TreeWAS – Variant ID: rs2153157

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.000	0.032	0.968
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.285	0.715
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.418	0.582
E21.4 Other specified disorders of parathyroid gland	0.000	0.437	0.563
E21.3 Hyperparathyroidism, unspecified	0.000	0.441	0.559
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.443	0.557
E21.2 Other hyperparathyroidism	0.000	0.500	0.500
E20-E35 Disorders of other endocrine glands	0.000	0.857	0.143
E22 Hyperfunction of pituitary gland	0.000	0.872	0.128
E22.0 Acromegaly and pituitary gigantism	0.000	0.885	0.115
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.892	0.108
E29 Testicular dysfunction	0.000	0.896	0.104
E25 Adrenogenital disorders	0.000	0.896	0.104
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.897	0.103
E32 Diseases of thymus	0.000	0.897	0.103
E31 Polyglandular dysfunction	0.000	0.897	0.103
E30 Disorders of puberty, not elsewhere classified	0.000	0.897	0.103
E24 Cushing's syndrome	0.000	0.899	0.101
E26 Hyperaldosteronism	0.000	0.899	0.101
E20 Hypoparathyroidism	0.000	0.906	0.093
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.908	0.092
E22.8 Other hyperfunction of pituitary gland	0.000	0.908	0.092
E23 Hypofunction and other disorders of pituitary gland	0.000	0.910	0.090
E34 Other endocrine disorders	0.000	0.911	0.089
E24.2 Drug-induced Cushing's syndrome	0.000	0.915	0.085
E26.9 Hyperaldosteronism, unspecified	0.000	0.918	0.082
E29.1 Testicular hypofunction	0.000	0.921	0.079
E23.0 Hypopituitarism	0.000	0.923	0.077
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.924	0.076
E22.1 Hyperprolactinaemia	0.000	0.925	0.075
E29.8 Other testicular dysfunction	0.000	0.925	0.075
E29.0 Testicular hyperfunction	0.000	0.925	0.075
E25.9 Adrenogenital disorder, unspecified	0.000	0.925	0.075
E25.8 Other adrenogenital disorders	0.000	0.925	0.075
E30.9 Disorder of puberty, unspecified	0.000	0.926	0.074
E30.8 Other disorders of puberty	0.000	0.926	0.074
E30.1 Precocious puberty	0.000	0.926	0.074
E30.0 Delayed puberty	0.000	0.926	0.074
E31.9 Polyglandular dysfunction, unspecified	0.000	0.926	0.074
E31.8 Other polyglandular dysfunction	0.000	0.926	0.074
E31.1 Polyglandular hyperfunction	0.000	0.926	0.074
E31.0 Autoimmune polyglandular failure	0.000	0.926	0.074
E32.9 Disease of thymus, unspecified	0.000	0.926	0.074
E32.8 Other diseases of thymus	0.000	0.926	0.074
E32.1 Abscess of thymus	0.000	0.926	0.074
E32.0 Persistent hyperplasia of thymus	0.000	0.926	0.074
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.926	0.074
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.926	0.074
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.926	0.074
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.927	0.073
E24.3 Ectopic ACTH syndrome	0.000	0.927	0.073
E24.1 Nelson's syndrome	0.000	0.927	0.073
E26.8 Other hyperaldosteronism	0.000	0.927	0.072
E26.1 Secondary hyperaldosteronism	0.000	0.927	0.072
E28 Ovarian dysfunction	0.000	0.929	0.071
E29.9 Testicular dysfunction, unspecified	0.000	0.929	0.071
E24.8 Other Cushing's syndrome	0.000	0.931	0.069
E20.8 Other hypoparathyroidism	0.000	0.933	0.067
E20.1 Pseudohypoparathyroidism	0.000	0.933	0.067
E20.0 Idiopathic hypoparathyroidism	0.000	0.933	0.067
E34.8 Other specified endocrine disorders	0.000	0.933	0.067
E24.0 Pituitary-dependent Cushing's disease	0.000	0.933	0.067
E23.7 Disorder of pituitary gland, unspecified	0.000	0.935	0.065
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.935	0.064
E23.1 Drug-induced hypopituitarism	0.000	0.935	0.064
E34.9 Endocrine disorder, unspecified	0.000	0.936	0.064
E34.5 Androgen resistance syndrome	0.000	0.936	0.064
E34.4 Constitutional tall stature	0.000	0.936	0.064
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.936	0.064
E34.1 Other hypersecretion of intestinal hormones	0.000	0.936	0.064
E27 Other disorders of adrenal gland	0.000	0.936	0.063
E34.3 Short stature, not elsewhere classified	0.000	0.937	0.063
E24.9 Cushing's syndrome, unspecified	0.000	0.937	0.062
E20.9 Hypoparathyroidism, unspecified	0.000	0.942	0.058
E27.8 Other specified disorders of adrenal gland	0.000	0.943	0.057
E26.0 Primary hyperaldosteronism	0.000	0.945	0.055
E28.9 Ovarian dysfunction, unspecified	0.000	0.949	0.051
E28.8 Other ovarian dysfunction	0.000	0.949	0.051
E28.1 Androgen excess	0.000	0.949	0.051
E28.0 Oestrogen excess	0.000	0.949	0.051
E27.9 Disorder of adrenal gland, unspecified	0.000	0.950	0.050
E23.2 Diabetes insipidus	0.000	0.953	0.046
E34.0 Carcinoid syndrome	0.000	0.954	0.046
E27.5 Adrenomedullary hyperfunction	0.000	0.954	0.046
E27.0 Other adrenocortical overactivity	0.000	0.954	0.046
D35.1 Parathyroid gland	0.000	0.956	0.044
E23.6 Other disorders of pituitary gland	0.000	0.957	0.043
E28.3 Primary ovarian failure	0.000	0.960	0.040
E28.2 Polycystic ovarian syndrome	0.000	0.962	0.038
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.964	0.036
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.964	0.036
E27.2 Addisonian crisis	0.000	0.968	0.032
E55.9 Vitamin D deficiency, unspecified	0.000	0.972	0.028
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.978	0.022
K74.3 Primary biliary cirrhosis	0.018	0.982	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.982	0.017
E55 Vitamin D deficiency	0.000	0.983	0.017
K74 Fibrosis and cirrhosis of liver	0.016	0.984	0.000
K74.6 Other and unspecified cirrhosis of liver	0.015	0.985	0.000
K74.5 Biliary cirrhosis, unspecified	0.015	0.985	0.000
E55.0 Rickets, active	0.000	0.988	0.012
K74.4 Secondary biliary cirrhosis	0.012	0.988	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.012	0.988	0.000
K74.1 Hepatic sclerosis	0.011	0.988	0.000
K74.0 Hepatic fibrosis	0.009	0.990	0.000
M22.4 Chondromalacia patellae	0.009	0.991	0.000
H43.1 Vitreous haemorrhage	0.000	0.991	0.009
H43 Disorders of vitreous body	0.000	0.991	0.009
H43.2 Crystalline deposits in vitreous body	0.000	0.992	0.008
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.992	0.008
C18.2 Ascending colon	0.000	0.993	0.007
H43.8 Other disorders of vitreous body	0.000	0.993	0.007
F41 Other anxiety disorders	0.000	0.993	0.007
H43.9 Disorder of vitreous body, unspecified	0.000	0.993	0.007
O34.2 Maternal care due to uterine scar from previous surgery	0.007	0.993	0.000
O34.1 Maternal care for tumour of corpus uteri	0.007	0.993	0.000
O46.9 Antepartum haemorrhage, unspecified	0.007	0.993	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.993	0.007
O34 Maternal care for known or suspected abnormality of pelvic organs	0.007	0.993	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.993	0.007
F41.9 Anxiety disorder, unspecified	0.000	0.993	0.007
H43.0 Vitreous prolapse	0.000	0.993	0.006
F41.8 Other specified anxiety disorders	0.000	0.994	0.006
O46 Antepartum haemorrhage, not elsewhere classified	0.006	0.994	0.000
H43.3 Other vitreous opacities	0.000	0.994	0.006
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.994	0.006
O34.0 Maternal care for congenital malformation of uterus	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
M22 Disorders of patella	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.000	0.994	0.006
O34.4 Maternal care for other abnormalities of cervix	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.000	0.994	0.006
O34.3 Maternal care for cervical incompetence	0.006	0.994	0.000
O46.8 Other antepartum haemorrhage	0.006	0.994	0.000
M22.8 Other disorders of patella	0.006	0.994	0.000
E51 Thiamine deficiency	0.000	0.994	0.005
O34.5 Maternal care for other abnormalities of gravid uterus	0.005	0.995	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.995	0.005
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
D13.1 Stomach	0.000	0.995	0.005
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.005	0.995	0.000
O34.6 Maternal care for abnormality of vagina	0.005	0.995	0.000
O33.9 Maternal care for disproportion, unspecified	0.005	0.995	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.005	0.995	0.000
O33 Maternal care for known or suspected disproportion	0.005	0.995	0.000
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
H44 Disorders of globe	0.000	0.995	0.005
F41.1 Generalised anxiety disorder	0.000	0.995	0.005
C26.0 Intestinal tract, part unspecified	0.000	0.995	0.005
E61 Deficiency of other nutrient elements	0.000	0.995	0.005
O40 Polyhydramnios	0.005	0.995	0.000
F41.3 Other mixed anxiety disorders	0.000	0.995	0.005
M22.3 Other derangements of patella	0.005	0.995	0.000
H44.5 Degenerated conditions of globe	0.000	0.995	0.005
O32.1 Maternal care for breech presentation	0.000	0.995	0.005
O46.0 Antepartum haemorrhage with coagulation defect	0.005	0.995	0.000
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
O47 False labour	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.995	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.995	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.995	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.995	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.995	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.995	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.995	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.995	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.995	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.995	0.004
E64.3 Sequelae of rickets	0.000	0.995	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.995	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.995	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.995	0.004
M22.1 Recurrent subluxation of patella	0.004	0.995	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.995	0.005
M62.8 Other specified disorders of muscle	0.005	0.995	0.000
R25.1 Tremor, unspecified	0.000	0.995	0.005
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.004
E56.9 Vitamin deficiency, unspecified	0.000	0.996	0.004
E56.8 Deficiency of other vitamins	0.000	0.996	0.004
E56.0 Deficiency of vitamin E	0.000	0.996	0.004
O31 Complications specific to multiple gestation	0.004	0.996	0.000
O43 Placental disorders	0.004	0.996	0.000
H44.2 Degenerative myopia	0.000	0.996	0.004
O44 Placenta praevia	0.004	0.996	0.000
E61.2 Magnesium deficiency	0.000	0.996	0.004
H44.9 Disorder of globe, unspecified	0.000	0.996	0.004
M22.2 Patellofemoral disorders	0.004	0.996	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.004	0.996	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.996	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.004
E51.9 Thiamine deficiency, unspecified	0.000	0.996	0.004
E51.8 Other manifestations of thiamine deficiency	0.000	0.996	0.004
E51.1 Beriberi	0.000	0.996	0.004
O34.8 Maternal care for other abnormalities of pelvic organs	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.000	0.996	0.004
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.004	0.996	0.000
M62.84 Other specified disorders of muscle (Hand)	0.004	0.996	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.004	0.996	0.000
H44.4 Hypotony of eye	0.000	0.996	0.004
O34.7 Maternal care for abnormality of vulva and perineum	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.996	0.004
H44.1 Other endophthalmitis	0.000	0.996	0.004
O33.5 Maternal care for disproportion due to unusually large foetus	0.004	0.996	0.000
M22.0 Recurrent dislocation of patella	0.004	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
H44.8 Other disorders of globe	0.000	0.996	0.004
O44.1 Placenta praevia with haemorrhage	0.004	0.996	0.000
O33.8 Maternal care for disproportion of other origin	0.004	0.996	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.004	0.996	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.004	0.996	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.004	0.996	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.004	0.996	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.004	0.996	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.004	0.996	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.004	0.996	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.996	0.004
H44.3 Other degenerative disorders of globe	0.000	0.996	0.004
E61.9 Deficiency of nutrient element, unspecified	0.000	0.996	0.004
E61.8 Deficiency of other specified nutrient elements	0.000	0.996	0.004
E61.7 Deficiency of multiple nutrient elements	0.000	0.996	0.004
E61.6 Vanadium deficiency	0.000	0.996	0.004
E61.5 Molybdenum deficiency	0.000	0.996	0.004
E61.4 Chromium deficiency	0.000	0.996	0.004
E61.3 Manganese deficiency	0.000	0.996	0.004
E61.0 Copper deficiency	0.000	0.996	0.004
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.004	0.996	0.000
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
C16.9 Stomach, unspecified	0.004	0.996	0.000
O43.1 Malformation of placenta	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
O31.8 Other complications specific to multiple gestation	0.004	0.996	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.004	0.996	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.000	0.996	0.003
O41.0 Oligohydramnios	0.004	0.996	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.996	0.000
O43.0 Placental transfusion syndromes	0.004	0.996	0.000
O47.9 False labour, unspecified	0.004	0.996	0.000
E40-E46 Malnutrition	0.000	0.996	0.003
M22.10 Recurrent subluxation of patella, unspecified knee	0.003	0.996	0.000
D35.9 Endocrine gland, unspecified	0.000	0.996	0.003
D35.8 Pluriglandular involvement	0.000	0.996	0.003
D35.7 Other specified endocrine glands	0.000	0.996	0.003
D35.6 Aortic body and other paraganglia	0.000	0.996	0.003
D35.5 Carotid body	0.000	0.996	0.003
D35.4 Pineal gland	0.000	0.996	0.003
D35.3 Craniopharyngeal duct	0.000	0.996	0.003
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.996	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.003	0.997	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.997	0.003
O43.9 Placental disorder, unspecified	0.003	0.997	0.000
M62.88 Other specified disorders of muscle (Other)	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
O43.2 Morbidly adherent placenta	0.003	0.997	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.997	0.003
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.003
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.997	0.003
O20.0 Threatened abortion	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
M62 Other disorders of muscle	0.003	0.997	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.997	0.003
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.997	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
O30 Multiple gestation	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
O43.8 Other placental disorders	0.003	0.997	0.000
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
C16 Malignant neoplasm of stomach	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.003	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
O42 Premature rupture of membranes	0.003	0.997	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.997	0.003
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
M62.6 Muscle strain	0.003	0.997	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.003	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.997	0.003
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.997	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.997	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.997	0.003
E42 Marasmic kwashiorkor	0.000	0.997	0.003
E41 Nutritional marasmus	0.000	0.997	0.003
E40 Kwashiorkor	0.000	0.997	0.003
C16.1 Fundus of stomach	0.003	0.997	0.000
M62.2 Ischaemic infarction of muscle	0.003	0.997	0.000
C16.2 Body of stomach	0.003	0.997	0.000
C16.0 Cardia	0.003	0.997	0.000
M62.9 Disorder of muscle, unspecified	0.003	0.997	0.000
O30.1 Triplet pregnancy	0.003	0.997	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.003	0.997	0.000
D16.4 Bones of skull and face	0.000	0.997	0.003
T83.2 Mechanical complication of graft of urinary organ	0.000	0.997	0.003
M62.0 Diastasis of muscle	0.002	0.997	0.000
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
M62.4 Contracture of muscle	0.002	0.997	0.000
M62.3 Immobility syndrome (paraplegic)	0.002	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
M62.68 Muscle strain (Other)	0.002	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.000	0.997	0.002
C26.1 Spleen	0.000	0.997	0.002
F40.2 Specific (isolated) phobias	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.002	0.997	0.000
O30.8 Other multiple gestation	0.002	0.997	0.000
O30.2 Quadruplet pregnancy	0.002	0.997	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.002
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.002	0.997	0.000
M62.26 Ischaemic infarction of muscle (Lower leg)	0.002	0.997	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.002	0.997	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
C16.4 Pylorus	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
M62.69 Muscle strain (Site unspecified)	0.002	0.998	0.000
M62.67 Muscle strain (Ankle and foot)	0.002	0.998	0.000
M62.64 Muscle strain (Hand)	0.002	0.998	0.000
M62.63 Muscle strain (Forearm)	0.002	0.998	0.000
M62.62 Muscle strain (Upper arm)	0.002	0.998	0.000
M62.61 Muscle strain (Shoulder region)	0.002	0.998	0.000
M62.60 Muscle strain (Multiple sites)	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
M62.65 Muscle strain (Pelvic region and thigh)	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.998	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.998	0.002
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
C16.8 Overlapping lesion of stomach	0.002	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
C16.3 Pyloric antrum	0.002	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.002	0.998	0.000
M62.28 Ischaemic infarction of muscle (Other)	0.002	0.998	0.000
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.002	0.998	0.000
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.24 Ischaemic infarction of muscle (Hand)	0.002	0.998	0.000
M62.23 Ischaemic infarction of muscle (Forearm)	0.002	0.998	0.000
M62.22 Ischaemic infarction of muscle (Upper arm)	0.002	0.998	0.000
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.002	0.998	0.000
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.000	0.998	0.002
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.998	0.001
M62.98 Disorder of muscle, unspecified (Other)	0.002	0.998	0.000
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.002	0.998	0.000
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M62.94 Disorder of muscle, unspecified (Hand)	0.002	0.998	0.000
M62.93 Disorder of muscle, unspecified (Forearm)	0.002	0.998	0.000
M62.92 Disorder of muscle, unspecified (Upper arm)	0.002	0.998	0.000
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.002	0.998	0.000
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.002	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
D30.3 Bladder	0.000	0.998	0.002
H50.5 Heterophoria	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
F40 Phobic anxiety disorders	0.000	0.998	0.002
M62.08 Diastasis of muscle (Other)	0.002	0.998	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.002	0.998	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.002	0.998	0.000
M62.06 Diastasis of muscle (Lower leg)	0.002	0.998	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.04 Diastasis of muscle (Hand)	0.002	0.998	0.000
M62.03 Diastasis of muscle (Forearm)	0.002	0.998	0.000
M62.02 Diastasis of muscle (Upper arm)	0.002	0.998	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.002	0.998	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.002	0.998	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.000	0.998	0.002
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.002	0.998	0.000
M62.38 Immobility syndrome (paraplegic) (Other)	0.002	0.998	0.000
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.002	0.998	0.000
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.002	0.998	0.000
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.002	0.998	0.000
M62.34 Immobility syndrome (paraplegic) (Hand)	0.002	0.998	0.000
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.002	0.998	0.000
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.002	0.998	0.000
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.002	0.998	0.000
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.002	0.998	0.000
M62.49 Contracture of muscle (Site unspecified)	0.002	0.998	0.000
M62.48 Contracture of muscle (Other)	0.002	0.998	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.002	0.998	0.000
M62.46 Contracture of muscle (Lower leg)	0.002	0.998	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.002	0.998	0.000
M62.44 Contracture of muscle (Hand)	0.002	0.998	0.000
M62.43 Contracture of muscle (Forearm)	0.002	0.998	0.000
M62.42 Contracture of muscle (Upper arm)	0.002	0.998	0.000
M62.41 Contracture of muscle (Shoulder region)	0.002	0.998	0.000
M62.40 Contracture of muscle (Multiple sites)	0.002	0.998	0.000
S05.8 Other injuries of eye and orbit	0.000	0.998	0.002
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.002	0.998	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.002	0.998	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.002	0.998	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.002	0.998	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.002	0.998	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.002	0.998	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.002	0.998	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.002	0.998	0.000
F40.0 Agoraphobia	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
Z82.3 Family history of stroke	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
H50.2 Vertical strabismus	0.000	0.998	0.002
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
E85.8 Other amyloidosis	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.002	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
E85 Amyloidosis	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M43.1 Spondylolisthesis	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
M94.2 Chondromalacia	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.001	0.998	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
F40.1 Social phobias	0.000	0.998	0.002
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.998	0.002
H50.9 Strabismus, unspecified	0.000	0.998	0.002
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.998	0.002
S05 Injury of eye and orbit	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.998	0.001
D12.7 Rectosigmoid junction	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
W18.3 Sports and athletics area	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.000	0.998	0.002
Z92.0 Personal history of contraception	0.000	0.998	0.002
C25.2 Tail of pancreas	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.002
O32.4 Maternal care for high head at term	0.001	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations