TreeWAS – Variant ID: rs215614

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D22.6 Melanocytic naevi of upper limb, including shoulder	0.239	0.761	0.000
G20 Parkinson's disease	0.142	0.858	0.000
I20.0 Unstable angina	0.000	0.886	0.114
N70.1 Chronic salpingitis and oophoritis	0.000	0.929	0.071
G20-G26 Extrapyramidal and movement disorders	0.066	0.934	0.000
R15 Faecal incontinence	0.000	0.936	0.064
G24 Dystonia	0.057	0.943	0.000
N70 Salpingitis and oophoritis	0.000	0.946	0.054
N70.0 Acute salpingitis and oophoritis	0.000	0.951	0.049
G24.9 Dystonia, unspecified	0.049	0.951	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.047	0.952	0.000
G22 Parkinsonism in diseases classified elsewhere	0.047	0.952	0.000
G24.3 Spasmodic torticollis	0.047	0.953	0.000
G21 Secondary Parkinsonism	0.047	0.953	0.000
G24.0 Drug-induced dystonia	0.045	0.955	0.000
G23 Other degenerative diseases of basal ganglia	0.044	0.956	0.000
G24.8 Other dystonia	0.044	0.956	0.000
G24.1 Idiopathic familial dystonia	0.043	0.957	0.000
G24.4 Idiopathic orofacial dystonia	0.041	0.959	0.000
G24.2 Idiopathic nonfamilial dystonia	0.041	0.959	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.959	0.041
G25 Other extrapyramidal and movement disorders	0.039	0.960	0.000
G21.4 Vascular parkinsonism	0.035	0.965	0.000
G21.9 Secondary Parkinsonism, unspecified	0.034	0.965	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.965	0.035
G21.8 Other secondary Parkinsonism	0.033	0.966	0.000
G21.3 Postencephalitic Parkinsonism	0.033	0.966	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.033	0.966	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.032	0.967	0.000
G21.0 Malignant neuroleptic syndrome	0.032	0.968	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.032	0.968	0.000
G23.3 Multiple system atrophy, cerebellar type	0.032	0.968	0.000
G23.2 Striatonigral degeneration	0.032	0.968	0.000
G23.0 Hallervorden-Spatz disease	0.032	0.968	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.032	0.968	0.000
G25.0 Essential tremor	0.032	0.968	0.000
G25.5 Other chorea	0.030	0.970	0.000
G25.2 Other specified forms of tremor	0.030	0.970	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.029	0.971	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.028	0.971	0.000
G25.4 Drug-induced chorea	0.028	0.971	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.028	0.972	0.000
G25.1 Drug-induced tremor	0.028	0.972	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.973	0.027
G25.3 Myoclonus	0.026	0.974	0.000
G24.5 Blepharospasm	0.025	0.975	0.000
I25.2 Old myocardial infarction	0.000	0.979	0.021
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.983	0.017
I25.3 Aneurysm of heart	0.000	0.983	0.017
I20 Angina pectoris	0.000	0.984	0.016
I25 Chronic ischaemic heart disease	0.000	0.984	0.016
J92.9 Pleural plaque without asbestos	0.013	0.987	0.000
I25.4 Coronary artery aneurysm	0.000	0.988	0.012
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.988	0.012
I25.6 Silent myocardial ischaemia	0.000	0.989	0.011
N76 Other inflammation of vagina and vulva	0.000	0.990	0.010
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.990	0.010
I20-I25 Ischaemic heart diseases	0.000	0.990	0.010
I20.9 Angina pectoris, unspecified	0.000	0.990	0.010
N76.0 Acute vaginitis	0.000	0.990	0.010
N73 Other female pelvic inflammatory diseases	0.000	0.991	0.009
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.991	0.009
G25.8 Other specified extrapyramidal and movement disorders	0.009	0.991	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.991	0.009
N76.4 Abscess of vulva	0.000	0.991	0.009
H61.8 Other specified disorders of external ear	0.009	0.991	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.000	0.991	0.008
N76.6 Ulceration of vulva	0.000	0.991	0.008
H02.8 Other specified disorders of eyelid	0.000	0.992	0.008
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.992	0.008
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.992	0.008
F52.2 Failure of genital response	0.000	0.992	0.008
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.992	0.008
N76.2 Acute vulvitis	0.000	0.992	0.008
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.992	0.008
N76.3 Subacute and chronic vulvitis	0.000	0.992	0.007
N76.5 Ulceration of vagina	0.000	0.992	0.007
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.993	0.007
N76.1 Subacute and chronic vaginitis	0.000	0.993	0.007
Y40.8 Other systemic antibiotics	0.007	0.993	0.000
N73.4 Female chronic pelvic peritonitis	0.000	0.993	0.007
N73.3 Female acute pelvic peritonitis	0.000	0.993	0.007
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.993	0.007
N75 Diseases of Bartholin's gland	0.000	0.993	0.007
H61.2 Impacted cerumen	0.007	0.993	0.000
H61 Other disorders of external ear	0.007	0.993	0.000
N73.5 Female pelvic peritonitis, unspecified	0.000	0.993	0.007
N76.8 Other specified inflammation of vagina and vulva	0.000	0.993	0.006
H61.1 Non-infective disorders of pinna	0.006	0.994	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.000	0.994	0.006
N74.4 Female chlamydial pelvic inflammatory disease	0.000	0.994	0.006
N74.3 Female gonococcal pelvic inflammatory disease	0.000	0.994	0.006
N74.2 Female syphilitic pelvic inflammatory disease	0.000	0.994	0.006
N74.1 Female tuberculous pelvic inflammatory disease	0.000	0.994	0.006
N74.0 Tuberculous infection of cervix uteri	0.000	0.994	0.006
L57.0 Actinic keratosis	0.006	0.994	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.994	0.006
Y40 Systemic antibiotics	0.006	0.994	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.994	0.006
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
J44 Other chronic obstructive pulmonary disease	0.000	0.994	0.006
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
H61.9 Disorder of external ear, unspecified	0.006	0.994	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.006	0.994	0.000
J92 Pleural plaque	0.006	0.994	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.994	0.006
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.994	0.006
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.994	0.006
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.994	0.006
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.994	0.006
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.994	0.006
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.994	0.006
J43.9 Emphysema, unspecified	0.000	0.994	0.006
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.994	0.006
K37 Unspecified appendicitis	0.000	0.994	0.006
I23.8 Other current complications following acute myocardial infarction	0.000	0.994	0.006
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.994	0.005
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.994	0.005
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.994	0.005
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.994	0.005
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.994	0.005
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.994	0.005
Y40.3 Macrolides	0.006	0.994	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.994	0.005
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
I20.1 Angina pectoris with documented spasm	0.000	0.995	0.005
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.995	0.005
I25.5 Ischaemic cardiomyopathy	0.000	0.995	0.005
N75.8 Other diseases of Bartholin's gland	0.000	0.995	0.005
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.995	0.005
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.995	0.005
Y40.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.995	0.005
I24 Other acute ischaemic heart diseases	0.000	0.995	0.005
Y40.5 Aminoglycosides	0.005	0.995	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.005	0.995	0.000
H61.3 Acquired stenosis of external ear canal	0.005	0.995	0.000
Y40.0 Penicillins	0.005	0.995	0.000
Y40.2 Chloramphenicol group	0.005	0.995	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.995	0.005
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.995	0.004
N71 Inflammatory disease of uterus, except cervix	0.000	0.995	0.004
Y40.6 Rifamycins	0.004	0.996	0.000
Y40.4 Tetracyclines	0.004	0.996	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.996	0.004
E78.8 Other disorders of lipoprotein metabolism	0.000	0.996	0.004
I22 Subsequent myocardial infarction	0.000	0.996	0.004
D10.3 Other and unspecified parts of mouth	0.004	0.996	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.004	0.996	0.000
K36 Other appendicitis	0.000	0.996	0.004
H81.0 Meniere's disease	0.004	0.996	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.996	0.004
N75.0 Cyst of Bartholin's gland	0.000	0.996	0.004
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.996	0.004
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.996	0.003
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.996	0.003
F52.7 Excessive sexual drive	0.000	0.996	0.003
F52.6 Nonorganic dyspareunia	0.000	0.996	0.003
F52.5 Nonorganic vaginismus	0.000	0.996	0.003
F52.4 Premature ejaculation	0.000	0.996	0.003
F52.3 Orgasmic dysfunction	0.000	0.996	0.003
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.996	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.996	0.003
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
M23.8 Other internal derangements of knee	0.000	0.997	0.003
N71.1 Chronic inflammatory disease of uterus	0.000	0.997	0.003
F52.0 Lack or loss of sexual desire	0.000	0.997	0.003
N72 Inflammatory disease of cervix uteri	0.000	0.997	0.003
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
S82.40 Fracture of fibula alone (closed)	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.997	0.003
I24.1 Dressler's syndrome	0.000	0.997	0.003
N71.0 Acute inflammatory disease of uterus	0.000	0.997	0.002
K35-K38 Diseases of appendix	0.000	0.997	0.003
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.003
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.997	0.003
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.997	0.003
D10.1 Tongue	0.003	0.997	0.000
I25.1 Atherosclerotic heart disease	0.000	0.997	0.003
L72.0 Epidermal cyst	0.000	0.997	0.003
D10 Benign neoplasm of mouth and pharynx	0.003	0.997	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
R59.1 Generalised enlarged lymph nodes	0.000	0.997	0.003
F30.9 Manic episode, unspecified	0.003	0.997	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.002
E78.4 Other hyperlipidaemia	0.000	0.997	0.003
K05.3 Chronic periodontitis	0.003	0.997	0.000
Z98.1 Arthrodesis status	0.003	0.997	0.000
D10.9 Pharynx, unspecified	0.002	0.998	0.000
E78.6 Lipoprotein deficiency	0.000	0.998	0.002
D10.0 Lip	0.002	0.998	0.000
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
J43 Emphysema	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.998	0.002
D10.7 Hypopharynx	0.002	0.998	0.000
D10.6 Nasopharynx	0.002	0.998	0.000
D10.2 Floor of mouth	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.998	0.002
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
D10.4 Tonsil	0.002	0.998	0.000
E78.3 Hyperchylomicronaemia	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
K04.6 Periapical abscess with sinus	0.000	0.998	0.002
D10.5 Other parts of oropharynx	0.002	0.998	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.998	0.002
N80.1 Endometriosis of ovary	0.002	0.998	0.000
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
K38.9 Disease of appendix, unspecified	0.000	0.998	0.002
G47.8 Other sleep disorders	0.002	0.998	0.000
Q51.2 Other doubling of uterus	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
F55 Abuse of non-dependence-producing substances	0.000	0.998	0.002
J43.1 Panlobular emphysema	0.000	0.998	0.002
J43.0 MacLeod's syndrome	0.000	0.998	0.002
F51 Nonorganic sleep disorders	0.000	0.998	0.002
K38 Other diseases of appendix	0.000	0.998	0.002
F42 Obsessive-compulsive disorder	0.002	0.998	0.000
J43.8 Other emphysema	0.000	0.998	0.002
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
L57 Skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
F51.0 Nonorganic insomnia	0.000	0.998	0.002
F51.5 Nightmares	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
N71.9 Inflammatory disease of uterus, unspecified	0.001	0.998	0.001
D06.9 Cervix, unspecified	0.000	0.998	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
F42.2 Mixed obsessional thoughts and acts	0.002	0.998	0.000
K38.0 Hyperplasia of appendix	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
F42.8 Other obsessive-compulsive disorders	0.001	0.998	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.000	0.998	0.001
F51.8 Other nonorganic sleep disorders	0.000	0.998	0.001
F51.2 Nonorganic disorder of the sleep-wake schedule	0.000	0.998	0.001
F51.1 Nonorganic hypersomnia	0.000	0.998	0.001
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
K38.3 Fistula of appendix	0.000	0.998	0.001
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.998	0.000
F51.4 Sleep terrors [night terrors]	0.000	0.998	0.001
F53.9 Puerperal mental disorder, unspecified	0.000	0.998	0.001
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.001
H83.0 Labyrinthitis	0.000	0.998	0.002
K56.4 Other impaction of intestine	0.000	0.998	0.002
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
F50 Eating disorders	0.000	0.998	0.002
Z80.3 Family history of malignant neoplasm of breast	0.000	0.998	0.002
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.001
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.001
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.001
Y54.7 Agents affecting calcification	0.002	0.998	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.001
J86.9 Pyothorax without fistula	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.998	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.998	0.001
Q50.2 Congenital torsion of ovary	0.000	0.998	0.001
Q50.1 Developmental ovarian cyst	0.000	0.998	0.001
Q50.0 Congenital absence of ovary	0.000	0.998	0.001
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
J86.0 Pyothorax with fistula	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.001	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.001	0.998	0.000
L57.1 Actinic reticuloid	0.001	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
C82.2 Large cell, follicular	0.000	0.998	0.002
F51.3 Sleepwalking [somnambulism]	0.000	0.998	0.001
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
L57.5 Actinic granuloma	0.001	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
Z74.0 Reduced mobility	0.002	0.998	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.998	0.001
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.998	0.002
K38.2 Diverticulum of appendix	0.000	0.998	0.001
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.001
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.001
D22 Melanocytic naevi	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.001
E61.2 Magnesium deficiency	0.001	0.998	0.000
F42.1 Predominantly compulsive acts [obsessional rituals]	0.001	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.001	0.998	0.000
J43.2 Centrilobular emphysema	0.000	0.998	0.001
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.001
F50.2 Bulimia nervosa	0.000	0.999	0.001
H04.2 Epiphora	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.999	0.000
Y54.0 Mineralocorticoids	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.001	0.999	0.000
L03.8 Cellulitis of other sites	0.000	0.999	0.001
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.001	0.999	0.000
R50.0 Fever with chills	0.001	0.999	0.000
S63.6 Sprain and strain of finger(s)	0.001	0.999	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
F50.8 Other eating disorders	0.000	0.999	0.001
F50.5 Vomiting associated with other psychological disturbances	0.000	0.999	0.001
F50.4 Overeating associated with other psychological disturbances	0.000	0.999	0.001
F50.3 Atypical bulimia nervosa	0.000	0.999	0.001
F50.1 Atypical anorexia nervosa	0.000	0.999	0.001
K14.0 Glossitis	0.000	0.999	0.001
M66.2 Spontaneous rupture of extensor tendons	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.999	0.001
L57.4 Cutis laxa senilis	0.001	0.999	0.000
G30 Alzheimer's disease	0.001	0.999	0.000
I60 Subarachnoid haemorrhage	0.001	0.999	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.999	0.001
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.999	0.001
M46.40 Discitis, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.999	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.999	0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.999	0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M46.4 Discitis, unspecified	0.000	0.999	0.001
Q50.5 Embryonic cyst of broad ligament	0.000	0.999	0.001
E61 Deficiency of other nutrient elements	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.999	0.000
I78.1 Naevus, nonneoplastic	0.001	0.999	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.999	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.001	0.999	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.001	0.999	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H62.2 Otitis externa in mycoses	0.001	0.999	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.001	0.999	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.999	0.001
S82.4 Fracture of fibula alone	0.001	0.999	0.000
J86 Pyothorax	0.001	0.999	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
N36.9 Urethral disorder, unspecified	0.001	0.999	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.999	0.001
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.999	0.001
Q51.6 Embryonic cyst of cervix	0.000	0.999	0.001
Q51.5 Agenesis and aplasia of cervix	0.000	0.999	0.001
Q51.4 Unicornate uterus	0.000	0.999	0.001
Q51.0 Agenesis and aplasia of uterus	0.000	0.999	0.001
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
C22.0 Liver cell carcinoma	0.001	0.999	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.999	0.001
F50.0 Anorexia nervosa	0.000	0.999	0.001
J93.1 Other spontaneous pneumothorax	0.001	0.999	0.000
K38.8 Other specified diseases of appendix	0.000	0.999	0.001
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.001	0.999	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.999	0.001
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.999	0.000
C24.0 Extrahepatic bile duct	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.001	0.999	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.999	0.001
M46.47 Discitis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.999	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.999	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.999	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.999	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.999	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.001	0.999	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.999	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.001	0.999	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M46.45 Discitis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.43 Discitis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
E61.9 Deficiency of nutrient element, unspecified	0.001	0.999	0.000
E61.8 Deficiency of other specified nutrient elements	0.001	0.999	0.000
E61.7 Deficiency of multiple nutrient elements	0.001	0.999	0.000
E61.6 Vanadium deficiency	0.001	0.999	0.000
E61.5 Molybdenum deficiency	0.001	0.999	0.000
E61.4 Chromium deficiency	0.001	0.999	0.000
E61.3 Manganese deficiency	0.001	0.999	0.000
E61.0 Copper deficiency	0.001	0.999	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.999	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.999	0.001
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.999	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.999	0.001
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.999	0.001
Z03.4 Observation for suspected myocardial infarction	0.000	0.999	0.001
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.999	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.999	0.000
J32.8 Other chronic sinusitis	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.001	0.999	0.000
D23.4 Skin of scalp and neck	0.001	0.999	0.000
F50.9 Eating disorder, unspecified	0.000	0.999	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.000	0.999	0.001
M46.49 Discitis, unspecified (Site unspecified)	0.000	0.999	0.001
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
H50.2 Vertical strabismus	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.001	0.999	0.000
Q51.3 Bicornate uterus	0.000	0.999	0.001
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
S63.3 Traumatic rupture of ligament of wrist and carpus	0.001	0.999	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
M46.42 Discitis, unspecified (Cervical region)	0.000	0.999	0.001
J37.0 Chronic laryngitis	0.000	0.999	0.001
H81 Disorders of vestibular function	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations