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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2142705
log Bayes Factor = 19.1794
Chromosome 6   position 27,439,125  (GRCh37) Explore rs2142705 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.713 0.287
E10.9 Without complications
0.000 0.718 0.282
E10.6 With other specified complications
0.000 0.739 0.261
E10.5 With peripheral circulatory complications
0.000 0.743 0.257
E10.4 With neurological complications
0.000 0.743 0.257
E10.3 With ophthalmic complications
0.000 0.755 0.245
K90 Intestinal malabsorption
0.000 0.763 0.237
E10.1 With ketoacidosis
0.000 0.766 0.234
E10.8 With unspecified complications
0.000 0.770 0.230
E10.2 With renal complications
0.000 0.792 0.208
E10.0 With coma
0.000 0.793 0.207
E10.7 With multiple complications
0.000 0.794 0.206
E10-E14 Diabetes mellitus
0.000 0.820 0.180
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.824 0.176
K90.3 Pancreatic steatorrhoea
0.000 0.830 0.170
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.830 0.170
K90.1 Tropical sprue
0.000 0.830 0.170
K90.8 Other intestinal malabsorption
0.000 0.837 0.162
E83 Disorders of mineral metabolism
0.000 0.838 0.162
E13 Other specified diabetes mellitus
0.000 0.854 0.146
E12 Malnutrition-related diabetes mellitus
0.000 0.870 0.129
E13.9 Without complications
0.000 0.876 0.124
E11 Non-insulin-dependent diabetes mellitus
0.000 0.880 0.120
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.883 0.117
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.884 0.116
E83.8 Other disorders of mineral metabolism
0.000 0.884 0.116
E83.2 Disorders of zinc metabolism
0.000 0.884 0.116
E83.0 Disorders of copper metabolism
0.000 0.884 0.116
E70-E90 Metabolic disorders
0.000 0.884 0.116
E88 Other metabolic disorders
0.000 0.887 0.113
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.891 0.109
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.893 0.107
E13.8 With unspecified complications
0.000 0.895 0.105
E13.7 With multiple complications
0.000 0.895 0.105
E13.6 With other specified complications
0.000 0.895 0.105
E13.5 With peripheral circulatory complications
0.000 0.895 0.105
E13.4 With neurological complications
0.000 0.895 0.105
E13.2 With renal complications
0.000 0.895 0.105
E13.1 With ketoacidosis
0.000 0.895 0.105
E13.0 With coma
0.000 0.895 0.105
E16 Other disorders of pancreatic internal secretion
0.000 0.896 0.104
E14 Unspecified diabetes mellitus
0.000 0.898 0.102
E16.2 Hypoglycaemia, unspecified
0.000 0.898 0.102
E11.0 With coma
0.000 0.898 0.102
E13.3 With ophthalmic complications
0.000 0.898 0.102
E11.2 With renal complications
0.000 0.899 0.101
E11.4 With neurological complications
0.000 0.902 0.098
E14.3 With ophthalmic complications
0.000 0.904 0.096
E40-E46 Malnutrition
0.000 0.905 0.095
E11.1 With ketoacidosis
0.000 0.907 0.093
E12.9 Without complications
0.000 0.907 0.093
E12.8 With unspecified complications
0.000 0.907 0.093
E12.7 With multiple complications
0.000 0.907 0.093
E12.6 With other specified complications
0.000 0.907 0.093
E12.5 With peripheral circulatory complications
0.000 0.907 0.093
E12.4 With neurological complications
0.000 0.907 0.093
E12.3 With ophthalmic complications
0.000 0.907 0.093
E12.2 With renal complications
0.000 0.907 0.093
E12.1 With ketoacidosis
0.000 0.907 0.093
E12.0 With coma
0.000 0.907 0.093
E88.8 Other specified metabolic disorders
0.000 0.910 0.090
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.910 0.090
E88.2 Lipomatosis, not elsewhere classified
0.000 0.911 0.089
E85 Amyloidosis
0.000 0.912 0.088
E11.8 With unspecified complications
0.000 0.912 0.088
E11.5 With peripheral circulatory complications
0.000 0.913 0.087
E11.7 With multiple complications
0.000 0.913 0.086
E88.3 Tumour lysis syndrome
0.000 0.915 0.085
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.915 0.085
E84 Cystic fibrosis
0.000 0.917 0.083
E77 Disorders of glycoprotein metabolism
0.000 0.917 0.083
E76 Disorders of glycosaminoglycan metabolism
0.000 0.917 0.083
E72 Other disorders of amino-acid metabolism
0.000 0.917 0.083
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.917 0.083
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.917 0.083
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.920 0.080
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.920 0.080
E46 Unspecified protein-energy malnutrition
0.000 0.920 0.080
E15 Nondiabetic hypoglycaemic coma
0.000 0.921 0.078
E83.3 Disorders of phosphorus metabolism
0.000 0.922 0.078
E70 Disorders of aromatic amino-acid metabolism
0.000 0.922 0.078
E14.5 With peripheral circulatory complications
0.000 0.923 0.077
E11.6 With other specified complications
0.000 0.924 0.076
E88.9 Metabolic disorder, unspecified
0.000 0.924 0.075
K90.9 Intestinal malabsorption, unspecified
0.000 0.925 0.075
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.925 0.075
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.925 0.075
E16.4 Abnormal secretion of gastrin
0.000 0.925 0.075
E16.3 Increased secretion of glucagon
0.000 0.925 0.075
E79 Disorders of purine and pyrimidine metabolism
0.000 0.926 0.074
E14.7 With multiple complications
0.000 0.926 0.074
E14.2 Withrenal complications
0.000 0.926 0.074
E14.0 With coma
0.000 0.926 0.074
E85.9 Amyloidosis, unspecified
0.000 0.929 0.071
E14.6 With other specified complications
0.000 0.931 0.068
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.932 0.068
E45 Retarded development following protein-energy malnutrition
0.000 0.932 0.068
E43 Unspecified severe protein-energy malnutrition
0.000 0.932 0.068
E42 Marasmic kwashiorkor
0.000 0.932 0.068
E41 Nutritional marasmus
0.000 0.932 0.068
E40 Kwashiorkor
0.000 0.932 0.068
E14.4 With neurological complications
0.000 0.932 0.067
E14.1 With ketoacidosis
0.000 0.933 0.067
E85.8 Other amyloidosis
0.000 0.936 0.063
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.936 0.063
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.936 0.063
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.936 0.063
E65-E68 Obesity and other hyperalimentation
0.000 0.937 0.063
E73 Lactose intolerance
0.000 0.937 0.063
E85.4 Organ-limited amyloidosis
0.000 0.938 0.062
E11.3 With ophthalmic complications
0.000 0.938 0.062
E85.3 Secondary systemic amyloidosis
0.000 0.939 0.061
E74 Other disorders of carbohydrate metabolism
0.000 0.940 0.060
E71.3 Disorders of fatty-acid metabolism
0.000 0.940 0.060
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.940 0.060
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.940 0.060
E71.0 Maple-syrup-urine disease
0.000 0.940 0.060
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.940 0.060
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.940 0.060
E72.5 Disorders of glycine metabolism
0.000 0.940 0.060
E72.4 Disorders of ornithine metabolism
0.000 0.940 0.060
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.940 0.060
E72.2 Disorders of urea cycle metabolism
0.000 0.940 0.060
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.940 0.060
E72.0 Disorders of amino-acid transport
0.000 0.940 0.060
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.940 0.060
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.940 0.060
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.940 0.060
E76.2 Other mucopolysaccharidoses
0.000 0.940 0.060
E76.1 Mucopolysaccharidosis, type II
0.000 0.940 0.060
E76.0 Mucopolysaccharidosis, type I
0.000 0.940 0.060
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.940 0.060
E77.8 Other disorders of glycoprotein metabolism
0.000 0.940 0.060
E77.1 Defects in glycoprotein degradation
0.000 0.940 0.060
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.940 0.060
E84.9 Cystic fibrosis, unspecified
0.000 0.940 0.060
E84.8 Cystic fibrosis with other manifestations
0.000 0.940 0.060
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.940 0.060
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.940 0.060
E80.4 Gilbert's syndrome
0.000 0.941 0.059
E75.6 Lipid storage disorder, unspecified
0.000 0.942 0.058
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.942 0.058
E75.3 Sphingolipidosis, unspecified
0.000 0.942 0.058
E75.2 Other sphingolipidosis
0.000 0.942 0.058
E75.1 Other gangliosidosis
0.000 0.942 0.058
E75.0 GM2 gangliosidosis
0.000 0.942 0.058
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.943 0.057
E80.5 Crigler-Najjar syndrome
0.000 0.943 0.057
E80.3 Defects of catalase and peroxydase
0.000 0.943 0.057
E80.1 Porphyria cutanea tarda
0.000 0.943 0.057
E80.0 Hereditary erythropoietic porphyria
0.000 0.943 0.057
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.944 0.056
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.944 0.056
E70.2 Disorders of tyrosine metabolism
0.000 0.944 0.056
E70.1 Other hyperphenylalaninaemias
0.000 0.944 0.056
E70.0 Classical phenylketonuria
0.000 0.944 0.056
E80.6 Other disorders of bilirubin metabolism
0.000 0.944 0.056
E83.4 Disorders of magnesium metabolism
0.000 0.945 0.055
E16.1 Other hypoglycaemia
0.000 0.945 0.055
E75.5 Other lipid storage disorders
0.000 0.945 0.055
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.947 0.053
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.947 0.053
E79.1 Lesch-Nyhan syndrome
0.000 0.947 0.053
E80.2 Other porphyria
0.000 0.947 0.053
E14.8 With unspecified complications
0.000 0.947 0.053
E65 Localised adiposity
0.000 0.949 0.051
E70.3 Albinism
0.000 0.949 0.050
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.949 0.051
E44.1 Mild protein-energy malnutrition
0.000 0.951 0.049
E44.0 Moderate protein-energy malnutrition
0.000 0.951 0.049
E67 Other hyperalimentation
0.000 0.954 0.046
E68 Sequelae of hyperalimentation
0.000 0.954 0.046
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.954 0.046
E73.8 Other lactose intolerance
0.000 0.954 0.045
E73.1 Secondary lactase deficiency
0.000 0.954 0.045
E73.0 Congenital lactase deficiency
0.000 0.954 0.045
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.954 0.046
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.956 0.044
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.957 0.043
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.957 0.043
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.957 0.043
E74.2 Disorders of galactose metabolism
0.000 0.957 0.043
E74.1 Disorders of fructose metabolism
0.000 0.957 0.043
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.958 0.042
E50-E64 Other nutritional deficiencies
0.000 0.958 0.041
E74.0 Glycogen storage disease
0.000 0.961 0.039
E89.4 Postprocedural ovarian failure
0.000 0.962 0.038
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.962 0.038
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.963 0.036
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.963 0.036
E89.5 Postprocedural testicular hypofunction
0.000 0.963 0.036
E89.1 Postprocedural hypoinsulinaemia
0.000 0.963 0.036
E87.5 Hyperkalaemia
0.000 0.964 0.036
E87.0 Hyperosmolality and hypernatraemia
0.000 0.964 0.036
E89.2 Postprocedural hypoparathyroidism
0.000 0.965 0.035
E78.2 Mixed hyperlipidaemia
0.000 0.965 0.035
E87.3 Alkalosis
0.000 0.965 0.035
E78.4 Other hyperlipidaemia
0.000 0.966 0.034
E67.8 Other specified hyperalimentation
0.000 0.967 0.033
E67.3 Hypervitaminosis D
0.000 0.967 0.033
E67.2 Megavitamin-B6 syndrome
0.000 0.967 0.033
E67.1 Hypercarotenaemia
0.000 0.967 0.033
E67.0 Hypervitaminosis A
0.000 0.967 0.033
E78.3 Hyperchylomicronaemia
0.000 0.967 0.033
E87.7 Fluid overload
0.000 0.968 0.032
E78.6 Lipoprotein deficiency
0.000 0.968 0.031
E78.1 Pure hyperglyceridaemia
0.000 0.969 0.031
E87.4 Mixed disorder of acid-base balance
0.000 0.969 0.030
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.970 0.030
E63 Other nutritional deficiencies
0.000 0.970 0.030
E50 Vitamin A deficiency
0.000 0.970 0.030
E60 Dietary zinc deficiency
0.000 0.970 0.030
E59 Dietary selenium deficiency
0.000 0.970 0.030
E54 Ascorbic acid deficiency
0.000 0.970 0.030
E52 Niacin deficiency [pellagra]
0.000 0.970 0.030
E58 Dietary calcium deficiency
0.000 0.970 0.029
E56 Other vitamin deficiencies
0.000 0.971 0.029
E00-E07 Disorders of thyroid gland
0.000 0.971 0.029
E53 Deficiency of other B group vitamins
0.000 0.971 0.029
E51 Thiamine deficiency
0.000 0.971 0.028
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.972 0.028
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.972 0.028
R31 Unspecified haematuria
0.028 0.972 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.974 0.026
E73.9 Lactose intolerance, unspecified
0.001 0.974 0.025
E55 Vitamin D deficiency
0.000 0.976 0.024
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.976 0.024
E87.2 Acidosis
0.000 0.977 0.023
E53.9 Vitamin B deficiency, unspecified
0.000 0.978 0.022
E50.9 Vitamin A deficiency, unspecified
0.000 0.978 0.021
E50.8 Other manifestations of vitamin A deficiency
0.000 0.978 0.021
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.978 0.021
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.978 0.021
E50.5 Vitamin A deficiency with night blindness
0.000 0.978 0.021
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.978 0.021
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.978 0.021
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.978 0.021
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.978 0.021
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.978 0.021
E63.9 Nutritional deficiency, unspecified
0.000 0.978 0.021
E63.8 Other specified nutritional deficiencies
0.000 0.978 0.021
E63.1 Imbalance of constituents of food intake
0.000 0.978 0.021
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.978 0.021
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.978 0.021
E64.8 Sequelae of other nutritional deficiencies
0.000 0.978 0.021
E64.3 Sequelae of rickets
0.000 0.978 0.021
E64.2 Sequelae of vitamin C deficiency
0.000 0.978 0.021
E64.1 Sequelae of vitamin A deficiency
0.000 0.978 0.021
E64.0 Sequelae of protein-energy malnutrition
0.000 0.978 0.021
E83.5 Disorders of calcium metabolism
0.000 0.979 0.021
E56.9 Vitamin deficiency, unspecified
0.000 0.979 0.021
E56.8 Deficiency of other vitamins
0.000 0.979 0.021
E56.0 Deficiency of vitamin E
0.000 0.979 0.021
E07 Other disorders of thyroid
0.000 0.979 0.021
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.979 0.021
E00 Congenital iodine-deficiency syndrome
0.000 0.979 0.021
E53.1 Pyridoxine deficiency
0.000 0.979 0.021
E53.0 Riboflavin deficiency
0.000 0.979 0.021
E51.9 Thiamine deficiency, unspecified
0.000 0.979 0.020
E51.8 Other manifestations of thiamine deficiency
0.000 0.979 0.020
E51.1 Beriberi
0.000 0.979 0.020
E56.1 Deficiency of vitamin K
0.000 0.980 0.020
E06 Thyroiditis
0.000 0.980 0.020
G31.8 Other specified degenerative diseases of nervous system
0.000 0.980 0.020
E89.3 Postprocedural hypopituitarism
0.000 0.981 0.019
E51.2 Wernicke's encephalopathy
0.000 0.981 0.019
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.981 0.019
E04 Other non-toxic goitre
0.000 0.981 0.019
E20-E35 Disorders of other endocrine glands
0.000 0.982 0.018
E14.9 Without complications
0.000 0.982 0.018
E55.0 Rickets, active
0.000 0.982 0.017
E53.8 Deficiency of other specified B group vitamins
0.000 0.983 0.017
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.983 0.017
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.983 0.017
G31.0 Circumscribed brain atrophy
0.000 0.983 0.017
G30 Alzheimer's disease
0.000 0.983 0.017
M25.57 Pain in joint (Ankle and foot)
0.000 0.983 0.017
G30-G32 Other degenerative diseases of the nervous system
0.000 0.984 0.016
E04.9 Non-toxic goitre, unspecified
0.000 0.984 0.016
E07.9 Disorder of thyroid, unspecified
0.000 0.984 0.016
G30.9 Alzheimer's disease, unspecified
0.000 0.984 0.016
E61 Deficiency of other nutrient elements
0.001 0.984 0.015
G30.0 Alzheimer's disease with early onset
0.000 0.984 0.015
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.985 0.015
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.985 0.015
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.985 0.015
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.985 0.015
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.985 0.015
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.985 0.015
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.985 0.015
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.985 0.015
E07.1 Dyshormogenetic goitre
0.000 0.985 0.015
E07.0 Hypersecretion of calcitonin
0.000 0.985 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.985 0.015
K90-K93 Other diseases of the digestive system
0.000 0.985 0.015
M25.5 Pain in joint
0.000 0.985 0.015
E07.8 Other specified disorders of thyroid
0.000 0.985 0.014
E06.5 Other chronic thyroiditis
0.000 0.985 0.014
E06.4 Drug-induced thyroiditis
0.000 0.985 0.014
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.985 0.014
E06.1 Subacute thyroiditis
0.000 0.985 0.014
E06.0 Acute thyroiditis
0.000 0.985 0.014
E20 Hypoparathyroidism
0.000 0.986 0.014
E86 Volume depletion
0.000 0.986 0.014
E04.0 Non-toxic diffuse goitre
0.000 0.986 0.014
E78.8 Other disorders of lipoprotein metabolism
0.001 0.986 0.014
E06.3 Autoimmune thyroiditis
0.000 0.986 0.014
E26 Hyperaldosteronism
0.000 0.986 0.014
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.986 0.014
E27 Other disorders of adrenal gland
0.000 0.986 0.014
E06.9 Thyroiditis, unspecified
0.000 0.986 0.014
E04.8 Other specified non-toxic goitre
0.000 0.986 0.013
E29 Testicular dysfunction
0.000 0.986 0.013
G30.8 Other Alzheimer's disease
0.000 0.986 0.013
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.987 0.013
E32 Diseases of thymus
0.000 0.987 0.013
E31 Polyglandular dysfunction
0.000 0.987 0.013
E30 Disorders of puberty, not elsewhere classified
0.000 0.987 0.013
E25 Adrenogenital disorders
0.000 0.987 0.013
E03 Other hypothyroidism
0.000 0.987 0.013
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.987 0.013
G30.1 Alzheimer's disease with late onset
0.000 0.988 0.012
M25.58 Pain in joint (Other)
0.000 0.988 0.012
E24 Cushing's syndrome
0.000 0.988 0.012
M25.52 Pain in joint (Upper arm)
0.000 0.988 0.012
E20.9 Hypoparathyroidism, unspecified
0.000 0.988 0.012
E55.9 Vitamin D deficiency, unspecified
0.000 0.988 0.012
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.988 0.012
E61.9 Deficiency of nutrient element, unspecified
0.001 0.988 0.011
E61.8 Deficiency of other specified nutrient elements
0.001 0.988 0.011
E61.7 Deficiency of multiple nutrient elements
0.001 0.988 0.011
E61.6 Vanadium deficiency
0.001 0.988 0.011
E61.5 Molybdenum deficiency
0.001 0.988 0.011
E61.4 Chromium deficiency
0.001 0.988 0.011
E61.3 Manganese deficiency
0.001 0.988 0.011
E61.0 Copper deficiency
0.001 0.988 0.011
M25.51 Pain in joint (Shoulder region)
0.000 0.989 0.011
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.989 0.011
M25.54 Pain in joint (Hand)
0.000 0.989 0.011
E26.0 Primary hyperaldosteronism
0.000 0.989 0.011
E34 Other endocrine disorders
0.000 0.989 0.011
E23 Hypofunction and other disorders of pituitary gland
0.000 0.989 0.011
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.989 0.011
E20.8 Other hypoparathyroidism
0.000 0.989 0.010
E20.1 Pseudohypoparathyroidism
0.000 0.989 0.010
E20.0 Idiopathic hypoparathyroidism
0.000 0.989 0.010
E24.2 Drug-induced Cushing's syndrome
0.000 0.989 0.011
E03.8 Other specified hypothyroidism
0.000 0.990 0.010
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.990 0.010
E28 Ovarian dysfunction
0.000 0.990 0.010
E05.8 Other thyrotoxicosis
0.000 0.990 0.010
E29.1 Testicular hypofunction
0.000 0.990 0.010
E26.9 Hyperaldosteronism, unspecified
0.000 0.990 0.010
E26.8 Other hyperaldosteronism
0.000 0.990 0.010
E26.1 Secondary hyperaldosteronism
0.000 0.990 0.010
E27.5 Adrenomedullary hyperfunction
0.000 0.990 0.010
E27.0 Other adrenocortical overactivity
0.000 0.990 0.010
G44.2 Tension-type headache
0.010 0.990 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.990 0.010
E29.9 Testicular dysfunction, unspecified
0.000 0.990 0.010
E29.8 Other testicular dysfunction
0.000 0.990 0.010
E29.0 Testicular hyperfunction
0.000 0.990 0.010
M25.53 Pain in joint (Forearm)
0.000 0.990 0.010
E23.2 Diabetes insipidus
0.000 0.990 0.010
E25.9 Adrenogenital disorder, unspecified
0.000 0.990 0.010
E25.8 Other adrenogenital disorders
0.000 0.990 0.010
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.990 0.010
E30.9 Disorder of puberty, unspecified
0.000 0.990 0.010
E30.8 Other disorders of puberty
0.000 0.990 0.010
E30.1 Precocious puberty
0.000 0.990 0.010
E30.0 Delayed puberty
0.000 0.990 0.010
E31.9 Polyglandular dysfunction, unspecified
0.000 0.990 0.010
E31.8 Other polyglandular dysfunction
0.000 0.990 0.010
E31.1 Polyglandular hyperfunction
0.000 0.990 0.010
E31.0 Autoimmune polyglandular failure
0.000 0.990 0.010
E32.9 Disease of thymus, unspecified
0.000 0.990 0.010
E32.8 Other diseases of thymus
0.000 0.990 0.010
E32.1 Abscess of thymus
0.000 0.990 0.010
E32.0 Persistent hyperplasia of thymus
0.000 0.990 0.010
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.990 0.010
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.990 0.010
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.990 0.010
E03.5 Myxoedema coma
0.000 0.990 0.010
E03.4 Atrophy of thyroid (acquired)
0.000 0.990 0.010
E03.3 Postinfectious hypothyroidism
0.000 0.990 0.010
E03.1 Congenital hypothyroidism without goitre
0.000 0.990 0.010
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.990 0.010
E05.5 Thyroid crisis or storm
0.000 0.990 0.009
E05.4 Thyrotoxicosis factitia
0.000 0.990 0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.990 0.009
E66 Obesity
0.000 0.991 0.009
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.991 0.009
E04.1 Non-toxic single thyroid nodule
0.000 0.991 0.009
E61.2 Magnesium deficiency
0.001 0.991 0.008
E24.8 Other Cushing's syndrome
0.000 0.991 0.009
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.991 0.009
E24.3 Ectopic ACTH syndrome
0.000 0.991 0.009
E24.1 Nelson's syndrome
0.000 0.991 0.009
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.991 0.009
E04.2 Non-toxic multinodular goitre
0.000 0.991 0.009
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.991 0.008
E27.2 Addisonian crisis
0.000 0.992 0.008
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.992 0.008
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.992 0.008
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.992 0.008
K93.1 Megacolon in Chagas' disease
0.000 0.992 0.008
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.992 0.008
E24.0 Pituitary-dependent Cushing's disease
0.000 0.992 0.008
E87.6 Hypokalaemia
0.000 0.992 0.008
E34.5 Androgen resistance syndrome
0.000 0.992 0.008
E34.4 Constitutional tall stature
0.000 0.992 0.008
E34.3 Short stature, not elsewhere classified
0.000 0.992 0.008
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.992 0.008
E34.1 Other hypersecretion of intestinal hormones
0.000 0.992 0.008
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.992 0.008
E23.1 Drug-induced hypopituitarism
0.000 0.992 0.008
E34.0 Carcinoid syndrome
0.000 0.992 0.008
E28.9 Ovarian dysfunction, unspecified
0.000 0.992 0.008
E28.8 Other ovarian dysfunction
0.000 0.992 0.008
E28.1 Androgen excess
0.000 0.992 0.008
E28.0 Oestrogen excess
0.000 0.992 0.008
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.992 0.008
E28.2 Polycystic ovarian syndrome
0.000 0.992 0.008
E23.7 Disorder of pituitary gland, unspecified
0.000 0.992 0.008
E34.9 Endocrine disorder, unspecified
0.000 0.993 0.007
E66.1 Drug-induced obesity
0.000 0.993 0.007
M25.59 Pain in joint (Site unspecified)
0.000 0.993 0.007
E34.8 Other specified endocrine disorders
0.000 0.993 0.007
E27.8 Other specified disorders of adrenal gland
0.000 0.993 0.007
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.993 0.007
E23.6 Other disorders of pituitary gland
0.000 0.993 0.006
K02.9 Dental caries, unspecified
0.000 0.994 0.006
E24.9 Cushing's syndrome, unspecified
0.000 0.994 0.006
E66.0 Obesity due to excess calories
0.000 0.994 0.006
K02.8 Other dental caries
0.000 0.994 0.006
G44 Other headache syndromes
0.006 0.994 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.994 0.005
K02 Dental caries
0.000 0.995 0.005
K56.4 Other impaction of intestine
0.005 0.995 0.000
E28.3 Primary ovarian failure
0.001 0.995 0.004
G44.8 Other specified headache syndromes
0.005 0.995 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.995 0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.995 0.005
G54.9 Nerve root and plexus disorder, unspecified
0.005 0.995 0.000
E11.9 Without complications
0.000 0.995 0.005
G82.5 Tetraplegia, unspecified
0.000 0.995 0.005
E22 Hyperfunction of pituitary gland
0.000 0.995 0.004
G82.4 Spastic tetraplegia
0.000 0.995 0.005
G82 Paraplegia and tetraplegia
0.000 0.996 0.004
E61.1 Iron deficiency
0.002 0.996 0.003
K22.8 Other specified diseases of oesophagus
0.004 0.996 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.996 0.004
G44.1 Vascular headache, not elsewhere classified
0.004 0.996 0.000
K02.1 Caries of dentin
0.000 0.996 0.004
G44.0 Cluster headache syndrome
0.004 0.996 0.000
G82.1 Spastic paraplegia
0.000 0.996 0.004
G44.4 Drug-induced headache, not elsewhere classified
0.004 0.996 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.996 0.004
M25.50 Pain in joint (Multiple sites)
0.000 0.996 0.004
K02.5 Caries with pulp exposure
0.000 0.996 0.004
K02.4 Odontoclasia
0.000 0.996 0.004
K02.3 Arrested dental caries
0.000 0.996 0.004
K02.2 Caries of cementum
0.000 0.996 0.004
K02.0 Caries limited to enamel
0.000 0.996 0.004
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.004 0.996 0.000
K56.2 Volvulus
0.004 0.996 0.000
G71.1 Myotonic disorders
0.000 0.996 0.004
G44.3 Chronic posttraumatic headache
0.004 0.996 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.996 0.004
M41.9 Scoliosis, unspecified
0.004 0.996 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.004 0.996 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.996 0.004
E21.2 Other hyperparathyroidism
0.000 0.996 0.004
K56 Paralytic ileus and intestinal obstruction without hernia
0.004 0.996 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.000 0.996 0.004
E22.8 Other hyperfunction of pituitary gland
0.000 0.996 0.003
M41.94 Scoliosis, unspecified (Thoracic region)
0.004 0.996 0.000
N04.9 Unspecified
0.000 0.996 0.004
M79.10 Myalgia (Multiple sites)
0.004 0.996 0.000
G82.3 Flaccid tetraplegia
0.000 0.997 0.003
G82.0 Flaccid paraplegia
0.000 0.997 0.003
K56.5 Intestinal adhesions [bands] with obstruction
0.003 0.997 0.000
G71 Primary disorders of muscles
0.000 0.997 0.003
M24.54 Contracture of joint (Hand)
0.003 0.997 0.000
M67.8 Other specified disorders of synovium and tendon
0.000 0.997 0.003
M41.96 Scoliosis, unspecified (Lumbar region)
0.003 0.997 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.003 0.997 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.997 0.003
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.000 0.997 0.003
M96.5 Postradiation scoliosis
0.000 0.997 0.003
M96.4 Postsurgical lordosis
0.000 0.997 0.003
M96.3 Postlaminectomy kyphosis
0.000 0.997 0.003
M96.2 Postradiation kyphosis
0.000 0.997 0.003
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.997 0.003
C71.2 Temporal lobe
0.003 0.997 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.003 0.997 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.997 0.003
E23.0 Hypopituitarism
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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