TreeWAS – Variant ID: rs2120335

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.927	0.073	0.000
I83 Varicose veins of lower extremities	0.557	0.443	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.513	0.487	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.419	0.581	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.243	0.757	0.001
K86.1 Other chronic pancreatitis	0.000	0.966	0.034
K86 Other diseases of pancreas	0.000	0.969	0.031
C67 Malignant neoplasm of bladder	0.000	0.970	0.030
K86.8 Other specified diseases of pancreas	0.000	0.971	0.029
K86.2 Cyst of pancreas	0.000	0.972	0.028
C67.5 Bladder neck	0.000	0.972	0.028
C67.1 Dome of bladder	0.000	0.973	0.027
C67.0 Trigone of bladder	0.000	0.973	0.027
C67.4 Posterior wall of bladder	0.000	0.973	0.027
C67.8 Overlapping lesion of bladder	0.000	0.973	0.027
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.975	0.025
K86.3 Pseudocyst of pancreas	0.000	0.976	0.024
I86.8 Varicose veins of other specified sites	0.024	0.976	0.000
C67.2 Lateral wall of bladder	0.000	0.978	0.022
C67.9 Bladder, unspecified	0.000	0.978	0.022
C67.7 Urachus	0.000	0.978	0.021
C67.3 Anterior wall of bladder	0.000	0.979	0.021
K86.9 Disease of pancreas, unspecified	0.000	0.979	0.021
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.020	0.980	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.981	0.019
I86 Varicose veins of other sites	0.019	0.981	0.000
I88 Nonspecific lymphadenitis	0.018	0.982	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.018	0.982	0.000
C67.6 Ureteric orifice	0.000	0.983	0.017
N30.2 Other chronic cystitis	0.000	0.984	0.016
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.014	0.986	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.014	0.986	0.000
I86.3 Vulval varices	0.014	0.986	0.000
I86.0 Sublingual varices	0.013	0.986	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.013	0.986	0.000
I89.1 Lymphangitis	0.013	0.987	0.000
T17.2 Foreign body in pharynx	0.000	0.988	0.012
I86.2 Pelvic varices	0.012	0.988	0.000
I88.8 Other nonspecific lymphadenitis	0.012	0.988	0.000
I85 Oesophageal varices	0.012	0.988	0.000
G80 Infantile cerebral palsy	0.000	0.988	0.012
C64-C68 Malignant neoplasms of urinary tract	0.000	0.989	0.011
I89.0 Lymphoedema, not elsewhere classified	0.011	0.989	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.010	0.990	0.000
I81 Portal vein thrombosis	0.010	0.990	0.000
T17 Foreign body in respiratory tract	0.000	0.990	0.010
G80.2 Infantile hemiplegia	0.000	0.990	0.010
I67.9 Cerebrovascular disease, unspecified	0.000	0.990	0.010
S64.4 Injury of digital nerve of other finger	0.010	0.990	0.000
T18.1 Foreign body in oesophagus	0.000	0.991	0.009
G80.1 Spastic diplegia	0.000	0.991	0.009
I85.9 Oesophageal varices without bleeding	0.009	0.991	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.991	0.009
O42.9 Premature rupture of membranes, unspecified	0.009	0.991	0.000
G80.4 Ataxic cerebral palsy	0.000	0.991	0.008
G80.3 Dyskinetic cerebral palsy	0.000	0.991	0.008
C66 Malignant neoplasm of ureter	0.000	0.992	0.008
G80.8 Other infantile cerebral palsy	0.000	0.992	0.008
I86.4 Gastric varices	0.008	0.992	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.000	0.992	0.008
T18 Foreign body in alimentary tract	0.000	0.992	0.008
G80.0 Spastic cerebral palsy	0.000	0.992	0.008
C65 Malignant neoplasm of renal pelvis	0.000	0.992	0.008
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.992	0.008
T15-T19 Effects of foreign body entering through natural orifice	0.000	0.992	0.008
T17.5 Foreign body in bronchus	0.000	0.992	0.008
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.007	0.992	0.000
T17.4 Foreign body in trachea	0.000	0.993	0.007
T17.1 Foreign body in nostril	0.000	0.993	0.007
T17.0 Foreign body in nasal sinus	0.000	0.993	0.007
C68.0 Urethra	0.000	0.993	0.007
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.993	0.007
L60.0 Ingrowing nail	0.007	0.993	0.000
I67 Other cerebrovascular diseases	0.000	0.993	0.007
I82 Other venous embolism and thrombosis	0.007	0.993	0.000
C68.9 Urinary organ, unspecified	0.000	0.993	0.006
C68.8 Overlapping lesion of urinary organs	0.000	0.993	0.006
C68.1 Paraurethral glands	0.000	0.993	0.006
T18.0 Foreign body in mouth	0.000	0.993	0.006
T16 Foreign body in ear	0.000	0.994	0.006
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.994	0.006
T18.4 Foreign body in colon	0.000	0.994	0.006
T18.2 Foreign body in stomach	0.000	0.994	0.006
T19 Foreign body in genito-urinary tract	0.000	0.994	0.006
T18.3 Foreign body in small intestine	0.000	0.994	0.006
T17.3 Foreign body in larynx	0.000	0.994	0.006
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.994	0.006
K22.9 Disease of oesophagus, unspecified	0.000	0.994	0.006
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.994	0.006
I69.3 Sequelae of cerebral infarction	0.000	0.994	0.006
O42 Premature rupture of membranes	0.006	0.994	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.994	0.006
T18.5 Foreign body in anus and rectum	0.000	0.994	0.006
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.006	0.994	0.000
I67.2 Cerebral atherosclerosis	0.000	0.994	0.006
I82.3 Embolism and thrombosis of renal vein	0.005	0.994	0.000
I85.0 Oesophageal varices with bleeding	0.005	0.994	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.994	0.006
I60 Subarachnoid haemorrhage	0.000	0.994	0.006
I61 Intracerebral haemorrhage	0.000	0.995	0.005
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.995	0.005
I82.2 Embolism and thrombosis of vena cava	0.005	0.995	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.995	0.005
I67.5 Moyamoya disease	0.000	0.995	0.005
I67.4 Hypertensive encephalopathy	0.000	0.995	0.005
I67.3 Progressive vascular leukoencephalopathy	0.000	0.995	0.005
L60 Nail disorders	0.005	0.995	0.000
I82.1 Thrombophlebitis migrans	0.005	0.995	0.000
I87 Other disorders of veins	0.005	0.995	0.001
I60.8 Other subarachnoid haemorrhage	0.000	0.995	0.005
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.995	0.005
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.995	0.005
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
T19.2 Foreign body in vulva and vagina	0.000	0.995	0.005
T19.1 Foreign body in bladder	0.000	0.995	0.005
I61.8 Other intracerebral haemorrhage	0.000	0.995	0.005
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.995	0.005
L60.8 Other nail disorders	0.005	0.995	0.000
I60-I69 Cerebrovascular diseases	0.000	0.995	0.005
T19.9 Foreign body in genito-urinary tract, part unspecified	0.000	0.995	0.004
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.000	0.995	0.004
T19.3 Foreign body in uterus [any part]	0.000	0.995	0.004
T19.0 Foreign body in urethra	0.000	0.995	0.004
G63.2 Diabetic polyneuropathy	0.000	0.995	0.005
T15 Foreign body on external eye	0.000	0.995	0.004
I69 Sequelae of cerebrovascular disease	0.000	0.995	0.005
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.995	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.005	0.995	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.996	0.004
I82.0 Budd-Chiari syndrome	0.004	0.996	0.000
L60.9 Nail disorder, unspecified	0.004	0.996	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.996	0.004
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.996	0.004
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.996	0.004
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.996	0.004
L60.3 Nail dystrophy	0.004	0.996	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.996	0.004
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.996	0.004
O42.2 Premature rupture of membranes, labour delayed by therapy	0.004	0.996	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.996	0.004
L60.1 Onycholysis	0.004	0.996	0.000
L60.2 Onychogryphosis	0.004	0.996	0.000
L60.5 Yellow nail syndrome	0.004	0.996	0.000
L60.4 Beau's lines	0.004	0.996	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.996	0.004
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.996	0.004
I87.0 Postphlebitic syndrome	0.003	0.996	0.001
I86.1 Scrotal varices	0.003	0.996	0.000
S64 Injury of nerves at wrist and hand level	0.004	0.996	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.996	0.004
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.004	0.996	0.000
I87.9 Disorder of vein, unspecified	0.003	0.996	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.996	0.004
T15.8 Foreign body in other and multiple parts of external eye	0.000	0.996	0.003
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.996	0.004
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.996	0.004
I87.8 Other specified disorders of veins	0.003	0.996	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.997	0.003
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
T15.0 Foreign body in cornea	0.000	0.997	0.003
N85.9 Noninflammatory disorder of uterus, unspecified	0.003	0.997	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.997	0.003
T15.1 Foreign body in conjunctival sac	0.000	0.997	0.003
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.997	0.003
G83 Other paralytic syndromes	0.000	0.997	0.003
E11.4 With neurological complications	0.000	0.997	0.003
H02.8 Other specified disorders of eyelid	0.003	0.997	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.997	0.003
S64.1 Injury of median nerve at wrist and hand level	0.003	0.997	0.000
T15.9 Foreign body on external eye, unspecified	0.000	0.997	0.003
G83.8 Other specified paralytic syndromes	0.000	0.997	0.003
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
G83.2 Monoplegia of upper limb	0.000	0.997	0.003
I82.9 Embolism and thrombosis of unspecified vein	0.003	0.997	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.003	0.997	0.000
S64.8 Injury of other nerves at wrist and hand level	0.003	0.997	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.003	0.997	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.997	0.003
N83.0 Follicular cyst of ovary	0.003	0.997	0.000
J81 Pulmonary oedema	0.003	0.997	0.000
F52.2 Failure of genital response	0.003	0.997	0.000
I65.1 Occlusion and stenosis of basilar artery	0.000	0.997	0.003
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.997	0.003
G83.9 Paralytic syndrome, unspecified	0.000	0.997	0.003
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.997	0.003
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.997	0.003
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.997	0.003
I87.1 Compression of vein	0.002	0.997	0.001
Z48.9 Surgical follow-up care, unspecified	0.000	0.997	0.003
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.002
G83.5 Locked-in syndrome	0.000	0.997	0.002
G83.3 Monoplegia, unspecified	0.000	0.997	0.002
G83.1 Monoplegia of lower limb	0.000	0.997	0.003
G83.0 Diplegia of upper limbs	0.000	0.997	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.997	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.997	0.002
S64.3 Injury of digital nerve of thumb	0.002	0.997	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.997	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.997	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.997	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
R94.5 Abnormal results of liver function studies	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
K31.5 Obstruction of duodenum	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
G72.9 Myopathy, unspecified	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
N39.4 Other specified urinary incontinence	0.000	0.998	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.002
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.998	0.002
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
K63.1 Perforation of intestine (nontraumatic)	0.000	0.998	0.002
G81 Hemiplegia	0.000	0.998	0.002
X51.9 Unspecified place	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Z48 Other surgical follow-up care	0.000	0.998	0.002
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.000	0.998	0.002
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
M20.5 Other deformities of toe(s) (acquired)	0.000	0.998	0.002
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.001	0.998	0.000
M65.34 Trigger finger-Hand	0.000	0.998	0.002
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
F52.0 Lack or loss of sexual desire	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
C34.0 Main bronchus	0.000	0.998	0.002
N30 Cystitis	0.000	0.998	0.002
I95.1 Orthostatic hypotension	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
O43.1 Malformation of placenta	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.000	0.998	0.002
K31.8 Other specified diseases of stomach and duodenum	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
B00.1 Herpesviral vesicular dermatitis	0.000	0.998	0.002
Z40 Prophylactic surgery	0.000	0.998	0.002
Q38.7 Pharyngeal pouch	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.998	0.001
E13.9 Without complications	0.000	0.998	0.002
G72.0 Drug-induced myopathy	0.000	0.998	0.001
N30.4 Irradiation cystitis	0.000	0.998	0.002
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
G72 Other myopathies	0.000	0.998	0.002
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.001	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.998	0.002
C53.0 Endocervix	0.000	0.998	0.002
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.001
M85.4 Solitary bone cyst	0.001	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
K31 Other diseases of stomach and duodenum	0.000	0.998	0.002
S82.21 Fracture of shaft of tibia (open)	0.000	0.998	0.001
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.998	0.000
G06.2 Extradural and subdural abscess, unspecified	0.001	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.001	0.999	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.999	0.001
D61.1 Drug-induced aplastic anaemia	0.000	0.999	0.001
G83.4 Cauda equina syndrome	0.000	0.999	0.001
J31.2 Chronic pharyngitis	0.001	0.999	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.999	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.999	0.001
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.999	0.001
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.999	0.001
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.000	0.999	0.001
X60.8 Other specified place	0.001	0.999	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.001	0.999	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.001	0.999	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.001	0.999	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.001	0.999	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.001	0.999	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.001	0.999	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.001	0.999	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.001	0.999	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.999	0.001
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.999	0.001
G72.3 Periodic paralysis	0.000	0.999	0.001
G72.2 Myopathy due to other toxic agents	0.000	0.999	0.001
M94.8 Other specified disorders of cartilage	0.000	0.999	0.001
M85 Other disorders of bone density and structure	0.001	0.999	0.000
G72.1 Alcoholic myopathy	0.000	0.999	0.001
K31.3 Pylorospasm, not elsewhere classified	0.000	0.999	0.001
K31.0 Acute dilatation of stomach	0.000	0.999	0.001
O43.9 Placental disorder, unspecified	0.001	0.999	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
M85.49 Solitary bone cyst (Site unspecified)	0.001	0.999	0.000
M85.48 Solitary bone cyst (Other)	0.001	0.999	0.000
M85.46 Solitary bone cyst (Lower leg)	0.001	0.999	0.000
M85.44 Solitary bone cyst (Hand)	0.001	0.999	0.000
M85.43 Solitary bone cyst (Forearm)	0.001	0.999	0.000
M85.42 Solitary bone cyst (Upper arm)	0.001	0.999	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.001	0.999	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.001	0.999	0.000
C71.1 Frontal lobe	0.000	0.999	0.001
F50.0 Anorexia nervosa	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.001	0.999	0.000
D61 Other aplastic anaemias	0.000	0.999	0.001
F50 Eating disorders	0.001	0.999	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.999	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.999	0.001
S52.51 Fracture of lower end of radius (open)	0.000	0.999	0.001
K31.2 Hourglass stricture and stenosis of stomach	0.000	0.999	0.001
M85.6 Other cyst of bone	0.001	0.999	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.999	0.001
Z40.9 Prophylactic surgery, unspecified	0.000	0.999	0.001
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.999	0.001
D23.0 Skin of lip	0.001	0.999	0.000
N30.9 Cystitis, unspecified	0.000	0.999	0.001
N30.1 Interstitial cystitis (chronic)	0.000	0.999	0.001
Z03.2 Observation for suspected mental and behavioural disorders	0.000	0.999	0.001
Z48.0 Attention to surgical dressings and sutures	0.000	0.999	0.001
M85.68 Other cyst of bone (Other)	0.001	0.999	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.999	0.001
H73.8 Other specified disorders of tympanic membrane	0.001	0.999	0.000
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
T90.5 Sequelae of intracranial injury	0.001	0.999	0.000
F55 Abuse of non-dependence-producing substances	0.001	0.999	0.000
F50.2 Bulimia nervosa	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.001	0.999	0.000
K31.6 Fistula of stomach and duodenum	0.000	0.999	0.001
M34.1 CR(E)ST syndrome	0.000	0.999	0.001
O20.0 Threatened abortion	0.001	0.999	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.001	0.999	0.000
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
Z04.3 Examination and observation following other accident	0.000	0.999	0.001
I80 Phlebitis and thrombophlebitis	0.001	0.999	0.000
O43 Placental disorders	0.001	0.999	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.999	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.999	0.001
M65.83 Other synovitis and tenosynovitis (Forearm)	0.000	0.999	0.001
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.999	0.001
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.999	0.001
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.999	0.001
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.999	0.001
D44.8 Pluriglandular involvement	0.000	0.999	0.001
G91.1 Obstructive hydrocephalus	0.000	0.999	0.001
M85.5 Aneurysmal bone cyst	0.001	0.999	0.000
M85.3 Osteitis condensans	0.001	0.999	0.000
M85.1 Skeletal fluorosis	0.001	0.999	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.999	0.000
T90.1 Sequelae of open wound of head	0.001	0.999	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
D61.8 Other specified aplastic anaemias	0.000	0.999	0.001
D61.3 Idiopathic aplastic anaemia	0.000	0.999	0.001
D61.2 Aplastic anaemia due to other external agents	0.000	0.999	0.001
F50.9 Eating disorder, unspecified	0.001	0.999	0.000
F50.8 Other eating disorders	0.001	0.999	0.000
F50.5 Vomiting associated with other psychological disturbances	0.001	0.999	0.000
F50.4 Overeating associated with other psychological disturbances	0.001	0.999	0.000
F50.3 Atypical bulimia nervosa	0.001	0.999	0.000
F50.1 Atypical anorexia nervosa	0.001	0.999	0.000
X58.9 Unspecified place	0.000	0.999	0.001
M85.69 Other cyst of bone (Site unspecified)	0.001	0.999	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.001	0.999	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.999	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.999	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.999	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.999	0.001
N50.0 Atrophy of testis	0.000	0.999	0.001
B02.9 Zoster without complication	0.000	0.999	0.001
D44.1 Adrenal gland	0.000	0.999	0.001
H70.9 Mastoiditis, unspecified	0.001	0.999	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.999	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.999	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
M85.19 Skeletal fluorosis (Site unspecified)	0.001	0.999	0.000
M85.18 Skeletal fluorosis (Other)	0.001	0.999	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.001	0.999	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.001	0.999	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.001	0.999	0.000
M85.14 Skeletal fluorosis (Hand)	0.001	0.999	0.000
M85.13 Skeletal fluorosis (Forearm)	0.001	0.999	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.001	0.999	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.001	0.999	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.001	0.999	0.000
M85.39 Osteitis condensans (Site unspecified)	0.001	0.999	0.000
M85.38 Osteitis condensans (Other)	0.001	0.999	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.001	0.999	0.000
M85.36 Osteitis condensans (Lower leg)	0.001	0.999	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.001	0.999	0.000
M85.34 Osteitis condensans (Hand)	0.001	0.999	0.000
M85.33 Osteitis condensans (Forearm)	0.001	0.999	0.000
M85.32 Osteitis condensans (Upper arm)	0.001	0.999	0.000
M85.31 Osteitis condensans (Shoulder region)	0.001	0.999	0.000
M85.30 Osteitis condensans (Multiple sites)	0.001	0.999	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.001	0.999	0.000
M85.58 Aneurysmal bone cyst (Other)	0.001	0.999	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.001	0.999	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.001	0.999	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.001	0.999	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.001	0.999	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.001	0.999	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.001	0.999	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.001	0.999	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.999	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.000	0.999	0.001
G72.8 Other specified myopathies	0.000	0.999	0.001
M65.8 Other synovitis and tenosynovitis	0.000	0.999	0.001
O43.2 Morbidly adherent placenta	0.001	0.999	0.000
R44.1 Visual hallucinations	0.001	0.999	0.000
Z40.8 Other prophylactic surgery	0.001	0.999	0.001
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.999	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.001	0.999	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.999	0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.001	0.999	0.000
M85.2 Hyperostosis of skull	0.001	0.999	0.000
S50.0 Contusion of elbow	0.000	0.999	0.001
G91 Hydrocephalus	0.000	0.999	0.001
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.000	0.999	0.001
E14.4 With neurological complications	0.000	0.999	0.001
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.999	0.000
K11.6 Mucocele of salivary gland	0.000	0.999	0.001
R94.4 Abnormal results of kidney function studies	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.001	0.999	0.000
G82 Paraplegia and tetraplegia	0.000	0.999	0.001
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.999	0.001
S82.20 Fracture of shaft of tibia (closed)	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations