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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs209148
log Bayes Factor = 53.4582
Chromosome 6   position 28,857,269  (GRCh37) Explore rs209148 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.043 0.957
E10.2 With renal complications
0.000 0.048 0.952
E10.1 With ketoacidosis
0.000 0.078 0.922
E10.4 With neurological complications
0.000 0.117 0.883
E05.8 Other thyrotoxicosis
0.000 0.187 0.813
E13 Other specified diabetes mellitus
0.000 0.208 0.792
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.211 0.789
E16.1 Other hypoglycaemia
0.000 0.222 0.778
E10.7 With multiple complications
0.000 0.251 0.749
E10.0 With coma
0.000 0.279 0.720
E05.5 Thyroid crisis or storm
0.000 0.284 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.715
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.286 0.714
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.286 0.714
E16.4 Abnormal secretion of gastrin
0.000 0.286 0.714
E16.3 Increased secretion of glucagon
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.706 0.294 0.000
E40-E46 Malnutrition
0.000 0.311 0.689
E10.5 With peripheral circulatory complications
0.000 0.328 0.672
E10.6 With other specified complications
0.000 0.332 0.668
E14 Unspecified diabetes mellitus
0.000 0.333 0.667
E13.9 Without complications
0.000 0.344 0.656
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.363 0.636
E07 Other disorders of thyroid
0.000 0.396 0.604
E06 Thyroiditis
0.000 0.413 0.587
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.573
E13.8 With unspecified complications
0.000 0.432 0.568
E13.7 With multiple complications
0.000 0.432 0.568
E13.6 With other specified complications
0.000 0.432 0.568
E13.5 With peripheral circulatory complications
0.000 0.432 0.568
E13.4 With neurological complications
0.000 0.432 0.568
E13.2 With renal complications
0.000 0.432 0.568
E13.1 With ketoacidosis
0.000 0.432 0.568
E13.0 With coma
0.000 0.432 0.568
E14.3 With ophthalmic complications
0.000 0.446 0.554
E13.3 With ophthalmic complications
0.000 0.448 0.552
E14.1 With ketoacidosis
0.000 0.462 0.538
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E10.8 With unspecified complications
0.000 0.493 0.507
E14.6 With other specified complications
0.000 0.493 0.507
E14.4 With neurological complications
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
E14.8 With unspecified complications
0.000 0.516 0.483
E14.7 With multiple complications
0.000 0.522 0.478
E07.8 Other specified disorders of thyroid
0.000 0.523 0.477
E06.9 Thyroiditis, unspecified
0.000 0.526 0.474
E46 Unspecified protein-energy malnutrition
0.000 0.531 0.469
E14.2 Withrenal complications
0.000 0.544 0.456
E14.5 With peripheral circulatory complications
0.000 0.549 0.451
E14.0 With coma
0.000 0.552 0.448
E06.1 Subacute thyroiditis
0.000 0.559 0.441
E07.1 Dyshormogenetic goitre
0.000 0.567 0.433
E07.0 Hypersecretion of calcitonin
0.000 0.567 0.433
E06.4 Drug-induced thyroiditis
0.000 0.579 0.421
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.579 0.421
E06.0 Acute thyroiditis
0.000 0.579 0.421
K90 Intestinal malabsorption
0.000 0.586 0.414
E06.5 Other chronic thyroiditis
0.000 0.596 0.404
E03 Other hypothyroidism
0.000 0.600 0.400
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.617 0.383
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.354
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.649 0.351
E65-E68 Obesity and other hyperalimentation
0.000 0.677 0.323
E11 Non-insulin-dependent diabetes mellitus
0.000 0.678 0.322
E50-E64 Other nutritional deficiencies
0.000 0.680 0.319
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.701 0.299
K90.3 Pancreatic steatorrhoea
0.000 0.703 0.297
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.703 0.297
K90.1 Tropical sprue
0.000 0.703 0.297
E11.6 With other specified complications
0.000 0.708 0.292
E03.5 Myxoedema coma
0.000 0.713 0.287
E03.4 Atrophy of thyroid (acquired)
0.000 0.713 0.287
E03.3 Postinfectious hypothyroidism
0.000 0.713 0.287
K90.8 Other intestinal malabsorption
0.000 0.717 0.283
E11.1 With ketoacidosis
0.000 0.719 0.281
E03.1 Congenital hypothyroidism without goitre
0.000 0.724 0.276
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.725 0.275
E11.0 With coma
0.000 0.734 0.266
E03.8 Other specified hypothyroidism
0.000 0.756 0.244
E11.2 With renal complications
0.000 0.760 0.240
E54 Ascorbic acid deficiency
0.000 0.767 0.233
E67 Other hyperalimentation
0.000 0.768 0.232
E68 Sequelae of hyperalimentation
0.000 0.768 0.232
E11.7 With multiple complications
0.000 0.769 0.231
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.771 0.229
E63 Other nutritional deficiencies
0.000 0.771 0.229
E50 Vitamin A deficiency
0.000 0.771 0.229
E60 Dietary zinc deficiency
0.000 0.771 0.229
E59 Dietary selenium deficiency
0.000 0.771 0.229
E52 Niacin deficiency [pellagra]
0.000 0.771 0.229
E07.9 Disorder of thyroid, unspecified
0.000 0.772 0.228
E51 Thiamine deficiency
0.000 0.772 0.228
E56 Other vitamin deficiencies
0.000 0.784 0.216
E83 Disorders of mineral metabolism
0.181 0.785 0.034
E55 Vitamin D deficiency
0.000 0.793 0.207
M45.X9 Ankylosing spondylitis (Site unspecified)
0.203 0.797 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.798 0.202
E58 Dietary calcium deficiency
0.000 0.801 0.199
E11.8 With unspecified complications
0.000 0.819 0.181
E61 Deficiency of other nutrient elements
0.000 0.825 0.175
E65 Localised adiposity
0.000 0.827 0.173
E67.8 Other specified hyperalimentation
0.000 0.833 0.166
E67.3 Hypervitaminosis D
0.000 0.833 0.166
E67.2 Megavitamin-B6 syndrome
0.000 0.833 0.166
E67.1 Hypercarotenaemia
0.000 0.833 0.166
E67.0 Hypervitaminosis A
0.000 0.833 0.166
E50.9 Vitamin A deficiency, unspecified
0.000 0.835 0.164
E50.8 Other manifestations of vitamin A deficiency
0.000 0.835 0.164
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.835 0.164
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.835 0.164
E50.5 Vitamin A deficiency with night blindness
0.000 0.835 0.164
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.835 0.164
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.835 0.164
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.835 0.164
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.835 0.164
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.835 0.164
E63.9 Nutritional deficiency, unspecified
0.000 0.835 0.164
E63.8 Other specified nutritional deficiencies
0.000 0.835 0.164
E63.1 Imbalance of constituents of food intake
0.000 0.835 0.164
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.835 0.164
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.835 0.164
E64.8 Sequelae of other nutritional deficiencies
0.000 0.835 0.164
E64.3 Sequelae of rickets
0.000 0.835 0.164
E64.2 Sequelae of vitamin C deficiency
0.000 0.835 0.164
E64.1 Sequelae of vitamin A deficiency
0.000 0.835 0.164
E64.0 Sequelae of protein-energy malnutrition
0.000 0.835 0.164
E83.3 Disorders of phosphorus metabolism
0.156 0.836 0.008
E51.9 Thiamine deficiency, unspecified
0.000 0.836 0.163
E51.8 Other manifestations of thiamine deficiency
0.000 0.836 0.163
E51.1 Beriberi
0.000 0.836 0.163
E51.2 Wernicke's encephalopathy
0.000 0.838 0.162
E70-E90 Metabolic disorders
0.002 0.840 0.159
E53 Deficiency of other B group vitamins
0.000 0.843 0.157
E56.9 Vitamin deficiency, unspecified
0.000 0.845 0.155
E56.8 Deficiency of other vitamins
0.000 0.845 0.155
E56.0 Deficiency of vitamin E
0.000 0.845 0.155
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.845 0.155
E83.8 Other disorders of mineral metabolism
0.130 0.846 0.025
E83.2 Disorders of zinc metabolism
0.130 0.846 0.025
E83.0 Disorders of copper metabolism
0.130 0.846 0.025
E83.9 Disorder of mineral metabolism, unspecified
0.130 0.847 0.024
E78.2 Mixed hyperlipidaemia
0.000 0.849 0.151
E55.0 Rickets, active
0.000 0.851 0.148
E06.3 Autoimmune thyroiditis
0.001 0.852 0.148
E14.9 Without complications
0.000 0.855 0.145
E11.5 With peripheral circulatory complications
0.000 0.856 0.143
I83 Varicose veins of lower extremities
0.142 0.858 0.000
E56.1 Deficiency of vitamin K
0.000 0.858 0.142
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.863 0.137
E78.1 Pure hyperglyceridaemia
0.000 0.864 0.135
E78.5 Hyperlipidaemia, unspecified
0.000 0.865 0.135
E20-E35 Disorders of other endocrine glands
0.000 0.866 0.133
E88 Other metabolic disorders
0.000 0.873 0.127
E55.9 Vitamin D deficiency, unspecified
0.000 0.874 0.126
E61.9 Deficiency of nutrient element, unspecified
0.000 0.874 0.126
E61.8 Deficiency of other specified nutrient elements
0.000 0.874 0.126
E61.7 Deficiency of multiple nutrient elements
0.000 0.874 0.126
E61.6 Vanadium deficiency
0.000 0.874 0.126
E61.5 Molybdenum deficiency
0.000 0.874 0.126
E61.4 Chromium deficiency
0.000 0.874 0.126
E61.3 Manganese deficiency
0.000 0.874 0.126
E61.0 Copper deficiency
0.000 0.874 0.126
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.875 0.124
E78.6 Lipoprotein deficiency
0.000 0.875 0.125
E74 Other disorders of carbohydrate metabolism
0.001 0.878 0.121
E24 Cushing's syndrome
0.000 0.879 0.121
E78.3 Hyperchylomicronaemia
0.000 0.883 0.117
E84 Cystic fibrosis
0.001 0.884 0.115
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.885 0.115
E53.9 Vitamin B deficiency, unspecified
0.000 0.885 0.115
E77 Disorders of glycoprotein metabolism
0.001 0.885 0.114
E76 Disorders of glycosaminoglycan metabolism
0.001 0.885 0.114
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.885 0.114
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.885 0.114
E85 Amyloidosis
0.001 0.886 0.113
E03.9 Hypothyroidism, unspecified
0.000 0.886 0.114
E73 Lactose intolerance
0.001 0.886 0.113
E53.1 Pyridoxine deficiency
0.000 0.887 0.113
E53.0 Riboflavin deficiency
0.000 0.887 0.113
E61.2 Magnesium deficiency
0.000 0.889 0.110
E88.9 Metabolic disorder, unspecified
0.000 0.890 0.110
E70 Disorders of aromatic amino-acid metabolism
0.001 0.891 0.108
E79 Disorders of purine and pyrimidine metabolism
0.001 0.893 0.106
E72 Other disorders of amino-acid metabolism
0.001 0.895 0.103
M45 Ankylosing spondylitis
0.104 0.896 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.896 0.104
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.897 0.103
I83.0 Varicose veins of lower extremities with ulcer
0.101 0.899 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.899 0.101
E88.2 Lipomatosis, not elsewhere classified
0.000 0.900 0.100
E20 Hypoparathyroidism
0.000 0.900 0.100
E75.5 Other lipid storage disorders
0.001 0.901 0.099
E78.4 Other hyperlipidaemia
0.000 0.901 0.099
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.903 0.097
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.903 0.097
E21.3 Hyperparathyroidism, unspecified
0.000 0.904 0.096
E28 Ovarian dysfunction
0.000 0.904 0.096
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.904 0.096
E32 Diseases of thymus
0.000 0.904 0.096
E30 Disorders of puberty, not elsewhere classified
0.000 0.904 0.096
E61.1 Iron deficiency
0.000 0.904 0.096
E25 Adrenogenital disorders
0.000 0.905 0.095
E31 Polyglandular dysfunction
0.000 0.906 0.094
E85.4 Organ-limited amyloidosis
0.001 0.906 0.093
E11.3 With ophthalmic complications
0.000 0.907 0.093
E24.2 Drug-induced Cushing's syndrome
0.000 0.908 0.091
E75.2 Other sphingolipidosis
0.001 0.909 0.091
E75.6 Lipid storage disorder, unspecified
0.001 0.910 0.089
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.910 0.089
E75.3 Sphingolipidosis, unspecified
0.001 0.910 0.089
E75.1 Other gangliosidosis
0.001 0.910 0.089
E75.0 GM2 gangliosidosis
0.001 0.910 0.089
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.912 0.087
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.912 0.087
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.912 0.087
E74.2 Disorders of galactose metabolism
0.001 0.912 0.087
E74.1 Disorders of fructose metabolism
0.001 0.912 0.087
E24.8 Other Cushing's syndrome
0.000 0.913 0.087
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.913 0.087
E24.3 Ectopic ACTH syndrome
0.000 0.913 0.087
E24.1 Nelson's syndrome
0.000 0.913 0.087
E85.3 Secondary systemic amyloidosis
0.001 0.914 0.085
E88.8 Other specified metabolic disorders
0.001 0.914 0.085
E74.0 Glycogen storage disease
0.001 0.915 0.085
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.915 0.084
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.084 0.915 0.000
E84.8 Cystic fibrosis with other manifestations
0.001 0.916 0.083
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.916 0.083
E85.8 Other amyloidosis
0.001 0.917 0.082
E71.3 Disorders of fatty-acid metabolism
0.001 0.917 0.082
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.917 0.082
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.917 0.082
E71.0 Maple-syrup-urine disease
0.001 0.917 0.082
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.917 0.082
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.917 0.082
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.917 0.082
E76.2 Other mucopolysaccharidoses
0.001 0.917 0.082
E76.1 Mucopolysaccharidosis, type II
0.001 0.917 0.082
E76.0 Mucopolysaccharidosis, type I
0.001 0.917 0.082
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.917 0.082
E77.8 Other disorders of glycoprotein metabolism
0.001 0.917 0.082
E77.1 Defects in glycoprotein degradation
0.001 0.917 0.082
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.917 0.082
M45.X2 Ankylosing spondylitis (Cervical region)
0.083 0.917 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.917 0.083
E84.9 Cystic fibrosis, unspecified
0.001 0.917 0.082
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.918 0.081
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.918 0.081
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.918 0.081
E73.8 Other lactose intolerance
0.001 0.918 0.081
E73.1 Secondary lactase deficiency
0.001 0.918 0.081
E73.0 Congenital lactase deficiency
0.001 0.918 0.081
M45.X6 Ankylosing spondylitis (Lumbar region)
0.081 0.919 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.920 0.080
E29 Testicular dysfunction
0.000 0.921 0.079
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.921 0.078
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.921 0.078
E70.2 Disorders of tyrosine metabolism
0.001 0.921 0.078
E70.1 Other hyperphenylalaninaemias
0.001 0.921 0.078
E70.0 Classical phenylketonuria
0.001 0.921 0.078
E11.4 With neurological complications
0.000 0.922 0.078
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.923 0.076
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.923 0.076
E79.1 Lesch-Nyhan syndrome
0.001 0.923 0.076
E83.4 Disorders of magnesium metabolism
0.062 0.923 0.015
E20.9 Hypoparathyroidism, unspecified
0.000 0.924 0.076
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.925 0.074
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.925 0.074
E72.5 Disorders of glycine metabolism
0.001 0.925 0.074
E72.4 Disorders of ornithine metabolism
0.001 0.925 0.074
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.925 0.074
E72.2 Disorders of urea cycle metabolism
0.001 0.925 0.074
E88.3 Tumour lysis syndrome
0.001 0.925 0.075
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.075 0.925 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.075 0.925 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.075 0.925 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.075 0.925 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.075 0.925 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.075 0.925 0.000
E34 Other endocrine disorders
0.000 0.926 0.074
E21.2 Other hyperparathyroidism
0.000 0.926 0.074
E21.4 Other specified disorders of parathyroid gland
0.000 0.926 0.074
E72.0 Disorders of amino-acid transport
0.001 0.927 0.072
E70.3 Albinism
0.001 0.927 0.072
E28.2 Polycystic ovarian syndrome
0.000 0.927 0.073
E20.8 Other hypoparathyroidism
0.000 0.928 0.072
E20.1 Pseudohypoparathyroidism
0.000 0.928 0.072
E20.0 Idiopathic hypoparathyroidism
0.000 0.928 0.072
E78.8 Other disorders of lipoprotein metabolism
0.000 0.930 0.070
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.930 0.068
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.931 0.069
E28.9 Ovarian dysfunction, unspecified
0.000 0.931 0.069
E28.8 Other ovarian dysfunction
0.000 0.931 0.069
E28.1 Androgen excess
0.000 0.931 0.069
E28.0 Oestrogen excess
0.000 0.931 0.069
E30.9 Disorder of puberty, unspecified
0.000 0.931 0.069
E30.8 Other disorders of puberty
0.000 0.931 0.069
E30.1 Precocious puberty
0.000 0.931 0.069
E30.0 Delayed puberty
0.000 0.931 0.069
E32.9 Disease of thymus, unspecified
0.000 0.931 0.069
E32.8 Other diseases of thymus
0.000 0.931 0.069
E32.1 Abscess of thymus
0.000 0.931 0.069
E32.0 Persistent hyperplasia of thymus
0.000 0.931 0.069
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.931 0.069
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.931 0.069
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.931 0.069
E25.9 Adrenogenital disorder, unspecified
0.000 0.931 0.068
E25.8 Other adrenogenital disorders
0.000 0.931 0.068
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.932 0.068
E31.9 Polyglandular dysfunction, unspecified
0.000 0.932 0.068
E31.8 Other polyglandular dysfunction
0.000 0.932 0.068
E31.1 Polyglandular hyperfunction
0.000 0.932 0.068
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.932 0.066
C15-C26 Malignant neoplasms of digestive organs
0.000 0.933 0.067
C20 Malignant neoplasm of rectum
0.000 0.933 0.067
C15 Malignant neoplasm of oesophagus
0.000 0.934 0.066
E31.0 Autoimmune polyglandular failure
0.000 0.934 0.066
E28.3 Primary ovarian failure
0.000 0.935 0.065
E26 Hyperaldosteronism
0.000 0.937 0.062
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.062 0.938 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.940 0.059
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.940 0.060
C15.5 Lower third of oesophagus
0.000 0.941 0.059
C15.4 Middle third of oesophagus
0.000 0.942 0.058
E29.8 Other testicular dysfunction
0.000 0.943 0.057
E29.0 Testicular hyperfunction
0.000 0.943 0.057
I83.1 Varicose veins of lower extremities with inflammation
0.056 0.944 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.945 0.055
E78.0 Pure hypercholesterolaemia
0.000 0.945 0.055
E85.9 Amyloidosis, unspecified
0.001 0.945 0.054
E34.3 Short stature, not elsewhere classified
0.000 0.946 0.054
C25 Malignant neoplasm of pancreas
0.000 0.946 0.054
E34.5 Androgen resistance syndrome
0.000 0.946 0.053
E34.4 Constitutional tall stature
0.000 0.946 0.053
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.946 0.053
E34.1 Other hypersecretion of intestinal hormones
0.000 0.946 0.053
C15.9 Oesophagus, unspecified
0.000 0.947 0.053
E23 Hypofunction and other disorders of pituitary gland
0.000 0.947 0.052
C15.0 Cervical part of oesophagus
0.000 0.949 0.051
E22 Hyperfunction of pituitary gland
0.000 0.949 0.051
C15.3 Upper third of oesophagus
0.000 0.950 0.050
E34.8 Other specified endocrine disorders
0.000 0.950 0.050
C17 Malignant neoplasm of small intestine
0.000 0.951 0.049
E34.9 Endocrine disorder, unspecified
0.000 0.951 0.048
C15.1 Thoracic part of oesophagus
0.000 0.952 0.048
C15.8 Overlapping lesion of oesophagus
0.000 0.952 0.048
C15.2 Abdominal part of oesophagus
0.000 0.952 0.048
E21.0 Primary hyperparathyroidism
0.000 0.952 0.048
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.953 0.047
C17.0 Duodenum
0.000 0.953 0.047
E80.2 Other porphyria
0.001 0.954 0.045
E23.7 Disorder of pituitary gland, unspecified
0.000 0.954 0.045
E26.8 Other hyperaldosteronism
0.000 0.955 0.045
E26.1 Secondary hyperaldosteronism
0.000 0.955 0.045
C25.3 Pancreatic duct
0.000 0.955 0.045
E04 Other non-toxic goitre
0.002 0.955 0.043
C25.2 Tail of pancreas
0.000 0.956 0.044
E34.0 Carcinoid syndrome
0.000 0.956 0.044
C25.1 Body of pancreas
0.000 0.956 0.044
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.956 0.043
E80.5 Crigler-Najjar syndrome
0.001 0.956 0.043
E80.3 Defects of catalase and peroxydase
0.001 0.956 0.043
E80.0 Hereditary erythropoietic porphyria
0.001 0.956 0.043
C21 Malignant neoplasm of anus and anal canal
0.000 0.956 0.044
E29.1 Testicular hypofunction
0.000 0.958 0.042
C25.8 Overlapping lesion of pancreas
0.000 0.958 0.042
C25.4 Endocrine pancreas
0.000 0.958 0.042
C24.0 Extrahepatic bile duct
0.000 0.958 0.041
E26.9 Hyperaldosteronism, unspecified
0.001 0.960 0.039
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.962 0.038
E23.1 Drug-induced hypopituitarism
0.000 0.962 0.038
E80.6 Other disorders of bilirubin metabolism
0.001 0.963 0.036
E22.8 Other hyperfunction of pituitary gland
0.000 0.963 0.037
E80.1 Porphyria cutanea tarda
0.001 0.964 0.035
C17.8 Overlapping lesion of small intestine
0.000 0.965 0.035
C17.3 Meckel's diverticulum
0.000 0.965 0.035
C25.7 Other parts of pancreas
0.000 0.965 0.035
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.965 0.035
E22.1 Hyperprolactinaemia
0.000 0.965 0.035
C25.9 Pancreas, unspecified
0.000 0.965 0.035
R31 Unspecified haematuria
0.035 0.965 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.965 0.034
C24.8 Overlapping lesion of biliary tract
0.000 0.966 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
E04.8 Other specified non-toxic goitre
0.001 0.968 0.031
C24.9 Biliary tract, unspecified
0.000 0.968 0.032
C21.2 Cloacogenic zone
0.000 0.968 0.031
C17.1 Jejunum
0.000 0.968 0.031
E83.5 Disorders of calcium metabolism
0.006 0.969 0.025
I73.9 Peripheral vascular disease, unspecified
0.000 0.970 0.030
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.970 0.030
E66 Obesity
0.000 0.970 0.030
C23 Malignant neoplasm of gallbladder
0.000 0.971 0.029
I73 Other peripheral vascular diseases
0.000 0.971 0.029
I77 Other disorders of arteries and arterioles
0.000 0.971 0.029
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.972 0.027
I77.6 Arteritis, unspecified
0.000 0.972 0.028
C21.0 Anus, unspecified
0.000 0.973 0.027
E23.6 Other disorders of pituitary gland
0.000 0.973 0.027
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.973 0.027
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.973 0.027
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.973 0.027
C21.1 Anal canal
0.000 0.973 0.026
E23.2 Diabetes insipidus
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.025
E22.0 Acromegaly and pituitary gigantism
0.000 0.975 0.025
I77.8 Other specified disorders of arteries and arterioles
0.000 0.975 0.025
I73.0 Raynaud's syndrome
0.000 0.976 0.024
I72 Other aneurysm
0.000 0.976 0.024
E26.0 Primary hyperaldosteronism
0.001 0.976 0.023
I74 Arterial embolism and thrombosis
0.000 0.976 0.024
C17.9 Small intestine, unspecified
0.000 0.977 0.023
C17.2 Ileum
0.000 0.977 0.023
E11.9 Without complications
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.002 0.977 0.021
M45-M49 Spondylopathies
0.022 0.978 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.978 0.022
I73.8 Other specified peripheral vascular diseases
0.000 0.978 0.022
I77.3 Arterial fibromuscular dysplasia
0.000 0.978 0.022
C26.8 Overlapping lesion of digestive system
0.000 0.978 0.021
C26.1 Spleen
0.000 0.978 0.021
E66.1 Drug-induced obesity
0.000 0.978 0.021
I74.5 Embolism and thrombosis of iliac artery
0.000 0.978 0.022
I72.4 Aneurysm of artery of lower extremity
0.000 0.979 0.021
I70 Atherosclerosis
0.000 0.979 0.021
I77.2 Rupture of artery
0.000 0.979 0.021
I77.5 Necrosis of artery
0.000 0.979 0.021
I77.4 Coeliac artery compression syndrome
0.000 0.979 0.021
I77.1 Stricture of artery
0.000 0.979 0.021
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.979 0.020
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.980 0.020
I72.3 Aneurysm of iliac artery
0.000 0.980 0.020
C22.7 Other specified carcinomas of liver
0.000 0.980 0.020
C22.4 Other sarcomas of liver
0.000 0.980 0.020
C22.3 Angiosarcoma of liver
0.000 0.980 0.020
C22.2 Hepatoblastoma
0.000 0.980 0.020
C22.9 Liver, unspecified
0.000 0.980 0.020
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.981 0.019
I72.0 Aneurysm of carotid artery
0.000 0.981 0.019
I72.1 Aneurysm of artery of upper extremity
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.018
C24.1 Ampulla of Vater
0.001 0.981 0.018
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.982 0.018
E80.4 Gilbert's syndrome
0.001 0.982 0.017
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.982 0.018
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.982 0.018
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.982 0.018
E66.0 Obesity due to excess calories
0.000 0.982 0.017
C22.1 Intrahepatic bile duct carcinoma
0.000 0.983 0.017
M49 Spondylopathies in diseases classified elsewhere
0.017 0.983 0.000
I72.9 Aneurysm of unspecified site
0.000 0.983 0.017
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.983 0.017
E27 Other disorders of adrenal gland
0.000 0.983 0.017
I72.2 Aneurysm of renal artery
0.000 0.984 0.016
I70.8 Atherosclerosis of other arteries
0.000 0.984 0.016
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.984 0.016
C25.0 Head of pancreas
0.000 0.984 0.016
M46 Other inflammatory spondylopathies
0.016 0.984 0.000
I70.1 Atherosclerosis of renal artery
0.000 0.984 0.016

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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