TreeWAS – Variant ID: rs2106595

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H53.8 Other visual disturbances	0.025	0.975	0.000
D86.9 Sarcoidosis, unspecified	0.022	0.978	0.000
D86 Sarcoidosis	0.015	0.985	0.000
R47.0 Dysphasia and aphasia	0.000	0.986	0.014
D86.0 Sarcoidosis of lung	0.013	0.987	0.000
K56.2 Volvulus	0.012	0.988	0.000
D86.8 Sarcoidosis of other and combined sites	0.011	0.989	0.000
D80-D89 Certain disorders involving the immune mechanism	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.010	0.990	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.010	0.990	0.000
D80 Immunodeficiency with predominantly antibody defects	0.010	0.990	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.010	0.990	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.009	0.991	0.000
D86.3 Sarcoidosis of skin	0.009	0.991	0.000
H53 Visual disturbances	0.009	0.991	0.000
C77.9 Lymph node, unspecified	0.008	0.992	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.008	0.992	0.000
D81 Combined immunodeficiencies	0.008	0.992	0.000
H53.0 Amblyopia ex anopsia	0.008	0.992	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.008	0.992	0.000
D82 Immunodeficiency associated with other major defects	0.008	0.992	0.000
Z33 Pregnant state, incidental	0.008	0.992	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.007	0.992	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.007	0.992	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.007	0.992	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.007	0.992	0.000
Z98.1 Arthrodesis status	0.007	0.993	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.007	0.993	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.007	0.993	0.000
D86.1 Sarcoidosis of lymph nodes	0.007	0.993	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.007	0.993	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.007	0.993	0.000
D89.3 Immune reconstitution syndrome	0.007	0.993	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.007	0.993	0.000
H53.2 Diplopia	0.007	0.993	0.000
H53.3 Other disorders of binocular vision	0.007	0.993	0.000
D89.1 Cryoglobulinaemia	0.007	0.993	0.000
D83 Common variable immunodeficiency	0.007	0.993	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.007	0.993	0.000
Z89.6 Acquired absence of leg above knee	0.007	0.993	0.000
D84 Other immunodeficiencies	0.006	0.993	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.007	0.993	0.000
H53.6 Night blindness	0.006	0.994	0.000
H53.5 Colour vision deficiencies	0.006	0.994	0.000
D68.0 Von Willebrand's disease	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.006	0.994	0.000
D81.8 Other combined immunodeficiencies	0.006	0.994	0.000
D81.7 Major histocompatibility complex class II deficiency	0.006	0.994	0.000
D81.6 Major histocompatibility complex class I deficiency	0.006	0.994	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.006	0.994	0.000
D81.4 Nezelof's syndrome	0.006	0.994	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.006	0.994	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.006	0.994	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.006	0.994	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.006	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.006	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.006	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.006	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.006	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.006	0.994	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.006	0.994	0.000
H01.0 Blepharitis	0.006	0.994	0.000
D82.1 Di George's syndrome	0.005	0.994	0.000
D84.8 Other specified immunodeficiencies	0.005	0.994	0.000
T40.2 Other opioids	0.000	0.995	0.005
K86 Other diseases of pancreas	0.005	0.995	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.995	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.995	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.995	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.995	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.995	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.005	0.995	0.000
H53.1 Subjective visual disturbances	0.005	0.995	0.000
H26.8 Other specified cataract	0.005	0.995	0.000
K86.9 Disease of pancreas, unspecified	0.005	0.995	0.000
K86.3 Pseudocyst of pancreas	0.005	0.995	0.000
K86.1 Other chronic pancreatitis	0.005	0.995	0.000
H53.9 Visual disturbance, unspecified	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.005	0.995	0.000
K86.2 Cyst of pancreas	0.005	0.995	0.000
T40.6 Other and unspecified narcotics	0.000	0.995	0.005
K86.8 Other specified diseases of pancreas	0.004	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.996	0.004
D84.1 Defects in the complement system	0.004	0.996	0.000
D83.9 Common variable immunodeficiency, unspecified	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.000	0.996	0.004
Z52.4 Kidney donor	0.000	0.996	0.004
D84.9 Immunodeficiency, unspecified	0.003	0.996	0.000
Z89 Acquired absence of limb	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.004	0.996	0.000
K11.5 Sialolithiasis	0.000	0.996	0.004
D68 Other coagulation defects	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.996	0.000
Z89.2 Acquired absence of upper limb above wrist	0.003	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
K56.5 Intestinal adhesions [bands] with obstruction	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
Z52.0 Blood donor	0.000	0.997	0.003
Z89.8 Acquired absence of upper and lower limbs [any level]	0.003	0.997	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.997	0.003
T40.5 Cocaine	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.003	0.997	0.000
Z52 Donors of organs and tissues	0.000	0.997	0.003
Z89.5 Acquired absence of leg at or below knee	0.003	0.997	0.000
I84.3 External thrombosed haemorrhoids	0.000	0.997	0.003
Y60.0 During surgical operation	0.000	0.997	0.003
M54.89 Other dorsalgia (Site unspecified)	0.003	0.997	0.000
F20 Schizophrenia	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.003	0.997	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.000	0.997	0.003
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.000	0.997	0.003
Y60.8 During other surgical and medical care	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
Z93.0 Tracheostomy status	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.002	0.998	0.000
Z52.8 Donor of other organs and tissues	0.000	0.998	0.002
F20.8 Other schizophrenia	0.002	0.998	0.000
Y60.4 During endoscopic examination	0.000	0.998	0.002
K25.7 Chronic without haemorrhage or perforation	0.000	0.998	0.002
Z52.9 Donor of unspecified organ or tissue	0.000	0.998	0.002
Z52.7 Heart donor	0.000	0.998	0.002
Z52.6 Liver donor	0.000	0.998	0.002
Z52.5 Cornea donor	0.000	0.998	0.002
Z52.1 Skin donor	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.002	0.998	0.000
Y95 Nosocomial condition	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.002	0.998	0.000
F20.4 Postschizophrenic depression	0.002	0.998	0.000
F20.3 Undifferentiated schizophrenia	0.002	0.998	0.000
F20.2 Catatonic schizophrenia	0.002	0.998	0.000
F20.1 Hebephrenic schizophrenia	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
K56.7 Ileus, unspecified	0.002	0.998	0.000
K56.0 Paralytic ileus	0.002	0.998	0.000
Y60.9 During unspecified surgical and medical care	0.000	0.998	0.002
Y60.7 During administration of enema	0.000	0.998	0.002
Y60.3 During injection or immunisation	0.000	0.998	0.002
Y60.2 During kidney dialysis or other perfusion	0.000	0.998	0.002
Y60.1 During infusion or transfusion	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
X50.6 Industrial and construction area	0.002	0.998	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.000	0.998	0.002
Z52.2 Bone donor	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
H01.8 Other specified inflammation of eyelid	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
D66 Hereditary factor VIII deficiency	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
M25.58 Pain in joint (Other)	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
K56.3 Gallstone ileus	0.002	0.998	0.000
K56.1 Intussusception	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
H54 Blindness and low vision	0.002	0.998	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.002	0.998	0.000
W02.9 Unspecified place	0.000	0.998	0.002
W44.0 Home	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.000	0.998	0.002
H54.2 Low vision, both eyes	0.002	0.998	0.000
W45.6 Industrial and construction area	0.002	0.998	0.000
D67 Hereditary factor IX deficiency	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.002	0.998	0.000
M19.98 Arthrosis, unspecified (Other)	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
H27.0 Aphakia	0.000	0.998	0.002
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.002	0.998	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.001	0.998	0.000
H01.9 Inflammation of eyelid, unspecified	0.001	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.998	0.002
M50.2 Other cervical disk displacement	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.002	0.998	0.000
H01.1 Non-infectious dermatoses of eyelid	0.001	0.998	0.000
H54.4 Blindness, one eye	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.001
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.001
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.001	0.999	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.999	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
M24.56 Contracture of joint (Lower leg)	0.000	0.999	0.001
S32.40 Fracture of acetabulum (closed)	0.000	0.999	0.001
F25.9 Schizoaffective disorder, unspecified	0.001	0.999	0.000
I77.1 Stricture of artery	0.000	0.999	0.001
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
G60.0 Hereditary motor and sensory neuropathy	0.001	0.999	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.999	0.001
D60-D64 Aplastic and other anaemias	0.001	0.999	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
M41.9 Scoliosis, unspecified	0.001	0.999	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.999	0.001
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.999	0.001
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.999	0.000
O32.8 Maternal care for other malpresentation of foetus	0.001	0.999	0.000
W45.4 Street and highway	0.001	0.999	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.001	0.999	0.000
J02.0 Streptococcal pharyngitis	0.001	0.999	0.000
N41.0 Acute prostatitis	0.001	0.999	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.999	0.001
M24.54 Contracture of joint (Hand)	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.999	0.001
Z13.6 Special screening examination for cardiovascular disorders	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.000	0.999	0.001
H54.0 Blindness, both eyes	0.001	0.999	0.000
K72.0 Acute and subacute hepatic failure	0.000	0.999	0.001
R68.8 Other specified general symptoms and signs	0.000	0.999	0.001
S32.5 Fracture of pubis	0.000	0.999	0.001
W45.5 Trade and service area	0.001	0.999	0.000
D12.4 Descending colon	0.001	0.999	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.001	0.999	0.000
R76.8 Other specified abnormal immunological findings in serum	0.001	0.999	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.001	0.999	0.000
W45 Foreign body or object entering through skin	0.001	0.999	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.001	0.999	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
H02.1 Ectropion of eyelid	0.000	0.999	0.001
S83.6 Sprain and strain of other and unspecified parts of knee	0.001	0.999	0.000
W45.8 Other specified place	0.001	0.999	0.000
D55-D59 Haemolytic anaemias	0.001	0.999	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
C05.1 Soft palate	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.001	0.999	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
R68.2 Dry mouth, unspecified	0.000	0.999	0.001
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.999	0.001
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.999	0.001
S32.4 Fracture of acetabulum	0.000	0.999	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.999	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
B01.9 Varicella without complications	0.000	0.999	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
F25.1 Schizoaffective disorder, depressive type	0.001	0.999	0.000
F25.0 Schizoaffective disorder, manic type	0.001	0.999	0.000
M23.5 Chronic instability of knee	0.000	0.999	0.001
T23.3 Burn of third degree of wrist and hand	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.001	0.999	0.000
C02.1 Border of tongue	0.001	0.999	0.000
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.999	0.001
M24.5 Contracture of joint	0.000	0.999	0.001
T45.5 Anticoagulants	0.001	0.999	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.999	0.001
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.999	0.001
Z35.6 Supervision of very young primigravida	0.000	0.999	0.001
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.999	0.001
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
S32.51 Fracture of pubis (open)	0.000	0.999	0.001
B37.8 Candidiasis of other sites	0.000	0.999	0.001
D58.2 Other haemoglobinopathies	0.001	0.999	0.000
R68.3 Clubbing of fingers	0.000	0.999	0.001
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M24.51 Contracture of joint (Shoulder region)	0.000	0.999	0.001
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.999	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.999	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.999	0.000
I35.8 Other aortic valve disorders	0.000	0.999	0.001
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
W45.9 Unspecified place	0.001	0.999	0.000
W45.0 Home	0.001	0.999	0.000
W45.7 Farm	0.001	0.999	0.000
W45.3 Sports and athletics area	0.001	0.999	0.000
W45.2 School, other institution and public administrative area	0.001	0.999	0.000
W45.1 Residential institution	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.999	0.001
Z35.5 Supervision of elderly primigravida	0.000	0.999	0.001
D57 Sickle-cell disorders	0.001	0.999	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.999	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.999	0.001
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.999	0.001
K09.2 Other cysts of jaw	0.001	0.999	0.000
N18.8 Other chronic renal failure	0.000	0.999	0.001
D55 Anaemia due to enzyme disorders	0.001	0.999	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.999	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.999	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.001	0.999	0.000
R78.0 Finding of alcohol in blood	0.001	0.999	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.999	0.001
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.999	0.001
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.999	0.001
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.999	0.001
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.999	0.001
M24.59 Contracture of joint (Site unspecified)	0.000	0.999	0.001
M24.58 Contracture of joint (Other)	0.000	0.999	0.001
M24.53 Contracture of joint (Forearm)	0.000	0.999	0.001
M24.52 Contracture of joint (Upper arm)	0.000	0.999	0.001
M24.50 Contracture of joint (Multiple sites)	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
C90.0 Multiple myeloma	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.000	0.999	0.001
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.000	0.999	0.001
D56 Thalassaemia	0.001	0.999	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M71.06 Abscess of bursa (Lower leg)	0.001	0.999	0.000
W45.09 Foreign body or object entering through skin: Home: During unspecified activity	0.001	0.999	0.000
W45.03 Foreign body or object entering through skin; Home; While engaged in other types of work	0.001	0.999	0.000
W45.99 Foreign body or object entering through skin; Unspecified place ;During unspecified activity	0.001	0.999	0.000
M54.8 Other dorsalgia	0.001	0.999	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.999	0.000
R68 Other general symptoms and signs	0.000	0.999	0.001
X50 Overexertion and strenuous or repetitive movements	0.001	0.999	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.000	0.999	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000
D57.3 Sickle-cell trait	0.001	0.999	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.999	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.999	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.999	0.001
S70.0 Contusion of hip	0.000	0.999	0.001
T23.7 Corrosion of third degree of wrist and hand	0.001	0.999	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.999	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.999	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.999	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.001	0.999	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.001	0.999	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.999	0.001
