TreeWAS – Variant ID: rs2084385

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.985	0.015
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.985	0.015
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.985	0.015
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.986	0.014
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.988	0.012
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.988	0.012
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.988	0.012
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.989	0.011
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.989	0.011
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.989	0.011
Z85.5 Personal history of malignant neoplasm of urinary tract	0.010	0.990	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.990	0.010
Z80 Family history of malignant neoplasm	0.000	0.991	0.009
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.991	0.009
I08.0 Disorders of both mitral and aortic valves	0.000	0.991	0.009
K85.9 Acute pancreatitis, unspecified	0.009	0.991	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.991	0.009
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.992	0.008
C44.5 Skin of trunk	0.000	0.992	0.008
Z80.6 Family history of leukaemia	0.000	0.992	0.008
I08 Multiple valve diseases	0.000	0.992	0.008
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.992	0.008
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.993	0.007
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.993	0.007
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.993	0.007
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.993	0.006
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.994	0.006
I08.9 Multiple valve disease, unspecified	0.000	0.994	0.006
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.994	0.006
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.994	0.006
S62.50 Fracture of thumb (closed)	0.006	0.994	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.995	0.005
K85 Acute pancreatitis	0.005	0.995	0.000
Z63.4 Disappearance and death of family member	0.005	0.995	0.000
T86 Failure and rejection of transplanted organs and tissues	0.000	0.995	0.005
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.995	0.005
G95.9 Disease of spinal cord, unspecified	0.005	0.995	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.995	0.005
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.000	0.995	0.005
K85.2 Alcohol-induced acute pancreatitis	0.005	0.995	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.995	0.005
S62.51 Fracture of thumb (open)	0.005	0.995	0.000
S62.5 Fracture of thumb	0.005	0.995	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.004	0.996	0.000
T86.4 Liver transplant failure and rejection	0.000	0.996	0.004
T86.1 Kidney transplant failure and rejection	0.000	0.996	0.004
K85.8 Other acute pancreatitis	0.004	0.996	0.000
K85.0 Idiopathic acute pancreatitis	0.004	0.996	0.000
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
K85.3 Drug-induced acute pancreatitis	0.004	0.996	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.996	0.004
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.996	0.004
T86.3 Heart-lung transplant failure and rejection	0.000	0.996	0.004
T86.2 Heart transplant failure and rejection	0.000	0.996	0.004
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.000	0.996	0.004
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.996	0.004
K85.1 Biliary acute pancreatitis	0.004	0.996	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.996	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.996	0.004
H53.0 Amblyopia ex anopsia	0.000	0.996	0.004
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.996	0.004
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.996	0.004
I08.8 Other multiple valve diseases	0.001	0.996	0.003
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.996	0.003
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.996	0.003
T88.2 Shock due to anaesthesia	0.000	0.996	0.003
T88.9 Complication of surgical and medical care, unspecified	0.000	0.997	0.003
C25.9 Pancreas, unspecified	0.000	0.997	0.003
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
I60 Subarachnoid haemorrhage	0.000	0.997	0.003
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.997	0.003
Z63 Other problems related to primary support group, including family circumstances	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.997	0.003
E10.9 Without complications	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.997	0.003
T88.5 Other complications of anaesthesia	0.000	0.997	0.003
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.997	0.003
T88.0 Infection following immunisation	0.000	0.997	0.003
R47.0 Dysphasia and aphasia	0.003	0.997	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.997	0.003
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
Z63.7 Other stressful life events affecting family and household	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.997	0.003
T87.3 Neuroma of amputation stump	0.000	0.997	0.003
T87.5 Necrosis of amputation stump	0.000	0.997	0.003
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.997	0.003
T80.6 Other serum reactions	0.000	0.997	0.003
T80.5 Anaphylactic shock due to serum	0.000	0.997	0.003
T80.4 Rh incompatibility reaction	0.000	0.997	0.003
T80.3 ABO incompatibility reaction	0.000	0.997	0.003
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
T87.6 Other and unspecified complications of amputation stump	0.000	0.997	0.003
T83.2 Mechanical complication of graft of urinary organ	0.000	0.997	0.003
T87.2 Complications of other reattached body part	0.000	0.997	0.003
T87.1 Complications of reattached (part of) lower extremity	0.000	0.997	0.003
T87.0 Complications of reattached (part of) upper extremity	0.000	0.997	0.003
G95 Other diseases of spinal cord	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.003	0.997	0.000
H54.5 Low vision, one eye	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.000	0.997	0.003
T87.4 Infection of amputation stump	0.000	0.997	0.003
T88.4 Failed or difficult intubation	0.000	0.997	0.003
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.997	0.003
Z63.5 Disruption of family by separation and divorce	0.003	0.997	0.000
N60.3 Fibrosclerosis of breast	0.000	0.997	0.003
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.997	0.003
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.997	0.003
I60.8 Other subarachnoid haemorrhage	0.000	0.997	0.003
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.997	0.003
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.997	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.997	0.002
Z63.6 Dependent relative needing care at home	0.003	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.003	0.997	0.000
H54.1 Blindness, one eye, low vision, other eye	0.003	0.997	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.997	0.003
Z63.9 Problem related to primary support group, unspecified	0.003	0.997	0.000
Z63.3 Absence of family member	0.003	0.997	0.000
Z63.2 Inadequate family support	0.003	0.997	0.000
Z63.1 Problems in relationship with parents and in-laws	0.003	0.997	0.000
H54.2 Low vision, both eyes	0.003	0.997	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.003	0.997	0.000
Z63.0 Problems in relationship with spouse or partner	0.003	0.997	0.000
C44.0 Skin of lip	0.000	0.997	0.003
H54.4 Blindness, one eye	0.002	0.997	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.997	0.002
H54.6 Unqualified visual loss, one eye	0.002	0.997	0.000
C44 Other malignant neoplasms of skin	0.000	0.997	0.003
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
I20.0 Unstable angina	0.000	0.998	0.002
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.000	0.998	0.002
C44.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.998	0.002
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
C44.4 Skin of scalp and neck	0.000	0.998	0.002
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.002
C25.3 Pancreatic duct	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
C25.0 Head of pancreas	0.000	0.998	0.002
S70.0 Contusion of hip	0.002	0.998	0.000
E10.4 With neurological complications	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.002	0.998	0.000
S70.1 Contusion of thigh	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.000	0.998	0.002
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
C44.8 Overlapping lesion of skin	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
E10 Insulin-dependent diabetes mellitus	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
C25.2 Tail of pancreas	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.998	0.002
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.998	0.002
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
C15.4 Middle third of oesophagus	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
I06 Rheumatic aortic valve diseases	0.000	0.998	0.002
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.998	0.002
C25.1 Body of pancreas	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.002	0.998	0.000
Y84.6 Urinary catheterisation	0.000	0.998	0.002
E10.0 With coma	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.998	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
Y45.1 Salicylates	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.998	0.002
M81.98 Osteoporosis, unspecified (Other)	0.002	0.998	0.000
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
D50.8 Other iron deficiency anaemias	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.998	0.002
N19 Unspecified renal failure	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
E10.6 With other specified complications	0.002	0.998	0.000
O12.0 Gestational oedema	0.000	0.998	0.002
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.001
I20.1 Angina pectoris with documented spasm	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.998	0.000
E10.8 With unspecified complications	0.002	0.998	0.000
E10.2 With renal complications	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.001
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.001
E10.7 With multiple complications	0.001	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.998	0.000
C21.0 Anus, unspecified	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.998	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.998	0.000
C15.0 Cervical part of oesophagus	0.000	0.998	0.001
C22.9 Liver, unspecified	0.000	0.998	0.002
R26.1 Paralytic gait	0.000	0.998	0.001
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.001
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.001	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.001
S62.21 Fracture of first metacarpal bone (open)	0.001	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
R26.0 Ataxic gait	0.000	0.998	0.001
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.001	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.998	0.000
D47.4 Osteomyelofibrosis	0.001	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.998	0.001
I07.8 Other tricuspid valve diseases	0.000	0.998	0.001
I07.2 Tricuspid stenosis with insufficiency	0.000	0.998	0.001
I07.0 Tricuspid stenosis	0.000	0.998	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.001	0.998	0.000
Q51.3 Bicornate uterus	0.001	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
K51.4 Pseudopolyposis of colon	0.001	0.999	0.000
D68 Other coagulation defects	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
R26.3 Immobility	0.000	0.999	0.001
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.999	0.001
C21 Malignant neoplasm of anus and anal canal	0.000	0.999	0.001
O15 Eclampsia	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
M77.1 Lateral epicondylitis	0.000	0.999	0.001
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.999	0.001
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.001	0.999	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
Z36.9 Antenatal screening, unspecified	0.001	0.999	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.999	0.001
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.001	0.999	0.000
Z36 Antenatal screening	0.001	0.999	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.999	0.001
I64 Stroke, not specified as haemorrhage or infarction	0.001	0.999	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.999	0.001
O36 Maternal care for other known or suspected foetal problems	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.999	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
Z99.3 Dependence on wheelchair	0.000	0.999	0.001
E10.3 With ophthalmic complications	0.001	0.999	0.000
O36.1 Maternal care for other isoimmunisation	0.001	0.999	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.999	0.000
Q51.2 Other doubling of uterus	0.001	0.999	0.000
S09.9 Unspecified injury of head	0.001	0.999	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.999	0.001
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Q51 Congenital malformations of uterus and cervix	0.001	0.999	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.999	0.001
M77.13 Lateral epicondylitis-Forearm	0.000	0.999	0.001
D68.1 Hereditary factor XI deficiency	0.001	0.999	0.000
L91.0 Keloid scar	0.001	0.999	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.001	0.999	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.001	0.999	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.001	0.999	0.000
S83.0 Dislocation of patella	0.001	0.999	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.999	0.001
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.001	0.999	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.999	0.001
C17.9 Small intestine, unspecified	0.000	0.999	0.001
D68.4 Acquired coagulation factor deficiency	0.001	0.999	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.999	0.001
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.999	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.999	0.001
C21.2 Cloacogenic zone	0.000	0.999	0.001
C26.0 Intestinal tract, part unspecified	0.000	0.999	0.001
D68.6 Other Thrombophilia	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.000	0.999	0.001
M77.4 Metatarsalgia	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.000	0.999	0.001
O15.1 Eclampsia in labour	0.000	0.999	0.001
O15.0 Eclampsia in pregnancy	0.000	0.999	0.001
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.999	0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.999	0.001
O42 Premature rupture of membranes	0.001	0.999	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.999	0.001
M77.18 Lateral epicondylitis-Other	0.000	0.999	0.001
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.999	0.001
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.999	0.001
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.999	0.001
M77.14 Lateral epicondylitis-Hand	0.000	0.999	0.001
M77.11 Lateral epicondylitis-Shldr region	0.000	0.999	0.001
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.999	0.001
C21.1 Anal canal	0.000	0.999	0.001
O12.1 Gestational proteinuria	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.999	0.001
S64.4 Injury of digital nerve of other finger	0.001	0.999	0.000
S83.7 Injury to multiple structures of knee	0.001	0.999	0.000
Y44.2 Anticoagulants	0.001	0.999	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.999	0.001
U83 Resistance to other antibiotics	0.000	0.999	0.001
U82 Resistance to betalactam antibiotics	0.000	0.999	0.001
U85 Resistance to antineoplastic drugs	0.000	0.999	0.001
C24.8 Overlapping lesion of biliary tract	0.000	0.999	0.001
G25.0 Essential tremor	0.001	0.999	0.000
G56.2 Lesion of ulnar nerve	0.000	0.999	0.001
O15.2 Eclampsia in the puerperium	0.000	0.999	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
Z36.5 Antenatal screening for isoimmunisation	0.001	0.999	0.000
C17 Malignant neoplasm of small intestine	0.000	0.999	0.001
I78 Diseases of capillaries	0.000	0.999	0.001
L97 Ulcer of lower limb, not elsewhere classified	0.001	0.999	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.999	0.001
O36.2 Maternal care for hydrops foetalis	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
S05.8 Other injuries of eye and orbit	0.001	0.999	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.999	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.999	0.001
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.001	0.999	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.001	0.999	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
S81.0 Open wound of knee	0.000	0.999	0.001
S83.1 Dislocation of knee	0.001	0.999	0.000
C23 Malignant neoplasm of gallbladder	0.000	0.999	0.001
O16 Unspecified maternal hypertension	0.000	0.999	0.001
M77.94 Enthesopathy, unspecified (Hand)	0.000	0.999	0.001
M81.99 Osteoporosis, unspecified (Site unspecified)	0.001	0.999	0.000
C16.8 Overlapping lesion of stomach	0.000	0.999	0.001
I27.0 Primary pulmonary hypertension	0.001	0.999	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000
N83.1 Corpus luteum cyst	0.000	0.999	0.001
O36.9 Maternal care for foetal problem, unspecified	0.001	0.999	0.000
O36.4 Maternal care for intra-uterine death	0.001	0.999	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.999	0.001
S83.3 Tear of articular cartilage of knee, current	0.001	0.999	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.999	0.001
M77.49 Metatarsalgia-Site unspec	0.000	0.999	0.001
M77.48 Metatarsalgia-Other	0.000	0.999	0.001
M77.46 Metatarsalgia-Lower Leg	0.000	0.999	0.001
M77.45 Metatarsalgia-Pelvic/Thigh	0.000	0.999	0.001
M77.44 Metatarsalgia-Hand	0.000	0.999	0.001
M77.43 Metatarsalgia-Forearm	0.000	0.999	0.001
M77.42 Metatarsalgia-Upper arm	0.000	0.999	0.001
M77.41 Metatarsalgia-Shldr region	0.000	0.999	0.001
M77.40 Metatarsalgia-Mult sites	0.000	0.999	0.001
C22.7 Other specified carcinomas of liver	0.000	0.999	0.001
C22.4 Other sarcomas of liver	0.000	0.999	0.001
C22.3 Angiosarcoma of liver	0.000	0.999	0.001
C22.2 Hepatoblastoma	0.000	0.999	0.001
C26.8 Overlapping lesion of digestive system	0.000	0.999	0.001
C26.1 Spleen	0.000	0.999	0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.999	0.000
N60.2 Fibroadenosis of breast	0.000	0.999	0.001
O14.2 HELLP syndrome	0.000	0.999	0.001
O14.1 Severe preeclampsia	0.000	0.999	0.001
S62.6 Fracture of other finger	0.001	0.999	0.000
Y84.8 Other medical procedures	0.000	0.999	0.001
Z43.1 Attention to gastrostomy	0.000	0.999	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
C24.9 Biliary tract, unspecified	0.000	0.999	0.001
C24.1 Ampulla of Vater	0.000	0.999	0.001
C26.9 Ill-defined sites within the digestive system	0.000	0.999	0.001
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.999	0.001
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.999	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.999	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.999	0.001
U82.1 Resistance to methicillin	0.000	0.999	0.001
U82.0 Resistance to penicillin	0.000	0.999	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.999	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.999	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.999	0.001
U83.2 Resistance to quinolones	0.000	0.999	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.999	0.001
U83.0 Resistance to vancomycin	0.000	0.999	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.999	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.999	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.999	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.999	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.999	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.999	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.999	0.001
I05 Rheumatic mitral valve diseases	0.000	0.999	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.999	0.001
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
C17.8 Overlapping lesion of small intestine	0.000	0.999	0.001
C17.3 Meckel's diverticulum	0.000	0.999	0.001
H47.3 Other disorders of optic disk	0.001	0.999	0.000
I07.1 Tricuspid insufficiency	0.000	0.999	0.001
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.999	0.000
I61.8 Other intracerebral haemorrhage	0.001	0.999	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
Y84.0 Cardiac catheterisation	0.000	0.999	0.001
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.001	0.999	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
S22.01 Fracture of thoracic vertebra (open)	0.000	0.999	0.001
K51.0 Ulcerative (chronic) enterocolitis	0.001	0.999	0.000
M11.2 Other chondrocalcinosis	0.000	0.999	0.001
O14.9 Preeclampsia, unspecified	0.000	0.999	0.001
S02.1 Fracture of base of skull	0.000	0.999	0.001
C16.5 Lesser curvature of stomach, unspecified	0.000	0.999	0.001
C17.2 Ileum	0.000	0.999	0.001
C17.1 Jejunum	0.000	0.999	0.001
D04.3 Skin of other and unspecified parts of face	0.001	0.999	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations