TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs209126
log Bayes Factor = 53.8367
Chromosome 6   position 28,872,446  (GRCh37) Explore rs209126 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.004 0.996
E00-E07 Disorders of thyroid gland
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.045 0.955
E10.2 With renal complications
0.000 0.047 0.953
E10.1 With ketoacidosis
0.000 0.099 0.901
E10.4 With neurological complications
0.000 0.102 0.898
E05.8 Other thyrotoxicosis
0.000 0.186 0.814
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.811 0.189 0.000
E13 Other specified diabetes mellitus
0.000 0.191 0.809
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.209 0.791
E16.1 Other hypoglycaemia
0.000 0.220 0.780
E10.7 With multiple complications
0.000 0.251 0.749
E10.0 With coma
0.000 0.251 0.749
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.286 0.714
E00 Congenital iodine-deficiency syndrome
0.000 0.286 0.714
E40-E46 Malnutrition
0.000 0.309 0.691
E10.5 With peripheral circulatory complications
0.000 0.326 0.674
E13.9 Without complications
0.000 0.330 0.670
E14 Unspecified diabetes mellitus
0.000 0.331 0.669
E07 Other disorders of thyroid
0.000 0.352 0.648
E10.6 With other specified complications
0.000 0.361 0.638
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.363 0.637
E13.3 With ophthalmic complications
0.000 0.416 0.584
E13.8 With unspecified complications
0.000 0.420 0.580
E13.7 With multiple complications
0.000 0.420 0.580
E13.6 With other specified complications
0.000 0.420 0.580
E13.5 With peripheral circulatory complications
0.000 0.420 0.580
E13.4 With neurological complications
0.000 0.420 0.580
E13.2 With renal complications
0.000 0.420 0.580
E13.1 With ketoacidosis
0.000 0.420 0.580
E13.0 With coma
0.000 0.420 0.580
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.425 0.575
E06 Thyroiditis
0.000 0.439 0.561
E14.3 With ophthalmic complications
0.000 0.444 0.556
E14.1 With ketoacidosis
0.000 0.460 0.540
E07.8 Other specified disorders of thyroid
0.000 0.471 0.529
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.488 0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.488 0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.488 0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.488 0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.488 0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.488 0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.488 0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.488 0.512
E14.6 With other specified complications
0.000 0.491 0.509
E10.8 With unspecified complications
0.000 0.492 0.508
E14.4 With neurological complications
0.000 0.502 0.498
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.504 0.495
E45 Retarded development following protein-energy malnutrition
0.000 0.504 0.495
E43 Unspecified severe protein-energy malnutrition
0.000 0.504 0.495
E42 Marasmic kwashiorkor
0.000 0.504 0.495
E41 Nutritional marasmus
0.000 0.504 0.495
E40 Kwashiorkor
0.000 0.504 0.495
E14.8 With unspecified complications
0.000 0.515 0.485
E14.7 With multiple complications
0.000 0.520 0.480
E46 Unspecified protein-energy malnutrition
0.000 0.529 0.471
E07.1 Dyshormogenetic goitre
0.000 0.535 0.464
E07.0 Hypersecretion of calcitonin
0.000 0.535 0.464
E14.2 Withrenal complications
0.000 0.542 0.458
E14.5 With peripheral circulatory complications
0.000 0.547 0.453
E14.0 With coma
0.000 0.551 0.449
E06.9 Thyroiditis, unspecified
0.000 0.559 0.441
E03 Other hypothyroidism
0.000 0.575 0.425
E06.1 Subacute thyroiditis
0.000 0.578 0.421
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.588 0.412
E06.4 Drug-induced thyroiditis
0.000 0.598 0.402
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.598 0.402
E06.0 Acute thyroiditis
0.000 0.598 0.402
E06.5 Other chronic thyroiditis
0.000 0.614 0.386
E50-E64 Other nutritional deficiencies
0.000 0.641 0.359
E11 Non-insulin-dependent diabetes mellitus
0.000 0.641 0.359
E44.1 Mild protein-energy malnutrition
0.000 0.644 0.355
E44.0 Moderate protein-energy malnutrition
0.000 0.644 0.355
K90 Intestinal malabsorption
0.000 0.650 0.349
E11.6 With other specified complications
0.000 0.673 0.327
E65-E68 Obesity and other hyperalimentation
0.000 0.675 0.325
E70-E90 Metabolic disorders
0.001 0.679 0.320
I73 Other peripheral vascular diseases
0.000 0.681 0.319
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.681 0.319
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.682 0.318
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.683 0.317
I73.9 Peripheral vascular disease, unspecified
0.000 0.683 0.317
I77 Other disorders of arteries and arterioles
0.000 0.685 0.315
E11.1 With ketoacidosis
0.000 0.685 0.315
E78.2 Mixed hyperlipidaemia
0.000 0.692 0.308
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.695 0.305
E03.5 Myxoedema coma
0.000 0.695 0.305
E03.4 Atrophy of thyroid (acquired)
0.000 0.695 0.305
E03.3 Postinfectious hypothyroidism
0.000 0.695 0.305
I74 Arterial embolism and thrombosis
0.000 0.699 0.301
I77.6 Arteritis, unspecified
0.000 0.701 0.299
E03.1 Congenital hypothyroidism without goitre
0.000 0.706 0.293
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.708 0.292
I72 Other aneurysm
0.000 0.708 0.292
E11.0 With coma
0.000 0.711 0.289
E78.5 Hyperlipidaemia, unspecified
0.000 0.711 0.289
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.713 0.287
I73.0 Raynaud's syndrome
0.000 0.717 0.283
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.717 0.283
I74.5 Embolism and thrombosis of iliac artery
0.000 0.720 0.280
E78.1 Pure hyperglyceridaemia
0.000 0.721 0.279
E11.2 With renal complications
0.000 0.723 0.277
I77.8 Other specified disorders of arteries and arterioles
0.000 0.731 0.269
E07.9 Disorder of thyroid, unspecified
0.000 0.736 0.263
E54 Ascorbic acid deficiency
0.000 0.738 0.261
E03.8 Other specified hypothyroidism
0.000 0.741 0.259
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.742 0.257
E63 Other nutritional deficiencies
0.000 0.742 0.257
E50 Vitamin A deficiency
0.000 0.742 0.257
E60 Dietary zinc deficiency
0.000 0.742 0.257
E59 Dietary selenium deficiency
0.000 0.742 0.257
E52 Niacin deficiency [pellagra]
0.000 0.742 0.257
E11.7 With multiple complications
0.000 0.743 0.257
E88 Other metabolic disorders
0.000 0.743 0.257
I70 Atherosclerosis
0.000 0.743 0.257
E51 Thiamine deficiency
0.000 0.744 0.256
E78.6 Lipoprotein deficiency
0.000 0.744 0.256
I72.4 Aneurysm of artery of lower extremity
0.000 0.744 0.256
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.745 0.255
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.749 0.251
K90.3 Pancreatic steatorrhoea
0.000 0.749 0.251
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.749 0.251
K90.1 Tropical sprue
0.000 0.749 0.251
E74 Other disorders of carbohydrate metabolism
0.001 0.754 0.245
E56 Other vitamin deficiencies
0.000 0.757 0.243
I73.8 Other specified peripheral vascular diseases
0.000 0.757 0.243
I72.3 Aneurysm of iliac artery
0.000 0.758 0.242
E78.3 Hyperchylomicronaemia
0.000 0.759 0.241
K90.8 Other intestinal malabsorption
0.000 0.760 0.239
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.761 0.239
I77.3 Arterial fibromuscular dysplasia
0.000 0.762 0.238
I77.1 Stricture of artery
0.000 0.764 0.236
E58 Dietary calcium deficiency
0.000 0.765 0.235
E67 Other hyperalimentation
0.000 0.767 0.233
E68 Sequelae of hyperalimentation
0.000 0.767 0.233
E84 Cystic fibrosis
0.001 0.767 0.232
E83 Disorders of mineral metabolism
0.147 0.768 0.085
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.769 0.231
E77 Disorders of glycoprotein metabolism
0.001 0.770 0.230
E76 Disorders of glycosaminoglycan metabolism
0.001 0.770 0.230
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.770 0.230
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.770 0.230
E85 Amyloidosis
0.001 0.770 0.229
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.771 0.229
E55 Vitamin D deficiency
0.000 0.771 0.229
E73 Lactose intolerance
0.001 0.772 0.227
I77.2 Rupture of artery
0.000 0.772 0.228
I72.1 Aneurysm of artery of upper extremity
0.000 0.774 0.226
I77.5 Necrosis of artery
0.000 0.774 0.226
I77.4 Coeliac artery compression syndrome
0.000 0.774 0.226
E88.9 Metabolic disorder, unspecified
0.000 0.778 0.222
I72.0 Aneurysm of carotid artery
0.000 0.778 0.221
E70 Disorders of aromatic amino-acid metabolism
0.001 0.781 0.218
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.784 0.216
E79 Disorders of purine and pyrimidine metabolism
0.001 0.785 0.214
E78.4 Other hyperlipidaemia
0.000 0.786 0.214
E11.8 With unspecified complications
0.000 0.788 0.212
E61 Deficiency of other nutrient elements
0.000 0.788 0.211
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.789 0.211
I72.2 Aneurysm of renal artery
0.000 0.790 0.209
E72 Other disorders of amino-acid metabolism
0.001 0.791 0.209
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.791 0.209
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.791 0.209
I72.9 Aneurysm of unspecified site
0.000 0.794 0.206
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.795 0.205
E88.2 Lipomatosis, not elsewhere classified
0.000 0.798 0.202
E75.5 Other lipid storage disorders
0.000 0.801 0.199
E78.0 Pure hypercholesterolaemia
0.000 0.802 0.198
I70.1 Atherosclerosis of renal artery
0.000 0.803 0.197
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.804 0.196
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.805 0.195
I70.8 Atherosclerosis of other arteries
0.000 0.806 0.194
I72.8 Aneurysm of other specified arteries
0.000 0.807 0.193
E85.4 Organ-limited amyloidosis
0.000 0.811 0.189
M45.X9 Ankylosing spondylitis (Site unspecified)
0.189 0.811 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.815 0.185
E50.8 Other manifestations of vitamin A deficiency
0.000 0.815 0.185
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.815 0.185
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.815 0.185
E50.5 Vitamin A deficiency with night blindness
0.000 0.815 0.185
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.815 0.185
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.815 0.185
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.815 0.185
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.815 0.185
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.815 0.185
E63.9 Nutritional deficiency, unspecified
0.000 0.815 0.185
E63.8 Other specified nutritional deficiencies
0.000 0.815 0.185
E63.1 Imbalance of constituents of food intake
0.000 0.815 0.185
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.815 0.185
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.815 0.185
E64.8 Sequelae of other nutritional deficiencies
0.000 0.815 0.185
E64.3 Sequelae of rickets
0.000 0.815 0.185
E64.2 Sequelae of vitamin C deficiency
0.000 0.815 0.185
E64.1 Sequelae of vitamin A deficiency
0.000 0.815 0.185
E64.0 Sequelae of protein-energy malnutrition
0.000 0.815 0.185
E51.9 Thiamine deficiency, unspecified
0.000 0.816 0.184
E51.8 Other manifestations of thiamine deficiency
0.000 0.816 0.184
E51.1 Beriberi
0.000 0.816 0.184
I83 Varicose veins of lower extremities
0.184 0.816 0.000
E75.2 Other sphingolipidosis
0.001 0.817 0.183
E51.2 Wernicke's encephalopathy
0.000 0.817 0.183
E75.6 Lipid storage disorder, unspecified
0.001 0.820 0.180
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.820 0.180
E75.3 Sphingolipidosis, unspecified
0.001 0.820 0.180
E75.1 Other gangliosidosis
0.001 0.820 0.180
E75.0 GM2 gangliosidosis
0.001 0.820 0.180
I70.9 Generalised and unspecified atherosclerosis
0.000 0.821 0.179
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.821 0.179
E53 Deficiency of other B group vitamins
0.000 0.822 0.178
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.823 0.177
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.824 0.176
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.824 0.176
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.824 0.176
E74.2 Disorders of galactose metabolism
0.001 0.824 0.176
E74.1 Disorders of fructose metabolism
0.001 0.824 0.176
I70.0 Atherosclerosis of aorta
0.000 0.824 0.176
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.825 0.175
E65 Localised adiposity
0.000 0.825 0.175
E56.9 Vitamin deficiency, unspecified
0.000 0.825 0.174
E56.8 Deficiency of other vitamins
0.000 0.825 0.174
E56.0 Deficiency of vitamin E
0.000 0.825 0.174
E88.8 Other specified metabolic disorders
0.000 0.827 0.173
E85.3 Secondary systemic amyloidosis
0.000 0.827 0.172
I79.1 Aortitis in diseases classified elsewhere
0.000 0.828 0.172
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.828 0.172
E74.0 Glycogen storage disease
0.001 0.829 0.171
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.829 0.171
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.829 0.170
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.831 0.169
E67.8 Other specified hyperalimentation
0.000 0.832 0.167
E67.3 Hypervitaminosis D
0.000 0.832 0.167
E67.2 Megavitamin-B6 syndrome
0.000 0.832 0.167
E67.1 Hypercarotenaemia
0.000 0.832 0.167
E67.0 Hypervitaminosis A
0.000 0.832 0.167
E84.8 Cystic fibrosis with other manifestations
0.001 0.833 0.166
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.833 0.166
E85.8 Other amyloidosis
0.001 0.833 0.166
E83.8 Other disorders of mineral metabolism
0.105 0.834 0.061
E83.2 Disorders of zinc metabolism
0.105 0.834 0.061
E83.0 Disorders of copper metabolism
0.105 0.834 0.061
E84.9 Cystic fibrosis, unspecified
0.001 0.834 0.165
E71.3 Disorders of fatty-acid metabolism
0.001 0.835 0.165
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.835 0.165
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.835 0.165
E71.0 Maple-syrup-urine disease
0.001 0.835 0.165
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.835 0.165
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.835 0.165
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.835 0.165
E76.2 Other mucopolysaccharidoses
0.001 0.835 0.165
E76.1 Mucopolysaccharidosis, type II
0.001 0.835 0.165
E76.0 Mucopolysaccharidosis, type I
0.001 0.835 0.165
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.835 0.165
E77.8 Other disorders of glycoprotein metabolism
0.001 0.835 0.165
E77.1 Defects in glycoprotein degradation
0.001 0.835 0.165
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.835 0.165
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.835 0.165
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.835 0.165
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.835 0.165
E83.9 Disorder of mineral metabolism, unspecified
0.105 0.836 0.059
E55.0 Rickets, active
0.000 0.836 0.164
E73.8 Other lactose intolerance
0.001 0.836 0.163
E73.1 Secondary lactase deficiency
0.001 0.836 0.163
E73.0 Congenital lactase deficiency
0.001 0.836 0.163
K90.9 Intestinal malabsorption, unspecified
0.000 0.837 0.163
E73.9 Lactose intolerance, unspecified
0.000 0.839 0.161
E56.1 Deficiency of vitamin K
0.000 0.840 0.160
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.843 0.156
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.843 0.156
E70.2 Disorders of tyrosine metabolism
0.001 0.843 0.156
E70.1 Other hyperphenylalaninaemias
0.001 0.843 0.156
E70.0 Classical phenylketonuria
0.001 0.843 0.156
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.846 0.154
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.846 0.154
E79.1 Lesch-Nyhan syndrome
0.001 0.846 0.154
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.846 0.154
E61.9 Deficiency of nutrient element, unspecified
0.000 0.848 0.152
E61.8 Deficiency of other specified nutrient elements
0.000 0.848 0.152
E61.7 Deficiency of multiple nutrient elements
0.000 0.848 0.152
E61.6 Vanadium deficiency
0.000 0.848 0.152
E61.5 Molybdenum deficiency
0.000 0.848 0.152
E61.4 Chromium deficiency
0.000 0.848 0.152
E61.3 Manganese deficiency
0.000 0.848 0.152
E61.0 Copper deficiency
0.000 0.848 0.152
I78 Diseases of capillaries
0.000 0.848 0.152
E88.3 Tumour lysis syndrome
0.000 0.848 0.151
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.850 0.150
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.850 0.150
E72.5 Disorders of glycine metabolism
0.001 0.850 0.150
E72.4 Disorders of ornithine metabolism
0.001 0.850 0.150
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.850 0.150
E72.2 Disorders of urea cycle metabolism
0.001 0.850 0.150
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.851 0.149
E72.0 Disorders of amino-acid transport
0.001 0.854 0.145
E70.3 Albinism
0.001 0.855 0.144
E11.5 With peripheral circulatory complications
0.000 0.855 0.145
E78.8 Other disorders of lipoprotein metabolism
0.000 0.855 0.145
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.857 0.142
E83.3 Disorders of phosphorus metabolism
0.118 0.858 0.025
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.859 0.141
E61.2 Magnesium deficiency
0.000 0.859 0.141
E14.9 Without complications
0.000 0.860 0.140
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.861 0.139
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.861 0.138
I77.0 Arteriovenous fistula, acquired
0.000 0.862 0.137
E06.3 Autoimmune thyroiditis
0.001 0.865 0.135
E55.9 Vitamin D deficiency, unspecified
0.000 0.865 0.135
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.865 0.134
E20-E35 Disorders of other endocrine glands
0.000 0.867 0.133
E53.9 Vitamin B deficiency, unspecified
0.000 0.869 0.130
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.870 0.130
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.871 0.128
E53.1 Pyridoxine deficiency
0.000 0.872 0.127
E53.0 Riboflavin deficiency
0.000 0.872 0.127
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.873 0.126
I83.0 Varicose veins of lower extremities with ulcer
0.125 0.875 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.876 0.124
I74.8 Embolism and thrombosis of other arteries
0.001 0.877 0.123
E61.1 Iron deficiency
0.000 0.878 0.122
I74.9 Embolism and thrombosis of unspecified artery
0.001 0.878 0.121
E03.9 Hypothyroidism, unspecified
0.000 0.879 0.121
E24 Cushing's syndrome
0.000 0.880 0.120
E11.3 With ophthalmic complications
0.000 0.880 0.120
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.881 0.119
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.882 0.117
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.114 0.886 0.000
E85.9 Amyloidosis, unspecified
0.001 0.890 0.109
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.892 0.108
I78.8 Other diseases of capillaries
0.000 0.895 0.105
E24.9 Cushing's syndrome, unspecified
0.000 0.897 0.103
E21.3 Hyperparathyroidism, unspecified
0.000 0.899 0.101
E24.0 Pituitary-dependent Cushing's disease
0.000 0.900 0.100
E20 Hypoparathyroidism
0.000 0.901 0.099
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.905 0.095
E32 Diseases of thymus
0.000 0.905 0.095
E30 Disorders of puberty, not elsewhere classified
0.000 0.905 0.095
E25 Adrenogenital disorders
0.000 0.905 0.095
E11.4 With neurological complications
0.000 0.905 0.095
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.906 0.094
E31 Polyglandular dysfunction
0.000 0.906 0.094
M45 Ankylosing spondylitis
0.093 0.907 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.909 0.091
E80.2 Other porphyria
0.001 0.910 0.089
E28 Ovarian dysfunction
0.000 0.911 0.089
E24.8 Other Cushing's syndrome
0.000 0.913 0.086
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.913 0.086
E24.3 Ectopic ACTH syndrome
0.000 0.913 0.086
E24.1 Nelson's syndrome
0.000 0.913 0.086
E83.4 Disorders of magnesium metabolism
0.047 0.914 0.039
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.915 0.084
E80.5 Crigler-Najjar syndrome
0.001 0.915 0.084
E80.3 Defects of catalase and peroxydase
0.001 0.915 0.084
E80.0 Hereditary erythropoietic porphyria
0.001 0.915 0.084
I78.9 Disease of capillaries, unspecified
0.000 0.916 0.083
E29 Testicular dysfunction
0.000 0.918 0.082
E21.2 Other hyperparathyroidism
0.000 0.922 0.077
E21.4 Other specified disorders of parathyroid gland
0.000 0.923 0.077
E20.9 Hypoparathyroidism, unspecified
0.000 0.924 0.076
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.924 0.075
E34 Other endocrine disorders
0.000 0.926 0.074
M45.X2 Ankylosing spondylitis (Cervical region)
0.073 0.927 0.000
E80.6 Other disorders of bilirubin metabolism
0.001 0.928 0.071
E20.8 Other hypoparathyroidism
0.000 0.928 0.071
E20.1 Pseudohypoparathyroidism
0.000 0.928 0.071
E20.0 Idiopathic hypoparathyroidism
0.000 0.928 0.071
E80.1 Porphyria cutanea tarda
0.001 0.930 0.069
M45.X6 Ankylosing spondylitis (Lumbar region)
0.069 0.931 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.931 0.068
E30.8 Other disorders of puberty
0.000 0.931 0.068
E30.1 Precocious puberty
0.000 0.931 0.068
E30.0 Delayed puberty
0.000 0.931 0.068
E32.9 Disease of thymus, unspecified
0.000 0.931 0.068
E32.8 Other diseases of thymus
0.000 0.931 0.068
E32.1 Abscess of thymus
0.000 0.931 0.068
E32.0 Persistent hyperplasia of thymus
0.000 0.931 0.068
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.931 0.068
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.931 0.068
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.931 0.068
E25.9 Adrenogenital disorder, unspecified
0.000 0.932 0.068
E25.8 Other adrenogenital disorders
0.000 0.932 0.068
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.932 0.068
E31.9 Polyglandular dysfunction, unspecified
0.000 0.933 0.067
E31.8 Other polyglandular dysfunction
0.000 0.933 0.067
E31.1 Polyglandular hyperfunction
0.000 0.933 0.067
E83.5 Disorders of calcium metabolism
0.005 0.933 0.062
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.066 0.933 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.066 0.933 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.066 0.933 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.066 0.933 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.066 0.933 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.066 0.933 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.934 0.065
E28.9 Ovarian dysfunction, unspecified
0.000 0.936 0.064
E28.8 Other ovarian dysfunction
0.000 0.936 0.064
E28.1 Androgen excess
0.000 0.936 0.064
E28.0 Oestrogen excess
0.000 0.936 0.064
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.937 0.063
E26 Hyperaldosteronism
0.000 0.937 0.062
E28.2 Polycystic ovarian syndrome
0.000 0.939 0.061
E28.3 Primary ovarian failure
0.000 0.940 0.060
E29.9 Testicular dysfunction, unspecified
0.000 0.940 0.060
I83.1 Varicose veins of lower extremities with inflammation
0.060 0.940 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.059 0.941 0.000
E29.8 Other testicular dysfunction
0.000 0.941 0.059
E29.0 Testicular hyperfunction
0.000 0.941 0.059
E21.0 Primary hyperparathyroidism
0.000 0.944 0.056
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.055 0.945 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.054 0.946 0.000
I86 Varicose veins of other sites
0.054 0.946 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.946 0.054
E34.5 Androgen resistance syndrome
0.000 0.946 0.053
E34.4 Constitutional tall stature
0.000 0.946 0.053
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.946 0.053
E34.1 Other hypersecretion of intestinal hormones
0.000 0.946 0.053
E22 Hyperfunction of pituitary gland
0.000 0.949 0.051
E34.8 Other specified endocrine disorders
0.000 0.950 0.050
I89.0 Lymphoedema, not elsewhere classified
0.050 0.950 0.000
I86.8 Varicose veins of other specified sites
0.049 0.951 0.000
I81 Portal vein thrombosis
0.049 0.951 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.049 0.951 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.951 0.049
I86.4 Gastric varices
0.048 0.952 0.000
E04 Other non-toxic goitre
0.001 0.955 0.044
E26.8 Other hyperaldosteronism
0.000 0.955 0.045
E26.1 Secondary hyperaldosteronism
0.000 0.955 0.045
I85 Oesophageal varices
0.045 0.955 0.000
E34.0 Carcinoid syndrome
0.000 0.956 0.044
E29.1 Testicular hypofunction
0.000 0.956 0.044
E11.9 Without complications
0.000 0.956 0.044
E23 Hypofunction and other disorders of pituitary gland
0.000 0.957 0.042
I89.1 Lymphangitis
0.041 0.959 0.000
I86.3 Vulval varices
0.040 0.959 0.000
I86.2 Pelvic varices
0.040 0.960 0.000
I82 Other venous embolism and thrombosis
0.040 0.960 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.960 0.039
I86.0 Sublingual varices
0.039 0.961 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.961 0.039
I85.9 Oesophageal varices without bleeding
0.038 0.962 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.963 0.037
E23.7 Disorder of pituitary gland, unspecified
0.000 0.963 0.037
I87 Other disorders of veins
0.036 0.964 0.000
E22.1 Hyperprolactinaemia
0.000 0.965 0.035
E86 Volume depletion
0.000 0.965 0.035
I88 Nonspecific lymphadenitis
0.035 0.965 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.965 0.035
E04.8 Other specified non-toxic goitre
0.001 0.967 0.032
I82.8 Embolism and thrombosis of other specified veins
0.032 0.968 0.000
E80.4 Gilbert's syndrome
0.001 0.969 0.031
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.969 0.031
E23.1 Drug-induced hypopituitarism
0.000 0.969 0.031
I82.0 Budd-Chiari syndrome
0.031 0.969 0.000
E66 Obesity
0.000 0.970 0.030
I82.1 Thrombophlebitis migrans
0.029 0.971 0.000
I87.8 Other specified disorders of veins
0.028 0.972 0.000
I82.3 Embolism and thrombosis of renal vein
0.027 0.973 0.000
I82.2 Embolism and thrombosis of vena cava
0.027 0.973 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.973 0.027
R31 Unspecified haematuria
0.027 0.973 0.000
I85.0 Oesophageal varices with bleeding
0.027 0.973 0.000
I87.0 Postphlebitic syndrome
0.026 0.974 0.000
I87.9 Disorder of vein, unspecified
0.026 0.974 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.974 0.026
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.001 0.975 0.024
C15-C26 Malignant neoplasms of digestive organs
0.000 0.975 0.025
C20 Malignant neoplasm of rectum
0.000 0.975 0.025
I88.1 Chronic lymphadenitis, except mesenteric
0.025 0.975 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.975 0.025
E26.0 Primary hyperaldosteronism
0.001 0.976 0.023
I88.8 Other nonspecific lymphadenitis
0.024 0.976 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.023 0.977 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.977 0.022

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.