K65.9 Peritonitis, unspecified	0.001	0.999	0.000
O32.6 Maternal care for compound presentation	0.001	0.999	0.000
I85 Oesophageal varices	0.001	0.999	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.999	0.001
M60.99 Myositis, unspecified (Site unspecified)	0.000	0.999	0.001
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
D56.0 Alpha thalassaemia	0.001	0.999	0.000
X50.4 Street and highway	0.001	0.999	0.000
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
F21 Schizotypal disorder	0.001	0.999	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.001	0.999	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.001	0.999	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.001	0.999	0.000
M54.82 Other dorsalgia (Cervical region)	0.001	0.999	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.001	0.999	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.001	0.999	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.001	0.999	0.000
M67.47 Ganglion, ankle and foot	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.999	0.000
R68.1 Nonspecific symptoms peculiar to infancy	0.000	0.999	0.001
X50.9 Unspecified place	0.001	0.999	0.000
X50.8 Other specified place	0.001	0.999	0.000
X50.5 Trade and service area	0.001	0.999	0.000
X50.3 Sports and athletics area	0.001	0.999	0.000
X50.0 Home	0.001	0.999	0.000
X50.7 Farm	0.001	0.999	0.000
X50.1 Residential institution	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.999	0.001
M54.84 Other dorsalgia (Thoracic region)	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.999	0.000
C48.2 Peritoneum, unspecified	0.000	0.999	0.001
G25.1 Drug-induced tremor	0.001	0.999	0.000
J05.1 Acute epiglottitis	0.001	0.999	0.000
M41.5 Other secondary scoliosis	0.001	0.999	0.000
S32.2 Fracture of coccyx	0.000	0.999	0.001
S43.1 Dislocation of acromioclavicular joint	0.000	0.999	0.001
T23.2 Burn of second degree of wrist and hand	0.001	0.999	0.000
Z45.8 Adjustment and management of other implanted devices	0.001	0.999	0.000
Z51.3 Blood transfusion without reported diagnosis	0.001	0.999	0.000
X50.09 Overexertion and strenuous or repetitive movements; Home; During unspecified activity	0.001	0.999	0.000
X50.04 Overexertion and strenuous or repetitive movements; Home; While resting, sleeping, eating or engaging in other vital activities	0.001	0.999	0.000
X50.30 Overexertion and strenuous or repetitive movements; Sports and athletics area;While engaged in sports activity	0.001	0.999	0.000
X50.52 Overexertion and strenuous or repetitive movements, Trade and service area, While working for income	0.001	0.999	0.000
X50.89 Overexertion and strenuous or repetitive movements: Other specified places: During unspecified activity	0.001	0.999	0.000
X50.82 Overexertion and strenuous or repetitive movements; Other specified places ;While working for income	0.001	0.999	0.000
X50.99 Overexertion and strenuous or repetitive movements; Unspecified place ;During unspecified activity	0.001	0.999	0.000
X50.90 Overexertion and strenuous or repetitive movements: Unspecified place: While engaged in sports activity	0.001	0.999	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.001	0.999	0.000
I49.3 Ventricular premature depolarisation	0.000	0.999	0.001
M85.8 Other specified disorders of bone density and structure	0.001	0.999	0.000
D61 Other aplastic anaemias	0.001	0.999	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.001	0.999	0.000
M41.59 Other secondary scoliosis (Site unspecified)	0.001	0.999	0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M41.57 Other secondary scoliosis (Lumbosacral region)	0.001	0.999	0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.001	0.999	0.000
M41.54 Other secondary scoliosis (Thoracic region)	0.001	0.999	0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.001	0.999	0.000
M41.52 Other secondary scoliosis (Cervical region)	0.001	0.999	0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.001	0.999	0.000
M54.86 Other dorsalgia (Lumbar region)	0.001	0.999	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.999	0.001
S32.21 Fracture of coccyx (open)	0.000	0.999	0.001
S32.20 Fracture of coccyx (closed)	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.001	0.999	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
I77.2 Rupture of artery	0.000	0.999	0.001
J02.8 Acute pharyngitis due to other specified organisms	0.001	0.999	0.000
M65.8 Other synovitis and tenosynovitis	0.001	0.999	0.000
T92.1 Sequelae of fracture of arm	0.000	0.999	0.001
Z60.2 Living alone	0.001	0.999	0.000
R54 Senility	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D61.8 Other specified aplastic anaemias	0.001	0.999	0.000
D61.3 Idiopathic aplastic anaemia	0.001	0.999	0.000
D61.2 Aplastic anaemia due to other external agents	0.001	0.999	0.000
G93.0 Cerebral cysts	0.000	0.999	0.001
K56.4 Other impaction of intestine	0.001	0.999	0.000
S32.3 Fracture of ilium	0.000	0.999	0.001
Z43.4 Attention to other artificial openings of digestive tract	0.001	0.999	0.000
Z98.8 Other specified postsurgical states	0.001	0.999	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.001	0.999	0.000
T20 Burn and corrosion of head and neck	0.001	0.999	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.001	0.999	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.001	0.999	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.001	0.999	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.001	0.999	0.000
S32.31 Fracture of ilium (open)	0.000	0.999	0.001
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.001	0.999	0.000
C02.9 Tongue, unspecified	0.001	0.999	0.000
C02.4 Lingual tonsil	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations