TreeWAS – Variant ID: rs2126200

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T42.4 Benzodiazepines	0.000	0.978	0.022
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.979	0.021
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.979	0.021
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.982	0.018
S80.9 Superficial injury of lower leg, unspecified	0.000	0.983	0.017
T42.1 Iminostilbenes	0.000	0.984	0.016
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.984	0.015
T42.2 Succinimides and oxazolidinediones	0.000	0.984	0.015
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.985	0.015
T42.3 Barbiturates	0.000	0.985	0.015
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.985	0.015
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.015	0.985	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.986	0.014
T42.0 Hydantoin derivatives	0.000	0.986	0.014
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.987	0.013
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.987	0.013
T45.0 Antiallergic and antiemetic drugs	0.000	0.987	0.013
F41 Other anxiety disorders	0.013	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.987	0.013
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.987	0.013
S81 Open wound of lower leg	0.000	0.987	0.013
T45.2 Vitamins, not elsewhere classified	0.000	0.988	0.012
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.988	0.012
F42.9 Obsessive-compulsive disorder, unspecified	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.988	0.012
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.988	0.012
T39.0 Salicylates	0.000	0.988	0.012
F41.2 Mixed anxiety and depressive disorder	0.012	0.988	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.988	0.012
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.988	0.012
Z57.2 Occupational exposure to dust	0.012	0.988	0.000
S80 Superficial injury of lower leg	0.000	0.988	0.012
F42 Obsessive-compulsive disorder	0.011	0.989	0.000
T45.5 Anticoagulants	0.000	0.989	0.011
F41.9 Anxiety disorder, unspecified	0.011	0.989	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.989	0.011
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.989	0.011
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.989	0.011
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.989	0.011
T45.8 Other primarily systemic and haematological agents	0.000	0.989	0.011
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.989	0.011
T45.6 Fibrinolysis-affecting drugs	0.000	0.989	0.011
T45.4 Iron and its compounds	0.000	0.989	0.011
T45.3 Enzymes, not elsewhere classified	0.000	0.989	0.011
S81.7 Multiple open wounds of lower leg	0.000	0.989	0.011
F40-F48 Neurotic, stress-related and somatoform disorders	0.011	0.989	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.989	0.011
T50.8 Diagnostic agents	0.000	0.989	0.011
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.989	0.011
S80-S89 Injuries to the knee and lower leg	0.000	0.990	0.010
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.990	0.010
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.990	0.010
T50.4 Drugs affecting uric acid metabolism	0.000	0.990	0.010
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.990	0.010
S89.9 Unspecified injury of lower leg	0.000	0.990	0.010
T36 Poisoning by systemic antibiotics	0.000	0.990	0.010
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.990	0.010
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.990	0.010
T37.5 Antiviral drugs	0.000	0.990	0.010
T37.4 Anthelminthics	0.000	0.990	0.010
T37.3 Other antiprotozoal drugs	0.000	0.990	0.010
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.990	0.010
T37.1 Antimycobacterial drugs	0.000	0.990	0.010
T37.0 Sulphonamides	0.000	0.990	0.010
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.990	0.010
F45 Somatoform disorders	0.010	0.990	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.990	0.010
T50.5 Appetite depressants	0.000	0.990	0.010
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.990	0.010
T50.1 Loop [high-ceiling] diuretics	0.000	0.990	0.010
T50.0 Mineralocorticoids and their antagonists	0.000	0.990	0.010
S89 Other and unspecified injuries of lower leg	0.000	0.990	0.010
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.990	0.010
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.991	0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.991	0.009
S82.30 Fracture of lower end of tibia (closed)	0.000	0.991	0.009
S81.9 Open wound of lower leg, part unspecified	0.000	0.991	0.009
T43.6 Psychostimulants with abuse potential	0.000	0.991	0.009
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.991	0.009
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.991	0.009
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.991	0.009
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.991	0.009
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.991	0.009
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.991	0.009
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.991	0.009
T44.0 Anticholinesterase agents	0.000	0.991	0.009
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.991	0.009
F41.3 Other mixed anxiety disorders	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.991	0.009
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.991	0.009
S80.7 Multiple superficial injuries of lower leg	0.000	0.991	0.009
C09.9 Tonsil, unspecified	0.000	0.991	0.009
D12.2 Ascending colon	0.000	0.991	0.009
T49.9 Topical agent, unspecified	0.000	0.991	0.008
T49.8 Other topical agents	0.000	0.991	0.008
T49.7 Dental drugs, topically applied	0.000	0.991	0.008
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.991	0.008
T49.5 Ophthalmological drugs and preparations	0.000	0.991	0.008
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.991	0.008
T49.3 Emollients, demulcents and protectants	0.000	0.991	0.008
T49.2 Local astringents and local detergents	0.000	0.991	0.008
T49.1 Antipruritics	0.000	0.991	0.008
F42.0 Predominantly obsessional thoughts or ruminations	0.008	0.991	0.000
F42.8 Other obsessive-compulsive disorders	0.008	0.992	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.008	0.992	0.000
S81.0 Open wound of knee	0.000	0.992	0.008
F45.8 Other somatoform disorders	0.008	0.992	0.000
T41.5 Therapeutic gases	0.000	0.992	0.008
T41.4 Anaesthetic, unspecified	0.000	0.992	0.008
T41.3 Local anaesthetics	0.000	0.992	0.008
T41.2 Other and unspecified general anaesthetics	0.000	0.992	0.008
T41.1 Intravenous anaesthetics	0.000	0.992	0.008
T41.0 Inhaled anaesthetics	0.000	0.992	0.008
F42.2 Mixed obsessional thoughts and acts	0.008	0.992	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.992	0.008
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.992	0.008
T47.7 Emetics	0.000	0.992	0.008
T47.5 Digestants	0.000	0.992	0.008
T47.4 Other laxatives	0.000	0.992	0.008
T47.3 Saline and osmotic laxatives	0.000	0.992	0.008
T47.2 Stimulant laxatives	0.000	0.992	0.008
F40 Phobic anxiety disorders	0.008	0.992	0.000
D50.8 Other iron deficiency anaemias	0.000	0.992	0.008
F48 Other neurotic disorders	0.008	0.992	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.992	0.008
T39.2 Pyrazolone derivatives	0.000	0.992	0.008
F41.8 Other specified anxiety disorders	0.008	0.992	0.000
F41.1 Generalised anxiety disorder	0.008	0.992	0.000
F45.9 Somatoform disorder, unspecified	0.008	0.992	0.000
F45.4 Persistent somatoform pain disorder	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.992	0.008
T48.5 Anti-common-cold drugs	0.000	0.992	0.008
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.992	0.008
Z57 Occupational exposure to risk-factors	0.008	0.992	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.992	0.008
S80.0 Contusion of knee	0.000	0.992	0.008
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.992	0.008
T48.4 Expectorants	0.000	0.992	0.008
T48.3 Antitussives	0.000	0.992	0.008
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.992	0.008
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.992	0.008
T48.0 Oxytocic drugs	0.000	0.992	0.008
T47.6 Antidiarrhoeal drugs	0.000	0.992	0.008
S88 Traumatic amputation of lower leg	0.000	0.992	0.008
S85 Injury of blood vessels at lower leg level	0.000	0.992	0.008
F45.0 Somatisation disorder	0.008	0.992	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.992	0.008
C50.3 Lower-inner quadrant of breast	0.000	0.992	0.008
T47.0 Histamine H(2)-receptor antagonists	0.000	0.992	0.007
S84 Injury of nerves at lower leg level	0.000	0.992	0.008
S82.3 Fracture of lower end of tibia	0.000	0.992	0.008
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.992	0.007
T38.9 Other and unspecified hormone antagonists	0.000	0.992	0.007
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.992	0.007
T38.7 Androgens and anabolic congeners	0.000	0.992	0.007
T38.5 Other oestrogens and progestogens	0.000	0.992	0.007
T38.4 Oral contraceptives	0.000	0.992	0.007
T38.2 Antithyroid drugs	0.000	0.992	0.007
T38.0 Glucocorticoids and synthetic analogues	0.000	0.992	0.007
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.993	0.007
T36.9 Systemic antibiotic, unspecified	0.000	0.993	0.007
T36.8 Other systemic antibiotics	0.000	0.993	0.007
T36.7 Antifungal antibiotics, systemically used	0.000	0.993	0.007
T36.6 Rifamycins	0.000	0.993	0.007
T36.5 Aminoglycosides	0.000	0.993	0.007
T36.4 Tetracyclines	0.000	0.993	0.007
T36.2 Chloramphenicol group	0.000	0.993	0.007
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.993	0.007
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.993	0.007
F40.0 Agoraphobia	0.007	0.993	0.000
S82 Fracture of lower leg, including ankle	0.000	0.993	0.007
F45.1 Undifferentiated somatoform disorder	0.007	0.993	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.993	0.007
S89.7 Multiple injuries of lower leg	0.000	0.993	0.007
S89.1 Other specified injuries of lower leg	0.000	0.993	0.007
S89.0 Multiple injuries of lower leg	0.000	0.993	0.007
T36.3 Macrolides	0.000	0.993	0.007
F44 Dissociative [conversion] disorders	0.007	0.993	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.993	0.007
S82.6 Fracture of lateral malleolus	0.000	0.993	0.007
S82.60 Fracture of lateral malleolus (closed)	0.000	0.993	0.007
S87 Crushing injury of lower leg	0.000	0.993	0.007
F40.9 Phobic anxiety disorder, unspecified	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.993	0.007
T46.7 Peripheral vasodilators	0.000	0.993	0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.993	0.007
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.993	0.007
S80.8 Other superficial injuries of lower leg	0.000	0.993	0.007
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.993	0.007
Z57.5 Occupational exposure to toxic agents in other industries	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.993	0.007
F40.1 Social phobias	0.006	0.993	0.000
F48.9 Neurotic disorder, unspecified	0.006	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.006	0.993	0.000
F45.2 Hypochondriacal disorder	0.006	0.993	0.000
I84.5 External haemorrhoids without complication	0.007	0.993	0.000
F43 Reaction to severe stress, and adjustment disorders	0.006	0.993	0.000
T46.1 Calcium-channel blockers	0.000	0.994	0.006
T36.0 Penicillins	0.000	0.994	0.006
Y44.2 Anticoagulants	0.006	0.994	0.000
F40.8 Other phobic anxiety disorders	0.006	0.994	0.000
F48.8 Other specified neurotic disorders	0.006	0.994	0.000
F48.1 Depersonalisation-derealisation syndrome	0.006	0.994	0.000
N30.9 Cystitis, unspecified	0.006	0.994	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.994	0.006
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.994	0.006
Z57.9 Occupational exposure to unspecified risk-factor	0.006	0.994	0.000
Z57.7 Occupational exposure to vibration	0.006	0.994	0.000
Z57.6 Occupational exposure to extreme temperature	0.006	0.994	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.006	0.994	0.000
Z57.1 Occupational exposure to radiation	0.006	0.994	0.000
Z57.0 Occupational exposure to noise	0.006	0.994	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.994	0.006
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.994	0.006
F48.0 Neurasthenia	0.006	0.994	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.994	0.006
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.994	0.006
S85.8 Injury of other blood vessels at lower leg level	0.000	0.994	0.006
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.994	0.006
S85.5 Injury of popliteal vein	0.000	0.994	0.006
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.994	0.006
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.994	0.006
S85.2 Injury of peroneal artery	0.000	0.994	0.006
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.994	0.006
S85.0 Injury of popliteal artery	0.000	0.994	0.006
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.994	0.006
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.994	0.006
S88.0 Traumatic amputation at knee level	0.000	0.994	0.006
F44.0 Dissociative amnesia	0.006	0.994	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.994	0.006
S84.8 Injury of other nerves at lower leg level	0.000	0.994	0.006
S84.7 Injury of multiple nerves at lower leg level	0.000	0.994	0.006
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.994	0.006
S84.0 Injury of tibial nerve at lower leg level	0.000	0.994	0.006
I82.2 Embolism and thrombosis of vena cava	0.006	0.994	0.000
F45.3 Somatoform autonomic dysfunction	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.006	0.994	0.000
S83.7 Injury to multiple structures of knee	0.000	0.994	0.006
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.994	0.005
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.994	0.005
S83.0 Dislocation of patella	0.000	0.994	0.005
S82.61 Fracture of lateral malleolus (open)	0.000	0.994	0.005
D11.0 Parotid gland	0.005	0.995	0.000
S82.7 Multiple fractures of lower leg	0.000	0.995	0.005
F44.8 Other dissociative [conversion] disorders	0.005	0.995	0.000
F44.7 Mixed dissociative [conversion] disorders	0.005	0.995	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.005	0.995	0.000
F44.3 Trance and possession disorders	0.005	0.995	0.000
F44.2 Dissociative stupor	0.005	0.995	0.000
F44.1 Dissociative fugue	0.005	0.995	0.000
F43.9 Reaction to severe stress, unspecified	0.005	0.995	0.000
S87.0 Crushing injury of knee	0.000	0.995	0.005
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.995	0.005
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.995	0.005
I82.9 Embolism and thrombosis of unspecified vein	0.005	0.995	0.000
F44.4 Dissociative motor disorders	0.005	0.995	0.000
G56.2 Lesion of ulnar nerve	0.005	0.995	0.000
R44.1 Visual hallucinations	0.005	0.995	0.000
S83.1 Dislocation of knee	0.000	0.995	0.005
I82 Other venous embolism and thrombosis	0.005	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.995	0.005
F43.8 Other reactions to severe stress	0.005	0.995	0.000
F43.0 Acute stress reaction	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.995	0.005
F44.9 Dissociative [conversion] disorder, unspecified	0.005	0.995	0.000
S89.8 Other specified injuries of lower leg	0.000	0.995	0.005
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.995	0.005
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
F44.5 Dissociative convulsions	0.005	0.995	0.000
C09 Malignant neoplasm of tonsil	0.000	0.995	0.005
S82.9 Fracture of lower leg, part unspecified	0.000	0.995	0.005
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.005	0.995	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.995	0.004
S42.40 Fracture of lower end of humerus (closed)	0.000	0.995	0.005
I82.3 Embolism and thrombosis of renal vein	0.005	0.995	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.995	0.005
S82.86 Maisonneuve's fracture	0.000	0.995	0.004
J31.0 Chronic rhinitis	0.005	0.995	0.000
S82.5 Fracture of medial malleolus	0.000	0.996	0.004
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.996	0.004
S06.4 Epidural haemorrhage	0.000	0.996	0.004
S82.1 Fracture of upper end of tibia	0.000	0.996	0.004
F43.2 Adjustment disorders	0.004	0.996	0.000
S82.71 Multiple fractures of lower leg (open)	0.000	0.996	0.004
S82.70 Multiple fractures of lower leg (closed)	0.000	0.996	0.004
S82.4 Fracture of fibula alone	0.000	0.996	0.004
S82.31 Fracture of lower end of tibia (open)	0.000	0.996	0.004
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.996	0.004
S06.3 Focal brain injury	0.000	0.996	0.004
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.996	0.004
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.996	0.004
S82.0 Fracture of patella	0.000	0.996	0.004
S82.81 Fractures of other parts of lower leg (open)	0.000	0.996	0.004
S06 Intracranial injury	0.000	0.996	0.004
O81.4 Vacuum extractor delivery	0.004	0.996	0.000
T40.5 Cocaine	0.000	0.996	0.004
I82.1 Thrombophlebitis migrans	0.004	0.996	0.000
I82.0 Budd-Chiari syndrome	0.004	0.996	0.000
S86.0 Injury of Achilles tendon	0.000	0.996	0.004
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.996	0.004
S83.2 Tear of meniscus, current	0.000	0.996	0.004
T40.1 Heroin	0.000	0.996	0.004
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.996	0.004
T40.8 Lysergide [LSD]	0.000	0.996	0.004
T40.7 Cannabis (derivatives)	0.000	0.996	0.004
T40.3 Methadone	0.000	0.996	0.004
T40.0 Opium	0.000	0.996	0.004
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.996	0.004
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.996	0.004
C09.8 Overlapping lesion of tonsil	0.000	0.996	0.004
R46.8 Other symptoms and signs involving appearance and behaviour	0.004	0.996	0.000
S06.0 Concussion	0.000	0.996	0.004
D11 Benign neoplasm of major salivary glands	0.004	0.996	0.000
M51.8 Other specified intervertebral disk disorders	0.004	0.996	0.000
C09.0 Tonsillar fossa	0.000	0.996	0.003
S82.11 Fracture of upper end of tibia (open)	0.000	0.997	0.003
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.003
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.997	0.003
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
M65.34 Trigger finger-Hand	0.003	0.997	0.000
O47.9 False labour, unspecified	0.003	0.997	0.000
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
S06.2 Diffuse brain injury	0.000	0.997	0.003
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.003	0.997	0.000
D43.2 Brain, unspecified	0.000	0.997	0.003
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.997	0.003
S82.41 Fracture of fibula alone (open)	0.000	0.997	0.003
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
D11.7 Other major salivary glands	0.003	0.997	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.997	0.003
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.997	0.003
D11.9 Major salivary gland, unspecified	0.003	0.997	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.997	0.003
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.003	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
N48.4 Impotence of organic origin	0.000	0.997	0.003
R44.2 Other hallucinations	0.003	0.997	0.000
M51 Other intervertebral disk disorders	0.003	0.997	0.000
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.000	0.997	0.003
S82.01 Fracture of patella (open)	0.000	0.997	0.003
F43.1 Posttraumatic stress disorder	0.003	0.997	0.000
Z56 Problems related to employment and unemployment	0.003	0.997	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.997	0.003
Z64 Problems related to certain psychosocial circumstances	0.003	0.997	0.000
Z59 Problems related to housing and economic circumstances	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.997	0.003
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.003	0.997	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.003	0.997	0.000
M51.4 Schmorl's nodes	0.003	0.997	0.000
Z56.3 Stressful work schedule	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.000	0.997	0.003
S06.01 Concussion (with open intracranial wound)	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.000	0.997	0.003
Z63 Other problems related to primary support group, including family circumstances	0.003	0.997	0.000
B01.9 Varicella without complications	0.000	0.997	0.003
M51.9 Intervertebral disk disorder, unspecified	0.003	0.997	0.000
Z63.6 Dependent relative needing care at home	0.003	0.997	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.003	0.997	0.000
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
N64.1 Fat necrosis of breast	0.000	0.997	0.003
R44.0 Auditory hallucinations	0.003	0.997	0.000
Z56.0 Unemployment, unspecified	0.003	0.997	0.000
Z64.0 Problems related to unwanted pregnancy	0.003	0.997	0.000
J31.2 Chronic pharyngitis	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.000	0.997	0.002
F60.3 Emotionally unstable personality disorder	0.000	0.997	0.003
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.997	0.003
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
S42.4 Fracture of lower end of humerus	0.000	0.997	0.003
S06.9 Intracranial injury, unspecified	0.000	0.997	0.002
Z62 Other problems related to upbringing	0.003	0.997	0.000
Z55 Problems related to education and literacy	0.003	0.997	0.000
J31.1 Chronic nasopharyngitis	0.003	0.997	0.000
Z56.7 Other and unspecified problems related to employment	0.003	0.997	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.003	0.997	0.000
C51.9 Vulva, unspecified	0.000	0.997	0.003
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.997	0.000
Y44.7 Plasma substitutes	0.002	0.997	0.000
Y44.6 Natural blood and blood products	0.002	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.003	0.997	0.000
M62.6 Muscle strain	0.003	0.997	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.002	0.997	0.000
O81.3 Other and unspecified forceps delivery	0.002	0.997	0.000
Z59.1 Inadequate housing	0.002	0.997	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.997	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.997	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.997	0.002
Q87.4 Marfan's syndrome	0.002	0.997	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
Z56.5 Uncongenial work	0.002	0.998	0.000
Z56.4 Discord with boss and workmates	0.002	0.998	0.000
Z56.2 Threat of job loss	0.002	0.998	0.000
Z56.1 Change of job	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.002	0.998	0.000
Z59.7 Insufficient social insurance and welfare support	0.002	0.998	0.000
Z59.6 Low income	0.002	0.998	0.000
Z59.5 Extreme poverty	0.002	0.998	0.000
Z59.4 Lack of adequate food	0.002	0.998	0.000
Z59.3 Problems related to living in residential institution	0.002	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.998	0.000
Z59.0 Homelessness	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
M51.3 Other specified intervertebral disk degeneration	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
Z63.9 Problem related to primary support group, unspecified	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
Z63.3 Absence of family member	0.002	0.998	0.000
Z63.2 Inadequate family support	0.002	0.998	0.000
Z63.1 Problems in relationship with parents and in-laws	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.000	0.998	0.002
M62 Other disorders of muscle	0.002	0.998	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.002	0.998	0.000
Z55.8 Other problems relating to education and literacy	0.002	0.998	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.002	0.998	0.000
Z55.3 Underachievement in school	0.002	0.998	0.000
Z55.2 Failed examinations	0.002	0.998	0.000
Z55.1 Schooling unavailable and unattainable	0.002	0.998	0.000
Z55.0 Illiteracy and low-level literacy	0.002	0.998	0.000
Z62.9 Problem related to upbringing, unspecified	0.002	0.998	0.000
Z62.8 Other specified problems related to upbringing	0.002	0.998	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.002	0.998	0.000
Z62.5 Other problems related to neglect in upbringing	0.002	0.998	0.000
Z62.4 Emotional neglect of child	0.002	0.998	0.000
Z62.3 Hostility towards and scapegoating of child	0.002	0.998	0.000
Z62.2 Institutional upbringing	0.002	0.998	0.000
Z62.1 Parental overprotection	0.002	0.998	0.000
Z62.0 Inadequate parental supervision and control	0.002	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
Z63.7 Other stressful life events affecting family and household	0.002	0.998	0.000
M62.68 Muscle strain (Other)	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
N87.0 Mild cervical dysplasia	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.002	0.998	0.000
M62.69 Muscle strain (Site unspecified)	0.002	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.002	0.998	0.000
M62.64 Muscle strain (Hand)	0.002	0.998	0.000
M62.63 Muscle strain (Forearm)	0.002	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.002	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.002	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.002	0.998	0.000
I84.4 External haemorrhoids with other complications	0.000	0.998	0.002
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.002	0.998	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.002	0.998	0.000
Z61.8 Other negative life events in childhood	0.002	0.998	0.000
Z61.7 Personal frightening experience in childhood	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.002	0.998	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.002	0.998	0.000
Z61.2 Altered pattern of family relationships in childhood	0.002	0.998	0.000
Z61.1 Removal from home in childhood	0.002	0.998	0.000
Z61.0 Loss of love relationship in childhood	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
X41.9 Unspecified place	0.000	0.998	0.002
M19.03 Primary arthrosis of other joints (Forearm)	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
K62.4 Stenosis of anus and rectum	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations