.471
E13.0 With coma
0.000 0.529 0.471
E10.5 With peripheral circulatory complications
0.000 0.538 0.462
E13.9 Without complications
0.000 0.544 0.456
E14.5 With peripheral circulatory complications
0.000 0.546 0.454
E11.1 With ketoacidosis
0.000 0.548 0.451
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.432 0.568 0.000
O02 Other abnormal products of conception
0.424 0.576 0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.423 0.577 0.000
E14.4 With neurological complications
0.000 0.590 0.410
O03.7 Complete or unspecified, complicated by embolism
0.397 0.603 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.397 0.603 0.000
O03.2 Incomplete, complicated by embolism
0.397 0.603 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.397 0.603 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.397 0.603 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.394 0.606 0.000
O03.3 Incomplete, with other and unspecified complications
0.388 0.612 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.369 0.630 0.000
O07 Failed attempted abortion
0.357 0.643 0.000
O05 Other abortion
0.357 0.643 0.000
O01 Hydatidiform mole
0.357 0.643 0.000
O04.7 Complete or unspecified, complicated by embolism
0.352 0.648 0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.352 0.648 0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.352 0.648 0.000
O04.3 Incomplete, with other and unspecified complications
0.352 0.648 0.000
O04.2 Incomplete, complicated by embolism
0.352 0.648 0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.352 0.648 0.000
O06 Unspecified abortion
0.347 0.653 0.000
O02.9 Abnormal product of conception, unspecified
0.328 0.672 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.321 0.679 0.000
O02.8 Other specified abnormal products of conception
0.304 0.696 0.000
O04.4 Incomplete, without complication
0.264 0.736 0.000
O01.9 Hydatidiform mole, unspecified
0.256 0.744 0.000
O01.1 Incomplete and partial hydatidiform mole
0.256 0.744 0.000
O01.0 Classical hydatidiform mole
0.256 0.744 0.000
O05.9 Complete or unspecified, without complication
0.256 0.744 0.000
O05.8 Complete or unspecified, with other and unspecified complications
0.256 0.744 0.000
O05.7 Complete or unspecified, complicated by embolism
0.256 0.744 0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.256 0.744 0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.256 0.744 0.000
O05.4 Incomplete, without complication
0.256 0.744 0.000
O05.3 Incomplete, with other and unspecified complications
0.256 0.744 0.000
O05.2 Incomplete, complicated by embolism
0.256 0.744 0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage
0.256 0.744 0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection
0.256 0.744 0.000
O07.9 Other and unspecified failed attempted abortion, without complication
0.256 0.744 0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications
0.256 0.744 0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism
0.256 0.744 0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
0.256 0.744 0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection
0.256 0.744 0.000
O07.4 Failed medical abortion, without complication
0.256 0.744 0.000
O07.3 Failed medical abortion, with other and unspecified complications
0.256 0.744 0.000
O07.2 Failed medical abortion, complicated by embolism
0.256 0.744 0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage
0.256 0.744 0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection
0.256 0.744 0.000
O06.8 Complete or unspecified, with other and unspecified complications
0.249 0.751 0.000
O06.7 Complete or unspecified, complicated by embolism
0.249 0.751 0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.249 0.751 0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.249 0.751 0.000
O06.4 Incomplete, without complication
0.249 0.751 0.000
O06.3 Incomplete, with other and unspecified complications
0.249 0.751 0.000
O06.2 Incomplete, complicated by embolism
0.249 0.751 0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage
0.249 0.751 0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection
0.249 0.751 0.000
O00 Ectopic pregnancy
0.242 0.758 0.000
O06.9 Complete or unspecified, without complication
0.238 0.762 0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified
0.230 0.770 0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.3 Shock following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy
0.230 0.770 0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy
0.193 0.807 0.000
O00.8 Other ectopic pregnancy
0.173 0.826 0.000
O00.2 Ovarian pregnancy
0.173 0.826 0.000
O00.0 Abdominal pregnancy
0.173 0.826 0.000
O02.1 Missed abortion
0.161 0.839 0.000
O00.1 Tubal pregnancy
0.152 0.847 0.000
O00.9 Ectopic pregnancy, unspecified
0.101 0.899 0.001
K56.5 Intestinal adhesions [bands] with obstruction
0.040 0.960 0.000
F20.0 Paranoid schizophrenia
0.039 0.961 0.000
F20 Schizophrenia
0.038 0.962 0.000
F20.9 Schizophrenia, unspecified
0.036 0.964 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.034 0.966 0.000
F25 Schizoaffective disorders
0.031 0.969 0.000
F29 Unspecified nonorganic psychosis
0.030 0.970 0.000
F20.8 Other schizophrenia
0.027 0.973 0.000
F20.6 Simple schizophrenia
0.027 0.973 0.000
F20.4 Postschizophrenic depression
0.027 0.973 0.000
F20.3 Undifferentiated schizophrenia
0.027 0.973 0.000
F20.2 Catatonic schizophrenia
0.027 0.973 0.000
F20.1 Hebephrenic schizophrenia
0.027 0.973 0.000
F25.2 Schizoaffective disorder, mixed type
0.027 0.973 0.000
F22 Persistent delusional disorders
0.026 0.974 0.000
F25.9 Schizoaffective disorder, unspecified
0.026 0.974 0.000
F25.1 Schizoaffective disorder, depressive type
0.026 0.974 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.975 0.025
F20.5 Residual schizophrenia
0.024 0.975 0.000
F28 Other nonorganic psychotic disorders
0.024 0.976 0.000
F24 Induced delusional disorder
0.024 0.976 0.000
F21 Schizotypal disorder
0.024 0.976 0.000
F23 Acute and transient psychotic disorders
0.023 0.977 0.000
F25.8 Other schizoaffective disorders
0.023 0.977 0.000
F22.0 Delusional disorder
0.021 0.979 0.000
E83.1 Disorders of iron metabolism
0.000 0.979 0.021
F25.0 Schizoaffective disorder, manic type
0.020 0.979 0.000
F22.9 Persistent delusional disorder, unspecified
0.019 0.981 0.000
F22.8 Other persistent delusional disorders
0.019 0.981 0.000
E83 Disorders of mineral metabolism
0.000 0.981 0.019
E83.3 Disorders of phosphorus metabolism
0.000 0.982 0.018
E50-E64 Other nutritional deficiencies
0.000 0.983 0.017
F23.8 Other acute and transient psychotic disorders
0.016 0.983 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.016 0.983 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.016 0.983 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.016 0.983 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.984 0.016
E65-E68 Obesity and other hyperalimentation
0.000 0.984 0.016
F23.9 Acute and transient psychotic disorder, unspecified
0.016 0.984 0.000
E83.5 Disorders of calcium metabolism
0.000 0.984 0.016
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.015 0.984 0.000
E70-E90 Metabolic disorders
0.000 0.984 0.016
E40-E46 Malnutrition
0.000 0.985 0.015
E55 Vitamin D deficiency
0.000 0.985 0.015
E65 Localised adiposity
0.000 0.985 0.015
E73 Lactose intolerance
0.000 0.985 0.014
H36.0 Diabetic retinopathy
0.000 0.986 0.014
E73.9 Lactose intolerance, unspecified
0.000 0.986 0.014
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.986 0.014
E83.8 Other disorders of mineral metabolism
0.000 0.986 0.014
E83.2 Disorders of zinc metabolism
0.000 0.986 0.014
E83.0 Disorders of copper metabolism
0.000 0.986 0.014
E55.9 Vitamin D deficiency, unspecified
0.000 0.986 0.014
E74 Other disorders of carbohydrate metabolism
0.000 0.987 0.013
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.987 0.013
E51 Thiamine deficiency
0.000 0.987 0.013
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.987 0.012
E63 Other nutritional deficiencies
0.000 0.987 0.012
E50 Vitamin A deficiency
0.000 0.987 0.012
E60 Dietary zinc deficiency
0.000 0.987 0.012
E59 Dietary selenium deficiency
0.000 0.987 0.012
E52 Niacin deficiency [pellagra]
0.000 0.987 0.012
E56 Other vitamin deficiencies
0.000 0.988 0.012
E53 Deficiency of other B group vitamins
0.000 0.988 0.012
E15 Nondiabetic hypoglycaemic coma
0.000 0.988 0.012
E67 Other hyperalimentation
0.000 0.988 0.012
E68 Sequelae of hyperalimentation
0.000 0.988 0.012
E58 Dietary calcium deficiency
0.000 0.988 0.012
D86.9 Sarcoidosis, unspecified
0.012 0.988 0.000
E77 Disorders of glycoprotein metabolism
0.000 0.988 0.011
E76 Disorders of glycosaminoglycan metabolism
0.000 0.988 0.011
E72 Other disorders of amino-acid metabolism
0.000 0.988 0.011
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.988 0.011
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.988 0.011
E79 Disorders of purine and pyrimidine metabolism
0.000 0.989 0.011
E54 Ascorbic acid deficiency
0.000 0.989 0.011
E70 Disorders of aromatic amino-acid metabolism
0.000 0.989 0.011
D86 Sarcoidosis
0.011 0.989 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.989 0.011
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.989 0.011
E45 Retarded development following protein-energy malnutrition
0.000 0.989 0.011
E43 Unspecified severe protein-energy malnutrition
0.000 0.989 0.011
E42 Marasmic kwashiorkor
0.000 0.989 0.011
E41 Nutritional marasmus
0.000 0.989 0.011
E40 Kwashiorkor
0.000 0.989 0.011
E55.0 Rickets, active
0.000 0.989 0.011
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.989 0.011
D86.0 Sarcoidosis of lung
0.011 0.989 0.000
E73.8 Other lactose intolerance
0.000 0.989 0.010
E73.1 Secondary lactase deficiency
0.000 0.989 0.010
E73.0 Congenital lactase deficiency
0.000 0.989 0.010
E84 Cystic fibrosis
0.000 0.989 0.010
E61 Deficiency of other nutrient elements
0.000 0.989 0.010
E80.2 Other porphyria
0.000 0.989 0.010
D80 Immunodeficiency with predominantly antibody defects
0.010 0.990 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.990 0.010
E88 Other metabolic disorders
0.000 0.990 0.010
D86.8 Sarcoidosis of other and combined sites
0.010 0.990 0.000
D80-D89 Certain disorders involving the immune mechanism
0.010 0.990 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.990 0.009
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.990 0.009
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.990 0.009
E74.2 Disorders of galactose metabolism
0.000 0.990 0.009
E74.1 Disorders of fructose metabolism
0.000 0.990 0.009
E74.0 Glycogen storage disease
0.000 0.990 0.009
E80.1 Porphyria cutanea tarda
0.000 0.990 0.010
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.010 0.990 0.000
E80.4 Gilbert's syndrome
0.000 0.990 0.009
D84 Other immunodeficiencies
0.009 0.991 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.991 0.009
E80.5 Crigler-Najjar syndrome
0.000 0.991 0.009
E80.3 Defects of catalase and peroxydase
0.000 0.991 0.009
E80.0 Hereditary erythropoietic porphyria
0.000 0.991 0.009
E51.2 Wernicke's encephalopathy
0.000 0.991 0.009
E51.9 Thiamine deficiency, unspecified
0.000 0.991 0.009
E51.8 Other manifestations of thiamine deficiency
0.000 0.991 0.009
E51.1 Beriberi
0.000 0.991 0.009
E50.9 Vitamin A deficiency, unspecified
0.000 0.991 0.009
E50.8 Other manifestations of vitamin A deficiency
0.000 0.991 0.009
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.991 0.009
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.991 0.009
E50.5 Vitamin A deficiency with night blindness
0.000 0.991 0.009
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.991 0.009
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.991 0.009
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.991 0.009
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.991 0.009
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.991 0.009
E63.9 Nutritional deficiency, unspecified
0.000 0.991 0.009
E63.8 Other specified nutritional deficiencies
0.000 0.991 0.009
E63.1 Imbalance of constituents of food intake
0.000 0.991 0.009
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.991 0.009
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.991 0.009
E64.8 Sequelae of other nutritional deficiencies
0.000 0.991 0.009
E64.3 Sequelae of rickets
0.000 0.991 0.009
E64.2 Sequelae of vitamin C deficiency
0.000 0.991 0.009
E64.1 Sequelae of vitamin A deficiency
0.000 0.991 0.009
E64.0 Sequelae of protein-energy malnutrition
0.000 0.991 0.009
E53.9 Vitamin B deficiency, unspecified
0.000 0.991 0.009
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.009 0.991 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.991 0.009
E56.8 Deficiency of other vitamins
0.000 0.991 0.009
E56.0 Deficiency of vitamin E
0.000 0.991 0.009
E53.1 Pyridoxine deficiency
0.000 0.991 0.009
E53.0 Riboflavin deficiency
0.000 0.991 0.009
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.991 0.009
E80.6 Other disorders of bilirubin metabolism
0.000 0.991 0.009
D84.9 Immunodeficiency, unspecified
0.009 0.991 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.009 0.991 0.000
D86.1 Sarcoidosis of lymph nodes
0.009 0.991 0.000
E67.8 Other specified hyperalimentation
0.000 0.991 0.009
E67.3 Hypervitaminosis D
0.000 0.991 0.009
E67.2 Megavitamin-B6 syndrome
0.000 0.991 0.009
E67.1 Hypercarotenaemia
0.000 0.991 0.009
E67.0 Hypervitaminosis A
0.000 0.991 0.009
E56.1 Deficiency of vitamin K
0.000 0.991 0.009
E46 Unspecified protein-energy malnutrition
0.000 0.991 0.008
E71.3 Disorders of fatty-acid metabolism
0.000 0.991 0.008
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.991 0.008
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.991 0.008
E71.0 Maple-syrup-urine disease
0.000 0.991 0.008
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.991 0.008
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.991 0.008
E72.5 Disorders of glycine metabolism
0.000 0.991 0.008
E72.4 Disorders of ornithine metabolism
0.000 0.991 0.008
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.991 0.008
E72.2 Disorders of urea cycle metabolism
0.000 0.991 0.008
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.991 0.008
E72.0 Disorders of amino-acid transport
0.000 0.991 0.008
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.991 0.008
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.991 0.008
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.991 0.008
E76.2 Other mucopolysaccharidoses
0.000 0.991 0.008
E76.1 Mucopolysaccharidosis, type II
0.000 0.991 0.008
E76.0 Mucopolysaccharidosis, type I
0.000 0.991 0.008
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.991 0.008
E77.8 Other disorders of glycoprotein metabolism
0.000 0.991 0.008
E77.1 Defects in glycoprotein degradation
0.000 0.991 0.008
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.991 0.008
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.991 0.008
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.991 0.008
E79.1 Lesch-Nyhan syndrome
0.000 0.991 0.008
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.992 0.008
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.992 0.008
E70.2 Disorders of tyrosine metabolism
0.000 0.992 0.008
E70.1 Other hyperphenylalaninaemias
0.000 0.992 0.008
E70.0 Classical phenylketonuria
0.000 0.992 0.008
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.992 0.008
E70.3 Albinism
0.000 0.992 0.008
E85 Amyloidosis
0.000 0.992 0.008
E44.1 Mild protein-energy malnutrition
0.000 0.992 0.008
E44.0 Moderate protein-energy malnutrition
0.000 0.992 0.008
E53.8 Deficiency of other specified B group vitamins
0.000 0.992 0.008
E61.2 Magnesium deficiency
0.000 0.992 0.008
E75.6 Lipid storage disorder, unspecified
0.000 0.992 0.008
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.992 0.008
E75.3 Sphingolipidosis, unspecified
0.000 0.992 0.008
E75.2 Other sphingolipidosis
0.000 0.992 0.008
E75.1 Other gangliosidosis
0.000 0.992 0.008
E75.0 GM2 gangliosidosis
0.000 0.992 0.008
E88.3 Tumour lysis syndrome
0.000 0.992 0.008
E88.8 Other specified metabolic disorders
0.000 0.992 0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.008 0.992 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.992 0.008
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.992 0.008
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.992 0.008
E88.2 Lipomatosis, not elsewhere classified
0.000 0.992 0.008
E61.9 Deficiency of nutrient element, unspecified
0.000 0.992 0.008
E61.8 Deficiency of other specified nutrient elements
0.000 0.992 0.008
E61.7 Deficiency of multiple nutrient elements
0.000 0.992 0.008
E61.6 Vanadium deficiency
0.000 0.992 0.008
E61.5 Molybdenum deficiency
0.000 0.992 0.008
E61.4 Chromium deficiency
0.000 0.992 0.008
E61.3 Manganese deficiency
0.000 0.992 0.008
E61.0 Copper deficiency
0.000 0.992 0.008
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.008 0.992 0.000
E06.3 Autoimmune thyroiditis
0.000 0.992 0.008
D80.8 Other immunodeficiencies with predominantly antibody defects
0.008 0.992 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.008 0.992 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.008 0.992 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.008 0.992 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.008 0.992 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.008 0.992 0.000
E75.5 Other lipid storage disorders
0.000 0.992 0.007
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.992 0.007
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.992 0.007
E16.4 Abnormal secretion of gastrin
0.000 0.992 0.007
E16.3 Increased secretion of glucagon
0.000 0.992 0.007
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.992 0.007
S01.2 Open wound of nose
0.000 0.992 0.008
E88.9 Metabolic disorder, unspecified
0.000 0.993 0.007
D83 Common variable immunodeficiency
0.007 0.993 0.000
D84.8 Other specified immunodeficiencies
0.007 0.993 0.000
D81 Combined immunodeficiencies
0.007 0.993 0.000
D84.1 Defects in the complement system
0.007 0.993 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.007 0.993 0.000
E00-E07 Disorders of thyroid gland
0.000 0.993 0.007
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.993 0.007
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.007 0.993 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.993 0.007
E06 Thyroiditis
0.000 0.993 0.006
D82 Immunodeficiency associated with other major defects
0.007 0.993 0.000
E85.9 Amyloidosis, unspecified
0.000 0.994 0.006
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.994 0.006
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.994 0.006
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.994 0.006
E16.1 Other hypoglycaemia
0.000 0.994 0.006
H36 Retinal disorders in diseases classified elsewhere
0.000 0.994 0.006
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.994 0.006
E85.4 Organ-limited amyloidosis
0.000 0.994 0.006
E83.4 Disorders of magnesium metabolism
0.000 0.994 0.006
D83.9 Common variable immunodeficiency, unspecified
0.006 0.994 0.000
F31 Bipolar affective disorder
0.006 0.994 0.000
E85.8 Other amyloidosis
0.000 0.994 0.005
D83.8 Other common variable immunodeficiencies
0.005 0.994 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.005 0.994 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.005 0.994 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.005 0.994 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.006 0.994 0.000
D86.3 Sarcoidosis of skin
0.005 0.994 0.000
E89.4 Postprocedural ovarian failure
0.000 0.994 0.005
D81.9 Combined immunodeficiency, unspecified
0.005 0.994 0.000
D81.8 Other combined immunodeficiencies
0.005 0.994 0.000
D81.7 Major histocompatibility complex class II deficiency
0.005 0.994 0.000
D81.6 Major histocompatibility complex class I deficiency
0.005 0.994 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.005 0.994 0.000
D81.4 Nezelof's syndrome
0.005 0.994 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.005 0.994 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.005 0.994 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.005 0.994 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.005 0.994 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.005 0.995 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.995 0.005
E00 Congenital iodine-deficiency syndrome
0.000 0.995 0.005
F52.2 Failure of genital response
0.005 0.995 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.995 0.005
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.995 0.005
E89.5 Postprocedural testicular hypofunction
0.000 0.995 0.005
E89.1 Postprocedural hypoinsulinaemia
0.000 0.995 0.005
K14.9 Disease of tongue, unspecified
0.000 0.995 0.005
E06.4 Drug-induced thyroiditis
0.000 0.995 0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.995 0.005
E06.1 Subacute thyroiditis
0.000 0.995 0.005
E06.0 Acute thyroiditis
0.000 0.995 0.005
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.005 0.995 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.005 0.995 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.005 0.995 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.005 0.995 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.005 0.995 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.005 0.995 0.000
D82.2 Immunodeficiency with short-limbed stature
0.005 0.995 0.000
D82.0 Wiskott-Aldrich syndrome
0.005 0.995 0.000
F31.9 Bipolar affective disorder, unspecified
0.005 0.995 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.005 0.995 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.995 0.005
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.995 0.005
E06.5 Other chronic thyroiditis
0.000 0.995 0.004
E61.1 Iron deficiency
0.000 0.995 0.005
E89.2 Postprocedural hypoparathyroidism
0.000 0.995 0.005
E85.3 Secondary systemic amyloidosis
0.000 0.995 0.004
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.005 0.995 0.000
S06.5 Traumatic subdural haemorrhage
0.005 0.995 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.995 0.005
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.005 0.995 0.000
H60.9 Otitis externa, unspecified
0.005 0.995 0.000
Chapter V Mental and behavioural disorders
0.005 0.995 0.000
F31.8 Other bipolar affective disorders
0.005 0.995 0.000
D82.1 Di George's syndrome
0.004 0.995 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.995 0.005
E16.2 Hypoglycaemia, unspecified
0.000 0.995 0.005
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.004 0.995 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.005 0.995 0.000
F50 Eating disorders
0.004 0.996 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.004 0.996 0.000
F55 Abuse of non-dependence-producing substances
0.004 0.996 0.000
E07 Other disorders of thyroid
0.000 0.996 0.004
F31.6 Bipolar affective disorder, current episode mixed
0.004 0.996 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.996 0.004
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.996 0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.996 0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.996 0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.996 0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.996 0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.996 0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.996 0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.996 0.004
F50.0 Anorexia nervosa
0.004 0.996 0.000
D89.3 Immune reconstitution syndrome
0.004 0.996 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.004 0.996 0.000
F30-F39 Mood [affective] disorders
0.004 0.996 0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease
0.004 0.996 0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease
0.004 0.996 0.000
F52.7 Excessive sexual drive
0.004 0.996 0.000
F52.6 Nonorganic dyspareunia
0.004 0.996 0.000
F52.5 Nonorganic vaginismus
0.004 0.996 0.000
F52.4 Premature ejaculation
0.004 0.996 0.000
F52.3 Orgasmic dysfunction
0.004 0.996 0.000
F52.1 Sexual aversion and lack of sexual enjoyment
0.004 0.996 0.000
F52.0 Lack or loss of sexual desire
0.004 0.996 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.004 0.996 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.004 0.996 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.004 0.996 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.004 0.996 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.996 0.004
F51 Nonorganic sleep disorders
0.004 0.996 0.000
S80.9 Superficial injury of lower leg, unspecified
0.004 0.996 0.000
F80-F89 Disorders of psychological development
0.004 0.996 0.000
F31.7 Bipolar affective disorder, currently in remission
0.004 0.996 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.004 0.996 0.000
D89.1 Cryoglobulinaemia
0.004 0.996 0.000
F50.9 Eating disorder, unspecified
0.004 0.996 0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.004 0.996 0.000
E78.4 Other hyperlipidaemia
0.000 0.996 0.004
F39 Unspecified mood [affective] disorder
0.004 0.996 0.000
F60-F69 Disorders of adult personality and behaviour
0.004 0.996 0.000
E07.8 Other specified disorders of thyroid
0.000 0.996 0.004
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.003 0.996 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.996 0.003
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.004 0.996 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.003 0.996 0.000
E05.5 Thyroid crisis or storm
0.000 0.996 0.003
E05.4 Thyrotoxicosis factitia
0.000 0.996 0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.996 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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