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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs209176
log Bayes Factor = 51.4284
Chromosome 6   position 28,804,186  (GRCh37) Explore rs209176 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.005 0.995
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.008 0.992
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.008 0.992
E00-E07 Disorders of thyroid gland
0.000 0.011 0.989
E10.2 With renal complications
0.000 0.049 0.951
E10.1 With ketoacidosis
0.000 0.064 0.936
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.069 0.931
E10.4 With neurological complications
0.000 0.081 0.919
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.829 0.171 0.000
E13 Other specified diabetes mellitus
0.000 0.172 0.827
E05.8 Other thyrotoxicosis
0.000 0.192 0.808
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.215 0.785
E16.1 Other hypoglycaemia
0.000 0.228 0.772
E10.7 With multiple complications
0.000 0.252 0.748
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.289 0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.709
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.709
E13.9 Without complications
0.000 0.293 0.707
E14 Unspecified diabetes mellitus
0.000 0.294 0.706
E40-E46 Malnutrition
0.000 0.320 0.680
E10.6 With other specified complications
0.000 0.335 0.664
E10.5 With peripheral circulatory complications
0.000 0.361 0.638
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.366 0.633
E07 Other disorders of thyroid
0.000 0.374 0.626
E14.3 With ophthalmic complications
0.000 0.387 0.613
E13.3 With ophthalmic complications
0.000 0.404 0.596
E13.8 With unspecified complications
0.000 0.407 0.593
E13.7 With multiple complications
0.000 0.407 0.593
E13.6 With other specified complications
0.000 0.407 0.593
E13.5 With peripheral circulatory complications
0.000 0.407 0.593
E13.4 With neurological complications
0.000 0.407 0.593
E13.2 With renal complications
0.000 0.407 0.593
E13.1 With ketoacidosis
0.000 0.407 0.593
E13.0 With coma
0.000 0.407 0.593
E06 Thyroiditis
0.000 0.415 0.585
E14.1 With ketoacidosis
0.000 0.430 0.570
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.431 0.568
E14.4 With neurological complications
0.000 0.456 0.544
E10.8 With unspecified complications
0.000 0.467 0.532
E14.6 With other specified complications
0.000 0.483 0.517
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E14.8 With unspecified complications
0.000 0.490 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.491 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.491 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.491 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.491 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.491 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.491 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.491 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.491 0.508
E14.7 With multiple complications
0.000 0.494 0.506
E07.8 Other specified disorders of thyroid
0.000 0.508 0.492
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.513 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.513 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.513 0.487
E42 Marasmic kwashiorkor
0.000 0.513 0.487
E41 Nutritional marasmus
0.000 0.513 0.487
E40 Kwashiorkor
0.000 0.513 0.487
E14.2 Withrenal complications
0.000 0.519 0.481
E14.5 With peripheral circulatory complications
0.000 0.524 0.476
E14.0 With coma
0.000 0.527 0.473
E06.9 Thyroiditis, unspecified
0.000 0.531 0.469
K90 Intestinal malabsorption
0.000 0.534 0.465
E46 Unspecified protein-energy malnutrition
0.000 0.544 0.455
E07.1 Dyshormogenetic goitre
0.000 0.551 0.449
E07.0 Hypersecretion of calcitonin
0.000 0.551 0.449
E06.1 Subacute thyroiditis
0.000 0.561 0.439
E06.4 Drug-induced thyroiditis
0.000 0.580 0.419
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.580 0.419
E06.0 Acute thyroiditis
0.000 0.580 0.419
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.588 0.412
E06.5 Other chronic thyroiditis
0.000 0.599 0.401
E03 Other hypothyroidism
0.000 0.606 0.394
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.622 0.377
E44.1 Mild protein-energy malnutrition
0.000 0.650 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.650 0.349
K90.3 Pancreatic steatorrhoea
0.000 0.666 0.334
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.666 0.334
K90.1 Tropical sprue
0.000 0.666 0.334
E50-E64 Other nutritional deficiencies
0.000 0.668 0.332
E65-E68 Obesity and other hyperalimentation
0.000 0.668 0.331
K90.8 Other intestinal malabsorption
0.000 0.695 0.305
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.705 0.295
E03.1 Congenital hypothyroidism without goitre
0.000 0.716 0.284
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.717 0.283
E03.5 Myxoedema coma
0.000 0.717 0.283
E03.4 Atrophy of thyroid (acquired)
0.000 0.717 0.283
E03.3 Postinfectious hypothyroidism
0.000 0.717 0.283
E07.9 Disorder of thyroid, unspecified
0.000 0.717 0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.730 0.270
E11 Non-insulin-dependent diabetes mellitus
0.000 0.732 0.268
E11.6 With other specified complications
0.000 0.757 0.243
E54 Ascorbic acid deficiency
0.000 0.759 0.241
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.762 0.238
E63 Other nutritional deficiencies
0.000 0.762 0.238
E50 Vitamin A deficiency
0.000 0.762 0.238
E60 Dietary zinc deficiency
0.000 0.762 0.238
E59 Dietary selenium deficiency
0.000 0.762 0.238
E52 Niacin deficiency [pellagra]
0.000 0.762 0.238
E67 Other hyperalimentation
0.000 0.762 0.238
E68 Sequelae of hyperalimentation
0.000 0.762 0.238
E03.8 Other specified hypothyroidism
0.000 0.763 0.237
E51 Thiamine deficiency
0.000 0.764 0.236
K90.9 Intestinal malabsorption, unspecified
0.000 0.768 0.232
E56 Other vitamin deficiencies
0.000 0.769 0.231
E11.1 With ketoacidosis
0.000 0.771 0.229
E11.0 With coma
0.000 0.779 0.221
E55 Vitamin D deficiency
0.000 0.785 0.215
E58 Dietary calcium deficiency
0.000 0.794 0.206
E20-E35 Disorders of other endocrine glands
0.000 0.798 0.202
E11.2 With renal complications
0.000 0.804 0.196
E11.7 With multiple complications
0.000 0.808 0.192
C15-C26 Malignant neoplasms of digestive organs
0.000 0.808 0.192
C20 Malignant neoplasm of rectum
0.000 0.811 0.189
C15 Malignant neoplasm of oesophagus
0.000 0.815 0.185
E65 Localised adiposity
0.000 0.815 0.185
E61 Deficiency of other nutrient elements
0.000 0.816 0.184
E24 Cushing's syndrome
0.000 0.817 0.183
I83 Varicose veins of lower extremities
0.176 0.824 0.000
C25 Malignant neoplasm of pancreas
0.000 0.826 0.174
E50.9 Vitamin A deficiency, unspecified
0.000 0.829 0.171
E50.8 Other manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.829 0.171
E50.5 Vitamin A deficiency with night blindness
0.000 0.829 0.171
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.829 0.171
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.829 0.171
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.829 0.171
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.829 0.171
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.829 0.171
E63.9 Nutritional deficiency, unspecified
0.000 0.829 0.171
E63.8 Other specified nutritional deficiencies
0.000 0.829 0.171
E63.1 Imbalance of constituents of food intake
0.000 0.829 0.171
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.829 0.171
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.829 0.171
E64.8 Sequelae of other nutritional deficiencies
0.000 0.829 0.171
E64.3 Sequelae of rickets
0.000 0.829 0.171
E64.2 Sequelae of vitamin C deficiency
0.000 0.829 0.171
E64.1 Sequelae of vitamin A deficiency
0.000 0.829 0.171
E64.0 Sequelae of protein-energy malnutrition
0.000 0.829 0.171
E67.8 Other specified hyperalimentation
0.000 0.829 0.171
E67.3 Hypervitaminosis D
0.000 0.829 0.171
E67.2 Megavitamin-B6 syndrome
0.000 0.829 0.171
E67.1 Hypercarotenaemia
0.000 0.829 0.171
E67.0 Hypervitaminosis A
0.000 0.829 0.171
E51.9 Thiamine deficiency, unspecified
0.000 0.830 0.169
E51.8 Other manifestations of thiamine deficiency
0.000 0.830 0.169
E51.1 Beriberi
0.000 0.830 0.169
E51.2 Wernicke's encephalopathy
0.000 0.832 0.167
E56.9 Vitamin deficiency, unspecified
0.000 0.834 0.166
E56.8 Deficiency of other vitamins
0.000 0.834 0.166
E56.0 Deficiency of vitamin E
0.000 0.834 0.166
C15.4 Middle third of oesophagus
0.000 0.835 0.165
E53 Deficiency of other B group vitamins
0.000 0.837 0.163
E06.3 Autoimmune thyroiditis
0.000 0.839 0.161
E56.1 Deficiency of vitamin K
0.000 0.841 0.158
E28 Ovarian dysfunction
0.000 0.842 0.158
E11.8 With unspecified complications
0.000 0.843 0.157
C15.5 Lower third of oesophagus
0.000 0.844 0.156
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.844 0.156
E83 Disorders of mineral metabolism
0.133 0.844 0.023
E55.0 Rickets, active
0.000 0.846 0.154
E24.9 Cushing's syndrome, unspecified
0.000 0.848 0.152
E24.0 Pituitary-dependent Cushing's disease
0.000 0.849 0.151
C15.9 Oesophagus, unspecified
0.000 0.850 0.150
E20 Hypoparathyroidism
0.000 0.850 0.150
M45.X9 Ankylosing spondylitis (Site unspecified)
0.148 0.852 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.855 0.145
E32 Diseases of thymus
0.000 0.855 0.145
E30 Disorders of puberty, not elsewhere classified
0.000 0.855 0.145
C25.3 Pancreatic duct
0.000 0.856 0.144
E21.3 Hyperparathyroidism, unspecified
0.000 0.857 0.143
C15.0 Cervical part of oesophagus
0.000 0.857 0.143
E24.2 Drug-induced Cushing's syndrome
0.000 0.857 0.143
C25.2 Tail of pancreas
0.000 0.858 0.142
E31 Polyglandular dysfunction
0.000 0.858 0.142
C25.1 Body of pancreas
0.000 0.859 0.141
E25 Adrenogenital disorders
0.000 0.860 0.140
C25.8 Overlapping lesion of pancreas
0.000 0.860 0.140
E29 Testicular dysfunction
0.000 0.860 0.139
C25.4 Endocrine pancreas
0.000 0.861 0.139
C15.3 Upper third of oesophagus
0.000 0.861 0.139
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.864 0.136
C17 Malignant neoplasm of small intestine
0.000 0.864 0.136
C15.1 Thoracic part of oesophagus
0.000 0.865 0.134
C15.8 Overlapping lesion of oesophagus
0.000 0.867 0.133
C15.2 Abdominal part of oesophagus
0.000 0.867 0.133
E24.8 Other Cushing's syndrome
0.000 0.868 0.132
I83.0 Varicose veins of lower extremities with ulcer
0.132 0.868 0.000
E14.9 Without complications
0.000 0.868 0.132
C25.9 Pancreas, unspecified
0.000 0.868 0.132
E61.9 Deficiency of nutrient element, unspecified
0.000 0.868 0.132
E61.8 Deficiency of other specified nutrient elements
0.000 0.868 0.132
E61.7 Deficiency of multiple nutrient elements
0.000 0.868 0.132
E61.6 Vanadium deficiency
0.000 0.868 0.132
E61.5 Molybdenum deficiency
0.000 0.868 0.132
E61.4 Chromium deficiency
0.000 0.868 0.132
E61.3 Manganese deficiency
0.000 0.868 0.132
E61.0 Copper deficiency
0.000 0.868 0.132
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.869 0.131
E24.3 Ectopic ACTH syndrome
0.000 0.869 0.131
E24.1 Nelson's syndrome
0.000 0.869 0.131
E55.9 Vitamin D deficiency, unspecified
0.000 0.869 0.131
E28.2 Polycystic ovarian syndrome
0.000 0.870 0.130
C17.0 Duodenum
0.000 0.872 0.128
E11.5 With peripheral circulatory complications
0.000 0.879 0.121
E53.9 Vitamin B deficiency, unspecified
0.000 0.880 0.120
C24.0 Extrahepatic bile duct
0.000 0.881 0.119
C25.7 Other parts of pancreas
0.000 0.881 0.119
E70-E90 Metabolic disorders
0.001 0.881 0.118
C21 Malignant neoplasm of anus and anal canal
0.000 0.883 0.117
E53.1 Pyridoxine deficiency
0.000 0.883 0.117
E53.0 Riboflavin deficiency
0.000 0.883 0.117
E34 Other endocrine disorders
0.000 0.884 0.116
E61.2 Magnesium deficiency
0.000 0.884 0.116
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.886 0.114
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.886 0.114
E28.9 Ovarian dysfunction, unspecified
0.000 0.887 0.113
E28.8 Other ovarian dysfunction
0.000 0.887 0.113
E28.1 Androgen excess
0.000 0.887 0.113
E28.0 Oestrogen excess
0.000 0.887 0.113
E83.3 Disorders of phosphorus metabolism
0.106 0.887 0.007
E20.9 Hypoparathyroidism, unspecified
0.000 0.888 0.112
E21.2 Other hyperparathyroidism
0.000 0.888 0.112
E21.4 Other specified disorders of parathyroid gland
0.000 0.888 0.112
E83.8 Other disorders of mineral metabolism
0.095 0.888 0.017
E83.2 Disorders of zinc metabolism
0.095 0.888 0.017
E83.0 Disorders of copper metabolism
0.095 0.888 0.017
E83.9 Disorder of mineral metabolism, unspecified
0.095 0.889 0.016
E78.2 Mixed hyperlipidaemia
0.000 0.889 0.111
E20.8 Other hypoparathyroidism
0.000 0.892 0.108
E20.1 Pseudohypoparathyroidism
0.000 0.892 0.108
E20.0 Idiopathic hypoparathyroidism
0.000 0.892 0.108
E28.3 Primary ovarian failure
0.000 0.894 0.106
E30.9 Disorder of puberty, unspecified
0.000 0.896 0.104
E30.8 Other disorders of puberty
0.000 0.896 0.104
E30.1 Precocious puberty
0.000 0.896 0.104
E30.0 Delayed puberty
0.000 0.896 0.104
E32.9 Disease of thymus, unspecified
0.000 0.896 0.104
E32.8 Other diseases of thymus
0.000 0.896 0.104
E32.1 Abscess of thymus
0.000 0.896 0.104
E32.0 Persistent hyperplasia of thymus
0.000 0.896 0.104
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.896 0.104
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.896 0.104
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.896 0.104
E61.1 Iron deficiency
0.000 0.897 0.103
E31.9 Polyglandular dysfunction, unspecified
0.000 0.898 0.102
E31.8 Other polyglandular dysfunction
0.000 0.898 0.102
E31.1 Polyglandular hyperfunction
0.000 0.898 0.102
E29.9 Testicular dysfunction, unspecified
0.000 0.898 0.102
E25.9 Adrenogenital disorder, unspecified
0.000 0.899 0.100
E25.8 Other adrenogenital disorders
0.000 0.899 0.100
E29.8 Other testicular dysfunction
0.000 0.900 0.100
E29.0 Testicular hyperfunction
0.000 0.900 0.100
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.100 0.900 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.901 0.099
C24.8 Overlapping lesion of biliary tract
0.000 0.902 0.098
C17.8 Overlapping lesion of small intestine
0.000 0.902 0.097
C17.3 Meckel's diverticulum
0.000 0.902 0.097
E78.1 Pure hyperglyceridaemia
0.000 0.903 0.097
C24.9 Biliary tract, unspecified
0.000 0.904 0.096
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.905 0.095
E78.5 Hyperlipidaemia, unspecified
0.000 0.905 0.095
C23 Malignant neoplasm of gallbladder
0.000 0.906 0.093
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.907 0.092
E29.1 Testicular hypofunction
0.000 0.907 0.093
E26 Hyperaldosteronism
0.001 0.907 0.092
E74 Other disorders of carbohydrate metabolism
0.001 0.908 0.091
E78.6 Lipoprotein deficiency
0.000 0.908 0.091
E88 Other metabolic disorders
0.000 0.909 0.091
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.909 0.091
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.909 0.091
E03.9 Hypothyroidism, unspecified
0.000 0.910 0.090
C17.1 Jejunum
0.000 0.913 0.086
E73 Lactose intolerance
0.001 0.914 0.085
E84 Cystic fibrosis
0.001 0.914 0.085
E78.3 Hyperchylomicronaemia
0.000 0.914 0.086
E77 Disorders of glycoprotein metabolism
0.001 0.914 0.085
E76 Disorders of glycosaminoglycan metabolism
0.001 0.914 0.085
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.914 0.085
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.914 0.085
E34.3 Short stature, not elsewhere classified
0.000 0.915 0.084
C21.2 Cloacogenic zone
0.000 0.916 0.084
E85 Amyloidosis
0.001 0.916 0.083
E72 Other disorders of amino-acid metabolism
0.001 0.916 0.083
E34.5 Androgen resistance syndrome
0.000 0.916 0.083
E34.4 Constitutional tall stature
0.000 0.916 0.083
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.916 0.083
E34.1 Other hypersecretion of intestinal hormones
0.000 0.916 0.083
E23 Hypofunction and other disorders of pituitary gland
0.000 0.916 0.083
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.917 0.083
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.918 0.082
E11.3 With ophthalmic complications
0.000 0.918 0.082
E21.0 Primary hyperparathyroidism
0.000 0.919 0.081
E70 Disorders of aromatic amino-acid metabolism
0.001 0.919 0.080
E34.8 Other specified endocrine disorders
0.000 0.919 0.081
E22 Hyperfunction of pituitary gland
0.000 0.919 0.080
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.920 0.080
E79 Disorders of purine and pyrimidine metabolism
0.001 0.920 0.079
E88.9 Metabolic disorder, unspecified
0.000 0.921 0.079
E34.9 Endocrine disorder, unspecified
0.000 0.921 0.079
M45 Ankylosing spondylitis
0.078 0.922 0.000
E78.4 Other hyperlipidaemia
0.000 0.924 0.075
E75.5 Other lipid storage disorders
0.001 0.926 0.073
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.927 0.072
E23.7 Disorder of pituitary gland, unspecified
0.000 0.928 0.072
E88.2 Lipomatosis, not elsewhere classified
0.000 0.928 0.071
C21.0 Anus, unspecified
0.000 0.929 0.071
C21.1 Anal canal
0.000 0.930 0.070
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.930 0.069
E85.4 Organ-limited amyloidosis
0.000 0.931 0.068
E75.2 Other sphingolipidosis
0.001 0.932 0.067
C25.0 Head of pancreas
0.000 0.933 0.067
E75.6 Lipid storage disorder, unspecified
0.001 0.933 0.066
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.933 0.066
E75.3 Sphingolipidosis, unspecified
0.001 0.933 0.066
E75.1 Other gangliosidosis
0.001 0.933 0.066
E75.0 GM2 gangliosidosis
0.001 0.933 0.066
E26.8 Other hyperaldosteronism
0.001 0.933 0.066
E26.1 Secondary hyperaldosteronism
0.001 0.933 0.066
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.934 0.066
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.934 0.066
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.934 0.066
E74.2 Disorders of galactose metabolism
0.001 0.934 0.066
E74.1 Disorders of fructose metabolism
0.001 0.934 0.066
E74.0 Glycogen storage disease
0.001 0.934 0.066
E34.0 Carcinoid syndrome
0.000 0.935 0.065
C17.9 Small intestine, unspecified
0.000 0.937 0.063
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.937 0.062
E85.3 Secondary systemic amyloidosis
0.001 0.937 0.062
I83.1 Varicose veins of lower extremities with inflammation
0.063 0.937 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.937 0.062
M45.X2 Ankylosing spondylitis (Cervical region)
0.062 0.938 0.000
E73.8 Other lactose intolerance
0.001 0.938 0.061
E73.1 Secondary lactase deficiency
0.001 0.938 0.061
E73.0 Congenital lactase deficiency
0.001 0.938 0.061
E84.8 Cystic fibrosis with other manifestations
0.001 0.938 0.061
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.938 0.061
E71.3 Disorders of fatty-acid metabolism
0.001 0.938 0.061
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.938 0.061
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.938 0.061
E71.0 Maple-syrup-urine disease
0.001 0.938 0.061
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.938 0.061
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.938 0.061
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.938 0.061
E76.2 Other mucopolysaccharidoses
0.001 0.938 0.061
E76.1 Mucopolysaccharidosis, type II
0.001 0.938 0.061
E76.0 Mucopolysaccharidosis, type I
0.001 0.938 0.061
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.938 0.061
E77.8 Other disorders of glycoprotein metabolism
0.001 0.938 0.061
E77.1 Defects in glycoprotein degradation
0.001 0.938 0.061
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.938 0.061
E88.8 Other specified metabolic disorders
0.000 0.938 0.061
E84.9 Cystic fibrosis, unspecified
0.001 0.939 0.060
E85.8 Other amyloidosis
0.001 0.939 0.060
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.940 0.060
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.940 0.060
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.940 0.060
M45.X6 Ankylosing spondylitis (Lumbar region)
0.060 0.940 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.940 0.059
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.940 0.059
E72.5 Disorders of glycine metabolism
0.001 0.940 0.059
E72.4 Disorders of ornithine metabolism
0.001 0.940 0.059
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.940 0.059
E72.2 Disorders of urea cycle metabolism
0.001 0.940 0.059
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.940 0.059
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.940 0.060
E23.1 Drug-induced hypopituitarism
0.000 0.940 0.060
R31 Unspecified haematuria
0.060 0.940 0.000
C17.2 Ileum
0.000 0.940 0.059
C26.8 Overlapping lesion of digestive system
0.000 0.941 0.059
C26.1 Spleen
0.000 0.941 0.059
E83.4 Disorders of magnesium metabolism
0.049 0.941 0.009
E72.0 Disorders of amino-acid transport
0.001 0.941 0.058
E26.9 Hyperaldosteronism, unspecified
0.001 0.941 0.058
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.942 0.058
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.942 0.058
E70.2 Disorders of tyrosine metabolism
0.001 0.942 0.058
E70.1 Other hyperphenylalaninaemias
0.001 0.942 0.058
E70.0 Classical phenylketonuria
0.001 0.942 0.058
E22.8 Other hyperfunction of pituitary gland
0.000 0.942 0.058
C22.7 Other specified carcinomas of liver
0.000 0.942 0.057
C22.4 Other sarcomas of liver
0.000 0.942 0.057
C22.3 Angiosarcoma of liver
0.000 0.942 0.057
C22.2 Hepatoblastoma
0.000 0.942 0.057
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.943 0.056
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.943 0.056
E79.1 Lesch-Nyhan syndrome
0.001 0.943 0.056
E78.8 Other disorders of lipoprotein metabolism
0.000 0.943 0.057
E11.4 With neurological complications
0.000 0.943 0.057
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.056 0.944 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.056 0.944 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.056 0.944 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.056 0.944 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.056 0.944 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.056 0.944 0.000
C22.1 Intrahepatic bile duct carcinoma
0.000 0.944 0.056
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.945 0.055
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.946 0.054
E22.1 Hyperprolactinaemia
0.000 0.946 0.054
E88.3 Tumour lysis syndrome
0.001 0.946 0.053
E70.3 Albinism
0.001 0.946 0.053
E04 Other non-toxic goitre
0.002 0.946 0.052
C24.1 Ampulla of Vater
0.001 0.947 0.052
C22.9 Liver, unspecified
0.000 0.948 0.052
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.949 0.051
C18 Malignant neoplasm of colon
0.000 0.951 0.049
C18.1 Appendix
0.000 0.952 0.048
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.954 0.046
E23.2 Diabetes insipidus
0.000 0.955 0.045
E78.0 Pure hypercholesterolaemia
0.000 0.955 0.045
C18.9 Colon, unspecified
0.000 0.955 0.045
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.044 0.955 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.957 0.042
E23.6 Other disorders of pituitary gland
0.000 0.958 0.042
C26.9 Ill-defined sites within the digestive system
0.001 0.958 0.041
E85.9 Amyloidosis, unspecified
0.001 0.960 0.039
E04.8 Other specified non-toxic goitre
0.001 0.961 0.038
E22.0 Acromegaly and pituitary gigantism
0.000 0.962 0.038
C26.0 Intestinal tract, part unspecified
0.000 0.963 0.037
E53.8 Deficiency of other specified B group vitamins
0.000 0.964 0.036
C18.8 Overlapping lesion of colon
0.000 0.965 0.035
C16 Malignant neoplasm of stomach
0.000 0.966 0.034
E26.0 Primary hyperaldosteronism
0.001 0.967 0.032
E80.2 Other porphyria
0.001 0.967 0.032
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.969 0.031
E80.5 Crigler-Najjar syndrome
0.001 0.969 0.031
E80.3 Defects of catalase and peroxydase
0.001 0.969 0.031
E80.0 Hereditary erythropoietic porphyria
0.001 0.969 0.031
C18.4 Transverse colon
0.000 0.969 0.031
E04.0 Non-toxic diffuse goitre
0.001 0.970 0.029
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E27 Other disorders of adrenal gland
0.000 0.972 0.028
E66 Obesity
0.000 0.972 0.028
C18.6 Descending colon
0.000 0.972 0.027
C18.7 Sigmoid colon
0.000 0.973 0.027
E80.6 Other disorders of bilirubin metabolism
0.001 0.973 0.026
E80.1 Porphyria cutanea tarda
0.001 0.974 0.025
C16.2 Body of stomach
0.000 0.975 0.025
C18.3 Hepatic flexure
0.000 0.975 0.025
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.024 0.976 0.000
E23.0 Hypopituitarism
0.000 0.976 0.024
C16.6 Greater curvature of stomach, unspecified
0.000 0.977 0.022
C16.5 Lesser curvature of stomach, unspecified
0.000 0.977 0.022
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.022 0.978 0.000
C16.8 Overlapping lesion of stomach
0.000 0.978 0.021
M45-M49 Spondylopathies
0.021 0.979 0.000
C16.4 Pylorus
0.000 0.979 0.021
C16.0 Cardia
0.000 0.979 0.021
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
E83.5 Disorders of calcium metabolism
0.006 0.979 0.015
E27.5 Adrenomedullary hyperfunction
0.000 0.980 0.020
E27.0 Other adrenocortical overactivity
0.000 0.980 0.020
E66.1 Drug-induced obesity
0.000 0.980 0.020
I86 Varicose veins of other sites
0.020 0.980 0.000
C16.1 Fundus of stomach
0.000 0.980 0.020
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.020 0.980 0.000
I81 Portal vein thrombosis
0.019 0.981 0.000
Z72.0 Tobacco use
0.019 0.981 0.000
C22.0 Liver cell carcinoma
0.001 0.981 0.018
I89.0 Lymphoedema, not elsewhere classified
0.019 0.981 0.000
C16.3 Pyloric antrum
0.000 0.981 0.018
I86.8 Varicose veins of other specified sites
0.018 0.982 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.982 0.018
C16.9 Stomach, unspecified
0.000 0.982 0.018
E27.1 Primary adrenocortical insufficiency
0.000 0.982 0.018
I89.1 Lymphangitis
0.017 0.983 0.000
E27.2 Addisonian crisis
0.000 0.983 0.017
M49 Spondylopathies in diseases classified elsewhere
0.017 0.983 0.000
E11.9 Without complications
0.000 0.983 0.017
I82 Other venous embolism and thrombosis
0.017 0.983 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.984 0.016
I87 Other disorders of veins
0.016 0.984 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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